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Neurological diseases, wide definition

NEURODIS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

None

0 out of 7 registries used, show all original rules.

0

4. Check minimum number of events

None

0

5. Include endpoints

235798

6. Filter based on genotype QC (FinnGen only)

235798

Control definitions (FinnGen only)

Control exclude
IBD_COMORB

Extra metadata

First used in FinnGen datafreeze
DF12

Case counts by codes

FinnGen case counts by registry codes:

No data for upset plot.

No data for upset table.

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 235798 126868 108930
Unadjusted period prevalence (%) 45.45 43.24 48.02
Median age at first event (years) 53.34 50.57 56.57

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
4944
13896
1.99
316.22
3.7
2.4
—
—
—
0
0
1333
1907
3.66
313.80
5.8
4.4
—
—
—
0
0
5401
15709
1.94
313.29
4.6
3.1
—
—
—
0
0
933
996
4.85
310.13
1.8
1.2
1.2
1.2
g/l
1.19
888
945
1531
2247
3.58
307.65
2.4
2.8
67.0
66.2
g/l
2.67
1418
2083
4001
5976
3.83
307.65
1.3
1.1
7.1
2.3
u/ml
5.99
1595
2508
6214
11416
3.34
307.65
3.6
1.9
8.3
8.5
mmol/l
2.08
5374
9936
7888
18968
2.62
307.65
6.5
5.0
—
—
—
0
0
10063
33322
1.89
307.65
4.2
3.5
—
—
—
0
0
15853
46944
3.04
307.65
4.1
2.3
9.8
8.9
mm/h
15.26
14890
42909
1222
1534
4.16
307.65
5.1
6.1
24.5
24.3
mmol/l
1.61
1155
1472
7033
16645
2.58
307.65
2.8
2.2
54.3
61.0
u/l
10.09
6548
15364
19460
72854
2.79
307.65
5.1
3.3
1.8
2.3
mu/l
3.31
18377
67475
5870
17068
1.96
307.65
4.1
2.4
0.0
0.0
estimate
0.06
2173
5927
4668
10508
2.53
307.65
2.7
2.0
6.6
6.7
e6/l
0.12
4125
8822
8410
26692
1.89
307.65
3.8
2.3
—
—
—
0
0
2970
6165
2.62
307.65
1.8
1.4
—
—
—
0
0
12808
38200
2.46
307.65
9.1
8.0
4.1
3.9
e9/l
16.18
11384
32720
2252
3338
3.63
307.65
2.6
2.4
10.3
10.6
g/l
2.14
2061
3084
7737
16520
2.99
307.65
3.3
2.1
30.9
60.2
ng/l
3.40
4280
7880
4192
9288
2.53
307.65
1.6
1.4
40378620.8
24652822.1
pmol/l
0.77
3596
7983
1138
1123
5.29
307.65
1.3
1.1
0.8
0.5
u/ml
0.46
100
54
5032
13968
2.02
307.65
4.0
2.3
1.0
1.0
kg/l
2.16
714
2244
7825
19136
2.56
307.65
1.9
1.5
97.9
96.8
pmol/l
1.02
4311
10159
8504
25153
2.08
307.65
3.4
2.2
6.2
5.9
ph
—
6
19
6745
18145
2.20
307.65
2.9
3.7
2.3
2.4
mmol/l
4.68
6040
16286
3088
6734
2.49
307.65
2.6
1.8
2.4
2.4
g/l
0.91
2877
6258
6509
16934
2.27
307.65
3.4
2.3
94.3
111.3
e6/l
0.27
5062
11876
9294
21545
2.90
307.65
6.7
5.0
1.2
1.2
mmol/l
2.40
8521
19440
3898
8583
2.53
307.65
3.4
2.7
404.3
919.2
ng/l
5.96
2385
5675
5085
7671
3.95
307.65
4.3
2.1
12.3
10.5
mg/mmol
0.91
3443
4228
15345
58414
1.88
307.65
3.5
2.3
44.7
35.1
u/l
36.34
14589
55683
10723
30251
2.41
307.65
6.7
4.5
2.8
2.9
%
3.82
10110
28107
446
116
19.64
307.65
1.2
1.2
—
—
—
0
0
10652
33842
2.04
307.65
5.0
3.3
0.0
0.0
estimate
1.63
2247
6145
545
154
18.15
307.65
1.2
1.1
40.2
37.6
mg/l
0.25
449
126
3741
5531
3.84
307.65
1.4
1.2
496.9
423.0
titre
1.13
677
776
5925
15251
2.26
307.65
3.1
2.3
—
—
—
0
0
18891
76238
2.14
307.65
4.1
2.7
5.8
5.4
mmol/l
280.91
17583
70786
4486
10222
2.48
307.65
1.5
1.3
20.0
20.2
nmol/l
0.28
3980
8930
2001
2767
3.87
307.65
1.3
1.2
53.1
48.9
au/ml
0.19
59
165
2317
4065
3.06
307.65
8.4
7.8
5.1
5.1
kpa
0.00
2219
3878
8025
17659
2.92
307.65
7.7
5.7
1.2
1.2
inr
0.64
2529
5628
3689
6278
3.30
307.65
2.8
2.3
29.6
30.1
s
3.70
3562
6127
2142
3068
3.75
307.65
2.4
2.2
23.2
20.6
au/ml
0.47
120
340
14091
47088
2.21
307.65
4.6
2.9
1550.3
924.6
e6/l
0.68
207
566
4270
6797
3.62
307.65
1.3
1.1
23.8
19.1
iu/ml
0.63
1232
1978
7629
21296
2.17
307.65
3.9
2.6
59.0
89.4
e6/l
3.07
5453
13105
13609
45550
2.15
307.65
3.4
2.5
—
—
—
0
0
21037
79002
3.71
307.65
15.2
7.7
3.9
3.9
mmol/l
11.94
20577
75594
2041
3608
3.01
307.65
8.9
8.3
95.9
96.5
%
2.99
1965
3464
1059
483
11.47
307.65
1.6
1.4
3.6
3.4
mmol/l
6.32
994
460
11134
32391
2.35
307.65
6.7
4.4
29.4
30.1
%
10.48
10524
30243
17556
66245
2.23
307.65
5.3
2.5
38.8
35.6
mmol/mol
311.93
16572
61783
1058
506
10.93
307.65
1.7
1.5
23.1
11.4
e6/l
1.69
820
359
2102
3820
2.93
307.65
5.1
3.8
5.9
5.8
kpa
2.97
2043
3710
21196
82671
3.44
307.65
14.4
7.0
19.8
24.9
mg/l
82.33
17228
57302
10727
34184
2.04
307.65
3.7
2.4
0.0
0.0
estimate
1.71
2153
6108
2846
6090
2.53
307.65
2.7
1.9
23.6
24.3
%
1.31
2455
5332
5123
11869
2.48
307.65
2.6
2.0
2687.4
5069.3
umol/l
4.32
4512
10710
10157
24168
2.92
307.65
7.3
5.2
1.2
1.2
mmol/l
2.11
8647
20341
1330
1633
4.27
307.65
4.9
6.0
—
—
—
0
0
15862
48564
2.88
307.65
7.3
5.9
76.0
78.0
u/l
4.81
15074
45275
528
148
18.28
307.65
1.1
1.1
240.3
223.7
mg/l
0.45
458
133
5319
12039
2.56
307.65
4.4
3.5
—
—
—
0
0
10796
30442
2.42
307.65
6.9
4.7
8.3
8.3
%
0.10
10237
28507
3521
7395
2.63
307.65
4.3
4.0
0.8
0.8
mmol/l
4.41
3287
7004
7145
9678
4.85
307.65
2.4
1.6
246.1
206.6
u/l
0.90
6810
9066
4434
9422
2.67
307.65
3.3
2.5
1220.9
972.5
ng/l
2.51
3588
7873
3446
6518
2.93
307.65
1.7
1.6
1166.3
1143.0
nmol/l
0.62
2685
4806
4360
10049
2.44
307.65
2.9
2.1
553.0
565.0
mosm/kgh2o
2.10
3787
8300
5256
13208
2.28
307.65
3.4
2.6
—
—
—
0
0
1204
546
11.60
307.65
1.6
1.5
468.3
424.8
mg/l
1.42
1145
519
1177
1459
4.21
307.65
2.0
2.3
—
—
—
0
0
11468
31270
2.61
307.65
6.6
4.5
0.6
0.6
e9/l
5.83
10127
26703
1165
1363
4.46
307.65
1.1
1.0
—
—
—
0
0
2082
3798
2.92
307.65
5.2
3.8
1.8
1.7
mmol/l
1.08
1720
3071
9794
31224
1.97
307.65
9.7
6.5
0.0
0.0
e9/l
0.50
8085
25017
12989
33042
3.12
307.65
5.2
3.6
6.5
6.0
mmol/l
95.94
12112
29114
14671
48822
2.31
307.65
4.4
2.8
—
—
—
0
0
21716
89981
3.20
307.65
15.1
7.8
73.2
72.5
umol/l
2.46
21708
89890
8984
24664
2.32
307.65
2.4
1.9
72.5
73.8
nmol/l
4.00
8277
22901
6114
16125
2.21
307.65
2.9
2.1
—
—
—
0
0
993
468
11.06
307.65
1.8
1.5
—
—
—
0
0
5625
15948
2.01
307.65
6.8
6.5
—
—
—
0
0
578
197
15.06
307.65
1.1
1.0
—
—
—
0
0
4914
7238
4.03
307.65
3.5
1.9
478.0
475.8
mg/l
0.01
3329
3920
10996
31826
2.35
307.65
6.5
4.3
56.3
55.5
%
8.40
10426
29877
11511
31349
2.62
307.65
6.6
4.5
0.0
0.0
e9/l
3.66
10155
26748
7851
21897
2.19
307.65
3.4
2.9
31.1
32.3
u/l
0.57
7465
20980
10772
36073
1.90
307.65
3.2
2.4
94.1
86.2
ug/l
2.91
10123
34169
1802
2239
4.29
307.65
4.6
5.2
5.2
5.0
kpa
5.78
1688
2103
21005
78583
3.72
307.65
15.2
7.6
139.6
139.7
mmol/l
22.24
20586
75429
17065
59511
2.52
307.65
4.3
3.0
14.6
14.4
pmol/l
11.67
15907
54046
10430
29017
2.42
307.65
6.7
4.6
0.7
0.7
%
0.82
9847
26985
6273
17280
2.11
307.65
1.4
1.2
1.7
2.2
u/ml
1.46
1739
4695
21631
92719
2.71
307.65
13.3
6.6
—
—
—
0
0
5882
13342
2.61
307.65
4.1
3.2
7.4
7.4
ph
0.07
1181
2425
5946
15177
2.28
307.65
3.2
2.3
0.3
0.4
e6/l
3.24
4539
10292
1789
2225
4.28
307.65
4.6
5.2
7.4
7.4
ph
0.92
211
228
2799
4188
3.66
307.65
2.1
2.4
368.3
393.5
nmol/l
6.88
2606
3911
5461
11416
2.81
307.65
2.2
1.6
1.0
1.3
mg/l
5.03
3954
8306
2128
3938
2.88
307.65
5.1
3.9
7.4
7.4
ph
0.04
17
11
6715
20457
1.90
307.65
2.4
1.9
—
—
—
0
0
2978
6625
2.43
307.65
1.2
1.2
—
—
—
0
0
11822
33189
2.55
307.65
6.6
4.4
2.0
2.0
e9/l
0.32
10622
29002
3077
6483
2.59
307.65
2.2
1.6
—
—
—
0
0
5500
14831
2.12
307.65
1.5
1.3
2.2
2.1
g/l
2.08
3521
9450
5480
13475
2.35
307.65
2.3
2.0
2.8
2.7
mg/l
3.72
4733
11443
10898
29719
2.54
307.65
5.7
6.1
10.8
12.4
umol/l
17.47
10252
28036
2320
4085
3.05
307.65
8.4
7.7
1.1
0.7
mmol/l
4.57
1784
3217
11876
32797
2.62
307.65
6.9
4.8
0.2
0.2
e9/l
0.09
10645
28476
2890
5506
2.86
307.65
7.1
5.3
1.1
1.1
mmol/l
0.68
2697
5173
10675
33577
2.07
307.65
3.7
2.3
0.0
0.0
estimate
0.03
2167
5917
8931
22217
2.62
307.65
4.9
4.6
36.7
36.6
g/l
0.70
8366
20652
2318
4061
3.06
307.65
8.3
7.8
13.0
14.1
kpa
10.89
2222
3874
1057
505
10.94
307.65
1.8
1.6
4548.4
636.3
e6/l
0.59
862
375
5684
14862
2.20
307.65
4.4
3.5
93.3
92.3
%
2.21
5540
14521
21596
92367
2.72
307.65
10.6
5.8
28.4
25.9
u/l
41.85
21077
88791
3391
7504
2.48
307.65
2.6
1.9
14.0
14.7
umol/l
3.91
3160
7005
2508
5344
2.51
307.11
7.5
6.9
104.6
105.0
mmol/l
3.02
2453
5265
895
939
4.93
302.77
2.5
2.3
366.0
382.2
ug/l
0.07
818
885
905
964
4.86
301.42
1.8
1.2
0.2
0.2
g/l
0.70
862
909
1635
2766
3.11
301.39
1.9
1.8
1.2
1.3
g/l
1.19
1528
2560
1775
3166
2.96
300.33
4.7
3.7
4.8
4.8
kpa
0.58
1723
3070
3540
8946
2.16
296.55
2.8
2.2
1.0
1.2
e6/l
1.22
1989
4419
2162
4348
2.64
295.68
17.8
16.1
1.2
1.3
inr
2.91
337
601
1869
3475
2.84
294.53
9.5
8.1
125.0
121.5
g/l
7.90
1804
3335
521
288
9.26
292.09
2.2
1.8
—
—
—
0
0
1307
1944
3.51
291.33
8.0
5.8
24.4
24.4
mmol/l
0.01
1222
1791
522
291
9.18
291.17
1.8
1.7
—
—
—
0
0
446
186
12.24
290.45
2.5
2.1
157.9
97.3
ug/min
0.72
287
95
422
164
13.13
283.82
1.7
1.2
11507.0
18920.8
e6/l
0.53
303
118
17933
75478
1.76
277.57
17.0
9.2
13.5
13.4
%
2.56
17641
73372
1917
3745
2.71
275.98
7.7
7.5
1.4
1.3
mmol/l
1.06
1828
3595
463
231
10.24
275.21
1.4
1.1
—
—
—
0
0
1882
3656
2.72
273.66
9.7
6.0
8.1
7.4
mmol/l
4.73
1817
3523
1658
3047
2.86
265.75
3.6
2.2
—
—
—
0
0
1518
2653
3.00
264.69
2.5
1.8
7.0
10.9
ug/l
5.19
1334
2346
1444
2467
3.06
261.13
4.4
3.5
83.9
74.2
ng/l
2.92
1295
2190
2417
5472
2.35
258.59
6.2
4.0
—
—
—
0
0
5094
15387
1.84
256.48
2.4
1.9
—
—
—
0
0
382
149
13.06
256.46
1.4
1.2
1.9
1.8
mmol/l
0.09
359
140
409
186
11.21
255.25
1.8
1.4
—
—
—
0
0
1868
3756
2.62
254.11
4.4
3.8
0.8
0.9
%
0.46
463
978
22695
104532
2.62
249.99
21.3
10.3
259.2
255.0
e9/l
18.27
22353
100687
1433
2527
2.96
245.78
1.1
1.1
—
—
—
0
0
19181
83293
1.77
245.44
4.4
3.0
2.8
3.0
mmol/l
117.03
18021
78030
479
306
8.00
244.86
3.0
2.2
0.9
0.8
nmol/l
2.32
404
283
1905
3942
2.55
244.83
9.6
8.1
—
—
—
0
0
22704
104739
2.60
244.08
21.1
10.3
30.1
30.0
pg
3.17
22526
102890
3550
9631
2.00
243.46
2.4
2.8
106.7
132.0
ug/g
3.75
2799
7688
22702
104772
2.59
242.20
21.2
10.3
89.9
89.7
fl
11.75
22525
102915
22704
104794
2.59
241.86
21.2
10.3
4.6
4.6
e12/l
3.40
22321
100726
3288
8693
2.04
241.54
2.6
3.3
2.4
2.4
mmol/l
1.00
2867
7631
22710
104845
2.59
241.46
21.3
10.3
6.9
6.5
e9/l
75.11
22331
100716
1112
1684
3.43
240.88
1.9
2.2
39.0
40.9
u/l
1.92
1020
1554
1780
3586
2.61
240.81
4.4
3.9
0.1
0.1
%
0.49
431
916
3345
8915
2.03
240.45
3.0
2.2
3.1
2.8
e6/l
0.82
1802
4406
19013
82546
1.75
238.84
4.1
2.9
4.6
4.9
mmol/l
175.95
18002
77939
1725
3436
2.64
238.37
4.0
3.7
0.5
0.6
%
0.71
335
730
22705
104904
2.57
237.70
21.4
10.4
136.9
137.2
g/l
3.45
22524
103056
18260
78437
1.70
237.10
3.7
2.6
1.3
1.2
mmol/l
147.58
17142
73894
1661
3253
2.68
236.86
3.1
2.6
4.6
4.6
pmol/l
1.47
1497
2908
1003
1432
3.62
235.70
1.5
1.2
10.4
5.9
u/ml
0.65
24
45
18889
81959
1.73
235.34
4.1
2.8
1.4
1.5
mmol/l
227.55
17797
77296
324
108
15.25
232.21
1.6
1.1
—
—
—
0
0
6167
20315
1.70
227.75
3.2
2.1
—
—
—
0
0
5050
15812
1.76
221.72
1.7
1.5
1.5
1.3
mmol/l
36.32
4336
13889
1678
3427
2.57
220.50
4.5
3.9
0.3
0.2
%
0.16
355
788
1232
2143
2.99
215.54
4.0
3.3
132.8
131.4
g/l
1.08
1204
2096
600
604
5.09
211.07
5.4
6.4
372.9
404.3
umol/l
4.00
542
523
1592
3265
2.55
207.12
9.3
8.4
24.7
24.7
mmol/l
0.11
1579
3244
2058
4771
2.27
206.77
3.1
2.7
1.8
1.6
%
9.10
1836
4288
450
337
6.81
205.03
1.1
1.1
19841.7
14.1
iu/ml
0.57
125
86
1898
4261
2.34
204.73
3.8
3.0
—
—
—
0
0
726
897
4.16
204.54
1.2
1.1
36.0
17.0
u/ml
0.75
40
32
852
1196
3.67
204.49
5.3
3.7
—
—
—
0
0
1273
2364
2.80
198.98
10.2
9.9
1.4
1.3
%
6.38
1264
2356
668
793
4.32
197.11
1.3
1.1
11.9
10.3
u/ml
0.12
90
56
757
998
3.90
196.99
4.3
3.3
1.4
1.4
mmol/l
0.01
741
984
291
114
12.96
194.94
1.4
1.1
—
—
—
0
0
2587
6748
2.04
194.05
3.0
3.0
6.9
8.8
umol/l
4.17
2206
5899
1267
2381
2.76
193.81
10.2
10.0
0.7
0.7
%
2.09
1256
2376
243
60
20.52
192.98
1.6
1.1
53.3
60.8
%
0.58
142
33
657
783
4.30
192.98
1.2
1.1
7.9
2.8
u/ml
0.51
62
32
982
1597
3.18
190.81
3.7
3.2
1.4
1.3
%
3.15
976
1591
1254
2395
2.72
186.16
10.4
10.0
93.9
94.8
%
4.30
1247
2387
929
1497
3.20
182.97
4.0
2.6
25.2
25.2
mmol/l
0.13
902
1445
1263
2445
2.68
182.85
5.6
4.4
24.2
24.2
mmol/l
0.10
1156
2289
639
780
4.20
182.50
3.5
3.0
24.4
24.4
mmol/l
0.03
572
693
952
1567
3.13
181.45
3.7
3.2
0.7
0.7
%
0.19
915
1518
1925
4578
2.21
181.36
1.3
1.2
234.7
313.5
u/ml
1.43
1781
4237
1608
3543
2.37
179.84
3.9
2.9
1.2
1.2
mmol/l
1.52
1406
3026
653
828
4.04
178.19
4.6
3.5
3.9
3.8
mmol/l
0.31
614
782
2542
6805
1.98
176.75
1.5
1.3
—
—
—
0
0
3806
11653
1.76
175.29
1.7
1.6
—
—
—
0
0
2343
6139
2.01
172.52
1.2
1.1
—
—
—
0
0
1373
2890
2.47
168.69
3.3
2.6
147.8
176.7
ng/l
1.51
1191
2616
1148
2228
2.67
165.11
3.1
2.3
21.2
21.4
s
0.39
975
1930
1463
3214
2.37
164.25
3.0
2.7
72.8
67.6
e9/l
4.24
1088
2279
648
876
3.79
163.13
2.2
2.0
3.8
3.8
g/l
0.00
469
635
1978
4974
2.09
161.75
2.4
2.6
0.2
0.2
g/l
0.30
1847
4709
573
720
4.07
158.01
3.7
2.7
—
—
—
0
0
2233
5931
1.98
157.70
2.6
2.3
6135.7
7021.5
u/l
0.51
829
2668
631
867
3.72
155.50
2.0
1.2
4.0
2.6
iu/l
2.68
245
220
671
968
3.55
154.89
4.0
2.7
7.4
7.4
ph
1.73
569
790
245
109
11.39
154.56
1.4
1.3
72.6
78.4
%
0.27
30
13
1058
2054
2.66
151.87
10.6
10.7
24.3
24.3
mmol/l
0.01
1003
1960
1502
3463
2.26
151.17
1.4
1.3
—
—
—
0
0
573
753
3.89
149.49
1.2
1.1
49.9
27.1
u/ml
1.45
54
48
584
780
3.83
149.26
3.0
2.8
33.1
36.5
umol/l
1.97
519
685
195
57
17.30
146.66
2.8
1.5
—
—
—
0
0
1691
4158
2.12
145.77
2.6
2.1
4.2
4.1
e9/l
1.24
1396
3462
206
71
14.68
145.70
1.4
1.4
1.5
1.7
nmol/l
0.33
185
64
2059
5467
1.97
144.98
1.3
1.2
135.1
147.1
iu/ml
0.50
757
2051
2072
5520
1.97
144.51
2.6
2.3
57.7
49.2
u/l
0.14
1782
4811
1071
2174
2.54
141.01
3.3
2.2
—
—
—
0
0
209
81
13.05
140.69
1.6
1.0
6.6
5.1
u/l
1.24
172
66
586
821
3.65
140.68
2.2
2.0
10.4
10.5
g/l
0.14
506
703
581
810
3.66
140.39
4.0
2.8
5.0
4.9
kpa
1.37
569
790
581
810
3.66
140.39
4.0
2.8
2.1
2.3
mmol/l
0.67
358
493
1253
2755
2.35
139.90
1.5
1.3
—
—
—
0
0
580
814
3.64
138.91
4.0
2.8
9.1
9.0
kpa
0.17
568
794
786
1358
2.97
138.25
6.1
6.2
9.0
9.0
kpa
0.44
730
1294
143
16
45.12
134.48
2.6
2.6
28.7
26.2
umol/l
—
103
10
726
1217
3.06
134.08
2.2
1.8
1.7
2.3
ug/l
0.47
647
1087
184
61
15.25
132.16
1.5
1.1
37.2
33.1
%
0.32
109
36
527
730
3.68
128.41
2.6
1.8
17.0
17.1
%
0.15
273
317
386
411
4.77
128.14
1.4
1.1
—
—
—
0
0
779
1402
2.85
127.84
6.7
4.4
0.9
0.9
%
0.09
726
1296
437
528
4.21
126.19
2.8
2.5
—
—
—
0
0
784
1429
2.81
125.85
6.6
4.4
1.8
1.7
%
0.74
730
1313
642
1037
3.16
125.62
1.4
1.3
305.2
296.8
ug/g
0.33
331
573
504
697
3.69
123.06
2.2
2.0
38.5
38.5
g/l
0.02
446
606
175
65
13.60
120.03
1.4
1.1
146084.7
88044.7
e6/l
0.33
118
43
19523
89409
1.51
119.75
15.1
8.0
40.4
40.6
%
1.40
15257
74775
163
51
16.14
119.67
1.1
1.0
—
—
—
0
0
627
1033
3.10
118.94
1.3
1.3
4.7
3.7
iu/ml
—
9
11
2040
5788
1.84
117.04
2.5
1.9
11.8
12.7
nmol/l
4.57
1814
5283
221
134
8.34
116.93
1.1
1.1
5.5
1.9
nmol/l
0.79
42
21
350
372
4.78
116.42
1.6
1.2
1.3
1.5
promille
1.52
267
288
2258
6634
1.78
115.77
4.0
2.9
30.9
32.4
%
8.27
1729
4493
1044
2300
2.34
115.68
11.9
9.7
—
—
—
0
0
661
1147
2.95
115.30
2.0
2.1
10.8
10.0
mg/l
0.98
619
1090
691
1253
2.82
111.84
7.3
4.7
1.3
1.2
mmol/l
0.20
603
1095
271
230
5.97
111.54
1.7
1.1
30.8
14.8
iu/ml
—
21
5
1190
2825
2.17
111.04
1.1
1.1
1.0
15.4
u/ml
0.95
13
41
813
1650
2.52
106.73
1.8
1.8
1.5
1.3
g/l
4.23
708
1404
7770
30737
1.40
105.83
2.0
1.9
—
—
—
0
0
539
873
3.15
104.97
1.3
1.2
4.6
4.0
u/ml
0.33
252
407
1512
4020
1.95
104.82
1.3
1.2
—
—
—
0
0
711
1359
2.68
104.67
3.0
2.8
—
—
—
0
0
2036
5999
1.77
102.79
4.0
2.5
—
—
—
0
0
293
297
5.00
102.32
1.3
1.2
—
—
—
0
0
176
93
9.56
101.31
1.1
1.1
215.0
1067.4
ng/l
0.49
38
25
1279
3243
2.03
100.88
1.6
1.4
8.1
8.5
u/l
0.48
1037
2567
2362
7319
1.69
99.83
1.5
1.5
—
—
—
0
0
1532
4164
1.90
99.51
3.8
2.0
—
—
—
0
0
138
5
139.66
99.44
2.5
1.0
—
—
—
0
0
2245
6880
1.70
98.71
1.3
1.4
—
—
—
0
0
703
1378
2.61
98.69
1.4
1.3
—
—
—
0
0
409
572
3.63
98.39
2.1
1.5
1.7
1.8
mmol/l
0.10
399
559
708
1401
2.58
97.60
2.1
1.7
193.7
204.4
pmol/l
1.23
673
1354
329
401
4.16
94.07
1.2
1.1
56.7
27.3
u/ml
0.82
24
19
542
944
2.93
93.91
1.2
1.2
—
—
—
0
0
1069
2616
2.10
92.27
3.0
2.0
0.3
0.3
e6/l
0.01
1039
2529
18166
83267
1.39
90.63
17.9
8.9
333.7
333.7
g/l
0.07
18059
82388
1510
4216
1.85
90.20
1.2
1.2
—
—
—
0
0
519
904
2.92
89.92
1.1
1.1
116.1
113.1
%
1.14
480
803
351
475
3.75
88.20
3.0
2.1
1.3
1.3
e9/l
0.03
196
292
608
1180
2.63
86.93
1.6
1.6
—
—
—
0
0
423
663
3.24
86.61
3.2
3.4
51.8
33.9
mg/l
0.63
343
558
423
665
3.23
86.22
3.2
3.4
50.0
45.3
mg/l
0.36
346
560
143
70
10.31
85.94
1.6
3.2
1.3
1.4
nmol/l
0.37
118
64
412
639
3.27
85.69
3.2
3.4
2.6
3.5
ratio
0.15
42
53
144
72
10.09
85.55
1.3
1.3
12.4
15.4
%
—
17
10
1681
4932
1.76
85.46
2.8
1.7
—
—
—
0
0
166
108
7.76
83.89
1.4
1.4
132.4
135.3
nmol/l
0.21
166
108
473
816
2.95
83.27
9.0
6.1
105.6
105.2
mmol/l
0.81
423
717
712
1530
2.38
83.00
1.2
1.4
620.0
1095.6
titre
1.21
21
43
472
816
2.94
82.80
9.0
6.0
11.4
11.1
mmol/l
0.69
422
717
1433
4046
1.83
82.47
1.1
1.1
206.2
247.7
titre
0.19
30
150
2294
7395
1.62
82.44
1.4
1.3
—
—
—
0
0
1581
4607
1.77
82.13
1.7
1.6
309.1
332.0
mu/l
0.92
1426
4090
401
639
3.19
80.09
2.4
3.1
22.2
22.0
nmol/l
0.11
381
620
345
497
3.52
79.76
1.4
1.7
65.8
67.1
mmol/l
0.16
296
383
428
714
3.04
79.58
1.6
1.5
—
—
—
0
0
286
357
4.06
79.54
1.5
1.9
284.0
280.9
mosm/kgh2o
1.12
223
302
517
967
2.72
79.14
3.5
3.6
56.6
56.1
%
0.37
517
967
717
1586
2.31
78.47
1.2
1.4
112.2
149.9
titre
0.32
77
145
973
2454
2.03
77.50
2.0
1.5
35.9
43.0
nmol/l
13.54
946
2426
765
1751
2.23
77.48
3.4
3.5
0.3
0.2
g/l
3.00
361
936
305
410
3.77
77.35
7.9
6.4
10.5
10.3
mg/l
0.15
281
389
381
602
3.21
77.09
2.4
2.3
—
—
—
0
0
326
463
3.57
76.87
1.4
1.2
—
—
—
0
0
145
88
8.31
76.77
2.4
1.9
15.6
13.7
umol/l
0.78
145
88
510
966
2.69
76.30
2.3
1.9
133.6
133.3
g/l
0.10
397
758
352
536
3.33
75.25
1.2
1.3
0.2
0.1
nmol/l
0.60
17
18
411
693
3.01
75.14
3.5
2.3
—
—
—
0
0
462
836
2.81
75.01
1.6
1.6
0.7
0.8
g/l
0.40
343
646
330
482
3.47
74.87
2.0
1.5
91.1
90.8
%
0.43
324
476
117
51
11.57
74.67
1.1
1.0
—
—
—
0
0
998
2580
1.98
74.33
1.7
1.7
—
—
—
0
0
321
463
3.51
74.11
1.4
1.2
0.4
0.4
g/l
0.32
219
319
321
464
3.51
73.89
1.4
1.2
2.9
3.0
g/l
0.18
219
320
327
480
3.45
73.68
1.3
1.3
—
—
—
0
0
321
466
3.49
73.46
1.4
1.2
6.4
6.7
g/l
0.76
221
320
6724
27171
1.34
73.39
2.1
2.0
—
—
—
0
0
4493
17031
1.40
73.21
4.0
4.3
2.1
3.3
ug/l
3.31
4021
15644
284
379
3.79
72.72
3.2
2.1
546.5
568.2
e6/l
0.19
229
286
138
85
8.19
72.39
2.2
1.8
640.0
717.4
ml
0.78
96
63
941
2407
2.00
72.12
1.7
1.6
—
—
—
0
0
352
553
3.23
71.86
1.2
1.3
0.6
0.6
nmol/l
0.33
341
530
221
245
4.56
70.43
1.1
1.0
—
—
—
0
0
915
2343
2.00
69.90
2.3
2.2
—
—
—
0
0
178
160
5.62
69.79
1.2
1.1
44.8
27.4
u/ml
—
10
10
467
897
2.64
68.10
4.0
4.3
—
—
—
0
0
275
377
3.69
68.03
3.2
2.2
0.2
0.2
e9/l
0.74
227
288
314
480
3.31
66.79
3.2
3.5
—
—
—
0
0
188
188
5.05
66.67
3.7
2.1
191.5
139.5
umol/l
0.95
103
91
303
454
3.38
66.35
1.5
1.8
—
—
—
0
0
1012
2740
1.89
65.94
1.8
1.7
—
—
—
0
0
283
407
3.52
65.65
2.8
1.8
73.6
70.4
%
1.85
273
396
1901
6172
1.59
65.64
2.7
1.6
—
—
—
0
0
1266
3686
1.76
65.58
1.3
1.3
—
—
—
0
0
5345
21168
1.34
65.23
1.8
1.7
—
—
—
0
0
549
1172
2.38
64.88
1.2
1.2
—
—
—
0
0
712
1703
2.13
64.87
7.5
5.1
1.4
1.1
mg/l
12.70
676
1610
277
405
3.46
62.82
2.8
1.8
11.8
11.9
%
0.03
162
264
162
150
5.45
61.87
1.1
1.1
—
—
—
0
0
1311
3930
1.71
61.32
2.8
2.1
—
—
—
0
0
833
2174
1.96
60.31
4.3
2.6
3.4
3.5
g/l
0.83
786
2077
2002
6724
1.54
59.50
2.6
1.6
—
—
—
0
0
2804
10112
1.44
58.93
1.8
2.0
—
—
—
0
0
2012
6802
1.53
57.99
2.6
1.6
—
—
—
0
0
585
1356
2.19
57.50
1.4
1.3
19.4
22.8
u/l
1.66
485
1148
2005
6799
1.52
56.95
2.4
1.6
—
—
—
0
0
262
396
3.35
56.72
3.1
2.4
858.0
692.5
e6/l
1.82
107
98
115
79
7.34
56.06
2.1
1.9
497.0
510.4
min
0.46
85
59
282
452
3.16
55.94
5.7
2.1
7.0
5.9
mmol/l
5.75
242
356
182
210
4.38
55.59
3.3
1.8
91.0
56.1
mg/l
0.50
138
133
691
1748
2.01
54.49
9.4
5.4
—
—
—
0
0
241
354
3.44
54.36
3.3
2.7
—
—
—
0
0
1958
6721
1.50
52.35
2.5
1.6
—
—
—
0
0
645
1622
2.02
51.68
1.5
1.4
—
—
—
0
0
325
597
2.76
51.49
1.6
1.8
55.8
72.0
mu/l
0.43
295
548
309
553
2.83
51.25
1.5
1.5
322.9
357.3
pmol/l
0.52
244
430
670
1714
1.99
51.25
1.3
1.3
243.8
227.9
u/ml
0.73
431
1087
257
412
3.15
51.01
1.1
1.0
286.1
289.9
mg/l
0.25
235
389
185
235
3.97
50.53
1.2
1.1
24.0
7.5
u/ml
0.60
24
20
361
712
2.57
50.15
3.3
2.2
1.5
1.4
mmol/l
0.98
352
696
710
1870
1.93
50.06
1.2
1.1
—
—
—
0
0
298
530
2.84
49.97
3.6
3.4
30.0
24.0
mu/l
1.21
285
495
238
369
3.26
49.70
1.1
1.1
1.0
1.1
ratio
0.36
87
130
116
95
6.15
49.41
1.0
1.0
268.2
303.6
ng/l
0.46
75
73
279
482
2.93
49.15
3.6
2.0
—
—
—
0
0
641
1642
1.99
48.86
1.5
1.3
20.8
19.1
u/ml
0.11
13
30
95
63
7.59
47.52
2.2
1.2
—
—
—
0
0
291
529
2.78
47.01
2.9
2.1
48.3
38.2
%
3.19
43
35
113
96
5.93
46.69
1.0
1.0
723.5
811.8
ng/l
0.69
71
66
869
2502
1.77
46.55
1.2
1.2
—
—
—
0
0
480
1132
2.15
45.31
1.1
1.1
—
—
—
0
0
847
2440
1.77
45.28
3.2
2.4
—
—
—
0
0
157
191
4.15
45.22
1.6
1.5
3.8
3.0
nmol/l
0.17
121
158
330
662
2.52
44.40
3.4
2.2
7.4
6.3
mmol/l
6.31
323
651
499
1207
2.10
44.25
1.1
1.1
—
—
—
0
0
298
568
2.65
44.22
1.7
1.5
—
—
—
0
0
298
568
2.65
44.22
1.7
1.5
—
—
—
0
0
828
2387
1.77
44.15
1.1
1.1
4.4
5.8
u/ml
0.57
109
453
298
569
2.65
44.07
1.7
1.5
—
—
—
0
0
298
569
2.65
44.07
1.7
1.5
—
—
—
0
0
600
1572
1.94
42.96
1.5
1.4
107.1
103.6
u/ml
0.42
123
309
137
156
4.43
42.58
1.2
1.1
4.2
2.9
iu/ml
1.43
17
20
109
99
5.55
42.50
1.8
1.8
—
—
—
0
0
753
2138
1.79
42.22
1.2
1.1
—
—
—
0
0
296
582
2.57
41.44
1.2
1.3
29.8
33.3
u/l
0.15
260
513
1590
5480
1.49
41.35
1.4
1.4
19.8
25.1
iu/l
8.95
1348
4598
186
277
3.39
41.27
3.2
1.8
12.2
15.4
%
1.46
180
266
6765
28966
1.24
41.18
1.6
1.6
—
—
—
0
0
137
161
4.29
41.12
41.2
36.8
7.5
7.3
ug/l
0.51
126
144
139
170
4.12
39.84
2.5
2.2
52.5
121.4
umol/l
3.01
28
36
147
190
3.90
39.41
2.0
1.9
1.2
1.2
g/24h
0.05
12
17
157
216
3.67
38.87
3.2
1.8
222.1
576.3
e6/l
1.25
89
112
3562
14203
1.30
38.64
1.6
1.4
—
—
—
0
0
150
203
3.73
37.95
2.0
2.3
—
—
—
0
0
3463
13811
1.30
37.39
3.7
3.6
21.2
21.1
%
0.13
1365
6132
194
321
3.05
36.79
2.8
1.9
—
—
—
0
0
49
15
16.43
36.34
1.2
1.1
38.3
33.1
g/l
—
26
9
82
65
6.35
35.97
1.4
1.3
124.7
94.5
nmol/l
0.80
61
44
255
500
2.58
35.96
10.5
11.8
0.6
0.6
mmol/l
1.90
232
457
116
134
4.36
35.56
2.3
1.8
—
—
—
0
0
135
178
3.82
35.35
23.2
24.5
112.8
147.9
ug/l
2.61
108
160
244
472
2.61
35.32
2.1
1.6
26.7
31.7
mg/l
0.47
63
118
131
170
3.88
35.00
1.2
1.1
—
—
—
0
0
150
216
3.50
34.97
1.3
1.2
401.7
404.4
u/l
0.01
137
207
192
328
2.95
34.61
1.1
1.0
1491.8
1340.3
miu/ml
0.91
192
328
54
24
11.32
34.24
1.1
1.0
—
—
—
0
0
54
24
11.32
34.24
1.1
1.0
—
—
—
0
0
54
24
11.32
34.24
1.1
1.0
—
—
—
0
0
135
183
3.72
34.14
1.1
1.1
—
—
—
0
0
77
61
6.35
33.82
11.0
18.4
—
—
—
0
0
295
642
2.32
33.64
3.4
3.1
1.0
1.8
%
2.95
234
498
91
88
5.21
33.55
1.1
1.1
—
—
—
0
0
241
476
2.56
33.55
1.4
1.4
11.0
10.9
umol/l
0.13
228
448
208
380
2.76
33.46
3.1
2.9
0.8
0.8
nmol/l
0.54
163
282
98
103
4.79
33.28
1.2
1.3
0.1
0.6
g/l
—
6
9
132
180
3.70
33.13
1.3
1.3
—
—
—
0
0
171
280
3.08
33.03
3.2
1.8
27.4
27.3
%
0.03
166
270
231
452
2.58
32.76
3.4
3.0
—
—
—
0
0
52
24
10.90
32.36
1.0
1.0
—
—
—
0
0
179
306
2.95
32.27
2.2
2.6
1.8
1.7
umol/l
0.36
170
295
495
1349
1.86
31.65
1.1
1.1
8.8
12.2
au/ml
0.64
29
126
424
1099
1.95
31.40
1.7
2.0
3560.0
2921.2
titre
0.12
14
66
121
161
3.79
31.38
1.5
1.2
14.2
13.7
pmol/l
0.72
102
141
105
125
4.23
31.16
4.8
3.8
—
—
—
0
0
168
283
2.99
31.04
2.5
3.4
1.1
1.4
ug/l
1.19
151
275
366
904
2.05
30.89
1.5
1.3
—
—
—
0
0
110
138
4.01
30.70
1.2
1.1
—
—
—
0
0
337
809
2.11
30.59
1.1
1.1
1.5
1.5
g/l
0.09
306
760
486
1332
1.85
30.55
2.0
2.3
6.6
7.5
titre
—
9
49
80
76
5.30
30.04
2.6
2.7
—
—
—
0
0
60
40
7.54
30.01
2.9
2.1
1.4
1.2
mmol/l
0.21
43
22
94
106
4.46
29.67
1.5
1.7
—
—
—
0
0
455
1242
1.85
28.98
2.0
1.7
—
—
—
0
0
139
217
3.23
28.95
1.3
1.7
36.5
38.2
mmol/l
0.28
127
199
97
118
4.14
28.12
1.4
1.3
16.9
17.0
umol/l
0.06
87
111
430
1170
1.86
27.68
1.2
1.2
—
—
—
0
0
130
201
3.26
27.49
1.2
1.2
0.3
0.3
g/l
0.30
104
149
40
16
12.57
26.67
1.6
1.4
—
—
—
0
0
490
1406
1.76
26.64
1.1
1.1
—
—
—
0
0
206
425
2.45
26.42
2.8
2.5
—
—
—
0
0
86
101
4.29
26.00
2.2
1.9
—
—
—
0
0
49
30
8.21
25.97
1.7
1.2
—
—
—
0
0
1179
4194
1.43
25.88
1.3
1.3
227.1
238.7
miu/ml
0.49
565
2139
97
127
3.84
25.76
2.0
1.7
—
—
—
0
0
214
458
2.36
25.43
1.1
1.3
58.6
290.0
titre
—
7
11
214
460
2.35
25.20
1.1
1.3
190.0
220.6
titre
0.19
39
77
110
162
3.42
25.00
2.8
1.8
7.4
7.4
ph
0.01
27
46
85
103
4.15
24.81
1.3
1.2
—
—
—
0
0
213
461
2.33
24.73
1.3
1.2
0.4
1.4
u/ml
1.60
78
156
177
353
2.53
24.33
1.3
1.7
5.2
7.3
ug/l
2.65
154
318
166
322
2.60
24.08
1.8
1.5
21.7
28.5
umol/l
1.88
158
313
235
543
2.18
23.54
1.1
1.1
—
—
—
0
0
76
88
4.35
23.39
2.7
2.4
—
—
—
0
0
99
142
3.51
23.37
3.1
2.0
9.5
8.9
mmol/l
0.48
75
105
146
270
2.72
23.15
2.0
1.5
3.9
2.9
mg/l
1.65
140
258
2345
9444
1.27
22.65
1.2
1.2
—
—
—
0
0
87
116
3.77
22.63
1.3
1.2
—
—
—
0
0
50
40
6.28
21.89
5.1
7.1
2.3
1.8
mg/l
0.73
40
31
2527
15428
0.80
21.78
1.3
1.3
—
—
—
0
0
379
1081
1.77
21.12
4.1
2.5
—
—
—
0
0
197
444
2.24
20.98
1.1
1.1
—
—
—
0
0
663
2201
1.53
20.53
1.2
1.3
—
—
—
0
0
166
350
2.39
20.48
1.1
1.1
—
—
—
0
0
36
20
9.05
20.29
4.8
5.8
—
—
—
0
0
500
1559
1.62
20.21
2.4
2.7
—
—
—
0
0
58
62
4.70
19.51
2.3
1.2
61.8
90.3
ng/l
0.20
33
35
236
591
2.01
19.41
1.1
1.1
—
—
—
0
0
185
421
2.21
19.31
4.6
5.9
11.8
11.3
%
0.64
185
421
256
664
1.95
19.13
1.8
1.7
—
—
—
0
0
161
349
2.32
18.76
3.1
2.6
42.8
38.4
%
1.48
54
110
201
483
2.10
18.42
1.1
1.1
—
—
—
0
0
185
430
2.17
18.40
1.4
1.5
—
—
—
0
0
99
168
2.97
18.29
1.1
1.1
—
—
—
0
0
168
377
2.25
18.15
3.0
3.4
54.1
56.8
%
0.56
106
234
100
173
2.91
17.91
1.0
1.0
—
—
—
0
0
188
446
2.12
17.81
1.0
1.1
—
—
—
0
0
188
447
2.12
17.72
1.1
1.1
—
—
—
0
0
747
2626
1.44
17.52
1.2
1.1
1.7
2.4
u/ml
0.70
338
1213
128
259
2.49
17.26
2.0
2.6
83.4
569.4
ug/l
0.65
116
243
54
61
4.45
17.17
1.6
1.5
—
—
—
0
0
135
282
2.41
17.07
1.5
1.5
2247.9
2351.7
ml
0.23
28
38
102
185
2.77
16.88
1.4
1.2
248.3
280.0
titre
—
6
7
202
505
2.02
16.77
3.1
3.1
—
—
—
0
0
162
375
2.18
16.33
1.1
1.1
388.5
408.1
nmol/l
0.53
152
355
99
181
2.75
16.18
1.3
1.2
57.0
178.7
titre
—
10
15
172
412
2.10
15.97
2.5
2.0
—
—
—
0
0
35
27
6.51
15.83
1.2
1.4
—
—
—
0
0
112
222
2.54
15.78
11.0
4.6
74.0
2880.0
mg/l
1.08
88
144
143
319
2.26
15.73
3.3
3.8
—
—
—
0
0
223
593
1.90
15.61
1.3
1.6
—
—
titre
—
0
0
31
21
7.42
15.42
10.2
6.2
6.0
5.5
mmol/l
0.23
31
21
33
25
6.63
15.14
1.0
1.0
—
—
—
0
0
452
1480
1.54
15.01
1.2
1.1
—
—
—
0
0
61
87
3.53
14.68
1.3
1.5
283.9
377.5
pmol/l
0.69
40
71
126
275
2.31
14.59
1.5
1.3
12.4
10.9
u/l
1.18
120
266
1434
8925
0.79
14.39
1.4
1.3
—
—
—
0
0
68
109
3.14
13.86
1.7
1.9
—
—
—
0
0
207
560
1.86
13.83
1.0
1.0
—
—
—
0
0
139
326
2.15
13.67
1.1
1.1
7.4
17.4
u/ml
1.96
27
63
568
1993
1.44
13.55
1.5
1.5
0.4
0.4
nmol/l
0.28
450
1638
196
526
1.88
13.44
1.3
1.3
—
—
—
0
0
188
498
1.90
13.39
1.8
1.5
6.5
5.4
mmol/l
4.52
137
411
659
2381
1.40
13.38
1.1
1.1
6.0
6.8
u/ml
0.49
357
1385
43
50
4.32
13.32
4.2
2.4
—
—
—
0
0
51
69
3.72
13.19
1.0
1.1
—
—
—
0
0
86
164
2.64
13.12
1.0
1.0
—
—
—
0
0
628
2263
1.40
12.96
1.1
1.1
0.9
1.4
u/ml
1.30
288
1125
2460
10536
1.19
12.92
2.7
2.7
0.7
0.8
ug/l
4.78
1461
6092
96
196
2.46
12.85
2.0
2.5
8.3
10.0
mg/l
1.72
83
171
146
359
2.05
12.79
1.3
1.2
—
—
—
0
0
34
33
5.18
12.68
1.1
1.0
—
—
—
0
0
52
74
3.53
12.60
1.1
1.1
0.7
0.7
umol/24h
0.02
33
42
162
417
1.96
12.56
1.2
1.1
—
—
—
0
0
30
26
5.80
12.39
2.4
1.5
—
—
—
0
0
44
56
3.95
12.30
1.3
1.3
13.6
22.5
nmol/l
1.72
15
18
768
5063
0.75
12.20
1.4
1.5
—
—
—
0
0
153
392
1.97
12.04
2.1
1.7
2.1
2.0
u/field
0.06
84
182
773
5078
0.76
11.97
1.4
1.5
—
—
—
0
0
20
10
10.05
11.97
1.0
1.0
—
—
—
0
0
985
3854
1.29
11.88
2.4
3.5
31.2
46.0
u/ml
2.57
947
3760
76
144
2.65
11.78
6.8
6.9
24.0
25.1
mmol/l
1.24
70
132
45
62
3.65
11.42
1.1
1.1
—
—
—
0
0
209
604
1.74
11.40
2.4
3.5
5.5
4.3
nmol/l
0.27
204
585
796
5171
0.76
11.35
1.5
1.5
—
—
—
0
0
435
1503
1.46
11.32
3.7
2.3
23.5
27.3
mg/l
1.45
277
917
46
65
3.56
11.29
1.6
1.5
534293.1
112506.9
nmol/l
0.35
35
56
57
94
3.05
11.20
1.0
1.1
73.8
83.7
ug/l
0.92
51
78
270
847
1.61
10.90
1.5
1.5
11.8
10.4
mmol/l
0.45
63
23
364
1227
1.50
10.73
2.5
2.6
—
—
—
0
0
434
1516
1.44
10.71
1.1
1.1
2.5
2.9
u/ml
0.37
211
876
40
53
3.79
10.69
1.1
1.2
—
—
—
0
0
67
126
2.67
10.57
2.8
2.5
3.0
2.4
mmol/l
1.09
62
119
122
303
2.03
10.51
1.8
1.4
2.7
2.2
u/field
0.25
89
219
37
47
3.96
10.42
1.2
1.1
—
—
—
0
0
75
151
2.50
10.41
2.5
2.5
—
—
—
0
0
625
2342
1.35
10.26
1.1
1.1
2.2
3.2
u/ml
0.87
172
670
89
196
2.28
10.25
1.7
1.6
7.1
5.6
mmol/24h
0.57
11
23
35
43
4.09
10.25
1.2
1.1
—
—
—
0
0
53
89
2.99
10.15
1.3
1.7
200.6
78.3
mu/l
0.46
43
74
71
141
2.53
10.14
1.9
2.0
96.5
76.2
au/ml
0.19
11
16
45
69
3.28
9.91
2.6
2.6
—
—
—
0
0
221
678
1.64
9.79
3.6
5.6
152.9
84.2
u/ml
0.61
61
230
40
57
3.53
9.75
2.0
1.9
—
—
—
0
0
1462
6132
1.21
9.61
1.6
1.5
—
—
—
0
0
530
1959
1.37
9.52
1.1
1.1
6.3
4.5
u/ml
0.50
222
866
332
1128
1.48
9.48
1.2
1.3
—
—
—
0
0
75
159
2.37
9.42
1.3
1.5
—
—
—
0
0
85
191
2.24
9.40
1.8
1.2
—
—
—
0
0
156
443
1.77
9.13
1.4
1.3
71.6
73.4
%
0.76
147
424
578
2181
1.34
9.11
2.4
2.6
5.4
6.7
umol/l
1.62
428
1618
173
508
1.71
9.04
1.2
1.2
—
—
—
0
0
93
221
2.12
9.03
1.7
1.5
—
—
—
0
0
220
690
1.61
8.98
14.4
13.1
768.8
840.5
nmol/l
1.54
211
665
49
85
2.90
8.95
1.4
1.5
—
—
—
0
0
58
111
2.63
8.93
1.3
1.1
—
—
—
0
0
183
548
1.68
8.92
1.1
1.1
7.0
7.1
iu/ml
0.03
46
162
47
80
2.95
8.86
1.8
1.4
—
—
—
0
0
33
44
3.77
8.80
2.2
1.4
7.9
6.1
mmol/l
0.89
20
26
24
24
5.02
8.76
1.3
1.5
38.8
42.4
umol/l
0.30
24
24
226
719
1.58
8.72
19.7
19.6
1439.0
2710.3
nmol/l
0.47
219
687
151
431
1.76
8.72
1.4
1.4
436.9
633.4
mu/l
1.55
142
412
64
131
2.46
8.67
1.2
1.2
—
—
—
0
0
77
172
2.25
8.67
2.2
1.8
—
—
—
0
0
90
215
2.11
8.65
1.7
1.7
—
—
—
0
0
31
40
3.89
8.61
1.1
1.1
1.7
1.5
umol/24h
0.41
31
40
186
569
1.65
8.41
1.2
1.2
—
—
—
0
0
121
326
1.87
8.40
1.4
1.3
—
—
—
0
0
488
1819
1.35
8.38
1.1
1.1
7.8
5.8
u/ml
0.54
214
851
167
499
1.68
8.25
1.5
1.3
32.0
35.7
g/l
2.62
149
452
512
1929
1.34
8.20
1.1
1.1
—
—
—
0
0
18
14
6.46
8.14
1.4
1.6
699.1
366.2
nmol/l
1.01
18
14
421
1540
1.38
8.14
1.1
1.1
0.6
0.6
u/ml
0.01
109
354
222
716
1.56
8.12
1.1
1.1
—
—
—
0
0
45
79
2.86
8.10
3.3
1.8
—
—
—
0
0
509
1927
1.33
7.91
1.1
1.1
—
—
—
0
0
27
34
3.99
7.75
1.2
1.0
—
—
—
0
0
164
497
1.66
7.72
1.3
1.4
—
—
—
0
0
1395
5948
1.19
7.71
1.4
1.4
—
—
—
0
0
16
7
11.48
7.60
1.2
1.4
—
—
—
0
0
56
115
2.45
7.59
1.4
1.3
59.1
58.5
%
0.03
44
100
1006
6069
0.82
7.51
1.4
1.4
—
—
—
0
0
44
80
2.76
7.49
1.3
1.3
—
—
—
0
0
33
50
3.32
7.47
1.2
1.0
—
—
—
0
0
50
98
2.56
7.43
1.0
1.0
—
—
—
0
0
41
72
2.86
7.40
1.3
1.1
185.5
110.7
mg/l
0.20
27
49
79
192
2.07
7.34
1.2
1.2
—
—
—
0
0
124
354
1.76
7.24
1.1
1.0
5.4
13.8
u/ml
1.85
15
36
154
468
1.66
7.21
1.4
1.4
2495.3
4056.3
e6/l
0.49
107
325
136
402
1.70
7.06
1.4
1.2
6.2
5.4
mmol/l
3.90
128
369
21
23
4.59
7.04
1.0
1.4
0.2
0.8
umol/24h
—
10
9
30
45
3.35
6.91
1.1
1.2
—
—
—
0
0
7417
35174
1.08
6.87
2.5
1.9
—
—
—
0
0
152
472
1.62
6.60
1.4
1.3
61.4
72.5
umol/l
1.87
13
53
15
8
9.42
6.59
1.1
1.0
—
—
mmol/l
—
0
0
13
5
13.06
6.56
5.2
4.2
435.2
361.4
umol/l
—
13
5
53
115
2.32
6.47
1.1
1.0
—
—
—
0
0
119
348
1.72
6.46
2.6
3.3
137.3
158.7
au/ml
0.15
25
34
59
135
2.20
6.40
1.2
1.2
—
—
—
0
0
120
353
1.71
6.38
1.2
1.3
—
—
—
0
0
45
91
2.48
6.35
1.6
1.3
32.7
24.2
%
0.89
40
84
63
150
2.11
6.23
1.1
1.1
1.7
7.6
u/ml
0.70
31
76
63
151
2.10
6.13
1.1
1.1
0.1
1.6
u/ml
1.20
37
75
31
52
2.99
6.08
1.4
1.3
—
—
—
0
0
76
197
1.94
6.03
1.4
1.2
—
—
—
0
0
136
421
1.62
6.02
1.1
1.1
2.8
33.1
u/ml
0.89
80
289
23
32
3.61
5.89
2.8
4.0
—
—
—
0
0
29
49
2.97
5.65
5.7
4.2
44.8
39.4
ug/min
0.11
22
31
51
117
2.19
5.55
1.7
1.5
—
—
—
0
0
122
377
1.63
5.48
2.3
2.2
155.4
151.8
nmol/l
0.13
100
322
105
312
1.69
5.46
1.4
1.6
—
—
—
0
0
89
253
1.77
5.39
1.2
1.2
11.8
13.4
u/l
0.53
80
243
26
43
3.04
5.25
2.0
1.5
—
—
—
0
0
443
1752
1.27
5.16
1.5
1.4
114.3
115.2
pmol/l
0.01
429
1712
126
399
1.59
5.16
3.1
4.0
7.6
9.1
mg/l
1.91
101
333
39
82
2.39
5.16
1.1
1.0
—
—
—
0
0
44
98
2.26
5.15
1.5
1.3
3.2
3.4
%
0.04
38
89
34
67
2.55
5.11
2.7
2.1
23.9
23.1
mg/l
—
8
14
129
415
1.56
4.96
1.6
1.5
—
—
—
0
0
487
3024
0.80
4.96
1.2
1.2
—
—
—
0
0
409
1611
1.28
4.94
2.3
1.7
13.1
13.0
%
1.42
403
1583
22
34
3.25
4.92
1.1
1.1
1290.6
42.0
u/l
0.47
17
28
34
69
2.48
4.85
1.2
1.2
25.8
23.5
%
0.14
24
57
4043
18938
1.09
4.84
1.8
1.7
—
—
—
0
0
44
101
2.19
4.83
2.4
6.6
35.1
76.1
u/l
0.66
12
38
13
13
5.02
4.79
2.1
1.7
—
—
—
0
0
10
5
10.04
4.67
1.7
1.0
4.0
2.6
mu/l
—
10
5
54
138
1.97
4.56
1.1
1.1
0.6
0.6
u/ml
0.03
29
74
364
1430
1.28
4.53
1.4
1.5
6.9
6.2
mmol/l
3.98
256
971
22
37
2.99
4.37
3.0
3.8
—
—
—
0
0
129
429
1.51
4.34
1.5
1.4
136531.8
35390.9
e6/l
1.05
79
250
31
64
2.43
4.31
1.0
1.0
0.2
0.2
u/ml
—
10
24
71
203
1.76
4.30
1.1
1.1
—
—
—
0
0
36
80
2.26
4.29
1.8
1.8
14.6
24.1
pmol/l
1.38
30
68
71
204
1.75
4.24
1.1
1.1
—
—
—
0
0
71
204
1.75
4.24
1.1
1.1
—
—
—
0
0
124
414
1.51
4.12
1.5
1.4
—
—
—
0
0
117
386
1.52
4.11
1.5
1.4
—
—
—
0
0
113
371
1.53
4.06
1.1
1.1
—
—
—
0
0
198
1336
0.74
3.99
1.2
1.2
—
—
—
0
0
33
73
2.27
3.99
2.2
2.2
—
—
—
0
0
11
9
6.14
3.99
1.5
1.2
—
—
—
0
0
13
16
4.08
3.90
1.0
1.1
0.1
0.1
u/ml
—
8
11
279
1085
1.29
3.83
3.1
3.5
63.9
101.1
u/ml
0.22
258
972
84
652
0.65
3.75
1.0
1.0
—
—
—
0
0
396
1612
1.24
3.73
1.3
1.2
—
—
—
0
0
23
44
2.63
3.72
1.0
1.2
—
—
—
0
0
17
27
3.16
3.71
1.0
1.1
—
—
—
0
0
13
17
3.84
3.64
1.0
1.1
—
—
—
0
0
93
302
1.55
3.56
1.2
1.2
3.5
15.1
u/ml
2.83
64
221
29
64
2.28
3.56
1.0
1.0
0.1
1.3
u/ml
1.40
23
59
14
20
3.51
3.53
1.1
1.0
—
—
—
0
0
102
339
1.51
3.53
2.4
2.1
—
—
—
0
0
22
43
2.57
3.44
1.0
1.0
0.1
0.9
u/ml
—
6
24
28
62
2.27
3.42
1.1
1.1
1.4
2.2
mmol/l
2.20
16
38
200
1310
0.76
3.33
3.8
3.3
26.4
36.3
u/ml
0.80
194
1263
9
8
5.65
3.19
1.2
1.0
2.2
1.9
mmol/24h
—
9
8
9
8
5.65
3.19
1.0
1.0
—
—
—
0
0
1363
7542
0.90
3.19
1.5
1.4
—
—
—
0
0
17
30
2.85
3.18
1.2
1.2
—
—
—
0
0
17
30
2.85
3.18
1.2
1.0
—
—
—
0
0
8
6
6.69
3.17
1.1
1.0
—
—
—
0
0
8
6
6.69
3.17
1.1
1.0
—
—
—
0
0
18
33
2.74
3.17
1.1
1.1
—
—
—
0
0
91
303
1.51
3.16
2.3
2.0
—
—
—
0
0
52
151
1.73
3.10
1.4
1.8
—
—
—
0
0
41
111
1.86
3.05
1.1
1.1
—
—
—
0
0
215
837
1.29
3.02
1.5
1.3
180.7
68.7
pmol/l
0.53
87
162
23
50
2.31
2.96
1.0
1.0
1.1
0.9
mmol/l
0.13
14
36
145
535
1.36
2.95
1.4
1.5
5.4
5.1
mmol/l
3.83
135
518
40
110
1.83
2.86
1.1
1.1
3.6
11.3
u/ml
3.45
28
72
10
13
3.86
2.83
1.1
1.1
242.0
143.4
ug/l
—
5
8
320
1945
0.82
2.83
1.3
1.3
—
—
—
0
0
13
21
3.11
2.80
5.4
1.5
—
—
—
0
0
13
21
3.11
2.80
1.1
1.5
—
—
—
0
0
14
24
2.93
2.76
1.1
1.0
0.1
0.1
u/ml
—
7
12
9
10
4.52
2.75
1.0
1.0
—
—
—
0
0
82
596
0.69
2.74
6.6
6.4
—
—
—
0
0
82
596
0.69
2.74
3.3
3.2
—
—
—
0
0
36
99
1.83
2.60
1.9
1.2
12.6
13.3
g/l
0.13
24
69
10
14
3.59
2.60
1.3
1.0
—
—
—
0
0
10
14
3.59
2.60
1.5
1.0
75.0
32.2
mg/l
—
10
14
16
31
2.59
2.59
3.0
2.1
—
—
—
0
0
246
999
1.24
2.51
3.3
4.1
119.1
1120.7
u/ml
1.85
230
915
32
86
1.87
2.49
1.0
1.1
19.8
17.1
u/ml
0.07
26
72
26
65
2.01
2.46
3.3
2.4
—
—
—
0
0
16
32
2.51
2.45
1.8
1.0
—
—
—
0
0
15
29
2.60
2.45
1.5
1.4
—
—
—
0
0
54
172
1.58
2.36
2.5
1.5
895.3
1239.0
e6/l
0.41
41
111
12
21
2.87
2.31
3.7
3.1
4.6
4.5
mmol/l
0.29
12
21
15
30
2.51
2.31
1.0
1.0
0.1
0.3
u/ml
—
8
18
9
13
3.48
2.22
3.1
1.3
—
—
—
0
0
26
68
1.92
2.21
1.1
1.1
4.4
2.3
u/ml
0.30
14
50
22
54
2.05
2.21
5.1
2.8
2.3
1.6
mg/l
0.23
15
36
10
16
3.14
2.20
1.1
1.3
—
—
—
0
0
33
94
1.76
2.18
1.1
1.2
62.2
383.4
ug/l
1.49
15
51
55
409
0.67
2.16
1.1
1.1
—
—
—
0
0
12
22
2.74
2.15
1.1
1.0
0.1
0.1
u/ml
—
5
9
18
41
2.20
2.15
1.1
1.0
0.1
1.1
u/ml
—
7
25
54
177
1.53
2.13
1.1
1.1
9.9
8.7
u/ml
0.08
39
152
6
6
5.02
2.11
2.0
2.0
—
—
—
0
0
6
6
5.02
2.11
1.0
1.0
—
—
—
0
0
115
436
1.33
2.07
5.5
7.9
—
—
—
0
0
33
96
1.73
2.05
1.3
1.1
7.4
5.2
mmol/l
—
5
21
56
190
1.48
1.92
1.1
1.1
—
—
—
0
0
15
34
2.21
1.83
1.8
1.0
—
—
—
0
0
5
5
5.02
1.82
5.4
1.8
136.8
139.6
mmol/l
—
5
5
8
13
3.09
1.82
2.4
1.2
—
—
—
0
0
67
240
1.40
1.76
1.3
1.1
—
—
—
0
0
35
109
1.61
1.75
2.6
3.6
—
—
—
0
0
12
25
2.41
1.74
1.3
1.3
—
—
—
0
0
42
137
1.54
1.74
2.0
1.6
—
—
—
0
0
22
60
1.84
1.71
1.0
1.1
—
—
—
0
0
45
150
1.51
1.70
2.5
1.5
2972.6
5421.0
e6/l
0.57
26
74
40
131
1.53
1.65
7.3
5.8
—
—
—
0
0
5
6
4.18
1.62
1.0
1.0
—
—
—
0
0
43
144
1.50
1.61
2.1
1.5
—
—
—
0
0
94
607
0.78
1.59
1.3
1.3
—
—
—
0
0
37
120
1.55
1.59
1.0
1.0
0.8
2.4
u/ml
0.80
25
80
1250
5861
1.07
1.58
3.6
4.9
11.4
35.4
ug/l
2.40
990
4541
75
280
1.35
1.57
2.5
2.3
170.5
105.9
ng/l
0.88
59
183
5
7
3.59
1.44
1.0
1.4
261.8
324.0
nmol/l
—
5
7
25
76
1.65
1.41
9.6
7.8
—
—
—
0
0
35
116
1.52
1.40
6.2
3.8
—
—
—
0
0
73
279
1.31
1.35
1.2
1.4
16.4
5.1
u/ml
0.44
12
69
9
20
2.26
1.34
4.8
5.5
0.2
0.2
mmol/l
—
9
20
21
62
1.70
1.32
3.1
1.6
0.8
0.6
u/field
0.26
21
62
32
106
1.52
1.30
1.7
1.2
24.9
28.1
g/l
0.42
21
81
15
40
1.88
1.28
1.1
1.0
—
—
—
0
0
8
17
2.36
1.26
1.3
1.4
220.1
303.1
nmol/l
—
8
17
206
889
1.16
1.26
1.1
1.1
3.9
3.1
u/ml
0.11
80
317
189
810
1.17
1.26
1.1
1.1
0.2
1.2
u/ml
1.06
35
131
148
883
0.84
1.25
1.2
1.1
—
—
—
0
0
203
876
1.16
1.25
1.1
1.1
3.5
6.9
u/ml
0.51
64
276
21
64
1.65
1.20
1.0
1.1
—
—
—
0
0
14
38
1.85
1.15
1.1
1.1
—
—
—
0
0
12
31
1.94
1.13
1.0
1.0
0.0
0.3
u/ml
—
6
13
7
15
2.34
1.11
1.0
1.1
—
—
—
0
0
9
21
2.15
1.10
1.0
1.0
—
—
—
0
0
168
978
0.86
1.09
1.5
1.3
—
—
—
0
0
66
258
1.28
1.09
1.5
1.3
—
—
—
0
0
5
10
2.51
1.05
1.2
1.1
—
—
—
0
0
7
16
2.20
1.05
1.1
1.3
112.5
134.9
mmol/24h
—
7
16
9
23
1.96
1.03
1.0
1.0
—
—
—
0
0
13
36
1.81
1.03
1.1
1.1
—
—
—
0
0
348
1581
1.11
1.02
1.6
1.6
7.7
7.2
mmol/l
3.23
204
915
26
89
1.47
0.96
1.2
1.1
28.2
19.9
u/ml
—
6
13
10
26
1.93
0.94
1.0
1.0
0.1
0.3
u/ml
—
5
11
10
26
1.93
0.94
1.1
1.3
1.6
1.4
%
—
10
26
28
98
1.43
0.94
1.5
1.6
—
—
—
0
0
32
115
1.40
0.93
1.0
1.0
0.3
1.3
u/ml
2.77
15
84
461
2140
1.08
0.88
3.2
4.1
6035.5
1484.0
u/ml
0.37
390
1866
127
733
0.87
0.80
1.2
1.2
1.5
1.5
g/l
—
5
18
9
25
1.81
0.79
1.0
1.0
—
—
—
0
0
9
25
1.81
0.79
1.3
1.2
—
—
—
0
0
141
619
1.14
0.78
1.3
1.3
—
—
—
0
0
5
11
2.28
0.78
1.0
1.1
—
—
—
0
0
7
18
1.95
0.77
1.1
1.0
—
—
—
0
0
15
49
1.54
0.71
1.6
1.3
311.6
306.0
umol/24h
0.05
15
49
5
13
1.93
0.69
1.2
1.2
—
—
—
0
0
43
173
1.25
0.65
1.2
1.3
—
—
—
0
0
5
14
1.79
0.64
1.4
1.1
—
—
—
0
0
8
24
1.67
0.64
1.0
1.0
—
—
—
0
0
8
24
1.67
0.64
1.0
1.0
—
—
—
0
0
8
25
1.61
0.62
1.0
1.0
—
—
—
0
0
8
25
1.61
0.62
1.0
1.0
—
—
—
0
0
8
25
1.61
0.62
1.0
1.0
—
—
—
0
0
14
47
1.50
0.61
1.6
1.3
7.3
19.0
%
—
7
30
121
542
1.12
0.55
1.3
1.4
—
—
—
0
0
12
41
1.47
0.49
2.2
2.2
—
—
—
0
0
151
692
1.10
0.48
1.0
1.0
—
—
—
0
0
13
46
1.42
0.46
1.1
1.2
—
—
—
0
0
31
127
1.23
0.44
5.6
2.7
8.4
4.3
%
0.66
12
36
61
268
1.14
0.41
1.1
1.0
20.2
19.8
mmol/l
0.48
53
260
15
56
1.34
0.41
1.2
1.2
—
—
—
0
0
291
1542
0.95
0.39
1.6
1.5
—
—
—
0
0
6
22
1.37
0.35
1.2
1.2
—
—
—
0
0
111
601
0.93
0.31
2.6
3.2
—
—
—
0
0
14
55
1.28
0.29
3.5
3.1
—
—
—
0
0
12
46
1.31
0.29
1.2
1.2
—
—
—
0
0
30
129
1.17
0.29
6.1
8.4
—
—
—
0
0
11
43
1.28
0.24
6.7
7.8
—
—
—
0
0
34
151
1.13
0.23
1.1
2.1
1.3
3.8
ug/l
0.89
11
100
0
6
0.00
0.22
0.0
1.7
—
—
—
0
0
19
81
1.18
0.21
1.2
1.1
—
—
—
0
0
29
129
1.13
0.20
2.6
2.7
—
—
—
0
0
145
751
0.97
0.12
1.3
1.2
—
—
—
0
0
53
252
1.06
0.11
1.0
1.0
-0.6
-2.2
mmol/l
1.22
12
62
53
253
1.05
0.10
1.0
1.0
6.9
7.3
kpa
1.10
45
225
53
253
1.05
0.10
1.0
1.0
—
—
—
0
0
52
249
1.05
0.09
1.0
1.0
3.6
3.5
kpa
0.14
44
219
346
1713
1.01
0.08
1.8
1.8
—
—
—
0
0
11
50
1.10
0.05
1.0
1.2
—
—
—
0
0
507
2560
0.99
0.04
1.3
1.3
4.1
4.1
ug/l
0.00
475
2389
210
1045
1.01
0.03
1.4
1.3
29.6
34.0
nmol/l
1.57
187
985
28
143
0.98
0.00
1.3
1.2
—
—
—
0
0
15
75
1.00
0.00
1.1
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
5
26
0.97
0.00
1.4
1.3
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: NEURODIS – Neurological diseases, wide definition

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).