Risteys ·

OMOP concept ID	Test name	Measurement unit (harmonized unit)	N people	N records	Missing measurement value	Harmonized value distribution	Test outcome NA N A AA L LL H HH
3017312	ts-igh-d	— (—)	195	217	100.00%	Distribution not available
3017312	b-igh-d	— (—)	16	16	100.00%	Distribution not available

LabWAS

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

Primary_lymphoid and hematopoietic malignant neoplasms

152

140.15

303.08

1.1

1.0

—

Primary_lymphoid and hematopoietic malignant neoplasms

152

96.40

292.32

1.1

—

Enlarged lymph nodes

70.85

167.69

1.2

1.0

—

Non-follicular lymphoma

80.07

161.20

1.1

1.0

—

Non-Hodgkin lymphoma, all, excluding all cancers (controls excluding all cancers)

130

221.95

126.35

1.1

1.0

—

Secondary uncertain malignant neoplasm, excluding all cancers (controls excluding all cancers)

41.49

119.62

1.1

1.0

—

Non-follicular lymphoma, hilmo, excluding all cancers

176.14

82.50

1.1

1.0

—

Malignant neoplasm

15.01

73.52

1.2

1.0

—

Malignant neoplasm, excluding all cancers (controls excluding all cancers)

15.49

72.68

1.1

1.0

—

Malignant neoplasm, wide definition for exclusion

15.49

72.67

1.1

1.0

—

Malignant neoplasm, wide definition for exclusion, excluding all cancers (controls excluding all cancers)

15.49

72.67

1.1

1.0

—

Secondary uncertain malignant neoplasm

84.64

67.12

1.1

1.0

—

Secondary and unspecified malignant neoplasm of lymph nodes, excluding all cancers (controls excluding all cancers)

119.74

65.97

1.1

1.0

—

Secondary and unspecified malignant neoplasm of lymph nodes

102.24

64.10

1.1

1.0

—

Fever of other and unknown origin

11.56

56.99

1.2

1.1

—

Any event in cancer register

10.27

55.61

1.2

1.0

—

General symptoms and signs

7.07

40.93

1.1

1.0

—

Neoplasms

13.79

39.23

1.2

1.0

—

Marginal zone B-cell lymphoma, excluding all cancers (controls excluding all cancers)

+∞

33.70

1.1

0.0

—

Diffuse large B-cell lymphoma

63.12

32.15

1.1

1.0

—

Malignant neoplasm of skin, excluding all cancers (controls excluding all cancers)

14.05

31.97

1.2

1.0

—

Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

124

4.63

30.62

1.1

—

Other medical care

6.86

30.32

1.2

1.1

—

ILD medications: prednisolone, methylprednisolone, prednisone

101

4.53

27.51

1.1

—

Other malignant neoplasms of skin (=non-melanoma skin cancer), excluding all cancers (controls excluding all cancers)

13.73

27.40

1.2

1.0

—

Marginal zone B-cell lymphoma

+∞

26.46

1.1

0.0

—

First line medication for Crohn's disease

4.54

26.46

1.1

—

ILD medications

101

4.35

25.64

1.1

—

Benign neoplasms

9.60

24.49

1.1

1.0

—

Other diseases of blood and blood-forming organs, wide

8.77

22.39

1.2

1.1

—

Mature T/NK-cell lymphomas, hilmo, excluding all cancers

+∞

22.05

1.3

0.0

—

Follicular lymphoma, hilmo

44.02

21.44

1.1

1.0

—

Localized swelling, mass and lump of skin and subcutaneous tissue

6.61

20.81

1.1

—

Bacterial infection, other or unspecified

4.95

20.75

1.2

1.1

—

Malignant neoplasm of digestive organs, excluding all cancers (controls excluding all cancers)

12.82

20.58

1.1

1.0

—

Symptoms and signs involving the skin and subcutaneous tissue

128

4.12

19.78

1.2

1.1

—

Basal cell carcinoma, excluding all cancers (controls excluding all cancers)

11.51

19.61

1.1

1.0

—

Basal cell carcinoma, including avohilmo, excluding all cancers (controls excluding all cancers)

11.48

19.55

1.1

1.0

—

Other bacterial diseases

124

3.68

18.88

1.1

—

Hodgkin lymphoma

+∞

18.80

1.2

0.0

—

Any gastric operation

5.70

17.01

1.0

1.1

—

GASTRO-related operations

5.70

17.01

1.0

1.1

—

Anaemias

12.71

16.94

1.0

—

Melanocytic naevi

12.32

16.02

1.1

1.0

—

Purpura and other haemorrhagic conditions

9.08

15.54

1.2

1.0

—

Oxycodone

4.64

14.64

1.1

1.2

—

Chronic lymphocytic leukaemia and small lyphocytis leukaemia, excluding all cancers (controls excluding all cancers)

+∞

14.62

1.1

0.0

—

Chronic lymphocytic leukaemia, helper endpoint

+∞

14.62

1.1

0.0

—

Inflammatory bowel disease treatment related agents

125

3.09

14.17

1.1

—

Coagulation defects, purpura and other haemorrhagic conditions

7.42

13.96

1.2

1.1

—

Oral corticosteroids

124

3.12

13.87

1.2

1.1

—

Abnormal findings on diagnostic imaging and in function studies, without diagnosis

118

3.54

13.40

1.1

—

Thrombocytopenia, unspecified

11.87

12.64

1.1

1.0

—

Abnormal findings on diagnostic imaging of lung

3.74

12.46

1.2

1.1

—

Lymphoid leukaemia

23.02

11.56

1.1

1.0

—

Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue

+∞

11.53

1.3

0.0

—

Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue

+∞

11.53

1.3

0.0

—

COPD/asthma/ILD related pneumonia or pneumonia derived septicaemia

117

2.95

11.05

1.2

1.1

—

117

2.95

11.05

1.2

1.1

—

Transplanted organ and tissue status

7.92

11.00

1.3

1.1

—

Benign neoplasm of colon, rectum, anus and anal canal

7.57

10.98

1.1

1.0

—

Influenza and pneumonia

142

2.73

10.56

1.2

1.1

—

Certain disorders involving the immune mechanism

5.77

10.52

1.1

—

Aplastic and other anaemias

3.82

10.43

1.1

—

Benign lipomatous neoplasm

11.01

10.16

1.0

—

Pneumonias (Asthma/COPD co-morbidities)

143

2.71

10.07

1.2

1.1

—

All pneumoniae

144

2.68

9.86

1.2

1.1

—

Persons encountering health services for specific procedures and health care

136

2.64

9.63

1.2

1.1

—

Other benign neoplasms of skin

7.97

9.50

1.2

1.0

—

Hepatomegaly and splenomegaly, not elsewhere classified

+∞

9.41

1.0

0.0

—

Pneumonia (excl. viral and due to other infectious organisms not elsewhere classified)

143

2.65

9.38

1.2

1.1

—

Pneumonia, organism unspecified

132

2.74

9.29

1.2

1.1

—

ILD medications: immunosuppressive drugs

3.38

8.81

1.1

—

In situ neoplasms

7.30

8.74

1.2

1.0

—

Other anaemias

3.56

8.60

1.1

—

Dialysis, with operation codes

6.38

8.52

1.5

1.1

—

Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified

11.29

8.43

1.1

1.0

—

Other diseases of intestine

7.51

8.41

1.2

1.0

—

Malignant immunoproliferative diseases

+∞

8.37

1.5

0.0

—

Malignant immunoproliferative diseases

+∞

8.37

1.5

0.0

—

Acquired haemolytic anaemia

+∞

8.34

1.0

0.0

—

Other septicaemia

4.00

8.00

1.3

1.1

—

Agranulocytosis

7.07

7.99

1.0

—

Other and unspecified anaemias

3.44

7.92

1.1

—

Malaise and fatigue

4.17

7.31

1.0

1.1

—

Other malignant neoplasms of skin (=non-melanoma skin cancer)

2.93

7.14

1.2

1.1

—

Septicaemia

3.57

7.13

1.3

1.1

—

Malignant neoplasm of respiratory system and intrathoracic organs, excluding all cancers (controls excluding all cancers)

8.39

7.03

1.2

1.0

—

Benign neoplasm: Colon

6.23

6.98

1.2

1.0

—

Malignant neoplasm of skin

104

2.68

6.76

1.2

1.1

—

Malignant neoplasm of head and neck, excluding all cancers (controls excluding all cancers)

16.70

6.74

1.3

1.0

—

Zoster [herpes zoster]

5.01

6.70

1.2

1.0

—

Benign neoplasms

115

2.38

6.54

1.1

—

Symptoms and signs involving the digestive system and abdomen

112

2.33

6.42

1.2

1.1

—

Certain infectious and parasitic diseases

2.43

6.33

1.1

—

Nephropathy related operations

5.47

6.28

1.4

1.1

—

Other autoimmune haemolytic anaemias

+∞

6.26

1.0

0.0

—

Other skin changes

5.80

6.10

1.4

1.0

—

Immunodeficiencies

15.06

5.90

1.1

1.0

—

Other disorders of skin and subcutaneous tissue, not elsewhere classified

5.01

5.74

1.1

1.0

—

Viral infections characterized by skin and mucous membrane lesions

2.96

5.66

1.1

—

L04AD Calcineurin inhibitors

5.89

5.62

1.1

—

Malignant neoplasm of eye, brain and central nervous system

16.07

5.41

1.3

1.0

—

Other disorders of white blood cells

16.06

5.41

1.0

—

Mantle cell lymphoma, excluding all cancers (controls excluding all cancers)

+∞

5.22

1.2

0.0

—

Malignant neoplasm of small intestine, excluding all cancers (controls excluding all cancers)

+∞

5.21

1.2

0.0

—

Rare circulating lymphoid malignancy, excluding all cancers (controls excluding all cancers)

+∞

5.21

1.2

0.0

—

Malignant neoplasm of stomach

13.38

5.08

1.0

—

Other noninfective gastroenteritis and colitis

3.75

5.07

1.3

1.1

—

Dental caries

3.72

5.00

1.1

1.2

—

Explicit Sepsis

2.79

4.88

1.3

1.1

—

Migraine without aura

4.29

4.82

1.1

—

Chronic gastritis

3.11

4.62

1.1

—

Benign neoplasm of major salivary glands

14.02

4.57

1.1

1.0

—

Other diseases of jaws

10.02

4.52

1.0

—

Syncope and collapse

3.50

4.48

1.1

—

Other viral diseases, not elsewhere classified

3.99

4.41

1.2

1.1

—

Noninfective enteritis and colitis

2.61

4.37

1.2

1.1

—

COPD differential diagnosis

2.33

4.33

1.1

—

ILD differential diagnosis

2.33

4.33

1.1

—

Gingivitis and periodontal diseases

103

2.11

4.29

1.1

—

Excluding asthma or asthma-COPD overlap

2.30

4.22

1.1

—

Melanocytic naevi

3.14

4.20

1.1

—

Abdominal and pelvic pain

112

2.02

4.12

1.1

—

Other disorders of the genitourinary system

4.35

4.08

1.1

1.0

—

Other viral diseases

3.18

4.03

1.1

1.2

—

Leiomyoma of uterus

4.23

3.92

1.0

—

Other pulmonary diagnosis

2.23

3.86

1.2

1.1

—

Budesonide

6.01

3.81

1.1

1.0

—

Autoimmune diseases excluding thyroid diseases

137

1.90

3.79

1.2

1.1

—

Benign neoplasm: Rectum

8.76

3.77

1.1

1.0

—

Benign neoplasm: Rectum, anus and anal canal

8.76

3.77

1.1

1.0

—

Personal history of malignant neoplasm

12.04

3.76

1.0

—

Malignant neoplasm of mesothelium and soft tissue

12.04

3.76

1.2

1.0

—

Medical observation and evaluation for suspected diseases and conditions

2.22

3.71

1.1

—

Infections, IBD-co-morbidities

4.01

3.71

1.1

—

Codes for special purposes

2.56

3.70

1.1

—

Autoimmune diseases excluding thyroid diseases, strict definition

135

1.90

3.69

1.2

1.1

—

Nausea and vomiting

3.47

3.66

1.1

—

Bacterial pneumoniae

2.59

3.50

1.1

1.0

—

Malignant neoplasm of head and neck

6.16

3.50

1.4

1.0

—

Benign neoplasm of other and unspecified endocrine glands

10.01

3.49

1.0

—

Squamous cell neoplasms and carcinomas of the skin, excluding all cancers (controls excluding all cancers)

10.00

3.49

1.0

—

Oedema, not elsewhere classified

3.83

3.49

1.2

1.0

—

Asthma, unspecified (mode), excluding more controls

2.53

3.45

1.0

1.1

—

Other diseases of hard tissues of teeth

2.17

3.45

1.0

1.2

—

Covid-19 confirmed case

2.98

3.40

1.1

—

Bacterial pneumonia, not elsewhere classified

2.61

3.38

1.1

1.0

—

Asthma (mode)

2.18

3.34

1.0

1.1

—

Persons encountering health services for other counselling and medical advice, not elsewhere classified

148

1.81

3.33

1.1

—

Asthma, unspecified (mode)

2.48

3.32

1.0

1.1

—

Asthma, excluding more controls

2.18

3.30

1.0

1.1

—

Noninfectious colitis NAS

4.74

3.23

1.3

1.0

—

Diaphragmatic hernia

2.44

3.20

1.0

1.1

—

Provisional assignment of new diseases of uncertain etiology

2.44

3.20

1.1

—

Implicit viral Sepsis

3.34

3.19

1.1

—

Gastrointestinal diseases

2.40

3.18

1.1

—

Bacterial pneumonia (organism specified)

2.33

3.17

1.1

—

Asthma

2.13

3.16

1.0

1.1

—

Acute upper respiratory infections of multiple and unspecified sites

116

2.00

3.13

1.1

—

Other extrapyramidal and movement disorders in other diseases

2.96

3.13

1.2

1.0

—

Chronic rhinitis, nasopharyngitis and pharyngitis

2.62

3.12

1.1

—

COPD/asthma/ILD related infections

117

1.84

3.12

1.2

1.1

—

COPD/asthma related infections

117

1.84

3.12

1.2

1.1

—

Malignant neoplasm of bronchus and lung, excluding all cancers (controls excluding all cancers)

6.49

3.12

1.1

1.0

—

malignant neoplasm of male genital organs, excluding all cancers (controls excluding all cancers)

7.13

3.07

1.1

1.0

—

Viral Sepsis

3.24

3.05

1.1

—

Other symptoms and signs involving the digestive system and abdomen

5.00

3.05

1.3

1.1

—

Parasetamol

1.97

3.02

1.0

1.1

—

Benign neoplasm of eye and adnexa

10.01

2.98

1.2

1.0

—

Benign neoplasm: Skin of other and unspecified parts of face

10.01

2.98

1.0

—

Examination and observation for other reasons

2.14

2.96

1.0

1.1

—

Gastroduodenal ulcer

2.63

2.94

1.0

1.1

—

Gastric ulcer

3.15

2.92

1.0

1.1

—

Persons encountering health services in other circumstances, wide

148

1.72

2.90

1.2

1.1

—

Acute pharyngitis

4.68

2.90

1.4

1.0

—

Any reimbursement code in KELA

2.44

2.88

1.1

—

ILD, hospital admissions 1, main diag only

4.10

2.88

1.1

1.0

—

Malignant melanoma, excluding all cancers (controls excluding all cancers)

6.67

2.86

1.0

—

Other disorders of lacrimal gland

2.50

2.86

1.2

1.1

—

Asthma and allergy

6.59

2.84

1.0

—

malignant neoplasm of female genital organs, excluding all cancers (controls excluding all cancers)

6.55

2.83

1.0

—

Bell's palsy

4.45

2.79

1.1

—

Inflammatory bowel disease

2.54

2.78

1.3

1.1

—

Dentinal caries

3.04

2.78

1.0

1.2

—

Sarcoidosis

3.92

2.77

1.1

—

Pain, not elsewhere classified

3.91

2.77

1.1

1.0

—

Basal cell carcinoma

103

2.01

2.73

1.1

—

Secondary malignant neoplasm of other and unspecified sites, excluding all cancers (controls excluding all cancers)

6.00

2.69

1.0

—

Conjunctivitis (acute, non atopic)

2.70

2.69

1.4

1.1

—

Diseases of salivary glands

3.75

2.67

1.1

1.0

—

Used for control exclusion in common control thyroid runs

126

1.73

2.62

1.1

—

Rash and other nonspecific skin eruption

4.67

2.59

1.0

—

Basal cell carcinoma, including avohilmo

104

1.97

2.58

1.1

—

DVT of lower extremities and pulmonary embolism

2.14

2.58

1.2

1.1

—

Erysipelas

2.11

2.55

1.1

—

Respiratory diseases principally affecting the interstitium, IBD co-morbidites

4.21

2.55

1.0

1.1

—

Stomatitis and related lesions

7.15

2.55

1.0

—

Dermatitis

128

1.95

2.54

1.1

—

Other and unspecified dermatitis

101

2.08

2.52

1.1

—

Asthma and allergy, excluding more controls

5.39

2.52

1.0

—

Deposits [accretions] on teeth

6.90

2.49

1.0

—

ILD, hospital admissions

3.47

2.48

1.1

1.0

—

Other interstitial pulmonary diseases

3.47

2.48

1.1

1.0

—

Interstitial lung disease endpoints

3.47

2.48

1.1

1.0

—

Interstitial lung disease

3.47

2.48

1.1

1.0

—

Benign neoplasm: salivary glands, exclude unknown (D119)

4.38

2.47

1.1

1.0

—

Migraine without aura and triptan purchases

3.81

2.46

1.0

—

Renal tubulo-interstitial diseases

148

1.76

2.43

1.1

—

Autoimmune diseases related-to ILD

165

1.76

2.40

1.3

1.1

—

Persons with potential health hazards related to family and personal history and certain conditions influencing health status

151

1.71

2.40

1.1

—

Other and unspecified disorders of skin and subcutaneous tissue

5.01

2.40

1.2

1.0

—

Other inflammatory liver diseases

5.01

2.40

1.0

—

Viral warts

5.01

2.40

1.2

1.0

—

Inflammatory diseases of the central nervous system

5.01

2.40

1.0

—

L04AX Other immunosuppressants

124

1.94

2.39

1.1

—

Ovarian dysfunction

6.26

2.37

1.0

—

Implicit Sepsis

129

1.81

2.34

1.0

1.1

—

Convulsions, not elsewhere classified

4.07

2.33

1.0

—

Condition for Implicit Sepsis (Organ dysfunction codes)

137

1.75

2.30

1.0

1.1

—

Cardiovascular diseases (excluding rheumatic etc)

1.95

2.29

1.1

—

Other diseases of intestines

139

1.67

2.28

1.3

1.1

—

Bronchitis

163

1.65

2.28

1.1

—

Headache

2.32

2.26

1.1

1.0

—

Other disorders of eye and adnexa

3.89

2.25

1.0

1.1

—

Second line medication for Crohn's disease

127

1.89

2.25

1.1

—

Diseases of oral cavity, salivary glands and jaws

103

1.74

2.24

1.1

—

Migraine

2.13

2.24

1.1

—

Acute alcohol intoxication

0.00

2.23

0.0

1.2

—

Chronic periodontitis

3.11

2.22

1.2

—

Multiple myeloma and malignant plasma cell neoplasms

5.57

2.21

1.2

1.0

—

Drug-induced neutropenia

5.56

2.21

1.0

—

Other Crohn's disease

5.56

2.21

1.2

1.1

—

ILD, hospital admission 2, with pulmonary infections

5.56

2.21

1.2

1.0

—

Malignant melanoma of skin, excluding all cancers (controls excluding all cancers)

5.56

2.21

1.0

—

Benign neoplasm of other and ill-defined parts of digestive system

5.56

2.21

1.0

—

Hypertensive diseases (excluding secondary)

1.97

2.17

1.1

—

Acute tubulo-interstitial nephritis

120

1.85

2.16

1.2

1.1

—

Collagenous colitis

4.29

2.15

1.2

1.0

—

Squamous cell neoplasms and carcinomas of the skin

4.29

2.15

1.0

—

Benign neoplasm of major salivary glands

3.69

2.15

1.1

1.0

—

Other respiratory diseases principally affecting the interstitium

3.00

2.14

1.1

1.0

—

Asthma-related pneumonia

2.16

2.13

1.0

1.1

—

Diseases of oesophagus, stomach and duodenum

149

1.63

2.12

1.0

1.1

—

Ulcerative colitis

2.56

2.09

1.4

1.1

—

Intestinal infectious diseases

164

1.66

2.08

1.2

1.1

—

Asthma, hospital admissions 3, pneumonia

2.13

2.07

1.0

1.1

—

Asthma-related pneumonia or sepsis

2.13

2.07

1.0

1.1

—

Carcinoma in situ of skin of other and unspecified parts of face

5.01

2.07

1.0

—

Benign neoplasm: Colon, unspecified

4.98

2.06

1.2

1.0

—

Diabetes mellitus

175

0.48

2.06

1.1

—

Restless leg syndrome

3.50

2.05

1.1

—

Crohn disease

3.50

2.05

1.1

—

Diabetes, varying definitions

175

0.48

2.05

1.1

—

Implicit bacterial Sepsis

2.08

2.04

1.1

—

Allergic asthma (mode)

2.85

2.02

1.0

—

Allergic asthma (mode), excluding more controls

2.85

2.02

1.0

—

Disorders of eyelid, lacrimal system and orbit

155

1.67

2.02

1.1

—

143

1.59

2.01

1.3

1.1

—

Other inflammation of eyelid

3.34

1.96

1.0

—

Hypothyroidism, levothyroxine purchases

3.66

1.96

1.3

1.0

—

Hypothyroidism and >3 levothyroxin purchases

3.66

1.96

1.3

1.0

—

Hypothyroidism (congenital or acquired)

3.66

1.96

1.3

1.0

—

Diagnoses used for exclusion with ILD

2.35

1.94

1.1

—

Nonspecific lymphadenitis

4.55

1.94

1.2

1.0

—

Benign lipomatous neoplasm of other sites/unspecified

4.55

1.94

1.0

—

Left ventricular outflow tract obstruction (LVOTO), broad definition

3.75

1.93

1.0

1.2

—

Viral pneumonia

3.75

1.93

1.0

1.1

—

2.02

1.93

1.1

—

Gonarthrosis, primary, with knee surgery

129

0.38

1.91

1.2

1.1

—

Disorders of lacrimal system

2.00

1.89

1.2

1.1

—

Malignant neoplasm of prostate, excluding all cancers (controls excluding all cancers)

5.00

1.89

1.0

—

Malignant neoplasm of breast, ER-positive, excluding all cancers (controls excluding all cancers)

3.75

1.87

1.2

1.0

—

Polyuria

2.39

1.85

1.0

1.1

—

Ptosis of eyelid

3.53

1.83

1.0

—

Malignant neoplasm of digestive organs

2.02

1.83

1.1

—

Acute appendicitis

143

1.72

1.82

1.1

—

Stroke, excluding SAH

128

0.41

1.81

1.0

1.1

—

Codeine

119

1.62

1.80

1.0

1.1

—

Cough

1.92

1.79

1.1

—

Asthma (only as main-diagnosis), excluding more controls

1.85

1.79

1.0

1.1

—

Intestinal stricture

2.17

1.77

1.1

—

All influenza

2.44

1.75

1.3

1.0

—

Asthma-related infections

122

1.77

1.74

1.0

1.1

—

Asthma, hospital admission 2, infections

122

1.77

1.74

1.0

1.1

—

DVT of lower extremities

2.50

1.73

1.1

—

Tramadol

112

1.66

1.72

1.1

—

Asthma (diagnoses ohter than nonallergic)

171

1.60

1.72

1.0

1.1

—

Stroke, including SAH

134

0.44

1.72

1.0

1.1

—

Asthma (only as main-diagnosis)

1.82

1.72

1.0

1.1

—

Monoamine oxidase A inhibitors

2.92

1.72

1.0

1.1

—

Open wound of lower leg

2.92

1.72

1.1

1.0

—

All influenza (not pneumonia)

2.92

1.72

1.4

1.1

—

Type 2 diabetes

170

0.52

1.71

1.1

—

Viral infections of the central nervous system

3.85

1.71

1.0

1.1

—

Delirium, not induced by alcohol and other psychoactive substances

3.84

1.71

1.0

—

Diarrhoea and gastroenteritis of presumed infectious origin

141

1.68

1.69

1.2

1.1

—

Coxarthrosis, primary

141

0.43

1.67

1.1

—

Tonsillectomy and adenotomy

1.86

1.66

1.2

1.1

—

Other disorders of skin and subcutaneous tissue

143

1.67

1.66

1.1

—

Irregular menses

2.07

1.65

1.0

—

Appendicitis, broad definition

150

1.65

1.1

—

Diseases of liver

2.03

1.64

1.0

1.2

—

Extrapyramidal and movement disorders

1.97

1.64

1.2

1.1

—

Venous thromboembolism

123

1.74

1.64

1.1

—

Drugs, medicaments and biological substances causing adverse effects in therapeutic use

3.57

1.61

1.0

—

Aortic valve malfunction, age under 60 years

3.57

1.61

1.0

1.2

—

Fibromyalgia

3.57

1.61

1.0

—

Diseases of appendix

151

1.63

1.59

1.1

—

5-aminosalicylic acid

2.50

1.59

1.3

1.1

—

Diseases of the skin and subcutaneous tissue

124

1.54

1.59

1.0

1.1

—

Acute appendicitis, no complications

113

1.77

1.58

1.1

—

Abnormal findings on diagnostic imaging of other body structures

3.00

1.58

1.0

—

ILD medications: azathioprine

3.00

1.58

1.2

1.1

—

Bacterial intestinal infections, IBD co-morbidities

2.69

1.58

1.1

1.0

—

Chronic periodontitis, including avohilmo

157

1.56

1.57

1.1

—

Bacterial Sepsis

1.87

1.57

1.1

—

Abrasion of teeth

2.37

1.57

1.0

1.2

—

Skin changes due to chronic exposure to nonionizing radiation

1.94

1.56

1.1

—

Paralytic ileus and intestinal obstruction

2.20

1.56

1.0

1.1

—

Parodontitis

157

1.55

1.1

—

Parodontitis or operation codes

157

1.55

1.54

1.1

—

Other heart diseases

1.82

1.54

1.1

—

Lower back pain or/and sciatica

170

1.51

1.53

1.1

—

In situ neoplasms

2.03

1.53

1.2

1.0

—

Other diseases of pleura

1.81

1.52

1.1

1.2

—

Nontoxic single thyroid nodule

3.34

1.52

1.0

—

Benign neoplasm: Parotid gland

3.34

1.52

1.2

1.0

—

Benign neoplasm of eye and adnexa

3.34

1.52

1.2

1.0

—

Other complications of surgical and medical care, not elsewhere classified

3.34

1.52

1.0

—

Other pleural conditions

3.34

1.52

1.0

—

Overexertion and strenuous or repetitive movements

3.34

1.52

1.6

1.1

—

Other bacterial intestinal infections

2.59

1.51

1.1

—

Other embolism and thrombosis

2.86

1.50

1.2

1.0

—

Recurring oral aphthae, including avohilmo

2.86

1.50

1.0

—

Azathioprine

2.86

1.50

1.2

1.0

—

Asthma, including avohilmo

166

1.47

1.50

1.0

1.1

—

Cardiovascular diseases

1.74

1.49

1.1

—

Autoimmune diseases

137

1.49

1.1

—

Gastro-oesophageal reflux disease

136

1.63

1.48

1.1

—

Other disorders of bone

2.43

1.47

1.3

1.1

—

Acute sinusitis

1.79

1.47

1.1

—

Presence of other functional implants

110

0.45

1.46

1.0

1.1

—

Conjunctivitis

141

1.61

1.46

1.2

1.1

—

Phlebitis and thrombophlebitis (not including DVT)

2.22

1.46

1.2

1.1

—

Myalgia

2.22

1.46

1.1

1.0

—

Coronary atherosclerosis

132

0.49

1.46

1.0

1.1

—

Spondyloarthritis

2.50

1.45

1.3

1.0

—

Sicca syndrome [Sjögren]

3.13

1.44

1.0

—

Urolithiasis

1.92

1.43

1.0

1.2

—

Mucosal proctocolitis

2.73

1.43

1.3

1.0

—

Direct fill therapy

2.73

1.43

1.0

1.1

—

Polycystic ovarian syndrome, consortium definition

1.70

1.43

1.0

—

Pulmonary heart disease

2.03

1.43

1.2

1.1

—

Pulmonary embolism

2.03

1.43

1.2

1.1

—

Glucosamine medication

111

0.43

1.42

1.0

1.1

—

Appendectomy

143

1.62

1.41

1.1

—

Diseases of vocal cords and larynx+other diseases of upper respiratory tract, no elsewhere classified

108

1.72

1.40

1.3

1.1

—

Malignant neoplasm of breast, HER2-negative, excluding all cancers (controls excluding all cancers)

2.54

1.40

1.1

1.0

—

Malignant neoplasm of breast, excluding all cancers (controls excluding all cancers)

2.54

1.40

1.1

1.0

—

Osteopathies and chondropathies

119

1.67

1.40

1.1

—

Lyme disease

2.17

1.39

1.0

1.1

—

Organic, including symptomatic, mental disorders

0.40

1.39

1.0

1.1

—

Heart failure, not strict

134

1.54

1.39

1.1

—

Hypertension, essential

110

1.56

1.39

1.1

—

Type 2 diabetes, definitions combined

166

0.57

1.38

1.2

1.1

—

Type 2 diabetes, strict (exclude DM1)

166

0.58

1.38

1.2

1.1

—

Obesity, other/unspecified

2.00

1.37

1.2

1.1

—

Benign neoplasm of other and unspecified endocrine glands

2.61

1.36

1.0

—

Chronic sinusitis

1.80

1.36

1.0

1.1

—

Coxarthrosis, primary, with hip surgery

118

0.40

1.36

1.0

1.1

—

Hydronephrosis

2.94

1.36

1.0

—

Abnormalities of breathing

130

1.51

1.35

1.1

—

Use of memantine

0.00

1.35

0.0

1.0

—

Use of other anti-dementia drugs

0.00

1.35

0.0

1.0

—

Excessive attrition of teeth

2.02

1.35

1.0

1.2

—

Actinic keratosis

1.87

1.34

1.1

—

Myocardial infarction, with ST-elevation

0.00

1.33

0.0

1.1

—

Other spirochaetal diseases

2.13

1.33

1.0

1.1

—

Osteoporosis

2.15

1.33

1.1

1.0

—

Colorectal adenocarcinoma

0.00

1.32

0.0

1.1

—

Acute alcohol intoxication, ICD10

0.00

1.32

0.0

1.2

—

Other or unspecified ileus, impaction or obstruction

2.35

1.29

1.0

1.1

—

2.78

1.28

1.0

1.2

—

Lung diseases due to external agents

2.78

1.28

1.0

—

Other obstetric conditions, not elsewhere classified

2.36

1.28

1.0

1.1

—

Acute upper respiratory infections

160

1.45

1.28

1.3

1.1

—

Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium

2.36

1.28

1.0

1.1

—

Other diseases of upper respiratory tract

141

1.44

1.27

1.2

1.1

—

Diseases of pulp and periapical tissues

1.94

1.27

1.1

—

Radiculopathy

2.29

1.26

1.0

1.1

—

Hypertensive diseases

112

1.52

1.26

1.1

—

Hypertension

112

1.52

1.26

1.1

—

Dentofacial anomalies [including malocclusion]

2.26

1.25

1.0

—

Diabetes, insuline treatment (Kela reimbursement), excluding more controls

172

0.60

1.24

1.1

—

malignant neoplasm of female genital organs

2.40

1.24

1.0

—

Speech therapy

2.04

1.21

1.0

1.1

—

Inflammatory disease of uterus

2.63

1.21

1.0

1.1

—

Cerebral palsy and other paralytic syndromes

2.63

1.21

1.2

1.1

—

Chronic periapical parodontitis

2.16

1.21

1.1

1.2

—

Pain in throat and chest

123

1.49

1.20

1.0

1.1

—

Dorsalgia

131

1.45

1.19

1.1

—

Macular pucker

2.31

1.18

1.0

—

Iridocyclitis

2.11

1.18

1.3

1.1

—

Other reaction to severe stress, and adjustment disorders

1.88

1.17

1.0

1.1

—

Other heart diseases, wide

136

1.46

1.17

1.1

—

Disorders of adult personality and behaviour

2.00

1.16

1.0

1.1

—

Alcohol abuse, main dg

0.00

1.16

0.0

1.1

—

Ischaemic Stroke, excluding all haemorrhages

117

0.52

1.16

1.1

—

Benign neoplasm: Skin of other and unspecified parts of face

2.50

1.15

1.0

—

Dysphagia

2.05

1.15

1.3

1.1

—

Pain in joint

1.60

1.15

1.0

1.1

—

Deviated nasal septum

1.80

1.14

1.5

1.1

—

Alcohol abuse, main dg, excluding more controls

0.00

1.14

0.0

1.2

—

Disorders of conjunctiva

159

1.47

1.13

1.2

1.1

—

Sleep apnoea

156

1.43

1.13

1.1

—

Disorders of other endocrine glands

1.72

1.13

1.1

—

Acute renal failure

2.00

1.12

1.1

—

Other and unspecified disorders of vitreous body

1.68

1.11

1.0

1.1

—

Lung cancer and mesothelioma

2.30

1.11

1.1

1.0

—

Coxarthrosis [arthrosis of hip](FG)

103

0.49

1.11

1.1

—

Other diseases of liver

2.26

1.10

1.0

1.1

—

Codeine or tramadol medication

160

1.38

1.10

1.0

1.1

—

Ulcerative colitis, NAS

2.38

1.09

1.4

1.0

—

IBD patients in KELA-register

1.95

1.08

1.3

1.1

—

Pulmonary heart disease, diseases of pulmonary circulation

1.82

1.08

1.2

1.0

—

Sleep apnoea, including avohilmo

156

1.41

1.08

1.1

—

Complications of surgical and medical care, not elsewhere classified

167

1.42

1.08

1.1

—

Biguanides

166

0.63

1.07

1.1

—

Obesity related asthma

1.76

1.06

1.0

1.1

—

Disorders of synovium and tendon

110

0.49

1.05

1.3

1.1

—

Sciatica+with lumbago

107

1.60

1.05

1.0

1.1

—

Benign neoplasm: Rectum

2.12

1.05

1.1

1.0

—

Disorders of lipoprotein metabolism and other lipidaemias

131

1.44

1.05

1.1

—

Lumbar disc prolapse

121

1.51

1.04

1.0

1.1

—

Other maternal disorders predominantly related to pregnancy

0.45

1.04

1.0

1.1

—

Dislocation, sprain and strain of joints and ligaments at neck level

2.27

1.03

1.2

1.1

—

Diseases of inner ear

119

1.56

1.03

1.2

1.1

—

Other disorders of patella

2.06

1.02

1.1

1.0

—

Type 2 diabetes, definitions combined, including avohilmo

165

0.65

1.02

1.2

1.1

—

Chronic lower respiratory diseases

163

1.36

1.02

1.1

—

Other intervertebral disc disorders

123

1.44

1.02

1.1

—

Use of hypnotics and sedatives

150

1.39

1.02

1.1

—

Diabetes medication

176

0.66

1.01

1.2

1.1

—

Other (not insulin) diabetes medications

167

0.65

1.00

1.2

1.1

—

Calculus of kidney and ureter

1.77

1.00

1.0

1.2

—

Parodontitis or/and operation codes

1.52

0.99

1.2

1.1

—

Opioids

119

1.41

0.99

1.1

—

Diabetes, insulin treatment (Kela reimbursement)

176

0.66

0.99

1.1

—

Benign lipomatous neoplasm

1.80

0.98

1.0

1.1

—

Retinal detachment with retinal break

2.18

0.98

1.0

—

Malignant melanoma

2.17

0.98

1.0

—

Somatoform disorder

0.00

0.97

0.0

1.1

—

Schizophrenia

0.00

0.97

0.0

1.1

—

Personality disorders, excluding more controls

1.80

0.96

1.0

1.1

—

Dermatitis and eczema

173

1.36

0.96

1.1

—

Parodontitis and operation codes

160

1.41

0.95

1.1

—

Sleep disorders (combined)

162

1.38

0.95

1.1

—

Other cataract

1.59

0.95

1.1

—

1.65

0.95

1.0

1.1

—

Emergency coronary revascularization (for ACS)

106

0.54

0.95

1.0

1.2

—

Personality disorders

1.77

0.94

1.0

1.2

—

Other headache syndromes

1.65

0.94

1.1

—

Pleural effusion

2.22

0.93

1.0

—

Allergic rhinitis

1.75

0.93

1.0

1.1

—

Early onset COPD, excluding more controls

2.14

0.91

1.7

1.0

—

Other benign neoplasms of skin

1.67

0.91

1.2

1.1

—

Other dorsopathies, not elsewhere classified

131

1.37

0.90

1.1

—

Coxarthrosis

0.53

0.90

1.1

—

Hernia

153

1.37

0.88

1.1

—

Atopic dermatitis

1.57

0.88

1.2

1.1

—

Low back pain

129

1.43

0.87

1.2

1.1

—

Exposure to other specified factors

158

1.42

0.87

1.1

—

Reimbursement for rheumatic diseases

127

1.49

0.87

1.2

1.1

—

L04AA Selective immunosuppressants

1.86

0.87

1.1

—

Inflammatory bowel disease, strict (require KELA)

1.86

0.87

1.3

1.1

—

Retinal breaks without detachment

2.00

0.87

1.2

1.0

—

Maternal care for known or suspected abnormality of pelvic organs

1.97

0.84

1.0

—

Adjustment and management of implanted device

1.94

0.84

1.3

1.1

—

Acute and subacute iridocyclitis

1.94

0.84

1.3

1.1

—

Covid-19 suspected case

1.94

0.84

1.0

1.1

—

Other systemic involvement of connective tissue

1.78

0.84

1.3

1.0

—

Diseases of the respiratory system

1.48

0.84

1.0

1.1

—

Persons with potential health hazards related to communicable diseases

1.70

0.84

1.1

—

Concussion

0.54

0.83

1.0

1.2

—

Primary gonarthrosis, bilateral

122

0.57

0.83

1.1

—

Voice disturbances

1.74

0.82

1.3

1.0

—

Gout, FINNGEN

1.69

0.82

1.6

1.1

—

Postpartum care and examination

0.00

0.82

0.0

1.1

—

Single spontaneous delivery

0.48

0.81

1.0

1.1

—

Complications of labour and delivery

0.55

0.81

1.0

—

Functional dyspepsia

1.70

0.80

1.4

1.1

—

Disorders of vitreous body

111

1.50

0.80

1.0

1.1

—

Special screening examination for infectious and parasitic diseases

1.87

0.80

1.2

—

Disorders of vestibular function (Vertigo)

1.54

0.79

1.3

1.1

—

Vaginitis/vulvovaginitis/vulvitis/abscess of vulva

0.00

0.79

0.0

1.0

—

Care involving use of rehabilitation procedures

116

1.47

0.78

1.1

—

Mycoses

1.67

0.78

1.0

1.1

—

Benign neoplasm: Skin of eyelid, including canthus

0.00

0.78

0.0

1.0

—

Depression medications

2.29

0.78

1.0

—

Temporomandibular joint disorders, including avohilmo

1.66

0.78

1.0

1.1

—

L02BA Anti-estrogens

0.00

0.77

0.0

1.0

—

Other disorders of eyelid

1.53

0.77

1.1

—

Disorders of vitreous body and globe

112

1.48

0.76

1.0

1.1

—

UC patients in KELA-register ( KELA 208 prior to 1994, or ICD K51)

1.77

0.76

1.3

1.1

—

Acute appendicitis, with complications

1.77

0.76

1.2

1.1

—

Use of donepezil

0.00

0.76

0.0

1.0

—

Antihypertensive medication - note that there are other indications

1.44

0.75

1.0

1.1

—

Ischaemic heart disease, wide definition

139

0.68

0.74

1.1

—

Ischemic heart diseases

139

0.68

0.74

1.1

—

Nontoxic goitre/thyroid nodule

1.67

0.74

1.0

—

Superficial injury of head

1.84

0.73

1.0

1.1

—

Other arrhythmias

114

1.41

0.73

1.2

1.1

—

Spondylopathies (FG)

2.00

0.72

1.4

1.0

—

Symptoms and signs involving the nervous and musculoskeletal systems

136

0.59

0.72

1.1

—

Endometriosis of ovary

2.00

0.72

1.0

—

Bleeding

160

0.68

0.72

1.1

—

Benign neoplasm: Rectum, anus and anal canal

1.80

0.72

1.1

—

Use of pramipexole

1.80

0.72

1.0

1.1

—

Fracture of skull and facial bones

1.80

0.72

1.1

1.2

—

Systemic connective tissue disorders

1.62

0.71

1.2

1.1

—

Vasomotor and allergic rhinitis

1.62

0.71

1.0

1.1

—

Glucagon-like peptide-1 (GLP-1) analogues

131

0.63

0.71

1.4

1.1

—

Seborrhoeic keratosis

1.75

0.71

1.3

1.1

—

All dysplastic lesions of the cervix uteri, vagina or vulva

1.74

0.71

1.1

1.0

—

Disorder of lipoprotein metabolism, unspecified

1.92

0.70

1.4

1.1

—

Endometriosis

1.70

0.70

1.1

—

Other/unspecified dorsalgia

1.54

0.70

1.0

1.1

—

Pollen allergy

1.90

0.70

1.0

1.1

—

Glaucoma

127

0.62

0.70

1.2

1.1

—

Symptoms and signs involving the urinary system

143

1.35

0.69

1.0

1.1

—

Chondropathies

1.85

0.68

1.4

1.1

—

Ectopic pregnancy

1.85

0.68

1.2

1.0

—

Other predominantly sexually transmitted diseases, not elsewhere classified

1.85

0.68

1.0

1.1

—

Exclusions for E4_PCOS_BROAD

1.85

0.68

1.0

1.1

—

Gestational diabetes (for exclusion)

1.65

0.67

1.0

1.1

—

Gout

1.59

0.67

1.6

1.1

—

Cardiodefibrillation

0.54

0.66

1.0

1.2

—

Specific personality disorders

1.63

0.66

1.0

1.1

—

Vertebral, anorectal, cardiavascular, thracheoesophagial, renal and limb anomaly

1.79

0.66

1.0

1.1

—

Erosion of teeth, including avohilmo

1.79

0.66

1.2

—

Seropositive rheumatoid arthritis, strict definition

1.79

0.66

1.0

—

Obstructed labour due to maternal pelvic abnormality

1.79

0.66

1.2

1.0

—

Benign neoplasm of other and ill-defined parts of digestive system

1.79

0.66

1.0

—

Carbimazole or st.post thyroidectomy, condition for graves disease

1.79

0.66

1.2

1.0

—

Rotator cuff syndrome

113

1.38

0.66

1.3

1.1

—

Focal epilepsy, mode (most common among epilepsy diagnosis)

1.79

0.66

1.0

1.1

—

Delivery

0.58

0.65

1.0

1.1

—

Ventral hernia

1.59

0.65

1.0

1.1

—

Subjective visual disturbances

1.59

0.65

1.0

1.1

—

Factors influencing health status and contact with health services

1.67

0.65

1.2

1.1

—

Malignant neoplasm of prostate

0.56

0.63

1.3

1.2

—

Injuries to the shoulder and upper arm

178

0.71

0.63

1.0

1.1

—

Coronary angioplasty

0.56

0.62

1.0

1.2

—

Sulfasalazine

1.63

0.62

1.1

1.0

—

Ulcerative colitis (strict definition, require KELA, min 2 HDR)

1.67

0.61

1.4

1.1

—

Lichen planus, including avohilmo

1.67

0.61

1.0

1.1

—

Ulcerative colitis (strict definition, require KELA)

1.67

0.61

1.4

1.1

—

Dental pulpitis 1

148

1.26

0.61

1.2

1.1

—

Diseases of pulp and periapical tissues, including avohilmo

148

1.26

0.61

1.2

1.1

—

Dental pulpitis 4

148

1.26

0.61

1.2

1.1

—

Tinnitus

1.60

0.61

1.1

—

COPD (mode)

1.59

0.61

1.5

1.1

—

Diverticular disease of intestine

114

1.34

0.61

1.3

1.1

—

Shoulder lesions

121

1.32

0.60

1.2

1.1

—

Dorsopathies

132

1.28

0.60

1.1

—

Arthropathic psoriasis

0.00

0.60

0.0

1.2

—

Noninflammatory disorders of female genital tract

1.55

0.60

1.0

1.1

—

Triptan medication for migraine, min. 3 purchases

1.49

0.60

1.0

1.1

—

Psoriatic arthropathies

0.00

0.60

0.0

1.0

—

Superficial injury of shoulder and upper arm

0.00

0.60

0.0

1.1

—

Toxic effects of substances chiefly nonmedicinal as to source

0.00

0.60

0.0

1.1

—

Mixed conductive and sensorineural hearing loss

0.00

0.60

0.0

1.0

—

Malignant neoplasm of colon

0.00

0.60

0.0

1.0

—

Thyrotoxicosis with diffuse goitre

0.00

0.60

0.0

1.0

—

Peripheral artery operations in Hilmo

0.00

0.60

0.0

1.0

—

Polyarthropathies

109

1.35

0.60

1.4

1.1

—

Complications of procedures, not elsewhere classified

165

1.31

0.59

1.1

—

Retained placenta and membranes, without haemorrhage

0.00

0.59

0.0

1.0

—

Irritable bowel syndrome

1.54

0.59

1.0

1.1

—

Exclusions for E4_PCOS_CONSORTIUM

1.39

0.59

1.0

1.1

—

Delivery, wide proxy

0.55

0.59

1.0

1.1

—

Other systemic involvement of connective tissue (FG)

1.53

0.59

1.3

1.0

—

Diplopia

0.00

0.58

0.0

1.0

—

Superficial injury of hip and thigh

0.00

0.58

0.0

1.0

—

Angina pectoris

118

0.69

0.58

1.1

—

Acute bronchitis

1.49

0.57

1.1

—

Other joint disorders

120

1.29

0.57

1.2

1.1

—

Substance use, excluding alcohol

1.71

0.57

1.0

1.1

—

Finngen Rheumatological endpoints

139

1.27

0.57

1.3

1.1

—

Anterior Iridocyclitis

1.67

0.56

1.3

1.1

—

Endometriosis ASRM stages 3,4

1.67

0.56

1.2

1.0

—

Other respiratory disorders and diseases

1.67

0.56

1.2

1.0

—

Other diseases of the respiratory system

1.67

0.56

1.2

1.0

—

Cystitis

117

1.31

0.56

1.1

—

Other symptoms and signs involving the nervous and musculoskeletal systems

0.57

0.56

1.2

1.1

—

Carpal tunnel syndrome

145

0.68

0.56

1.0

1.1

—

Coronary revascularization (ANGIO or CABG)

0.64

0.56

1.0

1.1

—

Injury of muscle and tendon at shoulder and upper arm level

0.56

0.55

1.0

1.1

—

Other and unspecified polyneuropathies, also in other diseases

1.62

0.55

1.2

1.1

—

Focal epilepsy

1.62

0.55

1.0

1.1

—

Soft tissue disorders related to use, overuse and pressure

1.54

0.55

1.2

1.1

—

Meniscus derangement

102

1.34

0.55

1.3

1.1

—

Major coronary heart disease event

138

0.72

0.54

1.1

—

Varicose veins

121

0.69

0.54

1.1

—

Symptoms and signs involving speech and voice

1.50

0.54

1.3

1.1

—

Other external causes of accidental injury

105

1.29

0.54

1.1

—

Disorders of sclera, cornea, iris and ciliary body

125

1.36

0.53

1.2

1.1

—

Other soft tissue disorders, not elsewhere classified

136

1.27

0.53

1.1

—

Dental pulpitis 4, only avohilmo

152

1.24

0.53

1.3

1.1

—

Neurological diseases, wide definition

1.57

0.53

1.0

1.1

—

Fall on same level

163

1.23

0.53

1.1

—

Disturbances of skin sensation

1.54

0.53

1.0

1.1

—

Atherosclerosis, excluding cerebral and coronary sclerosis

0.61

0.52

1.0

1.1

—

Disorders of skin appendages

1.43

0.52

1.0

1.1

—

Intracranial trauma

101

0.67

0.52

1.0

1.2

—

Nonsuppurative otitis media

1.52

0.52

1.0

1.1

—

External causes of morbidity and mortality

1.31

0.52

1.1

—

Fall on same level involving ice and snow

132

0.68

0.51

1.1

—

Gout, strict definition

1.50

0.51

2.2

1.1

—

Lichen ruber planus, wide definition including periferal and oral lichen planus

1.50

0.51

1.0

1.1

—

All anxiety disorders

1.37

0.51

1.0

1.1

—

Other specific joint derangements/joint disorders

119

1.30

0.51

1.2

1.1

—

Non-ischemic cardiomyopathy

1.48

0.51

1.1

—

Dental pulpitis 1, only avohilmo

153

1.23

0.51

1.3

1.1

—

Other acute lower respiratory infections

112

1.36

0.51

1.1

—

Fitting and adjustment of other devices

1.40

0.51

1.1

—

Other hammer toe(s) (acquired)

1.48

0.50

1.0

1.1

—

Abnormal findings on examination of blood, without diagnosis

102

1.38

0.50

1.2

1.1

—

malignant neoplasm of male genital organs

0.64

0.50

1.3

1.2

—

Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified (FINNGEN)

1.41

0.50

1.1

1.2

—

Urticaria and erythema

1.49

0.49

1.0

1.1

—

Statin medication

114

0.74

0.49

1.1

—

Peripheral artery disease

0.65

0.49

1.0

1.1

—

Abnormal findings in secretions and smears from cervix uteri vagina vulva

1.46

0.49

1.1

1.0

—

Dizziness and giddiness

146

1.28

0.48

1.1

—

Episodal and paroxysmal disorders

142

1.23

0.48

1.0

1.1

—

Fissure and fistula of anal and rectal regions

1.52

0.48

1.0

1.1

—

Complications of medical and surgical care

163

1.28

0.48

1.1

—

Diseases of middle ear and mastoid

1.35

0.48

1.0

1.1

—

Symptoms and signs involving the circulatory and respiratory systems

130

1.23

0.47

1.1

—

Symptoms and signs involving cognition, perception, emotional state and behaviour

164

1.24

0.47

1.1

—

Paroxysmal tachycardia

1.44

0.46

1.0

1.2

—

Sequelae of cerebrovascular disease

1.44

0.46

1.2

1.1

—

Glaucoma suspect

0.59

0.45

1.4

1.1

—

Unspecified mental disorder

0.59

0.45

1.0

1.1

—

Continuous positive airway pressure

1.40

0.45

1.3

1.2

—

Major coronary heart disease event excluding revascularizations

129

0.75

0.44

1.1

—

Contraceptive management

0.65

0.43

1.2

1.1

—

Maternal care for other known or suspected fetal problems

1.60

0.43

1.0

1.1

—

Intracranial injury

127

0.68

0.43

1.0

1.1

—

Polyp of the female genital tract

1.41

0.43

1.0

1.1

—

Disorders of parathyroid gland

1.59

0.42

1.2

1.0

—

Recurrent or chronic depression

0.62

0.42

1.0

1.2

—

Insulin medication

139

0.74

0.42

1.2

1.1

—

Developmental endpoint to exclude non autoimmune-cases from E4_HYTHY_AI_STRICT

1.43

0.42

1.1

—

Other and unspecified iron deficiency

1.43

0.42

1.1

—

Valvular operations

1.56

0.42

1.0

1.1

—

Adverse effects, not elsewhere classified

1.56

0.42

1.8

1.1

—

Focal epilepsy, strict definition

1.56

0.42

1.0

1.1

—

Benign paroxysmal vertigo

1.40

0.42

1.4

1.1

—

135

0.73

0.42

1.0

1.1

—

Postmenopausal bleeding

1.37

0.42

1.0

1.1

—

Accidents

105

1.24

0.41

1.2

1.1

—

Allergic conjunctivitis

103

1.34

0.41

1.0

1.1

—

Blepharochalasis

1.38

0.41

1.0

1.1

—

Multiple delivery

0.00

0.41

0.0

1.1

—

Adenocarcinoma and papilloma adenocarcinoma of rectum

0.00

0.41

0.0

1.0

—

Bacterial, viral and other infectious agents

0.00

0.41

0.0

1.1

—

Vitreous haemorrhage

0.00

0.41

0.0

1.0

—

Pilonidal cyst

0.00

0.41

0.0

1.1

—

Graves disease, strict definition

0.00

0.41

0.0

1.0

—

Superficial injury of forearm

0.00

0.41

0.0

1.1

—

Carcinoma in situ of breast, intraductal

0.00

0.41

0.0

1.0

—

Other diseases of arteries and capillaries

0.00

0.41

0.0

1.0

—

Open wound of ankle and foot

0.00

0.41

0.0

1.1

—

Burns and corrosions of external body surface, specified by site

0.00

0.41

0.0

1.1

—

Rosacea

0.00

0.41

0.0

1.1

—

Spontaneous rupture of synovium and tendon

0.00

0.40

0.0

1.0

—

Other mental disorders due to brain damage and dysfunction and to physical disease

0.00

0.40

0.0

1.0

—

Colon adenocarcinoma

0.00

0.40

0.0

1.0

—

Otitis externa, unspecified

0.00

0.40

0.0

1.1

—

Leiomyoma of uterus

1.33

0.40

1.0

1.1

—

Persons encountering health services for examination and investigation

1.29

0.40

1.1

—

Use of disulfiram, acamprosate or naltrexone

0.00

0.40

0.0

1.2

—

Other psoriatic arthropathies

0.00

0.40

0.0

1.1

—

Psoriatic arthropathies, ICD10

0.00

0.40

0.0

1.1

—

Cervicocranial syndrome

0.00

0.40

0.0

1.1

—

Polymyalgia rheumatica

0.00

0.40

0.0

1.0

—

Ovarian cyst

1.41

0.40

1.1

—

Suppurative and unspecified otitis media

1.31

0.39

1.0

1.1

—

Injuries to the hip and thigh

0.67

0.39

1.0

1.1

—

Familial hypercholesterolemia

1.43

0.39

1.4

1.1

—

Persistent mood disorders

1.43

0.39

1.2

1.1

—

Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis

1.33

0.39

1.2

1.0

—

All dysplastic lesions of the cervix uteri

1.43

0.39

1.2

1.0

—

Degeneration of macula and posterior pole

1.33

0.39

1.1

—

Pedal cyclist injured in other and unspecified transport accidents

0.00

0.39

0.0

1.1

—

Intracerebral haemorrhage

0.00

0.39

0.0

1.0

—

Other diseases of urinary system

140

1.21

0.39

1.2

1.1

—

Retinal detachments and breaks

1.38

0.38

1.1

—

Other disorders of teeth and supporting structures

1.39

0.38

1.0

1.2

—

Use of eye-antiallergens (taken as indicator of allergic/atopic conjunctivitis)

1.33

0.38

1.0

1.1

—

Acetic acid derivatives and related substances

1.30

0.37

1.2

—

Anti-inflammatory and antirheumatic products, non-steroids

0.64

0.37

1.0

1.2

—

Diseases of external ear

1.32

0.37

1.0

1.1

—

Presence of cardiac and vascular implants and grafts

0.69

0.37

1.3

1.1

—

Hard cardiovascular diseases

145

0.80

0.37

1.1

—

Genitourinary diseases

1.27

0.37

1.1

1.2

—

Acute pancreatitis

1.35

0.37

1.2

1.1

—

Complications predominantly related to the puerperium

1.35

0.37

1.0

—

Acute pancreatitis (for exclusion)

1.35

0.37

1.2

1.1

—

Keratitis

1.29

0.36

1.0

1.1

—

COPD, hospital admission 2, with asthma infections

0.66

0.36

1.8

1.1

—

Pain (limb, back, neck, head abdominally)

1.24

0.36

1.1

—

Insulin, combination of fast acting with intermediate-acting or long-acting

145

0.76

0.36

1.2

1.1

—

Other abnormal uterine and vaginal bleeding

1.43

0.36

1.2

1.1

—

Persons with potential health hazards related to socioeconomic and psychosocial circumstances

1.45

0.35

1.2

1.1

—

Hypothyroidism, other/unspecified

148

0.80

0.35

1.1

—

Abnormal serum enzyme levels

0.66

0.35

1.0

1.2

—

Gout, unspecified

1.40

0.35

2.2

1.1

—

Benign neoplasm of colon, rectum, anus and anal canal

138

1.24

0.35

1.2

1.1

—

Injuries to the neck

1.40

0.35

1.2

1.1

—

Cervicobrachial syndrome

1.40

0.35

1.0

1.1

—

Mental and behavioural disorders due to alcohol

122

0.72

0.35

1.0

1.1

—

Malignant neoplasm of respiratory system and intrathoracic organs

1.38

0.34

1.3

1.1

—

Dental caries 2 and operation codes

136

1.23

0.34

1.1

—

Nasal polyp

1.36

0.34

1.3

1.1

—

Polyneuropathies and other disorders of the peripheral nervous system

1.36

0.34

1.2

1.1

—

Diseases of the musculoskeletal system and connective tissue

1.27

0.34

1.1

—

Contact with and exposure to communicable diseases

1.36

0.34

1.0

1.1

—

Disorders of breast

1.32

0.34

1.0

—

Diseases of the eye and adnexa

1.21

0.33

1.1

—

Other chronic obstructive pulmonary disease, including avohilmo

111

0.75

0.33

1.4

1.1

—

Papulosquamous disorders

0.69

0.33

1.3

1.1

—

Other and unspecified effects of external causes

1.28

0.32

1.7

1.1

—

Any mental disorder, or suicide (or attempt), or psychic disorders complicating pregnancy, partum or puerperum or nerve system disorders, excluding more controls

1.28

0.32

1.0

1.1

—

Hypothyreosis and Thyroxine purchase for inclusion criteria

153

0.82

0.32

1.1

—

Pure hypercholesterolaemia

128

1.21

0.32

1.1

—

Injuries to the elbow and forearm

149

0.79

0.31

1.1

—

Neurological diseases

110

1.19

0.31

1.0

1.2

—

Unstable angina pectoris

0.69

0.30

1.1

—

Metabolic disorders

148

1.18

0.30

1.1

—

Hypothyroidism, strict autoimmune, 3 medication purchases required

142

0.82

0.30

1.1

—

Persons encountering health services in circumstances related to reproduction

0.76

0.30

1.1

—

Other disorders of urethra and urinary system

110

1.23

0.30

1.1

—

130

0.78

0.30

1.0

1.1

—

Other neurological diseases

149

0.81

0.29

1.0

1.1

—

Other special examinations and investigations of persons without complaint or reported diagnosis

1.23

0.29

1.2

1.1

—

Alcohol use disorder, ICD-based

106

0.75

0.29

1.0

1.1

—

Cholelithiasis, broad definition with cholecystitis

152

1.17

0.28

1.0

1.1

—

Asthma/COPD (KELA code 203)

163

1.17

0.28

1.0

1.1

—

Disorders of gallbladder, biliary tract and pancreas

161

1.16

0.28

1.0

1.1

—

Open wound of wrist and hand

102

1.26

0.28

1.0

1.1

—

Dental operations

1.21

0.28

1.2

1.1

—

Transient ischemic attack

116

0.79

0.27

1.0

1.1

—

Mental and behavioural disorders due to alcohol, excluding acute intoxication

116

0.77

0.27

1.0

1.1

—

Epilepsy

1.25

0.27

1.0

1.2

—

Dental pulpitis 2

100

0.82

0.27

1.1

—

Sensorineural hearing loss

136

0.82

0.27

1.1

—

Heart failure, strict

107

1.21

0.27

1.1

—

Other diseases of the digestive system

1.23

0.27

1.1

—

Nerve, nerve root and plexus disorders

176

0.86

0.27

1.1

—

Cholelithiasis

150

1.17

0.26

1.0

1.1

—

General examination and investigation of persons without complaint and reported diagnosis

1.22

0.26

1.0

1.1

—

Primary open-angle glaucoma

0.70

0.26

1.2

1.0

—

Kela-code for severe mental illness

0.68

0.26

1.0

1.1

—

Retention of urine

1.23

0.25

1.1

—

Abnormalities of heart beat

1.21

0.25

1.1

—

Unspecified fall

104

1.24

0.25

1.1

—

Atrial fibrillation and flutter

0.71

0.24

1.2

—

Obesity due to excess calories

1.25

0.24

1.1

—

Type 2 diabetes, wide definition

146

0.85

0.24

1.1

—

Insulin, fast-acting

0.72

0.24

1.0

1.1

—

Disorders of choroid and retina

144

1.16

0.24

1.1

—

Gonarthrosis,primary

154

0.86

0.24

1.2

1.1

—

Fenamates

1.35

0.24

1.0

1.2

—

Insulin, fast-acting or short human

0.71

0.24

1.0

1.1

—

Asthma, hospital admissions , main diagnosis only

178

1.16

0.23

1.0

1.1

—

Other functional intestinal disorders

1.24

0.23

1.3

1.1

—

Cervicalgia

1.32

0.23

1.0

1.1

—

Cardiomyopathy

1.32

0.23

1.0

1.1

—

Peritonsillar abscess

1.32

0.23

1.2

1.1

—

Heart failure,strict

1.20

0.23

1.1

1.2

—

STROKE

117

0.83

0.22

1.0

1.1

—

Alcohol use disorder, Swedish definition

126

0.81

0.22

1.0

1.1

—

Non-selective monoamine reuptake inhibitors

0.75

0.22

1.0

1.1

—

Dental pulpitis 2, only avohilmo

103

0.84

0.22

1.1

—

Obesity

133

1.19

0.22

1.1

—

Valvular heart disease excluding rheumatic fever

1.20

0.22

1.1

—

Cardiac arrhythmias

107

1.17

0.22

1.1

—

Alzheimer’s disease (Atypical or mixed), excluding more controls

0.00

0.21

0.0

1.0

—

Other specified cerebrovascular diseases, other cerebrovascular disorders in diseases classified elsewhere

0.00

0.21

0.0

1.0

—

Medial epicondylitis

0.00

0.21

0.0

1.0

—

Astigmatism

0.00

0.21

0.0

1.0

—

Abnormal blood-pressure reading, without diagnosis

0.00

0.21

0.0

1.0

—

Other specified/unspecified disorders of synovium and tendon +Other specified/unspecified bursopathies

0.00

0.21

0.0

1.0

—

Other secondary gonarthrosis

0.00

0.21

0.0

1.0

—

Dystonia

0.00

0.21

0.0

1.0

—

Convalescence

0.00

0.21

0.0

1.0

—

Congenital malformations of ovaries, fallopian tubes and broad ligaments

0.00

0.21

0.0

1.0

—

Other and unspecified glaucoma

0.00

0.21

0.0

1.0

—

Cyst of kidney

0.00

0.21

0.0

1.0

—

Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck

0.00

0.21

0.0

1.0

—

Dislocation, sprain and strain of joints and ligaments of elbow

0.00

0.21

0.0

1.1

—

Visual impairment including blindness (binocular or monocular)

0.00

0.21

0.0

1.0

—

Dermatographic urticaria

0.00

0.21

0.0

1.0

—

Amputation

0.00

0.21

0.0

1.0

—

Hydrocephalus

0.00

0.21

0.0

1.0

—

MS-disease / Multiple Sclerosis

0.00

0.21

0.0

1.1

—

Other/unspecified enthesopathies of lower limb, excluding foot

0.00

0.21

0.0

1.1

—

Mental and behavioural disorders due to multiple drug use and use of multiple drugs and use of other psychoactive substances

0.00

0.21

0.0

1.2

—

Other and unspecified mood [affective] disorders

0.00

0.21

0.0

1.0

—

Type 1 diabetes, strict definition, subgroup 1

0.00

0.21

0.0

1.1

—

Abnormal findings on antenatal screening of mother

0.00

0.21

0.0

1.0

—

Parodontitis, under 40 years and operation codes

0.00

0.21

0.0

1.0

—

Parodontitis, operation under 40 years and operation codes

0.00

0.21

0.0

1.0

—

Parodontitis, under 40 years

0.00

0.21

0.0

1.0

—

Parodontitis, under 40 years, or operation codes

0.00

0.21

0.0

1.0

—

Eating disorders

0.00

0.21

0.0

1.0

—

Undefined dementia

0.00

0.21

0.0

1.0

—

Unspecified dementia

0.00

0.21

0.0

1.0

—

Other specified/unspecified soft tissue disorders

0.00

0.21

0.0

1.0

—

Neuralgia and neuritis, unspecified

0.00

0.21

0.0

1.0

—

Tongue abnormality

0.00

0.21

0.0

1.0

—

Presbyopia

0.00

0.21

0.0

1.1

—

Other and unspecified psoriasis

0.00

0.21

0.0

1.0

—

Alcohol withdrawal state with delirium

0.00

0.21

0.0

1.2

—

Correction of physiology of bite - demanding therapy visit

0.00

0.21

0.0

1.0

—

Thyroiditis

0.00

0.21

0.0

1.0

—

Normotensive glaucoma

0.00

0.21

0.0

1.0

—

Persistent delusional disorders

0.00

0.21

0.0

1.1

—

Idiopathic gout

0.00

0.21

0.0

1.0

—

Mental disorders, not otherwise specified

0.00

0.21

0.0

1.0

—

Type 1 diabetes, strict definition

0.00

0.21

0.0

1.2

—

Congenital malformations of genital organs

0.00

0.21

0.0

1.0

—

Artificial joint re-operation

0.00

0.21

0.0

1.0

—

Corns and callosities

0.00

0.21

0.0

1.0

—

Other and unspecified myopathies

0.00

0.21

0.0

1.0

—

Other and unspecified rosacea

0.00

0.21

0.0

1.0

—

Gestational [pregnancy-induced] oedema and proteinuria without hypertension

0.00

0.21

0.0

1.0

—

Abscess of anal and rectal regions

0.00

0.21

0.0

1.2

—

Diabetic neuropathy

0.00

0.20

0.0

1.1

—

Abdominal aortic aneurysm (AAA)

0.00

0.20

0.0

1.0

—

Acute laryngitis and tracheitis

0.00

0.20

0.0

1.0

—

Conductive and sensorineural hearing loss

145

0.86

0.20

1.1

—

Follow-up examination after treatment for conditions other than malignant neoplasms

1.23

0.20

1.1

1.2

—

Atopic dermatitis, strict definition with reimbursement

1.26

0.20

1.0

1.1

—

Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care

0.00

0.20

0.0

1.0

—

Divergent concomitant strabismus

0.00

0.20

0.0

1.1

—

Effects of foreign body entering through natural orifice

1.25

0.20

1.2

—

Insulin, intermediate and long-acting

131

0.82

0.20

1.2

1.1

—

Benzodiazepine use

177

1.13

0.20

1.0

1.1

—

Other complications of labour and delivery, not elsewhere classified

0.00

0.20

0.0

1.0

—

Female infertility

1.20

0.20

1.0

1.1

—

Falls/tendency to fall

148

1.12

0.20

1.0

1.1

—

Heart failure and bmi 25plus

1.25

0.20

1.1

—

Other arthrosis

1.18

0.19

1.4

1.1

—

Mouth breathing

1.21

0.19

1.0

1.1

—

Dental caries 1

112

0.87

0.19

1.1

—

Diseases of the digestive system

1.21

0.19

1.1

—

Dental caries, including avohilmo

112

0.87

0.19

1.1

—

Chronic diseases of tonsils and adenoids

118

0.86

0.19

1.1

—

Any mental disorder, or suicide (or attempt), or psychic disorders complicating pregnancy, partum or puerperium or nerve system disorders

1.13

0.18

1.0

1.1

—

Colonic or urogenital fistula

1.21

0.18

1.0

1.1

—

Obesity and other hyperalimentation

136

1.16

0.18

1.1

—

Procreative management

1.18

0.18

1.0

1.1

—

Other specified/unspecified arthritis

1.19

0.18

1.3

1.1

—

Menorrhagia

1.14

0.17

1.0

1.1

—

Other diseases of anus and rectum

1.17

0.17

1.0

1.1

—

Maternal care related to the fetus and amniotic cavity and possible delivery problems

0.74

0.17

1.0

1.1

—

Other and unspecified tonsillitis

1.12

0.17

1.9

1.1

—

Other antidepressants

141

1.11

0.17

1.1

—

Cervical disc disorders

1.22

0.17

1.2

1.1

—

Injuries to the wrist and hand

179

0.89

0.16

1.0

1.1

—

Diseases of arteries, arterioles and capillaries (FINNGEN)

1.16

0.16

1.0

1.2

—

Dental caries 1, only avohilmo

116

0.88

0.16

1.1

—

Excessive, frequent and irregular menstruation

1.14

0.16

1.0

1.1

—

Artrosis, including avohilmo

130

0.89

0.16

1.3

1.1

—

Infections of the skin and subcutaneous tissue

130

0.84

0.16

1.0

1.1

—

Other enthesopathies

1.14

0.16

1.4

1.1

—

Persons encountering health services in other circumstances

1.13

0.16

1.3

1.1

—

Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium

0.76

0.15

1.0

—

Hallux valgus (acquired)

1.16

0.15

1.0

1.1

—

All-cause Heart Failure

107

1.14

0.15

1.1

—

Injuries to the abdomen, lower back, lumbar spine and pelvis

0.75

0.15

1.0

1.1

—

Spontaneous abortion

1.13

0.15

1.0

—

Renal failure

1.18

0.15

1.2

—

Injuries to the head

178

1.10

0.15

1.1

—

Injuries to the knee and lower leg

173

1.09

0.15

1.1

—

Diseases of arteries, arterioles and capillaries

128

0.87

0.15

1.1

—

Iron deficiency anaemia

1.09

0.14

1.1

—

Spinal stenosis

0.84

0.14

1.0

1.1

—

Dental caries 2

140

1.12

0.14

1.2

1.1

—

Disorders of ocular muscles, binocular movement, accommodation and refraction

0.79

0.14

1.3

1.1

—

Endocrine, nutritional and metabolic diseases

114

0.89

0.14

1.1

—

Dental operations, only avohilmo

1.12

0.14

1.1

—

Malignant neoplasm of breast, HER2-negative

0.81

0.14

1.1

1.0

—

Spondylosis

110

0.86

0.13

1.0

1.1

—

COPD, hospital admissions

0.84

0.13

1.4

1.1

—

COPD, early/later onset

0.83

0.13

1.4

1.1

—

Visual disturbances and blindness

117

0.85

0.13

1.2

1.1

—

Triptan medication for migraine, single purchase ok

115

1.12

0.13

1.1

—

Migraine, single triptan purchase ok & required. ICD-code if available is included

115

1.12

0.13

1.1

—

Diseases of the ear and mastoid process

155

1.08

0.11

1.0

1.1

—

Fracture of lower leg, including ankle

133

1.12

0.11

1.1

—

Dental caries 3, only avohilmo

118

0.91

0.11

1.1

—

Cerebrovascular diseases

137

1.10

0.11

1.0

1.1

—

Dental caries 2, only avohilmo

136

1.10

0.10

1.2

1.1

—

Neurotic, stress-related and somatoform disorders

157

1.09

0.10

1.0

1.1

—

Female infertility, cervigal, vaginal, other or unspecified origin

1.15

0.10

1.0

1.1

—

Non-rheumatic valve diseases

1.12

0.10

1.1

—

Anxiety (asthma-related co-morbidities)

106

1.12

0.10

1.0

1.1

—

Atopic dermatitis, strict definition

1.14

0.10

1.0

1.1

—

Other gastritis (incl. Duodenitis)

1.14

0.10

1.0

1.1

—

Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

135

0.89

0.10

1.2

1.1

—

Depression

166

1.08

0.09

1.1

—

Inflammatory diseases of female pelvic organs

1.13

0.09

1.1

1.0

—

Myocardial infarction

0.89

0.09

1.1

1.2

—

Myocardial infarction, strict

0.88

0.09

1.2

—

Other anxiety disorders

1.15

0.09

1.0

1.1

—

Sequelae of external causes of morbidity and mortality

1.06

0.09

1.0

1.1

—

Other/unspecified seropositive rheumatoid arthritis (ICD-10)

1.06

0.09

1.0

1.1

—

Other menopausal disorders

1.12

0.09

1.0

1.1

—

Medical abortion

1.12

0.09

1.0

1.1

—

Unspecified haematuria

1.14

0.09

1.1

1.2

—

Gout, idiopatic and unspecified

1.11

0.09

2.2

1.1

—

Injuries to the ankle and foot

141

0.90

0.09

1.1

—

Early onset COPD

1.09

0.08

1.7

1.1

—

Female genital prolapse

1.05

0.08

1.0

1.1

—

Dental caries 2 and operation codes, only avohilmo

102

1.10

0.08

1.2

1.1

—

Sub-endpoint used in defining T1D endpoints

0.83

0.08

1.0

1.1

—

Sodium-glucose co-transporter 2 (SGLT2) inhibitors

0.81

0.08

1.0

1.2

—

Type 1 diabetes

0.81

0.08

1.0

1.1

—

Dental caries 3

116

0.93

0.08

1.1

—

Other disorders of fluid, electrolyte and acid-base balance

0.78

0.08

1.4

1.1

—

Fracture of rib(s), sternum and thoracic spine

0.77

0.08

1.0

1.1

—

Dislocation, sprain and strain of joints and ligaments of shoulder girdle

0.77

0.08

1.0

1.2

—

GI-bleeding

0.77

0.08

1.2

1.1

—

Hypertensive heart and/or renal disease

1.04

0.08

1.6

1.2

—

COPD

0.89

0.08

1.4

1.1

—

Striking against or struck by other objects

1.04

0.08

1.0

1.1

—

Cerebrovascular diseases (FINNGEN)

1.08

0.07

1.0

1.2

—

Anxiety disorders

159

1.07

0.07

1.0

1.1

—

Rheumatoid arthritis

1.05

0.07

1.3

1.1

—

Mental and behavioural disorders due to psychoactive substance use

135

0.91

0.07

1.0

1.1

—

Dental caries 1 and operation codes

120

1.07

0.07

1.1

—

Heart failure and coronary heart disease

0.86

0.07

1.1

—

Heart failure and antihypertensive medication

1.08

0.07

1.0

1.1

—

Internal derangement of knee

1.06

0.07

1.1

—

Dyspnoea

165

1.07

0.07

1.1

—

COPD related to multimorbidity

0.85

0.06

1.0

1.1

—

Malignant neoplasm of breast

0.88

0.06

1.1

1.0

—

Other chronic obstructive pulmonary disease

0.87

0.06

1.4

1.1

—

Hernia of abdominal wall

103

0.87

0.06

1.0

1.1

—

Injuries to the thorax

103

0.87

0.06

1.1

—

Other symptoms and signs involving cognitive functions and awareness

102

1.10

0.06

1.1

—

Psychiatric diseases

153

0.95

0.06

1.0

1.1

—

Congenital malformations, deformations and chromosomal abnormalities

114

1.09

0.06

1.0

1.1

—

Soft tissue disorders

137

0.95

0.05

1.1

—

Cholecystectomy

149

1.07

0.05

1.0

1.1

—

Constipation

156

1.06

0.05

1.0

1.1

—

Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

139

1.07

0.05

1.1

—

Substance abuse

134

0.93

0.04

1.0

1.1

—

Other disorders of ear

161

0.95

0.04

1.0

1.1

—

Exposure to unspecified factor

185

1.05

0.04

1.2

1.1

—

Hypothyroidism, strict autoimmune

113

0.94

0.04

1.1

—

Gonarthrosis [arthrosis of knee](FG)

118

0.95

0.03

1.2

1.1

—

Anxiety disorders, excluding more controls

139

1.05

0.03

1.0

1.1

—

Artificial joint operation, meniscal resection

160

0.96

0.03

1.3

1.1

—

Selective serotonin reuptake inhibitors

142

1.04

0.03

1.0

1.1

—

Gonarthrosis

1.05

0.03

1.2

1.1

—

Senile cataract

106

1.05

0.03

1.2

1.1

—

Myocardial infarction, without ST-elevation

1.09

0.03

1.1

1.2

—

Dental caries 3 and operation codes

123

0.96

0.03

1.1

—

Depression or dysthymia

105

0.96

0.01

1.1

—

Mood [affective] disorders

176

0.97

0.01

1.1

—

Other retinal disorders

126

0.96

0.01

1.1

—

Mood disorders

175

0.98

0.00

1.1

—

Substance abuse, excluding more controls

119

0.96

0.00

1.0

1.2

—

Diseases of male genital organs

0.96

0.00

1.2

—

Other nutritional deficiencies

141

1.04

0.00

1.1

—

Open wound of head

123

1.04

0.00

1.0

1.1

—

Dislocation, sprain and strain of joints and ligaments of knee

123

0.98

0.00

1.1

—

Mood disorders, excluding more controls

151

1.01

0.00

1.1

—

Arthrosis

104

1.00

0.00

1.4

1.1

—

Pregnancy with abortive outcome

1.00

0.00

1.0

1.1

—

Injury, poisoning and certain other consequences of external causes

1.00

0.00

1.1

—

Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified

162

1.00

0.00

1.1

—

Nutritional anaemias

103

1.04

0.00

1.1

—

Disorders of lens

111

1.02

0.00

1.2

1.1

—

Any mental disorder

153

0.98

0.00

1.0

1.1

—

Pain in limb

128

1.02

0.00

1.1

—

Inguinal hernia

102

0.99

0.00

1.1

1.2

—

Visual disturbances

105

0.95

0.00

1.2

1.1

—

Hyperplasia of prostate

0.98

0.00

1.1

1.2

—

Disorders of the thyroid gland

156

1.01

0.00

1.1

—

Fracture of forearm

115

0.98

0.00

1.1

—

Arthropathies

121

1.01

0.00

1.1

—

Spondylopathies

118

0.98

0.00

1.1

—

Benign neoplasm: Colon

129

0.99

0.00

1.2

1.1

—

Other surgical follow-up care

0.00

0.0

1.0

—

Urticaria

1.00

0.00

1.0

1.1

—

Use of galantamine

0.00

0.0

1.0

—

Disturbances of smell and taste

0.00

0.0

1.0

—

Oral lichen ruber planus

0.00

0.0

1.0

—

Other disorders of pigmentation

0.00

0.0

1.0

—

Hyperlipidaemia, other/unspecified

0.94

0.00

1.1

—

Brain meningioma

0.00

0.0

1.0

—

Gonococcal infection

0.00

0.0

1.0

—

Dislocation, sprain and strain of joints and ligaments at ankle and foot level

1.00

0.00

1.3

1.1

—

Speech and linguistic disorders

0.00

0.0

1.0

—

Generalized skin eruption due to drugs and medicaments

0.00

0.0

1.0

—

Postpartum haemorrhage due to anatomy

0.00

0.0

1.0

—

Fracture of shoulder and upper arm

1.01

0.00

1.0

1.1

—

Other acquired deformities of musculoskeletal system and connective tissue

0.00

0.0

1.0

—

Hypertrophic scar

0.00

0.0

1.0

—

Female infertility, associated with anovulation

0.00

0.0

1.2

—

Hyperfunction of pituitary gland

0.00

0.0

1.0

—

Use of ropinirole

0.00

0.0

1.0

—

Secondary right heart disease

0.00

0.0

1.0

—

Acute posthaemorrhagic anaemia

0.00

0.0

1.0

—

Separation of retinal layers (serosa)

0.00

0.0

1.2

—

Monoarthritis, not elsewhere classified

0.00

0.0

1.0

—

Intestinal malabsorption

0.00

0.0

1.0

—

Injury of nerves at wrist and hand level

0.00

0.0

1.0

—

Extreme obesity with alveolar hypoventilation

0.00

0.0

1.0

—

Benign neoplasm: Colon, unspecified

0.93

0.00

1.2

1.0

—

Psychotic depression

0.00

0.0

1.1

—

Cluster headache, wide,, including avohilmo

0.00

0.0

1.0

—

Other noninflammatory disorders of cervix uteri

0.00

0.0

1.0

—

Placenta praevia

0.00

0.0

1.0

—

Postmenopausal atrophic vaginitis

0.94

0.00

1.0

1.1

—

Subacute thyroiditis

0.00

0.0

1.0

—

Benign neoplasm: Rectosigmoid junction

0.00

0.0

1.0

—

Maternal care for cervical incompetence

0.00

0.0

1.0

—

Other arthritis (FG)

1.01

0.00

1.3

1.0

—

Invasive ventilation

0.00

0.0

1.0

—

Other or ill-defined heart diseases

0.00

0.0

1.0

—

Fibroblastic disorders

0.91

0.00

1.0

1.1

—

Deforming dorsopathies

0.86

0.00

1.0

1.1

—

Injuries involving multiple body regions

0.00

0.0

1.0

—

Erosion and ectropion of cervix uteri

0.00

0.0

1.0

—

Other disorders of adrenal gland

0.00

0.0

1.0

—

Unspecified abortion

0.00

0.0

1.1

—

Event of undetermined intent

0.00

0.0

1.0

—

Other/unspecified seropositive rheumatoid arthritis

0.98

0.00

1.0

1.1

—

Arterial embolism and thrombosis of lower extremity artery

0.00

0.0

1.0

—

Oter anti-inflammatory and antirheumatic agents, non-steroids

0.87

0.00

1.0

1.2

—

Other and unspecified noninflammatory disorders of ovary, fallopian tube and broad ligament

0.00

0.0

1.0

—

Optic neuritis

0.00

0.0

1.0

—

Endovascular or surgical operations to intracerebral aneurysms

0.00

0.0

1.0

—

Alzheimer’s disease (Early onset), excluding more controls

0.00

0.0

1.0

—

COPD, hospital admissions 3, with asthma pneumonia sepsis

0.87

0.00

1.8

1.1

—

Benign neoplasm: Skin of ear and external auricular canal

0.00

0.0

1.0

—

Other benign neoplasm of uterus: Other parts/unspecified

0.00

0.0

1.0

—

Convergent concomitant strabismus

0.00

0.0

1.0

—

ICD-8 DM (Sub-endpoint used for defining DM endpoints)

0.00

0.0

1.1

—

Pre-existing hypertension complicating pregnancy, childbirth and the puerperium

0.00

0.0

1.0

—

Benign neoplasm of urinary organs

0.00

0.0

1.0

—

Labour and delivery complicated by umbilical cord complications

0.00

0.0

1.0

—

Other disorders of veins

0.95

0.00

1.1

—

Prolapse and hernia of ovary and fallopian tube

0.00

0.0

1.0

—

Adenocarcinoma and ductal carcinoma of pancreas

0.00

0.0

1.0

—

Arthropathies in other diseases classified elsewhere

0.00

0.0

1.0

—

Laparoscopic right hemicolectomy

0.00

0.0

1.0

—

Lesion of plantar nerve

0.00

0.0

1.0

—

Malignant neoplasm of breast, HER-positive

0.88

0.00

1.2

1.0

—

L02BG Aromatase inhibitors

0.98

0.00

1.2

1.0

—

L04AC Interleukin inhibitors

0.00

0.0

1.0

—

Coxibs

0.89

0.00

1.2

—

Other epidermal thickening

0.00

0.0

1.0

—

Muscle strain

0.00

0.0

1.0

—

Medicines for HER+ breast cancer

0.86

0.00

1.2

1.0

—

Amputation of toe

0.00

0.0

1.0

—

L02BX Other hormone antagonists and related agents

0.00

0.0

1.0

—

L01XE Protein kinase inhibitors

0.00

0.0

1.0

—

Disorders of psychological development

0.00

0.0

1.0

—

Decubitus ulcer and pressure area

0.00

0.0

1.0

—

Other sexually transmitted chlamydial diseases

0.00

0.0

1.0

—

0.00

0.0

1.0

—

Pacemaker

0.87

0.00

1.3

1.1

—

Other hearing loss

0.97

0.00

1.2

1.0

—

Paralytic ileus

0.00

0.0

1.0

—

Rubella [German measles]

0.00

0.0

2.0

—

Use of biperiden

0.00

0.0

1.0

—

Alzheimer’s disease (Atypical or mixed)

0.00

0.0

1.0

—

Vascular dementia

0.00

0.0

1.0

—

Nonischemic cardiomyopathy

0.00

0.0

1.0

—

Other ill-defined and unspecified causes of mortality

0.00

0.0

1.0

—

Alzheimer’s disease (Early onset)

0.00

0.0

1.0

—

Dislocation, sprain and strain of joint and ligaments of hip

0.00

0.0

1.0

—

Normal-pressure hydrocephalus

0.00

0.0

1.0

—

Ill-defined and unknown causes of mortality

0.00

0.0

1.0

—

Intrahepatic Cholestasis of Pregnancy (ICP)

0.00

0.0

1.0

—

Pyothorax

0.00

0.0

1.0

—

Systemic atrophies primarily affecting the central nervous system

0.00

0.0

1.0

—

Acute generalized exanthematous pustulosis

0.00

0.0

1.0

—

Calcific aortic valvular stenosis, operated

0.87

0.00

1.0

1.1

—

Other diseases of gallbladder

0.00

0.0

1.0

—

Other eating disorders

0.00

0.0

1.0

—

Toxic effect of contact with venomous animals

0.00

0.0

1.0

—

Other and unspecified coagulation defects

0.00

0.0

1.0

—

KRA_PSY_EATING, excluding more controls

0.00

0.0

1.0

—

Other salmonella infections

0.00

0.0

1.0

—

Dislocation, sprain and strain of joints and ligaments of head

0.00

0.0

1.0

—

Other diseases of peritoneum

0.00

0.0

1.0

—

Calcific aortic valvular stenosis, diagnosis (helper)

0.87

0.00

1.0

1.1

—

Anorexia (incl.atypical)

0.00

0.0

1.0

—

Oligomenorrhoea

0.00

0.0

1.0

—

Follow-up care involving plastic surgery

0.00

0.0

1.0

—

Pediculosis, acariasis and other infestations

0.00

0.0

1.2

—

Unspecified chronic bronchitis

0.00

0.0

1.0

—

Supplementary factors related to causes of morbidity and mortality classified elsewhere

0.85

0.00

1.2

1.1

—

Tobacco use

0.00

0.0

1.0

—

Other pulmonary heart/vessel disease

0.00

0.0

1.0

—

Vitamin deficiency, wide

0.00

0.0

1.0

—

Pregnancy hypertension

1.00

0.00

1.0

—

0.00

0.0

1.0

—

Extracorporeal dialysis

0.00

0.0

1.0

—

Fracture of neck

0.00

0.0

1.0

—

Vascular syndromes of brain in cerebrovascular disorders

0.00

0.0

1.0

—

Autoimmune hyperthyroidism

0.00

0.0

1.0

—

Vitamin deficiency

0.00

0.0

1.0

—

Postpartum haemorrhage due to retained placenta

0.00

0.0

1.0

—

Cysts of oral region, not elsewhere classified

0.00

0.0

1.0

—

Intrahepatic Cholestasis of Pregnancy (ICP) , excluding more controls

0.00

0.0

1.0

—

Maternal care for known or suspected disproportion

0.00

0.0

1.0

—

Operations 2 for CAVS

0.87

0.00

1.0

1.1

—

Non-small cell lung cancer, adenocarcinoma, helper endpoint

0.00

0.0

1.0

—

Type1 diabetes, definitions combined, early onset

0.00

0.0

1.0

—

Conduction disorders

1.00

0.00

1.1

—

Transport accidents

0.97

0.00

1.1

—

Eating disorder

0.00

0.0

1.0

—

Chronic tubulo-interstitial nephritis

0.00

0.0

1.0

—

Sequelae of other and unspecified infectious and parasitic diseases

0.00

0.0

1.1

—

Other specified disorders of muscle

0.00

0.0

1.0

—

Calcific aortic valvular stenosis, including rheumatic fever

0.87

0.00

1.0

1.1

—

Oral leukoplakia and related diseases

0.00

0.0

1.0

—

Open bite

0.00

0.0

1.0

—

Emotional disorders starting during childhood or adolescence

0.00

0.0

1.0

—

Calcific aortic valvular stenosis

0.87

0.00

1.0

1.1

—

Use of selegiline

0.00

0.0

1.0

—

Oesophagitis

0.00

0.0

1.0

—

Specific development disorders of speech and language

0.00

0.0

1.0

—

Trigeminal neuralgia

0.00

0.0

1.0

—

Diseases of tongue

0.00

0.0

1.0

—

Non-small cell lung cancer, adenocarcinoma

0.00

0.0

1.0

—

Chronic kidney disease

1.00

0.00

1.3

1.1

—

Benign neoplasm: Skin of eyelid, including canthus

0.00

0.0

1.0

—

Hypertrophic disorders of skin

0.00

0.0

1.0

—

Colon adenocarcinoma, excluding all cancers (controls excluding all cancers)

0.00

0.0

1.0

—

Lesion of lateral popliteal nerve

0.00

0.0

1.0

—

Other and unspecified abdominal hernia

0.00

0.0

1.0

—

Lesion of sciatic nerve

0.00

0.0

1.0

—

Other neurotic disorders

0.00

0.0

1.0

—

Other and unspecified disease of Bartholin gland

0.00

0.0

1.0

—

Gluteal tendinitis

0.00

0.0

1.0

—

Impingement syndrome of shoulder

0.91

0.00

1.2

1.1

—

Seropositive rheumatoid arthritis

0.86

0.00

1.0

1.1

—

Osteomyelitis

0.00

0.0

1.0

—

Rheumatoid arthritis, including avohilmo

0.98

0.00

1.3

1.1

—

Adrenocortical insufficiency

0.00

0.0

1.0

—

Other obstetric trauma

0.00

0.0

1.0

—

Desensitization to allergens

0.00

0.0

1.0

—

Primary angle-closure glaucoma

0.00

0.0

1.0

—

Haemorrhoids and perianal venous thrombosis

0.98

0.00

1.2

1.1

—

Failed induction of labour

0.00

0.0

1.0

—

Other secondary coxarthrosis

0.00

0.0

1.0

—

Cirrhosis of liver, NAS

0.00

0.0

1.0

—

Infections with a predominantly sexual mode of transmission

0.98

0.00

1.0

1.1

—

Male infertility

0.00

0.0

1.1

—

Colorectal adenocarcinoma, excluding all cancers (controls excluding all cancers)

0.00

0.0

1.0

—

Torsion of ovary, ovarian pedicle and fallopian tube

0.00

0.0

1.0

—

Seropositive rheumatoid arthritis, wide

0.98

0.00

1.0

1.1

—

≡ Risteys

FG R12 + FR

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

HC gene rearrangements [Presence] in Blood or Tissue by Molecular genetics method

Coding

Definition

OMOP mapping QC

Cohort

Year of birth distribution

Age at first measurement

Age at last measurement

Age at start of registry

Duration from first to last measurement

Statistics

Number of measurements over the years

Number of measurements per person

Distribution of lab values

Value range per person

LabWAS