Risteys ·

OMOP concept ID	Test name	Measurement unit (harmonized unit)	N people	N records	Missing measurement value	Harmonized value distribution
3030981	u-lieriöt	e6/l (e6/l)	11612	29132	0.00%
3030981	u-hyalie	e6/l (e6/l)	4896	15278	0.00%
3030981	u-hyalier	e6/l (e6/l)	4178	11255	0.00%
3030981	u-lieriöt	— (—)	1006	1406	100.00%	Distribution not available
3030981	u-hyalie	— (—)	333	467	100.00%	Distribution not available

LabWAS

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

Other bacterial diseases

4026

14432

2.00

320.37

3.8

2.5

0.40

0.25

e6/l

6.79

3951

14015

Persons encountering health services in other circumstances, wide

5132

14703

1.87

314.03

3.3

2.5

0.30

0.27

e6/l

0.51

5003

14286

Cystitis

3648

11134

2.08

313.29

3.6

2.3

0.28

0.29

e6/l

0.08

3530

10798

Persons encountering health services for specific procedures and health care

4981

14454

2.22

307.65

3.6

2.4

0.28

e6/l

0.04

4883

13984

Persons encountering health services for other counselling and medical advice, not elsewhere classified

4790

14549

1.94

307.65

3.4

2.5

0.29

0.27

e6/l

0.34

4661

14135

Bacterial infection, other or unspecified

2562

9938

2.47

307.65

4.1

2.6

0.44

0.25

e6/l

6.34

2529

9703

Speech therapy

1494

5188

3.15

307.65

2.7

2.8

0.19

0.30

e6/l

3.13

1474

5049

Other disorders of urethra and urinary system

3032

10562

2.24

307.65

3.9

2.3

0.27

0.29

e6/l

0.27

2969

10241

Fitting and adjustment of other devices

2155

6390

3.45

307.65

3.2

2.6

0.32

0.29

e6/l

0.23

2127

6238

Persons with potential health hazards related to communicable diseases

2382

5994

4.33

307.65

3.4

2.4

0.22

0.25

e6/l

0.66

2345

5773

Contact with and exposure to communicable diseases

2038

4635

4.85

307.65

3.0

2.4

0.21

0.26

e6/l

0.85

2006

4445

Care involving use of rehabilitation procedures

2858

12167

2.34

307.65

3.2

2.4

0.20

0.28

e6/l

3.24

2815

11780

Other diseases of urinary system

4597

12906

2.08

307.65

3.6

2.4

0.26

0.28

e6/l

0.46

4482

12529

Acute tubulo-interstitial nephritis

2768

11167

2.31

307.65

4.2

2.2

0.39

0.25

e6/l

4.33

2710

10845

Provisional assignment of new diseases of uncertain etiology

2301

8654

2.84

307.65

3.4

2.6

0.25

0.27

e6/l

0.25

2245

8400

Renal tubulo-interstitial diseases

4493

13865

2.63

307.65

4.7

2.2

0.37

0.25

e6/l

4.85

4418

13437

Unspecified haematuria

2236

6843

3.02

307.65

4.3

2.3

0.24

0.31

e6/l

2.06

2198

6699

Genitourinary diseases

2543

5062

2.61

307.65

3.4

1.7

0.22

0.30

e6/l

1.94

2488

4919

Codes for special purposes

2306

8665

2.85

307.65

3.4

2.6

0.25

0.27

e6/l

0.26

2250

8411

Renal failure

2355

8506

2.73

307.65

5.8

2.6

0.34

0.28

e6/l

0.96

2332

8337

Other symptoms and signs involving the urinary system

1470

1608

13.55

307.65

5.6

2.3

0.11

0.33

e6/l

6.09

1460

1574

Chronic kidney disease

1785

6048

3.24

307.65

6.6

2.7

0.23

0.31

e6/l

1.97

1768

5932

Symptoms and signs involving the urinary system

4595

11870

3.24

307.65

4.0

2.3

0.21

0.31

e6/l

6.92

4519

11527

Metabolic disorders

3982

12925

1.98

302.05

3.8

2.4

0.29

0.28

e6/l

0.10

3897

12527

Hypertension, essential

3144

8638

2.15

291.45

3.5

2.2

0.29

0.27

e6/l

0.25

3065

8334

Unknown and unspecified causes of morbidity

568

1096

6.05

288.32

4.0

2.4

0.25

0.29

e6/l

0.27

562

1058

Hyperplasia of prostate

1877

4140

2.76

287.60

3.3

2.7

0.19

0.35

e6/l

4.31

1849

4073

Covid-19 suspected case

1086

3371

3.49

285.97

3.0

2.5

0.20

0.25

e6/l

0.51

1051

3250

Type 2 diabetes, wide definition

3425

11399

2.04

281.82

3.4

2.6

0.35

0.27

e6/l

1.74

3366

11063

General symptoms and signs

4574

12585

1.87

281.73

3.2

2.4

0.28

e6/l

0.01

4455

12192

Retention of urine

1626

5460

2.69

262.20

4.4

2.3

0.24

0.32

e6/l

2.33

1603

5360

Hyperlipidaemia, other/unspecified

1842

7486

2.48

257.18

3.8

2.6

0.22

0.30

e6/l

2.31

1814

7332

General examination and investigation of persons without complaint and reported diagnosis

2893

7575

2.10

248.94

3.4

2.4

0.23

0.29

e6/l

1.66

2837

7344

Parasetamol

3280

8620

2.00

245.23

2.9

2.3

0.27

0.29

e6/l

0.16

3197

8342

Hypertensive diseases

3074

8857

2.03

244.63

3.6

2.2

0.27

e6/l

0.08

3001

8549

Hypertension

3073

8853

2.03

244.47

3.6

2.2

0.27

e6/l

0.08

3000

8545

Disorders of lipoprotein metabolism and other lipidaemias

3389

11356

1.94

243.58

3.6

2.4

0.27

0.29

e6/l

0.33

3328

11040

Symptoms and signs involving the digestive system and abdomen

4179

11716

1.84

242.33

2.9

2.6

0.27

0.29

e6/l

0.40

4081

11377

Abdominal and pelvic pain

4150

11714

1.83

238.08

2.8

2.6

0.27

0.29

e6/l

0.36

4060

11375

Anaemias

973

2002

3.39

226.38

4.5

1.8

0.33

0.20

e6/l

1.81

945

1920

Persons with potential health hazards related to family and personal history and certain conditions influencing health status

3750

14503

1.81

221.26

3.7

2.5

0.28

e6/l

0.04

3671

14055

Other diseases of intestines

4176

14120

1.76

220.29

2.9

2.6

0.28

e6/l

0.06

4065

13690

Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

3832

15920

1.78

214.64

3.9

2.5

0.28

e6/l

0.02

3752

15448

Hypertensive diseases (excluding secondary)

2063

5548

2.24

212.10

3.9

2.0

0.27

0.24

e6/l

0.47

2009

5339

Implicit Sepsis

2969

12551

1.91

209.94

3.8

2.5

0.35

0.27

e6/l

1.82

2910

12212

Covid-19 confirmed case

1303

5275

2.63

209.18

3.8

2.7

0.30

0.28

e6/l

0.19

1283

5131

Other special examinations and investigations of persons without complaint or reported diagnosis

2861

7604

1.96

202.26

3.1

2.4

0.27

0.29

e6/l

0.21

2784

7372

Other symptoms and signs involving the nervous and musculoskeletal systems

1776

8349

2.23

199.96

3.1

2.7

0.29

0.27

e6/l

0.23

1733

8116

Supplementary factors related to causes of morbidity and mortality classified elsewhere

1352

5783

2.47

191.93

3.6

2.6

0.27

0.28

e6/l

0.07

1340

5620

Diseases of male genital organs

2174

5357

2.13

189.90

3.2

2.6

0.23

0.33

e6/l

1.97

2137

5263

Fever of other and unknown origin

2145

10143

2.03

189.38

3.9

2.4

0.28

e6/l

0.05

2111

9865

Type of accident

1260

5293

2.52

186.44

3.6

2.6

0.25

0.28

e6/l

0.34

1249

5140

Pure hypercholesterolaemia

2852

10581

1.87

185.56

3.6

2.5

0.28

0.29

e6/l

0.06

2801

10291

Insulin medication

2425

11086

1.94

184.14

3.8

2.7

0.32

0.27

e6/l

0.88

2384

10789

Pain, not elsewhere classified

1142

4606

2.61

183.62

3.4

2.4

0.29

0.28

e6/l

0.14

1121

4465

Headache

2403

10716

1.93

181.41

3.0

2.3

0.22

0.28

e6/l

1.23

2338

10360

Transplanted organ and tissue status

543

1454

4.18

181.37

9.8

2.6

0.17

0.26

e6/l

0.91

537

1413

Abnormalities of breathing

3448

12056

1.74

175.37

3.0

2.6

0.30

0.29

e6/l

0.04

3340

11692

Additional codes for the location of defect, injury or illness

388

844

5.40

172.38

2.8

2.6

0.32

0.23

e6/l

0.42

382

815

Other functional intestinal disorders

1794

8522

2.09

170.24

3.6

2.7

0.24

0.30

e6/l

1.50

1754

8285

Condition for Implicit Sepsis (Organ dysfunction codes)

3205

13721

1.75

169.74

3.6

2.5

0.33

0.27

e6/l

1.56

3129

13334

Insulin, intermediate and long-acting

2247

11915

1.92

169.33

3.8

2.7

0.33

0.27

e6/l

1.09

2207

11638

Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified

1310

2686

2.51

168.38

2.8

1.8

0.23

0.34

e6/l

2.17

1276

2575

Secondary uncertain malignant neoplasm, excluding all cancers (controls excluding all cancers)

1681

7253

2.13

165.01

3.1

2.6

0.44

0.30

e6/l

2.67

1660

7062

Presence of other devices

1090

4607

2.52

159.78

2.9

2.8

0.28

0.31

e6/l

0.40

1073

4494

Familial hypercholesterolemia

810

2983

2.95

159.20

4.0

2.6

0.34

0.31

e6/l

0.18

794

2924

Symptoms and signs involving the nervous and musculoskeletal systems

2222

12258

1.88

156.79

3.1

2.7

0.29

0.28

e6/l

0.19

2168

11944

Pain in throat and chest

3197

11636

1.72

156.79

3.0

2.6

0.24

0.29

e6/l

1.13

3120

11289

Heart failure, not strict

2851

11452

1.77

156.52

4.4

2.5

0.34

0.26

e6/l

1.80

2803

11157

L04AD Calcineurin inhibitors

539

1592

3.73

155.05

10.5

2.6

0.17

0.26

e6/l

0.90

533

1548

Glucagon-like peptide-1 (GLP-1) analogues

2185

9859

1.90

153.00

3.3

2.8

0.35

0.28

e6/l

1.18

2162

9620

Glomerular diseases

868

3396

2.75

150.91

7.9

2.7

0.20

0.29

e6/l

2.17

857

3314

Dorsalgia

3804

12900

1.63

149.43

3.0

2.6

0.23

0.29

e6/l

2.95

3703

12536

Diabetes, insuline treatment (Kela reimbursement), excluding more controls

3540

13397

1.65

149.14

3.3

2.6

0.35

0.27

e6/l

2.07

3476

12977

Insulin, combination of fast acting with intermediate-acting or long-acting

2431

12848

1.80

148.90

3.8

2.7

0.32

0.27

e6/l

0.88

2390

12540

COPD/asthma/ILD related pneumonia or pneumonia derived septicaemia

3298

12608

1.68

148.46

3.5

2.5

0.34

0.27

e6/l

1.70

3221

12229

3298

12608

1.68

148.46

3.5

2.5

0.34

0.27

e6/l

1.70

3221

12229

Diverticular disease of intestine

2710

10498

1.77

146.87

2.9

2.7

0.22

0.29

e6/l

3.10

2656

10208

Diabetes, insulin treatment (Kela reimbursement)

3719

14327

1.63

146.75

3.3

2.6

0.35

0.27

e6/l

1.82

3653

13882

Pneumonia, organism unspecified

3319

14847

1.66

145.78

3.5

2.5

0.34

0.26

e6/l

1.79

3255

14427

Polyuria

932

3823

2.59

145.65

3.7

2.3

0.25

0.31

e6/l

0.59

914

3738

Other sleep disorders

578

1855

3.41

145.25

3.6

2.8

0.32

0.25

e6/l

0.35

568

1807

ILD medications: immunosuppressive drugs

2294

12527

1.81

144.09

4.7

2.3

0.19

0.28

e6/l

5.16

2240

12159

Dialysis, with operation codes

637

2184

3.19

143.13

9.7

2.6

0.16

0.28

e6/l

2.59

631

2136

Influenza and pneumonia

3796

15972

1.60

141.77

3.5

2.5

0.34

0.26

e6/l

2.13

3706

15498

Abnormal findings on examination of blood, without diagnosis

1905

9683

1.92

141.05

3.6

2.8

0.21

0.29

e6/l

2.12

1877

9487

Hydronephrosis

572

1858

3.37

140.99

6.1

2.4

0.33

0.26

e6/l

0.69

563

1811

Malaise and fatigue

1844

8199

1.94

140.09

3.5

2.5

0.31

0.29

e6/l

0.22

1811

7984

Cardiovascular diseases (excluding rheumatic etc)

2186

6937

1.86

138.84

3.5

2.0

0.26

0.23

e6/l

0.45

2122

6673

Septicaemia

1626

8113

2.01

138.72

4.4

2.6

0.40

0.25

e6/l

3.89

1603

7936

Explicit Sepsis

1694

8550

1.98

138.23

4.3

2.6

0.41

0.27

e6/l

3.42

1670

8356

ILD medications

4239

15269

1.55

136.43

3.8

2.4

0.24

0.29

e6/l

2.36

4131

14825

Other septicaemia

1480

7350

2.06

136.42

4.4

2.6

0.40

0.26

e6/l

3.39

1462

7193

Other disorders of fluid, electrolyte and acid-base balance

1189

5343

2.25

136.40

4.3

2.5

0.36

0.30

e6/l

0.58

1152

5210

Other soft tissue disorders, not elsewhere classified

3410

13233

1.63

136.20

3.1

2.6

0.24

0.30

e6/l

2.05

3310

12857

Symptoms and signs involving cognition, perception, emotional state and behaviour

3535

15793

1.61

136.20

3.0

2.6

0.26

0.29

e6/l

0.67

3447

15330

Symptoms and signs involving the circulatory and respiratory systems

3781

12106

1.60

134.07

2.9

2.6

0.24

0.29

e6/l

1.27

3672

11741

Endocrine, nutritional and metabolic diseases

2955

9040

1.70

133.61

3.1

2.3

0.28

0.25

e6/l

0.48

2879

8724

Disorders of gallbladder, biliary tract and pancreas

3622

15001

1.59

132.70

3.1

2.7

0.36

0.26

e6/l

2.71

3557

14533

L04AA Selective immunosuppressants

877

3662

2.54

131.64

7.2

2.4

0.13

0.27

e6/l

5.99

862

3551

Infections, IBD-co-morbidities

666

1694

3.01

131.06

4.5

2.2

0.22

0.31

e6/l

0.95

650

1643

First line medication for Crohn's disease

4136

14853

1.55

130.92

3.7

2.4

0.25

0.29

e6/l

1.12

4032

14412

Pneumonias (Asthma/COPD co-morbidities)

3570

15934

1.59

130.84

3.5

2.5

0.34

0.26

e6/l

1.93

3491

15463

Pneumonia (excl. viral and due to other infectious organisms not elsewhere classified)

3515

15877

1.59

130.49

3.5

2.5

0.34

0.26

e6/l

1.91

3438

15418

Diseases of oesophagus, stomach and duodenum

3890

15473

1.56

129.38

3.0

2.6

0.26

0.29

e6/l

0.62

3804

15014

Diabetes mellitus

3660

14095

1.58

129.27

3.2

2.6

0.34

0.27

e6/l

1.54

3582

13643

Cardiovascular diseases

2058

6162

1.86

128.68

3.2

2.0

0.25

0.24

e6/l

0.10

1988

5936

Autoimmune diseases excluding thyroid diseases

3883

14062

1.56

128.56

3.4

2.5

0.25

0.29

e6/l

1.31

3782

13658

malignant neoplasm of male genital organs, excluding all cancers (controls excluding all cancers)

1425

4296

2.13

128.54

3.7

2.6

0.19

0.29

e6/l

2.48

1405

4231

Nausea and vomiting

1018

4485

2.33

128.52

4.1

2.5

0.27

0.31

e6/l

0.48

1000

4352

Low back pain

2664

12440

1.69

127.97

2.9

2.6

0.24

0.29

e6/l

1.31

2584

12088

Nephropathy related operations

607

2158

3.07

127.88

9.7

2.7

0.15

0.28

e6/l

2.90

600

2113

Intracranial trauma

2080

8783

1.82

127.85

2.9

2.5

0.30

0.28

e6/l

0.28

2039

8518

All pneumoniae

3578

16000

1.58

127.78

3.5

2.5

0.33

0.26

e6/l

1.92

3499

15529

Diabetes, varying definitions

3639

14058

1.58

127.53

3.2

2.6

0.34

0.27

e6/l

1.51

3561

13607

ILD medications: prednisolone, methylprednisolone, prednisone

4041

15071

1.55

127.49

3.9

2.4

0.24

0.29

e6/l

1.53

3943

14631

Implicit bacterial Sepsis

1575

7620

1.98

127.09

4.3

2.7

0.40

0.28

e6/l

1.98

1549

7465

Constipation

3193

14494

1.62

126.90

3.3

2.7

0.22

0.30

e6/l

3.22

3109

14097

Bacterial Sepsis

1756

8531

1.90

126.43

4.2

2.6

0.40

0.28

e6/l

2.26

1726

8350

Oral corticosteroids

3912

15599

1.55

126.19

3.3

2.5

0.27

0.29

e6/l

0.41

3814

15149

Certain infectious and parasitic diseases

3683

11885

1.58

125.74

3.2

2.3

0.32

0.24

e6/l

2.17

3578

11508

Autoimmune diseases excluding thyroid diseases, strict definition

3787

13774

1.56

125.27

3.4

2.5

0.24

0.29

e6/l

1.47

3687

13373

Type 2 diabetes

3514

13455

1.58

124.54

3.2

2.6

0.35

0.27

e6/l

1.88

3440

13018

Leisure time condition

770

3118

2.63

124.00

3.4

2.7

0.31

0.28

e6/l

0.27

762

3035

Diabetes medication

3649

14509

1.56

121.77

3.2

2.6

0.34

0.27

e6/l

1.82

3572

14050

Episodal and paroxysmal disorders

4091

13950

1.53

121.49

2.9

2.7

0.28

e6/l

0.05

3977

13536

Aplastic and other anaemias

1758

9253

1.87

121.47

4.3

2.7

0.34

0.29

e6/l

0.67

1724

9053

Malignant neoplasm of prostate, excluding all cancers (controls excluding all cancers)

1393

4179

2.10

121.03

3.6

2.6

0.19

0.29

e6/l

2.54

1373

4118

Persons encountering health services in other circumstances

1364

6988

2.02

120.53

3.6

2.4

0.32

0.27

e6/l

0.47

1337

6795

Complications of surgical and medical care, not elsewhere classified

3502

16444

1.56

120.38

3.4

2.6

0.29

0.28

e6/l

0.18

3431

15954

Diarrhoea and gastroenteritis of presumed infectious origin

2524

14064

1.67

119.25

3.6

2.6

0.33

0.28

e6/l

0.75

2469

13672

Intestinal infectious diseases

3329

16917

1.56

117.31

3.4

2.6

0.30

0.28

e6/l

0.36

3249

16433

Secondary hypertension

391

1113

3.79

116.52

7.9

2.3

0.12

0.22

e6/l

1.98

386

1087

malignant neoplasm of male genital organs

1788

6286

1.89

116.51

3.6

3.0

0.20

0.30

e6/l

2.60

1764

6204

Abnormal spermatozoa

649

2524

2.85

116.39

2.9

3.2

0.19

0.29

e6/l

1.57

644

2487

Pain (limb, back, neck, head abdominally)

2731

8353

1.67

116.26

2.9

2.6

0.24

0.30

e6/l

1.33

2659

8127

Malignant neoplasm of bladder, excluding all cancers (controls excluding all cancers)

626

2376

2.86

115.88

6.3

2.6

0.47

0.32

e6/l

0.99

621

2333

Gastrointestinal diseases

2109

6025

1.79

114.55

2.8

2.3

0.30

0.27

e6/l

0.43

2038

5806

Insulin, fast-acting

1392

7332

1.97

114.06

4.4

2.7

0.29

0.27

e6/l

0.30

1366

7151

Other dorsopathies, not elsewhere classified

3707

12937

1.54

113.98

2.8

2.6

0.23

0.29

e6/l

2.77

3612

12571

Pain in limb

2796

12748

1.62

113.61

3.0

2.6

0.26

0.30

e6/l

1.06

2717

12383

Malignant neoplasm of prostate

1756

6176

1.88

112.17

3.6

3.0

0.20

0.30

e6/l

2.60

1732

6097

Concussion

1757

8573

1.82

111.95

2.8

2.5

0.28

e6/l

0.05

1719

8321

Implicit viral Sepsis

799

3447

2.45

111.76

4.6

2.7

0.27

0.28

e6/l

0.02

787

3363

Viral Sepsis

800

3457

2.45

111.48

4.6

2.7

0.27

0.28

e6/l

0.00

788

3372

Polyarthropathies

2477

10124

1.67

110.95

3.4

2.6

0.29

e6/l

0.04

2419

9841

Autoimmune diseases related-to ILD

2994

17112

1.57

110.09

3.4

2.6

0.27

0.28

e6/l

0.28

2909

16623

Glomerular disorders in diseases classified elsewhere

559

2060

2.95

110.03

8.1

2.7

0.23

0.32

e6/l

1.12

553

2012

Asthma, unspecified (mode), excluding more controls

1811

8101

1.80

109.64

3.2

2.3

0.28

e6/l

0.01

1759

7845

Malignant neoplasm, excluding all cancers (controls excluding all cancers)

3081

11784

1.58

107.60

3.1

2.5

0.30

0.27

e6/l

0.59

3021

11384

Malignant neoplasm, wide definition for exclusion, excluding all cancers (controls excluding all cancers)

3081

11785

1.58

107.53

3.1

2.5

0.30

0.27

e6/l

0.59

3021

11385

Malignant neoplasm, wide definition for exclusion

3081

11786

1.58

107.50

3.1

2.5

0.30

0.27

e6/l

0.59

3021

11386

Secondary malignant neoplasm of respiratory and digestive organs, excluding all cancers (controls excluding all cancers)

729

3081

2.52

107.31

3.2

2.6

0.53

0.30

e6/l

2.04

723

3008

Finngen Rheumatological endpoints

3467

13112

1.54

107.01

3.0

2.6

0.26

0.29

e6/l

0.51

3365

12727

Antihypertensive medication - note that there are other indications

2024

6407

1.76

106.96

3.2

2.1

0.26

e6/l

0.10

1949

6202

Inflammatory bowel disease treatment related agents

4098

16006

1.48

106.05

3.4

2.5

0.26

0.29

e6/l

0.77

3989

15543

Secondary and unspecified malignant neoplasm of lymph nodes, excluding all cancers (controls excluding all cancers)

638

2570

2.66

104.39

2.7

2.6

0.42

0.30

e6/l

1.14

628

2512

Abnormal serum enzyme levels

1270

6665

1.98

102.45

3.6

3.0

0.18

0.28

e6/l

2.53

1253

6558

Lower back pain or/and sciatica

3595

16972

1.50

101.94

2.8

2.7

0.25

0.28

e6/l

0.70

3498

16487

Other heart diseases

1540

5581

1.87

101.70

3.4

2.0

0.31

0.24

e6/l

1.16

1502

5372

Cholelithiasis, broad definition with cholecystitis

3083

13952

1.55

101.31

3.0

2.7

0.37

0.26

e6/l

2.63

3029

13519

Asthma, unspecified (mode)

1864

8685

1.75

101.30

3.3

2.4

0.29

0.28

e6/l

0.04

1812

8412

Autoimmune diseases

4022

14138

1.48

101.12

3.2

2.5

0.26

0.29

e6/l

0.44

3919

13730

Pain associated with micturition

477

1682

3.04

101.03

4.4

2.3

0.16

0.30

e6/l

2.77

466

1633

Other anaemias

1590

8740

1.82

101.02

4.0

2.7

0.36

0.29

e6/l

0.97

1559

8551

Insulin, fast-acting or short human

1400

7690

1.89

100.61

4.4

2.7

0.29

0.27

e6/l

0.22

1374

7507

Other and unspecified anaemias

1571

8666

1.82

99.56

4.0

2.7

0.36

0.29

e6/l

0.97

1540

8479

Neurological diseases

3143

10388

1.55

98.95

2.8

2.5

0.30

0.28

e6/l

0.27

3053

10080

Diseases of pulp and periapical tissues

1294

7005

1.91

97.43

3.4

2.6

0.19

0.30

e6/l

3.47

1271

6822

Medical observation and evaluation for suspected diseases and conditions

2395

7599

1.65

96.96

3.0

2.4

0.30

0.29

e6/l

0.18

2347

7368

Used for control exclusion in common control thyroid runs

3826

13329

1.48

96.85

3.2

2.5

0.26

0.29

e6/l

0.49

3730

12948

Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified (FINNGEN)

1489

5197

1.86

96.62

3.1

2.0

0.31

0.24

e6/l

0.76

1451

4993

COPD/asthma related infections

3691

12620

1.49

96.29

3.1

2.5

0.28

0.27

e6/l

0.13

3594

12241

COPD/asthma/ILD related infections

3691

12620

1.49

96.29

3.1

2.5

0.28

0.27

e6/l

0.13

3594

12241

Temporomandibular joint disorders

546

2116

2.69

95.09

2.5

2.4

0.27

0.28

e6/l

0.06

524

2033

Type 2 diabetes, definitions combined, including avohilmo

3238

12876

1.52

95.09

2.9

2.6

0.36

0.27

e6/l

2.04

3168

12460

Glomerulonephritis

467

1691

2.99

94.91

7.9

2.7

0.17

0.29

e6/l

1.78

460

1649

Type 2 diabetes, strict (exclude DM1)

3240

13026

1.51

94.20

2.9

2.6

0.36

0.27

e6/l

1.95

3173

12608

Hypothyroidism (congenital or acquired)

857

2212

2.28

94.00

3.1

1.8

0.21

0.22

e6/l

0.12

833

2117

Type 2 diabetes, definitions combined

3228

12973

1.51

93.82

2.9

2.6

0.36

0.27

e6/l

1.92

3161

12556

Neoplasms

2638

9075

1.59

93.05

2.9

2.3

0.28

e6/l

0.01

2565

8782

Obesity due to excess calories

1550

8973

1.78

92.94

3.1

2.6

0.36

0.24

e6/l

2.10

1526

8695

Dizziness and giddiness

2600

13778

1.57

92.79

3.0

2.7

0.23

0.29

e6/l

1.90

2532

13391

Other symptoms and signs involving the digestive system and abdomen

603

2486

2.55

92.78

3.2

2.4

0.22

0.30

e6/l

1.30

592

2397

Neurological diseases, wide definition

1069

2616

2.10

92.27

3.0

2.0

0.29

e6/l

0.01

1039

2529

Inflammatory diseases of prostate (prostatitis)

533

2091

2.72

91.91

3.4

2.7

0.20

0.28

e6/l

0.58

527

2064

Cholelithiasis

2932

13732

1.53

91.76

3.0

2.7

0.37

0.26

e6/l

2.60

2883

13304

Other (not insulin) diabetes medications

3295

13502

1.50

91.72

2.9

2.6

0.36

0.27

e6/l

2.10

3228

13074

Bleeding

2865

13881

1.53

91.53

3.5

2.7

0.34

0.28

e6/l

1.09

2814

13512

Postpartum care and examination

534

1260

2.83

91.45

2.6

2.3

0.25

0.21

e6/l

0.27

525

1191

Heart failure and antihypertensive medication

895

2794

2.20

91.13

4.1

2.3

0.40

0.29

e6/l

0.88

881

2722

Other heart diseases, wide

3095

12913

1.51

91.07

3.1

2.5

0.28

0.26

e6/l

0.37

3008

12515

Hypothyroidism and >3 levothyroxin purchases

845

2202

2.26

90.91

3.0

1.8

0.20

0.22

e6/l

0.12

823

2107

Hypothyroidism, levothyroxine purchases

845

2202

2.26

90.91

3.0

1.8

0.20

0.22

e6/l

0.12

823

2107

Cardiac arrhythmias

2009

8124

1.67

90.44

2.9

2.3

0.27

0.25

e6/l

0.22

1953

7819

Neuromuscular dysfunction of bladder

412

1437

3.10

89.63

4.6

2.4

0.28

0.37

e6/l

0.51

399

1400

Dyspnoea

3057

15901

1.50

89.36

3.2

2.7

0.31

0.28

e6/l

0.47

2977

15450

Opioids

3540

12808

1.48

89.06

3.1

2.5

0.28

0.27

e6/l

0.11

3442

12428

Malignant neoplasm

3044

12148

1.52

88.92

3.1

2.5

0.30

0.27

e6/l

0.55

2985

11747

Secondary malignant neoplasm of other and unspecified sites, excluding all cancers (controls excluding all cancers)

867

4253

2.14

88.20

3.4

2.6

0.38

0.28

e6/l

1.16

855

4157

Dorsopathies

3668

12998

1.46

88.15

2.8

2.6

0.24

0.29

e6/l

1.40

3567

12632

Injuries to the head

3758

17239

1.44

87.88

2.9

2.7

0.29

0.28

e6/l

0.21

3681

16728

Bronchitis

3671

16892

1.45

87.76

3.3

2.6

0.26

0.28

e6/l

0.36

3574

16407

Sleep disorders (combined)

3379

15340

1.47

86.78

2.9

2.7

0.27

e6/l

0.09

3293

14902

Asthma, excluding more controls

2560

8850

1.57

86.34

2.9

2.3

0.26

0.28

e6/l

0.30

2481

8572

Other nutritional deficiencies

2083

12934

1.61

86.15

3.0

2.6

0.37

0.26

e6/l

2.41

2036

12514

Continuous positive airway pressure

742

2957

2.26

85.16

3.5

2.5

0.24

0.23

e6/l

0.08

730

2878

Abnormalities of heart beat

1225

6731

1.86

85.09

2.9

2.6

0.26

0.31

e6/l

0.86

1196

6537

Syncope and collapse

1541

8045

1.74

84.96

3.1

2.5

0.26

0.30

e6/l

0.59

1502

7853

Hypertensive heart and/or renal disease

918

3548

2.08

84.37

4.0

2.5

0.31

e6/l

0.03

910

3478

Oxycodone

1351

7495

1.81

83.91

3.9

2.6

0.41

0.29

e6/l

2.26

1334

7335

3972

14966

1.42

82.91

3.1

2.6

0.26

0.28

e6/l

0.40

3868

14533

Complications of procedures, not elsewhere classified

2710

15828

1.51

82.70

3.3

2.6

0.28

0.27

e6/l

0.01

2648

15353

Any reimbursement code in KELA

1868

5656

1.68

82.61

2.9

1.9

0.28

0.23

e6/l

0.81

1797

5426

Benign neoplasms

2561

9529

1.55

82.16

3.0

2.4

0.24

0.28

e6/l

0.59

2487

9222

Any event in cancer register

3104

12644

1.48

81.72

3.2

2.5

0.30

0.27

e6/l

0.38

3038

12213

Other disorders of kidney and ureter

541

2266

2.56

81.67

6.5

2.8

0.22

0.29

e6/l

0.53

533

2210

Other systemic involvement of connective tissue (FG)

921

4710

2.02

80.96

3.2

2.6

0.19

0.30

e6/l

4.29

887

4564

Biguanides

3217

13764

1.47

80.73

2.8

2.7

0.36

0.27

e6/l

2.08

3155

13337

Factors influencing health status and contact with health services

1125

2953

1.95

80.23

2.8

2.2

0.26

0.31

e6/l

0.68

1092

2872

Acute renal failure

801

3959

2.13

79.97

4.7

2.7

0.57

0.29

e6/l

3.25

795

3881

Persons encountering health services for examination and investigation

2346

7605

1.57

79.05

3.0

2.4

0.27

0.29

e6/l

0.14

2281

7373

Asthma

2651

9485

1.53

78.80

2.9

2.4

0.26

0.28

e6/l

0.37

2570

9189

Systemic connective tissue disorders

1217

6907

1.82

78.70

3.6

2.7

0.20

0.29

e6/l

3.25

1177

6720

Benign neoplasm of colon, rectum, anus and anal canal

1796

7952

1.65

78.66

3.1

2.5

0.27

0.29

e6/l

0.20

1750

7715

Special screening examination for other diseases and disorders

361

1252

3.06

78.61

3.9

2.4

0.30

0.28

e6/l

0.14

352

1215

Oedema, not elsewhere classified

1046

5648

1.90

78.06

3.7

2.5

0.31

0.28

e6/l

0.23

1026

5501

Other/unspecified dorsalgia

1280

7356

1.78

77.32

3.3

2.6

0.30

0.29

e6/l

0.08

1244

7143

Urolithiasis

1226

7032

1.81

76.88

3.7

2.8

0.27

0.28

e6/l

0.08

1208

6885

Other symptoms and signs involving the circulatory and respiratory systems

305

983

3.37

76.21

4.0

2.5

0.22

0.27

e6/l

0.32

299

956

Presence of other functional implants

1964

8889

1.60

75.74

3.5

2.7

0.27

0.30

e6/l

0.64

1932

8670

Other disorders of ear

3097

14505

1.45

73.83

2.9

2.7

0.24

0.30

e6/l

1.94

3007

14107

Soft tissue disorders

3619

13462

1.42

73.70

2.9

2.6

0.24

0.30

e6/l

1.92

3517

13081

Tramadol

2675

11751

1.49

73.50

3.4

2.5

0.30

0.28

e6/l

0.36

2605

11411

Other disorders of teeth and supporting structures

794

4037

2.05

72.81

3.7

2.7

0.24

0.31

e6/l

0.94

785

3938

Symptoms and signs involving the skin and subcutaneous tissue

2240

14957

1.52

72.48

3.0

2.7

0.24

0.28

e6/l

0.95

2178

14532

Obesity

1936

12499

1.57

71.73

3.0

2.6

0.43

0.25

e6/l

3.22

1891

12101

Obesity and other hyperalimentation

1944

12556

1.57

71.64

3.0

2.6

0.43

0.25

e6/l

3.21

1898

12154

Hypo-osmolality and hyponatraemia

614

2849

2.25

71.49

4.1

2.5

0.34

0.32

e6/l

0.11

592

2783

Benign neoplasm: Colon

1575

7445

1.66

71.38

3.2

2.5

0.28

0.29

e6/l

0.05

1534

7237

Any gastric operation

2856

9886

1.47

70.74

2.9

2.3

0.32

0.25

e6/l

1.69

2779

9545

GASTRO-related operations

2856

9886

1.47

70.74

2.9

2.3

0.32

0.25

e6/l

1.69

2779

9545

Type 1 diabetes, wide definition, subgroup 1

724

3588

2.09

70.68

4.6

2.5

0.23

0.24

e6/l

0.10

709

3470

Other pulmonary diagnosis

2780

9562

1.48

70.58

2.9

2.4

0.27

0.28

e6/l

0.17

2705

9262

Type 1 diabetes

872

4616

1.95

70.11

4.7

2.6

0.24

0.25

e6/l

0.15

857

4477

Other neurological diseases

2434

13378

1.49

69.80

3.3

2.8

0.26

0.29

e6/l

0.58

2401

13029

Atrial fibrillation and flutter

1025

3642

1.89

69.73

3.2

2.1

0.33

0.25

e6/l

0.65

1006

3526

Diseases of the skin and subcutaneous tissue

3614

13088

1.40

69.60

3.1

2.5

0.24

0.29

e6/l

1.70

3517

12706

Nerve, nerve root and plexus disorders

3558

16238

1.40

69.31

2.9

2.7

0.26

0.29

e6/l

0.78

3457

15779

Congenital malformations of the urinary system

267

843

3.46

69.26

6.8

2.8

0.09

0.23

e6/l

4.96

258

818

Asthma (mode)

2552

9546

1.49

68.93

2.9

2.4

0.27

0.28

e6/l

0.21

2469

9248

Sleep apnoea

3004

14442

1.44

68.66

2.9

2.7

0.26

0.27

e6/l

0.30

2938

14034

Spondylopathies

2683

11270

1.47

68.66

2.8

2.7

0.28

0.30

e6/l

0.20

2616

10957

Gonarthrosis [arthrosis of knee](FG)

2625

10639

1.48

68.41

2.9

2.6

0.29

0.30

e6/l

0.18

2566

10342

Acute upper respiratory infections of multiple and unspecified sites

2424

12416

1.49

68.21

3.3

2.6

0.23

0.28

e6/l

0.98

2357

12044

Codeine

3219

12628

1.42

67.63

3.0

2.5

0.27

e6/l

0.01

3119

12251

Presence of cardiac and vascular implants and grafts

1603

7646

1.63

66.77

3.2

2.7

0.34

0.29

e6/l

0.54

1576

7494

Depression medications

901

2351

1.97

65.87

2.6

1.8

0.19

0.22

e6/l

0.51

858

2253

Excluding asthma or asthma-COPD overlap

2746

9562

1.46

65.43

2.9

2.4

0.27

0.28

e6/l

0.15

2670

9262

COPD differential diagnosis

2741

9549

1.46

65.14

2.9

2.4

0.27

0.28

e6/l

0.22

2664

9251

ILD differential diagnosis

2738

9546

1.46

64.79

2.9

2.4

0.27

0.28

e6/l

0.22

2661

9248

Asthma (only as main-diagnosis), excluding more controls

2210

8850

1.51

64.75

2.9

2.3

0.27

0.28

e6/l

0.07

2139

8572

Diseases of the ear and mastoid process

3950

14829

1.37

64.50

2.8

2.6

0.24

0.29

e6/l

1.67

3820

14416

Other diseases of anus and rectum

1003

5699

1.81

64.39

3.0

2.6

0.29

e6/l

0.03

984

5560

Gonarthrosis

2286

8900

1.50

63.88

2.8

2.6

0.31

0.30

e6/l

0.03

2232

8659

Other systemic involvement of connective tissue

932

5208

1.85

63.73

3.2

2.6

0.20

0.30

e6/l

2.90

897

5068

Carcinoma in situ of other and unspecified sites

197

546

4.13

63.72

8.5

2.6

0.16

0.31

e6/l

1.13

197

537

Sleep apnoea, including avohilmo

3155

14823

1.40

63.23

2.8

2.7

0.25

0.28

e6/l

0.51

3079

14407

Benign neoplasms

3380

13750

1.39

63.14

3.0

2.6

0.24

0.29

e6/l

1.39

3293

13370

Calculus of kidney and ureter

1095

6440

1.76

62.87

3.5

2.8

0.28

e6/l

0.04

1078

6306

Gastro-oesophageal reflux disease

2221

13516

1.48

62.84

3.0

2.7

0.24

0.28

e6/l

0.80

2167

13122

Intracranial injury

1907

12317

1.53

62.70

2.9

2.7

0.31

0.28

e6/l

0.39

1869

12001

Conductive and sensorineural hearing loss

2624

12825

1.44

61.86

2.9

2.8

0.26

0.30

e6/l

1.00

2556

12502

Cholecystectomy

2291

14052

1.47

61.62

2.9

2.7

0.36

0.27

e6/l

1.62

2252

13627

Arthrosis

2493

9518

1.47

61.26

2.8

2.6

0.29

0.30

e6/l

0.04

2422

9261

Diseases of arteries, arterioles and capillaries (FINNGEN)

786

2888

1.96

60.62

3.8

2.2

0.32

0.23

e6/l

0.87

772

2810

Irritable bowel syndrome

850

4686

1.87

60.37

2.7

2.5

0.18

0.29

e6/l

2.79

819

4526

Type 1 diabetes, wide definition

741

3912

1.95

60.23

4.6

2.5

0.23

0.25

e6/l

0.17

725

3788

Heart failure,strict

1754

8330

1.56

59.81

3.8

2.6

0.37

0.27

e6/l

2.04

1723

8182

Functional dyspepsia

882

4941

1.84

59.71

3.2

2.6

0.19

0.27

e6/l

1.72

859

4790

Paralytic ileus and intestinal obstruction

875

4891

1.85

59.68

3.5

2.7

0.49

0.31

e6/l

2.18

857

4768

Viral and other specified intestinal infections

653

3243

2.02

58.99

4.0

2.4

0.21

0.28

e6/l

0.99

635

3135

Erysipelas

1777

10807

1.53

58.91

3.5

2.6

0.33

0.25

e6/l

1.45

1736

10538

Disorders of lens

2255

9825

1.48

58.88

3.6

2.7

0.31

0.28

e6/l

0.33

2207

9572

STROKE

1831

8443

1.54

58.82

3.3

2.4

0.29

0.27

e6/l

0.20

1804

8169

Sensorineural hearing loss

2489

12305

1.44

58.62

2.9

2.8

0.25

0.31

e6/l

1.26

2425

12005

Other retinal disorders

2088

11525

1.49

58.52

3.6

2.8

0.30

0.29

e6/l

0.06

2042

11258

Dentinal caries

783

4240

1.90

58.25

3.9

2.6

0.38

0.30

e6/l

0.56

775

4143

Dentofacial anomalies [including malocclusion]

847

4660

1.85

58.23

2.9

2.4

0.28

e6/l

0.06

811

4507

Cerebrovascular diseases (FINNGEN)

953

3865

1.81

57.97

3.5

2.1

0.29

0.25

e6/l

0.31

932

3729

Dental caries

868

4832

1.84

57.95

4.0

2.6

0.36

0.29

e6/l

0.57

856

4724

Disorders of choroid and retina

2628

13696

1.42

57.75

3.5

2.7

0.28

0.29

e6/l

0.09

2566

13338

Migraine

1369

7335

1.62

57.45

2.6

2.4

0.21

0.27

e6/l

1.27

1321

7049

Heartburn

365

1496

2.57

57.27

3.2

2.5

0.18

0.29

e6/l

1.46

354

1444

Enlarged lymph nodes

528

2525

2.17

57.15

3.2

2.4

0.18

0.27

e6/l

2.13

516

2445

Asthma (only as main-diagnosis)

2265

9485

1.46

56.65

2.9

2.4

0.27

0.28

e6/l

0.14

2192

9189

Dysphagia

790

4357

1.87

56.38

3.3

2.6

0.25

0.29

e6/l

0.55

772

4248

Other arrhythmias

2026

10663

1.48

55.88

2.8

2.5

0.28

0.27

e6/l

0.09

1969

10333

Diseases of the digestive system

1532

10034

1.56

55.53

3.3

2.8

0.35

0.28

e6/l

1.00

1499

9805

Other medical care

1249

7643

1.64

55.24

3.5

2.5

0.44

0.28

e6/l

2.08

1229

7452

Hypertensive Heart Disease

749

3318

1.91

54.69

3.6

2.5

0.34

0.31

e6/l

0.23

743

3252

Other disorders of skin and subcutaneous tissue

2181

14089

1.44

54.07

3.7

2.7

0.30

0.29

e6/l

0.15

2128

13710

Other antidepressants

3538

13862

1.35

53.86

2.9

2.7

0.27

e6/l

0.00

3435

13499

Carcinoma in situ, bladder

175

503

3.96

53.67

8.4

2.6

0.15

0.32

e6/l

1.17

175

496

Excessive, frequent and irregular menstruation

1139

3800

1.70

53.66

2.7

2.3

0.22

0.34

e6/l

3.52

1099

3648

All influenza

828

4713

1.81

53.14

3.9

2.6

0.27

0.28

e6/l

0.14

809

4606

Sciatica+with lumbago

1547

9727

1.54

53.07

2.7

2.6

0.31

0.28

e6/l

0.28

1507

9439

Familial hypercholesterolemia, with ischemic heart disease

428

1971

2.33

52.33

4.1

2.9

0.24

0.31

e6/l

0.74

422

1938

Pain in joint

1713

7594

1.52

52.29

2.9

2.5

0.21

0.30

e6/l

2.66

1650

7385

Atrial fibrillation and flutter with reimbursement

822

2931

1.85

52.28

3.1

2.2

0.37

0.25

e6/l

0.76

808

2848

Coxarthrosis [arthrosis of hip](FG)

1811

8929

1.50

51.98

2.9

2.7

0.24

0.32

e6/l

1.56

1771

8697

Cystic kidney disease

166

470

3.94

51.64

7.0

2.7

0.05

0.22

e6/l

4.41

159

456

Use of hypnotics and sedatives

3494

15301

1.34

51.26

3.2

2.6

0.28

e6/l

0.04

3399

14872

ILD medications: azathioprine

488

2368

2.14

50.89

5.7

2.3

0.21

0.27

e6/l

0.73

480

2291

Nutritional anaemias

1568

10243

1.52

50.84

3.6

2.7

0.32

0.30

e6/l

0.18

1534

9991

Iron deficiency anaemia

1330

8556

1.58

50.60

3.6

2.7

0.33

0.29

e6/l

0.39

1301

8343

Other headache syndromes

1245

7960

1.60

50.53

2.8

2.5

0.18

0.28

e6/l

4.31

1201

7687

Tubulo-interstitial nephritis, not specified as acute or chronic

277

1065

2.77

50.02

4.8

2.2

0.30

e6/l

0.00

270

1033

Other intervertebral disc disorders

2670

11953

1.39

49.84

2.7

0.26

0.29

e6/l

0.54

2574

11617

Diseases of the eye and adnexa

2750

10053

1.39

49.77

3.0

2.4

0.22

0.28

e6/l

2.21

2657

9759

Inflammatory diseases of female pelvic organs

1658

8446

1.50

49.63

2.7

2.4

0.30

0.28

e6/l

0.14

1601

8090

Coxarthrosis

1689

7768

1.51

49.26

2.9

2.7

0.25

0.32

e6/l

1.36

1651

7580

Arthropathies

3011

11375

1.36

49.16

2.9

2.6

0.28

0.29

e6/l

0.14

2912

11056

Polycystic ovarian syndrome, consortium definition

1958

8207

1.46

48.84

2.7

2.4

0.24

0.30

e6/l

1.38

1891

7863

Disorders of thyroid, IBD co-morbidities

533

1928

2.07

48.71

3.1

2.0

0.18

0.31

e6/l

2.56

515

1862

Other or unspecified ileus, impaction or obstruction

629

3387

1.93

48.67

3.5

2.8

0.56

0.31

e6/l

2.20

615

3312

Obesity related asthma

1050

6522

1.65

48.62

3.3

2.7

0.29

0.27

e6/l

0.15

1024

6350

Other acute lower respiratory infections

1706

11216

1.48

48.26

3.6

2.7

0.31

0.28

e6/l

0.23

1668

10926

Gonarthrosis,primary

2912

13669

1.36

48.22

2.8

0.28

0.29

e6/l

0.22

2844

13301

Complications of medical and surgical care

2283

15730

1.40

48.04

3.3

2.7

0.30

0.27

e6/l

0.39

2233

15279

Psoriatic and enteropathic arthropathies

410

1911

2.24

47.76

2.5

2.4

0.31

0.27

e6/l

0.19

402

1856

Ovarian cyst

1035

3623

1.69

47.64

2.7

2.3

0.21

0.34

e6/l

3.83

1003

3477

Carcinoma in situ of other and unspecified sites

197

660

3.38

47.44

8.5

2.8

0.16

0.32

e6/l

2.23

197

651

Other and unspecified iron deficiency

1039

6482

1.65

47.23

3.6

2.7

0.31

0.29

e6/l

0.29

1016

6311

Asthma (diagnoses ohter than nonallergic)

2721

17359

1.36

47.17

3.1

2.7

0.28

e6/l

0.09

2645

16861

Azathioprine

488

2442

2.07

46.85

5.7

2.3

0.21

0.27

e6/l

0.68

480

2362

Osteopathies and chondropathies

1671

10940

1.48

46.81

3.5

2.6

0.26

0.28

e6/l

0.31

1631

10633

Combinations of oral blood glucose lowering drugs

932

5700

1.69

46.23

2.9

2.8

0.23

0.27

e6/l

0.68

919

5584

Hypokalaemia

383

1762

2.28

46.15

4.1

2.4

0.40

0.27

e6/l

0.95

372

1718

Codeine or tramadol medication

3749

16104

1.30

45.86

3.0

2.6

0.28

e6/l

0.06

3637

15664

Diseases of arteries, arterioles and capillaries

2174

11715

1.41

45.82

3.7

2.7

0.31

0.29

e6/l

0.24

2134

11457

Other bacterial intestinal infections

605

3283

1.91

45.81

3.8

2.7

0.26

0.31

e6/l

0.44

593

3202

Hypermobility syndrome

195

652

3.18

45.63

2.8

2.5

0.17

0.22

e6/l

0.45

188

619

Infections of the skin and subcutaneous tissue

1749

12197

1.45

45.53

3.2

2.7

0.25

0.27

e6/l

0.33

1713

11878

L04AX Other immunosuppressants

1643

11389

1.47

45.26

3.5

2.6

0.20

0.28

e6/l

4.05

1606

11059

Senile cataract

2036

8990

1.43

45.12

3.5

2.7

0.31

0.29

e6/l

0.21

1999

8771

Preparatory care for dialysis

200

696

3.16

44.48

11.3

3.0

0.14

0.25

e6/l

1.97

200

678

Second line medication for Crohn's disease

1678

11727

1.46

44.23

3.5

2.6

0.20

0.28

e6/l

4.35

1640

11392

Heart failure, strict

1899

9713

1.44

43.91

3.7

2.8

0.39

0.28

e6/l

2.28

1865

9547

All-cause Heart Failure

1878

9600

1.44

43.87

3.7

2.8

0.39

0.28

e6/l

2.28

1844

9436

Spondylosis

1665

9948

1.46

43.85

2.7

0.26

0.30

e6/l

0.77

1622

9685

Hernia

2944

15159

1.33

43.78

2.9

2.7

0.25

0.29

e6/l

0.82

2882

14709

Angina pectoris

1968

9504

1.43

43.36

3.2

2.7

0.26

0.29

e6/l

0.42

1939

9297

Diabetic retinopathy, excluding more controls

815

2686

1.77

43.09

4.2

2.4

0.31

0.30

e6/l

0.05

806

2619

Gout

949

5393

1.65

43.01

4.4

2.8

0.31

0.30

e6/l

0.05

938

5299

Asthma, hospital admission 2, infections

1794

12549

1.43

42.84

3.4

2.7

0.32

0.29

e6/l

0.34

1742

12202

Asthma-related infections

1794

12549

1.43

42.84

3.4

2.7

0.32

0.29

e6/l

0.34

1742

12202

Anxiety (asthma-related co-morbidities)

1712

9461

1.45

42.75

2.9

2.4

0.27

0.26

e6/l

0.17

1662

9140

GI-bleeding

1073

6916

1.59

42.62

3.5

2.9

0.39

0.30

e6/l

1.00

1055

6774

Benign neoplasm of colon, rectum, anus and anal canal

1947

12688

1.41

42.31

3.1

2.8

0.26

0.29

e6/l

0.41

1899

12392

Other symptoms and signs involving cognitive functions and awareness

1398

8939

1.50

41.98

3.4

2.8

0.26

0.31

e6/l

0.78

1368

8728

Artrosis, including avohilmo

2773

11461

1.35

41.96

2.7

0.27

0.29

e6/l

0.23

2697

11136

Other anxiety disorders

1263

7457

1.53

41.84

3.0

2.4

0.33

0.25

e6/l

0.88

1226

7193

Diseases of the musculoskeletal system and connective tissue

1761

6157

1.45

41.59

2.8

2.5

0.27

0.31

e6/l

0.59

1703

5983

Haemorrhage from respiratory passages

1113

6736

1.57

41.30

3.4

2.7

0.24

0.30

e6/l

1.15

1087

6597

All anxiety disorders

1736

9889

1.43

41.24

2.9

2.4

0.27

e6/l

0.04

1683

9559

Other diseases of the digestive system

1060

6867

1.58

41.20

3.5

2.9

0.40

0.30

e6/l

1.07

1043

6729

Hypothyroidism, drug reimbursement

404

1376

2.15

41.00

2.9

1.8

0.10

0.20

e6/l

2.38

394

1312

Sub-endpoint used in defining T1D endpoints

950

5897

1.62

40.98

4.6

2.7

0.24

0.29

e6/l

0.91

934

5738

Acute upper respiratory infections

3314

16131

1.30

40.92

3.0

2.6

0.23

0.29

e6/l

1.51

3220

15673

Agranulocytosis

374

1794

2.19

40.72

4.1

2.8

0.19

0.28

e6/l

1.28

368

1746

Other cataract

1378

7262

1.50

40.57

3.9

2.7

0.31

0.29

e6/l

0.29

1347

7096

Abnormal findings on diagnostic imaging and in function studies, without diagnosis

1988

13444

1.39

40.55

3.5

2.8

0.25

0.29

e6/l

0.86

1948

13112

Psoriatic arthropathies

349

1637

2.23

40.13

2.5

0.22

0.28

e6/l

0.48

341

1592

Carcinoma in situ, bladder

175

604

3.27

40.05

8.4

2.8

0.15

0.29

e6/l

1.74

175

596

Disorders of eyelid, lacrimal system and orbit

2625

15633

1.34

40.03

3.1

2.7

0.24

0.29

e6/l

1.35

2549

15194

Intestinal stricture

987

6336

1.60

40.01

3.4

2.8

0.51

0.29

e6/l

2.94

968

6190

1301

8767

1.50

39.86

3.4

2.7

0.30

0.28

e6/l

0.19

1259

8511

Other and unspecified dermatitis

1529

10724

1.45

39.71

3.0

2.7

0.23

0.29

e6/l

1.28

1487

10429

Pain and other conditions associated with female genital organs and menstrual cycle

523

2707

1.90

39.52

2.9

2.1

0.19

0.35

e6/l

3.23

506

2591

Other joint disorders

2802

11348

1.33

39.36

2.7

2.6

0.27

0.29

e6/l

0.33

2712

11029

Calculus of lower urinary tract

245

1006

2.64

39.35

5.0

2.9

0.23

0.26

e6/l

0.23

240

986

Dermatitis

1832

13273

1.40

39.35

3.0

2.7

0.26

0.28

e6/l

0.39

1780

12909

Follow-up examination after treatment for conditions other than malignant neoplasms

1312

5792

1.51

38.98

2.8

2.4

0.30

0.28

e6/l

0.23

1281

5601

Impacted teeth

501

2492

1.92

38.92

3.3

2.5

0.28

0.23

e6/l

0.28

490

2388

Injuries to the hip and thigh

1470

9388

1.46

38.91

3.0

2.8

0.33

0.29

e6/l

0.38

1443

9157

Acute bronchitis

1281

8570

1.49

38.34

3.6

2.7

0.33

0.29

e6/l

0.31

1252

8338

Injuries to the ankle and foot

1979

13244

1.38

38.33

2.9

2.6

0.23

0.27

e6/l

0.85

1913

12854

Vertebral, anorectal, cardiavascular, thracheoesophagial, renal and limb anomaly

489

2535

1.93

38.28

5.1

2.8

0.11

0.24

e6/l

5.32

476

2467

Chronic lower respiratory diseases

3840

16531

1.27

38.00

3.0

2.6

0.29

0.28

e6/l

0.13

3727

16068

Irregular menses

1212

6612

1.51

37.79

2.6

2.3

0.23

0.28

e6/l

0.81

1162

6311

Papulosquamous disorders

1183

7992

1.51

37.59

2.8

2.7

0.26

0.27

e6/l

0.09

1153

7773

Bacterial intestinal infections, IBD co-morbidities

595

3413

1.80

37.58

3.8

2.8

0.27

0.29

e6/l

0.20

583

3331

Anxiety disorders, excluding more controls

2468

12380

1.34

37.46

3.0

2.5

0.26

0.27

e6/l

0.08

2386

11999

Melanocytic naevi

804

4987

1.65

37.42

3.7

2.4

0.22

0.26

e6/l

0.57

775

4823

Sodium-glucose co-transporter 2 (SGLT2) inhibitors

732

4454

1.69

37.05

3.1

2.6

0.41

0.23

e6/l

1.53

722

4336

Preparation and fitting of bite rail to mouth

411

2110

2.02

36.86

2.4

2.6

0.28

0.25

e6/l

0.18

400

2036

Mouth breathing

1222

8346

1.49

36.59

2.8

0.26

e6/l

0.06

1185

8138

Malignant neoplasm of digestive organs, excluding all cancers (controls excluding all cancers)

1307

7017

1.48

36.39

3.0

2.6

0.52

0.29

e6/l

3.06

1294

6847

Benign neoplasm: Colon, unspecified

727

4423

1.68

36.16

3.3

2.6

0.30

e6/l

0.01

713

4326

Endometriosis

927

3495

1.61

35.87

2.7

2.3

0.25

0.34

e6/l

1.56

902

3354

Other viral diseases

824

5180

1.62

35.82

4.4

2.5

0.21

0.26

e6/l

0.58

807

5009

Any operation in hilmo

143

201

3.72

35.79

2.3

1.3

0.12

0.18

e6/l

0.48

135

196

Other disorders of bladder

414

2162

2.00

35.66

4.6

2.5

0.24

0.33

e6/l

0.84

409

2120

Inflammatory disease of uterus

400

2057

2.01

35.59

2.6

2.3

0.23

0.25

e6/l

0.20

382

1961

Unspecified mental disorder

1193

8158

1.49

35.44

2.9

2.6

0.31

0.27

e6/l

0.47

1165

7915

Menorrhagia

935

3284

1.60

35.33

2.8

2.3

0.22

0.34

e6/l

2.80

893

3158

Diseases of the respiratory system

2126

7891

1.37

35.31

2.8

2.4

0.27

0.29

e6/l

0.15

2059

7654

Injuries to the thorax

1370

9630

1.45

35.30

2.9

2.8

0.30

0.28

e6/l

0.26

1343

9407

Embedded and impacted teeth

664

3361

1.71

35.17

3.3

2.4

0.25

0.26

e6/l

0.08

646

3227

Female genital prolapse

794

2810

1.66

35.04

2.6

2.4

0.27

0.35

e6/l

0.97

766

2704

Reimbursement for rheumatic diseases

1688

12285

1.39

34.83

3.3

2.6

0.20

0.29

e6/l

4.02

1636

11923

Transient ischemic attack

1653

9933

1.41

34.81

3.2

2.8

0.27

0.30

e6/l

0.38

1635

9723

Primary_lymphoid and hematopoietic malignant neoplasms

710

4355

1.68

34.79

3.1

2.6

0.34

0.30

e6/l

0.31

701

4257

Neurotic, stress-related and somatoform disorders

2578

14119

1.31

34.75

3.0

2.5

0.26

0.28

e6/l

0.39

2495

13689

Mood disorders, excluding more controls

2920

13870

1.30

34.70

2.9

2.6

0.30

0.27

e6/l

0.61

2845

13462

Cough

1188

7815

1.48

34.66

3.0

2.6

0.27

0.29

e6/l

0.15

1152

7604

Diseases of peritoneum

353

1764

2.09

34.53

5.6

2.8

0.42

0.30

e6/l

0.71

347

1717

Anxiety disorders

2607

14277

1.31

34.35

3.0

2.5

0.26

0.28

e6/l

0.47

2523

13844

Elevated blood glucose level

281

1291

2.29

34.28

3.8

2.7

0.38

0.31

e6/l

0.30

276

1253

Myalgia

653

3933

1.70

34.23

3.1

2.5

0.26

0.30

e6/l

0.30

633

3819

Hypothyroidism, strict autoimmune

2275

11416

1.34

34.23

2.9

2.5

0.31

0.28

e6/l

0.27

2215

11061

Shoulder lesions

2437

11402

1.33

34.22

3.0

2.7

0.22

0.31

e6/l

3.97

2375

11094

Psychiatric diseases

3532

14104

1.27

33.98

3.0

2.6

0.28

0.27

e6/l

0.24

3435

13700

Other psoriatic arthropathies

332

1632

2.12

33.89

2.5

2.7

0.21

0.26

e6/l

0.51

325

1590

Psoriatic arthropathies, ICD10

340

1691

2.10

33.61

2.5

2.7

0.23

0.26

e6/l

0.28

332

1646

Other ulcerative colitis

206

837

2.60

33.35

3.3

2.7

0.41

0.20

e6/l

0.96

201

811

Sequelae of external causes of morbidity and mortality

764

4829

1.63

33.22

3.8

2.7

0.32

0.30

e6/l

0.15

751

4705

Redundant prepuce, phimosis and paraphimosis

552

3189

1.77

33.13

3.5

2.6

0.26

0.28

e6/l

0.11

542

3135

Any mental disorder

3601

14458

1.26

33.04

3.0

2.6

0.29

0.27

e6/l

0.38

3508

14043

Diseases of oral cavity, salivary glands and jaws

2994

12061

1.29

32.94

3.0

2.6

0.22

0.30

e6/l

3.54

2915

11724

Chronic periapical parodontitis

646

3927

1.69

32.90

3.5

2.6

0.19

0.30

e6/l

3.62

636

3829

TMD related operations

475

2652

1.85

32.82

2.5

2.6

0.26

0.25

e6/l

0.06

457

2564

Psoriasis

847

5493

1.58

32.80

2.9

2.7

0.27

0.28

e6/l

0.09

825

5350

Malignant neoplasm of bladder

306

1486

2.19

32.79

5.8

3.0

0.78

0.31

e6/l

2.07

301

1462

Migraine with aura

615

3685

1.70

32.73

2.5

2.4

0.23

0.24

e6/l

0.05

594

3541

Sequelae with surgical and medical care as external cause

613

3687

1.72

32.67

3.8

2.7

0.25

0.29

e6/l

0.41

604

3599

Depression

2822

15281

1.28

32.26

2.9

2.6

0.30

0.27

e6/l

0.48

2748

14816

Rash and other nonspecific skin eruption

319

1574

2.11

32.26

3.6

2.8

0.27

0.30

e6/l

0.09

313

1521

Biological medication for rheuma

438

2402

1.88

32.07

2.6

0.18

0.23

e6/l

0.85

422

2309

Other CVD

637

3895

1.69

31.95

3.8

2.9

0.34

0.30

e6/l

0.19

631

3816

Any mental disorder, or suicide (or attempt), or psychic disorders complicating pregnancy, partum or puerperum or nerve system disorders, excluding more controls

749

4745

1.61

31.85

2.9

2.4

0.24

e6/l

0.02

729

4576

Disorders of lacrimal system

1170

8151

1.46

31.72

3.1

2.6

0.20

0.30

e6/l

3.26

1136

7921

Benzodiazepine use

3076

17448

1.27

31.64

3.1

2.6

0.26

0.28

e6/l

0.55

2987

16953

Cytomegaloviral disease

111

335

3.68

31.51

8.6

2.5

0.31

0.18

e6/l

0.25

111

322

Benign neoplasm: Colon

1601

11543

1.38

31.45

3.2

2.8

0.28

0.29

e6/l

0.14

1560

11297

Disorders of other endocrine glands

1232

8536

1.44

31.32

4.1

2.6

0.28

e6/l

0.02

1207

8277

Hernia of abdominal wall, postoperative

578

3460

1.72

31.30

3.5

2.5

0.24

0.23

e6/l

0.11

567

3371

Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis

1596

9539

1.39

31.27

2.6

0.21

0.28

e6/l

1.89

1546

9195

Other abnormal uterine and vaginal bleeding

606

2575

1.72

31.26

2.6

2.4

0.29

0.36

e6/l

0.55

581

2478

Transport accidents

1388

8826

1.42

31.23

2.8

2.6

0.23

0.28

e6/l

0.99

1348

8584

Personality disorders, excluding more controls

694

4343

1.63

31.13

3.0

2.4

0.29

0.25

e6/l

0.32

680

4202

Abnormal findings on diagnostic imaging of other body structures

396

2132

1.93

31.05

3.5

2.7

0.14

0.30

e6/l

3.86

388

2073

Melanocytic naevi, other sites/unspecified

239

1070

2.34

30.97

4.4

2.5

0.25

0.23

e6/l

0.07

233

1034

Appendectomy

1844

13361

1.35

30.92

2.8

2.6

0.29

0.27

e6/l

0.27

1792

12946

Injuries to the neck

650

4021

1.66

30.79

2.9

2.6

0.25

0.28

e6/l

0.21

633

3884

Cytomegalovirus infection, IBD co-morbidity

109

334

3.63

30.29

8.7

2.6

0.31

0.19

e6/l

0.24

109

321

Other skin changes

533

3156

1.75

30.25

3.2

2.8

0.16

0.29

e6/l

3.03

518

3078

Injuries to the wrist and hand

2953

17078

1.27

30.18

2.8

2.7

0.30

0.28

e6/l

0.39

2868

16603

Cholecystitis

457

2595

1.82

30.07

3.2

2.9

0.29

e6/l

0.00

448

2533

Paroxysmal tachycardia

600

3070

1.69

30.01

3.0

2.1

0.19

0.22

e6/l

0.56

587

2974

Cellulitis

640

3977

1.65

29.88

3.5

2.7

0.27

0.28

e6/l

0.10

632

3880

Problems related to lifestyle

303

1506

2.08

29.85

3.4

2.5

0.37

0.24

e6/l

0.64

297

1460

Open wound of head

1556

11315

1.38

29.84

3.0

2.8

0.30

0.28

e6/l

0.28

1530

11056

Arthropathic psoriasis

348

1823

1.98

29.65

2.5

2.7

0.23

0.27

e6/l

0.33

339

1774

Kela-code for severe mental illness

1052

7275

1.47

29.65

2.9

2.6

0.34

0.27

e6/l

0.73

1029

7068

Polyarthrosis

580

3373

1.69

29.62

3.0

2.6

0.25

0.33

e6/l

1.07

565

3275

Non-ischemic cardiomyopathy

929

5132

1.52

29.55

3.6

2.7

0.40

0.29

e6/l

1.05

913

5032

Migraine without aura

494

2874

1.76

29.39

2.7

2.4

0.21

0.23

e6/l

0.16

471

2752

Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified

2966

15448

1.26

29.29

3.1

2.7

0.28

e6/l

0.01

2886

15016

Other disorders of lacrimal gland

944

6416

1.50

29.24

3.3

2.6

0.17

0.29

e6/l

5.30

911

6237

Disorders of vitreous body and globe

1437

10260

1.39

29.21

3.4

2.7

0.23

0.30

e6/l

1.46

1411

9994

Benign neoplasm: Skin of other and unspecified parts of face

332

1722

2.00

29.15

3.3

2.5

0.19

0.29

e6/l

1.60

327

1673

COPD (mode)

984

5328

1.50

29.02

3.5

2.6

0.35

0.28

e6/l

0.76

964

5230

L02BB Anti-androgens

367

1983

1.95

29.01

4.1

3.1

0.23

0.29

e6/l

0.74

360

1958

Other reaction to severe stress, and adjustment disorders

960

6551

1.49

28.90

3.5

2.4

0.25

e6/l

0.03

938

6309

Other diseases of biliary tract

283

1395

2.12

28.86

3.1

2.7

0.46

0.27

e6/l

1.00

274

1357

Cervicobrachial syndrome

623

3878

1.64

28.77

2.5

2.6

0.33

0.31

e6/l

0.09

605

3752

Asthma, including avohilmo

3647

17329

1.23

28.74

2.9

2.7

0.28

e6/l

0.05

3542

16846

Mood disorders

3073

16245

1.25

28.70

2.9

2.6

0.30

0.27

e6/l

0.43

2993

15757

Schizophrenia or delusion, excluding more controls

838

5530

1.53

28.67

3.0

2.5

0.36

0.25

e6/l

1.10

824

5363

Other diseases of blood and blood-forming organs, wide

648

4086

1.63

28.57

3.8

2.7

0.21

0.29

e6/l

1.79

637

3978

Disorders of vitreous body

1391

9956

1.39

28.52

3.4

2.7

0.23

0.30

e6/l

1.50

1365

9695

Fibromyalgia

249

1171

2.21

28.47

2.9

2.2

0.27

0.26

e6/l

0.01

237

1121

Viral pneumonia

389

2141

1.88

28.39

4.5

2.6

0.26

0.27

e6/l

0.06

384

2092

Other disorders of the genitourinary system

381

2089

1.89

28.24

3.5

2.7

0.29

0.32

e6/l

0.19

374

2031

Gout, FINNGEN

949

6519

1.49

28.16

4.4

2.9

0.31

0.30

e6/l

0.06

938

6420

Dislocation, sprain and strain of joints and ligaments at ankle and foot level

968

6641

1.48

28.12

2.6

2.5

0.23

0.26

e6/l

0.33

932

6433

Poisoning by drugs, medicaments and biological substances

642

4048

1.62

28.05

3.0

2.5

0.24

0.26

e6/l

0.09

625

3904

Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances

217

974

2.33

28.03

3.8

2.8

0.22

e6/l

0.02

212

941

Mood [affective] disorders

3058

16229

1.25

27.95

2.9

2.6

0.30

0.27

e6/l

0.48

2978

15741

Coxarthrosis, primary

1793

11834

1.34

27.88

2.9

0.24

0.30

e6/l

1.22

1755

11563

Other/unspecified cytomegaloviral diseases

287

3.75

27.84

8.9

2.3

0.34

0.13

e6/l

0.39

275

Migraine with aura and triptan purchases

390

2156

1.86

27.80

2.4

2.3

0.23

e6/l

0.03

377

2053

Rotator cuff syndrome

1866

10567

1.33

27.68

3.0

2.7

0.21

0.31

e6/l

4.87

1820

10295

Other and unspecified effects of external causes

740

4836

1.56

27.64

2.9

2.6

0.24

0.25

e6/l

0.14

715

4683

Paracetamol of NSAID medication

587

1768

1.70

27.56

2.8

2.7

0.27

0.36

e6/l

0.90

568

1728

Other abnormal findings in urine

256

3.96

27.54

5.8

2.9

0.33

0.29

e6/l

0.12

251

Superficial injury of hip and thigh

452

2625

1.78

27.44

3.1

2.8

0.33

0.30

e6/l

0.15

446

2565

Temporomandibular joint disorders, including avohilmo

1072

7542

1.44

27.24

2.5

0.23

0.25

e6/l

0.23

1025

7278

Nonorganic sleeping disorders, excluding more controls

491

2919

1.72

27.17

3.1

2.5

0.37

0.26

e6/l

0.68

470

2817

Disorders of the thyroid gland

2929

15427

1.25

27.12

2.9

2.7

0.28

e6/l

0.02

2857

14970

Dislocation, sprain and strain of joints and ligaments at neck level

418

2385

1.80

26.90

2.6

0.25

0.28

e6/l

0.14

405

2296

Fentanyl

350

1898

1.91

26.88

3.9

2.7

0.44

0.37

e6/l

0.38

343

1852

Demyelinating diseases of the central nervous system

257

1255

2.13

26.73

5.0

2.5

0.24

0.26

e6/l

0.07

252

1209

Lumbar disc prolapse

1817

11033

1.32

26.72

2.8

2.7

0.24

0.29

e6/l

0.80

1754

10720

Disorders of sclera, cornea, iris and ciliary body

1528

11453

1.35

26.63

3.0

2.7

0.22

0.27

e6/l

1.56

1494

11138

Chronic periodontitis

467

2764

1.74

26.59

4.0

2.7

0.24

0.33

e6/l

1.36

462

2695

Bipolar affective disorders

506

3049

1.70

26.59

2.6

2.5

0.24

0.26

e6/l

0.19

488

2932

Outcome of delivery

429

1493

1.82

26.48

2.5

2.2

0.22

0.20

e6/l

0.16

413

1415

Other specific joint derangements/joint disorders

2068

10752

1.30

26.45

2.8

2.5

0.21

0.29

e6/l

2.46

1994

10445

Peripheral artery disease

1404

8350

1.38

26.41

4.0

2.8

0.34

0.29

e6/l

0.57

1381

8202

Poisoning by medicine

579

3619

1.63

26.30

3.0

2.5

0.24

0.25

e6/l

0.08

566

3485

Certain disorders involving the immune mechanism

550

3404

1.66

26.22

4.7

2.6

0.19

0.28

e6/l

1.98

538

3302

Asthma-related pneumonia

1056

7475

1.44

26.18

3.9

2.8

0.37

0.30

e6/l

0.73

1033

7299

Venous thromboembolism

1603

11774

1.34

26.18

3.7

2.7

0.36

0.29

e6/l

0.77

1562

11499

Artificial joint operation, meniscal resection

2761

14782

1.26

26.09

2.8

0.28

0.29

e6/l

0.02

2703

14383

Insulin, fast-acting (human)

413

2369

1.79

26.09

5.4

2.4

0.19

0.27

e6/l

1.06

406

2291

Cutaneous abscess, furuncle and carbuncle

711

4672

1.55

26.01

3.3

2.6

0.30

0.26

e6/l

0.32

692

4539

Asthma-related pneumonia or sepsis

1057

7492

1.43

26.00

3.9

2.8

0.37

0.30

e6/l

0.73

1034

7314

Asthma, hospital admissions 3, pneumonia

1057

7492

1.43

26.00

3.9

2.8

0.37

0.30

e6/l

0.73

1034

7314

Congenital malformations, deformations and chromosomal abnormalities

1596

11561

1.34

25.90

3.4

2.5

0.19

0.27

e6/l

3.61

1540

11204

Noninflammatory disorders of female genital tract

1100

3871

1.45

25.82

2.7

2.3

0.23

0.34

e6/l

2.41

1054

3716

Thyroiditis, ILD-related definition

317

1684

1.94

25.82

3.2

2.5

0.17

0.28

e6/l

1.72

307

1620

Acute sinusitis

1403

9711

1.36

25.70

3.2

2.5

0.25

0.27

e6/l

0.21

1363

9405

Osteoporosis

715

4496

1.55

25.70

3.8

2.7

0.27

0.31

e6/l

0.75

704

4383

Other diseases of jaws

226

1070

2.21

25.63

3.5

2.6

0.20

0.34

e6/l

1.54

226

1039

Meniscus derangement

1696

8811

1.33

25.63

2.7

2.6

0.25

0.30

e6/l

0.66

1649

8575

Enterocolitis due to Clostridium difficile

349

1923

1.89

25.57

4.2

2.8

0.33

0.32

e6/l

0.04

344

1876

Acute appendicitis, no complications

1555

11721

1.34

25.52

2.6

0.19

0.27

e6/l

3.81

1515

11354

Ischaemic heart disease, wide definition

2296

11339

1.28

25.50

3.3

2.6

0.29

e6/l

0.01

2264

11038

Injuries to the abdomen, lower back, lumbar spine and pelvis

1122

8021

1.41

25.39

3.5

2.7

0.30

0.29

e6/l

0.18

1102

7807

Rheumatoid arthritis

928

5869

1.46

25.13

2.9

2.6

0.20

0.31

e6/l

4.86

905

5710

In situ neoplasms

963

6444

1.45

25.12

4.5

2.5

0.24

0.28

e6/l

0.48

952

6246

Statin medication

2065

9007

1.30

25.08

3.2

2.4

0.28

0.27

e6/l

0.10

1988

8726

Other complications of surgical and medical care, not elsewhere classified

292

1530

1.98

24.95

3.3

2.6

0.29

0.30

e6/l

0.05

287

1478

Recurrent or chronic depression

1112

5741

1.42

24.86

2.8

2.5

0.35

0.27

e6/l

0.77

1080

5558

Obesity, other/unspecified

881

6106

1.47

24.65

2.8

2.5

0.50

0.25

e6/l

2.43

847

5903

Acute appendicitis

1995

14760

1.29

24.62

2.7

0.22

0.28

e6/l

2.36

1941

14322

Melanocytic naevi

804

5483

1.50

24.58

3.7

2.6

0.22

0.27

e6/l

0.80

775

5315

Fall on same level

3546

16405

1.22

24.55

3.0

2.6

0.29

0.27

e6/l

0.31

3447

15934

Misadventures to patients during surgical and medical care

427

2522

1.75

24.55

3.5

2.7

0.28

0.29

e6/l

0.06

417

2447

Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

1757

13537

1.31

24.48

3.4

2.7

0.31

0.28

e6/l

0.32

1724

13173

Disorders of synovium and tendon

1482

10064

1.34

24.44

2.8

2.6

0.25

0.30

e6/l

0.67

1434

9762

Pain in thoracic spine

410

2393

1.76

24.39

2.9

2.5

0.20

0.32

e6/l

1.22

399

2310

Colorectal cancer, excluding all cancers (controls excluding all cancers)

790

5200

1.50

24.39

3.2

2.6

0.38

0.31

e6/l

0.72

781

5084

Other degenerative diseases of the nervous system

817

4211

1.50

24.38

3.9

2.7

0.41

0.30

e6/l

0.68

803

4119

Acute pharyngitis

378

2142

1.79

24.22

2.9

2.4

0.19

0.25

e6/l

0.56

372

2065

Sulfonylureas

1132

6540

1.41

24.20

3.3

2.9

0.32

0.29

e6/l

0.23

1116

6423

Injuries to the shoulder and upper arm

2447

16489

1.26

24.16

2.9

2.7

0.24

0.29

e6/l

1.62

2397

16049

Dental operations

2157

8687

1.29

24.12

3.0

2.6

0.26

0.32

e6/l

1.79

2105

8436

Disorders of skin appendages

1287

9540

1.37

24.10

3.0

2.6

0.22

0.27

e6/l

1.09

1246

9260

Tumor necrosis factor alpha inhibitors

372

2121

1.80

24.06

2.6

2.5

0.18

0.24

e6/l

0.88

360

2046

Ventral hernia

709

4742

1.53

24.03

3.3

2.7

0.24

0.29

e6/l

0.78

696

4618

Dermatitis and eczema

3268

17689

1.22

24.01

2.9

2.7

0.25

0.28

e6/l

0.86

3171

17198

Noninfective enteritis and colitis

1307

9713

1.36

23.99

3.1

2.7

0.31

0.27

e6/l

0.41

1266

9450

Other noninflammatory disorders of uterus, except cervix

554

2359

1.64

23.85

2.9

2.5

0.41

0.37

e6/l

0.18

539

2275

Ischemic heart diseases

2306

11496

1.27

23.83

3.2

2.6

0.29

e6/l

0.06

2274

11188

Hernia of abdominal wall

1318

9841

1.36

23.79

3.2

2.8

0.24

0.27

e6/l

0.71

1294

9613

Other disorders of penis

272

1414

1.99

23.77

3.9

2.7

0.27

0.26

e6/l

0.05

265

1392

Melanocytic naevi, other sites/unspecified

239

1190

2.09

23.74

4.4

2.8

0.25

0.30

e6/l

0.23

233

1152

Injury, poisoning and certain other consequences of external causes

1720

6573

1.32

23.68

2.8

2.6

0.29

0.28

e6/l

0.09

1671

6353

Symptoms and signs concerning food and fluid intake

292

1555

1.94

23.61

3.6

2.5

0.34

0.27

e6/l

0.34

287

1513

Cyst of kidney

237

1184

2.11

23.58

3.9

2.8

0.29

0.30

e6/l

0.01

232

1159

Other viral diseases, not elsewhere classified

493

3043

1.65

23.43

4.4

2.6

0.18

0.28

e6/l

1.85

484

2941

Drug-induced neutropenia

225

1105

2.13

23.33

3.7

2.8

0.20

0.29

e6/l

0.98

219

1075

Hard cardiovascular diseases

2305

11813

1.27

23.29

3.4

2.6

0.29

0.28

e6/l

0.05

2266

11511

Valvular heart disease excluding rheumatic fever

1367

7471

1.36

23.27

3.3

2.6

0.26

0.28

e6/l

0.23

1332

7310

Other hearing loss

829

5653

1.47

23.25

3.4

2.9

0.28

0.33

e6/l

0.63

808

5536

Vocal cord dysfunction

353

1852

1.81

23.19

3.0

2.2

0.34

0.27

e6/l

0.29

345

1792

Soft tissue disorders related to use, overuse and pressure

750

5113

1.50

23.03

2.9

2.6

0.19

0.31

e6/l

3.81

727

4990

Convulsions, not elsewhere classified

619

3998

1.56

23.03

3.4

2.4

0.38

0.27

e6/l

0.78

604

3887

Melanocytic naevi of trunk

314

1727

1.87

23.01

4.1

2.5

0.24

0.25

e6/l

0.06

305

1670

Drugs, medicaments and biological substances causing adverse effects in therapeutic use

266

1390

1.99

22.99

3.5

2.8

0.24

0.28

e6/l

0.24

261

1345

Specific personality disorders

608

3969

1.56

22.92

3.0

2.5

0.29

0.25

e6/l

0.23

594

3819

Hypothyroidism, other/unspecified

2666

14307

1.24

22.91

2.9

2.7

0.29

0.28

e6/l

0.22

2599

13874

Gonarthrosis, primary, with knee surgery

1650

10408

1.31

22.85

2.8

0.34

0.30

e6/l

0.41

1618

10170

Non-rheumatic valve diseases

1359

7436

1.35

22.81

3.3

2.6

0.26

0.28

e6/l

0.21

1324

7275

Behavioural and emotional disorders with onset usually occurring in childhood and adolescence

454

2510

1.68

22.76

2.7

2.5

0.25

0.22

e6/l

0.27

441

2405

Diseases of inner ear

1527

11472

1.32

22.63

2.8

0.20

0.29

e6/l

3.42

1478

11186

Other disorders of bone

541

3454

1.60

22.62

3.3

2.5

0.16

0.26

e6/l

2.20

523

3343

Carpal tunnel syndrome

1675

11726

1.31

22.58

2.8

2.6

0.25

0.28

e6/l

0.77

1627

11365

Selective serotonin reuptake inhibitors

3197

13901

1.22

22.57

2.7

0.31

0.28

e6/l

0.51

3104

13537

Personality disorders

694

4673

1.51

22.56

3.0

2.5

0.29

0.25

e6/l

0.32

680

4500

Diseases of appendix

2136

15552

1.26

22.47

2.7

0.22

0.28

e6/l

2.57

2080

15099

Benign neoplasm of other and unspecified endocrine glands

338

1916

1.82

22.45

3.4

2.5

0.22

0.28

e6/l

0.51

332

1859

Viral infections characterized by skin and mucous membrane lesions

1140

8391

1.38

22.44

3.8

2.7

0.27

0.28

e6/l

0.08

1112

8152

Stroke, excluding SAH

1795

10419

1.30

22.41

3.4

2.8

0.27

0.30

e6/l

0.39

1759

10201

Missing teeth due to accident, extraction or parodontitis

352

2025

1.80

22.33

3.3

2.7

0.23

0.30

e6/l

0.58

347

1975

Cervical disc disorders

1026

7442

1.40

22.26

3.0

2.7

0.33

0.30

e6/l

0.27

991

7254

Appendicitis, broad definition

2115

15453

1.26

22.25

2.7

0.22

0.28

e6/l

2.49

2059

15001

Other disorders of glucose regulation and pancreatic internal secretion

259

1357

1.98

22.23

4.5

2.8

0.29

0.25

e6/l

0.27

252

1319

Migraine without aura and triptan purchases

395

2341

1.72

22.19

2.5

2.3

0.23

0.24

e6/l

0.07

378

2231

Unspecified lump in breast

409

2456

1.71

22.02

2.6

2.4

0.21

0.30

e6/l

1.29

396

2366

malignant neoplasm of female genital organs, excluding all cancers (controls excluding all cancers)

464

2827

1.65

21.96

2.8

2.4

0.22

0.31

e6/l

1.70

449

2725

Epilepsy

866

6106

1.44

21.80

3.0

2.7

0.44

0.28

e6/l

1.17

845

5952

Disorders of vestibular function (Vertigo)

1292

9678

1.35

21.78

2.8

2.7

0.20

0.30

e6/l

3.22

1254

9432

Postmenopausal atrophic vaginitis

616

2411

1.57

21.75

2.7

2.4

0.22

0.37

e6/l

2.14

592

2321

Disorders of adult personality and behaviour

728

4986

1.48

21.74

3.0

2.5

0.28

0.24

e6/l

0.24

712

4805

Asthma, hospital admissions , main diagnosis only

2375

17255

1.24

21.71

2.9

2.7

0.27

0.28

e6/l

0.12

2301

16770

Rheumatism, unspecified

378

2232

1.74

21.67

3.2

2.4

0.19

0.30

e6/l

2.21

368

2157

Mental disorders, not otherwise specified

222

1110

2.07

21.67

3.5

2.6

0.17

0.22

e6/l

0.55

216

1074

Hyperkinetic disorders, excluding more controls

230

1128

2.03

21.66

2.3

2.2

0.18

0.21

e6/l

0.32

224

1084

Primary_lymphoid and hematopoietic malignant neoplasms

710

4856

1.50

21.64

3.1

2.9

0.34

0.29

e6/l

0.51

701

4757

Superficial injury of wrist and hand

509

3239

1.60

21.57

3.0

2.6

0.21

0.27

e6/l

0.65

492

3131

Failure and rejection of transplanted organs and tissues

197

3.94

21.56

12.5

2.4

0.44

0.10

e6/l

0.47

192

Panic disorder

373

2196

1.74

21.49

2.4

0.34

0.24

e6/l

0.52

364

2101

Disorders of breast

1178

8119

1.36

21.49

2.4

0.23

0.30

e6/l

1.78

1136

7776

DVT of lower extremities and pulmonary embolism

1203

8971

1.36

21.48

3.8

2.8

0.39

0.29

e6/l

0.97

1171

8771

Any mental disorder, or suicide (or attempt), or psychic disorders complicating pregnancy, partum or puerperium or nerve system disorders

749

5174

1.47

21.40

2.9

2.5

0.24

0.26

e6/l

0.19

729

4986

Sleep disorders

562

3666

1.56

21.37

3.3

2.6

0.37

0.26

e6/l

0.80

540

3540

Fracture of femur

787

5012

1.46

21.29

3.2

2.9

0.39

0.31

e6/l

0.52

775

4903

Mixed connective tissue disease

199

966

2.15

21.28

3.7

2.7

0.17

0.28

e6/l

1.14

192

930

Other arthrosis

1514

8325

1.32

21.20

2.8

2.6

0.20

0.30

e6/l

4.69

1465

8108

Lung transplant status

124

5.03

21.19

9.9

2.6

0.23

0.13

e6/l

0.44

119

Lung transplantation

124

5.03

21.18

9.9

2.6

0.23

0.13

e6/l

0.44

119

Benign neoplasm: Rectum, anus and anal canal

538

3490

1.58

21.13

2.8

2.6

0.18

0.29

e6/l

2.83

524

3414

Coxibs

938

3539

1.43

21.00

2.7

3.0

0.23

0.33

e6/l

1.97

916

3479

Falls/tendency to fall

3444

14437

1.20

20.92

2.9

2.6

0.27

e6/l

0.07

3349

14010

Nonorganic sleeping disorders

491

3126

1.60

20.82

3.1

2.6

0.37

0.27

e6/l

0.58

470

3016

Spinal stenosis

1492

9015

1.31

20.79

2.9

2.8

0.31

e6/l

0.02

1465

8794

Other arthritis (FG)

834

5916

1.43

20.68

3.3

2.6

0.23

0.28

e6/l

0.60

809

5751

Hypothyreosis and Thyroxine purchase for inclusion criteria

2726

14826

1.22

20.58

2.9

2.7

0.29

0.27

e6/l

0.26

2658

14368

Other diseases of hard tissues of teeth

1805

10626

1.28

20.53

3.0

2.5

0.20

0.29

e6/l

3.39

1764

10325

Schizophrenia, schizotypal and delusional disorders

843

6000

1.43

20.47

3.0

2.6

0.36

0.26

e6/l

1.03

829

5819

Schizophrenia or delusion

838

5959

1.43

20.46

3.0

2.6

0.36

0.27

e6/l

0.91

824

5779

Localized swelling, mass and lump of skin and subcutaneous tissue

868

6216

1.42

20.45

2.9

2.7

0.26

0.27

e6/l

0.10

841

6054

Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

1619

12686

1.29

20.42

3.3

2.7

0.29

0.28

e6/l

0.11

1591

12350

Other blood glucose lowering drugs, excl. Insulins

496

3187

1.60

20.40

3.1

2.8

0.35

0.29

e6/l

0.34

490

3118

Other specified/unspecified systemic involvement of connective tissue

178

842

2.21

20.38

3.5

2.6

0.14

0.30

e6/l

2.02

171

808

Degeneration of macula and posterior pole

1362

8599

1.33

20.25

3.1

2.9

0.32

e6/l

0.04

1334

8432

Haemorrhoids and perianal venous thrombosis

814

5771

1.43

20.22

3.0

2.7

0.27

0.31

e6/l

0.26

794

5632

L04AC Interleukin inhibitors

150

665

2.36

20.15

2.7

0.17

0.19

e6/l

0.16

141

639

Benign neoplasm: Skin of other and unspecified parts of face

332

1937

1.77

20.12

3.3

2.8

0.19

0.30

e6/l

1.84

327

1884

Primary gonarthrosis, bilateral

1452

9829

1.31

20.07

2.9

2.8

0.30

e6/l

0.03

1425

9586

Non-selective monoamine reuptake inhibitors

1097

7926

1.36

20.07

3.0

2.6

0.29

e6/l

0.05

1073

7715

Behavioural syndromes associated with physiological disturbances and physical factors

815

5783

1.43

20.06

3.2

2.5

0.34

0.27

e6/l

0.56

785

5591

Other and unspecified drugs and medicaments

245

1306

1.95

20.04

3.7

2.8

0.24

0.30

e6/l

0.33

240

1269

Conjunctivitis (acute, non atopic)

731

5081

1.46

19.94

3.1

2.6

0.17

0.28

e6/l

3.72

716

4928

Accidents

2675

11004

1.23

19.90

2.8

2.6

0.27

0.29

e6/l

0.23

2594

10690

Purpura and other haemorrhagic conditions

381

2312

1.70

19.86

4.1

2.8

0.33

0.27

e6/l

0.33

370

2253

Other external causes of accidental injury

2674

11004

1.23

19.82

2.8

2.6

0.27

0.29

e6/l

0.21

2594

10690

Benign neoplasm: Colon, unspecified

727

5086

1.46

19.77

3.3

2.9

0.30

e6/l

0.04

713

4986

Gastroduodenal ulcer

792

5609

1.44

19.69

3.2

2.9

0.38

0.30

e6/l

0.67

780

5495

Gout, idiopatic and unspecified

760

5367

1.45

19.69

4.3

2.9

0.28

0.30

e6/l

0.15

749

5280

Diseases of pulp and periapical tissues, including avohilmo

3368

14713

1.20

19.65

2.8

2.6

0.23

0.29

e6/l

2.52

3278

14308

Sicca syndrome [Sjögren]

244

1309

1.93

19.55

3.3

2.6

0.16

0.32

e6/l

2.36

230

1265

Cervicalgia

553

3669

1.54

19.50

2.9

2.5

0.23

0.32

e6/l

1.07

537

3558

External causes of morbidity and mortality

2146

8646

1.25

19.48

2.8

2.6

0.27

0.28

e6/l

0.08

2078

8392

Dental pulpitis 4

3369

14733

1.20

19.41

2.8

2.6

0.23

0.29

e6/l

2.47

3279

14327

Benign neoplasm: Rectum

475

3059

1.59

19.36

2.8

2.5

0.16

0.29

e6/l

3.77

462

2993

Dental pulpitis 1

3368

14740

1.20

19.28

2.8

2.6

0.23

0.29

e6/l

2.46

3278

14334

Acute pancreatitis

555

3698

1.53

19.28

3.3

2.9

0.40

0.27

e6/l

0.90

546

3609

Adalimumab

233

1236

1.94

19.23

2.4

2.5

0.18

0.21

e6/l

0.24

222

1191

Disorder of lipoprotein metabolism, unspecified

396

2449

1.66

19.19

3.4

2.6

0.34

0.29

e6/l

0.24

387

2406

Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care

233

1241

1.95

19.17

3.4

2.8

0.17

0.31

e6/l

1.77

228

1204

Hypoglycaemia, other or unspecified

207

1059

2.03

19.16

3.9

2.8

0.23

0.25

e6/l

0.10

200

1030

Psoriasis vulgaris

518

3406

1.56

19.16

3.1

2.7

0.27

0.28

e6/l

0.08

506

3313

Non-Hodgkin lymphoma, all, excluding all cancers (controls excluding all cancers)

375

2291

1.68

19.08

3.1

2.5

0.38

0.29

e6/l

0.55

369

2241

Zoster [herpes zoster]

498

3253

1.57

19.04

4.2

2.8

0.33

0.29

e6/l

0.15

489

3181

Viral warts

268

1491

1.85

19.04

4.2

2.7

0.19

0.25

e6/l

0.58

262

1453

Crohn disease

343

2045

1.72

19.04

3.0

2.6

0.31

0.27

e6/l

0.27

335

1986

Otitis externa

586

3959

1.51

18.97

2.8

2.7

0.31

0.29

e6/l

0.15

568

3850

Nosocomial condition (hospital)

5.59

18.96

5.6

3.2

0.18

0.09

e6/l

0.68

Fracture of rib(s), sternum and thoracic spine

846

6119

1.41

18.91

2.9

0.29

e6/l

0.01

833

5992

Donors of organs and tissues

160

3.97

18.88

3.0

2.0

0.05

0.18

e6/l

1.48

152

Insomnia

406

2532

1.64

18.86

3.4

2.6

0.37

0.27

e6/l

0.60

388

2445

Examination and observation for other reasons

1571

7462

1.29

18.83

2.5

2.4

0.31

0.28

e6/l

0.38

1493

7234

Ischaemic Stroke, excluding all haemorrhages

1671

10005

1.28

18.82

3.5

2.8

0.29

0.30

e6/l

0.05

1639

9806

Unspecified acute lower respiratory infection

419

2638

1.63

18.78

3.9

2.7

0.23

0.28

e6/l

0.57

409

2565

Other and unspecified disorders of vitreous body

1086

8131

1.35

18.72

2.8

2.7

0.20

0.31

e6/l

4.13

1062

7905

Other diseases of oesophagus

301

1745

1.78

18.70

3.7

2.8

0.28

0.29

e6/l

0.06

294

1705

325

1918

1.73

18.69

3.6

2.3

0.26

e6/l

0.01

316

1851

Superficial injury of abdomen, lower back and pelvis

407

2550

1.63

18.59

3.3

2.6

0.22

0.29

e6/l

1.03

402

2474

Stroke, including SAH

1849

10977

1.26

18.56

3.4

2.8

0.30

0.29

e6/l

0.10

1813

10728

Asthma/COPD (KELA code 203)

2801

16489

1.21

18.56

3.0

2.6

0.28

e6/l

0.00

2721

16027

Coagulation defects, purpura and other haemorrhagic conditions

516

3416

1.54

18.49

4.2

2.7

0.26

0.29

e6/l

0.23

499

3325

Deforming dorsopathies

723

5105

1.44

18.46

2.9

2.6

0.35

0.30

e6/l

0.25

696

4948

Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances

411

2583

1.62

18.45

2.8

2.5

0.24

0.27

e6/l

0.17

400

2480

Other enthesopathies

791

5675

1.42

18.42

2.6

0.21

0.32

e6/l

3.08

770

5512

Colectomy operation

494

3251

1.56

18.34

3.2

2.9

0.34

0.29

e6/l

0.26

482

3184

Superficial injury of thorax

417

2641

1.62

18.27

3.2

2.7

0.28

e6/l

0.02

402

2574

Personal history of other diseases and conditions

266

1492

1.82

18.01

3.5

2.3

0.30

0.23

e6/l

0.33

258

1431

Other benign neoplasms of skin

952

6927

1.37

18.01

2.9

2.5

0.23

0.29

e6/l

1.50

935

6722

Conduction disorders

846

5107

1.40

17.97

3.1

2.7

0.38

0.28

e6/l

1.06

827

4997

SLE, ICD10

116

485

2.53

17.96

4.5

2.7

0.15

0.20

e6/l

0.39

111

468

SLE, strict definition

116

485

2.53

17.96

4.5

2.7

0.15

0.20

e6/l

0.39

111

468

Malignant neoplasm of colon, excluding all cancers (controls excluding all cancers)

523

3499

1.53

17.88

3.1

2.6

0.33

0.31

e6/l

0.17

517

3421

Seropositive rheumatoid arthritis

684

4801

1.45

17.87

2.9

2.6

0.18

0.30

e6/l

4.34

668

4662

Emotionally unstable personality disorder

300

1754

1.75

17.87

3.3

2.3

0.24

0.22

e6/l

0.10

294

1675

Depression or dysthymia

2151

9803

1.24

17.83

2.8

2.6

0.27

0.28

e6/l

0.08

2091

9549

Coxarthrosis, primary, with hip surgery

1330

9820

1.30

17.77

2.8

2.9

0.25

0.31

e6/l

0.88

1303

9608

Benign lipomatous neoplasm

736

5254

1.42

17.72

3.1

2.5

0.29

0.28

e6/l

0.05

715

5110

Urticaria and erythema

929

6888

1.37

17.63

3.1

2.6

0.21

0.27

e6/l

1.14

901

6670

Injuries to the knee and lower leg

3519

17192

1.18

17.59

2.8

2.7

0.30

0.28

e6/l

0.39

3422

16704

Dementia in Alzheimer disease

538

3096

1.52

17.54

3.7

2.9

0.45

0.36

e6/l

0.51

530

3046

Varus deformity, not elsewhere classified

155

3.94

17.49

2.8

2.4

0.23

0.21

e6/l

0.04

149

Disorders of parathyroid gland

557

3742

1.50

17.46

4.7

2.7

0.25

0.33

e6/l

1.52

548

3635

Diabetic retinopathy

1044

4950

1.36

17.41

4.0

2.9

0.30

0.31

e6/l

0.09

1034

4851

Disturbance of activity and attention

226

1211

1.88

17.24

2.3

2.5

0.18

0.19

e6/l

0.12

220

1162

Cerebrovascular diseases

2147

12635

1.23

17.20

3.4

2.7

0.29

0.28

e6/l

0.13

2104

12328

Iron deficiency anaemia secondary to blood loss (chronic)

454

2974

1.56

17.20

3.9

2.7

0.34

0.31

e6/l

0.14

445

2905

Keratitis

934

6964

1.36

17.16

3.1

2.7

0.21

0.29

e6/l

1.69

912

6765

Diaphragmatic hernia

985

7407

1.35

17.15

3.0

2.8

0.21

0.30

e6/l

2.24

967

7216

Crohn's disease NAS

182

926

2.04

17.11

3.1

2.9

0.33

0.22

e6/l

0.79

177

898

Exclusions for E4_PCOS_BROAD

436

2835

1.57

16.95

3.4

2.7

0.32

0.27

e6/l

0.24

430

2752

Diabetic retinopathy, strict definition

557

3351

1.50

16.91

5.1

3.0

0.26

0.31

e6/l

0.40

548

3284

Superficial injury of lower leg

631

4424

1.45

16.84

3.0

2.6

0.35

0.26

e6/l

0.53

609

4293

Otitis externa, unspecified

289

1707

1.74

16.74

2.8

0.29

0.25

e6/l

0.27

278

1658

Disturbances of skin sensation

679

4828

1.43

16.73

2.9

2.5

0.23

0.26

e6/l

0.29

661

4666

Hypothyroidism, strict autoimmune, 3 medication purchases required

2419

13729

1.21

16.71

2.8

2.6

0.31

0.28

e6/l

0.34

2357

13291

Other noninflammatory disorders of vulva and perineum

219

1192

1.89

16.69

2.9

2.3

0.21

0.37

e6/l

1.35

211

1147

Vaginitis/vulvovaginitis/vulvitis/abscess of vulva

385

2442

1.61

16.67

2.9

2.3

0.26

e6/l

0.02

374

2330

Superficial injury of head

589

4086

1.47

16.65

2.8

2.7

0.34

0.31

e6/l

0.21

571

3960

Postmenopausal bleeding

643

2445

1.47

16.64

2.5

2.4

0.30

0.37

e6/l

0.61

618

2356

Nontoxic goitre/thyroid nodule

762

5534

1.40

16.63

2.9

2.6

0.22

0.31

e6/l

2.30

740

5371

Pulmonary embolism

814

5976

1.39

16.63

3.8

2.8

0.40

0.30

e6/l

0.97

795

5845

Chronic pancreatitis

346

2149

1.66

16.58

3.1

2.8

0.39

0.23

e6/l

0.69

339

2100

Pulmonary heart disease

814

5981

1.38

16.55

3.8

2.8

0.40

0.30

e6/l

0.98

795

5849

Other disorders of gingiva or/and edentulous alveolar ridge

156

763

2.13

16.49

5.4

2.5

0.26

0.25

e6/l

0.02

150

743

Spondyloarthritis

493

3314

1.52

16.41

2.8

2.5

0.38

0.29

e6/l

0.58

477

3209

Chondropathies

398

2557

1.59

16.39

3.1

2.7

0.16

0.27

e6/l

1.96

387

2475

Inflammatory bowel disease

833

6152

1.37

16.31

3.0

2.7

0.33

0.26

e6/l

0.52

809

5977

Phlebitis and thrombophlebitis (not including DVT)

613

4307

1.45

16.29

3.6

2.6

0.28

0.29

e6/l

0.01

600

4186

Other and unspecified tonsillitis

808

5018

1.38

16.23

2.5

2.4

0.30

0.25

e6/l

0.40

787

4852

Open wound of wrist and hand

1162

8913

1.31

16.20

2.8

2.7

0.33

0.25

e6/l

0.88

1135

8699

Hyperparathyroidism

491

3275

1.51

16.10

4.9

2.7

0.25

0.33

e6/l

1.24

483

3183

Heart failure and bmi 25plus

901

4619

1.37

16.06

3.6

2.6

0.39

0.30

e6/l

0.73

889

4534

All influenza (not pneumonia)

398

2569

1.58

16.04

3.7

2.5

0.27

0.25

e6/l

0.13

389

2506

857

5647

1.37

15.97

3.2

2.9

0.35

0.31

e6/l

0.28

844

5537

Infections of genitourinary tract in pregnancy

234

1321

1.82

15.87

3.0

2.4

0.28

0.26

e6/l

0.10

225

1261

Coronary atherosclerosis

1938

10234

1.23

15.79

3.4

2.7

0.32

0.28

e6/l

0.57

1914

9981

Other specified/unspecified arthritis

697

5032

1.41

15.75

3.5

2.6

0.20

0.28

e6/l

1.45

674

4901

Undetermined asthma, excluding more controls

333

2070

1.64

15.73

3.8

2.4

0.26

0.27

e6/l

0.05

321

2013

Early onset COPD, excluding more controls

572

3993

1.46

15.69

3.7

2.5

0.36

0.27

e6/l

0.84

562

3911

Other problems related to primary support group, including family circumstances

272

1565

1.73

15.66

4.3

2.5

0.25

0.23

e6/l

0.11

262

1503

Other gastritis (incl. Duodenitis)

633

4513

1.43

15.51

3.1

2.8

0.29

e6/l

0.01

621

4401

COPD

1329

8668

1.28

15.49

3.6

2.8

0.32

0.29

e6/l

0.34

1301

8521

Pulmonary heart disease, diseases of pulmonary circulation

881

6623

1.35

15.43

3.8

2.8

0.39

0.30

e6/l

0.85

861

6478

Spondylopathies (FG)

357

2269

1.61

15.42

2.7

2.4

0.36

0.26

e6/l

0.46

342

2192

Lyme disease

301

4815

0.61

15.37

1.8

2.7

0.28

e6/l

0.02

288

4686

Gout, strict definition

543

3784

1.47

15.33

4.4

2.9

0.29

0.30

e6/l

0.06

535

3724

Melanocytic naevi of trunk

314

1943

1.66

15.27

4.1

2.8

0.24

0.25

e6/l

0.06

305

1891

Organic, including symptomatic, mental disorders

1414

8129

1.27

15.26

3.2

2.9

0.36

0.30

e6/l

0.85

1393

7982

Diseases of salivary glands

504

3456

1.49

15.24

2.8

2.6

0.28

0.33

e6/l

0.26

494

3359

Phobic anxiety disorders

303

1855

1.66

15.18

2.9

2.3

0.21

0.23

e6/l

0.11

291

1771

Polyneuropathies and other disorders of the peripheral nervous system

615

4385

1.43

15.17

4.1

2.9

0.25

0.28

e6/l

0.32

606

4300

Other metabolic disorders

308

1899

1.66

15.10

3.3

2.2

0.30

0.26

e6/l

0.17

303

1826

Superficial injury of ankle and foot

288

1746

1.69

15.10

3.0

2.6

0.20

0.25

e6/l

0.27

281

1687

Somatoform disorder

410

2703

1.55

15.05

3.4

2.5

0.17

0.27

e6/l

2.24

389

2611

Undetermined asthma

333

2094

1.62

15.02

3.8

2.4

0.26

0.28

e6/l

0.07

321

2036

Cervicocranial syndrome

283

1712

1.69

15.02

3.2

2.6

0.18

0.32

e6/l

1.74

272

1652

Varicose veins

1813

11229

1.23

15.01

2.8

2.7

0.32

0.29

e6/l

0.33

1771

10932

Hyperkinetic disorders

231

1303

1.79

14.94

2.3

2.6

0.18

0.20

e6/l

0.17

225

1251

Other chronic obstructive pulmonary disease

1281

8426

1.28

14.93

3.6

2.9

0.32

0.29

e6/l

0.32

1253

8285

609

4116

1.43

14.79

3.2

2.9

0.38

0.33

e6/l

0.34

599

4033

Acute pancreatitis (for exclusion)

555

3902

1.45

14.79

3.3

2.9

0.40

0.28

e6/l

0.71

546

3817

Car occupant injured in other and unspecified transport accidents

474

3231

1.49

14.78

2.6

0.17

0.26

e6/l

1.86

460

3118

Oter anti-inflammatory and antirheumatic agents, non-steroids

752

3040

1.39

14.73

3.2

3.1

0.32

e6/l

0.07

730

2992

Alzheimer’s disease (Atypical or mixed), excluding more controls

248

1255

1.77

14.71

4.1

2.8

0.59

0.42

e6/l

0.30

243

1236

Trochanteric bursitis

343

2190

1.60

14.61

3.0

2.4

0.21

0.33

e6/l

1.66

331

2121

Pruritus

283

1726

1.68

14.59

3.4

2.7

0.31

0.30

e6/l

0.08

277

1668

Gout, unspecified

602

4318

1.43

14.45

4.3

2.9

0.30

e6/l

0.01

594

4248

Seborrhoeic keratosis

612

4398

1.42

14.43

3.9

2.8

0.24

0.30

e6/l

0.59

598

4296

Other and unspecified polyneuropathies, also in other diseases

541

3810

1.45

14.37

4.3

2.9

0.26

0.28

e6/l

0.20

533

3733

Other noninfective gastroenteritis and colitis

628

4526

1.41

14.35

3.2

2.7

0.28

0.29

e6/l

0.04

604

4407

Neuralgia and neuritis, unspecified

144

720

2.08

14.35

2.9

2.7

0.15

0.31

e6/l

2.12

138

698

Adhesive capsulitis of shoulder

456

3107

1.50

14.34

3.5

2.6

0.23

0.32

e6/l

1.02

445

3027

Chondrocostal junction syndrome [Tietze]

116

536

2.27

14.31

3.2

2.7

0.17

0.31

e6/l

0.74

110

518

Adenomyosis (Endometriosis of uterus)

304

1894

1.64

14.30

3.2

2.4

0.19

0.36

e6/l

2.72

294

1831

Other spirochaetal diseases

312

4865

0.63

14.25

1.8

2.7

0.29

0.28

e6/l

0.07

299

4734

AV-block

521

3304

1.46

14.24

3.1

2.8

0.34

0.28

e6/l

0.56

512

3245

Benign neoplasm of other and ill-defined parts of digestive system

430

2902

1.51

14.19

3.4

2.5

0.24

0.27

e6/l

0.24

424

2817

Schizophrenia

404

2691

1.53

14.15

3.0

2.7

0.38

0.26

e6/l

0.71

397

2607

Iridocyclitis

583

4166

1.42

14.12

3.0

2.6

0.22

0.30

e6/l

1.31

571

4051

In situ neoplasms

963

7429

1.31

14.07

4.5

2.7

0.24

0.29

e6/l

0.60

952

7223

Polymyalgia rheumatica

379

2506

1.55

13.96

3.1

2.7

0.22

0.33

e6/l

1.55

368

2458

Methotrexate

384

2541

1.54

13.92

3.0

2.4

0.19

0.29

e6/l

1.77

371

2462

Viral haemorrhagic fevers, not elsewhere classified/unspecified

223

1295

1.78

13.92

2.9

2.8

0.55

0.28

e6/l

1.02

218

1263

Streptococcal septicaemia

238

1408

1.74

13.89

4.0

2.6

0.33

0.28

e6/l

0.28

232

1381

Visual disturbances and blindness

1344

10807

1.26

13.89

3.1

2.7

0.25

0.28

e6/l

0.71

1304

10524

Haemangioma and lymphangioma, any site

217

1249

1.78

13.88

3.0

2.6

0.17

0.24

e6/l

0.77

211

1207

Benign neoplasm of other and unspecified endocrine glands

338

2180

1.59

13.87

3.4

2.8

0.22

0.27

e6/l

0.39

332

2126

Other diseases of lip and oral mucosa

428

2906

1.50

13.73

2.9

2.6

0.34

0.32

e6/l

0.05

414

2821

Haemangioma, any site

205

1165

1.81

13.73

3.0

2.5

0.17

0.24

e6/l

0.81

199

1124

Visual disturbances

1239

9887

1.27

13.72

3.1

2.7

0.23

0.28

e6/l

0.98

1203

9630

Rheumatoid arthritis, including avohilmo

1007

7840

1.30

13.69

2.9

2.7

0.20

0.30

e6/l

4.58

982

7629

Other chronic obstructive pulmonary disease, including avohilmo

1542

10469

1.24

13.61

3.5

2.9

0.31

0.29

e6/l

0.24

1509

10282

Benign neoplasm: Adrenal gland

191

1068

1.85

13.60

3.0

2.5

0.29

0.23

e6/l

0.35

191

1036

Other bursopathies

350

2286

1.57

13.55

3.0

2.7

0.45

0.34

e6/l

0.46

342

2235

Substance abuse, excluding more controls

1551

11088

1.24

13.54

3.1

2.7

0.36

0.26

e6/l

1.95

1514

10811

Spondylolisthesis/Spondylolysis

460

3175

1.48

13.53

2.7

2.5

0.29

0.32

e6/l

0.18

445

3075

Urticaria

720

5357

1.36

13.52

3.0

2.5

0.22

0.27

e6/l

0.66

697

5181

Ulcerative colitis, NAS

352

2301

1.56

13.52

3.2

2.6

0.43

0.26

e6/l

0.76

342

2234

Suicide or other Intentional self-harm

597

4313

1.40

13.51

2.9

2.5

0.26

e6/l

0.01

582

4164

Arthropod-borne viral fevers and viral haemorrhagic fevers

265

1625

1.68

13.48

2.8

0.51

0.28

e6/l

1.04

260

1589

Adverse effects, not elsewhere classified

467

3237

1.47

13.40

2.8

2.6

0.23

0.26

e6/l

0.34

450

3132

Pedal cyclist injured in other and unspecified transport accidents

279

1734

1.65

13.37

2.7

0.27

0.28

e6/l

0.04

269

1685

Inguinal hernia

1770

9861

1.22

13.36

2.9

2.8

0.28

0.29

e6/l

0.12

1735

9642

Endometriosis of ovary

362

2377

1.54

13.35

2.6

2.2

0.28

0.35

e6/l

0.52

351

2286

Squamous cell neoplasms and carcinomas of the skin, excluding all cancers (controls excluding all cancers)

342

2233

1.57

13.32

3.6

2.6

0.38

0.32

e6/l

0.30

332

2187

Persons with potential health hazards related to socioeconomic and psychosocial circumstances

652

4734

1.38

13.30

3.6

2.5

0.21

0.26

e6/l

0.67

629

4562

Any dementia

1086

6010

1.29

13.27

3.4

2.9

0.42

0.30

e6/l

1.11

1071

5902

Benign paroxysmal vertigo

741

5561

1.35

13.26

2.7

0.23

0.30

e6/l

0.89

721

5416

Other disorders of skin and subcutaneous tissue, not elsewhere classified

390

2620

1.52

13.25

4.0

2.7

0.51

0.29

e6/l

1.41

384

2554

Other fall from one level to another

573

4127

1.41

13.24

3.0

2.8

0.29

0.27

e6/l

0.09

557

4022

Other disorders of veins

566

7776

0.72

13.13

2.6

0.28

0.29

e6/l

0.02

529

7546

Fibrosis and cirrhosis of liver

210

1223

1.78

13.06

3.4

2.8

0.34

0.31

e6/l

0.08

205

1193

Other shoulder lesions

234

1399

1.71

13.06

2.9

2.5

0.14

0.29

e6/l

2.41

227

1355

Acetic acid derivatives and related substances

888

3514

1.33

13.05

2.8

3.0

0.34

0.32

e6/l

0.11

860

3454

Direct fill therapy

332

2161

1.57

13.03

4.0

2.7

0.26

0.27

e6/l

0.05

325

2105

Exclusions for E4_PCOS_CONSORTIUM

1817

9444

1.21

12.98

2.8

2.5

0.28

0.27

e6/l

0.10

1755

9083

Traumatic subdural haemorrhage

372

2444

1.53

12.97

3.1

2.8

0.40

0.32

e6/l

0.40

366

2404

Superficial injury of forearm

239

1444

1.70

12.82

3.5

2.7

0.17

0.26

e6/l

1.60

234

1404

Other keratitis

276

1731

1.63

12.76

3.3

2.7

0.16

0.29

e6/l

2.08

267

1681

malignant neoplasm of female genital organs

356

2368

1.54

12.69

2.8

2.6

0.22

0.34

e6/l

1.87

343

2297

Other specified and unspecified personality disorders

222

1319

1.72

12.68

3.3

2.6

0.45

0.22

e6/l

0.67

217

1275

Radiculopathy

454

3174

1.46

12.55

3.5

2.7

0.25

0.34

e6/l

1.08

439

3085

Glaucoma suspect

953

7459

1.30

12.54

3.2

2.8

0.30

e6/l

0.00

930

7276

Other diseases of upper respiratory tract

3385

15410

1.15

12.51

2.8

2.7

0.26

0.29

e6/l

0.70

3289

15000

Mycoses

668

4983

1.36

12.46

3.5

2.7

0.40

0.27

e6/l

1.13

654

4854

Retinal vascular occlusion

349

2326

1.54

12.46

3.6

2.9

0.18

0.32

e6/l

2.73

344

2286

Other forms of systemic lupus erythematosus

130

3.69

12.45

5.7

3.0

0.11

0.22

e6/l

0.54

124

COPD, hospital admissions

1317

9045

1.25

12.41

3.6

2.9

0.32

0.29

e6/l

0.31

1288

8891

Other Crohn's disease

173

965

1.84

12.38

2.5

2.7

0.32

0.19

e6/l

0.67

168

935

Fissure and fistula of anal and rectal regions

610

4490

1.38

12.37

2.6

0.23

0.28

e6/l

0.76

598

4368

Malignant neoplasm of ovary, excluding all cancers (controls excluding all cancers)

162

889

1.88

12.28

2.4

2.5

0.27

e6/l

0.01

155

854

Other female pelvic inflammatory diseases

378

2562

1.50

12.25

2.9

2.4

0.27

0.25

e6/l

0.09

368

2464

Follicular cysts of skin and subcutaneous tissue

466

3290

1.44

12.21

2.9

2.7

0.19

0.29

e6/l

1.74

452

3199

Any dementia, excluding more controls

1006

5491

1.29

12.17

3.4

2.8

0.40

0.30

e6/l

0.83

992

5386

Seropositive rheumatoid arthritis, strict definition

387

2642

1.50

12.16

2.8

2.7

0.15

0.30

e6/l

3.85

382

2566

Anterior Iridocyclitis

517

3719

1.41

12.15

3.0

2.7

0.21

0.29

e6/l

1.43

507

3609

Endometriosis of pelvic peritoneum

330

2149

1.54

12.06

2.5

2.2

0.14

0.34

e6/l

5.34

322

2055

Benign neoplasm: Sigmoid colon

446

3133

1.45

12.05

3.0

2.6

0.37

0.28

e6/l

0.46

435

3066

Correction of physiology of bite - demanding therapy visit

173

974

1.83

12.03

2.3

2.7

0.27

e6/l

0.01

166

940

Ankylosing spondylitis

232

1417

1.68

11.98

2.7

0.45

0.32

e6/l

0.36

222

1368

Idiopathic gout

277

1776

1.61

11.90

4.5

2.9

0.28

0.30

e6/l

0.09

272

1745

Ulcerative colitis

621

4613

1.37

11.90

3.0

2.6

0.37

0.25

e6/l

0.85

601

4481

Bronchitis, not specified as acute or chronic

240

1482

1.66

11.90

3.8

2.7

0.38

0.30

e6/l

0.27

235

1445

Retinal vascular disorders

352

2375

1.52

11.85

3.6

2.9

0.18

0.32

e6/l

2.79

346

2334

Substance use, excluding alcohol

458

3244

1.43

11.73

3.4

2.6

0.46

0.25

e6/l

1.29

444

3138

Allergic contact dermatitis

326

2164

1.54

11.72

2.7

2.5

0.21

0.26

e6/l

0.37

320

2082

Total colectomy operation

120

608

2.05

11.66

3.6

2.7

0.55

0.18

e6/l

0.99

113

589

Total colectomy

120

608

2.05

11.66

3.6

2.7

0.55

0.18

e6/l

0.99

113

589

Acute and subacute iridocyclitis

485

3478

1.42

11.63

3.0

2.6

0.22

0.30

e6/l

1.32

477

3377

Fracture of foot, except ankle

562

4128

1.38

11.58

3.5

2.6

0.25

0.26

e6/l

0.04

542

4002

Other and unspecified visual disturbances

241

1501

1.65

11.58

2.6

2.8

0.23

0.28

e6/l

0.48

233

1455

Other and unspecified local infections of skin and subcutaneous tissue

247

1548

1.64

11.57

3.5

2.8

0.18

0.28

e6/l

1.28

242

1508

Diseases of liver

882

6911

1.29

11.52

3.4

2.8

0.38

0.27

e6/l

1.14

860

6743

Other diseases of liver

436

3075

1.44

11.52

3.6

2.7

0.35

0.27

e6/l

0.33

423

2987

Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium

993

6882

1.27

11.51

3.0

2.3

0.26

0.27

e6/l

0.05

953

6573

Seborrhoeic dermatitis

265

1694

1.61

11.44

3.1

2.9

0.27

0.31

e6/l

0.19

257

1658

Skin changes due to chronic exposure to nonionizing radiation

1073

8148

1.26

11.42

3.6

2.9

0.22

0.31

e6/l

3.34

1060

7989

Excessive vomiting in pregnancy

188

1100

1.75

11.41

2.5

2.3

0.26

0.24

e6/l

0.12

180

1045

Malignant neoplasm of skin, excluding all cancers (controls excluding all cancers)

1418

7961

1.23

11.41

3.2

2.5

0.27

0.29

e6/l

0.23

1383

7737

Any prescribed medicine buy

7.74

11.40

2.3

3.2

0.01

0.38

e6/l

0.58

Other specified disorders of kidney and ureter

104

506

2.16

11.37

6.8

2.7

0.25

0.23

e6/l

0.12

104

492

Open wound of lower leg

369

2532

1.49

11.32

3.3

2.7

0.32

0.27

e6/l

0.27

361

2470

Mandibular retrognathia

155

857

1.85

11.32

3.4

2.8

0.25

0.23

e6/l

0.07

148

825

Other specified/unspecified inflammatory spondylopathies

122

627

2.01

11.30

2.7

2.6

0.25

0.26

e6/l

0.04

114

600

Other and unspecified nonorganic psychotic disorders

434

3068

1.43

11.24

2.9

2.5

0.43

0.25

e6/l

1.14

425

2958

Fracture at wrist and hand level

841

6567

1.29

11.19

2.7

0.34

0.26

e6/l

0.63

821

6402

Explicit bacterial Sepsis

267

1717

1.59

11.18

3.9

2.6

0.37

0.27

e6/l

0.64

260

1675

Allergic asthma (mode), excluding more controls

542

3904

1.38

11.14

2.5

2.2

0.25

0.27

e6/l

0.11

522

3771

Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk

304

2012

1.54

11.14

2.8

2.4

0.27

e6/l

0.02

294

1947

Excessive attrition of teeth

1028

4422

1.27

11.12

3.1

2.5

0.18

0.26

e6/l

1.97

1002

4305

Atherosclerosis, excluding cerebral and coronary sclerosis

1208

7855

1.24

11.10

3.9

2.8

0.35

0.29

e6/l

0.63

1187

7716

Coeliac disease

299

1974

1.55

11.09

3.1

2.8

0.17

0.28

e6/l

1.88

286

1914

1125

8566

1.25

11.09

3.6

2.9

0.23

0.32

e6/l

3.07

1111

8393

Noninfectious colitis NAS

333

2249

1.51

11.07

3.1

2.7

0.27

0.28

e6/l

0.02

318

2180

Nontoxic multinodular goitre

486

3521

1.40

11.00

3.2

2.6

0.18

0.29

e6/l

3.33

473

3416

Later onset COPD, excluding more controls

621

3631

1.36

10.99

3.7

2.7

0.29

e6/l

0.03

605

3571

Flat foot [pes planus] (acquired)

228

1420

1.64

10.94

3.4

2.5

0.37

0.27

e6/l

0.42

222

1373

Multiple myeloma and malignant plasma cell neoplasms

131

702

1.94

10.86

3.1

2.5

0.31

0.27

e6/l

0.19

131

688

Other local infections of skin and subcutaneous tissue

259

1667

1.59

10.85

3.4

2.8

0.18

0.27

e6/l

1.38

254

1621

Cerebral cysts

147

815

1.86

10.85

3.5

2.6

0.32

0.24

e6/l

0.25

142

786

Other symptoms and signs involving general sensations and perceptions

113

576

2.04

10.84

3.4

2.6

0.60

0.36

e6/l

0.46

113

555

Injuries to the elbow and forearm

1792

13710

1.19

10.84

2.8

2.6

0.29

0.28

e6/l

0.09

1748

13292

TMD related pain

441

2.19

10.80

2.9

2.6

0.77

0.17

e6/l

0.98

424

Other disorders of conjunctiva

378

2634

1.47

10.79

3.5

2.8

0.23

0.32

e6/l

0.89

373

2575

Other specified/unspecified bacterial intestinal infections

178

1048

1.75

10.72

3.3

2.8

0.16

0.33

e6/l

1.90

173

1019

Internal derangement of knee

975

7776

1.26

10.70

2.7

2.6

0.29

e6/l

0.00

946

7567

Alcohol abuse, main dg, excluding more controls

371

2576

1.47

10.70

2.7

0.38

0.26

e6/l

0.66

361

2509

Mental and behavioural disorders due to multiple drug use and use of multiple drugs and use of other psychoactive substances

161

921

1.79

10.62

3.1

2.6

0.47

0.16

e6/l

1.18

154

890

Benign neoplasm: Rectum, anus and anal canal

538

3990

1.37

10.61

2.8

2.9

0.18

0.29

e6/l

2.77

524

3905

Dislocation, sprain and strain of joints and ligaments at wrist and hand level

663

5058

1.33

10.60

2.9

2.6

0.20

0.26

e6/l

1.03

638

4905

Acute suppurative otitis media

575

4005

1.35

10.60

3.2

2.4

0.23

0.28

e6/l

0.44

558

3862

Multiple myeloma, excluding all cancers (controls excluding all cancers)

131

708

1.92

10.58

3.1

2.6

0.31

0.32

e6/l

0.07

131

694

Sequelae of cerebrovascular disease

991

6974

1.26

10.58

3.8

2.9

0.33

0.31

e6/l

0.12

976

6838

Polyp of the female genital tract

688

3035

1.33

10.57

2.3

0.26

0.35

e6/l

1.40

646

2920

Non-invasive ventilation

500

3433

1.39

10.56

2.6

2.3

0.34

0.25

e6/l

1.08

489

3321

Abnormal findings on diagnostic imaging of lung

1311

10553

1.22

10.54

3.5

2.8

0.29

0.30

e6/l

0.12

1287

10325

Enteropathic arthropathies

324

2.40

10.51

2.9

2.4

0.66

0.21

e6/l

0.52

315

Colorectal adenocarcinoma, excluding all cancers (controls excluding all cancers)

495

3628

1.39

10.48

3.3

2.6

0.34

0.32

e6/l

0.19

488

3553

COPD, hospital admission 2, with asthma infections

922

6261

1.27

10.47

3.9

2.9

0.38

0.31

e6/l

0.69

902

6156

COPD, early/later onset

1306

9106

1.22

10.44

3.6

2.9

0.32

0.29

e6/l

0.32

1278

8950

Generalized anxiety disorder

330

2249

1.49

10.43

3.1

2.4

0.20

0.23

e6/l

0.25

322

2152

Other malignant neoplasms of skin (=non-melanoma skin cancer), excluding all cancers (controls excluding all cancers)

1275

7180

1.23

10.43

3.4

2.6

0.28

0.30

e6/l

0.17

1243

6990

Diseases of external ear

860

6805

1.28

10.42

2.9

2.8

0.30

0.28

e6/l

0.11

834

6634

Fracture of lower leg, including ankle

1420

11789

1.21

10.40

2.9

2.7

0.31

0.28

e6/l

0.46

1390

11457

Disorders of muscles

252

1628

1.58

10.37

3.3

2.6

0.33

0.30

e6/l

0.09

247

1579

Other otitis externa (chronic)

173

1020

1.75

10.37

3.2

2.8

0.26

0.29

e6/l

0.17

168

993

Examination and encounter for administrative purposes

122

648

1.95

10.37

3.5

2.4

0.17

0.25

e6/l

0.65

122

629

Ocular pain

194

1178

1.69

10.35

2.9

2.6

0.27

0.25

e6/l

0.07

187

1142

Other diseases of pleura

1280

9365

1.22

10.33

3.7

2.9

0.33

0.29

e6/l

0.45

1259

9198

Parkinson's disease, strict definition, excluding more controls

353

2400

1.47

10.33

3.1

2.7

0.27

0.30

e6/l

0.18

344

2358

Haemorrhage in early pregnancy

593

4359

1.34

10.33

2.7

2.3

0.23

0.25

e6/l

0.12

569

4163

Actinic keratosis

1037

7968

1.25

10.31

3.7

2.9

0.22

0.31

e6/l

3.12

1025

7815

Lateral epicondylitis

319

2169

1.50

10.27

2.6

2.5

0.20

0.30

e6/l

1.08

313

2108

Allergic asthma (mode)

542

3957

1.36

10.27

2.5

2.2

0.25

0.27

e6/l

0.11

522

3819

Dementia, including avohilmo

1240

7026

1.23

10.23

3.1

2.9

0.37

0.31

e6/l

0.76

1220

6907

Dental caries 3 and operation codes

2757

12358

1.15

10.20

2.9

2.7

0.25

0.30

e6/l

1.50

2682

12023

Gingivitis and periodontal diseases

2647

11906

1.15

10.19

2.8

2.6

0.23

0.30

e6/l

2.29

2579

11574

Injury of eye and orbit

341

2353

1.47

10.18

3.1

2.7

0.24

0.28

e6/l

0.28

333

2280

Unstable angina pectoris

1125

7611

1.24

10.15

3.4

2.9

0.24

0.29

e6/l

0.93

1103

7488

Parkinson's disease, excluding more controls

376

2584

1.45

10.03

3.1

2.8

0.26

0.31

e6/l

0.27

367

2538

Focal epilepsy

526

3919

1.36

9.99

3.0

2.8

0.37

0.27

e6/l

0.53

515

3821

Duodenal ulcer

320

2198

1.49

9.91

3.2

2.9

0.49

0.29

e6/l

1.19

315

2152

Degenerative macular diseases

336

2331

1.47

9.90

3.0

2.8

0.34

0.33

e6/l

0.03

328

2287

Benign neoplasm: Rectum

475

3497

1.38

9.89

2.8

2.9

0.16

0.29

e6/l

3.81

462

3424

Malnutrition

309

2.41

9.87

4.9

3.3

0.24

0.20

e6/l

0.22

301

Oxicams

735

3233

1.31

9.84

2.6

3.1

0.26

0.32

e6/l

0.52

721

3180

Fall on same level involving ice and snow

1444

12126

1.20

9.81

2.8

2.7

0.32

0.28

e6/l

0.43

1405

11793

Other disorders of eyelid

1167

9285

1.23

9.78

3.1

2.8

0.25

0.31

e6/l

1.08

1131

9061

Reactive arthropathies, FINNGEN

176

1058

1.70

9.78

3.3

2.5

0.43

0.24

e6/l

0.46

170

1026

Seropositive rheumatoid arthritis, wide

683

5298

1.31

9.77

2.9

2.7

0.19

0.30

e6/l

4.06

667

5158

Dental pulpitis 2

2211

9770

1.17

9.75

3.0

2.7

0.27

0.31

e6/l

0.61

2150

9518

Other/unspecified seropositive rheumatoid arthritis (ICD-10)

664

5134

1.31

9.74

2.9

2.7

0.19

0.29

e6/l

3.61

648

5001

Malignant neoplasm of digestive organs

1056

8484

1.24

9.74

3.1

2.9

0.50

0.29

e6/l

2.88

1045

8320

Wet age-related macular degeneration

474

3436

1.38

9.67

3.1

2.9

0.32

0.34

e6/l

0.18

468

3368

Non-allergic asthma (mode), excluding more controls

473

3454

1.37

9.61

2.7

2.4

0.17

0.29

e6/l

3.10

456

3361

COPD related to multimorbidity

1121

7760

1.23

9.47

3.6

2.9

0.34

0.30

e6/l

0.45

1098

7634

Fracture of shoulder and upper arm

883

7087

1.26

9.43

3.1

2.8

0.31

0.29

e6/l

0.18

862

6907

Triptan medication for migraine, single purchase ok

1884

10935

1.17

9.43

2.6

2.5

0.21

0.27

e6/l

1.48

1818

10558

Migraine, single triptan purchase ok & required. ICD-code if available is included

1884

10935

1.17

9.43

2.6

2.5

0.21

0.27

e6/l

1.48

1818

10558

Haemangioma, any site

205

1294

1.62

9.41

3.0

2.8

0.17

0.30

e6/l

1.39

199

1254

Major coronary heart disease event

1981

11387

1.17

9.40

3.3

2.8

0.32

0.29

e6/l

0.47

1946

11144

DVT of lower extremities

499

3729

1.36

9.39

3.9

2.7

0.31

0.28

e6/l

0.12

484

3644

Myocardial infarction

1418

8543

1.20

9.39

3.4

2.7

0.35

0.29

e6/l

0.83

1396

8373

Gastric ulcer

485

3609

1.37

9.39

3.4

2.8

0.33

0.30

e6/l

0.17

478

3532

Other/unspecified seropositive rheumatoid arthritis

674

5248

1.30

9.38

2.9

2.7

0.19

0.30

e6/l

3.87

658

5113

Malignant neoplasm of corpus uteri, excluding all cancers (controls excluding all cancers)

218

1397

1.60

9.38

3.2

2.5

0.22

0.33

e6/l

1.28

211

1348

Pedal cyclist injured in transport accident

523

3933

1.35

9.36

2.7

0.30

0.26

e6/l

0.35

505

3811

Sulfasalazine

723

5677

1.29

9.36

2.7

2.5

0.20

0.28

e6/l

1.66

706

5506

Diseases of vocal cords and larynx+other diseases of upper respiratory tract, no elsewhere classified

1351

11089

1.20

9.35

2.7

0.29

0.27

e6/l

0.21

1320

10798

Acute laryngitis and tracheitis

250

1624

1.54

9.27

2.8

2.3

0.19

0.22

e6/l

0.23

240

1557

Heart failure and coronary heart disease

964

5825

1.25

9.24

3.9

2.9

0.39

0.30

e6/l

1.32

941

5741

Secondary uncertain malignant neoplasm

341

2403

1.45

9.24

2.8

2.9

0.41

0.29

e6/l

1.06

336

2357

Myocardial infarction, without ST-elevation

1135

8652

1.22

9.24

3.6

2.9

0.32

0.30

e6/l

0.23

1115

8513

Vulvovaginal ulceration/inflammation in other diseases

128

716

1.83

9.19

3.9

2.4

0.25

0.27

e6/l

0.09

123

684

Isolated proteinuria with specified morphological lesion

185

2.82

9.15

8.5

2.6

0.15

0.18

e6/l

0.18

177

Metatarsalgia

222

1436

1.58

9.14

2.6

2.5

0.15

0.28

e6/l

2.02

212

1389

Other/unspecified synovitis and tenosynovitis

282

1919

1.50

9.13

2.5

0.23

0.30

e6/l

0.61

266

1865

Intestinal adhesions without obstruction

210

1344

1.60

9.12

3.3

2.8

0.35

0.32

e6/l

0.12

205

1308

Complications of internal orthopaedic prosthetic devices, implants and grafts

576

4414

1.32

9.11

3.2

2.7

0.32

0.29

e6/l

0.17

571

4307

IBD patients in KELA-register

544

4131

1.33

9.10

2.9

2.6

0.36

0.26

e6/l

0.65

530

4000

Haemangioma and lymphangioma, any site

217

1400

1.59

9.08

3.0

2.8

0.17

0.30

e6/l

1.50

211

1358

Gestational [pregnancy-induced] oedema and proteinuria without hypertension

198

1250

1.62

9.07

3.5

2.4

0.28

e6/l

0.03

191

1203

Fracture of lumbar spine and pelvis

545

4141

1.33

9.06

3.5

2.8

0.37

0.31

e6/l

0.44

528

4045

Diagnoses used for exclusion with ILD

675

5283

1.29

9.05

3.7

2.8

0.20

0.29

e6/l

2.15

663

5158

Fracture of skull and facial bones

503

3783

1.35

9.02

3.0

2.7

0.38

0.28

e6/l

0.66

493

3671

Antenatal screening

490

2038

1.37

9.00

2.3

2.2

0.20

0.26

e6/l

0.48

465

1936

Benign neoplasm: Adrenal gland

191

1201

1.64

9.00

3.0

2.8

0.29

0.26

e6/l

0.13

191

1170

Dental pulpitis 4, only avohilmo

3279

15254

1.13

8.98

2.8

2.7

0.23

0.29

e6/l

2.35

3185

14840

Benign neoplasm: Caecum

245

1629

1.54

8.97

3.1

2.5

0.22

0.27

e6/l

0.39

237

1589

Faecal incontinence

198

1254

1.61

8.95

4.0

2.4

0.19

0.34

e6/l

1.23

191

1210

Glaucoma

1509

11253

1.19

8.92

3.1

2.8

0.28

0.30

e6/l

0.17

1479

10989

Other enthesopathy of foot (+metatarsalgia)

233

1532

1.55

8.91

2.6

2.5

0.16

0.28

e6/l

1.73

223

1482

Coronary angioplasty

1101

6977

1.23

8.88

3.5

2.8

0.34

0.29

e6/l

0.53

1085

6854

Major coronary heart disease event excluding revascularizations

1824

10844

1.17

8.79

3.4

2.8

0.33

0.29

e6/l

0.56

1790

10627

Inflammatory bowel disease, strict (require KELA)

544

4154

1.33

8.77

2.9

2.6

0.36

0.25

e6/l

0.72

530

4021

Reactive arthropathies

218

1422

1.56

8.68

3.4

2.5

0.38

0.28

e6/l

0.27

209

1379

Other benign neoplasms of skin

952

7790

1.23

8.62

2.9

2.8

0.23

0.29

e6/l

1.44

935

7585

Alcohol use disorder, ICD-based

1103

9158

1.22

8.60

3.1

2.8

0.32

0.27

e6/l

0.68

1080

8945

Brachial plexus disorders

211

1370

1.57

8.57

2.2

2.4

0.20

0.25

e6/l

0.31

200

1311

Persistent mood disorders

463

3468

1.35

8.57

3.2

2.5

0.24

0.28

e6/l

0.41

447

3363

Colorectal cancer

629

4920

1.30

8.56

3.2

2.9

0.39

0.29

e6/l

0.98

621

4827

Retinal detachments and breaks

918

7496

1.24

8.52

3.3

2.8

0.21

0.30

e6/l

2.68

896

7339

Amenorrhoea

138

806

1.74

8.52

2.8

2.2

0.28

0.29

e6/l

0.02

132

765

Burns and corrosions

318

2244

1.44

8.51

2.8

0.19

0.27

e6/l

1.16

312

2186

Other embolism and thrombosis

334

2381

1.43

8.50

3.6

2.7

0.29

0.26

e6/l

0.15

322

2322

Infectious mononucleosis

173

1074

1.64

8.47

2.6

2.4

0.34

0.18

e6/l

1.04

166

1030

Suppurative and unspecified otitis media

825

5900

1.25

8.34

3.0

2.5

0.23

0.27

e6/l

0.52

801

5714

Other congenital malformations

187

1188

1.60

8.33

2.7

2.8

0.33

0.23

e6/l

0.43

179

1148

Benign neoplasm of mouth and pharynx

247

1670

1.51

8.32

2.6

2.5

0.29

0.28

e6/l

0.04

241

1625

Non-allergic asthma (mode)

473

3537

1.34

8.29

2.7

2.4

0.17

0.28

e6/l

2.76

456

3441

Benign neoplasm: Pancreas

359

2.16

8.29

3.5

2.4

0.06

0.21

e6/l

2.78

348

Ménière disease

241

1625

1.52

8.28

2.5

2.7

0.13

0.31

e6/l

3.46

232

1581

Other and unspecified nerve root and plexus disorders, also in other diseases

431

3214

1.36

8.25

2.6

0.27

0.28

e6/l

0.07

413

3118

Dislocation, sprain and strain of joints and ligaments of shoulder girdle

707

5628

1.27

8.25

2.8

2.7

0.23

0.28

e6/l

0.65

690

5481

Dental pulpitis 1, only avohilmo

3270

15298

1.12

8.20

2.8

2.7

0.23

0.29

e6/l

2.11

3175

14882

Enthesopathies of lower limb, excluding foot

505

3856

1.33

8.18

3.0

2.6

0.21

0.31

e6/l

1.97

482

3728

Other obstetric conditions, not elsewhere classified

649

3298

1.29

8.17

2.6

2.2

0.21

0.22

e6/l

0.19

616

3133

Type 1 diabetes, strict definition, subgroup 1

151

912

1.68

8.17

2.9

2.4

0.18

0.12

e6/l

0.59

146

870

Myocardial infarction, strict

1323

8162

1.19

8.16

3.4

2.8

0.36

0.28

e6/l

1.01

1301

8007

Type 1 diabetes, definitions combined

204

1325

1.56

8.14

3.8

2.5

0.23

0.19

e6/l

0.26

198

1274

Dental caries 3

2520

11370

1.14

8.12

2.9

2.7

0.27

0.30

e6/l

0.41

2443

11076

Bilateral sagittal split ramus osteotomy operation

436

2.01

8.08

1.8

2.5

0.13

0.15

e6/l

0.17

412

Alzheimer’s disease (Atypical or mixed)

252

1721

1.50

8.06

4.1

3.0

0.58

0.35

e6/l

0.46

246

1693

Colon adenocarcinoma, excluding all cancers (controls excluding all cancers)

291

2045

1.45

8.06

3.1

2.5

0.31

0.29

e6/l

0.08

286

2000

Blood alcohol or alcohol intoxication level

322

2.20

8.06

3.3

2.3

0.68

0.17

e6/l

1.13

311

Other and unspecified urticaria

435

3260

1.35

8.05

3.0

2.5

0.21

0.27

e6/l

0.61

420

3150

Mental and behavioural disorders due to alcohol, excluding acute intoxication

1189

9999

1.20

7.99

3.1

2.8

0.33

0.27

e6/l

0.90

1162

9767

Pregnancy hypertension

859

6308

1.24

7.97

2.9

2.3

0.25

0.26

e6/l

0.11

823

6024

Other (seronegative) rheumatoid arthritis, wide

470

3571

1.34

7.97

3.1

2.7

0.19

0.30

e6/l

2.22

458

3477

Pacemaker

911

7278

1.23

7.96

3.1

2.9

0.36

0.30

e6/l

0.42

892

7150

Diseases of the myoneural junction and muscle

301

2135

1.44

7.93

3.0

2.8

0.33

0.31

e6/l

0.13

295

2082

Type 1 diabetes, strict (exclude DM2)

202

1318

1.55

7.91

3.8

2.5

0.23

0.18

e6/l

0.33

197

1266

Early lumbar disc prolapse, operated

196

1274

1.56

7.91

2.6

2.4

0.15

0.23

e6/l

0.72

186

1211

Dementia

1146

6626

1.21

7.87

3.2

2.9

0.37

0.29

e6/l

0.86

1126

6511

Alcohol abuse, main dg

371

2726

1.38

7.86

2.7

2.8

0.38

0.26

e6/l

0.66

361

2661

Maternal care for other conditions predominantly related to pregnancy

417

3073

1.35

7.85

2.3

0.35

0.23

e6/l

0.72

397

2921

Congenital malformations and deformations of the musculoskeletal system

184

1176

1.58

7.85

3.2

2.8

0.16

0.22

e6/l

0.62

170

1137

Endometriosis ASRM stages 3,4

501

3845

1.32

7.84

2.8

2.4

0.31

0.27

e6/l

0.26

488

3702

Umbilical hernia

673

5364

1.27

7.83

3.2

2.8

0.23

0.26

e6/l

0.55

662

5235

Effects of foreign body entering through natural orifice

583

4566

1.29

7.83

2.6

2.8

0.14

0.27

e6/l

4.85

570

4446

Ankylosing spondylitis, ICD10

212

1409

1.54

7.80

2.8

0.44

0.26

e6/l

0.54

203

1369

Parodontitis or operation codes

2448

15985

1.13

7.80

3.0

2.7

0.23

0.29

e6/l

2.04

2404

15521

Dental operations, only avohilmo

2152

9660

1.15

7.79

3.1

2.7

0.24

0.33

e6/l

3.00

2097

9394

Left ventricular outflow tract obstruction (LVOTO), broad definition

230

1555

1.51

7.79

3.3

2.9

0.24

0.26

e6/l

0.12

224

1514

Parodontitis

2445

15979

1.13

7.79

3.0

2.7

0.23

0.29

e6/l

2.04

2401

15515

Benign lipomatous neoplasm

736

5930

1.26

7.79

3.1

2.7

0.29

0.28

e6/l

0.07

715

5781

Dental caries 1 and operation codes

2609

11876

1.13

7.75

2.9

2.7

0.26

0.30

e6/l

0.96

2537

11553

Carcinoma in situ of other and unspecified digestive organs

369

2.10

7.74

3.2

2.5

0.13

0.21

e6/l

1.09

360

Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium

630

3212

1.28

7.71

2.6

2.2

0.20

0.22

e6/l

0.30

597

3051

Benign neoplasm: Ascending colon

303

2163

1.43

7.71

3.2

2.5

0.19

0.28

e6/l

1.36

295

2114

Sarcoidosis

321

2313

1.41

7.71

3.8

2.7

0.19

0.29

e6/l

1.55

312

2254

Chronic periodontitis, including avohilmo

2434

15974

1.13

7.71

3.0

2.7

0.23

0.29

e6/l

2.07

2391

15509

Mental and behavioural disorders due to psychoactive substance use

1608

13121

1.16

7.68

3.1

2.8

0.35

0.27

e6/l

1.48

1571

12799

Other and unspecified mood [affective] disorders

148

908

1.66

7.66

3.4

2.6

0.39

0.22

e6/l

0.56

140

871

COPD, hospital admissions 3, with asthma pneumonia sepsis

767

5286

1.25

7.60

4.0

2.9

0.36

0.30

e6/l

0.61

750

5202

LeFortI or BSSRO operation

524

1.88

7.58

1.9

2.5

0.12

0.15

e6/l

0.46

499

Trigger finger

327

2369

1.40

7.58

2.9

2.5

0.23

0.31

e6/l

0.65

318

2306

Candidiasis

304

2177

1.42

7.56

4.0

2.7

0.42

0.27

e6/l

0.80

296

2115

Parodontitis, under 40 years

180

1161

1.57

7.53

3.3

2.4

0.24

0.17

e6/l

0.43

172

1109

Nail disorders

188

1228

1.56

7.52

2.9

2.7

0.42

0.29

e6/l

0.48

177

1193

Type 1 diabetes, strict definition

157

979

1.62

7.51

2.8

2.4

0.19

0.13

e6/l

0.57

151

934

Gingival hyperplasia

477

1.93

7.50

7.1

2.5

0.38

0.21

e6/l

0.38

464

Ulcer of lower limb, not elsewhere classified

359

2650

1.38

7.48

4.4

2.9

0.36

0.30

e6/l

0.33

349

2600

Parodontitis, under 40 years, or operation codes

180

1163

1.57

7.48

3.3

2.4

0.24

0.17

e6/l

0.43

172

1111

Complications predominantly related to the puerperium

526

4090

1.30

7.46

2.3

2.4

0.25

0.24

e6/l

0.02

505

3906

Speech and linguistic disorders, excluding more controls

155

910

1.63

7.45

3.2

2.6

0.33

0.23

e6/l

0.25

148

879

Corneal ulcer

416

3137

1.34

7.44

3.2

2.6

0.23

0.26

e6/l

0.27

408

3040

Parodontitis, under 40 years and operation codes

169

1078

1.59

7.43

3.4

2.4

0.26

0.17

e6/l

0.47

161

1028

Parodontitis, operation under 40 years and operation codes

169

1079

1.59

7.40

3.4

2.4

0.26

0.17

e6/l

0.47

161

1029

Parodontitis and operation codes

2284

15737

1.13

7.39

3.0

2.7

0.23

0.29

e6/l

2.27

2243

15277

Sequelae of injuries, of poisoning and of other consequences of external causes

549

4302

1.29

7.37

3.0

2.7

0.25

0.27

e6/l

0.19

534

4179

KRA_PSY_EATING, excluding more controls

164

1039

1.60

7.33

3.1

2.1

0.32

0.22

e6/l

0.46

157

989

Stomatitis and related lesions

190

1251

1.55

7.33

3.4

2.6

0.33

0.34

e6/l

0.02

181

1212

Abnormal results of function studies

203

1357

1.53

7.32

4.0

2.7

0.26

0.32

e6/l

0.31

198

1317

Benign neoplasm: Small intestine

101

568

1.84

7.32

3.1

2.5

0.19

0.23

e6/l

0.22

101

551

Primary coxarthrosis, bilateral

736

5977

1.25

7.31

3.0

2.8

0.25

0.31

e6/l

0.51

717

5854

Bacterial, viral and other infectious agents

194

1284

1.54

7.30

3.3

2.8

0.17

0.20

e6/l

0.19

188

1244

Acute and transient psychotic disorders

262

1839

1.45

7.30

2.7

2.6

0.34

0.31

e6/l

0.14

256

1776

Other/unspecified rheumatoid arthritis

312

2261

1.40

7.29

3.5

2.7

0.23

0.32

e6/l

1.10

305

2203

Lesion of lateral popliteal nerve

128

770

1.71

7.28

3.2

2.8

0.35

0.26

e6/l

0.48

128

747

Disorders of psychological development

234

1486

1.48

7.28

3.1

2.7

0.24

0.21

e6/l

0.14

226

1437

Multiple myeloma and malignant plasma cell neoplasms

131

795

1.70

7.26

3.1

2.9

0.31

0.32

e6/l

0.05

131

781

Preterm labour and delivery

515

4009

1.30

7.24

2.7

2.4

0.23

0.25

e6/l

0.14

493

3822

Use of galantamine

197

1315

1.54

7.24

2.9

0.66

0.34

e6/l

0.85

192

1291

Squamous cell neoplasms and carcinomas of the skin

342

2522

1.38

7.22

3.6

3.0

0.38

0.31

e6/l

0.37

332

2480

Chronic diseases of tonsils and adenoids

2075

11574

1.14

7.15

2.5

2.6

0.24

0.28

e6/l

0.79

1996

11233

Collagenous colitis

205

1381

1.51

7.13

3.2

2.7

0.33

0.30

e6/l

0.16

195

1341

Developmental endpoint to exclude non autoimmune-cases from E4_HYTHY_AI_STRICT

763

6231

1.24

7.13

3.1

2.6

0.25

0.28

e6/l

0.33

746

6040

Benign neoplasm: Descending colon

160

1023

1.60

7.12

2.7

2.5

0.15

0.31

e6/l

1.52

154

1000

Otalgia

172

1116

1.57

7.12

3.5

2.8

0.12

0.27

e6/l

2.13

165

1079

Amputation of toe

194

1298

1.53

7.06

5.3

2.8

0.35

0.31

e6/l

0.13

189

1274

Benign neoplasm of other and ill-defined parts of digestive system

430

3289

1.33

7.03

3.4

2.8

0.24

0.31

e6/l

0.72

424

3207

Other strabismus

487

3771

1.30

7.03

3.0

2.6

0.25

0.26

e6/l

0.04

478

3647

Other maternal disorders predominantly related to pregnancy

1222

6521

1.19

7.02

2.6

2.3

0.29

0.26

e6/l

0.29

1176

6223

Abnormal involuntary movements

309

2251

1.39

6.99

3.2

2.8

0.18

0.29

e6/l

1.86

299

2186

Diseases of middle ear and mastoid

1410

9950

1.17

6.99

3.1

2.6

0.26

e6/l

0.01

1370

9663

Lichen planus

298

2159

1.40

6.99

2.9

2.7

0.24

0.31

e6/l

0.74

290

2104

Disorders of ocular muscles, binocular movement, accommodation and refraction

1117

9387

1.19

6.98

3.2

2.6

0.25

0.27

e6/l

0.21

1089

9102

Substance abuse

1551

12888

1.16

6.94

3.1

2.8

0.36

0.27

e6/l

1.66

1514

12574

Other/unspecified reactive arthropathies

159

1021

1.59

6.93

3.3

2.9

0.47

0.25

e6/l

0.50

153

991

Dental pulpitis 3

255

1283

1.45

6.90

2.5

0.32

0.25

e6/l

0.28

248

1233

Calcific aortic valvular stenosis

814

6578

1.23

6.89

3.2

3.0

0.30

0.31

e6/l

0.18

796

6464

Calcific aortic valvular stenosis, operated

814

6578

1.23

6.89

3.2

3.0

0.30

0.31

e6/l

0.18

796

6464

Leiomyoma of uterus

1030

4855

1.20

6.88

2.5

2.3

0.22

0.26

e6/l

0.54

988

4628

Other and/or unspecified nontoxic goitre

192

1287

1.52

6.86

2.2

2.6

0.25

0.28

e6/l

0.18

184

1242

5-aminosalicylic acid

488

3803

1.30

6.86

2.8

2.4

0.26

0.27

e6/l

0.08

473

3687

Focal epilepsy, strict definition

467

3621

1.31

6.86

3.0

2.8

0.33

0.27

e6/l

0.29

457

3535

Benign lipomatous neoplasm of other sites/unspecified

201

1360

1.51

6.85

3.5

2.5

0.24

0.28

e6/l

0.15

196

1324

Operations 2 for CAVS

812

6567

1.22

6.82

3.2

3.0

0.30

0.32

e6/l

0.17

794

6453

Calcific aortic valvular stenosis, diagnosis (helper)

812

6567

1.22

6.82

3.2

3.0

0.30

0.32

e6/l

0.17

794

6453

Ingrowing nail

125

760

1.68

6.82

3.5

2.8

0.48

0.24

e6/l

0.73

119

737

Puerperal sepsis

273

1957

1.42

6.79

2.6

2.4

0.28

e6/l

0.02

263

1874

Ganglion

471

3661

1.30

6.77

2.5

0.21

0.28

e6/l

1.06

453

3544

Calculus of urinary tract in diseases classified elsewhere

9.24

6.74

4.2

5.2

0.07

0.12

e6/l

—

Exclusion endpoint for clefts

232

2.28

6.72

4.0

3.2

0.14

0.10

e6/l

0.26

223

Other and unspecified psoriasis

168

1102

1.56

6.70

3.9

2.8

0.35

0.27

e6/l

0.48

162

1076

Recurring oral aphthae, including avohilmo

302

2208

1.39

6.69

3.4

2.8

0.26

e6/l

0.03

291

2150

Mental and behavioural disorders due to alcohol

1369

11518

1.16

6.68

3.0

2.8

0.33

0.26

e6/l

1.18

1339

11250

Tularaemia

196

2.44

6.67

4.1

2.7

0.37

0.15

e6/l

0.47

190

Symptoms and signs involving speech and voice

795

6569

1.22

6.67

3.1

2.7

0.29

0.27

e6/l

0.17

764

6395

Polyarteritis nodosa and related conditions

228

2.32

6.66

4.9

2.5

0.32

0.16

e6/l

0.37

220

Sequelae of other external causes

130

804

1.66

6.66

4.1

2.7

0.19

0.33

e6/l

0.81

125

780

Pleural effusion

419

3222

1.32

6.66

4.1

2.9

0.30

e6/l

0.01

412

3155

Benign neoplasm of major salivary glands

217

1500

1.47

6.65

3.3

2.6

0.20

0.29

e6/l

0.95

209

1457

Bacterial pneumoniae

1047

7847

1.19

6.60

3.5

2.6

0.30

0.27

e6/l

0.33

1024

7670

Calcific aortic valvular stenosis, including rheumatic fever

813

6595

1.22

6.58

3.2

3.0

0.30

0.32

e6/l

0.17

795

6480

Malignant neoplasm of colon

387

2950

1.33

6.56

3.0

2.9

0.31

e6/l

0.00

382

2893

Tooth eruption problems

276

1972

1.40

6.55

3.8

2.5

0.15

0.24

e6/l

1.40

264

1898

Dental pulpitis 2, only avohilmo

2214

10069

1.13

6.53

3.0

2.7

0.27

0.30

e6/l

0.59

2154

9813

Extrapyramidal and movement disorders

926

7783

1.20

6.49

3.1

2.8

0.29

0.30

e6/l

0.10

897

7615

Blepharochalasis

707

5794

1.23

6.48

3.1

2.7

0.19

0.31

e6/l

4.93

682

5656

Lesion of ulnar nerve

322

2392

1.37

6.47

3.0

2.7

0.28

0.30

e6/l

0.07

312

2322

Early onset COPD

572

4591

1.26

6.39

3.7

2.8

0.36

0.30

e6/l

0.53

562

4500

Vitamin B12 deficiency anaemia

282

2059

1.39

6.37

3.6

2.8

0.25

0.32

e6/l

0.60

276

2012

Strabismus

604

4866

1.25

6.36

3.3

2.6

0.25

0.28

e6/l

0.15

593

4719

Torsion of ovary, ovarian pedicle and fallopian tube

244

2.20

6.35

3.4

2.3

0.22

0.36

e6/l

0.46

236

Dependent personality disorder

299

2.09

6.33

3.2

2.4

0.85

0.16

e6/l

0.94

290

Deviated nasal septum

850

7100

1.21

6.33

2.7

2.8

0.21

0.26

e6/l

0.74

829

6946

Bacterial pneumonia, not elsewhere classified

993

7436

1.19

6.32

3.5

2.6

0.30

0.27

e6/l

0.33

971

7266

Dental caries 3, only avohilmo

2539

11653

1.12

6.31

2.9

2.7

0.27

0.30

e6/l

0.62

2461

11360

Specific developmental disorder of motor function

153

2.53

6.30

2.6

3.7

0.10

0.27

e6/l

0.68

147

Malignant neoplasm of intrahepatic ducts, biliary tract and gallbladder, excluding all cancers (controls excluding all cancers)

155

1014

1.57

6.29

3.1

2.5

0.87

0.33

e6/l

1.31

155

992

Pneumonitis due to solids and liquids

215

1503

1.46

6.28

3.9

3.0

0.28

0.32

e6/l

0.24

215

1469

Motor disorders

156

2.52

6.27

2.6

4.1

0.10

0.26

e6/l

0.66

150

Infective dermatitis

281

2056

1.39

6.26

2.8

0.33

0.32

e6/l

0.06

272

2003

Pre-existing hypertension complicating pregnancy, childbirth and the puerperium

155

1013

1.56

6.24

4.4

2.3

0.21

0.23

e6/l

0.11

144

959

Residual foreign body in soft tissue

117

718

1.67

6.20

2.6

2.5

0.19

0.26

e6/l

0.53

112

698

Childhood asthma (age<16), excluding more controls

231

1287

1.44

6.19

2.3

1.8

0.26

0.24

e6/l

0.06

221

1230

Other disorders of eye and adnexa

297

2194

1.37

6.19

2.8

2.7

0.30

0.27

e6/l

0.14

285

2127

Salpingitis and oophoritis

371

2831

1.33

6.19

2.6

2.4

0.46

0.26

e6/l

0.78

362

2707

Algoneurodystrophy

436

1.87

6.13

3.3

2.5

0.12

0.19

e6/l

0.76

414

Hyperosmolality and hypernatraemia

204

2.33

6.11

3.2

2.5

0.27

0.42

e6/l

0.54

198

Focal epilepsy, mode (most common among epilepsy diagnosis)

438

3424

1.29

6.10

3.0

2.8

0.41

0.28

e6/l

0.61

428

3342

Endometriosis of intestine

147

2.53

6.05

2.1

0.08

0.16

e6/l

0.56

142

Dental caries 1

2366

10841

1.12

6.03

3.0

2.7

0.27

0.30

e6/l

0.34

2297

10560

Vascular disorders of the intestines

167

1120

1.52

6.03

3.4

2.8

0.58

0.37

e6/l

0.62

162

1092

Dental caries, including avohilmo

2364

10835

1.12

6.02

3.0

2.7

0.27

0.30

e6/l

0.36

2295

10554

Chalazion

257

1865

1.40

6.02

3.1

2.7

0.15

0.30

e6/l

2.57

251

1814

Childhood asthma (age<16)

231

1296

1.43

5.99

2.3

1.8

0.26

0.24

e6/l

0.06

221

1237

Colonic or urogenital fistula

652

5347

1.23

5.96

2.9

2.7

0.24

0.28

e6/l

0.49

640

5210

Atrophic disorders of skin

303

2261

1.36

5.94

2.8

2.5

0.22

0.29

e6/l

0.82

296

2186

Benign neoplasm: Parotid gland

173

1173

1.50

5.92

3.2

2.5

0.21

0.30

e6/l

0.67

167

1140

Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk

304

2273

1.36

5.91

2.8

2.7

0.27

e6/l

0.00

294

2207

Dental caries 2 and operation codes, only avohilmo

1469

10402

0.87

5.87

2.7

2.8

0.20

0.25

e6/l

1.11

1427

10116

Complications of other internal prosthetic devices, implants and grafts

102

615

1.71

5.86

3.3

2.4

0.26

0.35

e6/l

0.20

102

595

Melanocytic naevi of other and unspecified parts of face

126

799

1.61

5.85

2.8

2.4

0.09

0.23

e6/l

3.52

120

769

Stenosis and insufficiency of lacrimal passages

214

1514

1.44

5.85

3.0

2.6

0.29

0.33

e6/l

0.17

214

1471

Charcot foot

254

2.14

5.84

4.7

2.5

0.96

0.17

e6/l

1.11

248

Nonsuppurative otitis media

495

3403

1.27

5.83

3.4

2.5

0.25

0.29

e6/l

0.34

482

3295

Amputation

264

1938

1.39

5.82

5.0

2.8

0.40

0.30

e6/l

0.45

258

1900

Unspecified fall

1217

10466

1.16

5.81

3.0

2.7

0.39

0.28

e6/l

1.21

1190

10209

Thyroiditis

159

1064

1.52

5.80

2.7

0.13

0.31

e6/l

2.39

149

1032

Early lumbar disc prolapse operation

205

1441

1.44

5.75

2.7

2.4

0.14

0.23

e6/l

0.87

194

1380

Diseases of tongue

152

1011

1.54

5.73

2.2

2.6

0.30

0.35

e6/l

0.13

144

980

Propionic acid derivatives

869

3658

1.20

5.73

2.7

3.1

0.31

0.33

e6/l

0.11

846

3596

Ulcerative colitis (strict definition, require KELA, min 2 HDR)

354

2716

1.32

5.72

3.0

2.6

0.37

0.24

e6/l

0.59

344

2627

Postprocedural musculoskeletal disorders, not elsewhere classified

168

1143

1.50

5.70

3.2

2.8

0.25

0.31

e6/l

0.31

163

1116

Social phobias

155

1034

1.52

5.69

2.9

2.4

0.24

0.18

e6/l

0.13

148

981

Dysplasia of cervi uteri

446

2714

1.28

5.68

2.5

2.2

0.26

0.32

e6/l

0.58

423

2598

Other and unspecified injuries of wrist and hand

499

1.77

5.66

2.5

2.7

0.12

0.16

e6/l

0.44

479

Ankylosing spondylitis, strict definition

102

622

1.68

5.59

2.1

2.7

0.29

0.16

e6/l

0.85

600

Coronary revascularization (ANGIO or CABG)

1279

7768

1.16

5.57

3.4

2.8

0.30

0.28

e6/l

0.17

1261

7625

Chronic iridocyclitis

119

755

1.61

5.57

3.1

2.7

0.15

0.28

e6/l

1.43

114

731

Basal cell carcinoma, including avohilmo, excluding all cancers (controls excluding all cancers)

1187

7071

1.16

5.54

3.4

2.6

0.26

0.30

e6/l

0.49

1163

6882

Chronic gastritis

694

5774

1.21

5.52

2.9

2.7

0.31

0.30

e6/l

0.07

677

5653

Triptan medication for migraine, min. 3 purchases

1197

8198

1.16

5.46

2.4

0.20

0.26

e6/l

1.18

1151

7854

Benign neoplasm: Other and unspecified parts of small intestine

234

2.15

5.45

3.1

2.6

0.26

0.19

e6/l

0.21

224

Herpesviral [herpes simplex] infections

251

1847

1.38

5.44

3.6

2.7

0.33

0.26

e6/l

0.34

242

1788

Aortic valve malfunction, age under 60 years

203

1443

1.43

5.43

3.3

2.9

0.26

0.28

e6/l

0.06

198

1406

Fibroblastic disorders

608

5009

1.23

5.38

2.9

2.8

0.26

0.32

e6/l

0.52

596

4906

Mental retardation, wide definition

590

1.68

5.37

3.1

0.51

0.16

e6/l

1.00

573

Vasomotor and allergic rhinitis

856

7160

1.19

5.37

2.6

0.18

0.27

e6/l

2.43

825

6930

Flatulence and related conditions

126

2.59

5.36

6.8

2.8

0.03

0.13

e6/l

2.36

118

Pre-eclampsia

400

3146

1.28

5.34

2.9

2.3

0.21

0.26

e6/l

0.64

382

3009

Other peripheral vertigo

213

1533

1.41

5.33

2.9

2.8

0.18

0.31

e6/l

1.40

207

1492

Secondary sideroblastic anaemia due to drugs and toxins

13.50

5.33

2.9

3.5

0.78

0.02

e6/l

—

Acne

193

1363

1.43

5.29

3.8

2.4

0.11

0.21

e6/l

2.82

188

1307

Benign neoplasm: Pancreas

422

1.82

5.29

3.5

2.8

0.06

0.23

e6/l

3.44

413

Embedded teeth, including avohilmo

179

1250

1.45

5.25

3.1

2.5

0.19

0.20

e6/l

0.07

172

1202

Anomalies of dental arch relationship, including avohilmo

395

2789

1.28

5.23

3.2

2.6

0.19

0.24

e6/l

0.52

381

2692

Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

226

1649

1.39

5.22

4.2

2.8

0.53

0.30

e6/l

0.64

219

1603

Benign neoplasm: Sigmoid colon

446

3571

1.27

5.21

3.0

2.9

0.37

0.29

e6/l

0.38

435

3497

Dental caries 1, only avohilmo

2406

11136

1.11

5.21

3.0

2.7

0.27

0.30

e6/l

0.47

2334

10856

Evidence of alcohol involvement determined by level of intoxication

134

2.50

5.20

1.9

2.6

0.28

0.14

e6/l

0.48

126

Renal cell carcinoma of kidney, excluding all cancers (controls excluding all cancers)

521

1.72

5.18

3.9

2.5

0.21

0.31

e6/l

0.31

508

Seronegative rheumatoid arthritis

262

1958

1.36

5.16

2.8

2.5

0.24

0.31

e6/l

0.65

256

1900

Acute nasopharyngitis (common cold)

259

1921

1.36

5.13

3.0

2.4

0.17

0.26

e6/l

1.41

251

1868

Injury of muscle and tendon at wrist and hand level

307

2350

1.32

5.12

2.7

2.8

0.18

0.27

e6/l

1.41

299

2297

Cauda equina syndrome

180

2.28

5.10

4.0

2.9

0.05

0.17

e6/l

1.46

174

Bitten or struck by other mammals

219

1594

1.39

5.10

2.8

2.6

0.28

0.27

e6/l

0.05

214

1533

Secondary thrombocytopenia

181

2.27

5.06

4.1

2.8

0.29

0.11

e6/l

0.46

175

Suppurative otitis media, unspecified

360

1.86

5.06

3.8

2.8

0.28

0.24

e6/l

0.15

354

Dermatophytosis

307

2359

1.32

5.02

2.8

0.36

0.30

e6/l

0.31

300

2303

Other/unspecified enthesopathies, not elsewhere classified

201

1448

1.41

5.01

2.7

2.6

0.24

0.32

e6/l

0.55

194

1409

Other and unspecified bullous disorders

163

2.35

4.99

2.4

2.8

0.46

0.18

e6/l

0.65

158

1544

12621

1.13

4.95

3.0

2.8

0.34

0.27

e6/l

1.10

1509

12334

Basal cell carcinoma, excluding all cancers (controls excluding all cancers)

1163

7001

1.15

4.93

3.4

2.5

0.26

0.30

e6/l

0.57

1140

6815

Hodgkin lymphoma

378

1.82

4.92

2.8

2.5

0.39

0.16

e6/l

1.58

367

Pre-eclampsia or poor fetal growth

593

4903

1.21

4.91

2.6

2.4

0.19

0.25

e6/l

1.07

560

4694

Chronic sinusitis

1020

8845

1.16

4.90

3.0

2.6

0.24

0.27

e6/l

0.33

983

8592

Female infertility

570

2888

1.23

4.89

2.3

2.2

0.28

0.32

e6/l

0.26

541

2756

Pre-eclampsia or eclampsia

427

3424

1.26

4.89

2.9

2.3

0.20

0.26

e6/l

0.90

407

3275

Carcinoma in situ of other and unspecified digestive organs

433

1.78

4.88

3.2

2.9

0.13

0.32

e6/l

2.56

424

Panniculitis, unspecified

165

2.31

4.83

4.6

2.5

0.25

0.21

e6/l

0.12

158

Ulcerative colitis (strict definition, require KELA)

361

2844

1.28

4.83

3.0

2.7

0.36

0.24

e6/l

0.56

350

2749

Malignant neoplasm of other and unspecified parts of biliary tract, excluding all cancers (controls excluding all cancers)

288

1.95

4.80

2.3

2.5

1.64

0.23

e6/l

1.34

278

Other inflammation of eyelid

280

2138

1.33

4.79

3.2

2.7

0.27

0.29

e6/l

0.10

272

2079

Single delivery by caesarean section

349

1568

1.30

4.79

2.2

2.4

0.27

0.26

e6/l

0.09

334

1486

Other and unspecified hydrocephalus

282

1.96

4.75

3.6

2.9

0.21

0.24

e6/l

0.15

274

Vascular dementia

216

1536

1.38

4.75

3.7

2.9

0.26

0.36

e6/l

0.89

210

1512

Gestational [pregnancy-induced] hypertension

491

4001

1.23

4.74

2.6

2.3

0.29

0.24

e6/l

0.39

470

3834

Injury of muscle and tendon at hip and thigh level

210

1540

1.38

4.73

2.5

2.8

0.12

0.29

e6/l

3.92

200

1497

Peripheral artery operations in Hilmo

337

2643

1.29

4.72

4.4

2.8

0.37

0.30

e6/l

0.47

330

2593

Other follicular disorders

148

1021

1.47

4.72

3.8

2.7

0.14

0.21

e6/l

0.63

143

991

severe traumatic brain injury, does not include concussion

554

4591

1.22

4.69

3.1

2.9

0.41

0.30

e6/l

0.72

547

4497

Disorders of conjunctiva

2026

15364

1.11

4.67

2.9

2.6

0.23

0.28

e6/l

1.05

1955

14903

Other disorders of patella

368

2918

1.27

4.67

2.7

2.4

0.24

0.25

e6/l

0.06

356

2830

Subjective visual disturbances

533

4402

1.22

4.65

2.8

2.6

0.22

0.29

e6/l

1.10

513

4281

Mixed disorders of conduct and emotions, excluding more controls

199

2.10

4.65

2.6

2.3

0.50

0.25

e6/l

0.44

192

Disorders of refraction and accommodation

558

4609

1.22

4.65

3.0

2.5

0.23

0.27

e6/l

0.30

541

4457

Autism spe, excluding more controls

206

2.09

4.65

2.0

2.3

0.06

0.15

e6/l

1.28

201

COPD, hospital admissions 1, only main diagnosis

943

6957

1.16

4.63

3.8

2.9

0.32

0.31

e6/l

0.12

924

6838

Benign neoplasm: Small intestine

101

648

1.60

4.62

3.1

2.8

0.19

0.32

e6/l

0.63

101

632

Emergency coronary revascularization (for ACS)

1526

9788

1.13

4.60

3.4

2.9

0.31

0.29

e6/l

0.21

1504

9615

Contraceptive management

881

5324

1.17

4.60

2.3

2.5

0.18

0.25

e6/l

1.57

838

5134

Benign neoplasm: Transverse colon

220

1635

1.37

4.58

3.5

2.6

0.21

0.28

e6/l

0.60

214

1599

Fenamates

387

2074

1.27

4.58

2.6

3.0

0.20

0.31

e6/l

1.96

370

2036

Injury of urinary and pelvic organs

309

1.88

4.49

4.8

2.9

0.23

0.20

e6/l

0.13

300

Anaphylactic shock due to adverse effect of correct drug or medication properly administered

171

2.21

4.43

2.9

2.4

0.79

0.11

e6/l

1.30

165

Exposure to smoke, fire and flames

369

1.79

4.43

3.6

3.0

0.28

0.21

e6/l

0.36

359

Rosacea

241

1824

1.34

4.43

3.0

2.7

0.26

0.29

e6/l

0.21

235

1763

Asthma and allergy, excluding more controls

240

1789

1.34

4.43

2.3

2.1

0.29

0.23

e6/l

0.16

229

1717

Benign neoplasm of mouth and pharynx

247

1877

1.33

4.43

2.6

2.8

0.29

0.28

e6/l

0.02

241

1827

Hypersensitivity pneumonitis due to organic dust

268

1.95

4.42

3.4

2.7

0.20

0.21

e6/l

0.03

260

Benign neoplasm: Other and unspecified parts of small intestine

254

1.97

4.41

3.1

3.0

0.26

0.21

e6/l

0.14

244

Other menopausal disorders

521

2468

1.23

4.41

2.4

0.17

0.36

e6/l

4.61

490

2372

Eating disorders

211

1565

1.36

4.39

2.9

2.4

0.28

0.24

e6/l

0.19

204

1498

Asthma and allergy

240

1792

1.33

4.38

2.3

2.1

0.29

0.23

e6/l

0.19

229

1719

Other disorders of breast

242

1835

1.33

4.37

2.4

0.17

0.28

e6/l

1.37

231

1761

Other abnormalities of plasma proteins

241

2.00

4.37

3.4

2.8

0.10

0.31

e6/l

1.96

234

Nummular dermatitis

194

1427

1.38

4.35

2.9

2.8

0.38

0.29

e6/l

0.37

186

1396

Dental caries 1 and operation codes, only avohilmo

610

3651

0.83

4.33

3.0

0.24

0.25

e6/l

0.03

589

3570

Speech and linguistic disorders

161

1099

1.42

4.32

3.2

2.8

0.32

0.20

e6/l

0.33

154

1061

Use of pramipexole

507

4203

1.22

4.32

3.3

2.8

0.20

0.31

e6/l

2.55

494

4103

Arthropathy in Crohn disease

140

2.33

4.32

3.0

0.26

0.12

e6/l

0.79

134

Benign neoplasm: Caecum

245

1870

1.33

4.30

3.1

2.9

0.22

0.29

e6/l

0.56

237

1829

Hepatomegaly and splenomegaly, not elsewhere classified

121

2.43

4.30

4.6

2.4

0.18

0.11

e6/l

0.34

114

Budesonide

279

2165

1.30

4.27

2.4

0.28

e6/l

0.03

270

2095

351

1.79

4.25

2.7

2.6

0.14

e6/l

0.01

339

Lichen sclerosus et atrophicus

201

1492

1.37

4.23

2.4

2.5

0.23

0.29

e6/l

0.45

196

1445

Dental caries 3 and operation codes, only avohilmo

701

4136

0.85

4.23

3.0

2.9

0.24

0.25

e6/l

0.18

677

4042

Traumatic subarachnoid haemorrhage

551

1.62

4.22

3.6

2.9

0.32

0.22

e6/l

0.52

538

Disorders of continuity of bone

190

1399

1.38

4.21

3.1

2.6

0.26

0.27

e6/l

0.03

184

1351

1606

12964

1.11

4.19

3.0

2.8

0.33

0.26

e6/l

1.09

1571

12664

Other secondary gout

3.38

4.17

1.9

3.2

0.68

0.12

e6/l

0.88

Use of amantadine

252

1.94

4.16

5.0

2.9

0.11

0.16

e6/l

0.42

246

Tongue abnormality

136

952

1.46

4.10

2.3

2.7

0.32

e6/l

0.01

128

924

Malignant neoplasm of testis, excluding all cancers (controls excluding all cancers)

224

1.98

4.10

3.8

2.4

0.09

0.16

e6/l

0.91

218

Colorectal adenocarcinoma

495

4119

1.21

4.10

3.3

3.0

0.34

0.29

e6/l

0.44

488

4037

Other intracranial haemorrhages

565

1.60

4.08

3.5

2.7

0.63

0.36

e6/l

0.46

554

Benign mammary dysplasia

288

2260

1.29

4.07

2.5

0.28

0.32

e6/l

0.29

278

2184

Benign neoplasm: Skin of lip

184

2.09

4.06

3.1

2.7

0.10

0.19

e6/l

0.78

179

Vasomotor rhinitis (mode)

160

1156

1.41

4.03

3.3

2.8

0.13

0.32

e6/l

2.32

154

1121

Acute myeloid leukaemia and myelodysplastic syndromes, excluding all cancers (controls excluding all cancers)

575

1.59

4.00

2.8

2.6

0.58

0.31

e6/l

0.44

558

Thyrotoxicosis with diffuse goitre

279

2186

1.29

3.99

2.8

2.5

0.20

0.25

e6/l

0.39

269

2099

UC patients in KELA-register ( KELA 208 prior to 1994, or ICD K51)

383

3114

1.24

3.97

3.0

2.6

0.36

0.24

e6/l

0.63

372

3008

Endocarditis

584

1.58

3.97

4.7

2.7

0.16

0.29

e6/l

1.12

572

Dental pulpitis 3, only avohilmo

220

1212

1.34

3.96

2.3

2.4

0.34

0.26

e6/l

0.28

214

1166

Discitis, unspecified

264

1.89

3.96

3.5

2.6

0.70

0.27

e6/l

1.04

257

Achilles tendinitis

223

1700

1.33

3.94

3.3

2.7

0.24

0.34

e6/l

0.76

210

1644

Nasal polyp

469

3898

1.21

3.93

2.8

0.22

0.27

e6/l

0.58

458

3819

Acute alcohol intoxication, ICD10

445

3679

1.22

3.93

2.7

2.8

0.33

0.27

e6/l

0.33

434

3590

Fracture of forearm

1268

10610

1.12

3.92

2.7

2.6

0.28

e6/l

0.03

1234

10283

Carcinoma in situ of skin of scalp and neck

346

1.77

3.92

5.1

2.7

0.37

0.34

e6/l

0.04

341

Paranoid personality disorder

279

1.85

3.91

3.4

2.5

0.11

0.16

e6/l

0.37

270

Arthropathy in ulcerative colitis

180

2.08

3.90

2.7

2.8

1.07

0.09

e6/l

0.57

172

Other and unspecified paralytic syndromes

215

1.99

3.90

4.2

3.0

0.22

0.12

e6/l

0.80

206

Injury of muscle and tendon at shoulder and upper arm level

874

7644

1.15

3.89

2.8

0.16

0.28

e6/l

4.46

855

7478

Wilms' tumor

109

2.46

3.86

3.8

3.4

0.12

0.27

e6/l

1.13

109

Other benign neoplasms of uterus

112

766

1.49

3.84

3.0

2.4

0.26

0.32

e6/l

0.20

107

741

Certain zoonotic bacterial diseases

289

1.83

3.81

3.8

2.6

0.36

0.24

e6/l

0.25

280

Dislocation, sprain and strain of joint and ligaments of hip

598

1.56

3.81

3.0

2.8

0.20

0.26

e6/l

0.40

580

Other osteochondropathies

153

1108

1.40

3.81

3.4

2.7

0.15

0.22

e6/l

0.85

148

1074

Thyrotoxicosis, other and/or unspecified

408

3355

1.23

3.81

3.0

2.5

0.24

0.26

e6/l

0.22

396

3235

Congenital malformations of genital organs

175

1286

1.37

3.80

2.4

2.7

0.20

0.23

e6/l

0.26

169

1229

Patellar tendinitis

202

1.99

3.80

4.4

2.8

0.17

0.15

e6/l

0.12

195

Hypertrophy of breast in women and men

385

3148

1.23

3.79

2.3

2.5

0.24

0.28

e6/l

0.37

371

3025

Alcohol use disorder, Swedish definition

1445

12103

1.11

3.77

3.0

2.8

0.33

0.27

e6/l

0.96

1414

11827

Systemic sclerosis (FG)

312

1.78

3.75

3.2

2.1

0.15

0.23

e6/l

0.41

296

Parkinson's disease, strict definition

353

2870

1.25

3.75

3.1

2.9

0.27

0.30

e6/l

0.20

344

2818

1286

0.65

3.72

2.3

2.4

0.11

0.21

e6/l

1.32

1220

Fall on and from stairs and steps

564

4790

1.19

3.72

2.9

2.7

0.28

0.29

e6/l

0.16

550

4660

Lichen ruber planus, wide definition including periferal and oral lichen planus

454

3784

1.21

3.72

2.7

0.26

0.30

e6/l

0.30

437

3682

Evidence of alcohol involvement determined by blood alcohol level

212

1.95

3.69

4.3

2.5

1.08

0.16

e6/l

1.26

204

Foreign body entering into or through eye or natural orifice

173

1286

1.36

3.67

2.4

2.8

0.26

0.24

e6/l

0.11

165

1252

Lichen planus, including avohilmo

394

3245

1.23

3.66

2.7

0.28

0.30

e6/l

0.12

379

3160

Benign neoplasm: Descending colon

160

1179

1.38

3.64

2.7

2.8

0.15

0.31

e6/l

1.60

154

1157

Assault

243

1895

1.29

3.63

2.7

2.5

0.37

0.22

e6/l

0.74

236

1828

Need for immunization against other single viral diseases

286

1.80

3.63

11.3

3.0

0.19

0.16

e6/l

0.23

277

Wide developmental disorders, excluding more controls

274

1.80

3.62

2.0

2.9

0.07

0.20

e6/l

1.00

266

Female infertility, associated with anovulation

133

948

1.42

3.61

2.6

2.0

0.19

0.27

e6/l

0.73

125

895

Myelodysplastic syndrome, excluding all cancers (controls excluding all cancers)

431

1.64

3.61

3.0

2.6

0.38

0.32

e6/l

0.18

421

Melanocytic naevi of other and unspecified parts of face

126

892

1.44

3.61

2.8

2.7

0.09

0.29

e6/l

2.53

120

861

Malignant neoplasm of small intestine, excluding all cancers (controls excluding all cancers)

439

1.64

3.60

3.2

2.5

0.37

0.23

e6/l

0.34

426

Parkinson's disease

376

3091

1.23

3.60

3.1

3.0

0.26

0.30

e6/l

0.22

367

3031

Benign neoplasm of breast

229

1776

1.30

3.60

2.2

2.4

0.18

0.27

e6/l

1.38

221

1701

Oesophageal obstruction

607

1.54

3.58

3.0

2.9

0.24

0.40

e6/l

0.75

593

Contusion of toe(s) without damage to nail

309

1.76

3.57

3.2

2.4

0.09

0.15

e6/l

0.67

299

Autoimmune hepatitis

106

2.38

3.57

2.5

2.3

0.08

0.15

e6/l

0.33

100

Other predominantly sexually transmitted diseases, not elsewhere classified

327

2648

1.24

3.56

2.9

2.4

0.24

0.22

e6/l

0.15

314

2530

Allergic urticaria

161

1190

1.37

3.55

3.1

2.7

0.33

0.25

e6/l

0.42

155

1155

Bacterial pneumonia (organism specified)

1138

9266

1.12

3.54

3.5

2.8

0.30

0.28

e6/l

0.16

1113

9058

Non-small cell lung cancer, squamous, helper endpoint

951

0.61

3.54

3.4

3.0

0.60

0.34

e6/l

0.56

934

Non-small cell lung cancer, squamous

951

0.61

3.54

3.4

3.0

0.60

0.34

e6/l

0.56

934

Other and unspecified haemorrhagic conditions

252

1.85

3.53

4.3

3.0

0.35

0.19

e6/l

0.65

244

Burn and corrosion of wrist and hand

504

1.58

3.52

3.4

2.8

0.13

0.18

e6/l

0.42

491

Retained placenta and membranes, without haemorrhage

231

1800

1.30

3.51

2.2

2.5

0.39

0.25

e6/l

0.53

224

1728

Plantar fascial fibromatosis

198

1512

1.32

3.51

2.7

2.4

0.24

0.30

e6/l

0.24

191

1461

Eating disorder

164

1216

1.36

3.50

3.1

2.4

0.32

0.19

e6/l

0.63

157

1158

ILD-related respiratory insufficiency

571

1.55

3.49

5.2

2.8

0.20

0.30

e6/l

0.67

558

Anti-inflammatory and antirheumatic products, non-steroids

834

3659

1.15

3.47

2.7

3.1

0.25

0.33

e6/l

1.29

806

3597

Atopic dermatitis, strict definition with reimbursement

609

5072

1.17

3.47

2.9

2.4

0.19

0.27

e6/l

1.98

588

4889

Benign neoplasm: Ascending colon

303

2447

1.25

3.46

3.2

2.9

0.19

0.30

e6/l

1.84

295

2400

Autism

245

1.83

3.45

2.0

2.6

0.06

0.13

e6/l

1.14

235

Sequelae of injuries of lower limb

191

1455

1.33

3.45

3.0

2.7

0.18

0.29

e6/l

0.88

184

1410

Distal bite

424

1.62

3.45

3.8

2.4

0.21

0.20

e6/l

0.04

412

Malignant neoplasm of bone and articular cartilage, excluding all cancers (controls excluding all cancers)

261

1.82

3.44

4.0

2.4

0.51

0.21

e6/l

0.51

253

Other benign neoplasm of uterus: Other parts/unspecified

605

1.52

3.41

3.1

2.4

0.31

0.29

e6/l

0.04

586

Mixed disorders of conduct and emotions

224

1.86

3.41

2.6

2.4

0.50

0.14

e6/l

0.79

215

Alzheimer disease, excluding more controls

447

2495

1.21

3.40

3.2

2.8

0.49

0.33

e6/l

0.58

439

2455

Other disorders of cornea

195

1494

1.32

3.40

2.9

2.8

0.22

0.30

e6/l

0.63

189

1454

Female infertility, cervigal, vaginal, other or unspecified origin

491

2770

1.19

3.37

2.3

2.2

0.29

0.33

e6/l

0.21

465

2642

Colon adenocarcinoma

291

2349

1.25

3.35

3.1

2.9

0.31

e6/l

0.04

286

2307

Endometriosis ASRM stages 1,2

338

2771

1.23

3.31

2.6

2.4

0.14

0.27

e6/l

3.41

330

2654

COPD-related respiratory insufficiency

293

2375

1.25

3.26

4.4

2.9

0.35

0.30

e6/l

0.29

288

2331

Hodgkin lymphoma, hilmo

427

1.61

3.26

2.8

0.39

0.22

e6/l

1.04

417

Benign neoplasm: Duodenum

365

1.66

3.25

2.9

2.5

0.13

0.22

e6/l

0.76

356

Benign lipomatous neoplasm of other sites/unspecified

201

1558

1.31

3.24

3.5

2.8

0.24

0.30

e6/l

0.25

196

1519

Visual impairment including blindness (binocular or monocular)

148

1099

1.37

3.23

3.1

2.6

0.36

0.32

e6/l

0.16

143

1066

Personal history of malignant neoplasm

475

1.57

3.22

3.0

2.4

0.24

e6/l

0.02

457

Respiratory disorders in diseases classified elsewhere

223

1.87

3.22

5.9

2.8

0.11

0.19

e6/l

0.56

218

Routine general health check-up of defined subpopulation

234

0.34

3.21

2.1

1.8

0.42

0.31

e6/l

—

223

Recurring oral aphthae

102

712

1.46

3.21

3.5

2.7

0.16

0.31

e6/l

1.00

691

Tibial collateral bursitis [Pellegrini-Stieda]

166

2.01

3.19

2.2

2.3

0.08

0.19

e6/l

1.06

160

Superficial injury of neck

253

1.78

3.16

3.8

2.7

0.13

0.16

e6/l

0.15

244

Alcohol-induced chronic pancreatitis

148

1104

1.36

3.15

3.2

2.9

0.25

e6/l

0.01

143

1084

Malignant neoplasm of ovary

649

1.48

3.14

2.3

2.6

0.16

0.35

e6/l

1.13

626

Traumatic ischaemia of muscle

181

1.95

3.14

2.2

2.7

0.99

0.16

e6/l

0.58

173

Autoimmune thyroiditis

239

1.81

3.13

1.8

2.3

0.10

0.16

e6/l

0.36

230

Ovarian dysfunction

131

959

1.38

3.11

2.9

2.3

0.17

0.21

e6/l

0.41

124

911

Volvulus

393

1.62

3.10

3.8

2.9

0.42

0.24

e6/l

0.59

377

Parkinson's disease, including avohilmo

387

3244

1.21

3.08

3.1

3.0

0.27

0.30

e6/l

0.19

378

3180

Other disorders of the musculoskeletal system and connective tissue

317

2606

1.23

3.08

3.3

2.8

0.22

0.31

e6/l

1.13

306

2539

Spontaneous abortion

924

5590

1.13

3.07

2.9

2.3

0.20

0.28

e6/l

1.43

892

5348

Autism spe

240

1.79

3.06

2.0

2.5

0.06

0.13

e6/l

1.10

230

Use of memantine

630

4776

1.16

3.05

3.4

3.0

0.39

0.34

e6/l

0.37

609

4699

Use of other anti-dementia drugs

630

4776

1.16

3.05

3.4

3.0

0.39

0.34

e6/l

0.37

609

4699

Adjustment and management of implanted device

404

3402

1.20

3.04

2.9

2.8

0.30

0.29

e6/l

0.02

397

3336

Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions

3.41

3.03

7.2

2.7

0.03

0.10

e6/l

0.60

Hallux valgus (acquired)

755

4808

1.14

3.03

2.6

0.24

0.31

e6/l

0.83

720

4661

Scoliosis

157

1188

1.34

3.01

3.9

2.6

0.43

0.29

e6/l

0.36

151

1146

Complications of labour and delivery

1273

6423

1.11

3.01

2.4

2.5

0.29

0.28

e6/l

0.09

1222

6147

Neurofibromatosis, type 2

4.55

3.00

1.2

2.3

0.67

0.03

e6/l

—

False labour

584

3168

1.16

3.00

2.3

0.22

0.23

e6/l

0.09

552

3016

Benign neoplasm of middle ear and respiratory system

161

1227

1.33

2.97

3.5

2.5

0.26

0.28

e6/l

0.07

155

1195

Benign neoplasm: Skin of eyelid, including canthus

304

2500

1.23

2.95

2.5

0.25

0.29

e6/l

0.35

296

2426

Hereditary nephropathy, not elsewhere classified

3.04

2.95

5.2

3.6

0.02

0.14

e6/l

1.15

Cerebral palsy

207

1.83

2.93

5.0

2.8

0.07

0.10

e6/l

0.31

199

Small cell lung cancer

428

0.48

2.93

2.0

2.9

0.54

0.34

e6/l

0.46

418

Small cell lung cancer, helper endpoint

428

0.48

2.93

2.0

2.9

0.54

0.34

e6/l

0.46

418

Autoimmune hyperthyroidism

116

843

1.39

2.92

2.6

2.3

0.24

0.26

e6/l

0.10

111

809

Multiple sites

10.53

2.91

4.8

1.7

0.08

0.09

e6/l

—

Benign neoplasm: salivary glands, exclude unknown (D119)

193

1513

1.29

2.90

3.2

2.9

0.20

0.30

e6/l

0.95

185

1475

Tinnitus

508

4378

1.17

2.89

2.3

2.7

0.17

0.29

e6/l

2.74

485

4267

Carcinoma in situ of skin, other sites/unspecified

173

1.93

2.87

4.3

2.6

0.44

0.24

e6/l

0.37

165

Use of eye-antiallergens (taken as indicator of allergic/atopic conjunctivitis)

970

10592

0.90

2.83

2.4

2.5

0.28

e6/l

0.02

919

10224

Drug-induced hypoglycaemia without coma

255

1.74

2.83

5.9

3.1

0.36

0.27

e6/l

0.25

247

Open wound of abdomen, lower back and pelvis

418

1.56

2.83

3.0

2.8

0.12

0.19

e6/l

0.77

403

Congenital malformations of heart and great arteries

247

1934

1.25

2.81

3.2

2.9

0.15

0.25

e6/l

1.73

240

1881

Use of levodopa decarboxylase inhibitor

320

2662

1.22

2.81

3.1

2.9

0.26

0.31

e6/l

0.27

312

2616

Cryoglobulinemia

4.26

2.81

4.3

3.1

0.37

0.02

e6/l

—

Benign neoplasm of major salivary glands

217

1733

1.27

2.81

3.3

2.8

0.20

0.32

e6/l

1.37

209

1688

Dyslexia and other symbolic dysfunctions, not elsewhere classified

2.77

2.80

2.9

3.3

0.05

0.12

e6/l

0.60

Nephropathy induced by other drugs, medicaments and biological substances

4.69

2.79

8.6

3.4

0.01

0.09

e6/l

—

Uterine polyps

164

1264

1.31

2.79

2.5

2.4

0.18

0.38

e6/l

2.03

157

1217

Ulcerative colitis (strict definition, all Crohn cases excluded)

287

2364

1.22

2.76

3.0

2.6

0.40

0.24

e6/l

0.61

278

2288

Benign neoplasm: Parotid gland

173

1349

1.30

2.74

3.2

2.9

0.21

0.31

e6/l

0.84

167

1313

Open bite

609

1.45

2.73

3.8

2.6

0.14

0.13

e6/l

0.01

589

Amyloidosis

304

1.66

2.72

3.7

2.4

0.22

0.34

e6/l

0.66

296

Maternal care for known or suspected fetal abnormality and damage

181

2045

0.78

2.72

2.1

2.4

0.28

0.22

e6/l

0.27

166

1946

Systemic sclerosis

343

1.61

2.72

3.2

2.5

0.15

0.16

e6/l

0.04

330

Supervision of high-risk pregnancy

372

1888

1.20

2.72

2.6

2.2

0.32

0.24

e6/l

0.36

351

1791

Complications following infusion, transfusion and therapeutic injection

251

1.73

2.71

3.0

2.6

0.09

0.16

e6/l

0.90

243

Other benign neoplasms of uterus

112

822

1.38

2.71

3.0

2.6

0.26

0.34

e6/l

0.28

107

802

Allergic contact dermatitis due to drugs in contact with skin

336

1.62

2.70

2.9

2.7

0.16

0.17

e6/l

0.00

325

Other hammer toe(s) (acquired)

362

2864

1.19

2.68

2.9

2.5

0.37

0.34

e6/l

0.13

348

2781

Myopia

228

1840

1.25

2.67

2.3

2.5

0.30

0.23

e6/l

0.29

219

1771

Other coagulation defects

144

1099

1.33

2.67

4.1

2.7

0.06

0.25

e6/l

7.57

139

1058

Benign neoplasm of breast

229

1852

1.25

2.65

2.2

2.5

0.18

0.31

e6/l

1.77

221

1787

Thyrotoxicosis factitia

2.94

2.64

1.8

2.8

0.01

0.15

e6/l

1.28

Benign neoplasm: Skin, unspecified

556

1.46

2.64

3.5

2.4

0.16

0.20

e6/l

0.25

534

Neovascular glaucoma

708

1.41

2.63

4.2

2.6

0.30

0.26

e6/l

0.11

689

Prolonged pregnancy

178

2054

0.79

2.60

1.6

2.4

0.18

0.22

e6/l

0.32

169

1953

Other extrapyramidal and movement disorders in other diseases

494

4289

1.16

2.60

3.2

2.8

0.29

0.30

e6/l

0.05

480

4184

Thyrotoxicosis

521

4539

1.15

2.60

3.2

2.6

0.21

0.28

e6/l

1.16

507

4390

Dislocation, sprain and strain of joints and ligaments of knee

1402

11971

1.09

2.60

2.5

2.6

0.26

e6/l

0.08

1352

11615

Tonsillectomy and adenotomy

1224

7781

1.10

2.57

2.4

2.5

0.27

0.24

e6/l

0.29

1178

7510

Leiomyoma of uterus

1343

6995

1.10

2.56

2.6

2.4

0.29

0.28

e6/l

0.11

1289

6708

Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]

6.07

2.55

3.8

4.0

0.68

0.30

e6/l

—

Psoas tendinitis

2.39

2.55

2.7

2.3

0.01

0.08

e6/l

1.45

Single delivery by forceps and vacuum extractor

253

1255

1.24

2.54

1.9

2.5

0.18

0.23

e6/l

0.73

241

1188

Benign neoplasm of brain and other parts of central nervous system

121

908

1.35

2.54

2.6

2.4

0.29

e6/l

0.00

116

880

Malignant neoplasm of anus and anal canal, excluding all cancers (controls excluding all cancers)

173

1.86

2.54

2.7

0.39

0.19

e6/l

0.49

165

≡ Risteys

FG R12 + FR

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Hyaline casts [#/volume] in Urine by Automated count

Coding

Definition

OMOP mapping QC

Cohort

Year of birth distribution

Age at first measurement

Age at last measurement

Age at start of registry

Duration from first to last measurement

Statistics

Number of measurements over the years

Number of measurements per person

Distribution of lab values

Value range per person

LabWAS