Risteys ·

OMOP concept ID	Test name	Measurement unit (harmonized unit)	N people	N records	Missing measurement value	Harmonized value distribution	Test outcome NA N A AA L LL H HH
3050129	s-tr1seul	— (—)	17347	24971	100.00%	Distribution not available

LabWAS

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

Failed induction of labour

911

2484

5.07

319.09

1.5

1.4

—

Obstructed labour due to malposition and malpresentation of fetus

1607

5492

3.02

316.40

1.4

—

Postpartum care and examination

1522

588

20.41

307.65

1.5

—

Contraceptive management

911

595

11.14

307.65

1.5

—

Maternal care for known or suspected abnormality of pelvic organs

2382

4593

4.10

307.65

1.6

1.3

—

Single delivery by caesarean section

1977

697

20.44

307.65

1.4

1.1

—

Other maternal disorders predominantly related to pregnancy

4188

8953

3.23

307.65

1.5

1.4

—

Other obstetric conditions, not elsewhere classified

4685

11093

3.30

307.65

1.5

1.4

—

Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium

4700

11088

3.32

307.65

1.5

1.4

—

Diabetes mellitus in pregnancy

3809

8794

3.26

307.65

1.5

1.4

—

Maternal care related to the fetus and amniotic cavity and possible delivery problems

3580

5078

4.69

307.65

1.5

1.3

—

Maternal care for other known or suspected fetal problems

2931

4968

4.56

307.65

1.6

1.3

—

Single delivery by forceps and vacuum extractor

1933

688

22.53

307.65

1.5

1.1

—

Prolonged pregnancy

1922

4645

4.48

307.65

1.4

1.3

—

Antenatal screening

2278

603

25.82

307.65

1.4

1.5

—

Supervision of normal pregnancy

1972

599

22.41

307.65

1.4

1.5

—

Perineal laceration during delivery

2805

6184

5.17

307.65

1.5

1.4

—

False labour

2965

5010

4.30

307.65

1.6

1.3

—

Single spontaneous delivery

2498

724

20.69

307.65

1.5

1.1

—

Maternal care for known or suspected malpresentation of fetus

1962

4421

3.79

307.65

1.5

1.3

—

Complications of labour and delivery

4190

6617

3.88

307.65

1.5

1.4

—

Maternal care for known or suspected fetal abnormality and damage

1900

4358

4.63

307.65

1.5

1.3

—

Supervision of high-risk pregnancy

1745

589

21.10

307.65

1.6

1.5

—

Other complications of labour and delivery, not elsewhere classified

2196

5709

5.11

307.65

1.4

—

Postpartum haemorrhage

2592

6178

4.17

307.65

1.6

1.4

—

Premature rupture of membranes

2472

4755

4.50

307.65

1.6

1.3

—

Procreative management

1364

580

21.15

307.65

1.5

—

Labour and delivery complicated by fetal stress [distress]

3033

6214

3.89

307.65

1.5

1.4

—

Gestational diabetes (for exclusion)

4174

12267

2.74

307.65

1.5

1.4

—

Delivery

2603

725

21.56

307.65

1.4

1.1

—

Delivery, wide proxy

2497

200

77.38

307.65

1.4

1.1

—

Other disorders of amniotic fluid and membranes

1389

4175

3.85

307.65

1.5

1.3

—

Pregnancy, childbirth and the puerperium

1983

276.23

307.65

1.4

1.0

—

Pregnancy examination and test

1715

589

22.55

307.65

1.5

—

Persons encountering health services in circumstances related to reproduction

1953

605

23.04

307.65

1.4

1.5

—

Long labour

2051

5851

3.41

307.65

1.4

—

Outcome of delivery

1732

581

22.87

307.65

1.3

1.5

—

Abnormal findings on antenatal screening of mother

1341

4912

3.62

294.24

1.7

1.4

—

Postpartum hemorraghe, all women as controls

2592

12924

2.22

254.95

1.6

1.4

—

Factors influencing health status and contact with health services

407

234

8.87

222.68

1.4

1.5

—

Spontaneous abortion

2683

9992

1.91

179.73

1.6

1.4

—

Antepartum haemorrhage, not elsewhere classified

708

2291

3.55

179.67

1.6

1.3

—

Maternal care for other conditions predominantly related to pregnancy

1643

7800

2.26

177.98

1.5

1.4

—

Multiple delivery

233

296

8.37

172.86

1.5

1.1

—

Other abnormal products of conception

2574

9631

1.90

163.73

1.6

1.4

—

Female infertility

2578

8882

1.90

159.82

1.4

—

Female infertility, cervical, vaginal, other or unspecified origin

2343

8479

1.94

157.14

1.4

—

Infections of genitourinary tract in pregnancy

818

3211

2.92

146.86

1.7

1.4

—

Any operation in hilmo

141

57.57

139.51

1.4

1.5

—

Complications predominantly related to the puerperium

1842

10202

1.94

134.63

1.5

1.4

—

Use of hypnotics and sedatives

836

10943

0.43

125.88

1.4

—

Persons encountering health services for specific procedures and health care

1279

14887

0.51

122.21

1.4

—

Pregnancy with abortive outcome

3251

10814

1.62

120.31

1.6

1.4

—

Polyhydramnios

434

1374

3.75

116.05

1.6

1.3

—

Statin medication

384

6522

0.33

110.33

1.4

—

Retained placenta and membranes, without haemorrhage

466

1549

3.20

109.14

1.6

1.4

—

Special screening examination for infectious and parasitic diseases

1719

7164

1.86

108.61

1.5

1.4

—

Haemorrhage in early pregnancy

1365

7101

1.97

108.17

1.6

1.4

—

Preterm labour and delivery

814

3592

2.36

106.59

1.5

1.4

—

Sleep apnoea, including avohilmo

459

7753

0.36

106.33

1.4

—

Finngen Rheumatological endpoints

1379

14048

0.55

100.25

1.5

1.4

—

Tramadol

548

8254

0.40

99.65

1.5

1.4

—

Postpartum hemorraghe, parous women as controls

2592

14571

1.64

98.40

1.6

1.4

—

Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium

2355

13103

1.62

95.36

1.5

1.4

—

ILD medications: prednisolone, methylprednisolone, prednisone

1548

14820

0.57

94.68

1.5

1.4

—

Exclusions for E4_PCOS_CONSORTIUM

1230

13928

0.54

94.56

1.4

—

Any event in cancer register

995

11319

0.51

93.53

1.4

—

Benzodiazepine use

1239

15320

0.55

92.26

1.4

—

Oral corticosteroids

1309

13744

0.56

91.14

1.5

1.4

—

Abnormalities of forces of labour

420

1466

3.05

90.46

1.6

1.4

—

Caries of enamel

2751

13148

1.54

89.29

1.5

1.4

—

Diseases of oesophagus, stomach and duodenum

1114

12251

0.54

88.73

1.5

1.4

—

Pregnancy hypertension

2237

12948

1.61

87.61

1.5

1.4

—

Diabetes, insulin treatment (Kela reimbursement)

504

7314

0.41

86.65

1.4

—

Other obstetric trauma

410

1478

3.16

86.47

1.4

—

Diabetes, insuline treatment (Kela reimbursement), excluding more controls

504

7204

0.42

84.05

1.4

—

Placenta praevia

345

1150

3.43

83.53

1.5

1.3

—

Labour and delivery complicated by umbilical cord complications

288

852

3.77

83.43

2.0

1.4

—

Medical treatment for female infertility

1666

10284

1.73

81.80

1.4

1.5

—

Codeine or tramadol medication

1725

15156

0.61

81.08

1.4

—

Nerve, nerve root and plexus disorders

1130

12217

0.56

78.02

1.5

1.4

—

Persons encountering health services for other counselling and medical advice, not elsewhere classified

2972

11039

1.48

78.01

1.4

—

Fall on same level

1806

15532

0.63

77.88

1.4

—

Cardiovascular diseases (excluding rheumatic etc)

1534

14317

0.60

77.53

1.5

1.4

—

Sleep apnoea

316

5707

0.35

77.03

1.4

—

Pain in throat and chest

1054

11342

0.55

77.01

1.5

1.4

—

Other puerperal infections

889

4822

2.13

74.98

1.5

—

Other assisted single delivery

107

9.80

74.48

1.4

1.1

—

Inflammatory bowel disease treatment related agents

1747

15344

0.63

74.42

1.5

1.4

—

Influenza and pneumonia

1474

15244

0.61

74.33

1.5

1.4

—

Tonsillectomy and adenotomy

2791

13485

1.48

73.14

1.5

1.4

—

Codeine

1698

14500

0.63

72.86

1.4

—

Pre-eclampsia or poor fetal growth

1922

12576

1.60

72.41

1.5

1.4

—

Other bacterial diseases

915

10582

0.54

70.96

1.5

1.4

—

Other heart diseases, wide

1117

11751

0.57

70.30

1.4

—

Other diseases of intestines

1762

15489

0.64

70.07

1.5

1.4

—

Chronic apical periodontitis

1739

15333

0.64

69.65

1.5

1.4

—

Metabolic disorders

515

6857

0.45

69.09

1.4

—

Liveborn infants according to place of birth

17.84

68.57

1.4

—

ILD medications

1849

15290

0.65

68.52

1.5

1.4

—

Hypertensive diseases

350

4932

0.40

65.92

1.5

1.4

—

Other obstructed labour

317

1134

2.99

65.68

1.4

—

Hypertension

350

4909

0.40

65.22

1.5

1.4

—

All pneumoniae

1264

13781

0.60

64.77

1.5

1.4

—

Malignant neoplasm, wide definition for exclusion

559

6733

0.48

63.10

1.4

—

Pneumonias (Asthma/COPD co-morbidities)

1254

13662

0.61

62.86

1.5

1.4

—

Other intervertebral disc disorders

811

8891

0.54

62.62

1.5

1.4

—

Hypertensive diseases (excluding secondary)

350

4927

0.41

61.98

1.5

1.4

—

Diabetes mellitus

1350

12528

0.62

60.68

1.4

—

Abnormalities of breathing

1565

13951

0.64

60.44

1.4

—

Diabetes, varying definitions

1315

12262

0.62

59.59

1.4

—

Condition for Implicit Sepsis (Organ dysfunction codes)

890

10687

0.57

59.19

1.5

1.4

—

Gestational [pregnancy-induced] hypertension

1580

10375

1.59

59.05

1.5

1.4

—

Pneumonia (excl. viral and due to other infectious organisms not elsewhere classified)

1161

12835

0.61

58.00

1.5

1.4

—

Twin gestation

426

1876

2.42

57.60

1.5

1.3

—

Multiple gestation

434

1937

2.38

56.82

1.5

1.3

—

Artrosis, including avohilmo

492

5584

0.48

56.77

1.4

—

Malignant neoplasm

450

5676

0.46

56.59

1.4

—

Autoimmune diseases excluding thyroid diseases, strict definition

1633

13419

0.66

55.92

1.5

1.4

—

Contact with and exposure to communicable diseases

818

13956

0.56

55.44

1.3

1.4

—

Hypertension, essential

307

4259

0.40

55.37

1.5

1.4

—

Intracranial trauma

957

11245

0.59

55.05

1.5

1.4

—

COPD/asthma/ILD related pneumonia or pneumonia derived septicaemia

1265

12044

0.63

54.90

1.5

1.4

—

1265

12044

0.63

54.90

1.5

1.4

—

Autoimmune diseases excluding thyroid diseases

1669

13556

0.66

54.82

1.5

1.4

—

Dentofacial anomalies [including malocclusion]

2495

14387

1.42

54.69

1.5

1.4

—

All kidney diseases

1435

14938

0.65

54.20

1.4

—

Symptoms and signs involving cognition, perception, emotional state and behaviour

1088

12007

0.61

54.02

1.5

1.4

—

Female infertility, associated with anovulation

929

5618

1.85

53.80

1.5

1.4

—

First line medication for Crohn's disease

1945

15145

0.69

53.65

1.5

1.4

—

Poor fetal growth

1165

7431

1.71

53.13

1.5

1.4

—

Solid cancers, helper endpoint

445

5465

0.48

52.17

1.4

—

Diabetes medication

1360

12358

0.65

52.00

1.4

—

Pain in limb

1338

13642

0.65

50.85

1.5

1.4

—

Antihypertensive medication - note that there are other indications

1987

14881

0.69

50.30

1.4

—

Other antidepressants

1616

12207

0.67

50.19

1.4

—

Pneumonia, organism unspecified

961

11005

0.61

49.75

1.5

1.4

—

Excessive vomiting in pregnancy

503

2552

2.13

48.33

1.5

1.4

—

Polyarthropathies

719

8170

0.57

47.62

1.5

1.4

—

Persons with potential health hazards related to communicable diseases

944

14937

0.61

47.40

1.4

—

Type 2 diabetes

1100

10078

0.63

46.77

1.4

—

Other bacterial diseases

678

8022

0.56

46.68

1.4

—

Condition for Implicit Sepsis (Organ dysfunction codes)

714

8730

0.57

46.64

1.5

1.4

—

Kela-code for severe mental illness

294

6654

0.43

45.68

1.5

1.4

—

Exposure to unspecified factor

1513

15825

0.68

45.21

1.4

—

Persons with potential health hazards related to family and personal history and certain conditions influencing health status

1419

13553

0.67

44.11

1.5

1.4

—

Leiomyoma of uterus

388

4481

0.48

43.05

1.4

—

Shoulder lesions

360

4524

0.48

42.05

1.4

—

Schizophrenia or delusion, excluding more controls

265

5933

0.43

41.26

1.4

—

Disorders of gallbladder, biliary tract and pancreas

900

9027

0.62

41.09

1.5

1.4

—

Arthrosis

274

3395

0.44

40.18

1.4

—

Periodontitis

797

8653

0.61

39.98

1.5

1.4

—

Disorders of adult personality and behaviour

545

9569

0.55

39.94

1.4

—

Complications of surgical and medical care, not elsewhere classified

1275

12806

0.67

39.75

1.5

1.4

—

Cardiac arrhythmias

903

9223

0.63

39.73

1.5

1.4

—

Infections of breast associated with childbirth

345

1672

2.37

39.62

1.5

1.4

—

Implicit Sepsis

671

8264

0.59

39.57

1.5

1.4

—

Injuries to the head

1833

15505

0.72

39.10

1.4

—

Chronic periodontitis, including avohilmo

795

8605

0.61

39.02

1.5

1.4

—

Constipation

608

7225

0.58

38.32

1.4

—

Personality disorders, excluding more controls

527

9215

0.55

38.19

1.4

—

Other nutritional deficiencies

2103

14740

1.36

37.71

1.5

1.4

—

Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

1181

11974

0.67

37.30

1.5

1.4

—

Complications of the puerperium, not elsewhere classified

346

1714

2.27

37.02

1.4

—

Unspecified mental disorder

476

8494

0.55

36.20

1.4

—

Atopic dermatitis

2279

14135

1.34

36.14

1.4

—

Opioids

2136

14775

0.74

36.09

1.4

—

Chronic diseases of tonsils and adenoids

2447

11740

1.33

36.06

1.4

—

Menorrhagia

644

5928

0.59

35.95

1.5

1.4

—

Schizophrenia or delusion

265

5626

0.46

34.81

1.4

—

Schizophrenia, schizotypal and delusional disorders

265

5624

0.46

34.77

1.4

—

Substance abuse, excluding more controls

615

8665

0.60

34.26

1.4

—

Other heart diseases

543

6073

0.58

34.23

1.4

—

Lower back pain or/and sciatica

1740

15383

0.73

33.70

1.5

1.4

—

Renal tubulo-interstitial diseases

1194

12729

0.69

33.04

1.4

—

Type 2 diabetes, definitions combined, including avohilmo

992

8603

0.67

32.95

1.4

—

Inflammatory disorders of breast

490

2825

1.89

32.65

1.6

1.4

—

Personality disorders

527

8814

0.58

32.17

1.4

—

Asthma/COPD (KELA code 203)

1608

14981

0.73

32.13

1.4

—

Persons encountering health services in other circumstances, wide

2754

11039

1.29

32.08

1.5

1.4

—

Spondylopathies

402

4399

0.54

31.73

1.4

—

Other disorders of ear

691

7190

0.62

31.60

1.5

1.4

—

Type 2 diabetes, wide definition

186

2788

0.42

30.42

1.4

—

Heart failure, not strict

1767

0.27

30.22

1.3

1.4

—

Other and unspecified nonorganic psychotic disorders

203

4448

0.44

29.57

1.4

—

Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified

759

7441

0.65

29.19

1.5

1.4

—

Other (not insulin) diabetes medications

1010

8646

0.69

28.45

1.4

—

Polycystic ovarian syndrome, broad definition

1086

7791

1.50

28.25

1.5

—

Other specific joint derangements/joint disorders

1650

14141

0.74

28.12

1.5

1.4

—

Type 2 diabetes, definitions combined

975

8291

0.68

28.04

1.4

—

Type 2 diabetes, strict (exclude DM1)

974

8283

0.69

28.00

1.4

—

Specific personality disorders

485

7959

0.59

27.61

1.4

—

Venous complications and haemorrhoids in pregnancy

148

581

2.94

27.28

1.7

1.4

—

Low back pain

1396

13525

0.73

26.99

1.5

1.4

—

Concussion

906

10682

0.68

26.96

1.5

1.4

—

Disorders of tooth development and eruption

716

3772

1.58

26.88

1.4

—

Cholelithiasis, broad definition with cholecystitis

803

8029

0.67

26.84

1.5

1.4

—

Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified (FINNGEN)

490

5102

0.60

26.59

1.5

1.4

—

Disorders of lipoprotein metabolism and other lipidaemias

149

2237

0.41

26.57

1.4

—

Endometriosis

965

8057

0.69

26.43

1.4

—

Migraine, single triptan purchase ok & required. ICD-code if available is included

2488

13384

1.27

26.40

1.4

—

Triptan medication for migraine, single purchase ok

2488

13384

1.27

26.40

1.4

—

Injuries to the knee and lower leg

2151

15187

0.78

25.82

1.4

—

Disorders of eyelid, lacrimal system and orbit

903

9818

0.69

25.08

1.4

—

Intrahepatic Cholestasis of Pregnancy (ICP)

474

2906

1.75

25.00

1.5

1.4

—

Implicit Sepsis

545

6505

0.63

24.95

1.5

1.4

—

Anaemias

705

6847

0.65

24.94

1.5

1.4

—

Pre-eclampsia or eclampsia

887

6181

1.48

24.74

1.5

1.4

—

Other soft tissue disorders, not elsewhere classified

1882

14155

0.77

24.58

1.5

1.4

—

Intrahepatic Cholestasis of Pregnancy (ICP) , incl. ICD-8

474

2906

1.72

24.54

1.5

1.4

—

Hard cardiovascular diseases

151

2099

0.43

24.41

1.5

1.4

—

Pre-eclampsia

870

6065

1.48

24.31

1.5

1.4

—

ILD medications: immunosuppressive drugs

793

10691

0.68

24.28

1.5

1.4

—

Dyspnoea

1049

10740

0.72

23.97

1.4

—

Postpartum haemorrhage due to anatomy

1409

10928

1.41

23.87

1.6

1.4

—

Bleeding

423

4996

0.60

23.62

1.5

1.4

—

Ischemic heart diseases

1619

0.36

23.45

1.6

1.4

—

Habitual aborter

219

1108

2.29

23.01

1.7

1.4

—

Lumbar disc prolapse

600

6996

0.65

22.93

1.5

1.4

—

Diarrhoea and gastroenteritis of presumed infectious origin

2524

13444

1.25

22.72

1.5

1.4

—

All anxiety disorders

2201

13916

1.26

22.64

1.4

—

Cholelithiasis

786

7818

0.69

22.62

1.5

1.4

—

Disorders of choroid and retina

341

4197

0.57

22.47

1.4

—

Bipolar affective disorders

349

5895

0.58

22.38

1.4

—

Hernia

836

7958

0.70

21.91

1.5

1.4

—

553

7418

0.65

21.61

1.4

1.5

—

Schizophrenia

1754

0.26

21.56

1.3

1.4

—

Behavioural and emotional disorders with onset usually occurring in childhood and adolescence

896

10922

0.71

21.17

1.4

—

Other disorders of breast and lactation associated with childbirth

214

1128

2.29

20.93

1.3

1.4

—

Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified

115

442

2.70

20.83

1.4

—

Acute upper respiratory infections

2560

12880

1.23

20.67

1.5

1.4

—

Examination and observation for other reasons

1605

7185

1.30

20.48

1.6

1.4

—

Hyperkinetic disorders, excluding more controls

447

6597

0.62

20.46

1.4

—

Asthma, unspecified (mode), excluding more controls

674

7320

0.68

20.43

1.5

1.4

—

Any reimbursement code in KELA

2025

12632

0.79

20.41

1.4

—

Malaise and fatigue

478

5974

0.64

20.39

1.4

—

Obesity

1878

14482

1.26

20.00

1.6

1.4

—

Insomnia

2458

14672

1.23

19.92

1.4

—

Mental and behavioural disorders due to psychoactive substance use

636

8579

0.68

19.87

1.4

—

Obesity and other hyperalimentation

1879

14488

1.26

19.79

1.6

1.4

—

Asthma, unspecified (mode)

674

7319

0.69

19.71

1.5

1.4

—

Biguanides

983

8151

0.73

19.65

1.4

—

Gonarthrosis

124

1631

0.43

19.64

1.4

—

Ectopic pregnancy

541

3576

1.55

19.57

1.5

1.4

—

Injuries to the shoulder and upper arm

775

8774

0.71

19.50

1.5

1.4

—

Emotionally unstable personality disorder

345

5583

0.59

19.30

1.4

1.5

—

Endometriosis diagnosis and infertility diagnosis occurring together

526

3491

1.57

19.29

1.4

—

Gender identity disorders

631

0.09

19.23

1.2

1.4

—

Placental disorders

252

3.53

19.22

1.6

1.2

—

Conductive and sensorineural hearing loss

299

3462

0.58

19.03

1.5

1.4

—

Oxicams

204

2214

0.52

19.00

1.5

1.4

—

Gonarthrosis [arthrosis of knee](FG)

124

1640

0.44

18.92

1.4

—

Sleep disorders

2394

14222

1.23

18.73

1.4

—

Polycystic ovarian syndrome, consortium definition

2087

15151

0.81

18.64

1.4

—

520

7006

0.67

18.40

1.4

1.5

—

Chronic lower respiratory diseases

2322

15009

0.82

18.10

1.4

—

Medical abortion

2396

10721

1.23

17.73

1.5

1.4

—

Anxiety (asthma-related co-morbidities)

2087

13203

1.24

17.61

1.4

—

Behavioural syndromes associated with physiological disturbances and physical factors

2422

14228

1.22

17.50

1.4

—

Erysipelas

322

4015

0.61

17.06

1.4

—

Neurotic, stress-related and somatoform disorders

2397

13916

1.21

17.02

1.5

1.4

—

Care involving use of rehabilitation procedures

550

7347

0.68

16.99

1.3

1.4

—

Alcohol use disorder, Swedish definition

403

5693

0.64

16.80

1.4

1.5

—

Pre-existing hypertension complicating pregnancy, childbirth and the puerperium

347

2163

1.67

16.77

1.6

1.4

—

Substance abuse

615

8200

0.70

16.76

1.4

—

Depression medications

1183

7678

0.76

16.66

1.4

—

Anxiety disorders

2397

13912

1.21

16.37

1.5

1.4

—

Selective serotonin reuptake inhibitors

1909

12207

0.81

16.33

1.4

—

Other disorders of urethra and urinary system

1209

11179

0.77

16.16

1.4

—

Symptoms and signs involving the urinary system

560

6136

0.69

16.13

1.5

1.4

—

Artificial joint operation, meniscal resection

318

3344

0.61

16.05

1.4

—

Major coronary heart disease event

1223

0.40

15.56

1.6

1.4

—

L02BG Aromatase inhibitors

252

1452

1.75

15.48

1.5

1.4

—

Disturbance of activity and attention

430

6165

0.66

15.21

1.4

—

Dermatitis and eczema

2696

14137

1.19

15.17

1.5

1.4

—

Unspecified maternal hypertension

107

483

2.58

15.08

1.7

1.4

—

Polyp of the female genital tract

410

3548

0.66

15.02

1.4

—

Wide developmental disorders, excluding more controls

1105

0.24

14.91

1.3

1.4

—

Sensorineural hearing loss

212

2526

0.57

14.84

1.5

1.4

—

Pure hypercholesterolaemia

122

1649

0.48

14.63

1.4

—

Noninflammatory disorders of female genital tract

2263

9506

1.21

14.61

1.5

1.4

—

Malignant neoplasm of breast

133

1741

0.50

14.60

1.4

—

Hypothyroidism, drug reimbursement

273

3125

0.60

14.60

1.4

—

Sleep disorders (combined)

2233

13977

0.83

14.49

1.4

—

Persistent mood disorders

199

3479

0.56

14.47

1.4

—

Dizziness and giddiness

820

8629

0.75

14.44

1.5

1.4

—

Any mental disorder

1970

11905

0.82

14.43

1.5

1.4

—

Hyperkinetic disorders

447

6297

0.67

14.43

1.4

—

Emergency coronary revascularization (for ACS)

1138

0.40

14.36

1.6

1.4

—

Malignant neoplasm of breast, including Hilmo

153

1890

0.52

14.34

1.4

—

Malignant neoplasm of breast, HER2-negative, including Hilmo

153

1890

0.52

14.34

1.4

—

Coronary revascularization (ANGIO or CABG)

1137

0.41

14.11

1.6

1.4

—

Percutaneous Coronary Intervention

1135

0.41

14.01

1.6

1.4

—

Psychiatric diseases

1757

10695

0.82

13.89

1.4

—

Dorsalgia

2180

13894

0.83

13.88

1.5

1.4

—

Mental and behavioural disorders due to alcohol

463

6412

0.69

13.88

1.4

1.5

—

Malignant neoplasm of breast, HER2-negative

124

1636

0.49

13.85

1.4

—

Any death

837

0.27

13.76

1.4

—

Other neurological diseases

424

4889

0.68

13.74

1.5

1.4

—

Rotator cuff syndrome

185

2361

0.56

13.72

1.4

—

Suicide or other Intentional self-harm

365

5452

0.66

13.57

1.4

—

Second line medication for Crohn's disease

655

8861

0.73

13.50

1.5

1.4

—

Obesity due to excess calories

1391

11269

1.25

13.47

1.5

1.4

—

Cardiovascular diseases

2297

14555

0.84

13.46

1.5

1.4

—

Hypothyroidism, strict autoimmune, 3 medication purchases required

1775

14440

0.82

13.43

1.5

1.4

—

Migraine

2079

14202

1.20

13.24

1.5

1.4

—

Ischaemic heart disease, wide definition

808

0.32

13.24

1.5

1.4

—

Symptoms and signs involving the nervous and musculoskeletal systems

616

8377

0.73

13.15

1.4

—

Other retinal disorders

262

3281

0.62

13.14

1.4

—

Ovarian cyst

1223

8786

0.79

13.12

1.5

1.4

—

Acute upper respiratory infections of multiple and unspecified sites

2068

12879

1.20

13.10

1.5

1.4

—

Phobic anxiety disorders

376

5496

0.66

13.09

1.5

1.4

—

Benign neoplasms

2277

14795

0.84

13.08

1.4

—

Diseases of middle ear and mastoid

2161

14952

1.19

13.08

1.4

—

Other arrhythmias

714

7185

0.74

13.03

1.4

—

Covid-19 suspected case

809

6174

1.33

13.02

1.5

1.4

—

Autism spe, excluding more controls

917

0.22

12.98

1.3

1.4

—

Meniscus derangement

222

2496

0.60

12.90

1.5

1.4

—

Autoimmune diseases related-to ILD

1389

14574

0.81

12.89

1.5

1.4

—

Disorders of lens

1042

0.41

12.84

1.5

1.4

—

L04AX Other immunosuppressants

605

8212

0.73

12.78

1.5

1.4

—

Tobacco use

167

918

1.89

12.66

1.5

1.4

—

Headache

1946

13052

1.20

12.60

1.5

1.4

—

Wide developmental disorders

1014

0.27

12.52

1.3

1.4

—

Postpartum haemorrhage due to retained placenta

1113

8998

1.29

12.50

1.6

1.4

—

Iron deficiency

216

1313

1.80

12.44

1.5

1.4

—

Heart failure and antihypertensive medication

359

0.16

12.34

1.8

1.4

—

Fever of other and unknown origin

796

9212

0.76

12.30

1.5

1.4

—

Gonarthrosis,primary

1123

0.44

12.28

1.5

1.4

—

STROKE

153

1881

0.55

12.07

1.4

—

Other symptoms and signs involving the nervous and musculoskeletal systems

483

6716

0.71

11.97

1.4

—

Other degenerative diseases of the nervous system

152

2043

0.55

11.97

1.4

—

Maternal care for cervical incompetence

180

1040

1.83

11.89

1.5

1.4

—

Asthma (diagnoses ohter than nonallergic)

1534

15329

0.82

11.87

1.4

—

Alcohol dependence

1467

0.41

11.62

1.4

—

Autism

873

0.25

11.57

1.3

1.4

—

Disorders of psychological development

309

4237

0.66

11.35

1.4

—

Mental and behavioural disorders due to alcohol, excluding acute intoxication

305

4544

0.66

11.31

1.5

1.4

—

Cerebrovascular diseases

145

1829

0.56

11.19

1.4

—

Gastro-oesophageal reflux disease

569

6604

0.74

11.18

1.5

1.4

—

Autism spe

839

0.25

11.18

1.3

1.4

—

Complications of procedures, not elsewhere classified

1118

11428

0.80

11.13

1.5

1.4

—

Poisoning by drugs, medicaments and biological substances

462

6369

0.71

11.13

1.4

—

Premature separation of placenta [abruptio placentae]

373

2.35

11.10

1.6

1.3

—

Oxycodone

1355

0.43

11.08

1.4

—

Open wound of wrist and hand

643

8266

0.75

11.03

1.5

1.4

—

Mixed and other personality disorders

1769

0.47

10.98

1.3

1.4

—

Complications associated with artificial fertilization

161

942

1.90

10.90

1.5

1.4

—

Ovarian hyperstimulation (induction)

154

892

1.93

10.86

1.5

1.4

—

Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances

316

4619

0.67

10.79

1.4

—

Social phobias

226

3502

0.62

10.64

1.4

—

Injuries to the elbow and forearm

1129

12158

0.81

10.50

1.4

—

Disorders of skin appendages

948

11789

0.80

10.50

1.4

—

Depression or dysthymia

1053

7206

0.80

10.43

1.5

1.4

—

Cystitis

2499

12901

1.16

10.33

1.4

—

Other arthrosis

101

1357

0.51

10.17

1.4

—

Dental pulpitis, including avohilmo

2584

14629

1.15

10.14

1.5

1.4

—

Obstructed labour due to maternal pelvic abnormality

123

656

1.89

10.03

1.5

1.4

—

Coronary atherosclerosis

506

0.26

9.83

1.8

1.4

—

Alcohol use disorder, ICD-based

291

4270

0.68

9.82

1.5

1.4

—

Maternal care for known or suspected disproportion

105

539

2.01

9.82

1.5

1.3

—

Family history of certain disabilities and chronic diseases leading to disablement

254

1683

1.58

9.77

1.9

1.4

—

All chronic kidney diseases

362

4183

0.70

9.75

1.4

—

Any mental disorder, or suicide (or attempt), or psychic disorders complicating pregnancy, partum or puerperium or nerve system disorders

1231

10224

1.22

9.71

1.4

—

Acute tubulo-interstitial nephritis

987

10475

0.81

9.61

1.4

—

Poisoning by medicine

433

5881

0.73

9.58

1.4

1.5

—

Disorders of thyroid, IBD co-morbidities

530

4925

0.74

9.55

1.5

1.4

—

Schizoaffective disorder

1348

0.44

9.51

1.3

1.4

—

Spondylosis

101

1557

0.53

9.51

1.3

1.4

—

Diseases of arteries, arterioles and capillaries

171

2074

0.61

9.51

1.4

—

Other specified and unspecified personality disorders

120

2124

0.55

9.51

1.4

—

Cerebrovascular diseases (FINNGEN)

121

1534

0.55

9.43

1.4

—

KRA_PSY_EATING, excluding more controls

477

6246

0.73

9.39

1.5

1.4

—

Other sexually transmitted chlamydial diseases

471

3535

1.39

9.32

1.6

1.4

—

Coxibs

569

3936

0.75

9.27

1.4

—

Nonorganic sleeping disorders, excluding more controls

427

5758

0.73

9.08

1.3

1.4

—

L04AA Selective immunosuppressants

163

2640

0.61

8.90

1.4

—

Injuries to the hip and thigh

277

3638

0.69

8.76

1.5

1.4

—

Acute and transient psychotic disorders

1497

0.49

8.69

1.5

1.4

—

Syncope and collapse

482

5466

0.75

8.68

1.5

1.4

—

Acetic acid derivatives and related substances

578

3898

0.76

8.67

1.4

—

Infections, IBD-co-morbidities

157

1816

0.61

8.44

1.5

1.4

—

Intracranial injury

853

9924

0.81

8.43

1.4

—

Non-selective monoamine reuptake inhibitors

142

2261

0.60

8.35

1.4

—

Inflammatory disease of uterus

665

5287

1.29

8.20

1.6

1.4

—

Carpal tunnel syndrome

472

5476

0.76

8.13

1.5

1.4

—

Other disorders of skin and subcutaneous tissue

586

6663

0.78

8.13

1.4

—

Dissociative [conversion] disorders

1511

0.51

8.09

1.4

—

Oter anti-inflammatory and antirheumatic agents, non-steroids

597

0.42

7.99

1.5

1.4

—

Fenamates

298

2839

0.70

7.96

1.4

—

Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis

2000

13858

1.15

7.95

1.5

1.4

—

Other eating disorders

224

3230

0.66

7.93

1.5

1.4

—

Female infertility, tubal origin

176

1126

1.61

7.83

1.4

—

Other and unspecified mood [affective] disorders

193

2886

0.65

7.81

1.5

1.4

—

Covid-19 confirmed case

407

5411

0.75

7.72

1.4

—

Diabetic nephropathy, excluding more controls

863

0.43

7.66

1.4

—

Sodium-glucose co-transporter 2 (SGLT2) inhibitors

1347

0.50

7.64

1.4

—

Glucagon-like peptide-1 (GLP-1) analogues

1347

0.50

7.64

1.4

—

Complications specific to multiple gestation

3.51

7.63

1.5

1.3

—

Renal failure

1122

0.49

7.61

1.4

—

Inguinal hernia

325

2998

0.72

7.55

1.5

1.4

—

Sciatica+with lumbago

593

6894

0.79

7.51

1.4

—

Bacterial infection, other or unspecified

354

4056

0.73

7.49

1.4

—

Drug-induced neutropenia

394

0.23

7.43

1.9

1.5

—

Endocrine, nutritional and metabolic diseases

2672

12060

1.13

7.38

1.5

1.4

—

Bacterial Sepsis

169

2228

0.65

7.36

1.5

1.4

—

Insulin medication

550

5884

0.78

7.29

1.4

—

Substance use, excluding alcohol

248

3525

0.70

7.29

1.4

—

Emotional disorders starting during childhood or adolecense, excluding more controls

194

2760

0.65

7.27

1.4

—

Diarrhoea and gastroenteritis of presumed infectious origin

1361

14259

0.85

7.26

1.5

1.4

—

Agoraphobia

1238

0.49

7.23

1.5

1.4

—

Fitting and adjustment of other devices

1155

0.51

7.14

1.4

—

Heart failure,strict

435

0.29

7.14

1.6

1.4

—

Other external causes of accidental injury

1938

11049

0.87

7.07

1.5

1.4

—

Heart failure, strict

432

0.29

7.05

1.6

1.4

—

Disorders of synovium and tendon

806

8570

0.82

7.04

1.5

1.4

—

Mental and behavioural disorders due to multiple drug use and use of multiple drugs and use of other psychoactive substances

1503

0.55

7.04

1.2

1.4

—

Accidents

1939

11049

0.87

7.02

1.5

1.4

—

Stroke, including SAH

1089

0.54

7.01

1.4

—

Vaginitis/vulvovaginitis/vulvitis/abscess of vulva

848

7047

1.23

7.00

1.5

1.4

—

Falls/tendency to fall

2532

14185

0.89

6.95

1.4

—

External causes of morbidity and mortality

1737

9956

0.87

6.88

1.5

1.4

—

Convulsions, not elsewhere classified

359

4708

0.75

6.88

1.5

1.4

—

Acne

405

5230

0.75

6.82

1.4

—

All-cause Heart Failure

418

0.30

6.65

1.6

1.4

—

Epilepsy

317

4257

0.74

6.64

1.5

1.4

—

Other cataract

773

0.47

6.60

1.5

1.4

—

Medicines for HER+ breast cancer

302

2087

1.38

6.57

1.5

1.4

—

Organic, including symptomatic, mental disorders

705

0.46

6.52

1.5

1.4

—

Post-traumatic stress disorder

341

4475

0.74

6.49

1.5

1.4

—

Panic disorder

512

6412

0.78

6.48

1.4

—

Bacterial infection, other or unspecified

276

3289

0.73

6.46

1.5

1.4

—

Care involving dialysis

359

0.25

6.42

1.3

1.5

—

Dislocation, sprain and strain of joints and ligaments of knee

1149

12346

0.85

6.42

1.4

—

Injuries to the wrist and hand

1971

15367

0.88

6.33

1.4

—

Senile cataract

382

0.34

6.31

1.4

1.5

—

Systemic connective tissue disorders

292

3947

0.74

6.28

1.4

—

Nephropathy related operations

521

0.29

6.28

1.3

1.4

—

Use of disulfiram, acamprosate or naltrexone

504

0.28

6.27

1.2

1.4

—

Exposure to other specified factors

1383

14570

0.87

6.21

1.5

1.4

—

Dialysis, with operation codes

518

0.29

6.21

1.3

1.4

—

Eating disorders

482

6013

0.78

6.21

1.5

1.4

—

Other general symptoms and signs

970

0.48

6.18

1.3

1.4

—

Ischaemic Stroke, excluding all haemorrhages

791

0.50

6.15

1.4

—

Bronchitis

2573

14600

1.11

6.10

1.5

1.4

—

Other diseases of blood and blood-forming organs, wide

103

1690

0.61

6.08

1.5

1.4

—

Diverticular disease of intestine

109

1138

0.61

6.08

1.4

—

Chronic kidney disease

702

0.40

5.98

1.5

1.4

—

Other and unspecified dermatitis

671

8136

0.82

5.93

1.5

1.4

—

Abnormal findings on diagnostic imaging and in function studies, without diagnosis

311

3699

0.75

5.90

1.5

1.4

—

Eating disorder

477

5902

0.78

5.89

1.5

1.4

—

Acne vulgaris

312

4085

0.74

5.87

1.4

—

Nonorganic sleeping disorders

427

5405

0.78

5.82

1.3

1.4

—

Inflammatory diseases of female pelvic organs

2251

14888

1.12

5.80

1.5

1.4

—

Other menopausal disorders

144

1234

0.65

5.79

1.4

—

Erysipelas

191

2419

0.70

5.78

1.3

1.4

—

Mouth breathing

198

2805

0.70

5.76

1.4

—

Stroke, excluding SAH

930

0.56

5.76

1.4

—

Puerperal sepsis

219

1559

1.42

5.72

1.5

1.4

—

Implicit bacterial Sepsis

128

1706

0.65

5.71

1.5

1.4

—

Childhood allergy (age < 16)

993

9481

0.84

5.70

1.4

—

Intentional self-harm by sharp object

872

0.47

5.70

1.3

1.4

—

Implicit bacterial Sepsis

1397

0.61

5.64

1.5

1.4

—

Dislocation, sprain and strain of joints and ligaments at wrist and hand level

517

6383

0.80

5.58

1.5

1.4

—

Mental retardation, excluding more controls

567

0.37

5.54

1.4

—

Supplementary factors related to causes of morbidity and mortality classified elsewhere

413

5227

0.78

5.53

1.4

1.5

—

Other systemic involvement of connective tissue (FG)

231

3125

0.72

5.52

1.4

—

Venous complications and haemorrhoids in the puerperium

214

2.24

5.51

1.8

1.5

—

Transplanted organ and tissue status

571

0.36

5.48

1.3

1.4

—

Focal epilepsy

180

2565

0.70

5.48

1.6

1.4

—

Ulcer of lower limb, not elsewhere classified

313

0.25

5.46

1.3

1.4

—

Other joint disorders

2431

14145

0.90

5.33

1.5

1.4

—

Infections with a predominantly sexual mode of transmission

1835

15325

1.13

5.32

1.5

1.4

—

Other and unspecified coagulation defects

145

974

1.53

5.30

1.6

1.5

—

Osteopathies and chondropathies

491

5657

0.81

5.29

1.4

—

Insulin, fast-acting (human)

210

2891

0.72

5.28

1.4

—

Genitourinary diseases

1360

5959

1.15

5.25

1.4

—

Other diseases of pleura

1091

0.58

5.21

1.4

—

Emotional disorders and disorders of social functioning with onset specific to childhood

214

2839

0.72

5.14

1.4

—

Gestational [pregnancy-induced] oedema and proteinuria without hypertension

227

1663

1.39

5.13

1.5

1.4

—

Sub-endpoint used in defining T1D endpoints

361

4523

0.78

5.12

1.4

1.5

—

Hypertrophy of breast

232

3130

0.73

5.11

1.5

1.4

—

Abnormal findings on examination of blood, without diagnosis

243

3001

0.74

5.10

1.4

—

Symptoms and signs involving the digestive system and abdomen

2269

10263

1.11

5.09

1.5

1.4

—

Abdominal and pelvic pain

2263

10263

1.11

5.07

1.5

1.4

—

Insulin, fast-acting or short human

366

4643

0.78

5.03

1.4

1.5

—

Insulin, intermediate and long-acting

403

4918

0.79

5.02

1.4

—

Atrial fibrillation and flutter

652

0.54

5.00

1.4

—

Other systemic involvement of connective tissue

235

3160

0.74

5.00

1.4

—

Other diseases of urinary system

2524

12902

1.10

5.00

1.4

—

Hypertrophy of breast in women and men

233

3130

0.74

4.98

1.5

1.4

—

Focal epilepsy, strict definition

145

2108

0.68

4.97

1.6

1.4

—

Dermatitis

815

9507

0.85

4.91

1.5

1.4

—

Any mental disorder, or suicide (or attempt), or psychic disorders complicating pregnancy, partum or puerperum or nerve system disorders, excluding more controls

1231

10800

1.15

4.88

1.4

—

Persons encountering health services for specific procedures, not carried out

101

1563

0.64

4.83

1.2

1.4

—

Insulin, fast-acting

366

4613

0.79

4.79

1.4

—

Obsessive-compulsive disorder

233

3082

0.74

4.78

1.5

1.4

—

Valvular heart disease excluding rheumatic fever

133

1417

0.68

4.76

1.4

—

Malignant neoplasm of breast, ER-positive, including Hilmo

946

0.59

4.75

1.4

—

Cholecystectomy

668

6844

0.84

4.73

1.5

1.4

—

Focal epilepsy, mode (most common among epilepsy diagnosis)

149

2132

0.69

4.71

1.6

1.4

—

Mental retardation, wide definition

536

0.40

4.68

1.4

—

Schizotypal disorder

373

0.29

4.64

1.4

—

Mood disorders, excluding more controls

1795

11904

0.90

4.63

1.4

—

Use of biperiden

302

0.30

4.62

1.4

—

Hallux valgus (acquired)

153

1571

0.70

4.61

1.5

1.4

—

Mental retardation

531

0.40

4.60

1.4

—

Malignant neoplasm of breast, HER-positive

888

0.59

4.58

1.4

—

Generalized anxiety disorder

616

7288

0.83

4.54

1.4

—

Peripheral artery disease

360

0.35

4.53

1.6

1.5

—

Other and unspecified tonsillitis

1234

11702

0.88

4.52

1.5

1.4

—

Other symptoms and signs involving cognitive functions and awareness

191

2377

0.73

4.51

1.7

1.4

—

Liquid cancers, helper endpoint

102

1362

0.65

4.49

1.4

—

Type 1 diabetes

360

4498

0.79

4.47

1.4

—

Non-rheumatic valve diseases

131

1380

0.68

4.47

1.4

—

Diseases of arteries, arterioles and capillaries (FINNGEN)

486

0.48

4.43

1.7

1.4

—

Pervasive developmental disorders excl. Autism + Asperger

253

0.26

4.43

1.1

1.4

—

Extracorporeal dialysis

260

0.27

4.42

1.4

1.5

—

Complications of anaesthesia during labour and delivery

116

2.63

4.41

1.7

1.4

—

Other disorders of fluid, electrolyte and acid-base balance

1174

0.61

4.38

1.5

1.4

—

Unspecified haematuria

125

1515

0.68

4.36

1.5

1.4

—

Speech and linguistic disorders, excluding more controls

248

3026

0.76

4.35

1.4

—

Angina pectoris

296

0.36

4.33

1.3

1.5

—

Diabetic retinopathy, excluding more controls

134

1088

0.69

4.32

1.4

—

Fibromyalgia

120

1750

0.68

4.32

1.5

1.4

—

Female genital prolapse

261

1923

0.76

4.29

1.5

1.4

—

Congenital malformations of uterus and cervix

141

1000

1.49

4.28

1.5

1.4

—

Type of accident

378

4680

0.80

4.27

1.4

—

Sleep disorders, other/unspecified

897

0.55

4.27

1.5

—

Glaucoma

109

1401

0.67

4.26

1.5

1.4

—

Emotional disorders starting during childhood or adolescence

195

2559

0.73

4.19

1.4

—

Type 1 diabetes, wide definition

335

4184

0.79

4.18

1.4

—

Problems related to lifestyle

293

2298

1.29

4.18

1.6

1.4

—

Diabetic nephropathy

827

0.55

4.17

1.4

—

Reimbursement for rheumatic diseases

641

7506

0.85

4.15

1.5

1.4

—

Coxarthrosis

617

0.57

4.13

1.5

1.4

—

Asthma, hospital admissions , main diagnosis only

1570

15350

0.90

4.12

1.4

—

Unspecified abortion

398

1.71

4.11

1.4

—

Autoimmune diseases

2475

13698

0.92

4.09

1.5

1.4

—

Polycystic ovarian syndrome

471

3948

1.24

4.06

1.4

—

Use of pramipexole

895

0.57

4.05

1.5

1.4

—

Pneumonitis due to solids and liquids

232

0.26

4.02

1.3

1.4

—

Fracture of lower leg, including ankle

575

6732

0.84

4.01

1.4

1.5

—

Kidney transplant status

345

0.32

3.98

1.5

1.4

—

Episodal and paroxysmal disorders

2573

14205

0.92

3.97

1.5

1.4

—

Pregnant state, incidental

14.82

3.96

1.7

1.2

—

Presence of other functional implants

998

0.66

3.94

1.4

—

L04AC Interleukin inhibitors

805

0.55

3.93

1.5

1.4

—

Dipeptidyl peptidase 4 (DPP-4) inhibitors

661

0.56

3.91

1.3

1.4

—

Other acute lower respiratory infections

748

8235

0.86

3.89

1.5

1.4

—

Hydatidiform mole

326

1.80

3.87

1.7

1.3

—

Neurological diseases

2387

13033

0.92

3.87

1.5

1.4

—

Bitten or struck by other mammals

223

2884

0.76

3.81

1.4

—

Type 1 diabetes, wide definition, subgroup 1

332

4101

0.80

3.79

1.4

—

Injury, poisoning and certain other consequences of external causes

1536

8530

0.90

3.79

1.5

1.4

—

Excessive, frequent and irregular menstruation

1552

9390

0.90

3.76

1.5

1.4

—

Open wound of forearm

1429

0.67

3.72

1.4

—

Insulin, combination of fast acting with intermediate-acting or long-acting

550

5929

0.84

3.72

1.4

—

Mental and behavioural disorders due to sedatives or hypnotics

929

0.60

3.70

1.2

1.4

—

Other abnormal uterine and vaginal bleeding

367

3216

0.81

3.70

1.4

—

Atherosclerosis, excluding cerebral and coronary sclerosis

173

0.27

3.68

2.5

1.4

—

Unknown and unspecified causes of morbidity

928

0.60

3.67

1.4

—

Other septicaemia

179

2293

0.75

3.66

1.5

1.4

—

Other coagulation defects

175

1305

1.36

3.65

1.5

1.4

—

Embedded and impacted teeth

1698

12798

1.11

3.65

1.4

—

Other disorders of white blood cells

457

0.43

3.63

1.6

1.4

—

Unspecified fall

587

6765

0.85

3.62

1.4

—

Other medical care

320

3562

0.81

3.62

1.3

1.4

—

L04AD Calcineurin inhibitors

986

0.61

3.60

1.5

1.4

—

Fracture of forearm

767

8054

0.87

3.60

1.4

—

Coxarthrosis [arthrosis of hip](FG)

630

0.59

3.59

1.5

1.4

—

Other reaction to severe stress, and adjustment disorders

1048

11755

0.89

3.59

1.5

1.4

—

Other problems related to primary support group, including family circumstances

470

3849

1.21

3.56

1.7

1.4

—

Other disorders of bladder

564

0.49

3.56

1.1

1.4

—

Complications of medical and surgical care

936

9731

0.88

3.55

1.5

1.4

—

Hypermobility syndrome

134

1834

0.71

3.54

1.4

—

Non-ischemic cardiomyopathy

345

0.42

3.54

1.6

1.5

—

Biological medication for rheuma

283

3526

0.80

3.52

1.5

1.4

—

Other disorders of eye and adnexa

188

2463

0.76

3.52

1.4

—

Agranulocytosis

830

0.59

3.50

1.4

—

Anankastic personality disorder

1005

0.62

3.48

1.4

—

COPD

619

0.57

3.46

1.8

1.5

—

Other follicular disorders

107

1521

0.69

3.46

1.5

1.4

—

Cough

490

5477

0.84

3.44

1.4

—

Other chronic obstructive pulmonary disease, including avohilmo

790

0.62

3.44

1.6

1.4

—

Fungal Sepsis

261

0.34

3.43

1.7

1.5

—

Abnormal findings in secretions and smears from cervix uteri vagina vulva

1982

13785

1.09

3.42

1.4

—

Continuous positive airway pressure

492

0.51

3.41

1.4

—

Other diseases of upper respiratory tract

2436

11740

1.08

3.41

1.5

1.4

—

malignant neoplasm of female genital organs

604

0.52

3.40

1.5

1.4

—

Mental and behavioural disorders due to use of other stimulants, including caffeine

661

0.55

3.35

1.2

1.4

—

Rheumatoid arthritis

234

2664

0.78

3.35

1.5

1.4

—

240

3024

0.79

3.34

1.3

1.4

—

Diseases of liver

158

2108

0.75

3.32

1.4

—

Septicaemia

218

2606

0.78

3.30

1.5

1.4

—

Major coronary heart disease event excluding revascularizations

306

0.46

3.30

1.5

1.4

—

Infections of the skin and subcutaneous tissue

971

10784

0.89

3.28

1.4

—

Other dorsopathies, not elsewhere classified

2466

13901

0.93

3.28

1.5

1.4

—

Superficial injury of lower leg

425

5049

0.84

3.27

1.4

1.5

—

Mental and behavioural disorders due to opioids

917

0.62

3.26

1.3

1.4

—

Radiculopathy

813

0.60

3.23

1.3

1.4

—

Endocrine disorders, other/unspecified

250

0.35

3.23

1.3

1.5

—

Acute suppurative otitis media

1013

10537

0.89

3.22

1.5

1.4

—

Infections with a predominantly sexual mode of transmission

1290

11690

1.11

3.20

1.5

1.4

—

Excessive earwax

400

4660

0.84

3.19

1.4

—

Other enthesopathies

226

2858

0.79

3.18

1.4

—

Diabetic neuropathy

334

0.39

3.18

1.2

1.5

—

Hyperlipidaemia, other/unspecified

497

0.52

3.13

1.5

1.4

—

Spinal stenosis

431

0.53

3.12

1.4

—

Respiratory diseases principally affecting the interstitium, IBD co-morbidites

287

0.44

3.11

1.2

1.4

—

Dementia, including avohilmo

260

0.42

3.10

1.8

1.5

—

Anxiety disorders, excluding more controls

1983

11904

1.09

3.10

1.5

1.4

—

Dislocation, sprain and strain of joints and ligaments at ankle and foot level

1071

11823

0.90

3.06

1.4

—

Implicit fungal Sepsis

247

0.36

3.05

1.7

1.5

—

Hidradenitis suppurativa

985

0.64

3.05

1.5

1.4

—

Cervicalgia

180

2325

0.77

3.04

1.5

1.4

—

Rheumatism, unspecified

956

0.65

3.01

1.5

1.4

—

Diabetic maculopathy

1080

0.67

3.01

1.4

—

Other and unspecified effects of external causes

621

7109

0.87

3.01

1.5

1.4

—

Anxious personality disorder

585

0.55

3.00

1.5

1.4

—

Diseases of vocal cords and larynx+other diseases of upper respiratory tract, no elsewhere classified

595

6647

0.87

3.00

1.5

1.4

—

Secondary malignant neoplasm of other and unspecified sites, including Hilmo

392

0.45

3.00

1.3

1.4

—

Deep bite

161

1843

0.76

2.99

1.3

1.4

—

Nystagmus and other irregular eye movements

226

0.34

2.99

1.5

—

Superficial injury of ankle and foot

262

3220

0.80

2.98

1.4

—

Other/unspecified dorsalgia

545

6240

0.86

2.95

1.5

1.4

—

Carrier of infectious disease

562

1.50

2.93

1.5

1.4

—

Non-invasive ventilation

471

3591

1.18

2.93

1.4

—

Other ill-defined and unspecified causes of mortality

0.00

2.93

0.0

1.3

—

Intestinal infectious diseases

2486

13236

1.08

2.93

1.5

1.4

—

Adverse effects, not elsewhere classified

413

4860

0.84

2.92

1.5

1.4

—

Chronic ulcer of skin, not elsewhere classified

239

0.37

2.92

1.4

—

Fall on and from stairs and steps

254

3131

0.81

2.90

1.4

—

Use of teriflunomide

219

0.35

2.89

1.1

1.4

—

Combinations of oral blood glucose lowering drugs

377

0.45

2.88

1.5

1.4

—

Hypothyroidism, strict autoimmune

1815

12916

0.92

2.88

1.5

1.4

—

Diffuse brain injury

401

0.47

2.87

1.4

—

Pain and other conditions associated with female genital organs and menstrual cycle

874

8955

0.89

2.87

1.4

—

Other and unspecified disorders of white blood cells

318

0.40

2.87

1.4

—

Certain conditions originating in the perinatal period

285

3060

0.81

2.85

1.4

—

Acute alcohol intoxication

222

2771

0.80

2.84

1.4

—

Other chronic obstructive pulmonary disease

567

0.60

2.83

1.8

1.4

—

severe traumatic brain injury, does not include concussion

845

0.64

2.82

1.5

1.4

—

Exclusions for E4_PCOS_BROAD

215

2684

0.79

2.82

1.5

1.4

—

Symptoms and signs involving the circulatory and respiratory systems

2606

13951

0.93

2.81

1.5

1.4

—

Tumor necrosis factor alpha inhibitors

269

3273

0.82

2.77

1.4

—

Open wound of head

450

5054

0.86

2.75

1.4

—

Dermatographic urticaria

113

1524

0.73

2.74

1.5

1.4

—

Hypo-osmolality and hyponatraemia

433

0.50

2.73

1.3

1.4

—

338

0.46

2.72

1.4

—

Other disorders of adrenal gland

561

0.56

2.72

1.5

1.4

—

Soft tissue disorders

2578

14165

0.93

2.71

1.5

1.4

—

Diseases of appendix

1359

13359

0.91

2.71

1.4

—

Abnormalities of heart beat

541

6084

0.87

2.70

1.5

1.4

—

Other noninflammatory disorders of uterus, except cervix

776

0.69

2.70

1.5

1.4

—

Adrenocortical insufficiency

350

0.45

2.69

1.4

—

Diabetic retinopathy

140

1151

0.76

2.69

1.4

—

Acute bronchitis

501

5664

0.86

2.69

1.5

1.4

—

Toxic effect of other and unspecified substances

304

0.41

2.69

1.2

1.4

—

Disorder of lipoprotein metabolism, unspecified

167

0.30

2.68

1.2

1.5

—

Asthma, excluding more controls

1644

9296

0.92

2.68

1.4

—

Monoamine oxidase A inhibitors

820

0.64

2.67

1.5

1.4

—

Paroxysmal tachycardia

267

2716

0.82

2.66

1.5

1.4

—

Fentanyl

232

0.39

2.65

1.3

1.5

—

Diabetic maculopathy, excluding more controls

1115

0.69

2.64

1.4

—

Presence of cardiac and vascular implants and grafts

427

0.57

2.63

1.5

1.4

—

Psoriasis

211

2622

0.80

2.62

1.6

1.4

—

Fracture of femur

631

0.62

2.61

1.6

1.4

—

Ehlers-Danlos syndrome

430

0.51

2.60

1.3

1.4

—

Appendicitis, broad definition

1354

13331

0.92

2.60

1.4

—

Diseases of salivary glands

412

4805

0.85

2.60

1.4

1.5

—

Injury of muscle and tendon at hip and thigh level

680

0.61

2.60

1.4

—

Other functional intestinal disorders

507

5404

0.87

2.58

1.5

1.4

—

Nonalcoholic fatty liver disease

703

0.62

2.57

1.5

1.4

—

Ehlers-Danlos syndrome

336

0.45

2.57

1.3

1.4

—

Myocardial infarction

245

0.46

2.57

1.6

1.4

—

Personal history of certain other diseases

129

989

1.36

2.56

1.6

1.4

—

Umbilical hernia

316

2645

1.20

2.56

1.6

1.4

—

Conduction disorders

1100

0.73

2.55

1.4

—

Retention of urine

120

1310

0.75

2.53

1.5

1.4

—

Brachial plexus disorders

132

1721

0.76

2.52

1.5

1.4

—

Dementia

228

0.45

2.51

1.8

1.5

—

Neurological diseases, wide definition

1303

7133

0.91

2.50

1.5

1.4

—

Strabismus

465

5339

0.86

2.50

1.4

—

Unicornuate uterus

190

2.00

2.50

1.4

—

Heart failure and bmi 25plus

153

0.40

2.50

1.8

1.5

—

Conjunctivitis

1967

15319

1.08

2.50

1.4

—

Used for control exclusion in common control thyroid runs

2462

13254

0.94

2.49

1.5

1.4

—

Psychotic depression

104

1397

0.73

2.49

1.5

1.4

—

Adalimumab

133

1728

0.76

2.48

1.4

—

Pustular psoriasis

325

0.46

2.47

1.2

1.4

—

COPD, early/later onset

558

0.62

2.47

1.8

1.4

—

Other specified congenital malformation syndromes affecting multiple systems

321

0.45

2.47

2.0

1.4

—

Mental and behavioural disorders of puerperium, not classified elsewhere

455

1.53

2.46

1.5

1.4

—

Irregular menses

1759

14914

0.93

2.46

1.4

—

Cervicobrachial syndrome

211

2599

0.81

2.45

1.4

—

Asthma

1644

9307

0.92

2.45

1.4

—

COPD, hospital admissions

558

0.62

2.44

1.8

1.4

—

Sequelae of injuries of head

455

0.54

2.44

1.6

1.4

—

Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances

116

1529

0.75

2.44

1.4

—

Any dementia, excluding more controls

177

0.39

2.44

1.6

1.5

—

Transient ischemic attack

883

0.70

2.43

1.4

—

Neuromuscular dysfunction of bladder

631

0.61

2.43

1.6

1.4

—

Demyelinating diseases of the central nervous system

150

1911

0.78

2.43

1.4

—

COPD (mode)

400

0.57

2.42

2.0

1.5

—

Mixed specific developmental disorders

508

0.58

2.42

1.2

1.4

—

Peripheral artery operations in Hilmo

159

0.31

2.40

1.2

1.4

—

Endometriosis ASRM stages 1,2

456

5230

0.86

2.40

1.4

—

Lesion of ulnar nerve

1001

0.70

2.40

1.5

1.4

—

Use of antiglaucoma preparations and miotics

175

0.34

2.40

1.3

1.5

—

Mild mental retardation

372

0.50

2.39

1.4

—

Cerebral palsy and other paralytic syndromes

1174

0.72

2.39

1.4

—

Acute alcohol intoxication, ICD10

222

2710

0.81

2.39

1.4

—

Striae atrophicae

274

0.42

2.38

1.3

1.5

—

Use of fingolimod

312

0.46

2.37

1.2

1.5

—

Sequelae of cerebrovascular disease

543

0.62

2.37

1.5

1.4

—

Methotrexate

111

1470

0.75

2.36

1.5

1.4

—

Persistent delusional disorders

425

0.54

2.36

1.6

1.4

—

Neuralgia and neuritis, unspecified

513

0.58

2.36

1.2

1.4

—

Varicose veins

186

1751

0.80

2.35

1.5

1.4

—

Chronic periodontitis, complicated

222

2685

0.82

2.35

1.4

—

Chronic hepatitis, not elsewhere classified

290

0.44

2.34

1.9

1.4

—

Congenital malformations of the nervous system

593

0.61

2.34

1.4

—

Other diseases of liver

1261

0.73

2.32

1.4

—

Implicit fungal Sepsis

573

0.61

2.32

1.6

1.4

—

MS-disease / Multiple Sclerosis

135

1728

0.77

2.30

1.4

—

Arthropathies

2634

14145

0.94

2.30

1.5

1.4

—

Hirsutism in women

882

0.68

2.29

1.3

1.4

—

Biomechanical lesions, not elsewhere classified

373

1.52

2.29

1.3

1.4

—

Manic episode

568

0.61

2.29

1.3

1.4

—

Dialysis

185

0.38

2.28

1.6

1.5

—

Mental and behavioural disorders associated with the puerperium

463

1.50

2.28

1.5

1.4

—

Postviral fatigue syndrome

280

0.44

2.27

1.2

1.5

—

Coxarthrosis, primary

379

0.56

2.27

1.4

—

Malignant neoplasm of bone and articular cartilage

0.00

2.27

0.0

1.3

—

Leisure time condition

224

2713

0.82

2.25

1.4

—

Ulcerative colitis, NAS

174

2162

0.80

2.25

1.6

1.4

—

Secondary parkinsonism, excluding more controls

0.00

2.25

0.0

1.5

—

Periapical abscess

443

5078

0.87

2.24

1.4

—

Missing teeth due to accident, extraction or parodontitis

280

3135

0.84

2.24

1.4

—

Aplastic and other anaemias

201

2297

0.81

2.24

1.4

—

Primary_lymphoid and hematopoietic malignant neoplasms

929

0.70

2.23

1.5

1.4

—

Other skin changes

179

1439

1.25

2.21

1.5

1.4

—

Other and unspecified injuries of lower leg

111

1450

0.76

2.21

1.4

—

COPD related to multimorbidity

264

0.48

2.21

1.5

—

Other strabismus

441

5022

0.87

2.21

1.4

—

Ovarian dysfunction

524

4658

1.15

2.19

1.4

1.5

—

Hypertrichosis

944

0.70

2.18

1.3

1.4

—

Other disorders of binocular vision

432

1.49

2.18

1.4

—

Glomerular disorders in diseases classified elsewhere

817

0.68

2.18

1.4

—

Disorders of ocular muscles, binocular movement, accommodation and refraction

1064

11485

0.91

2.17

1.4

—

Intestinal infectious diseases

2132

15204

1.07

2.16

1.5

1.4

—

Vasculitis limited to skin, not elsewhere classified

149

0.33

2.16

1.0

1.4

—

Polyuria

103

1359

0.76

2.15

1.5

1.4

—

Habit and impulse disorders

304

0.48

2.14

1.8

1.4

—

Ulcerative ileocolitis

583

0.63

2.13

1.5

1.4

—

Ulcerative colitis

349

4048

0.86

2.13

1.5

1.4

—

Disorders of parathyroid gland

567

0.63

2.13

1.3

1.4

—

Elevated blood glucose level

741

0.67

2.13

1.4

—

Anorexia (incl.atypical)

255

3010

0.83

2.12

1.5

1.4

—

Disorders of sclera, cornea, iris and ciliary body

735

8137

0.90

2.11

1.4

—

Alcohol abuse, main dg, excluding more controls

188

2298

0.81

2.10

1.4

—

Primary gonarthrosis, bilateral

308

0.53

2.10

1.3

1.5

—

Causalgia

209

0.42

2.10

1.2

1.4

—

Other benign neoplasms of skin

354

3049

1.16

2.10

1.4

—

Haemorrhoids and perianal venous thrombosis

294

2489

1.18

2.10

1.5

1.4

—

Vitreous haemorrhage

546

0.62

2.09

1.2

1.5

—

Bacterial pneumoniae

348

3559

0.86

2.09

1.5

1.4

—

Exclusion endpoint for clefts

403

0.56

2.08

2.1

1.4

—

Diseases of the skin and subcutaneous tissue

2245

11954

0.94

2.08

1.5

1.4

—

Noninfective enteritis and colitis

714

7897

0.90

2.08

1.5

1.4

—

Malignant neoplasm of retroperitoneum and peritoneum, including Hilmo

0.00

2.07

0.0

1.4

—

Benign neoplasm: Skin of ear and external auricular canal

222

1.64

2.07

1.5

—

Open wound of ankle and foot

123

1572

0.78

2.07

1.4

—

Invasive ventilation

455

0.59

2.04

1.4

—

Oligomenorrhoea

170

1385

1.26

2.04

1.4

—

Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium

694

1.37

2.04

1.5

1.4

—

Abscess of anal and rectal regions

862

0.70

2.02

1.4

—

Urticaria and erythema

759

8359

0.90

2.02

1.4

—

Abnormal results of function studies

954

0.72

2.02

1.6

1.4

—

Medial epicondylitis

259

0.46

2.01

1.3

1.4

—

Postprocedural musculoskeletal disorders, not elsewhere classified

162

0.37

2.01

1.7

1.4

—

Decubitus ulcer and pressure area

146

0.34

2.01

1.2

1.5

—

Secondary malignant neoplasm of respiratory and digestive organs, including Hilmo

313

0.51

2.00

1.5

—

Vocal cord dysfunction

168

1854

0.81

2.00

1.4

—

Inflammatory bowel disease

496

5589

0.88

1.99

1.5

1.4

—

Asthma, including avohilmo

2495

14797

0.94

1.99

1.4

—

Gout

204

0.43

1.98

1.6

1.5

—

Speech and linguistic disorders

248

2808

0.84

1.98

1.4

—

Congenital malformations and deformations of the musculoskeletal system

200

2392

0.82

1.98

1.4

—

COPD, hospital admissions 1, only main diagnosis

430

0.62

1.97

1.9

1.4

—

Other diseases of the respiratory system

574

0.64

1.96

1.4

—

Other respiratory disorders and diseases

574

0.64

1.96

1.4

—

Congenital malformations of the musculoskeletal system, not elsewhere classified

419

0.58

1.96

1.5

1.4

—

Bulimia nervosa (incl. atypical)

193

2306

0.81

1.96

1.5

1.4

—

Fracture at wrist and hand level

470

5295

0.88

1.95

1.4

—

Myocardial infarction, strict

203

0.49

1.94

1.6

1.4

—

Benign neoplasm of ovary

107

1381

0.77

1.94

1.4

—

Polymorphous light eruption

141

0.34

1.94

1.2

1.4

—

Plantar fascial fibromatosis

785

0.70

1.94

1.3

1.4

—

Other diseases of intestine

424

0.59

1.93

1.4

—

0.00

1.93

0.0

1.4

—

Coagulation defects, purpura and other haemorrhagic conditions

320

2759

1.17

1.93

1.5

1.4

—

Asthma (only as main-diagnosis), excluding more controls

1518

9296

0.93

1.93

1.4

—

COPD, hospital admissions 3, with asthma pneumonia sepsis

219

0.47

1.93

1.8

1.5

—

Papulosquamous disorders

289

3373

0.85

1.93

1.5

1.4

—

Seborrhoeic dermatitis

772

0.70

1.92

1.4

—

Car occupant injured in noncollision transport accident

101

776

1.32

1.92

1.4

—

Adhesive capsulitis of shoulder

606

0.66

1.91

1.4

—

Other and unspecified disorders of adult personality and behaviour

185

0.41

1.91

1.5

—

Any dementia

159

0.44

1.91

1.6

1.4

—

Pacemaker

417

0.60

1.91

1.2

1.5

—

Viral and other specified intestinal infections

1001

10462

0.92

1.90

1.4

—

Melanocytic naevi

679

6146

1.11

1.90

1.4

—

Use of dimethyl fumarate

274

0.49

1.90

1.2

1.5

—

Neovascular glaucoma

226

0.44

1.90

1.4

1.5

—

Congenital malformations of the musculoskeletal system, not elsewhere classified

537

0.63

1.90

1.4

—

Diseases of the musculoskeletal system and connective tissue

1927

10267

0.94

1.90

1.5

1.4

—

Lung diseases due to external agents

409

0.59

1.90

1.5

1.4

—

Autoimmune hyperthyroidism

133

1058

1.27

1.90

1.4

—

Coxarthrosis, primary, with hip surgery

163

0.40

1.90

1.1

1.4

—

Malignant neoplasm of bone and articular cartilage of other and unspecified sites, including Hilmo

0.00

1.90

0.0

1.3

—

Dorsopathies

2597

13907

0.95

1.89

1.5

1.4

—

Necrosis of pulp, including avohilmo

1072

11561

0.92

1.89

1.5

1.4

—

Secondary parkinsonism

0.00

1.89

0.0

1.4

—

Transient global amnesia

0.00

1.88

0.0

1.4

—

Other condition

163

1994

0.81

1.88

1.4

—

Special screening examination for other diseases and disorders

211

1761

1.21

1.88

1.5

1.4

—

Venous thromboembolism

269

3043

0.85

1.87

1.5

—

Other shoulder lesions

100

1293

0.77

1.87

1.3

1.4

—

Lateral epicondylitis

896

0.72

1.87

1.5

1.4

—

Hypothyreosis and Thyroxine purchase for inclusion criteria

2119

14702

0.94

1.86

1.5

1.4

—

Urticaria

668

7366

0.90

1.86

1.4

—

Torsion of ovary, ovarian pedicle and fallopian tube

677

1.35

1.86

1.3

1.4

—

Neoplasms

2522

14076

0.95

1.86

1.4

—

Secondary hypertension

546

0.65

1.86

1.4

—

Asthma, hospital admission 2, infections

987

10478

0.92

1.85

1.5

1.4

—

Asthma-related infections

987

10478

0.92

1.85

1.5

1.4

—

Ocular pain

123

1546

0.79

1.85

1.4

—

Pustulosis palmaris et plantaris

290

0.51

1.85

1.2

1.4

—

Other and unspecified psoriasis

417

0.60

1.84

1.9

1.4

—

Unspecified kidney failure

198

0.45

1.83

1.4

1.5

—

Paranoid personality disorder

325

0.54

1.83

1.7

1.4

—

Glaucoma secondary to other eye disorders

222

0.45

1.83

1.4

1.5

—

Congenital absence of the uterus

0.00

1.82

0.0

1.3

—

Other diseases of spinal cord

221

0.45

1.81

1.8

1.4

—

Poisoning by narcotics and psychodysleptics [hallucinogens]

386

0.58

1.81

1.3

1.4

—

Pain in joint

1345

7990

1.08

1.81

1.5

1.4

—

Eosinophilia

167

0.41

1.81

2.0

1.4

—

Blood alcohol or alcohol intoxication level

485

0.63

1.81

1.3

1.4

—

Seropositive rheumatoid arthritis, strict definition

1141

0.76

1.81

1.4

—

Mental and behavioural disorders due to cannabinoids

664

0.68

1.80

1.4

—

Etanercept

1046

0.75

1.79

1.5

1.4

—

Migraine without aura

792

8633

0.91

1.79

1.4

—

Other spirochaetal diseases

303

2618

1.16

1.79

1.5

1.4

—

Thyrotoxicosis with diffuse goitre

291

2511

1.17

1.78

1.4

—

Congenital malformations of genital organs

386

3386

1.15

1.78

1.5

1.4

—

Malignant neoplasm of cervix uteri, including Hilmo

447

0.62

1.78

1.7

1.4

—

Sicca syndrome [Sjögren]

630

0.68

1.78

1.5

1.4

—

Thyrotoxicosis, other and/or unspecified

377

3314

1.14

1.77

1.5

1.4

—

Other anxiety disorders

1703

13900

1.07

1.77

1.4

—

Astigmatism

1187

0.77

1.76

1.5

1.4

—

Unspecified privation

1270

0.77

1.76

1.4

—

Mental and behabioural disorders of puerperum, not classified elsewhere, excluding more controls

488

1.41

1.76

1.5

—

Ascites

152

0.39

1.76

1.2

1.4

—

Other blood glucose lowering drugs, excl. Insulins

153

0.39

1.75

1.3

1.4

—

Algoneurodystrophy

542

0.65

1.75

1.3

1.4

—

COPD, hospital admission 2, with asthma infections

375

0.62

1.75

1.6

1.4

—

IBD patients in KELA-register

406

4584

0.88

1.75

1.5

1.4

—

Thyrotoxicosis

417

3693

1.13

1.74

1.5

1.4

—

Melanocytic naevi, other sites/unspecified

150

1223

1.24

1.74

1.6

1.4

—

Systemic lupus erythematosus, unspecified

420

0.61

1.73

1.4

1.5

—

Superficial injury of wrist and hand

465

5201

0.89

1.73

1.4

—

Any prescribed medicine buy

2.13

1.71

1.6

1.2

—

Bacterial pneumonia (organism specified)

363

3743

0.88

1.71

1.5

1.4

—

Other and unspecified injuries of ankle and foot

1023

0.75

1.70

1.5

1.4

—

Anomalies of dental arch relationship, including avohilmo

514

5148

0.89

1.70

1.4

—

Unspecified behavioural syndromes associated with physiological disturbances and physical factors +Physiological and behavioural factors associated with disorders of diseases classified elsewhere

354

0.58

1.70

1.8

1.4

—

Congenital malformations and deformations of the musculoskeletal system

248

2868

0.85

1.69

1.4

—

Budesonide

201

2382

0.84

1.69

1.5

1.4

—

Disorder of the sleep-wake schedule

403

0.61

1.69

1.4

—

Malignant neoplasm of cervix uteri

278

0.53

1.69

1.7

1.5

—

Malignant neoplasm of endocrine gland

634

0.69

1.68

1.4

—

Secondary parkinsonism+Parkinsonism in other disease

0.00

1.68

0.0

1.4

—

Extrapyramidal and movement disorders

194

2309

0.84

1.68

1.3

1.4

—

Family history of other conditions

421

1.42

1.68

1.6

1.4

—

In situ neoplasms

497

5533

0.90

1.67

1.4

—

Congenital malformations, deformations and chromosomal abnormalities

1786

15546

1.06

1.67

1.5

1.4

—

Other CVD (FINNGEN)

438

0.67

1.67

1.8

1.4

—

Personal history of risk-factors, not elsewhere classified

351

0.58

1.66

1.1

1.4

—

Haemorrhage from respiratory passages

169

1835

0.83

1.66

1.4

—

Disorders of conjunctiva

2014

15319

1.06

1.66

1.4

—

Inflammatory bowel disease, strict (require KELA)

406

4566

0.89

1.66

1.5

1.4

—

Fibroblastic disorders

911

0.74

1.65

1.3

1.4

—

Sequelae of injuries of neck and trunk

265

0.52

1.65

1.5

1.4

—

Gonarthrosis, primary, with knee surgery

120

0.40

1.65

1.0

1.4

—

Status epilepticus

291

0.55

1.65

1.4

1.5

—

ILD medications: azathioprine

212

2495

0.85

1.65

1.6

1.4

—

Atrial septal defect, secundum type

437

0.63

1.65

1.5

1.4

—

Lyme disease

294

2553

1.15

1.65

1.5

1.4

—

Cellulitis

215

2529

0.85

1.65

1.4

—

Glaucoma suspect

1148

0.77

1.64

1.5

1.4

—

Other headache syndromes

861

9318

0.92

1.64

1.5

1.4

—

Injury of muscle and tendon at neck level

2.49

1.64

1.2

1.3

—

Open wound of shoulder and upper arm

289

0.54

1.64

1.6

1.4

—

Open wound of lower leg

158

1908

0.82

1.64

1.3

1.4

—

Abnormal findings on diagnostic imaging of lung

1089

0.77

1.63

1.5

1.4

—

Asthma (mode)

1649

9373

0.94

1.63

1.4

—

Arthropathies in other diseases classified elsewhere

264

0.53

1.63

1.4

1.5

—

Dental caries

290

3203

0.87

1.63

1.5

1.4

—

Transport accidents

1178

10848

0.93

1.63

1.4

—

SLE, ICD10

449

0.64

1.62

1.4

—

SLE, strict definition

449

0.64

1.62

1.4

—

Gout, FINNGEN

211

0.47

1.62

1.6

1.5

—

Drugs, medicaments and biological substances causing adverse effects in therapeutic use

1220

0.78

1.62

1.6

1.4

—

Rare circulating lymphoid malignancy, including Hilmo

223

0.49

1.61

1.6

1.4

—

Enterobiasis

114

920

1.28

1.60

1.5

1.4

—

Previous suicide attempt

309

0.56

1.60

1.2

1.4

—

Other disorders of bone

272

3132

0.86

1.60

1.4

—

Migraine without aura and triptan purchases

642

7017

0.91

1.59

1.4

1.5

—

Other inflammation of vagina/vulva

163

1362

1.22

1.59

1.4

—

Endometriosis of pelvic peritoneum

450

4775

0.89

1.59

1.4

—

Cerebral cysts

1136

0.78

1.58

1.5

1.4

—

Collagenous colitis

845

0.74

1.58

1.7

1.4

—

Unspecified acute lower respiratory infection

119

1473

0.80

1.58

1.4

—

Primary ovarian failure

596

0.69

1.58

1.4

—

Azathioprine

212

2484

0.85

1.58

1.6

1.4

—

Glomerular diseases

113

1407

0.80

1.58

1.4

—

Hepatic failure, not elsewhere classified

174

0.46

1.58

1.5

1.4

—

Other disorders of nervous system

209

0.48

1.58

1.4

1.5

—

Congenital deformities of feet

563

0.68

1.58

1.5

1.4

—

Graves disease, strict definition

241

2075

1.17

1.58

1.4

—

Early syphilis

157

0.44

1.57

1.7

1.4

—

Pyogenic granuloma

290

1.48

1.57

1.5

1.4

—

Exposure to controlled fire, not in building or structure

0.00

1.56

0.0

1.3

—

Candidiasis

758

6977

1.09

1.56

1.5

1.4

—

Effects of other deprivation

0.00

1.56

0.0

1.3

—

Other spirochaetal diseases

309

2706

1.14

1.56

1.5

1.4

—

Fracture of foot, except ankle

440

4903

0.89

1.55

1.4

1.5

—

Extreme obesity with alveolar hypoventilation

156

0.45

1.55

2.4

1.5

—

Systemic lupus erythematosus

468

0.65

1.55

1.4

—

Uterine polyps

763

1.28

1.55

1.7

1.4

—

Other ulcerative colitis

863

0.75

1.55

1.4

—

Colectomy operation

577

0.69

1.55

1.6

1.4

—

Acute renal failure

506

0.67

1.54

1.4

—

Bronchiectasis

157

0.44

1.54

1.3

1.5

—

Other and unspecified anaemias

178

2016

0.84

1.54

1.4

—

Osteosarcoma, including Hilmo

0.00

1.54

0.0

1.4

—

Acute lymphocytic leukaemia, helper endpoint

167

0.46

1.54

1.9

1.4

—

Acute lymphocytic leukaemia

167

0.46

1.54

1.9

1.4

—

Acute lymphocytic leukaemia, including Hilmo

167

0.46

1.54

1.9

1.4

—

Trochanteric bursitis

853

0.75

1.53

1.4

—

Candidiasis

261

2265

1.16

1.53

1.6

1.4

—

Acute appendicitis

1302

12951

0.94

1.53

1.4

—

Somatoform disorder

276

3160

0.87

1.53

1.5

1.4

—

Atrial fibrillation and flutter with reimbursement

109

0.47

1.52

1.4

1.5

—

Seronegative juvenile rheumatoid arthritis

750

0.73

1.52

1.4

1.5

—

Symptoms and signs involving appearance and behaviour

166

0.47

1.51

1.8

1.5

—

Irritable bowel syndrome

533

5871

0.90

1.51

1.4

—

Corns and callosities

418

0.64

1.50

1.5

1.4

—

Implicit viral Sepsis

248

2860

0.86

1.50

1.5

1.4

—

Other anaemias

181

2036

0.84

1.50

1.4

—

Diseases of the myoneural junction and muscle

608

0.70

1.50

1.5

1.4

—

Myeloproliferative diseases (CML excluded)

244

0.53

1.50

1.4

1.5

—

Certain infectious and parasitic diseases

1606

8522

0.94

1.50

1.5

1.4

—

Spirochaetal infections, other/unspecified

299

2621

1.14

1.50

1.5

1.4

—

Other and unspecified vasculitis limited to skin

128

0.39

1.50

1.0

1.4

—

Hyperprolactinaemia

956

0.76

1.50

1.4

—

Injury of other and unspecified intrathoracic organs

332

0.60

1.50

1.6

1.4

—

Diseases of the digestive system

394

4389

0.89

1.49

1.5

1.4

—

Other and unspecified polyneuropathies, also in other diseases

502

0.68

1.49

1.4

—

Bacterial pneumonia, not elsewhere classified

326

3252

0.88

1.49

1.5

1.4

—

Other and unspecified injuries of abdomen, lower back and pelvis

319

1.45

1.49

1.5

1.4

—

Other malignant neoplasms of skin (=non-melanoma skin cancer), including Hilmo

509

0.73

1.49

1.5

1.4

—

Impacted teeth

1277

10697

1.07

1.49

1.4

—

Evidence of alcohol involvement determined by level of intoxication

265

0.55

1.49

1.1

1.4

—

Other fall from one level to another

373

4178

0.89

1.47

1.5

1.4

—

SLE (Finngen)

462

0.66

1.47

1.4

—

Asthma (only as main-diagnosis)

1518

9307

0.94

1.46

1.4

—

Diseases of pulp and periapical tissues, including avohilmo

2442

13239

0.95

1.46

1.5

1.4

—

Other mental disorders due to brain damage and dysfunction and to physical disease

280

0.57

1.46

1.3

1.4

—

Malignant neoplasm of thyroid gland

580

0.70

1.46

1.4

—

Tooth eruption problems

766

8057

0.92

1.46

1.4

—

Diseases of thymus

3.24

1.45

1.6

1.1

—

Residual foreign body in soft tissue

660

0.72

1.45

1.2

1.4

—

Eosinophilic disease (BM)

151

0.46

1.45

2.0

1.4

—

Noninfectious colitis NAS

154

1838

0.83

1.45

1.6

1.4

—

Benign neoplasm: Skin of eyelid, including canthus

708

1.27

1.45

1.4

—

Hyperparathyroidism

398

0.64

1.45

1.4

—

Other and unspecified disorders of psychological development

270

0.57

1.44

1.3

1.4

—

Otitis media, unspecified

320

3322

0.88

1.44

1.4

—

Cerebral palsy

362

0.62

1.44

1.6

1.4

—

Seborrhoeic keratosis

489

1.33

1.44

1.6

1.5

—

Other acute skin changes due to ultraviolet radiation

201

0.49

1.44

1.4

1.5

—

Assault

236

2717

0.86

1.44

1.4

—

Injury of muscle and tendon at shoulder and upper arm level

810

0.75

1.44

1.5

1.4

—

Pericarditis

151

0.46

1.43

1.3

1.4

—

L02BA Anti-estrogens

752

0.74

1.43

1.4

—

Unspecific neurodegenerative disorder

0.42

1.43

1.8

1.4

—

Golimumab

564

0.70

1.43

1.3

1.4

—

Diseases of the eye and adnexa

2387

12512

0.95

1.42

1.4

—

Struck by thrown, projected or falling objec

657

0.72

1.42

1.5

1.4

—

Deep endometriosis

201

2336

0.85

1.42

1.3

1.4

—

Hernia of abdominal wall

414

3718

1.12

1.41

1.6

1.4

—

Disorders of optic nerve and visual pathways

142

1700

0.83

1.41

1.5

1.4

—

Cardiac arrest

152

0.50

1.41

1.6

1.4

—

Drug-induced adrenocortical insufficiency

138

0.43

1.41

1.7

1.3

—

Benign leiomyoma with endometriosis

818

0.76

1.41

1.4

—

Injury of muscle and tendon at lower leg level

897

0.77

1.41

1.3

1.4

—

Dependent personality disorder

237

0.54

1.41

1.1

1.5

—

Persons encountering health services in other circumstances

799

8570

0.92

1.40

1.4

—

Chronic nephritic syndrome

225

0.53

1.40

1.8

1.5

—

Other and unspecified injuries of shoulder and upper arm

385

0.64

1.40

1.3

1.5

—

Hepatomegaly and splenomegaly, not elsewhere classified

121

0.41

1.40

1.2

1.3

—

Benign neoplasm: Choroid

225

0.53

1.40

1.2

1.5

—

Trigeminal neuralgia

516

0.69

1.39

1.8

1.4

—

Other neurotic disorders

300

0.60

1.39

1.4

1.5

—

Other disorders of veins

351

3108

1.12

1.39

1.6

1.4

—

Other symptoms and signs involving the urinary system

621

0.72

1.39

1.6

1.4

—

Mandibular retrognathia

180

1530

1.18

1.38

1.4

—

Phakomatoses, not elsewhere classified

164

0.48

1.38

1.1

1.4

—

General symptoms and signs

2494

13054

0.96

1.38

1.5

1.4

—

Other and unspecified follicular disorders

549

0.70

1.38

1.6

1.4

—

Other symptoms and signs involving general sensations and perceptions

420

0.66

1.38

1.5

—

Exposure to smoke, fire and flames

223

0.53

1.38

1.3

1.5

—

Type 1 diabetes, strict definition, subgroup 2

0.00

1.38

0.0

1.3

—

Striking against or struck by other objects

570

6220

0.91

1.38

1.5

1.4

—

Intentional self-harm by smoke, fire and flames

0.00

1.37

0.0

1.3

—

Myeloproliferative diseases

287

0.59

1.37

1.4

1.5

—

Hyperfunction of pituitary gland

1211

0.80

1.37

1.4

—

Endometriosis in cutaneous scar

122

1.76

1.37

1.5

—

Secondary uncertain malignant neoplasm

480

0.69

1.37

1.2

1.4

—

Tuberous sclerosis 1

0.00

1.36

0.0

1.3

—

Total colectomy

430

0.67

1.35

1.6

1.4

—

Total colectomy operation

430

0.67

1.35

1.6

1.4

—

Viral hepatitis, IBD co-morbidity

1166

0.80

1.35

1.4

—

Toxic effects of substances chiefly nonmedicinal as to source

175

2048

0.85

1.34

1.3

1.4

—

Other diseases of blood and blood-forming organs

334

0.63

1.34

1.2

1.5

—

Amiodarone users

0.00

1.34

0.0

1.3

—

Keratitis

487

5351

0.91

1.34

1.4

1.5

—

Adenomyosis (Endometriosis of uterus)

147

1746

0.84

1.34

1.5

1.4

—

GI-bleeding

143

1705

0.84

1.34

1.5

1.4

—

Other diseases of the digestive system

142

1694

0.84

1.34

1.5

1.4

—

Clefts and syndromes for tooth agenesis exclusion, including avohilmo

713

0.74

1.33

1.6

1.4

—

Optic atrophy

146

0.47

1.33

1.6

1.4

—

Hypertensive heart and/or renal disease

114

0.46

1.33

1.1

1.5

—

Dysphagia

130

1562

0.83

1.33

1.5

1.4

—

Viral Sepsis

157

1854

0.84

1.32

1.5

1.4

—

Certolizumab pegol

707

1.28

1.32

1.4

1.5

—

Chronic rhinitis, nasopharyngitis and pharyngitis

472

5189

0.91

1.32

1.4

—

Suppurative and unspecified otitis media

1345

12592

0.94

1.32

1.5

1.4

—

Other disorders of glucose regulation and pancreatic internal secretion

1009

0.79

1.32

1.5

1.4

—

Benign neoplasm of other and unspecified female genital organs

429

1.34

1.31

1.4

—

Implicit viral Sepsis

157

1852

0.85

1.31

1.5

1.4

—

Other and unspecified drugs and medicaments

1019

0.79

1.31

1.6

1.4

—

Disorders of the thyroid gland

2351

14659

1.05

1.30

1.5

1.4

—

Malignant neoplasm of digestive organs

404

0.70

1.30

1.5

1.4

—

Trigger finger

1063

0.80

1.29

1.5

1.4

—

Other diseases of pericardium

174

0.51

1.29

1.2

1.4

—

ILD, hospital admission 2, with pulmonary infections

193

0.52

1.29

1.4

—

Other predominantly sexually transmitted diseases, not elsewhere classified

844

9028

0.93

1.28

1.5

1.4

—

Seropositive rheumatoid arthritis

151

1776

0.85

1.28

1.4

—

Other congenital malformations of skin

193

1667

1.17

1.28

1.4

—

Synovial hypertrophy, not elsewhere classified

190

0.51

1.28

1.3

1.5

—

Lymphoid leukaemia

243

0.57

1.28

1.9

1.4

—

Hypermetropia

139

1167

1.20

1.27

1.5

1.4

—

Complications of other internal prosthetic devices, implants and grafts

292

0.61

1.27

1.5

1.4

—

Secondary and unspecified malignant neoplasm of lymph nodes, including Hilmo

565

0.72

1.27

1.2

1.4

—

Other demyelinating diseases of the central nervous system

866

0.78

1.26

1.4

—

Other respiratory diseases principally affecting the interstitium

341

0.64

1.26

1.4

—

Wegener granulomatosis

115

0.43

1.26

1.8

1.4

—

Achalasia of cardia

115

0.43

1.26

2.2

1.4

—

Congenital deformities of feet

810

0.77

1.26

1.5

1.4

—

Retinal vascular disorders

191

0.52

1.25

1.2

1.5

—

Retinal vascular occlusion

191

0.52

1.25

1.2

1.5

—

Other noninfective gastroenteritis and colitis

304

3405

0.89

1.25

1.5

1.4

—

Mental disorders, not otherwise specified

205

2348

0.87

1.23

1.3

1.4

—

Abnormal weight loss

754

0.77

1.23

1.6

1.4

—

Acute gastritis

386

0.67

1.23

1.3

1.5

—

Abnormal findings in nipple discharge synovial fluid wound secretions

226

0.57

1.23

1.7

1.5

—

Early lumbar disc prolapse, operated

215

2456

0.87

1.23

1.6

1.4

—

Congenital malformations of the urinary system

113

935

1.22

1.23

1.5

1.4

—

Degeneration of macula and posterior pole

299

0.66

1.23

1.4

1.5

—

276

0.61

1.22

1.3

1.4

—

Mucosal proctocolitis

194

2233

0.86

1.22

1.5

1.4

—

Congenital malformations of the urinary system

105

863

1.23

1.22

1.5

1.4

—

Bitten or stung by nonvenomous insect and other nonvenomous arthropods

489

0.71

1.22

1.4

1.5

—

Malignant neoplasm of thyroid gland, including Hilmo

685

0.76

1.22

1.4

—

Acute peritonitis

289

0.62

1.22

1.3

1.5

—

Propionic acid derivatives

734

3976

0.93

1.22

1.5

1.4

—

Somnolence

225

0.57

1.22

1.5

1.4

—

Malignant neoplasm of eye, brain and central nervous system

300

0.63

1.21

1.1

1.4

—

Soft tissue disorders related to use, overuse and pressure

139

1643

0.84

1.21

1.4

—

Pulmonary heart disease, diseases of pulmonary circulation

103

1251

0.82

1.20

1.4

—

Osteonecrosis

188

0.53

1.20

1.3

1.4

—

Traumatic subdural haemorrhage

193

0.55

1.20

1.9

1.4

—

Hypokalaemia

650

0.75

1.20

1.6

1.4

—

Juvenile rheumatoid arthirtis

611

0.74

1.20

1.5

1.4

—

Other enthesopathy of foot (+metatarsalgia)

106

1281

0.82

1.20

1.4

—

Other hypertrichosis

110

0.43

1.20

1.6

1.5

—

Carcinoma in situ of cervix uteri, exocervix

129

0.45

1.20

2.2

1.4

—

Neurofibromatosis, type 2

0.00

1.19

0.0

1.3

—

Delayed milestone in childhood

224

0.59

1.19

1.3

—

Anti-inflammatory and antirheumatic products, non-steroids

735

3976

0.93

1.19

1.5

1.4

—

Bursitis of shoulder

171

0.52

1.18

1.4

1.5

—

Other sleep disorders

129

1529

0.84

1.18

1.4

—

Early onset COPD, excluding more controls

557

0.73

1.18

1.8

1.4

—

Cutaneous abscess, furuncle and carbuncle

410

4506

0.91

1.18

1.4

—

Epileptic seizures related to drugs

0.00

1.18

0.0

1.4

—

Benign neoplasm: Pituitary gland, craniopharyngeal duct

680

0.76

1.18

1.5

1.4

—

Psoriasis vulgaris

138

1627

0.85

1.18

1.6

1.4

—

Unspecified event, undetermined intent

392

0.68

1.18

1.3

1.5

—

Early onset COPD

557

0.74

1.18

1.8

1.4

—

Open wound of thorax

126

0.47

1.18

1.3

1.4

—

5-aminosalicylic acid

361

3991

0.90

1.18

1.5

1.4

—

Pleural effusion

262

0.61

1.18

1.5

—

Vulvovaginal ulceration/inflammation in other diseases

266

2371

1.14

1.17

1.6

1.4

—

Actinomycosis

0.00

1.17

0.0

1.2

—

Ulcerative rectosigmoiditis

1168

0.82

1.17

1.6

1.4

—

Malignant neoplasm of ovary, including Hilmo

322

0.65

1.17

1.4

—

Other disorders starting during childhood or adolecense, excluding more controls

204

2222

0.87

1.17

1.4

—

Other specified/unspecified disorders of synovium and tendon +Other specified/unspecified bursopathies

741

1.24

1.17

1.4

—

Panhypopituitarism

129

0.46

1.17

2.2

1.4

—

Other necrotizing vasculopathies (FG)

224

0.58

1.17

1.4

—

Explicit fungal Sepsis

0.00

1.17

0.0

1.5

—

Tetraplegia

0.00

1.17

0.0

1.3

—

Ganglion

355

3926

0.90

1.17

1.5

1.4

—

Shock, not elsewhere classified

0.00

1.16

0.0

1.4

—

Routine general health check-up of defined subpopulation

437

0.70

1.16

1.3

1.4

—

Mixed disorders of conduct and emotions, excluding more controls

109

1297

0.82

1.16

1.4

—

Disorders of lacrimal system

454

4949

0.91

1.15

1.4

—

Other disorders of carbohydrate metabolism

0.00

1.15

0.0

1.2

—

Personal history of other diseases and conditions

387

4230

0.90

1.15

1.4

—

Optic atrophy

155

0.51

1.15

1.6

1.4

—

Hypoparathyroidism

222

0.58

1.14

1.1

1.4

—

Optic neuritis

942

0.80

1.14

1.5

1.4

—

Other inflammation of eyelid

119

1415

0.84

1.14

1.3

1.4

—

Need for other prophylactic measures

437

0.71

1.14

1.2

1.4

—

Dissocial personality disorder

112

0.44

1.14

1.0

1.5

—

Monoarthritis, not elsewhere classified

449

1.30

1.13

1.5

1.4

—

Rosacea

135

1586

0.85

1.13

1.3

1.4

—

Visual field defects

540

0.74

1.12

1.5

1.4

—

Narcolepsy and cataplexy

164

0.53

1.12

1.2

1.4

—

Other noninflammatory disorders of vagina

182

1584

1.16

1.12

1.4

—

Hypothyroidism, other/unspecified

2102

14396

0.96

1.12

1.5

1.4

—

Other extrapyramidal and movement disorders in other diseases

153

1780

0.86

1.12

1.3

1.4

—

Secondary and unspecified malignant neoplasm of lymph nodes

424

0.70

1.11

1.2

1.4

—

Injuries to the thorax

360

3968

0.91

1.11

1.5

1.4

—

Alcohol abuse, main dg

188

2152

0.87

1.11

1.4

—

Cervical disc disorders

133

1564

0.85

1.11

1.4

—

Sulfasalazine

378

4155

0.91

1.11

1.4

—

Bilateral sagittal split ramus osteotomy operation

757

1.23

1.10

1.5

1.4

—

Other specified and unspecified strabismus

163

0.54

1.10

1.2

1.4

—

Assault by bodily force

137

1602

0.85

1.10

1.5

1.4

—

Attention to artificial openings

136

0.51

1.10

1.6

1.4

—

Chondromalacia

231

0.60

1.09

1.9

1.5

—

Glaucoma-related operations

139

0.50

1.09

1.4

1.5

—

Somnolence, stupor and coma

421

0.71

1.09

1.4

—

Acute posthaemorrhagic anaemia

163

0.55

1.08

1.8

1.5

—

Type 1 diabetes, strict definition

216

2433

0.88

1.08

1.3

1.4

—

Other effects of reduced temperature

2.22

1.08

1.9

1.4

—

Other and unspecified injuries of forearm

121

0.49

1.08

1.0

1.3

—

Bicornuate uterus

291

1.40

1.08

1.5

1.4

—

Pulmonary embolism

1136

0.83

1.08

1.5

1.4

—

Malignant neoplasm of brain, including Hilmo

385

0.70

1.07

1.1

1.4

—

Ankle and foot

124

0.47

1.07

1.5

1.4

—

Seropositive rheumatoid arthritis, wide

151

1751

0.86

1.07

1.4

—

Viral and other specified intestinal infections

784

8147

0.94

1.07

1.4

—

Blepharochalasis

350

0.69

1.06

1.4

—

Pulmonary heart disease

1134

0.83

1.06

1.5

1.4

—

Lichen ruber planus, wide definition including periferal and oral lichen planus

1123

0.83

1.06

1.3

1.4

—

Unspecified visual impairment (binocular)

123

0.48

1.06

1.3

1.5

—

Systemic sclerosis, icd10

179

0.55

1.06

1.5

1.4

—

Posteruptive colour changes of dental hard tissues

1.76

1.05

1.1

1.5

—

Mycoses

377

3436

1.10

1.05

1.6

1.4

—

Chronic viral hepatitis

955

0.81

1.05

1.4

—

Other secondary coxarthrosis

121

0.49

1.05

1.5

—

6-mercaptopurine

821

0.79

1.05

1.5

1.4

—

Diplopia

101

1208

0.83

1.05

1.5

1.4

—

Other disorders of lacrimal gland

370

4059

0.91

1.05

1.5

1.4

—

Other and unspecified epidermal thickening

312

0.67

1.05

1.4

—

Monoplegia

148

0.53

1.05

1.4

—

Depression

2203

14361

1.04

1.05

1.4

—

Non-allergic asthma (mode), excluding more controls

238

2645

0.89

1.05

1.4

—

Other malignant neoplasms of skin (=non-melanoma skin cancer)

422

0.76

1.04

1.5

1.4

—

Skin changes due to chronic exposure to nonionizing radiation

116

0.48

1.04

1.3

1.4

—

Anogenital herpesviral [herpes simplex] infection

267

2401

1.12

1.04

1.4

—

Other sexually transmitted chlamydial diseases

635

5938

1.08

1.04

1.5

1.4

—

Systemic sclerosis

178

0.56

1.04

1.5

—

Type 1 diabetes, definitions combined

235

2626

0.89

1.04

1.3

1.4

—

Recurrent or chronic depression

968

7205

0.94

1.04

1.4

—

Contact with blunt object, undetermined intent

106

0.46

1.04

1.8

1.4

—

Non-allergic asthma (mode)

238

2643

0.89

1.04

1.4

—

Malignant neoplasm of ovary

240

0.62

1.04

1.3

1.5

—

Contusion of ankle

831

0.80

1.03

1.5

1.4

—

Intentional self-harm by unspecified means

413

0.71

1.03

1.4

—

Injury of nerves and spinal cord at neck level

106

1.62

1.03

1.8

1.4

—

Polyneuropathies and other disorders of the peripheral nervous system

701

0.78

1.03

1.4

—

Sequelae of injuries, of poisoning and of other consequences of external causes

224

2520

0.89

1.03

1.4

—

Other disorders involving the immune mechanism, not elsewhere classified

287

0.66

1.03

1.6

1.4

—

Injury of intra-abdominal organs

357

0.69

1.02

1.7

1.4

—

Other superficial injuries of ankle and foot

157

0.56

1.02

1.3

1.5

—

Conductive hearing loss, unspecified

909

0.81

1.02

1.6

1.4

—

Other disorders of bone development and growth

0.00

1.02

0.0

1.3

—

Gingival hyperplasia

369

0.70

1.02

1.6

1.4

—

Acute pancreatitis (for exclusion)

943

0.81

1.02

1.4

—

Other papulosquamous disorders

108

0.46

1.02

1.2

1.5

—

Personal history of malignant neoplasm

530

0.75

1.02

1.3

1.4

—

Abnormal involuntary movements

119

1398

0.85

1.02

1.3

1.4

—

Crohn's disease of large intestine

819

0.80

1.02

1.6

1.4

—

887

9321

0.94

1.02

1.5

1.4

—

Neonatal aspiration syndromes

0.00

1.01

0.0

1.2

—

Rheumatoid arthritis, including avohilmo

306

3381

0.90

1.01

1.5

1.4

—

Asthma-related pneumonia or sepsis

322

3541

0.91

1.01

1.5

1.4

—

Asthma, hospital admissions 3, pneumonia

322

3541

0.91

1.01

1.5

1.4

—

Type 1 diabetes, strict (exclude DM2)

235

2621

0.89

1.01

1.3

1.4

—

Hypoglycaemia, other or unspecified

819

0.80

1.01

1.5

1.4

—

Ovarian dysfunction, other/unspecified

210

0.60

1.01

1.4

—

Carcinoma in situ of cervix uteri

453

4895

0.92

1.01

1.4

1.5

—

Valvular operations

214

0.61

1.01

1.4

—

Injury of muscle and tendon at wrist and hand level

1093

0.83

1.00

1.4

—

Heartburn

162

1411

1.15

1.00

1.5

1.4

—

Intentional self-harm by jumping or lying before moving object

0.00

1.00

0.0

1.3

—

Primary adrenocortical insufficiency

160

0.55

1.00

1.3

1.4

—

Enthesopathies of lower limb, excluding foot

216

2430

0.89

1.00

1.4

—

Non-Hodgkin lymphoma, all, including Hilmo

286

0.66

1.00

1.4

—

Follicular cysts of skin and subcutaneous tissue

151

1739

0.87

1.00

1.4

—

Other metabolic disorders

176

2004

0.87

1.00

1.4

—

Injuries to unspecified part of trunk, limb or body region

111

1308

0.84

1.00

1.4

—

Other/unspecified seropositive rheumatoid arthritis (ICD-10)

149

1718

0.87

1.00

1.4

—

Other/unspecified seropositive rheumatoid arthritis

149

1718

0.87

1.00

1.4

—

Pityriasis rubra pilaris

0.00

1.00

0.0

1.4

—

Osteosarcoma

0.00

0.99

0.0

1.4

—

Pilonidal cyst

152

1746

0.87

0.99

1.5

1.4

—

Other congenital malformations of nervous system

374

0.70

0.99

1.4

—

Sacroiliitis, not elsewhere classified

164

1435

1.15

0.99

1.4

—

Severe combined immunodeficiency [SCID] with reticular dysgenesis

0.00

0.99

0.0

1.4

—

Papillary adenocarcinoma of thyroid gland

436

0.73

0.99

1.4

—

Systemic sclerosis (FG)

175

0.57

0.99

1.5

—

Varicose veins of other sites

189

1.43

0.99

1.7

1.4

—

Carcinoma in situ of endometrium

0.00

0.98

0.0

1.5

—

Other specified/unspecified arthritis

330

3625

0.91

0.98

1.4

—

Other injuries of upper limb, level unspecified

174

0.57

0.98

1.8

1.4

—

Cystic fibrosis with intestinal manifestations

0.00

0.98

0.0

1.3

—

Other viral hepatitis

1121

0.83

0.98

1.4

—

ILD, hospital admissions

249

0.64

0.98

1.3

1.5

—

Other interstitial pulmonary diseases

249

0.64

0.98

1.3

1.5

—

Interstitial lung disease endpoints

249

0.64

0.98

1.3

1.5

—

Interstitial lung disease

249

0.64

0.98

1.3

1.5

—

Other disorders of the genitourinary system

459

0.74

0.98

1.3

1.4

—

Abnormal serum enzyme levels

936

0.82

0.98

1.6

1.4

—

Blindness or visual impairment, binocular

0.00

0.98

0.0

1.3

—

Other and unspecified mononeuropathies of upper limb

248

0.64

0.98

1.8

1.5

—

Viral hepatitis

1175

0.84

0.98

1.3

1.4

—

Scabies

682

0.79

0.98

1.5

1.4

—

Hirsutism, drug-induced

0.00

0.98

0.0

1.3

—

Eclampsia

1.82

0.98

1.6

1.5

—

Malignant neoplasm of retroperitoneum and peritoneum

0.00

0.98

0.0

1.5

—

Embedded teeth, including avohilmo

409

4433

0.91

0.98

1.4

—

Exposure to other specified electric current

501

0.75

0.97

1.6

1.4

—

Acute pancreatitis

937

0.82

0.97

1.4

—

LeFortI or BSSO operation

115

981

1.18

0.97

1.5

1.4

—

Postprocedural endocrine and metabolic disorders, not elsewhere classified

165

1882

0.87

0.97

1.4

—

Other and unspecified disorders involving the immune mechanism, not elsewhere classified

271

0.66

0.97

1.6

1.5

—

Disturbances of skin sensation

575

6164

0.93

0.97

1.5

1.4

—

Alopecia universalis

0.00

0.97

0.0

1.4

—

Malignant neoplasm of brain

271

0.66

0.97

1.1

1.4

—

Abscess of Bartholin gland

832

0.81

0.97

1.6

1.4

—

Constitutional tall stature

195

0.59

0.96

1.5

1.3

—

Asthma-related pneumonia

321

3520

0.91

0.96

1.4

—

Effects of foreign body entering through natural orifice

259

2876

0.90

0.96

1.4

—

Infective dermatitis

1131

0.84

0.96

1.6

1.4

—

Lichen planus, including avohilmo

914

0.82

0.96

1.3

1.4

—

Other abortion

261

1.38

0.96

1.3

—

Malignant neoplasm of bone and articular cartilage of limbs

0.00

0.96

0.0

1.4

—

Atopic conjunctivitis

921

0.82

0.96

1.4

1.5

—

Anuria and oliguria

0.00

0.95

0.0

1.3

—

1067

0.83

0.95

1.4

—

Fall on same level involving ice and snow

756

8031

0.94

0.95

1.4

—

Cervicocranial syndrome

107

1259

0.85

0.95

1.4

—

Allergic rhinitis

925

9647

0.94

0.95

1.4

—

Volume depletion

467

0.75

0.94

1.4

—

UC patients in KELA-register ( KELA 208 prior to 1994, or ICD K51)

288

3174

0.90

0.94

1.5

1.4

—

Superficial injury of hip and thigh

135

1558

0.86

0.94

1.5

1.4

—

Other abnormal findings of blood chemistry

511

0.76

0.94

1.1

1.4

—

Other primary thrombocytopenia

1.78

0.94

1.2

1.4

—

Balanced rearrangements and structural markers, not elsewhere classified

144

1.54

0.94

1.5

1.4

—

Chronic conjunctivitis

321

1.32

0.94

1.4

—

Other/unspecified soft tissue disorders related to use, overuse and pressure

339

0.70

0.94

1.3

1.4

—

Traumatic amputation of wrist and hand

118

0.51

0.94

1.3

1.4

—

therapeutic use

119

0.50

0.94

1.8

1.5

—

Arthropod-borne viral fevers and viral haemorrhagic fevers

178

2014

0.88

0.93

1.4

—

Mandibular hypoplasia

143

1.51

0.93

1.6

1.5

—

Other disorders of breast

287

2605

1.11

0.93

1.5

1.4

—

Additional codes for the location of defect, injury or illness

677

0.79

0.93

1.4

—

Corneal scars and opacities

196

0.61

0.93

1.5

—

Corneal ulcer

238

2646

0.90

0.92

1.5

1.4

—

Disorder of thyroid, unspecified

126

1.53

0.92

1.5

1.4

—

Keratitis and keratoconjunctivitis in other diseases classified elsewhere

256

0.66

0.92

1.4

1.5

—

Other disorders of eyelid

111

1237

0.85

0.92

1.5

1.4

—

Pyoderma

183

0.60

0.92

1.5

1.4

—

Malignant melanoma of skin

383

1.28

0.92

1.4

1.5

—

Superficial injury of ankle and foot, unspecified

126

0.54

0.92

1.1

1.4

—

Chronic pancreatitis

280

0.68

0.92

1.4

1.5

—

Iron deficiency anaemia secondary to blood loss (chronic)

908

0.82

0.91

1.6

1.4

—

Misadventures to patients during surgical and medical care

162

1422

1.14

0.91

1.5

1.4

—

Intentional self-harm by jumping from a high place

127

0.54

0.91

1.3

1.4

—

Haemangioma and lymphangioma, any site

112

957

1.18

0.91

1.4

—

Other female pelvic inflammatory diseases

250

2768

0.90

0.91

1.5

1.4

—

ICD-8 DM (Sub-endpoint used for defining DM endpoints)

195

0.61

0.91

1.3

1.4

—

Haemangioma, any site

101

856

1.19

0.91

1.5

1.4

—

Calcific tendinitis of shoulder

267

0.67

0.90

1.4

1.5

—

Pruritus

199

1773

1.13

0.90

1.5

1.4

—

Exposure to other and unspecified animate mechanical forces

716

0.80

0.90

1.4

—

CR(E)ST syndrome

103

0.48

0.90

1.6

1.5

—

Postmenopausal atrophic vaginitis

270

0.76

0.89

1.3

1.4

—

Malignant neoplasm of breast, HER-negative

695

0.80

0.89

1.3

1.4

—

Pedestrian injured in collision with car, pick-up truck or van

381

0.73

0.89

1.4

1.5

—

Maltreatment syndromes

130

1493

0.86

0.89

1.5

1.4

—

Polyarteritis nodosa and related conditions

156

0.57

0.89

1.3

1.5

—

Left bundle-branch block

102

0.49

0.89

1.6

1.4

—

Convergent concomitant strabismus

113

1312

0.85

0.89

1.5

1.4

—

Open wound of hip and thigh

483

0.76

0.89

1.6

1.4

—

Occupant of special all-terrain or other motor vehicle designed primarily for off-road use, injured in transport accident

127

0.55

0.89

1.6

1.5

—

Hodgkin lymphoma, hilmo

403

0.74

0.88

1.2

1.4

—

Lactose intolerance

549

0.78

0.88

1.4

—

Pedestrian injured in transport accident

880

0.83

0.88

1.4

—

Alopecia areata

548

0.78

0.88

1.6

1.4

—

Acute laryngitis and tracheitis

375

3994

0.92

0.87

1.5

1.4

—

DVT of lower extremities and pulmonary embolism

169

1902

0.88

0.87

1.5

1.4

—

Psoriatic and enteropathic arthropathies

1097

0.85

0.87

1.5

1.4

—

ILD, hospital admissions 3, with pneumonia sepsis

131

0.53

0.87

1.4

—

Malignant neoplasm of other connective and soft tissue, including Hilmo

168

0.59

0.86

1.2

1.4

—

Complications of internal orthopaedic prosthetic devices, implants and grafts

426

0.75

0.86

1.2

1.4

—

Pedal cyclist injured in transport accident

363

3938

0.92

0.86

1.5

1.4

—

Scleritis and episcleritis

736

0.81

0.86

1.4

—

Divergent concomitant strabismus

1105

0.85

0.86

1.5

1.4

—

Panniculitis affecting regions of neck and back

356

0.73

0.86

1.5

1.4

—

Viral conjunctivitis

743

1.20

0.86

1.4

—

Pneumothorax

287

0.69

0.86

1.3

1.4

—

Chronic laryngitis and laryngotracheitis

106

907

1.17

0.85

1.6

1.4

—

Other disorders of cornea

648

0.80

0.85

1.5

1.4

—

Chondropathies

218

2421

0.90

0.85

1.4

—

Atrial septal defect

532

0.78

0.85

1.6

1.4

—

Migraine without aura, drug-induced

261

0.68

0.85

1.4

1.5

—

Neurofibromatosis, type 1

113

0.52

0.85

1.2

1.4

—

Autonomic disorders

227

0.65

0.85

1.3

1.5

—

Metatarsalgia

100

1169

0.85

1.4

—

Ulcerative colitis (strict definition, require KELA)

277

3038

0.91

0.85

1.5

1.4

—

Atopic dermatitis, strict definition

1101

11279

0.95

0.85

1.4

—

Contusion of toe(s) without damage to nail

633

0.80

0.85

1.3

1.4

—

Atypical facial pain

502

0.77

0.85

1.6

1.4

—

Granuloma faciale [eosinophilic granuloma of skin]

0.00

0.84

0.0

1.2

—

Other disorders of thyroid

129

1.49

0.84

1.5

1.4

—

Oedema, not elsewhere classified

281

3039

0.91

0.84

1.5

1.4

—

Viral meningitis

717

1.20

0.84

1.5

1.4

—

Fistulae involving female genital tract

137

0.58

0.84

1.6

1.5

—

Dermatitis due to substances taken internally

842

0.83

0.84

1.5

1.4

—

Ulcerative colitis (strict definition, require KELA, min 2 HDR)

272

2983

0.91

0.84

1.5

1.4

—

Primary hyperparathyroidism

274

0.69

0.84

1.4

—

Juvenile arthritis (FINNGEN)

138

1568

0.87

0.84

1.5

1.4

—

Superficial injuries involving multiple body regions

455

0.76

0.83

1.4

—

Biological medicines for asthma

307

0.71

0.83

1.4

—

Other benign neoplasm of uterus: Corpus uteri

1.72

0.83

2.3

1.5

—

Malignant neoplasm of mesothelium and soft tissue

139

0.57

0.83

1.3

1.5

—

Speech disturbances, not elsewhere classified

445

0.76

0.83

1.5

1.4

—

Helminthiases

128

1119

1.16

0.83

1.4

—

Conotruncal defects

248

0.67

0.83

1.5

1.4

—

Parapsoriasis

258

1.33

0.83

1.4

—

Internal derangement of knee

497

5292

0.93

0.82

1.5

1.4

—

Other and unspecified local infections of skin and subcutaneous tissue

1047

0.85

0.82

1.4

1.5

—

Motorcycle rider injured in other and unspecified transport accidents

873

0.83

0.82

1.4

—

308

0.72

0.82

1.2

1.4

—

Chronic thyroiditis

1.74

0.82

1.4

1.5

—

Foreign body in genitourinary tract

188

0.63

0.82

1.2

1.4

—

Benign neoplasm: Parathyroid gland

1.89

0.82

1.2

1.5

—

Asthma mixed form (mode)

796

0.82

1.4

—

Other epidermal thickening

409

0.75

0.81

1.5

1.4

—

Dermatophytosis

910

9549

0.95

0.81

1.4

—

Other local infections of skin and subcutaneous tissue

1067

0.85

0.81

1.4

1.5

—

Atopic dermatitis, strict definition with reimbursement

1144

11529

0.95

0.81

1.4

—

Ulcerative enterocolitis

442

0.76

0.81

1.3

1.4

—

Sequelae of intentional self-harm, assault and events of undetermined intent

151

0.58

0.81

1.3

1.4

—

Ependymoma

0.00

0.81

0.0

1.3

—

Mandibular retrognathia AND surgery (BSSO)

574

1.22

0.81

1.4

—

Contact with nonpowered hand tool

306

0.72

0.81

1.5

1.4

—

Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system

0.00

0.81

0.0

1.6

—

Visual impairment including blindness (binocular or monocular)

476

0.77

0.80

1.4

—

Other immunodeficiencies

147

0.60

0.80

1.4

1.5

—

Caries of dentine

252

2693

0.91

0.80

1.5

1.4

—

Rash and other nonspecific skin eruption

1044

0.85

0.80

1.7

1.4

—

Asthma mixed form (mode), excluding more controls

794

0.83

0.80

1.4

—

Chronic inflammatory disorders of orbit

0.00

0.80

0.0

1.3

—

Other and unspecified pemphigus

0.00

0.80

0.0

1.3

—

Cholesteatoma of middle ear

294

0.71

0.80

1.4

—

Actinomycosis

0.00

0.80

0.0

1.2

—

Injury of blood vessels at lower leg level

0.00

0.80

0.0

1.2

—

Other psoriatic arthropathies

751

0.82

0.79

1.5

1.4

—

Toxic effect of corrosive substances

100

0.49

0.79

1.4

—

Other and unspecified iron deficiency

473

4415

1.07

0.79

1.5

1.4

—

Other and unspecified pemphigoid

0.00

0.79

0.0

1.3

—

Type 1 diabetes, strict definition, subgroup 1

216

2378

0.90

0.79

1.3

1.4

—

Hereditary hypogammaglobulinemia

0.00

0.79

0.0

1.2

—

Acute alcohol intoxication ICD-9

0.00

0.79

0.0

1.2

—

Malignant neoplasm of bone and articular cartilage of other and unspecified sites

0.00

0.79

0.0

1.1

—

Viral haemorrhagic fevers, not elsewhere classified/unspecified

166

1860

0.89

0.79

1.5

1.4

—

Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis

2.31

0.79

1.2

1.4

—

Spasmodic torticollis

304

0.72

0.79

1.2

1.4

—

Other and unspecified water transport accidents

0.00

0.78

0.0

1.3

—

Other/unspecified enthesopathies of lower limb, excluding foot

922

0.84

0.78

1.3

1.4

—

Severe visual impairment, binocular

0.00

0.78

0.0

1.2

—

Deficiency of other B group vitamins

0.50

0.78

2.4

1.4

—

Disorders of refraction and accommodation

626

6602

0.94

0.78

1.5

1.4

—

Cervical root disorders

0.00

0.78

0.0

1.2

—

Carcinoma in situ of breast, intraductal

246

0.69

0.78

1.2

1.4

—

Family history of other specific disorders

369

1.27

0.77

1.6

1.4

—

Psoriasis (vulgaris), strict definition

257

0.70

0.77

1.8

1.5

—

Cramp and spasm

616

0.81

0.77

1.3

1.4

—

Erythema intertrigo

126

0.55

0.77

1.3

1.4

—

Delayed puberty

266

0.70

0.77

1.6

1.4

—

Carcinoma in situ of skin

0.50

0.77

2.0

1.5

—

Early lumbar disc prolapse operation

221

2434

0.90

0.77

1.6

1.4

—

Foreign body on external eye

101

1169

0.86

0.77

1.4

—

Other specified and unspecified disorders of iris and ciliary body

1.74

0.77

1.2

1.4

—

Protozoal diseases

174

0.63

0.77

1.5

—

ILD, hospital admissions 1, main diag only

222

0.67

0.77

1.3

1.5

—

Abrasion of teeth

374

4029

0.93

0.77

1.4

—

Other and unspecified thalassaemias

1.71

0.77

1.4

—

Hypertrophy of bone

1.72

0.76

1.4

—

Subjective visual disturbances

351

3789

0.92

0.76

1.5

1.4

—

Cirrhosis, broad definition used in the article https://doi.org/10.1101/594523

210

0.67

0.76

1.2

1.4

—

Pneumonia due to other infectious organisms, not elsewhere classified

233

0.68

0.76

1.6

1.5

—

Vitamin B12 deficiency anaemia

303

0.72

0.76

1.5

1.4

—

Other and/or unspecified nontoxic goitre

461

0.78

0.76

1.7

1.4

—

Aspergillosis

0.00

0.76

0.0

1.3

—

Right ventricular outflow tract obstruction

160

0.61

0.76

1.3

1.4

—

Arnold-Chiari syndrome

355

0.74

0.76

1.4

—

Carbimazole or st.post thyroidectomy, condition for graves disease

345

3194

1.08

0.76

1.4

—

Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

720

7490

0.95

0.75

1.5

1.4

—

Foreign body in ear

357

0.75

1.4

—

Hypoplasia of dental enamel, prenatal , including avohilmo

109

0.53

0.75

1.3

—

Cerebral aneurysm, nonruptured

370

0.75

1.5

—

Congenital malformations of cardiac septa

1033

0.86

0.74

1.5

1.4

—

Congenital malformations of heart and great arteries

179

1928

0.90

0.74

1.5

1.4

—

Crohn's disease patients in KELA-register (KELA code 209, or 208 with ICD K50)

120

1365

0.87

0.74

1.5

1.4

—

Septal defects

1002

0.85

0.74

1.5

1.4

—

Dermatitis herpetiformis

133

1.44

0.74

1.6

1.4

—

Cardiomyopathy

403

0.77

0.74

1.7

1.4

—

Lactose intolerance, other/unspecified

446

0.78

0.74

1.4

1.5

—

Respiratory tuberculosis, confirmed

1.64

0.73

1.8

1.5

—

Other congenital malformations of heart

117

1.48

0.73

1.9

1.3

—

Respiratory tuberculosis, bacteriologically and histologically confirmed

1.64

0.73

1.8

1.5

—

Accidental poisoning by and exposure to other gases and vapours

1.64

0.73

1.2

1.4

—

Injury of nerves at wrist and hand level

446

0.78

0.73

1.3

1.4

—

Developmental endpoint to exclude non autoimmune-cases from E4_HYTHY_AI_STRICT

487

4571

1.07

0.73

1.5

1.4

—

Malignant neoplasm of breast, ER-negative, including Hilmo

894

0.85

0.73

1.4

—

Other factor of the environment

159

0.62

0.73

2.1

1.4

—

Use of interferon beta-1a

500

0.79

0.73

1.3

1.5

—

Weight loss

991

0.85

0.73

1.5

1.4

—

Injury of cranial nerves

1.63

0.73

1.2

1.4

—

Typhoid and paratyphoid fevers

2.03

0.73

1.4

1.2

—

Endocarditis

136

0.59

0.73

1.3

1.5

—

Mixed conductive and sensorineural hearing loss

502

0.80

0.73

1.7

1.4

—

Pediculosis, acariasis and other infestations

774

0.84

0.72

1.5

1.4

—

Malignant neoplasm of skin

762

0.86

0.72

1.5

1.4

—

Disorders of vitreous body and globe

142

1534

0.89

0.72

1.5

1.4

—

Injuries to the ankle and foot

1805

15531

1.03

0.72

1.4

—

Specific development disorders of scholastic skills

136

1506

0.88

0.72

1.3

1.5

—

Other necrotizing vasculopathies

276

0.72

0.71

1.5

1.4

—

Myopia

363

3895

0.93

0.71

1.5

1.4

—

Convalescence

572

1.19

0.71

1.6

1.4

—

Congenital malformations of pulmonary and tricuspid valves

157

0.62

0.71

1.2

1.4

—

Fracture of neck

287

0.73

0.71

1.8

1.5

—

Episcleritis

631

0.82

0.71

1.3

1.4

—

Torticollis

342

0.75

0.71

1.4

—

Cyst of spleen

1.74

0.71

1.7

1.4

—

Lifestyle-related condition

142

0.63

0.71

2.2

1.4

—

Immunodeficiencies

532

0.80

0.71

1.6

1.4

—

Myalgia

486

5165

0.94

0.70

1.6

1.4

—

Pityriasis rosea

196

1.36

0.70

1.3

1.5

—

Arthropathic psoriasis

837

0.85

0.70

1.5

1.4

—

Malignant neoplasm of colon

182

0.66

0.70

1.3

1.4

—

Benign neoplasm: Connective and other soft tissue of upper limb, including shoulder

354

0.76

0.70

1.4

—

Benign neoplasm: Vagina

152

1.40

0.70

1.4

—

Other and unspecified trigeminal disorders

144

0.62

0.70

1.4

1.5

—

Acute generalized exanthematous pustulosis

586

0.81

0.70

1.6

1.4

—

Abnormalities of gait and mobility

521

0.80

0.70

1.3

1.4

—

Benign neoplasm: Rectum, anus and anal canal

372

1.24

0.70

1.4

—

Benign neoplasm: Caecum

143

1.40

0.70

1.5

1.4

—

Whooping cough

393

1.24

0.69

1.8

1.4

—

Dystonia

520

0.80

0.69

1.1

1.4

—

Benign neoplasm: Skin of other and unspecified parts of face

721

1.17

0.69

1.5

1.4

—

Mandibular prognathia AND surgery (LeFortI or BSSO), including avohilmo

238

0.70

0.69

1.5

1.4

—

Other embolism and thrombosis

782

0.84

0.69

1.4

—

HSIL lesion of the cervix uteri, vagina or vulva

836

8741

0.95

0.69

1.5

1.4

—

Evidence of alcohol involvement determined by blood alcohol level

227

0.70

0.69

1.5

1.4

—

Oral leukoplakia and other epithelial disorders of tongue and oral cavity , including avohilmo

331

0.75

0.69

1.8

1.5

—

Congenital lens malformations

0.54

0.69

2.0

1.4

—

Synovial cyst of popliteal space [Baker]

353

0.76

0.69

1.3

1.4

—

Personal history of medical treatment

119

0.58

0.69

1.6

1.3

—

Melanocytic naevi of ear and external auricular canal

1.52

0.68

1.2

1.5

—

Other specified and unspecified disorders of eye and adnexa

341

0.76

0.68

1.5

1.4

—

Exposure to other and unspecified man-made environmental factors

258

1.29

0.68

1.4

—

Impingement syndrome of shoulder

618

0.82

0.68

1.6

1.4

—

Adenocarcinoma and papilloma adenocarcinoma of rectum

1.53

0.68

1.3

—

Open wound of neck

0.54

0.68

2.2

1.3

—

Other and unspecified disorders of pigmentation

0.52

0.68

1.2

1.4

—

Symptoms and signs involving emotional state

626

0.82

0.68

1.2

1.4

—

Traumatic subarachnoid haemorrhage

118

0.59

0.68

1.1

1.4

—

Psoriatic arthropathies

790

0.85

0.67

1.5

—

Varus deformity, not elsewhere classified

0.53

0.67

1.0

1.5

—

Benign neoplasm: Other/unspecified site

0.54

0.67

1.8

1.4

—

Congenital malformations of the circulatory system

203

2159

0.91

0.67

1.5

1.4

—

Right bundle-branch block

121

0.58

0.67

1.6

1.4

—

Brain medulloblastoma

0.00

0.67

0.0

1.6

—

Brain medulloblastoma, including Hilmo

0.00

0.67

0.0

1.5

—

Thalassaemia

112

1.48

0.67

1.5

1.4

—

Melanocytic naevi of scalp and neck

458

1.21

0.67

1.5

1.4

—

Crohn's disease NAS

1013

0.86

0.67

1.6

1.4

—

Acute nasopharyngitis (common cold)

107

1208

0.88

0.67

1.5

1.4

—

Pre-eclampsia superimposed on chronic hypertension

181

1.37

0.67

1.2

1.4

—

Idiopathic hypercalciuria

1.80

0.66

1.4

1.3

—

Other special examinations and investigations of persons without complaint or reported diagnosis

1470

7185

1.04

0.66

1.5

1.4

—

Other specified/unspecified disorders of bone/cartilage

167

0.66

1.6

1.4

—

Crohn disease

217

2369

0.91

0.66

1.5

1.4

—

Injury of nerves and spinal cord at thorax level

1.61

0.66

1.3

—

Other orthopaedic follow-up care

461

0.80

0.66

1.6

1.4

—

Congenital stenosis of pulmonary valve

129

0.61

0.65

1.3

1.4

—

Other and unspecified rosacea

905

0.86

0.65

1.2

1.4

—

Generalized skin eruption due to drugs and medicaments

526

0.81

0.65

1.6

1.4

—

Other disorders of pigmentation

316

0.76

0.65

1.5

1.4

—

Crohn disease (strict definition, require KELA)

115

1297

0.88

0.65

1.5

1.4

—

Certain zoonotic bacterial diseases

178

0.67

0.65

1.3

1.4

—

GASTRO-related operations

2512

12269

1.03

0.65

1.5

1.4

—

Any gastric operation

2512

12269

1.03

0.65

1.5

1.4

—

Pollen allergy

676

7001

0.95

0.65

1.4

—

Type1 diabetes, definitions combined, early onset

206

2240

0.91

0.65

1.3

1.4

—

Sleepwalking [somnambulism]

105

0.55

0.65

1.5

1.4

—

Pedal cyclist injured in collision with motor vehicle

623

0.83

0.65

1.6

1.4

—

Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care

745

1.16

0.65

1.6

1.4

—

Vitiligo

172

1.36

0.65

1.6

1.4

—

Dislocation, sprain and strain of joints and ligaments at neck level

406

4321

0.94

0.65

1.4

—

Basal cell carcinoma

381

0.82

0.65

1.5

1.4

—

Caught, crushed, jammed or pinched in or between objects

753

0.85

0.65

1.5

1.4

—

Endometriosis ASRM stages 3,4

526

5556

0.94

0.65

1.3

1.4

—

IgA nephropathy (IgA glomerulonephritis)

224

0.71

0.64

1.3

1.5

—

Other congenital musculoskeletal deformities

113

1.47

0.64

1.7

1.4

—

Early complications of trauma

371

0.78

0.64

1.5

1.4

—

!Aliquae complicationes praecoces traumatis

371

0.78

0.64

1.5

1.4

—

Enterocolitis due to Clostridium difficile

613

0.83

0.64

1.5

1.4

—

All dysplastic lesions of the cervix uteri

1159

11910

0.96

0.64

1.4

—

Superficial injury of head

296

3186

0.93

0.64

1.4

—

Congenital malformations, deformations and chromosomal abnormalities

1570

15422

0.97

0.64

1.5

1.4

—

Benign neoplasm: Spinal meninges

1.73

0.64

1.4

1.2

—

Dementia in other diseases classified elsewhere

127

0.63

0.64

1.5

—

Localized skin eruption due to drugs and medicaments

153

0.65

0.64

1.6

1.4

—

Erythema nodosum

392

0.79

0.64

1.6

1.4

—

Malignant melanoma of skin, including Hilmo

505

1.19

0.63

1.4

—

Peripheral retinal degeneration

181

1.33

0.63

1.4

1.5

—

Obesity, other/unspecified

844

8087

1.05

0.63

1.7

1.4

—

Amoebiasis

101

0.59

0.63

1.8

1.4

—

Primary amenorrhea

452

0.79

0.63

1.5

1.4

—

Basal cell carcinoma, including avohilmo

438

0.83

0.63

1.5

1.4

—

Crohn disease (strict definition, require KELA, min 2 HDR)

115

1293

0.88

0.63

1.5

1.4

—

Stenosis and insufficiency of lacrimal passages

676

0.84

0.63

1.3

1.4

—

Unstable angina pectoris

0.58

0.63

1.3

1.5

—

Fetal death of unspecified cause

1.73

0.63

2.4

1.4

—

Other benign neoplasms of connective and other soft tissue

901

0.86

0.62

1.4

—

Benign neoplasm of other and unspecified endocrine glands

944

0.87

0.62

1.5

1.4

—

Respiratory tuberculosis, confirmed and not-confirmed

1.52

0.62

1.8

1.4

—

Respiratory tuberculosis

1.52

0.62

1.8

1.4

—

Cardiomyopathy (excluding other)

223

0.72

0.62

1.6

1.4

—

Mixed connective tissue disease

718

0.85

0.62

1.5

1.4

—

Delirium, not induced by alcohol and other psychoactive substances

211

0.71

0.62

1.5

1.4

—

Benign neoplasm: Scapula and long bones of upper limb

130

1.40

0.62

1.2

1.4

—

Disorders of porphyrin and bilirubin metabolism

105

0.57

0.62

1.8

1.4

—

Disorders of puberty, all

639

0.83

0.62

1.4

—

Crossbite

121

1253

0.89

0.62

1.4

—

Other juvenile arthritis

132

1468

0.89

0.62

1.5

1.4

—

Amblyopia ex anopsia

806

1.15

0.62

1.6

1.4

—

Distal bite

717

1.16

0.62

1.4

—

Complicated migraine, drug-induced

0.00

0.62

0.0

1.3

—

Ulcer of oesophagus

103

0.58

0.62

1.3

1.5

—

Benign neoplasm: Long bones of lower limb

489

0.81

0.62

1.5

1.4

—

Other and unspecified iridocyclitis

533

0.82

0.62

1.4

—

Otorrhagia

1.68

0.61

1.8

1.6

—

Alcoholic liver disease

104

0.58

0.61

1.0

1.4

—

Dislocation, sprain and strain of joints and ligaments of shoulder girdle

279

3005

0.93

0.61

1.5

1.4

—

Autoimmune polyglandular failure

0.00

0.61

0.0

1.3

—

Other disorders of iris and ciliary body

182

1.33

0.61

1.3

1.5

—

Desensitization to allergens

162

1782

0.90

0.61

1.4

—

Temporomandibular joint disorders, including avohilmo

1584

15150

1.03

0.61

1.5

1.4

—

Allergic colitis

648

1.17

0.61

1.3

1.4

—

Spondyloarthritis

272

2522

1.08

0.61

1.4

—

Pedestrian injured in other and unspecified transport accidents

139

0.64

0.61

1.3

1.5

—

Salpingitis and oophoritis

145

1608

0.90

0.61

1.4

—

General hospital and personal-use devices associated with adverse incidents

0.00

0.61

0.0

1.4

—

Convergence insufficiency and excess

483

1.20

0.61

1.6

1.4

—

Diseases of the ear and mastoid process

2722

13995

0.98

0.61

1.5

1.4

—

Bacterial intestinal infections, IBD co-morbidities

130

1450

0.89

0.61

1.5

1.4

—

Sixth [abducent] nerve palsy

187

0.69

0.61

1.5

—

Other encephalitis

334

0.77

0.61

1.7

1.4

—

Glucosamine medication

150

0.69

0.61

1.7

1.5

—

Myositis ossificans

0.00

0.61

0.0

1.4

—

Pain associated with micturition

155

1402

1.11

0.61

1.5

1.4

—

Stomatitis and related lesions

323

3456

0.93

0.61

1.5

1.4

—

Dislocations, sprains and strains involving multiple body regions

0.00

0.61

0.0

1.3

—

Mandibular prognathia

344

0.78

0.61

1.4

—

Generalized pustular psoriasis

0.00

0.61

0.0

1.0

—

Other specified/unspecified disorders of middle ear and mastoid

0.00

0.61

0.0

1.3

—

Psoriatic arthropathies, ICD10

781

0.86

0.61

1.5

1.4

—

Benign intracranial hypertension

484

0.81

0.61

1.5

1.4

—

Encephalitis

356

0.78

0.61

1.6

1.4

—

Cutaneous autosensitization

0.00

0.61

0.0

1.6

—

Induced delusional disorder

0.00

0.61

0.0

1.4

—

Symptoms and signs involving the skin and subcutaneous tissue

1174

11896

0.96

0.60

1.5

1.4

—

Defect, injury or illness of skull

0.00

0.60

0.0

1.4

—

Benign neoplasm: Mediastinum

0.00

0.60

0.0

1.1

—

Female infertility, uterine origin

111

0.61

0.60

1.3

1.4

—

Family history of malignant neoplasm

229

2112

1.09

0.60

1.5

1.4

—

Livedoid vasculitis

0.00

0.60

0.0

1.3

—

Ectropion of eyelid

0.00

0.60

0.0

1.5

—

Acrodermatitis continua

0.00

0.60

0.0

1.5

—

Ankylosis of joint

0.00

0.60

0.0

1.3

—

Malignant neoplasm of rectum, including Hilmo

1.48

0.60

1.4

1.3

—

Injury of muscle and tendon at forearm level

209

0.71

0.60

1.5

1.4

—

Severe mental retardation

0.00

0.60

0.0

1.4

—

Congenital malformations of larynx

0.00

0.60

0.0

1.4

—

Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity

356

0.78

0.60

1.5

1.4

—

Glaucoma secondary to drugs

0.00

0.60

0.0

1.2

—

Polyarthritis, unspecified

311

0.77

0.60

1.3

1.4

—

Benign neoplasm: Bones of skull and face

114

1.42

0.60

1.6

1.4

—

Hyperkinetic disorders (excl. ADHD)

416

0.80

0.60

1.5

1.4

—

Sequelae of other external causes

491

1.19

0.59

1.3

1.4

—

Other secondary gonarthrosis

151

0.66

0.59

1.7

1.4

—

Codes for special purposes

1203

11604

1.04

0.59

1.4

—

Unspecified misadventure during surgical and medical care

390

1.21

0.59

1.7

1.4

—

HSIL lesion of the cervix uteri

822

8556

0.96

0.59

1.5

1.4

—

Diagnoses used for exclusion with ILD

1078

0.88

0.59

1.5

1.4

—

Bronchitis, not specified as acute or chronic

693

0.85

0.59

1.4

—

Other forms of systemic lupus erythematosus

112

0.62

0.59

1.6

1.4

—

Anomalies of pupillary function

409

0.80

0.59

1.5

1.4

—

Provisional assignment of new diseases of uncertain etiology

1202

11596

1.04

0.59

1.4

—

Other injuries of spine and trunk, level unspecified

111

0.62

0.59

1.3

1.4

—

Follow-up examination after treatment for conditions other than malignant neoplasms

1032

7090

0.96

0.59

1.5

1.4

—

Abnormal pulmonary venous return

0.00

0.59

0.0

1.3

—

Explicit Sepsis

427

4224

0.94

0.59

1.5

1.4

—

Coronary artery bypass grafting

0.00

0.59

0.0

1.3

—

Chondrosarcoma, including Hilmo

0.00

0.58

0.0

1.4

—

Guttate psoriasis

219

0.72

0.58

1.3

1.4

—

Ankyloglossia

579

0.83

0.58

1.7

1.4

—

Bullous keratopathy

0.00

0.58

0.0

1.4

—

Leiomyosarcoma, including Hilmo

0.00

0.58

0.0

1.2

—

Folate deficiency anaemia

0.00

0.58

0.0

1.1

—

Osteomyelitis

310

0.77

0.58

1.5

1.4

—

Mature T/NK-cell lymphomas, hilmo

0.00

0.58

0.0

1.3

—

Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck

265

0.75

0.58

1.4

1.5

—

Benign neoplasm: Skin of upper limb, including shoulder

173

0.69

0.58

1.4

—

Other mycoses, not elsewhere classified/unspecified

230

0.73

0.58

1.1

1.5

—

Burn and corrosion of shoulder and upper limb, except wrist and hand

196

0.71

0.58

1.2

1.4

—

Asthma and allergy

479

4981

0.95

0.58

1.3

1.4

—

Benign neoplasm: Parotid gland

387

0.80

0.58

1.5

1.4

—

Other and unspecified types of non-Hodgkin lymphoma, hilmo

115

0.61

0.58

1.6

1.4

—

Mycoses

1830

15480

1.03

0.58

1.5

1.4

—

Marfan's syndrome

0.57

2.6

1.5

—

Allergic asthma (mode), excluding more controls

743

7584

0.96

0.57

1.4

—

Injuries involving multiple body regions

582

0.84

0.57

1.4

—

Other pulmonary heart/vessel disease

173

0.69

0.57

1.1

1.5

—

Malignant neoplasm of bladder, including Hilmo

1.70

0.57

1.5

1.3

—

Intermittent heterotropia

164

1792

0.91

0.57

1.4

—

Benign neoplasm: Skin of lower limb, including hip

184

0.70

0.57

1.5

—

Other and unspecified urticaria

410

4340

0.94

0.57

1.4

—

Artificial opening status

207

0.72

0.57

1.7

1.4

—

Overjet

492

1.18

0.56

1.6

1.4

—

Carcinoma in situ of uteri, other/unspecified

1.47

0.56

1.6

1.4

—

Allergic asthma (mode)

743

7581

0.96

0.56

1.4

—

Other disorders of binocular movement

645

1.16

0.56

1.5

1.4

—

Other diseases of hard tissues of teeth

776

3843

1.05

0.56

1.4

—

Other and unspecified bullous disorders

0.56

1.8

1.4

—

All dysplastic lesions of the cervix uteri, vagina or vulva

1191

12115

0.97

0.56

1.4

—

≡ Risteys

R13

FinnGen R12 + FinRegistry

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

First trimester maternal screen panel - Serum or Plasma

Coding

Definition

OMOP mapping QC

Cohort

Year of birth distribution

Age at first measurement

Age at last measurement

Age at start of registry

Duration from first to last measurement

Statistics

Number of measurements over the years

Number of measurements per person

Distribution of lab values

Value range per person

LabWAS