Risteys · K11_OTHABDHER

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — K45, K46 Hospital discharge: ICD-9 — 551[8-9]\|552[8-9]\|553[8-9] Hospital discharge: ICD-8 — 551[8-9] Cause of death: ICD-10 — K45, K46 Cause of death: ICD-9 — 551[8-9]\|552[8-9]\|553[8-9] Cause of death: ICD-8 — 551[8-9] 2 out of 7 registries used, show all original rules.	1494
4. Check minimum number of events None	1494
5. Include endpoints None	1494
6. Filter based on genotype QC (FinnGen only)	1494

	All	Female	Male
Number of individuals
Whole population	11376	6164	5110
Only index persons	9484	5301	4183
Unadjusted period prevalence (%)
Whole population	0.16	0.18	0.14
Only index persons	0.18	0.19	0.16
Median age at first event (years)
Whole population	59.82	61.30	57.99
Only index persons	57.88	59.29	56.11

	All	Female	Male
Number of individuals	1494	838	656
Unadjusted period prevalence (%)	0.29	0.29	0.29
Median age at first event (years)	59.35	57.92	61.18

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
1349: Matched controls
13491

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

K45.8

ICD-10 Finland

Other specified abdominal hernia without obstruction or gangrene

7349.0

323.0

492

K43.9

ICD-10 Finland

Other and unspecified ventral hernia without obstruction or gangrene

385.6

323.0

442

K46.9

ICD-10 Finland

Unspecified abdominal hernia without obstruction or gangrene

1090.3

323.0

390

JAD30

NOMESCO Finland

Repair of incisional hernia using prosthetic material

1205.0

215.7

205

K45.0

ICD-10 Finland

Other specified abdominal hernia with obstruction, without gangrene

+∞

174.9

164

K40.9

ICD-10 Finland

Unilateral or unspecified inguinal hernia, without obstruction or gangrene

80.2

172.3

193

JAB30

NOMESCO Finland

Repair of inguinal hernia using prosthetic material

697.7

130.8

127

6123

FHL

Radical surgery

206.9

128.0

131

K46.0

ICD-10 Finland

Unspecified abdominal hernia with obstruction, without gangrene

1290.1

122.9

118

R10.4

ICD-10 Finland

Other and unspecified abdominal pain

3.6

102.5

667

2865

K42.9

ICD-10 Finland

Umbilical hernia without obstruction or gangrene

74.4

102.3

116

JAD11

NOMESCO Finland

Laparoscopic repair of incisional hernia

+∞

99.2

K43.0

ICD-10 Finland

Incisional hernia with obstruction, without gangrene

950.1

91.9

WX408

NOMESCO Finland

General anesthesy, balanced

3.5

89.0

553

2220

JAD10

NOMESCO Finland

Repair of incisional hernia

450.1

86.1

JN3BD

NOMESCO Finland

Extensive abdominal CT

5.1

84.9

304

731

K44.9

ICD-10 Finland

Diaphragmatic hernia without obstruction or gangrene

27.7

79.6

110

5538X

ICD-9 Finland

Other hernia of abdominal cavity without mention of obstruction or gangrene, Hernia of other specified sites

+∞

71.5

UJF32

NOMESCO Finland

Coloscopy

3.1

68.7

508

2217

JAG00

NOMESCO Finland

Repair of other hernia

647.1

63.4

WX302

NOMESCO Finland

Thoracal epidural anesthesy

6.4

63.4

179

317

55199

ICD-8 Finland

Other hernia of abdominal cavity without mention of obstruction, Of unspecified site

+∞

61.9

K56.6

ICD-10 Finland

Other and unspecified intestinal obstruction

8.9

61.4

136

167

C20.91

ICD-10 Finland

Malignant tumor of the rectum invasive carcinoma

9.5

61.4

131

151

8140/3-C20.9

ICD-O-3

Adenocarcinoma, NOS, of rectum, NOS

10.8

58.1

115

N02AX02

ATC

tramadol; systemic, rectal

2.5

54.2

690

4001

UJD10

NOMESCO Finland

Esophagoscopy, gastroscopy and duodenoscopy

2.7

54.0

482

2293

T81.4

ICD-10 Finland

Infection following a procedure, not elsewhere classified

3.8

52.8

249

752

JAH00

NOMESCO Finland

Laparotomy

9.0

52.5

115

138

55099

ICD-8 Finland

Inguinal hernia without mention of obstruction

+∞

50.3

Z93.3

ICD-10 Finland

Colostomy status

22.6

50.1

JAF10

NOMESCO Finland

Repair of umbilical hernia

41.1

47.3

JAG41

NOMESCO Finland

Repair of stomal hernia, laparoscopic

+∞

47.1

JN3AA

NOMESCO Finland

Abdominal X-ray examination without contrast

6.0

46.0

134

244

JAG96

NOMESCO Finland

Other reconstruction of abdominal wall

101.6

45.1

WX602

NOMESCO Finland

Repeated or continuing anesthesia shots throug a catheter

4.1

44.4

186

501

TPH07

NOMESCO Finland

Cathetrisation of artery

3.5

44.4

229

738

JAF30

NOMESCO Finland

Repair of umbilical hernia using prosthetic material

+∞

44.0

JAH01

NOMESCO Finland

Laparoscopy

6.2

43.7

124

218

B01AB05

ATC

enoxaparin; parenteral

2.4

43.7

516

2785

JFG40

NOMESCO Finland

Revision of enterostomy or colostomy without laparotomy

55.2

40.7

N02BE01

ATC

paracetamol; systemic, rectal

2.8

39.5

1194

9864

JAB11

NOMESCO Finland

Laparoscopic repair of inguinal hernia

140.8

38.9

JN3AD

NOMESCO Finland

Abdominal CT examination

3.8

38.9

178

516

K45.1

ICD-10 Finland

Other specified abdominal hernia with gangrene

+∞

38.7

JFB00

NOMESCO Finland

Partial resection of small intestine

12.7

38.7

QBB10

NOMESCO Finland

Major dressing of wound of skin of trunk

6.3

38.5

107

183

TJF80

NOMESCO Finland

Ostomy education

14.1

38.3

K56.5

ICD-10 Finland

Intestinal adhesions [bands] with obstruction

10.4

37.6

D91

ICPC

Abdominal hernia other

25.9

36.0

K91.4

ICD-10 Finland

Colostomy and enterostomy malfunction

82.4

36.0

GD1AA

NOMESCO Finland

Thorax X-ray examination

2.1

35.6

664

4291

55180

ICD-8 Finland

Other hernia of abdominal cavity without mention of obstruction, Of other specified site

+∞

35.6

UJF45

NOMESCO Finland

Flexible sigmoidoscopy with biopsy

3.3

34.8

191

635

K45

ICD-10 Finland

Other abdominal hernia

345.4

34.1

R10.3

ICD-10 Finland

Pain localized to other parts of lower abdomen

2.5

33.8

309

1424

6124

FHL

Radical cutting and plastic with foreign material

334.8

33.0

JGB30

NOMESCO Finland

Abdominoperineal excision of rectum

27.3

32.9

Y83

ICD-10 Finland

Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

3.6

32.8

160

487

K56.7

ICD-10 Finland

Ileus, unspecified

9.2

31.6

J01MA02

ATC

ciprofloxacin; systemic

2.0

31.5

583

3693

JAG01

NOMESCO Finland

Laparoscopic repair of other hernia

+∞

31.4

JN3AE

NOMESCO Finland

Abdominal ultrasound examination

2.7

31.2

236

972

K43

ICD-10 Finland

Ventral hernia

47.4

30.7

TPH04

NOMESCO Finland

Cathetrisation of vein

2.3

30.1

332

1674

JN4BD

NOMESCO Finland

Extensive body CT

2.8

29.9

218

878

P01AB01

ATC

metronidazole; oral, rectal

2.0

29.7

567

3612

JAP00

NOMESCO Finland

Freeing of adhesions in the peritoneal cavity

11.2

27.9

SPAT1262

SPAT

Handing over of treatment supplies

2.3

27.9

320

1633

WF001

NOMESCO Finland

Preoperative radiotherapy

13.0

27.7

5509B

ICD-9 Finland

Inguinal hernia, without mention of obstruction or gangrene[HERNIA INGUINALIS SINE GANGR/OBSTR,LATERALIS (SCROT]

+∞

27.2

JF1AB

NOMESCO Finland

Passage examination of small bowell with X-ray

10.2

27.1

C20.90

ICD-10 Finland

Malignant tumor of the rectum without histology

7.6

26.9

K42.0

ICD-10 Finland

Umbilical hernia with obstruction, without gangrene

276.2

26.8

A03FA01

ATC

metoclopramide; systemic, rectal

2.2

26.2

332

1766

WX404

NOMESCO Finland

Intravenous generell anesthesy

2.2

26.2

313

1623

T81.3

ICD-10 Finland

Disruption of operation wound, not elsewhere classified

6.9

26.0

100

Z93.2

ICD-10 Finland

Ileostomy status

31.6

26.0

JAG43

NOMESCO Finland

Repair of stomal hernia with mesh

+∞

25.1

A02BC02

ATC

pantoprazole; systemic

1.9

25.0

882

6811

JAG60

NOMESCO Finland

Reconstruction of abdominal wall using prosthetic material

91.8

24.7

S18

ICPC

Laceration/cut

1.9

24.7

585

3943

A02BC05

ATC

esomeprazole; systemic

1.9

24.6

555

3680

WX402

NOMESCO Finland

General anaesthesia

2.3

23.5

237

1126

WZC30

NOMESCO Finland

Teaching

2.4

23.5

216

982

Y83.9

ICD-10 Finland

Surgical procedure, unspecified as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

5.6

23.3

128

N02AA59

ATC

codeine, combinations excl. psycholeptics; systemic

1.8

23.0

627

4397

JAD96

NOMESCO Finland

Other repair of incisional hernia

+∞

23.0

JAP01

NOMESCO Finland

Laparoscopic freeing of adhesions in the peritoneal cavity

10.3

22.9

K40.2

ICD-10 Finland

Bilateral inguinal hernia, without obstruction or gangrene

66.1

22.9

JGB31

NOMESCO Finland

Laparoscopic and perineal excision of rectum

30.6

22.8

WZC00

NOMESCO Finland

Planning of intervention or health care consultation

1.9

22.8

452

2844

J01DB01

ATC

cefalexin; oral

1.9

22.7

1074

9003

JFG50

NOMESCO Finland

Laparotomy with revision of enterostomy or colostomy

233.7

22.7

K57.3

ICD-10 Finland

Diverticular disease of large intestine without perforation or abscess

2.2

22.5

269

1387

QBJ30

NOMESCO Finland

Correction of abdominal apron

16.0

22.4

L01BC06

ATC

capecitabine; oral

4.2

22.0

215

JAG51

NOMESCO Finland

Laparoscopic repair of internal hernia

+∞

21.9

5531A

ICD-9 Finland

Other hernia of abdominal cavity without mention of obstruction or gangrene, Umbilical hernia

+∞

21.9

JAD97

NOMESCO Finland

Other laparoscopic repair of incisional hernia

+∞

21.9

A09

ICD-10 Finland

Other gastroenteritis and colitis of infectious and unspecified origin

2.2

21.8

241

1195

SPAT1125

SPAT

Stoma care and guidance

6.3

21.7

K43.2

ICD-10 Finland

Incisional hernia without obstruction or gangrene

223.4

21.7

A06AD11

ATC

lactulose; oral

2.2

21.6

236

1165

N39.0

ICD-10 Finland

Urinary tract infection, site not specified

2.3

21.2

225

1094

JWA00

NOMESCO Finland

Repair of wound dehiscence in gastroenterological surgery

24.6

20.9

5509A

ICD-9 Finland

Inguinal hernia, without mention of obstruction or gangrene[HERNIA INGUINALIS SINE GANGR/OBSTR,MEDIALIS]

+∞

20.9

JAF11

NOMESCO Finland

Laparoscopic repair of umbilical hernia

+∞

20.9

JAB10

NOMESCO Finland

Repair of inguinal hernia

78.0

20.7

R10.1

ICD-10 Finland

Pain localized to upper abdomen

2.2

20.6

240

1217

N03AX16

ATC

pregabalin; oral

1.9

20.5

338

1975

C03CA01

ATC

furosemide; systemic

1.8

20.4

443

2853

JDF11

NOMESCO Finland

Laparoscopic gastric bypass

9.8

20.4

N02AE01

ATC

buprenorphine; parenteral, sublingual, transdermal

2.3

20.3

212

1019

J01MA12

ATC

levofloxacin; systemic

2.0

20.1

286

1577

E66.8

ICD-10 Finland

Other obesity

3.7

19.9

257

TPH15

NOMESCO Finland

Insertion of central venous catheter through external or internal jugular vein

3.1

19.9

114

390

5539X

ICD-9 Finland

Other hernia of abdominal cavity without mention of obstruction or gangrene, Hernia of unspecified site

+∞

19.8

6125

FHL

Residual surgery, can be reported as a side effect

+∞

19.8

5518X

ICD-9 Finland

Other hernia of abdominal cavity, with gangrene, Hernia of other specified sites, with gangrene

+∞

19.8

JFB60

NOMESCO Finland

Resection of sigmoid colon with end colostomy

15.6

19.8

R03AC02

ATC

salbutamol; inhalant

1.7

19.7

667

4912

6129

FHL

Other measure in this category

106.6

19.6

UKC02

NOMESCO Finland

Cystoscopy

2.1

19.5

252

1335

J01DA01

ATC

[U] cefalexin; systemic

1.7

19.1

825

6492

C20.92

ICD-10 Finland

Malignant tumor of the rectum carcinoma of the adenoma

12.0

18.8

WX704

NOMESCO Finland

Intubation

2.9

18.4

117

429

GD1UA

NOMESCO Finland

Thorax X-ray examination outside radiological department

2.1

18.3

236

1248

WX306

NOMESCO Finland

Lumbar epidural anesthesy

3.2

18.1

311

T81.8

ICD-10 Finland

Other complications of procedures, not elsewhere classified

5.9

17.8

WX110

NOMESCO Finland

Local anesthesy

1.7

17.8

835

6660

5532A

ICD-9 Finland

Other hernia of abdominal cavity without mention of obstruction or gangrene, Ventral hernia [incisional][HERNIA VENTRALIS SINE OBSTRUCTIONE ET GANGRAENA]

+∞

17.7

UJD02

NOMESCO Finland

Gastroscopy

3.5

17.7

255

JEA00

NOMESCO Finland

Appendectomy

3.1

17.7

102

350

XF603

NOMESCO Finland

Direct intraarterial blood pressure measurement

3.8

17.6

204

K21.0

ICD-10 Finland

Gastro-oesophageal reflux disease with oesophagitis

2.5

17.2

142

604

J45.9

ICD-10 Finland

Asthma, unspecified

2.0

17.1

246

1352

M01AE03

ATC

ketoprofen; systemic, rectal

1.7

17.0

513

3603

R10.0

ICD-10 Finland

Acute abdomen

4.4

16.8

143

UJG02

NOMESCO Finland

Proctoscopy

4.9

16.8

116

208

Kela drug reimbursment

Ulcerative colitis and Crohn's disease

3.5

16.7

234

C20.99

ICD-10 Finland

Malignant tumor of the rectum other or unspecified histology

10.5

16.7

JAE10

NOMESCO Finland

Repair of epigastric hernia

+∞

16.7

H02AB06

ATC

prednisolone; systemic

1.6

16.7

613

4540

A02BC03

ATC

lansoprazole; oral

1.7

16.5

393

2569

N03AX12

ATC

gabapentin; oral

2.0

16.4

218

1160

Z71.3

ICD-10 Finland

Dietary counselling and surveillance

3.5

16.4

233

SPAT1263

SPAT

Sampling

1.6

16.2

555

4024

130

Kela drug reimbursment

Malignant tumour

2.4

16.1

147

662

PH2AE

NOMESCO Finland

Ultrasound examination of lower leg veins

2.2

16.0

179

885

WX320

NOMESCO Finland

Spinalanesthesy

1.8

15.9

305

1861

SPAT1255

SPAT

Intravenous administration of medicine

2.7

15.8

115

454

L04AX01

ATC

azathioprine; systemic

3.4

15.8

234

B01AB10

ATC

tinzaparin; parenteral

2.6

15.8

116

464

SPAT1148

SPAT

Treatment of chronic ulcer or burn

2.0

15.7

211

1128

55121

ICD-8 Finland

Other hernia of abdominal cavity without mention of obstruction, Alia hernia ventralis (incisionalis, in cicactrice)

+∞

15.6

K80.2

ICD-10 Finland

Calculus of gallbladder without cholecystitis

2.2

15.6

168

817

A49.9

ICD-10 Finland

Bacterial infection, unspecified

2.2

15.6

169

823

D01

ICPC

Abdominal pain/cramps general

2.4

15.4

135

595

N17.9

ICD-10 Finland

Acute renal failure, unspecified

3.4

15.3

229

K57.2

ICD-10 Finland

Diverticular disease of large intestine with perforation and abscess

5.0

15.3

101

N10

ICD-10 Finland

Acute tubulo-interstitial nephritis

2.1

15.2

192

1001

JN3CD

NOMESCO Finland

Abdominal CT examination both without and with contrast

3.4

15.1

226

T81.0

ICD-10 Finland

Haemorrhage and haematoma complicating a procedure, not elsewhere classified

2.9

15.1

352

JN1AE

NOMESCO Finland

Ultrasound examination of upper part of abdomen

2.4

15.0

134

595

203

Kela drug reimbursment

Chronic asthma and similar chronic obstructive pulmonary diseases

1.9

14.9

262

1545

K50.1

ICD-10 Finland

Crohn disease of large intestine

8.4

14.8

K50.9

ICD-10 Finland

Crohn disease, unspecified

6.9

14.7

A07EC02

ATC

mesalazine; oral, rectal

3.0

14.7

315

X59

ICD-10 Finland

Exposure to unspecified factor

1.9

14.6

237

1357

SPAT1153

SPAT

Removal of sutures

1.7

14.6

432

2990

GD1QA

NOMESCO Finland

Supine thorax X-ray examination

1.9

14.3

234

1345

WX700

NOMESCO Finland

Respiratory and circulatory monitoring

1.9

14.3

225

1274

Z01.8

ICD-10 Finland

Other specified special examinations

1.8

14.0

283

1748

A03FA02

ATC

cisapride; oral, rectal

2.4

13.9

127

568

D37.5

ICD-10 Finland

Neoplasm of uncertain or unknown behaviour: Rectum

8.3

13.8

N02AA05

ATC

oxycodone; systemic

1.9

13.8

221

1261

K51.9

ICD-10 Finland

Ulcerative colitis, unspecified

3.9

13.8

147

K59.09

ICD-10 Finland

Constipation, unspecified

2.7

13.7

391

K43.1

ICD-10 Finland

Incisional hernia with gangrene

+∞

13.6

5509D

ICD-9 Finland

Inguinal hernia, without mention of obstruction or gangrene[HERNIA INGUINALIS SINE GANGR/OBSTR,RECIDIVANS]

+∞

13.6

A06AC01

ATC

ispaghula (psylla seeds); oral

1.7

13.4

323

2100

SPAT1254

SPAT

Administration of medicine

1.9

13.4

216

1234

K50.8

ICD-10 Finland

Other Crohn disease

6.3

13.4

C20

ICD-10 Finland

Malignant neoplasm of rectum

7.1

13.4

R11

ICD-10 Finland

Nausea and vomiting

2.4

13.4

116

508

Z93

ICD-10 Finland

Artificial opening status

21.4

13.3

R4110

NOMESCO Finland

Physiotherapy

1.7

13.3

344

2282

M54.5

ICD-10 Finland

Low back pain

1.6

13.2

393

2704

K46

ICD-10 Finland

Unspecified abdominal hernia

40.5

13.2

ZX120

NOMESCO Finland

Intravenous

2.2

13.1

141

682

J01DA09

ATC

[U] cefadroxil; inhalant, oral

1.7

13.1

348

2322

RD210

NOMESCO Finland

5.3

13.1

KBJ10

NOMESCO Finland

Cutaneous ureteroenterostomy

9.4

13.0

JFF23

NOMESCO Finland

Transversostomy

7.0

12.9

R06.0

ICD-10 Finland

Dyspnoea

1.7

12.8

333

2205

M79.6

ICD-10 Finland

Pain in limb

1.6

12.8

441

3151

QBB05

NOMESCO Finland

Revision of wound of skin of trunk

7.3

12.8

JA1AE

NOMESCO Finland

Ultrasound examination of groin and abdominal wall

6.1

12.7

TPH20

NOMESCO Finland

Insertion of central venous catheter through subclavian or brachiocephalic vein

3.7

12.7

158

JKA20

NOMESCO Finland

Cholecystectomy

3.7

12.7

158

FB1BD

NOMESCO Finland

Extensive CT examination of arteria pulmonalis

2.3

12.7

117

529

SPAT1144

SPAT

Treatment of reopened or infected surgical wound

2.3

12.6

116

524

K46.1

ICD-10 Finland

Unspecified abdominal hernia with gangrene

+∞

12.5

D99

ICPC

Disease digestive system other

7.4

12.5

A02BC01

ATC

omeprazole; systemic

1.6

12.5

364

2488

UJF12

NOMESCO Finland

Enteroscopy through intestinal stoma

24.5

12.5

K44.0

ICD-10 Finland

Diaphragmatic hernia with obstruction, without gangrene

131.1

12.5

J01FA06

ATC

roxithromycin; oral

1.6

12.4

510

3796

R07.4

ICD-10 Finland

Chest pain, unspecified

1.6

12.4

351

2378

TKC20

NOMESCO Finland

Catheterisation of bladder

2.4

12.4

109

480

D75

ICPC

Malignant neoplasm colon/rectum

8.1

12.3

E66.9

ICD-10 Finland

Obesity, unspecified

3.5

12.3

163

T81.9

ICD-10 Finland

Unspecified complication of procedure

5.2

12.2

TJD00

NOMESCO Finland

Insertion of nasogastric or naso-gastroduodenal tube

5.9

12.1

K51.5

ICD-10 Finland

Left sided colitis

4.0

12.1

124

R51.80

ICD-10 Finland

Headache

2.0

12.1

171

927

N02AJ06

ATC

codeine and paracetamol; systemic

1.6

12.1

434

3125

M01AB05

ATC

diclofenac; systemic, rectal

1.5

12.0

816

6785

K63.1

ICD-10 Finland

Perforation of intestine (nontraumatic)

7.6

11.9

C07AB07

ATC

bisoprolol; oral

1.5

11.9

625

4904

R50.9

ICD-10 Finland

Fever, unspecified

1.9

11.9

181

1010

SPAT1301

SPAT

No procedures

1.6

11.8

414

2961

JG1BG

NOMESCO Finland

MRI of rectum

8.5

11.8

D06

ICPC

Abdominal pain localized other

2.4

11.8

101

441

JN4AD

NOMESCO Finland

Body CT examination

2.2

11.7

120

567

J01CR02

ATC

amoxicillin and beta-lactamase inhibitor; systemic

1.5

11.7

605

4727

KH1AE

NOMESCO Finland

Urinary tract ultrasound examination

2.5

11.7

384

WX892

NOMESCO Finland

Monitored bed care

2.3

11.7

110

500

JFH10

NOMESCO Finland

Total colectomy and ileostomy

30.3

11.6

SPAT1230

SPAT

Aid fitting and borrowing and monitoring of use

1.8

11.6

234

1435

WX002

NOMESCO Finland

Sedation and analgesia

1.7

11.6

251

1571

JAG97

NOMESCO Finland

Other laparoscopic reconstruction of abdominal wall

121.0

11.4

J01EE02

ATC

sulfadiazine and trimethoprim; systemic

1.6

11.4

314

2106

K51.1

ICD-10 Finland

Ulcerative (chronic) ileocolitis

7.9

11.4

JFG10

NOMESCO Finland

Closure of loop colostomy without resection

7.0

11.3

WZB00

NOMESCO Finland

Telephone receipt or other advice

1.6

11.3

331

2253

QX2XE

NOMESCO Finland

Ultrsound examination of soft tissue not elsewhere classified

3.5

11.3

148

A12AX

ATC

Calcium, combinations with vitamin D and/or other drugs

1.5

11.2

444

3259

K56.0

ICD-10 Finland

Paralytic ileus

6.9

11.2

Y83.8

ICD-10 Finland

Other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

4.1

11.2

104

XF400

NOMESCO Finland

ECG with 12 standard connections

1.8

11.1

223

1367

J01EA01

ATC

trimethoprim; systemic

1.6

11.0

331

2270

FM1EE

NOMESCO Finland

Extensive structural and functional ultrasound examination of heart

1.7

10.9

282

1856

L28

ICPC

Limited function/disability (L)

1.8

10.8

218

1335

H02AB04

ATC

methylprednisolone; systemic

1.8

10.8

186

1081

E66.01

ICD-10 Finland

Obesity due to excess calories

2.3

10.8

445

Z04.8

ICD-10 Finland

Examination and observation for other specified reasons

1.9

10.8

152

825

J01AA02

ATC

doxycycline; systemic

1.5

10.7

995

8740

R03AC12

ATC

salmeterol; inhalant

2.7

10.6

270

JFG00

NOMESCO Finland

Closure of loop enterostomy without resection

9.3

10.5

G47.3

ICD-10 Finland

Sleep apnoea

1.7

10.4

254

1644

K43.5

ICD-10 Finland

Parastomal hernia without obstruction or gangrene

+∞

10.4

JAE11

NOMESCO Finland

Laparoscopic repair of epigastric hernia

+∞

10.4

M25.5

ICD-10 Finland

Pain in joint

1.6

10.4

327

2266

A07EA02

ATC

hydrocortisone; rectal

3.7

10.3

122

R03AC03

ATC

terbutaline; inhalant

1.8

10.3

173

998

A02BA02

ATC

ranitidine; systemic

1.7

10.3

260

1700

JFK10

NOMESCO Finland

Freeing of adhesions in intestinal obstruction

13.2

10.2

JGB00

NOMESCO Finland

Partial proctectomy and colorectal or coloanal anastomosis

10.1

10.0

J18.9

ICD-10 Finland

Pneumonia, unspecified

1.6

10.0

312

2152

WX882

NOMESCO Finland

High dependency care

3.5

10.0

131

J01CA04

ATC

amoxicillin; systemic

1.5

10.0

978

8604

JFF26

NOMESCO Finland

Sigmoidostomy

40.4

10.0

SPAT1149

SPAT

Suture or treatment of traumatic wound

1.8

10.0

177

1038

SPAT1249

SPAT

Treatment-related counselling outside office

1.5

10.0

485

3705

SPAT1253

SPAT

Initiation, adjustment, discontinuation or repetition of medication

1.5

9.9

391

2847

GD1PA

NOMESCO Finland

X-ray examination of the lungs in one projection

2.0

9.7

124

649

J15.9

ICD-10 Finland

Bacterial pneumonia, unspecified

2.0

9.7

121

624

M01AH01

ATC

celecoxib; oral (coxibs)

1.7

9.6

233

1504

R07.3

ICD-10 Finland

Other chest pain

2.0

9.6

121

628

7890A

ICD-9 Finland

Other symptoms involving abdomen and pelvis, Abdominal pain

2.5

9.6

324

I26.9

ICD-10 Finland

Pulmonary embolism without mention of acute cor pulmonale

2.3

9.5

373

L02.2

ICD-10 Finland

Cutaneous abscess, furuncle and carbuncle of trunk

2.8

9.5

213

D50.9

ICD-10 Finland

Iron deficiency anaemia, unspecified

2.2

9.5

100

480

EB1HA

NOMESCO Finland

Panorama tomography of teeth and jaws or similar X-ray examination

1.5

9.5

458

3485

JKA21

NOMESCO Finland

Laparoscopic cholecystectomy

1.9

9.4

139

765

JG1CG

NOMESCO Finland

Extensive MRI of rectum

7.6

9.4

A41.9

ICD-10 Finland

Sepsis, unspecified

2.8

9.4

216

55110

ICD-8 Finland

Other hernia of abdominal cavity without mention of obstruction, Umbilical

+∞

9.4

A07EA06

ATC

budesonide; oral, local oral

3.1

9.4

166

F32.2

ICD-10 Finland

Severe depressive episode without psychotic symptoms

2.5

9.3

305

K66.0

ICD-10 Finland

Peritoneal adhesions

10.7

9.3

K40

ICD-10 Finland

Inguinal hernia

9.6

9.3

NA3BG

NOMESCO Finland

Lumbar spine MRI examination with high intensity magnet

2.0

9.3

122

642

K50.0

ICD-10 Finland

Crohn disease of small intestine

5.3

9.2

J45.0

ICD-10 Finland

Predominantly allergic asthma

2.1

9.2

101

495

G04CA02

ATC

tamsulosin; oral

1.6

9.1

281

1928

K21.9

ICD-10 Finland

Gastro-oesophageal reflux disease without oesophagitis

2.0

9.1

111

569

N05CF01

ATC

zopiclone; oral

1.5

9.1

416

3122

NA3AA

NOMESCO Finland

Lumbar spine X-ray examination without contrast

2.0

9.1

121

642

K52.9

ICD-10 Finland

Noninfective gastroenteritis and colitis, unspecified

2.8

9.1

209

K65.0

ICD-10 Finland

Acute peritonitis

5.4

9.1

JFF10

NOMESCO Finland

Loop enterostomy

8.4

9.1

M17.1

ICD-10 Finland

Other primary gonarthrosis

1.6

9.1

272

1855

WX290

NOMESCO Finland

Other blockade of nerve

1.5

9.1

448

3418

QBE15

NOMESCO Finland

Excision of other superficial lesion of skin of trunk

9.1

9.0

JAH33

NOMESCO Finland

Opening of laparostomy

36.9

9.0

601

Kela drug reimbursment

Severe malabsorption of nutrients, mainly fats

6.6

9.0

K40.3

ICD-10 Finland

Unilateral or unspecified inguinal hernia, with obstruction, without gangrene

24.2

8.9

JFF30

NOMESCO Finland

Other colostomy

24.2

8.9

R42

ICD-10 Finland

Dizziness and giddiness

1.6

8.9

273

1873

B01AB04

ATC

dalteparin; parenteral

2.4

8.9

313

I10

ICD-10 Finland

Essential (primary) hypertension

1.4

8.8

753

6363

QBA10

NOMESCO Finland

Incision of skin of trunk

5.2

8.8

R33

ICD-10 Finland

Retention of urine

2.0

8.8

111

579

M54.9

ICD-10 Finland

Dorsalgia, unspecified

1.9

8.7

133

741

R03AK06

ATC

salmeterol and fluticasone; inhalant

1.7

8.7

173

1055

EB1AA

NOMESCO Finland

Tooth X-ray examination

1.4

8.7

614

5006

J01FF01

ATC

clindamycin; systemic

1.5

8.6

341

2479

N02AC04

ATC

dextropropoxyphene; oral

2.5

8.6

256

M01AC06

ATC

meloxicam; systemic, rectal

1.4

8.5

446

3432

LC2BE

NOMESCO Finland

Transvaginal ultrasound examination of uterus, parametria and lower abdomen

1.6

8.5

270

1861

Z43.2

ICD-10 Finland

Attention to ileostomy

27.7

8.5

M03BX02

ATC

tizanidine; oral

1.4

8.4

707

5933

X57

ICD-10 Finland

Unspecified privation

3.5

8.4

112

SPAT1083

SPAT

Initiation and monitoring of IV fluid therapy

2.4

8.4

282

SPAT1306

SPAT

Counselling and guidance related to nutrition and weight management

1.7

8.4

178

1105

J20.9

ICD-10 Finland

Acute bronchitis, unspecified

1.6

8.4

213

1388

JAG46

NOMESCO Finland

Repair of recurrent stomal hernia, laparoscopic

+∞

8.3

ZXA05

NOMESCO Finland

Left side

1.5

8.3

317

2281

JFB46

NOMESCO Finland

Resection of sigmoid colon

4.4

8.3

K56.2

ICD-10 Finland

Volvulus

7.6

8.2

R03BA02

ATC

budesonide; inhalant

1.6

8.2

205

1332

K02.1

ICD-10 Finland

Caries of dentine

1.4

8.1

613

5036

JFH20

NOMESCO Finland

Proctocolectomy and ileostomy

33.5

8.1

TKC22

NOMESCO Finland

Catheterisation instruction

3.2

8.1

127

D01AC02

ATC

miconazole; topical

2.0

8.1

103

538

M02AA07

ATC

piroxicam; topical

1.4

8.0

460

3591

A46

ICD-10 Finland

Erysipelas

1.7

8.0

186

1184

SPAT1325

SPAT

Vaccination

1.4

8.0

441

3413

F32.9

ICD-10 Finland

Depressive episode, unspecified

1.9

8.0

124

695

S06.0

ICD-10 Finland

Concussion

1.9

8.0

122

680

M01AH05

ATC

etoricoxib; oral

1.4

7.9

672

5622

5742A

ICD-9 Finland

Cholelithiasis, Calculus of gallbladder without mention of cholecystitis[CHOLECYSTOLITHIASIS SINE CHOLECYSTITIDE,SINE OBSTR]

3.0

7.9

146

B03BA03

ATC

hydroxocobalamin; parenteral

2.2

7.9

393

J01CA08

ATC

pivmecillinam; oral

1.4

7.8

458

3590

A41.0

ICD-10 Finland

Sepsis due to Staphylococcus aureus

3.6

7.8

T36

ICD-10 Finland

Poisoning by systemic antibiotics

2.8

7.8

180

H02AB07

ATC

prednisone; oral

1.7

7.8

177

1122

Z93.8

ICD-10 Finland

Other artificial opening status

45.2

7.7

L30.9

ICD-10 Finland

Dermatitis, unspecified

1.6

7.7

208

1378

WX105

NOMESCO Finland

Surface analgesia on skin or mucosa

1.9

7.6

104

560

TPX10

NOMESCO Finland

Implantation of vascular injection port

2.9

7.6

155

JFA70

NOMESCO Finland

Suture of small intestine

11.9

7.6

JAB00

NOMESCO Finland

Division and ligature of inguinal hernia sac

25.1

7.6

JFG36

NOMESCO Finland

Closure of terminal colostomy with anastomosis to rectum

25.1

7.6

M51.1

ICD-10 Finland

Lumbar and other intervertebral disc disorders with radiculopathy

1.7

7.5

165

1031

XF600

NOMESCO Finland

Bloodpressure measurement

2.1

7.5

418

R03DC03

ATC

montelukast; oral

1.7

7.4

175

1116

JAG50

NOMESCO Finland

Repair of internal hernia

80.5

7.4

JGB36

NOMESCO Finland

Wide excision of rectum

80.5

7.4

K41.9

ICD-10 Finland

Unilateral or unspecified femoral hernia, without obstruction or gangrene

80.5

7.4

D64.9

ICD-10 Finland

Anaemia, unspecified

1.8

7.4

130

762

N06AA09

ATC

amitriptyline; systemic

1.8

7.4

128

746

J02AC01

ATC

fluconazole; systemic

1.4

7.4

434

3390

AA1AD

NOMESCO Finland

CT of head and brain

1.5

7.4

299

2175

R52.0

ICD-10 Finland

Acute pain

2.9

7.3

153

K30

ICD-10 Finland

Functional dyspepsia

1.8

7.3

120

686

U07

ICPC

Urine symptom/complaint other

2.1

7.3

366

5509X

ICD-9 Finland

Inguinal hernia, without mention of obstruction or gangrene[HERNIA INGUINALIS SINE GANGR/OBSTR,ALIA SEU NUD]

+∞

7.3

5530A

ICD-9 Finland

Other hernia of abdominal cavity without mention of obstruction or gangrene, Femoral hernia

+∞

7.3

JAG47

NOMESCO Finland

Repair of recurrent stomal hernia with mesh

+∞

7.3

JBB01

NOMESCO Finland

Laparoscopic repair of paraoesophageal hernia

+∞

7.3

5512A

ICD-9 Finland

Other hernia of abdominal cavity, with gangrene, Ventral hernia with gangrene[HERNIA VENTRALIS CUM GANGRAENA]

+∞

7.3

G56.0

ICD-10 Finland

Carpal tunnel syndrome

1.7

7.3

155

960

SPAT1256

SPAT

Intramuscular and subcutaneous injection

1.4

7.3

508

4094

TK800

NOMESCO Finland

Hemodialysis

3.4

7.2

KCC30

NOMESCO Finland

Cystectomy with excision of female internal genital organs

15.8

7.2

N06AX21

ATC

duloxetine; oral

1.8

7.2

119

680

J45.1

ICD-10 Finland

Nonallergic asthma

2.0

7.2

461

K62.5

ICD-10 Finland

Haemorrhage of anus and rectum

2.2

7.2

314

SAA01

NOMESCO Finland

Simple examination of mouth

1.4

7.2

779

6744

K59.1

ICD-10 Finland

Functional diarrhoea

2.3

7.2

282

SPAT1137

SPAT

Taking care of patient’s/customer’s hygiene

2.0

7.2

426

Z71.8

ICD-10 Finland

Other specified counselling

1.5

7.1

255

1802

R05

ICD-10 Finland

Cough

1.5

7.1

226

1553

I25.1

ICD-10 Finland

Atherosclerotic heart disease

1.5

7.1

280

2021

G40.9

ICD-10 Finland

Epilepsy, unspecified

2.7

7.1

181

XX3DW

NOMESCO Finland

Time consuming IT work

1.8

7.1

132

785

WX610

NOMESCO Finland

Patient controlled analgesia

8.0

7.1

M03BA52

ATC

carisoprodol, combinations excl. psycholeptics; oral

2.4

7.1

236

F33.9

ICD-10 Finland

Recurrent depressive disorder, unspecified

2.8

7.1

151

JN2AE

NOMESCO Finland

Ultrasound examination of lower part of abdomen without contrast

4.6

7.1

Y60

ICD-10 Finland

Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care

5.3

7.1

JH1CG

NOMESCO Finland

Extensive MRI of perianal area

10.1

7.0

SPAT1250

SPAT

Comprehensive monitoring of chronic illness

1.4

7.0

356

2703

WX872

NOMESCO Finland

Intensive care

2.3

7.0

291

N30.0

ICD-10 Finland

Acute cystitis

1.6

7.0

165

1054

C64.88

ICD-10 Finland

Other malignant neoplasm of kidney, except renal pelvis

3.2

7.0

113

N39.4

ICD-10 Finland

Other specified urinary incontinence

1.9

7.0

104

575

Z03.9

ICD-10 Finland

Observation for suspected disease or condition, unspecified

1.6

7.0

203

1369

X69

ICD-10 Finland

Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances

3.1

6.9

114

QBG20

NOMESCO Finland

Operation for chronic ulcer or fistula of skin of trunk

13.8

6.9

A28

ICPC

Limited function/disability NOS

1.6

6.9

186

1230

NA1AD

NOMESCO Finland

Cervical spine CT examination

2.5

6.9

216

N06AB03

ATC

fluoxetine; oral

1.7

6.9

148

923

K59.0

ICD-10 Finland

Constipation

2.1

6.8

383

N02AB03

ATC

fentanyl; nasal, sublingual, transdermal

2.2

6.8

302

R06AE07

ATC

cetirizine; oral

1.4

6.8

484

3899

WYA30

NOMESCO Finland

Preparations for expected poor cooperation

1.9

6.7

532

A01AB09

ATC

miconazole; local oral

1.8

6.7

115

666

JFF27

NOMESCO Finland

Laparoscopic sigmoidostomy

16.8

6.7

MCA10

NOMESCO Finland

Lower uterine segment caesarean section

2.2

6.7

317

UJF30

NOMESCO Finland

Ileoscopy through colon

1.8

6.7

113

651

C10AC01

ATC

colestyramine; oral

2.8

6.7

145

K55.0

ICD-10 Finland

Acute vascular disorders of intestine

7.2

6.7

R03BA05

ATC

fluticasone; inhalant

1.6

6.7

203

1381

N18.9

ICD-10 Finland

Chronic kidney disease, unspecified

2.0

6.7

407

Z08.0

ICD-10 Finland

Follow-up examination after surgery for malignant neoplasm

3.2

6.7

106

6435

FHL

Abdominoperineal resection and colostomy

22.6

6.7

A02BA04

ATC

nizatidine; systemic

1.9

6.6

544

JN2CG

NOMESCO Finland

Extensive MRI examination of lower part of abdoment with high intensity magnet

3.6

6.6

TPH30

NOMESCO Finland

Insertion of central venous catheter through periferal vein

3.9

6.6

N03AE01

ATC

clonazepam; systemic

2.1

6.6

375

R05FA02

ATC

opium derivatives and expectorants; systemic

1.4

6.6

471

3795

JFF13

NOMESCO Finland

Terminal enterostomy

12.3

6.6

JF1AD

NOMESCO Finland

Small bowel CT

8.7

6.6

F32.10

ICD-10 Finland

Moderate depressive episode without somatic syndrome

2.0

6.5

404

J69.0

ICD-10 Finland

Pneumonitis due to food and vomit

3.4

6.5

Z43.3

ICD-10 Finland

Attention to colostomy

10.1

6.5

Z00.4

ICD-10 Finland

General psychiatric examination, not elsewhere classified

2.0

6.5

448

WYA05

NOMESCO Finland

Emergency visit or other similar visit involving procedures

1.4

6.5

517

4232

WX725

NOMESCO Finland

Noninvasive ventilation

2.2

6.5

295

J01DA06

ATC

[U] cefuroxime; systemic

1.6

6.5

167

1091

K57.9

ICD-10 Finland

Diverticular disease of intestine, part unspecified, without perforation or abscess

3.1

6.4

109

SPAT1223

SPAT

Implementation of physical therapy rehabilitation plan

1.4

6.4

353

2714

M54

ICD-10 Finland

Dorsalgia

1.7

6.4

118

703

J20

ICD-10 Finland

Acute bronchitis

1.8

6.4

109

632

JAH30

NOMESCO Finland

Laparostomy

70.1

6.4

S97

ICPC

Chronic ulcer skin

2.0

6.4

375

Z09.0

ICD-10 Finland

Follow-up examination after surgery for other conditions

1.9

6.4

491

N06AB04

ATC

citalopram; systemic

1.5

6.4

247

1774

K29.7

ICD-10 Finland

Gastritis, unspecified

2.6

6.4

180

C01DA08

ATC

isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal

1.4

6.3

291

2161

JF1BD

NOMESCO Finland

Very extensive small bowel CT

6.6

6.3

D29

ICPC

Digestive symptom/complaint other

3.4

6.3

JA2AT

NOMESCO Finland

Abdominal puncture with ultrasound guidance

5.2

6.3

K92.2

ICD-10 Finland

Gastrointestinal haemorrhage, unspecified

2.7

6.3

146

SFA10

NOMESCO Finland

Fillning on one surface of tooth

1.3

6.3

565

4709

M79.1

ICD-10 Finland

Myalgia

1.7

6.3

142

896

T82

ICPC

Obesity

2.6

6.3

174

A04

ICPC

Weakness/tiredness general

1.6

6.3

150

964

JFG26

NOMESCO Finland

Closure of terminal enterostomy with anastomosis to colon

+∞

6.3

K43.3

ICD-10 Finland

Parastomal hernia with obstruction, without gangrene

+∞

6.3

A01

ICPC

Pain general/multiple sites

1.9

6.2

502

X58

ICD-10 Finland

Exposure to other specified factors

1.6

6.2

145

923

NGB20

NOMESCO Finland

Primary total prosthetic replacement of knee joint without patellar part

1.7

6.2

129

794

JWW96

NOMESCO Finland

Other reoperation in gastroenterological surgery

26.8

6.2

K91.2

ICD-10 Finland

Postsurgical malabsorption, not elsewhere classified

26.8

6.2

YL1BD

NOMESCO Finland

Extensive CT examination of pelvis for dose design of radiotherapy

3.0

6.2

112

I48

ICD-10 Finland

Atrial fibrillation and flutter

1.4

6.2

287

2137

ZXA10

NOMESCO Finland

Bilateral

1.5

6.2

221

1557

A04.7

ICD-10 Finland

Enterocolitis due to Clostridium difficile

2.8

6.2

135

SPAT1222

SPAT

Counselling/guidance promoting independent living

1.5

6.2

186

1263

M17.0

ICD-10 Finland

Primary gonarthrosis, bilateral

1.6

6.1

165

1089

56310

ICD-8 Finland

Chronic enteritis and ulcerative colitis, Ulcerative colitis

7.7

6.1

205

Kela drug reimbursment

Chronic hypertension

1.4

6.1

363

2824

A03CA02

ATC

clidinium and psycholeptics; oral

2.0

6.1

410

R4190

NOMESCO Finland

Nutritional therapy

2.7

6.1

143

SPAT1260

SPAT

Consultation of another employee

1.5

6.1

213

1496

K51.8

ICD-10 Finland

Other ulcerative colitis

3.9

6.1

A04AA01

ATC

ondansetron; systemic, rectal

1.9

6.1

455

5562A

ICD-9 Finland

Idiopathic proctocolitis, Ulcerative (chronic) proctitis

12.6

6.1

SPAT1312

SPAT

General health counselling

1.4

6.1

360

2802

E11.9

ICD-10 Finland

Type 2 diabetes mellitus, without complications

1.4

6.1

300

2262

G44.2

ICD-10 Finland

Tension-type headache

1.6

6.0

137

868

U76

ICPC

Malignant neoplasm of bladder

10.1

6.0

M54.4

ICD-10 Finland

Lumbago with sciatica

1.6

6.0

173

1163

D18

ICPC

Change in faeces/bowel movements

2.9

6.0

115

A08.4

ICD-10 Finland

Viral intestinal infection, unspecified

2.8

6.0

132

NAME	K11_OTHABDHER
CONTROL_EXCLUDE	K11_HERNIA
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	K4[5-6]
HD_ICD_9	551[8-9]\|552[8-9]\|553[8-9]
HD_ICD_8	551[8-9]
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	K4[5-6]
COD_ICD_9	551[8-9]\|552[8-9]\|553[8-9]
COD_ICD_8	551[8-9]
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Parameter	HR [95% CI]	p-value
K11_OTHABDHER	1.483 [1.31, 1.68]	< 0.001
Birth year	0.992 [0.98, 1.0]	0.067

Parameter	HR [95% CI]	p-value
K11_OTHABDHER	1.544 [1.35, 1.77]	< 0.001
Birth year	0.983 [0.97, 0.99]	< 0.001

N-year risk	Females	Males
1	0.122%	0.25%
5	0.813%	1.527%
10	2.132%	3.895%
15	3.966%	7.384%
20	6.631%	12.183%

Other and unspecified abdominal hernia

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints