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Any prescribed medicine buy

ANY_ATC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Medicine purchases: ATC ANY

1 out of 7 registries used, show all original rules.

517176

4. Check minimum number of events

Min. number of events 3
517176

5. Include endpoints

None

517176

6. Filter based on genotype QC (FinnGen only)

517176

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

No data for upset plot.

No data for upset table.

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 517176 292501 224675
Unadjusted period prevalence (%) 99.42 99.70 99.05
Median age at first event (years) 35.41 31.35 40.68

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
220
224
9.13
105.23
6.7
2.8
87.9
116.7
u/l
3.37
212
209
112
52
15.46
84.17
5.7
2.3
59.7
40.0
ng/l
0.34
74
30
179
184
8.02
82.70
3.9
1.8
—
—
—
0
0
208
259
7.07
81.79
3.6
1.7
9.3
8.4
mm/h
0.43
195
238
305
567
6.20
81.39
14.3
4.7
26.6
28.7
mg/l
0.31
248
319
242
392
5.82
72.70
5.4
1.7
40.6
34.8
mmol/mol
11.88
230
372
195
257
6.40
71.59
5.2
6.1
6.5
5.5
mmol/l
7.64
183
226
252
432
5.63
71.05
4.2
1.9
2.0
2.0
mu/l
0.25
233
402
316
686
5.33
67.84
15.3
3.7
80.6
66.2
umol/l
7.76
316
686
206
309
5.71
65.92
3.7
1.6
15.0
14.4
pmol/l
1.96
188
273
318
716
5.12
64.47
13.7
4.2
—
—
—
0
0
71
21
22.21
62.75
4.0
1.2
12.2
32.8
mg/mmol
0.31
45
13
128
120
7.79
62.06
4.9
1.8
2.8
2.3
ug/l
0.34
116
108
252
478
4.99
61.78
4.2
1.7
5.9
5.4
mmol/l
8.35
232
448
113
91
8.81
61.21
10.5
2.8
1.2
1.2
inr
0.02
34
25
199
309
5.39
60.72
4.6
2.5
—
—
—
0
0
178
248
5.76
60.71
7.9
4.6
3.9
3.9
e9/l
0.00
153
191
260
524
4.76
58.71
3.7
1.8
1.2
1.1
mmol/l
1.17
244
501
272
570
4.71
58.57
4.3
1.8
2.7
3.2
mmol/l
9.66
253
531
267
558
4.65
57.41
3.9
1.8
1.4
1.5
mmol/l
2.39
250
530
67
22
19.82
57.05
3.0
1.1
1108.8
7670.6
mg/l
0.66
40
12
266
562
4.57
56.14
4.0
1.8
4.5
5.0
mmol/l
11.28
250
535
162
229
5.45
53.71
5.7
3.9
2.0
2.7
e9/l
4.40
139
184
160
225
5.46
53.29
6.3
4.1
0.2
0.2
e9/l
0.13
136
177
157
221
5.41
52.12
5.7
3.9
0.6
0.6
e9/l
0.95
132
175
158
226
5.33
51.53
6.2
3.9
30.6
37.7
%
5.46
150
219
156
221
5.36
51.37
5.7
3.9
0.0
0.0
e9/l
0.55
132
174
155
220
5.34
50.89
5.9
3.9
54.3
47.4
%
4.77
147
215
153
215
5.37
50.75
6.4
4.0
8.7
8.1
%
1.42
144
209
152
215
5.32
50.00
6.1
3.9
3.1
3.0
%
0.13
140
208
150
211
5.33
49.59
6.0
4.0
0.6
0.6
%
0.04
140
206
75
44
11.21
49.09
4.9
1.9
—
—
—
0
0
343
963
4.20
47.46
19.7
5.7
242.4
259.3
e9/l
4.08
336
874
343
966
4.18
47.13
19.7
5.7
4.5
4.7
e12/l
3.38
337
874
343
969
4.16
46.81
19.9
5.7
6.9
6.9
e9/l
0.06
336
877
137
193
5.17
44.81
9.7
9.3
1.2
1.2
mmol/l
1.30
122
184
132
183
5.20
43.82
8.1
9.7
1.2
1.2
mmol/l
1.61
122
176
81
66
8.12
42.83
3.6
1.4
2.4
2.4
mmol/l
0.18
73
57
78
62
8.28
41.95
2.9
1.6
0.9
0.6
ug/l
2.22
48
31
142
221
4.69
41.32
3.5
2.3
0.0
0.0
estimate
0.00
26
33
91
92
6.64
40.55
2.0
1.5
80.1
97.0
pmol/l
2.30
49
54
98
108
6.16
40.49
2.0
1.7
—
—
—
0
0
55
26
13.38
40.03
1.7
1.2
386.5
456.4
pmol/l
0.44
47
20
142
227
4.56
39.93
10.4
5.8
0.0
0.1
e9/l
0.50
112
176
78
67
7.65
39.56
2.8
3.3
8.4
8.5
mmol/l
0.04
70
62
84
80
6.96
39.28
4.5
2.6
—
—
—
0
0
138
222
4.49
38.38
5.1
3.5
0.0
0.0
estimate
0.00
26
36
138
222
4.49
38.38
3.8
2.4
0.0
0.0
estimate
0.00
23
36
112
153
5.06
37.33
6.6
5.0
—
—
—
0
0
45
16
17.46
36.89
1.6
1.5
1105.2
1332.6
nmol/l
—
37
10
80
82
6.40
35.02
2.9
2.0
—
—
—
0
0
74
72
6.68
33.82
3.8
1.8
7.4
7.4
ph
—
15
7
109
160
4.67
33.33
3.0
1.9
—
—
—
0
0
67
60
7.17
32.71
2.7
2.0
1.2
1.3
mg/l
0.05
55
52
95
128
4.97
31.83
2.5
2.8
667.6
116.3
e6/l
0.40
76
81
280
818
3.12
31.81
14.5
5.8
39.7
40.1
%
0.37
233
715
106
159
4.53
31.51
3.3
3.4
53.5
117.4
e6/l
0.48
77
87
124
214
4.04
31.05
4.2
3.8
—
—
—
0
0
62
54
7.30
30.89
1.5
1.2
21.2
21.1
nmol/l
0.01
55
47
83
107
5.08
29.01
3.4
2.2
0.0
0.0
estimate
0.00
23
33
57
50
7.18
28.18
2.6
3.5
205.9
447.8
ng/l
0.63
37
30
120
227
3.63
26.20
2.5
2.5
126.4
57.6
ug/l
2.66
114
214
79
107
4.79
26.09
3.1
2.1
—
—
—
0
0
73
97
4.83
24.56
3.2
1.9
1.0
1.0
kg/l
0.44
11
15
105
189
3.73
24.43
2.8
1.6
—
—
—
0
0
72
96
4.81
24.12
1.7
2.8
2.9
2.8
mg/l
0.08
67
88
34
17
12.12
23.87
1.3
1.4
—
—
—
0
0
79
118
4.33
23.24
2.5
2.7
0.2
0.2
e6/l
0.31
61
70
44
36
7.52
22.84
1.8
1.9
—
—
—
0
0
79
122
4.18
22.29
2.4
2.5
—
—
—
0
0
58
68
5.35
22.13
3.5
2.0
—
—
—
0
0
35
22
9.65
21.65
1.2
1.0
5.7
1.5
u/ml
—
12
8
74
112
4.23
21.36
8.6
4.4
—
—
—
0
0
46
47
6.02
19.92
2.3
2.0
15.6
16.0
umol/l
0.06
40
47
54
66
5.09
19.72
2.8
2.8
582.5
551.3
mosm/kgh2o
0.31
49
56
30
17
10.61
19.67
1.4
1.2
—
—
—
0
0
80
145
3.54
18.15
2.7
2.2
—
—
—
0
0
37
35
6.41
17.08
1.3
1.3
—
—
—
0
0
26
15
10.34
16.85
2.3
3.1
3.5
4.9
e9/l
—
20
10
69
119
3.66
16.72
1.4
1.3
2.3
1.7
g/l
1.00
39
52
45
55
5.01
16.39
2.3
1.8
154.4
73.8
ug/g
1.00
37
49
22
11
11.85
15.35
6.3
1.3
—
—
—
0
0
54
83
4.02
15.17
1.8
1.2
—
—
—
0
0
69
128
3.39
15.04
1.2
1.4
0.5
3.3
u/ml
1.09
18
19
37
42
5.33
14.49
1.7
1.5
—
—
—
0
0
34
36
5.69
14.21
5.5
11.5
0.6
0.7
mmol/l
0.02
25
24
65
121
3.36
14.07
3.8
2.2
—
—
—
0
0
22
13
10.02
14.04
3.0
1.4
—
—
—
0
0
22
5
26.07
13.74
1.3
1.4
—
—
—
0
0
52
91
3.51
12.27
1.8
1.6
1.6
1.5
mmol/l
0.04
46
82
23
19
7.17
11.78
1.4
1.2
—
—
—
0
0
21
16
7.74
11.40
2.3
3.2
0.0
0.4
e6/l
0.58
21
16
20
15
7.85
10.97
3.4
2.7
—
—
—
0
0
30
37
4.84
10.80
1.2
1.2
—
—
—
0
0
28
35
4.76
9.94
1.3
1.2
—
—
—
0
0
36
56
3.86
9.94
2.3
1.9
—
—
—
0
0
82
221
2.33
9.00
1.7
1.7
—
—
—
0
0
20
21
5.60
8.41
3.9
2.1
—
—
—
0
0
83
239
2.17
7.78
2.0
1.7
—
—
—
0
0
17
19
5.23
6.75
6.8
19.5
1.4
1.1
%
0.53
17
19
15
15
5.83
6.58
1.9
1.2
37.6
38.5
nmol/l
0.06
15
15
17
20
4.97
6.43
6.8
18.8
0.7
0.7
%
0.04
17
20
37
79
2.80
6.41
6.0
6.4
—
—
—
0
0
37
80
2.76
6.27
6.0
6.2
1.8
0.7
mmol/l
1.03
27
57
15
16
5.46
6.22
9.0
21.9
—
—
—
0
0
13
12
6.30
6.09
2.4
1.3
—
—
—
0
0
12
10
6.97
6.07
3.7
1.9
—
—
—
0
0
12
6
11.61
6.06
2.3
2.8
—
—
—
0
0
45
110
2.46
6.05
1.5
1.7
—
—
—
0
0
11
5
12.75
5.79
2.5
10.8
—
—
—
0
0
24
43
3.28
5.51
3.1
2.7
59.8
62.9
e9/l
0.18
18
25
35
79
2.63
5.51
6.9
7.8
—
—
—
0
0
64
191
2.04
5.44
1.9
1.6
—
—
—
0
0
16
21
4.44
5.42
1.6
1.2
—
—
—
0
0
11
6
10.62
5.40
2.3
3.3
1.6
1.3
mmol/l
—
11
6
12
8
8.70
5.35
1.0
1.1
—
—
—
0
0
11
7
9.10
5.05
4.3
2.7
—
—
—
0
0
13
15
5.03
5.01
1.2
1.2
—
—
—
0
0
15
20
4.37
5.00
7.5
18.8
93.4
95.9
%
1.24
15
20
6
0
+∞
4.96
1.2
0.0
35.2
—
mu/l
—
6
0
6
0
+∞
4.96
1.0
0.0
—
—
—
0
0
14
18
4.52
4.85
8.4
20.2
23.4
24.7
mmol/l
0.72
14
18
10
6
9.64
4.75
1.4
1.0
—
—
—
0
0
10
6
9.64
4.75
1.1
1.2
1.1
1.2
g/l
—
10
6
9
5
10.39
4.46
1.9
1.4
—
—
—
0
0
25
54
2.72
4.29
1.1
1.2
—
—
—
0
0
5
0
+∞
4.13
1.6
0.0
—
—
—
0
0
5
0
+∞
4.13
1.8
0.0
26.8
—
g/l
—
5
0
5
0
+∞
4.13
2.8
0.0
—
—
—
0
0
9
6
8.66
4.12
1.0
1.0
—
—
—
0
0
12
16
4.34
4.00
1.2
1.4
—
—
—
0
0
10
9
6.42
3.88
2.4
1.4
3.6
3.3
mmol/l
—
10
9
10
9
6.42
3.88
1.5
1.4
—
—
—
0
0
10
9
6.42
3.88
2.5
1.6
288.2
573.3
mg/l
—
10
9
9
7
7.42
3.83
1.3
1.3
—
—
—
0
0
8
5
9.22
3.82
1.6
2.0
—
—
—
0
0
10
12
4.81
3.71
2.9
4.7
—
—
—
0
0
49
156
1.87
3.51
1.8
1.6
—
—
—
0
0
17
34
2.91
3.35
2.8
2.1
11368.4
1994.4
u/l
—
5
17
11
16
3.97
3.33
1.7
1.1
—
—
—
0
0
9
9
5.77
3.32
1.8
4.7
—
—
—
0
0
8
7
6.58
3.24
1.0
1.1
0.2
0.2
g/l
—
8
7
12
20
3.47
3.08
3.8
2.6
—
—
—
0
0
14
27
3.00
2.93
6.5
2.7
22.3
22.2
s
0.02
14
27
10
15
3.85
2.93
1.3
1.0
—
—
—
0
0
8
9
5.12
2.78
1.6
1.0
—
—
—
0
0
29
84
2.02
2.73
12.0
10.0
—
—
—
0
0
9
12
4.32
2.72
1.8
2.1
—
—
—
0
0
9
12
4.32
2.72
1.8
2.1
—
—
—
0
0
9
12
4.32
2.72
1.8
2.1
—
—
—
0
0
9
12
4.32
2.72
1.8
2.1
—
—
—
0
0
11
19
3.34
2.70
25.5
5.6
—
—
—
0
0
7
7
5.75
2.67
1.3
1.7
—
—
—
0
0
30
89
1.97
2.66
12.1
9.7
24.1
23.4
mmol/l
0.53
30
89
36
115
1.84
2.59
1.5
1.2
—
—
—
0
0
6
5
6.89
2.59
3.7
1.4
—
—
—
0
0
6
5
6.89
2.59
1.3
1.0
—
—
—
0
0
6
6
5.74
2.35
1.5
5.8
1.9
1.6
mmol/l
—
6
6
7
9
4.47
2.27
3.9
1.8
—
—
—
0
0
8
12
3.83
2.25
2.3
2.0
—
—
—
0
0
20
55
2.11
2.18
1.6
1.1
—
—
—
0
0
8
13
3.54
2.10
1.3
1.2
—
—
—
0
0
5
5
5.73
2.02
3.6
3.0
19.3
21.6
ug/l
—
5
5
12
27
2.56
1.98
1.4
1.1
224.4
340.4
miu/ml
—
5
12
8
14
3.28
1.96
1.3
1.2
—
—
—
0
0
5
6
4.77
1.81
2.6
2.5
—
—
—
0
0
6
9
3.82
1.79
3.0
20.3
—
—
—
0
0
8
16
2.87
1.72
1.3
2.8
—
—
—
0
0
7
13
3.09
1.67
1.0
1.2
—
—
—
0
0
6
10
3.44
1.64
4.5
1.9
—
—
—
0
0
5
7
4.09
1.63
1.4
1.1
—
—
—
0
0
22
71
1.80
1.60
1.7
1.8
—
—
—
0
0
7
15
2.68
1.45
1.4
1.0
—
—
—
0
0
15
45
1.92
1.36
1.6
1.4
—
—
—
0
0
6
13
2.64
1.28
1.8
1.3
—
—
—
0
0
11
31
2.04
1.18
2.8
1.7
—
—
—
0
0
14
44
1.83
1.14
1.6
1.3
—
—
—
0
0
14
44
1.83
1.14
1.6
1.3
—
—
—
0
0
13
41
1.82
1.05
1.1
1.1
—
—
—
0
0
6
14
2.45
0.98
3.8
2.6
—
—
—
0
0
6
16
2.15
0.90
1.0
1.0
—
—
—
0
0
10
31
1.85
0.86
1.6
1.3
—
—
—
0
0
5
12
2.38
0.79
1.2
1.0
—
—
—
0
0
16
59
1.56
0.79
1.1
1.2
—
—
—
0
0
5
13
2.20
0.76
1.4
3.0
—
—
—
0
0
16
62
1.48
0.66
1.1
1.2
—
—
—
0
0
16
62
1.48
0.66
1.2
1.2
—
—
—
0
0
16
62
1.48
0.66
1.1
1.2
—
—
—
0
0
16
63
1.46
0.62
1.1
1.2
—
—
—
0
0
0
6
0.00
0.22
0.0
1.2
—
—
—
0
0
0
6
0.00
0.22
0.0
1.5
—
—
—
0
0
5
37
0.77
0.08
1.4
1.5
—
—
—
0
0
9
48
1.07
0.07
1.0
1.0
17.0
19.7
mmol/l
—
9
48
9
49
1.05
0.07
1.0
1.0
—
—
—
0
0
13
72
1.03
0.00
1.0
1.0
11.8
8.1
mu/l
0.81
13
64
0
5
0.00
0.00
0.0
2.8
—
20.5
—
0
5

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: ANY_ATC – Any prescribed medicine buy

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).