Endometriosis in cutaneous scar

N14_ENDOMETRIOSIS_SKIN_SCAR

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

only females

293218

2. Check conditions

None

293218

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 N80.6
  • Hospital discharge: ICD-9 6176
  • Cause of death: ICD-10 N80.6
  • Cause of death: ICD-9 6176

2 out of 7 registries used, show all original rules.

129

4. Check minimum number of events

None

129

5. Include endpoints

None

129

6. Filter based on genotype QC (FinnGen only)

125

Control definitions (FinnGen only)

Control exclude
N14_FEMALEGENNONINF

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
N80
Name in latin
Endometriosis cicatricis cutaneae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 700 700 -
Only index persons 683 683 -
Unadjusted period prevalence (%)
Whole population 0.02 0.02 -
Only index persons 0.03 0.03 -
Median age at first event (years)
Whole population - 36.97 -
Only index persons - 36.92 -

-FinnGen-

Key figures

All Female Male
Number of individuals 125 125 -
Unadjusted period prevalence (%) 0.04 0.04 -
Median age at first event (years) 36.86 36.86 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
129
Matched controls
1290
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
N80.6
ICD-10 Finland
Endometriosis in cutaneous scar
+∞
151.7
114
*
N80.9
ICD-10 Finland
Endometriosis, unspecified
423.8
33.5
32
*
N80.3
ICD-10 Finland
Endometriosis of pelvic peritoneum
+∞
29.3
27
*
TLC00
NOMESCO Finland
Insertion of intrauterine device
12.1
25.0
28
29
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
6.0
23.0
78
263
N80.0
ICD-10 Finland
Endometriosis of uterus
+∞
21.4
20
*
JAA10
NOMESCO Finland
Excision of lesion of abdominal wall
+∞
21.4
20
*
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
5.7
21.4
62
181
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
10.1
21.3
27
33
N80.89
ICD-10 Finland
Endometriosis with other specified or multiple localization
+∞
20.3
19
*
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
8.2
19.7
30
46
N80.1
ICD-10 Finland
Endometriosis of ovary
207.3
18.0
18
*
O34.2
ICD-10 Finland
Maternal care due to uterine scar from previous surgery
5.7
17.2
40
94
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
4.7
17.1
61
205
6176A
ICD-9 Finland
Endometriosis in scar of skin
+∞
17.0
16
*
N95.1
ICD-10 Finland
Menopausal and female climacteric states
+∞
17.0
16
*
LEF03
NOMESCO Finland
Posterior colporrpahy with sutures for primary rectocele
+∞
16.0
15
*
N97.9
ICD-10 Finland
Female infertility, unspecified
44.1
15.9
19
5
N81.6
ICD-10 Finland
Rectocele
41.4
14.9
18
5
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
13.8
14.6
25
22
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
18.6
14.5
22
14
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
5.1
14.5
38
98
O82.0
ICD-10 Finland
Delivery by elective caesarean section
6.1
14.1
28
56
N92.0
ICD-10 Finland
Excessive and frequent menstruation with regular cycle
6.4
13.9
26
49
N84.0
ICD-10 Finland
Polyp of corpus uteri
+∞
12.7
12
*
JAH01
NOMESCO Finland
Laparoscopy
15.9
11.4
18
13
N81.1
ICD-10 Finland
Cystocele
47.8
11.1
13
*
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
4.6
11.1
31
83
JAL21
NOMESCO Finland
Laparoscopic excision or destruction of lesion of peritoneum
119.3
10.6
11
*
XW3AT
NOMESCO Finland
Biopsy of other superficial organ with ultrasound guidance
+∞
10.6
10
*
LAC01
NOMESCO Finland
Laparoscopic excision of ovarian cyst
35.8
10.5
13
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
3.4
10.4
65
300
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
3.3
10.0
66
314
LCA06
NOMESCO Finland
Biopsy of endometrium
9.3
9.8
20
25
N97.8
ICD-10 Finland
Female infertility of other origin
107.6
9.5
10
*
JN2CG
NOMESCO Finland
Extensive MRI examination of lower part of abdoment with high intensity magnet
107.6
9.5
10
*
JAP01
NOMESCO Finland
Laparoscopic freeing of adhesions in the peritoneal cavity
107.6
9.5
10
*
N80.4
ICD-10 Finland
Endometriosis of rectovaginal septum and vagina
107.6
9.5
10
*
D25.9
ICD-10 Finland
Leiomyoma of uterus, unspecified
5.3
9.2
20
43
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
8.7
9.0
19
25
B02AA02
ATC
tranexamic acid; systemic
4.1
9.0
29
86
O82.10
ICD-10 Finland
Delivery by emergency caesarean section
3.8
9.0
32
102
TLC02
NOMESCO Finland
Simple extraction of IUD
8.4
8.8
19
26
LA2AE
NOMESCO Finland
Ultrasound examination of ovarian cyst
+∞
8.4
8
*
QBE99
NOMESCO Finland
Other excision or repair of lesion of skin of trunk
35.8
8.2
10
*
Z35.0
ICD-10 Finland
Supervision of pregnancy with history of infertility
23.8
8.2
11
5
R22.2
ICD-10 Finland
Localized swelling, mass and lump, trunk
8.3
8.0
17
23
LC2HE
NOMESCO Finland
Hystero-salpingography with ultrasound
16.4
7.9
12
8
N80
ICD-10 Finland
Endometriosis
47.9
7.8
9
*
N81.2
ICD-10 Finland
Incomplete uterovaginal prolapse
84.8
7.5
8
*
LAA10
NOMESCO Finland
Percutaneous or transvaginal puncture and recovery of oocyte
+∞
7.4
7
*
N80.5
ICD-10 Finland
Endometriosis of intestine
+∞
7.4
7
*
LEF00
NOMESCO Finland
Anterior colporraphy with sutures for primary cystocele
+∞
7.4
7
*
LBF01
NOMESCO Finland
Laparoscopic perfusion of Fallopian tube
+∞
7.4
7
*
N92.1
ICD-10 Finland
Excessive and frequent menstruation with irregular cycle
8.8
7.3
15
19
N92.6
ICD-10 Finland
Irregular menstruation, unspecified
7.1
7.2
17
27
ZXE10
NOMESCO Finland
More than one and less than three hours
2.8
7.1
51
244
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
9.1
7.0
14
17
ZXD10
NOMESCO Finland
Scheduled procedure
2.7
6.9
55
278
R2110
NOMESCO Finland
Giving the first information
4.6
6.8
17
41
LAF01
NOMESCO Finland
Laparoscopic unilateral salpingo-oophorectomy
24.0
6.8
9
*
JN3BD
NOMESCO Finland
Extensive abdominal CT
6.0
6.8
18
34
LC2DE
NOMESCO Finland
Demanding ultrsound examination of uterus, parametrium and lower part of abdomen with speciel methods
7.6
6.7
15
22
ULC02
NOMESCO Finland
Hysteroscopy
10.9
6.7
12
12
JN3AD
NOMESCO Finland
Abdominal CT examination
4.5
6.6
17
42
N97.0
ICD-10 Finland
Female infertility associated with anovulation
+∞
6.3
6
*
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
3.6
6.2
22
69
G03GA06
ATC
follitropin beta; parenteral
9.3
6.2
12
14

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
36
93
4.98
13.65
1.4
1.3
—
—
—
0
0
71
369
3.06
8.95
2.1
1.7
—
—
—
0
0
18
43
4.70
7.28
2.7
3.6
28.00
71.50
u/ml
0.41
18
43
52
265
2.61
6.31
2.2
1.8
—
—
—
0
0
12
19
6.84
5.22
1.8
1.3
41.17
80.53
pmol/l
0.63
12
19
19
72
2.92
3.94
3.3
6.7
105.11
105.01
mmol/l
0.03
19
72
121
1053
3.40
3.69
13.0
8.9
19.82
19.03
mg/l
0.10
105
760
39
217
2.14
3.59
1.9
1.7
0.71
0.82
mg/l
0.24
30
155
21
89
2.62
3.54
1.4
1.4
—
—
—
0
0
19
78
2.68
3.40
1.3
1.4
48.48
22.70
iu/l
1.05
14
68
88
675
1.96
3.11
5.0
3.6
—
—
—
0
0
13
46
3.03
3.02
1.4
1.3
—
—
—
0
0
27
141
2.16
2.88
3.3
2.1
6.70
8.61
e6/l
0.40
27
124
33
188
2.01
2.80
2.8
2.7
—
—
—
0
0
46
297
1.85
2.70
5.9
7.0
1.02
1.07
inr
0.64
12
87
40
254
1.83
2.44
2.0
2.2
—
—
—
0
0
6
12
5.18
2.43
1.5
1.1
—
—
—
0
0
86
687
1.76
2.32
8.2
6.2
67.33
72.87
u/l
1.20
81
653
8
24
3.48
2.22
3.1
1.5
13.38
13.08
%
—
8
24
22
118
2.04
2.18
2.5
2.4
13.62
14.73
umol/l
0.30
22
109
76
602
1.64
1.98
2.6
2.8
—
—
—
0
0
41
281
1.67
1.88
1.4
1.2
0.63
1.32
u/ml
0.54
14
84
45
317
1.64
1.85
2.2
1.8
93.65
93.86
pmol/l
0.01
23
175
36
244
1.66
1.70
1.5
1.3
2.16
2.09
g/l
0.12
27
156
113
1013
1.93
1.68
4.1
3.3
1.51
1.56
mmol/l
0.78
108
959
113
1014
1.92
1.66
4.0
3.3
4.89
4.85
mmol/l
0.13
108
958
114
1027
1.95
1.64
4.1
3.6
2.95
2.91
mmol/l
0.17
109
973
7
26
2.79
1.60
4.0
2.5
0.69
0.62
%
—
7
26
8
33
2.52
1.56
1.5
1.3
—
—
—
0
0
13
65
2.11
1.55
1.0
1.2
—
—
—
0
0
18
102
1.89
1.54
1.1
1.2
245.95
95.81
iu/ml
—
8
48
62
488
1.52
1.53
4.4
3.9
6.50
6.38
mmol/l
0.16
55
432
15
80
1.99
1.52
1.5
1.4
—
—
—
0
0
30
201
1.64
1.48
4.0
2.5
—
—
—
0
0
39
280
1.56
1.45
4.5
2.8
60.30
54.61
e6/l
0.05
33
171
54
417
1.51
1.44
4.7
5.4
10.43
9.15
umol/l
0.55
48
394
7
29
2.49
1.41
4.0
2.4
0.93
1.38
%
—
7
29
25
163
1.66
1.36
3.4
3.3
—
—
—
0
0
17
101
1.79
1.27
1.1
1.1
—
—
—
0
0
35
255
1.51
1.20
4.9
2.3
—
—
—
0
0
10
50
2.08
1.20
3.5
4.6
0.58
2.92
mmol/l
—
10
39
5
20
2.56
1.16
1.8
1.1
—
—
—
0
0
10
51
2.04
1.14
3.5
4.5
—
—
—
0
0
61
500
1.42
1.14
6.9
5.3
1.86
2.10
e9/l
0.96
53
446
13
74
1.84
1.11
1.1
2.1
4.01
8.57
e9/l
0.53
13
64
15
91
1.73
1.06
1.7
1.5
5029.02
1663.28
u/l
—
6
34
54
440
1.39
1.02
13.1
6.6
0.00
0.00
e9/l
0.50
44
357
57
469
1.39
1.01
6.8
3.9
0.00
0.00
estimate
-0.00
14
87
15
93
1.69
0.99
1.2
1.3
—
—
—
0
0
106
972
1.51
0.98
3.8
3.0
1.29
1.16
mmol/l
0.49
99
916
52
424
1.38
0.97
2.6
2.3
—
—
—
0
0
24
169
1.52
0.96
3.0
2.1
—
—
—
0
0
5
101
0.47
0.94
4.6
1.7
—
—
—
0
0
16
103
1.63
0.93
1.3
1.2
—
—
—
0
0
57
475
1.36
0.92
5.1
2.8
0.00
0.00
estimate
-0.00
15
90
14
87
1.68
0.92
1.9
1.2
—
—
—
0
0
65
557
1.34
0.86
9.0
8.7
4.02
3.97
e9/l
0.07
57
485
11
65
1.76
0.85
3.2
3.2
—
—
—
0
0
57
484
1.32
0.78
7.2
5.4
0.04
0.04
e9/l
0.11
50
422
12
75
1.66
0.78
5.8
2.6
—
—
—
0
0
32
250
1.37
0.76
5.4
3.1
0.00
0.00
estimate
-0.00
15
86
5
24
2.13
0.75
1.0
1.1
—
—
—
0
0
120
1149
1.64
0.75
12.8
8.3
—
—
—
0
0
56
478
1.30
0.73
5.2
2.8
0.00
0.00
estimate
-0.00
12
85
5
25
2.04
0.73
1.0
1.2
—
—
—
0
0
5
25
2.04
0.73
1.8
1.2
261.68
149.69
u/ml
—
5
16
33
262
1.35
0.71
2.0
2.6
9.95
16.15
ng/l
1.69
11
124
15
103
1.52
0.68
1.3
1.7
—
—
—
0
0
56
482
1.29
0.68
7.3
5.3
0.49
0.53
e9/l
0.74
50
421
26
201
1.37
0.66
3.7
3.3
1.02
1.02
kg/l
—
5
27
32
256
1.33
0.65
1.3
1.7
—
—
—
0
0
5
29
1.75
0.64
1.2
2.1
—
—
—
0
0
41
342
1.29
0.62
1.8
1.7
—
—
—
0
0
8
50
1.64
0.62
1.6
1.7
—
—
—
0
0
58
506
1.27
0.62
7.3
6.1
0.16
0.17
e9/l
0.33
53
445
42
354
1.28
0.59
1.6
1.8
—
—
—
0
0
25
196
1.34
0.58
3.6
3.0
17.64
50.25
mg/l
1.30
20
120
6
36
1.70
0.57
1.3
1.3
—
—
—
0
0
11
74
1.53
0.55
1.2
1.2
—
—
—
0
0
9
65
1.41
0.52
1.2
2.8
—
—
—
0
0
12
165
0.70
0.50
1.3
1.2
—
—
—
0
0
102
963
1.28
0.50
15.6
11.5
14.20
14.28
%
0.05
102
948
25
201
1.30
0.50
4.1
3.7
2.53
9.73
mg/mmol
1.44
20
125
7
47
1.52
0.48
1.6
1.1
—
—
—
0
0
5
31
1.64
0.43
1.0
1.2
—
—
—
0
0
5
35
1.45
0.40
2.0
2.3
—
—
—
0
0
50
449
1.19
0.37
7.6
6.0
—
—
—
0
0
9
71
1.29
0.37
1.2
1.2
—
22.96
—
0
8
6
41
1.49
0.36
3.7
8.4
1.02
0.64
%
—
6
41
6
41
1.49
0.36
3.7
8.4
89.40
94.79
%
—
6
41
6
41
1.49
0.36
3.7
8.4
1.37
1.19
%
—
6
41
6
41
1.49
0.36
1.0
1.0
—
—
—
0
0
13
101
1.32
0.33
1.3
1.2
—
—
—
0
0
7
52
1.37
0.32
1.6
1.2
—
—
—
0
0
7
53
1.34
0.31
5.4
7.8
—
—
—
0
0
27
234
1.19
0.29
4.0
2.9
—
—
—
0
0
21
178
1.21
0.28
1.5
1.4
—
—
—
0
0
5
40
1.26
0.22
7.2
6.6
23.00
25.41
mmol/l
—
5
40
34
309
1.14
0.21
1.7
1.6
—
—
—
0
0
10
80
1.27
0.21
1.1
1.5
—
—
—
0
0
11
90
1.24
0.20
2.9
2.2
373.36
370.82
nmol/l
0.02
11
82
10
81
1.25
0.19
2.5
2.1
—
22.51
—
0
7
7
58
1.22
0.18
1.3
1.2
—
—
—
0
0
6
79
0.75
0.16
1.8
1.4
—
—
—
0
0
6
79
0.75
0.16
1.7
1.4
—
—
—
0
0
6
80
0.74
0.16
1.7
1.5
—
—
—
0
0
20
185
1.10
0.09
1.5
1.3
12.29
26.04
iu/ml
—
7
52
13
136
0.95
0.00
2.2
3.1
62.40
244.96
ng/l
—
5
77
14
144
0.97
0.00
1.8
1.6
—
—
—
0
0
18
183
0.98
0.00
1.5
1.3
1.46
11.58
u/ml
—
7
71
24
237
1.02
0.00
7.3
7.2
—
—
—
0
0
0
9
0.00
0.00
0.0
6.6
—
0.68
—
0
9
0
9
0.00
0.00
0.0
1.8
—
—
—
0
0
0
9
0.00
0.00
0.0
1.8
—
6.10
—
0
9
0
9
0.00
0.00
0.0
1.6
—
1552.67
—
0
9
6
59
1.02
-0.00
1.3
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
59
1.02
-0.00
1.7
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
5.0
—
5.12
—
0
6
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
59
1.02
-0.00
1.7
1.2
—
—
—
0
0
5
49
1.02
-0.00
1.6
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
7.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
6
59
1.02
-0.00
1.7
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
12.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
90.88
—
0
5
0
6
0.00
-0.00
0.0
4.0
—
11.20
—
0
6
0
8
0.00
-0.00
0.0
2.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.4
—
1.34
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
5.95
—
0
5
0
6
0.00
-0.00
0.0
5.0
—
9.17
—
0
6

Mortality – FinRegistry

Association

Association between endpoint N14_ENDOMETRIOSIS_SKIN_SCAR and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have N14_ENDOMETRIOSIS_SKIN_SCAR.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: N14_ENDOMETRIOSIS_SKIN_SCAR – Endometriosis in cutaneous scar

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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