No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
2089 |
4. Check minimum number of eventsNone |
2089 |
5. Include endpointsNone |
2089 |
6. Filter based on genotype QC (FinnGen only) |
1994 |
Control definitions (FinnGen only)
- Control exclude
- N14_UROLITHIASIS
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- N20-N23
- Name in latin
- Urolithiasis viarum urinariarum inferiorum
Calculus of lower urinary tract
based on the number of shared cases.
Similar with more cases:
Similar with less cases:
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 15015 | 2873 | 11922 |
| Only index persons | 12181 | 2461 | 9720 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.28 | 0.08 | 0.33 |
| Only index persons | 0.31 | 0.09 | 0.37 |
| Median age at first event (years) | |||
| Whole population | 65.15 | 55.17 | 67.47 |
| Only index persons | 63.53 | 52.20 | 66.39 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1994 | 356 | 1638 |
| Unadjusted period prevalence (%) | 0.64 | 0.13 | 0.75 |
| Median age at first event (years) | 65.35 | 52.21 | 68.20 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 2089
- Matched controls
- 20890
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
N20.0
ICD-10 Finland
Calculus of kidney
828.1
307.7
403
6
KH1AA
NOMESCO Finland
Urinary tract X-ray examination without contrast
106.4
307.7
202
21
N21.0
ICD-10 Finland
Calculus in bladder
4503599627370496.0
307.7
1429
*
KH1AD
NOMESCO Finland
CT of urinary organs
24.9
307.7
400
197
N21.1
ICD-10 Finland
Calculus in urethra
2308.9
307.7
362
*
UKC02
NOMESCO Finland
Cystoscopy
9.3
307.7
1274
3004
N20.1
ICD-10 Finland
Calculus of ureter
2562.2
307.7
677
*
KCE02
NOMESCO Finland
Transluminal endoscopic extraction of calculus from bladder
2129.1
307.7
872
7
N20.9
ICD-10 Finland
Urinary calculus, unspecified
176.8
307.7
389
27
KBV02
NOMESCO Finland
Cystoscopic insertion of stent into ureter
21.2
299.3
231
122
KED22
NOMESCO Finland
Transurethral resection of prostate
5.9
262.9
588
1304
R31
ICD-10 Finland
Unspecified haematuria
5.2
255.9
698
1836
KBV12
NOMESCO Finland
Transluminal endoscopic removal of stent from ureter
26.5
219.7
153
62
KBE12
NOMESCO Finland
Transluminal endoscopic extraction of calculus of ureter
2167.2
217.5
207
*
UKB02
NOMESCO Finland
Retrograde ureteroscopy
33.8
207.2
133
42
J01EA01
ATC
trimethoprim; systemic
3.9
176.4
731
2547
KAT00
NOMESCO Finland
Extracorporeal shock wave lithotripsy of pelvis of kidney
1847.3
171.2
164
*
XKD00
NOMESCO Finland
Uroflowmetry
3.5
163.4
896
3714
R33
ICD-10 Finland
Retention of urine
4.1
157.4
542
1645
N21.9
ICD-10 Finland
Calculus of lower urinary tract, unspecified
+∞
155.2
147
*
J01MA02
ATC
ciprofloxacin; systemic
3.2
146.4
1223
6396
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
3.9
141.6
523
1657
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
3.3
136.5
734
2949
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
4.6
128.2
346
866
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
3.5
116.9
510
1782
N30.0
ICD-10 Finland
Acute cystitis
3.8
114.6
422
1319
KAE12
NOMESCO Finland
Retrograde ureteronephroscopic lithotripsy in pelvis of kidney
+∞
99.8
95
*
KBV10
NOMESCO Finland
Removal of stent from ureter
22.6
97.9
72
33
G04CA02
ATC
tamsulosin; oral
2.6
96.9
1114
6416
5921A
ICD-9 Finland
Calculus of kidney and ureter, Calculus of ureter
+∞
95.6
91
*
N40
ICD-10 Finland
Hyperplasia of prostate
2.5
94.7
1077
6152
59203
ICD-8 Finland
Calculus of kidney and ureter, Calculus ureteris
+∞
93.4
89
*
N20.2
ICD-10 Finland
Calculus of kidney with calculus of ureter
819.2
81.0
79
*
N13.3
ICD-10 Finland
Other and unspecified hydronephrosis
6.9
80.5
128
196
KCE00
NOMESCO Finland
Cystolithotomy
808.4
79.9
78
*
KBT00
NOMESCO Finland
Extracorporeal shock wave lithotripsy of ureter
+∞
78.6
75
*
UKA02
NOMESCO Finland
Retrograde ureteronephroscopy
25.6
78.6
55
22
WX320
NOMESCO Finland
Spinalanesthesy
2.4
68.4
666
3430
TKC10
NOMESCO Finland
Percutaneous puncture of bladder
6.5
68.4
114
183
KDV12
NOMESCO Finland
Urethroscopic internal urethrotomy
7.6
67.7
98
135
N30.9
ICD-10 Finland
Cystitis, unspecified
4.2
67.3
189
480
5941A
ICD-9 Finland
Calculus of lower urinary tract, Other calculus in bladder
+∞
63.9
61
*
KBV00
NOMESCO Finland
Insertion of stent into ureter
16.3
63.4
54
34
J01CA08
ATC
pivmecillinam; oral
2.4
59.4
514
2491
TKC22
NOMESCO Finland
Catheterisation instruction
4.7
59.2
143
322
59400
ICD-8 Finland
Calculus of other parts of urinary system, Urethrae
+∞
58.6
56
*
N21.8
ICD-10 Finland
Other lower urinary tract calculus
+∞
58.6
56
*
KBV15
NOMESCO Finland
Cystoscopic change of ureteral stent
16.4
56.5
48
30
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.1
55.0
743
4304
KA1AE
NOMESCO Finland
Kidney ultrasound examination
4.8
54.6
127
277
TKC20
NOMESCO Finland
Catheterisation of bladder
2.9
54.2
286
1083
KH1BD
NOMESCO Finland
Extensive urinary tract CT examination
9.7
52.6
62
66
KE1BE
NOMESCO Finland
Rectal ultrasound examinaiton of prostata
2.4
50.8
414
1939
J01MA12
ATC
levofloxacin; systemic
2.2
49.6
546
2901
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.4
49.3
395
1834
KDV10
NOMESCO Finland
Internal urethrotomy
5.4
46.2
93
179
U06
ICPC
Haematuria
4.1
45.8
129
327
KH1BT
NOMESCO Finland
Urinary tract cathetrisation with X-ray guidance
7.2
45.5
68
97
SPAT1167
SPAT
Insertion of urinary catheter
3.6
45.3
154
446
5920A
ICD-9 Finland
Calculus of kidney and ureter, Calculus of kidney
+∞
45.0
43
*
KA3EB
NOMESCO Finland
Antegrade pyelography
11.5
43.2
45
40
J01MA06
ATC
norfloxacin; oral
2.5
42.6
296
1282
N35.9
ICD-10 Finland
Urethral stricture, unspecified
5.4
42.3
85
163
U07
ICPC
Urine symptom/complaint other
2.9
41.7
207
754
WX408
NOMESCO Finland
General anesthesy, balanced
2.0
39.7
609
3614
UKD02
NOMESCO Finland
Urethroscopy
9.7
37.8
44
46
KED33
NOMESCO Finland
Transurethral incision of prostate
4.4
37.0
95
224
KED76
NOMESCO Finland
TUVP
6.8
36.6
58
88
59401
ICD-8 Finland
Calculus of other parts of urinary system, Vesicae urinariae
+∞
36.6
35
*
KED52
NOMESCO Finland
Visual laser resection of prostate
4.4
36.4
94
223
59408
ICD-8 Finland
Calculus of other parts of urinary system, Aliae definitae
+∞
35.5
34
*
KDE12
NOMESCO Finland
Urethroscopic extraction of calculus of urethra
+∞
35.5
34
*
JN3AD
NOMESCO Finland
Abdominal CT examination
2.3
34.6
290
1360
KCW96
NOMESCO Finland
Other operations on bladder
9.7
34.2
40
42
WX402
NOMESCO Finland
General anaesthesia
2.0
34.2
433
2386
1530
FHL
Urethrocystoscopy
4.6
33.3
80
179
G04BD12
ATC
mirabegron; oral
2.2
33.2
317
1568
N99.1
ICD-10 Finland
Postprocedural urethral stricture
7.4
33.1
48
66
7327
FHL
Lithotripsy
332.2
33.0
33
*
U29
ICPC
Urinary symptom/complaint other
3.7
32.3
104
290
BBA30
NOMESCO Finland
Excision of lesion of parathyroid gland
8.8
32.0
40
46
KH1LA
NOMESCO Finland
Kinetic X-ray examination of urinary tract with pictures
89.0
31.8
35
*
U95
ICPC
Urinary calculus
+∞
31.3
30
*
UKC05
NOMESCO Finland
Cystoscopy and bladder biopsy
5.1
30.2
64
129
TKD00
NOMESCO Finland
Dilatation of urethra
6.7
29.4
47
72
G04BD08
ATC
solifenacin; oral
2.5
29.3
192
803
KCD02
NOMESCO Finland
Transurethral resection of bladder
3.2
29.0
117
377
N13.2
ICD-10 Finland
Hydronephrosis with renal and ureteral calculous obstruction
104.9
28.7
31
*
N32.0
ICD-10 Finland
Bladder-neck obstruction
5.3
28.5
57
109
Z43.5
ICD-10 Finland
Attention to cystostomy
6.6
28.1
45
69
D41.4
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bladder
3.6
27.4
91
259
N02BE01
ATC
paracetamol; systemic, rectal
2.0
26.9
1778
15521
XJH00
NOMESCO Finland
Transanal ultrasonography
2.1
26.5
263
1315
E21.09
ICD-10 Finland
Other primary hyperparathyroidism
5.9
26.2
47
81
G04CA01
ATC
alfuzosin; oral
1.8
26.0
478
2946
U05
ICPC
Urination problems other
2.5
25.2
160
659
C61
ICD-10 Finland
Malignant neoplasm of prostate
1.8
24.0
403
2411
N30.2
ICD-10 Finland
Other chronic cystitis
9.2
23.9
29
32
U02
ICPC
Urinary frequency/urgency
2.1
23.6
240
1208
U08
ICPC
Urinary retention
3.2
23.6
97
316
G04CB01
ATC
finasteride; oral
1.8
23.3
471
2973
KH1FT
NOMESCO Finland
Exchange of urinary catheter with radiological guidance
7.7
23.0
32
42
N23
ICD-10 Finland
Unspecified renal colic
+∞
23.0
22
*
KH1CD
NOMESCO Finland
Very extensive urinary tract ultrasound examination
5.0
22.8
49
100
KCW02
NOMESCO Finland
Lavation of bladder for coagulated blood
4.1
22.7
63
158
C67.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of bladder
3.1
21.6
91
301
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
1.8
21.4
373
2249
J01MA01
ATC
ofloxacin; systemic
2.1
21.4
224
1139
N12
ICD-10 Finland
Tubulo-interstitial nephritis, not specified as acute or chronic
4.0
21.4
61
156
N31.9
ICD-10 Finland
Neuromuscular dysfunction of bladder, unspecified
5.6
21.4
40
72
ZXD05
NOMESCO Finland
Urgent procedure
1.6
21.3
647
4534
G04AC01, ,
ATC
4.1
21.2
58
144
XKC03
NOMESCO Finland
Water cystometry
3.4
21.1
77
233
R30.0
ICD-10 Finland
Dysuria
3.0
21.1
97
338
N30
ICD-10 Finland
Cystitis
2.6
20.9
120
470
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
2.8
20.4
105
389
XKD06
NOMESCO Finland
Physiologic investigation of micturition
2.8
20.3
106
396
SPAT1262
SPAT
Handing over of treatment supplies
1.7
20.2
425
2702
J01DB01
ATC
cefalexin; oral
1.6
19.9
1596
13862
7179
FHL
Other measure in this category
+∞
19.8
19
*
U13
ICPC
Bladder symptom/complaint other
3.2
19.7
77
244
KCF02
NOMESCO Finland
Transluminal endoscopic removal of foreign body from bladder
29.2
19.6
26
9
KCV12
NOMESCO Finland
Urinary bladder endoscopic botulin therapy
5.8
19.3
35
61
N31.0
ICD-10 Finland
Uninhibited neuropathic bladder, not elsewhere classified
8.4
19.3
25
30
KA1FN
NOMESCO Finland
Isotope renography
7.0
19.1
29
42
ZXE10
NOMESCO Finland
More than one and less than three hours
1.6
19.1
727
5339
N31.2
ICD-10 Finland
Flaccid neuropathic bladder, not elsewhere classified
5.4
19.0
37
69
KAE01
NOMESCO Finland
Nephroscopic nephrolithotomy
+∞
18.8
18
*
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.6
18.7
505
3417
G95.8
ICD-10 Finland
Other specified diseases of spinal cord
17.3
18.7
29
17
G04CA52
ATC
tamsulosin and dutasteride; systemic
1.7
18.6
390
2472
SPAT1263
SPAT
Sampling
1.5
18.5
791
5947
Z3231
NOMESCO Finland
Registered nurse
1.6
17.9
567
3982
7171
FHL
Transurethral removal of ureteral stone
+∞
17.7
17
*
J01XE01
ATC
nitrofurantoin; oral
4.5
17.5
42
94
U01
ICPC
Dysuria/painful urination
2.5
17.3
113
471
J01XX05
ATC
methenamine; oral
6.1
17.3
30
50
R39.1
ICD-10 Finland
Other difficulties with micturition
2.6
17.0
98
385
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.9
17.0
215
1168
ZXE00
NOMESCO Finland
One hour or less
1.5
16.4
734
5538
U71
ICPC
Cystitis/urinary infection other
2.7
16.0
89
344
R32
ICD-10 Finland
Unspecified urinary incontinence
3.3
15.8
59
182
N20
ICD-10 Finland
Calculus of kidney and ureter
60.5
15.8
18
*
C67.9
ICD-10 Finland
Malignant neoplasm: Bladder, unspecified
3.0
15.8
69
234
N39.4
ICD-10 Finland
Other specified urinary incontinence
2.2
15.3
137
655
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.5
15.2
563
4069
204
Kela drug reimbursment
Leukemia lymphatica
3.9
15.0
44
115
WX002
NOMESCO Finland
Sedation and analgesia
1.6
14.6
391
2623
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
2.8
14.5
71
257
M03BX01
ATC
baclofen; systemic
3.4
14.4
51
152
N30.1
ICD-10 Finland
Interstitial cystitis (chronic)
5.2
14.4
29
56
L89
ICD-10 Finland
Decubitus ulcer and pressure area
3.0
14.4
63
214
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.7
13.6
275
1716
KDE00
NOMESCO Finland
Urethrolithotomy
+∞
13.6
13
*
N21
ICD-10 Finland
Calculus of lower urinary tract
+∞
13.6
13
*
KBE22
NOMESCO Finland
Transluminal endoscopic dislodgement of impacted calculus from ureter
+∞
13.6
13
*
R35
ICD-10 Finland
Polyuria
1.9
13.5
183
1015
T19.1
ICD-10 Finland
Foreign body in bladder
34.3
13.5
17
5
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
2.1
13.5
122
586
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.7
13.3
280
1766
XKD03
NOMESCO Finland
Urethral pressure profilometry
3.5
13.1
45
132
G04CB02
ATC
dutasteride; oral
1.7
13.0
289
1850
N28.8
ICD-10 Finland
Other specified disorders of kidney and ureter
19.2
12.9
19
10
KCD05
NOMESCO Finland
Excision of bladder lesion during urinary tract endoscopy with photodynamic diagnosis (PDD)
3.3
12.9
48
148
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.9
12.9
173
957
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.6
12.8
296
1912
SPAT1125
SPAT
Stoma care and guidance
3.3
12.6
48
150
N35.8
ICD-10 Finland
Other urethral stricture
6.0
12.6
22
37
308
Kela drug reimbursment
Alprostadil, sildenafil and combination product containing aviptadil and phentolamine
2.6
12.6
70
271
59201
ICD-8 Finland
Calculus of kidney and ureter, Calculus renis
+∞
12.5
12
*
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
2.0
12.5
147
778
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.9
12.3
152
817
SPAT1053
SPAT
Memory test
1.6
12.3
356
2423
N13.0
ICD-10 Finland
Hydronephrosis with ureteropelvic junction obstruction
5.8
12.3
22
38
G04BD07
ATC
tolterodine; oral
2.2
12.3
100
461
UJF32
NOMESCO Finland
Coloscopy
1.5
12.1
520
3846
B02AA02
ATC
tranexamic acid; systemic
1.8
12.0
184
1061
N02AX02
ATC
tramadol; systemic, rectal
1.4
12.0
844
6825
WZC00
NOMESCO Finland
Treatment plan or consultation
1.4
11.8
624
4795
TPH04
NOMESCO Finland
Cathetrisation of vein
1.5
11.6
437
3145
KCD32
NOMESCO Finland
Cystoscopic destruction of tumour of bladder
3.4
11.5
40
118
5942A
ICD-9 Finland
Calculus of lower urinary tract, Calculus in urethra
+∞
11.5
11
*
N39.9
ICD-10 Finland
Disorder of urinary system, unspecified
3.2
11.4
44
139
WX702
NOMESCO Finland
Supraglottic ventilation device
2.1
11.3
103
496
E21.0
ICD-10 Finland
Primary hyperparathyroidism
3.9
11.3
32
82
G35
ICD-10 Finland
Multiple sclerosis
4.4
11.2
28
65
109
Kela drug reimbursment
Multiple sclerosis
5.6
11.2
21
38
KDE20
NOMESCO Finland
Removal of foreign body from urethra
3.5
11.1
38
111
E83.58
ICD-10 Finland
Idiopathic hypercalciuria
20.1
11.1
16
8
N39.3
ICD-10 Finland
Stress incontinence
2.4
11.0
76
326
WX110
NOMESCO Finland
Infiltration anesthesia
1.4
11.0
1221
10571
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
2.3
10.9
86
391
C10AC01
ATC
colestyramine; oral
2.9
10.9
50
175
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.6
10.9
271
1780
U04
ICPC
Incontinence urine
2.0
10.9
111
559
KCH42
NOMESCO Finland
Transurethral incision or resection of bladder neck
8.3
10.8
23
28
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.5
10.8
322
2204
116
Kela drug reimbursment
Prostate cancer
1.7
10.7
220
1377
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.6
10.7
273
1803
N45.9
ICD-10 Finland
Orchitis, epididymitis and epididymo-orchitis without abscess
2.4
10.7
73
312
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.4
10.6
592
4580
B01AB05
ATC
enoxaparin; parenteral
1.4
10.5
592
4583
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
2.3
10.5
82
372
OAB50, ,
SPAT
2.0
10.5
112
574
N30.8
ICD-10 Finland
Other cystitis
5.4
10.4
20
37
T91.3
ICD-10 Finland
Sequelae of injury of spinal cord
9.6
10.3
20
21
SPAT1172
SPAT
Guidance concerning hydration
2.7
10.2
53
198
G04BD11
ATC
fesoterodine; oral
2.5
10.2
65
269
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
1.8
10.1
167
984
TKC20, ,
SPAT
5.3
10.1
20
38
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.4
10.1
552
4249
N31.8
ICD-10 Finland
Other neuromuscular dysfunction of bladder
5.0
10.0
21
42
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.5
9.9
325
2269
K59.1
ICD-10 Finland
Functional diarrhoea
2.1
9.8
96
476
R03DA05
ATC
aminophylline; systemic, rectal
4.1
9.7
26
64
N03AX12
ATC
[U] gabapentin; oral
1.5
9.7
286
1951
TKE00
NOMESCO Finland
Needle biopsy of prostate
1.8
9.7
146
838
N42.0
ICD-10 Finland
Calculus of prostate
55.3
9.6
11
*
C67.2
ICD-10 Finland
Malignant neoplasm: Lateral wall of bladder
3.1
9.5
38
123
KBE00
NOMESCO Finland
Ureterolithotomy
100.5
9.4
10
*
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.5
9.4
309
2156
N41.0
ICD-10 Finland
Acute prostatitis
2.3
9.3
66
287
M01AB05
ATC
diclofenac; systemic, rectal
1.3
9.3
1155
10052
R50.9
ICD-10 Finland
Fever, unspecified
1.5
9.3
291
2011
8130/2-C67.9
ICD-O-3
Papillary urothelial carcinoma, non-invasive of bladder, NOS
3.6
9.1
29
81
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.3
9.1
867
7256
6000A
ICD-9 Finland
Hyperplasia of prostate[HYPERPLASIA PROSTATAE]
2.4
9.1
58
241
G04BD04
ATC
oxybutynin; oral, transdermal
2.0
9.0
100
519
M54.5
ICD-10 Finland
Low back pain
1.4
8.9
544
4250
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
2.1
8.9
78
372
KA3GB
NOMESCO Finland
Retrograde pyelography
12.6
8.9
15
12
G82.2
ICD-10 Finland
Paraplegia, unspecified
4.9
8.8
19
39
N13.9
ICD-10 Finland
Obstructive and reflux uropathy, unspecified
7.2
8.7
20
28
N02AJ06
ATC
codeine and paracetamol; systemic
1.3
8.7
703
5732
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.3
8.6
928
7881
TPH07
NOMESCO Finland
Cathetrisation of artery
1.6
8.6
235
1574
M54.8
ICD-10 Finland
Other dorsalgia
2.3
8.6
64
285
E21.3
ICD-10 Finland
Hyperparathyroidism, unspecified
4.6
8.6
20
44
SPAT1168
SPAT
Catheterisation training
4.1
8.5
23
57
ZXC14
NOMESCO Finland
Other special laser technic
10.1
8.5
16
16
G04AA01, ,
ATC
4.7
8.4
19
41
KEC00
NOMESCO Finland
Retropubic radical prostatectomy
2.4
8.4
54
226
R10.0
ICD-10 Finland
Acute abdomen
2.3
8.3
58
252
ZXC10
NOMESCO Finland
Use of laser
2.5
8.3
49
197
Z93.5
ICD-10 Finland
Cystostomy status
7.1
8.2
19
27
SPAT1301
SPAT
No procedures
1.4
8.2
571
4545
G82.5
ICD-10 Finland
Tetraplegia, unspecified
14.5
8.2
13
9
I10
ICD-10 Finland
Essential (primary) hypertension
1.3
8.2
1258
11188
R42
ICD-10 Finland
Dizziness and giddiness
1.4
8.2
398
2989
A07EC02
ATC
mesalazine; oral, rectal
2.0
8.2
91
474
A10BJ06
ATC
semaglutide; parenteral
2.0
8.1
85
433
KE1AT
NOMESCO Finland
Biopsy of prostata with ultrasoudnguidance
1.6
8.1
192
1244
1520
FHL
Ureteropyeloscopy
33.5
8.1
10
*
7451
FHL
Transurethral adenoma removal
2.7
8.1
42
158
KH1CB
NOMESCO Finland
Urography with X-ray
17.2
8.1
12
7
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.6
8.1
193
1254
A98
ICPC
Health maint/preventive medicine
1.5
8.0
1794
16862
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
1.7
8.0
145
879
8120/3-C67.9
ICD-O-3
Transitional cell carcinoma, NOS, of bladder, NOS
2.4
8.0
53
225
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.4
7.9
495
3874
U70
ICPC
Pyelonephritis/pyelitis
3.1
7.8
31
100
A03
ICPC
Fever
1.5
7.7
225
1529
D06
ICPC
Abdominal pain localized other
1.8
7.7
116
667
N86
ICPC
Multiple sclerosis
7.4
7.7
17
23
L02BB04
ATC
enzalutamide; oral
2.7
7.6
38
140
SPAT1255
SPAT
Intravenous administration of medicine
1.7
7.6
139
844
M01AE03
ATC
ketoprofen; systemic, rectal
1.3
7.5
667
5486
SPAT1254
SPAT
Administration of medicine
1.5
7.5
278
1983
G04BE03
ATC
sildenafil; oral
2.4
7.5
48
200
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.5
7.5
281
2010
SPAT1249
SPAT
Treatment-related counselling outside office
1.3
7.5
662
5445
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.3
7.5
530
4223
ZX120
NOMESCO Finland
Intravenous
1.6
7.5
179
1164
ZXD10
NOMESCO Finland
Scheduled procedure
1.3
7.4
676
5580
7172
FHL
Ureterotomy, involves stone removal
80.4
7.4
8
*
KCF00
NOMESCO Finland
Cystotomy and removal of foreign body from bladder
80.4
7.4
8
*
N02AA05
ATC
oxycodone; systemic
1.4
7.4
374
2823
SPAT1138
SPAT
Guidance concerning bowel function
3.0
7.4
32
109
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
7.3
763
6414
59404, ,
ICD-8 Finland
+∞
7.3
7
*
Q05.2
ICD-10 Finland
Lumbar spina bifida with hydrocephalus
+∞
7.3
7
*
KEE02
NOMESCO Finland
Urethroscopic prostatolithotomy
+∞
7.3
7
*
KH1ZT
NOMESCO Finland
Removal of stone or foreign body from uringary tract with radiological guidance
+∞
7.3
7
*
59209
ICD-8 Finland
Calculus of kidney and ureter, Unspecified
+∞
7.3
7
*
163
Kela drug reimbursment
Abiraterone and enzalutamide
2.6
7.3
40
155
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.6
7.3
148
924
J01CA04
ATC
amoxicillin; systemic
1.3
7.2
1430
13038
E11
ICD-10 Finland
Type 2 diabetes mellitus
1.4
7.2
322
2377
N31.1
ICD-10 Finland
Reflex neuropathic bladder, not elsewhere classified
3.7
7.2
22
60
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.3
7.2
524
4189
ZXA05
NOMESCO Finland
Left side
1.4
7.1
458
3591
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
2.1
7.1
67
329
N02
ICD-10 Finland
Recurrent and persistent haematuria
12.1
7.1
12
10
R07.4
ICD-10 Finland
Chest pain, unspecified
1.3
7.0
502
3999
A10BA02
ATC
metformin; oral
1.3
6.9
594
4853
A07EA02
ATC
hydrocortisone; rectal
2.5
6.9
42
171
D01
ICPC
Abdominal pain/cramps general
1.6
6.9
152
968
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.6
6.9
163
1056
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
2.8
6.9
33
119
M01AH01
ATC
celecoxib; oral
1.4
6.9
281
2042
TJF80
NOMESCO Finland
Ostomy education
3.1
6.9
27
87
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.6
6.9
155
994
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.4
6.8
392
3020
JN4AD
NOMESCO Finland
Body CT examination
1.5
6.8
209
1436
G99.2*M47.1
ICD-10 Finland
Spondylogenic compression of spinal cord
3.8
6.8
20
53
P01AB01
ATC
metronidazole; oral, rectal
1.3
6.7
588
4814
WX725
NOMESCO Finland
Noninvasive ventilation
1.8
6.7
95
536
WZC30
NOMESCO Finland
Teaching
1.4
6.7
284
2077
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.3
6.7
745
6296
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
1.8
6.7
94
530
Z25.1
ICD-10 Finland
Need for immunization against influenza
1.8
6.6
94
531
N47
ICD-10 Finland
Redundant prepuce, phimosis and paraphimosis
1.9
6.6
86
473
KCB00
NOMESCO Finland
Biopsy of bladder
5.5
6.6
18
33
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.4
6.5
285
2095
U28
ICPC
Limited function/disability (U)
2.7
6.5
33
123
K50.0
ICD-10 Finland
Crohn disease of small intestine
3.0
6.5
27
90
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.3
6.5
529
4288
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
1.9
6.5
80
433
T90
ICPC
Diabetes non-insulin dependent
1.3
6.5
482
3858
S29
ICPC
Skin symptom/complaint other
1.4
6.5
307
2291
Y84
ICD-10 Finland
Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.2
6.4
25
80
R53
ICD-10 Finland
Malaise and fatigue
1.4
6.4
386
2994
A06AC01
ATC
ispaghula (psylla seeds); oral
1.3
6.4
419
3292
R60.0
ICD-10 Finland
Localized oedema
1.5
6.4
220
1549
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.5
6.3
216
1516
M79.6
ICD-10 Finland
Pain in limb
1.3
6.3
633
5268
T83.0
ICD-10 Finland
Mechanical complication of urinary (indwelling) catheter
6.0
6.3
16
27
KH1AT
NOMESCO Finland
Urinary tract cathetrisation with ultrasound guidance
5.5
6.3
17
31
G82.0
ICD-10 Finland
Flaccid paraplegia
9.3
6.3
12
13
N28.1
ICD-10 Finland
Cyst of kidney
2.5
6.3
37
149
KAE00
NOMESCO Finland
Nephrolithotomy
+∞
6.3
6
*
N06AX21
ATC
duloxetine; oral
1.6
6.2
151
985
KCC00
NOMESCO Finland
Cystectomy
26.8
6.2
8
*
SPAT1260
SPAT
Consultation of another employee
1.4
6.2
294
2195
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.5
6.1
176
1192
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
1.4
6.1
234
1678
ZXA00
NOMESCO Finland
Right side
1.3
6.1
483
3892
PJD44
NOMESCO Finland
Excision of iliac lymph nodes
3.3
6.1
22
67
KF8AE
NOMESCO Finland
Ultrasound examination of scrotum
2.0
6.1
59
293
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
1.7
6.1
97
567
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.7
6.1
115
706
KK1XE
NOMESCO Finland
Other ultrasound examination of retroperitoneal space and genito-urinary tract
12.6
6.1
10
8
L28
ICPC
Limited function/disability (L)
1.4
6.0
330
2519
R30.9
ICD-10 Finland
Painful micturition, unspecified
3.6
6.0
19
53
ZXA10
NOMESCO Finland
Bilateral
1.4
6.0
329
2512
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1580
10674
2.97
100.98
8.7
4.4
554.68
1361.39
e6/l
0.60
56
201
974
5520
2.43
84.18
5.7
3.4
210.35
95.43
e6/l
1.43
821
4374
763
3874
2.53
83.91
3.9
2.7
4.64
3.59
e6/l
2.14
693
3496
1042
6148
2.39
81.39
6.5
3.8
217.72
124.06
e6/l
1.82
854
4616
868
4983
2.27
69.20
5.2
3.3
0.32
0.47
e6/l
2.83
727
3890
1157
7707
2.12
60.66
6.0
3.6
0.00
0.00
estimate
1.15
278
1612
1149
7646
2.12
60.25
8.0
4.7
0.00
0.00
estimate
-0.00
259
1519
1160
7774
2.11
59.36
6.0
3.6
0.00
0.00
estimate
0.50
252
1445
105
185
5.92
57.33
2.1
1.7
5.74
4.62
mmol/24h
1.77
97
166
1134
7733
2.02
53.01
3.2
2.8
—
—
—
0
0
1382
10208
2.05
50.45
5.6
5.3
6.91
6.90
mmol/l
0.10
1332
9654
273
1067
2.79
48.55
5.0
2.9
0.23
0.25
e6/l
0.18
267
1045
909
5989
1.92
44.35
6.6
3.8
—
—
—
0
0
524
2880
2.09
42.75
5.2
3.1
1.65
1.06
e6/l
1.83
343
1677
544
3032
2.07
42.75
4.6
2.9
1.51
0.91
e6/l
2.89
360
1815
1169
8516
1.85
40.13
8.2
7.5
1.21
1.20
mmol/l
4.81
994
7190
735
4696
1.87
37.94
2.9
3.0
2608.04
6629.12
umol/l
2.43
644
4036
1552
12624
1.89
34.60
8.8
7.9
80.00
80.60
u/l
0.19
1474
11877
1822
15690
2.26
34.41
22.0
17.1
27.53
27.90
mg/l
0.18
1590
12819
1056
7761
1.73
32.36
7.1
6.6
1.21
1.20
mmol/l
5.87
970
7065
773
5218
1.76
31.98
2.8
2.6
166.34
59.08
u/l
0.53
722
4819
1168
8847
1.73
31.90
6.4
6.5
11.42
12.69
umol/l
4.82
1111
8418
1174
8964
1.71
30.59
16.9
19.3
1.27
1.39
inr
4.74
356
2615
1862
16471
2.20
28.06
25.3
20.3
139.95
139.61
mmol/l
8.47
1828
16040
1862
16510
2.18
27.25
25.4
20.5
3.99
4.02
mmol/l
3.13
1824
16056
655
4373
1.73
27.21
6.6
3.9
0.00
0.00
estimate
0.11
239
1397
991
7461
1.62
25.39
5.2
5.2
34.30
34.66
g/l
1.13
912
6942
239
1196
2.13
23.91
4.6
4.5
101.05
104.73
ng/l
0.16
213
1045
922
6979
1.57
22.03
4.6
4.1
44.74
60.13
ng/l
1.11
734
5375
747
5436
1.58
20.85
3.2
3.4
2.35
2.34
mmol/l
1.28
650
4722
1847
16660
1.94
20.71
26.2
20.1
89.60
87.72
umol/l
0.93
1847
16651
400
2486
1.75
20.66
6.1
6.5
1.01
1.03
mmol/l
0.73
377
2313
1266
10441
1.54
19.60
6.2
5.3
4.02
3.83
ug/l
0.10
1125
9279
510
3475
1.62
18.34
6.8
4.0
1.02
1.02
kg/l
0.59
75
518
1672
14813
1.64
17.90
21.2
16.2
75.68
75.93
ml/min/173m2
0.17
1451
12333
777
5910
1.50
16.79
2.4
2.1
73.80
76.82
nmol/l
2.31
675
5194
575
4103
1.55
16.74
2.7
2.6
—
—
—
0
0
1825
16623
1.77
16.73
12.3
11.1
27.34
27.23
u/l
0.03
1756
15922
1874
17212
1.86
16.60
31.5
24.8
7.27
6.95
e9/l
3.37
1823
16631
1873
17210
1.85
16.42
31.5
24.8
236.41
234.43
e9/l
0.64
1826
16703
1873
17215
1.85
16.34
31.5
24.7
4.47
4.48
e12/l
0.07
1820
16639
1872
17204
1.85
16.32
31.5
24.9
40.00
40.11
%
0.29
1740
15920
1873
17219
1.85
16.27
31.7
24.9
134.71
135.79
g/l
1.99
1850
16893
1369
11749
1.48
15.47
4.3
4.0
13.94
13.30
mm/h
0.63
1239
10774
231
1327
1.83
15.30
1.6
1.6
—
—
—
0
0
1567
13850
1.53
15.10
4.2
4.2
1.93
2.11
mu/l
1.18
1380
12392
576
4274
1.48
13.42
4.2
4.2
86.12
82.91
%
2.31
565
4184
218
1284
1.78
13.25
3.8
3.6
2.10
1.85
mmol/l
0.44
162
920
226
1350
1.76
13.08
3.9
3.7
5.14
5.13
kpa
0.09
216
1272
1104
9285
1.40
12.65
9.0
8.9
4.68
4.36
e9/l
3.39
968
8090
945
7772
1.39
12.19
6.6
6.1
24.98
25.89
%
1.43
877
7284
928
7645
1.38
11.68
6.3
5.9
59.82
58.57
%
2.02
862
7168
25
52
4.85
11.43
1.9
1.1
155.40
191.82
mmol/24h
1.08
25
52
47
155
3.08
11.34
2.3
1.9
1.59
1.69
u/field
0.05
22
55
998
8357
1.37
11.19
5.1
4.6
22.95
21.93
%
1.45
591
4342
290
1937
1.58
10.84
4.4
3.7
—
—
—
0
0
723
5795
1.38
10.43
4.0
3.9
14.25
9.71
mg/mmol
0.65
538
3875
33
92
3.63
10.37
2.8
1.5
5.18
2.86
u/field
0.45
22
63
740
5975
1.37
10.13
3.4
3.2
0.87
0.80
ug/l
1.04
542
4220
279
1878
1.56
10.05
4.5
3.8
5.68
5.85
kpa
2.19
269
1814
278
1876
1.56
9.90
4.5
3.8
1.50
1.94
mmol/l
1.33
224
1538
405
2957
1.46
9.86
3.2
3.3
0.81
0.82
mmol/l
1.17
373
2773
1664
15293
1.43
9.71
5.2
4.9
6.18
6.12
mmol/l
1.30
1475
13694
421
3106
1.45
9.69
3.1
3.2
2.46
2.45
mmol/l
1.00
369
2728
1241
10912
1.34
9.35
3.4
3.4
14.97
14.93
pmol/l
0.21
1088
9690
1462
13202
1.36
9.06
25.0
20.0
15.78
15.25
%
2.14
1441
12957
665
5367
1.35
8.86
2.3
2.2
178.51
261.71
u/l
1.89
621
5029
635
5095
1.35
8.77
3.1
3.3
34.12
37.07
u/l
0.51
599
4839
421
3168
1.41
8.59
1.9
1.9
—
—
—
0
0
706
5797
1.33
8.24
3.1
3.2
1695.50
1925.29
ng/l
0.57
605
5057
217
1443
1.56
8.21
4.2
4.3
1.23
1.22
mmol/l
3.52
191
1267
220
1471
1.55
8.13
2.7
2.5
30.87
71.04
u/l
0.66
192
1245
252
1738
1.51
8.07
5.8
7.3
1.31
1.44
mmol/l
1.81
246
1696
128
749
1.76
7.98
1.7
1.8
—
—
—
0
0
273
1921
1.48
7.93
2.8
2.8
7.32
10.37
umol/l
2.54
239
1711
228
1545
1.53
7.93
3.7
3.1
4.65
4.48
kpa
0.49
219
1489
472
3668
1.37
7.87
1.9
1.8
1136.12
1178.92
nmol/l
0.41
345
2770
1600
14770
1.36
7.78
7.2
6.4
41.50
40.92
mmol/mol
1.52
1461
13512
56
247
2.30
7.73
6.8
7.2
7.21
7.58
mmol/l
0.34
45
207
136
823
1.70
7.53
1.8
2.0
—
—
—
0
0
1682
15674
1.38
7.50
5.3
5.2
2.52
2.56
mmol/l
0.86
1516
14245
843
7173
1.29
7.37
2.2
2.1
89.79
91.98
pmol/l
0.72
517
3983
213
1463
1.51
6.95
2.8
2.2
232.30
177.00
ug/g
0.78
172
1167
431
3362
1.36
6.93
1.7
1.7
1.28
1.51
mg/l
0.82
341
2619
1641
15293
1.34
6.86
4.9
4.7
4.28
4.37
mmol/l
2.57
1496
14009
83
447
1.89
6.81
2.5
2.1
131.62
129.56
g/l
0.27
64
334
59
281
2.13
6.80
5.0
6.9
12.48
11.81
mg/l
0.49
54
262
677
5656
1.29
6.64
3.5
3.2
8.31
7.89
mmol/l
1.66
552
4693
1108
9847
1.27
6.53
3.4
3.2
51.31
58.82
u/l
2.23
1022
9063
389
3015
1.36
6.48
1.8
2.0
29.97
30.29
s
0.60
380
2920
171
1141
1.54
6.39
1.5
1.5
—
—
—
0
0
1622
15172
1.31
6.03
4.9
4.6
1.32
1.36
mmol/l
5.02
1464
13767
925
8098
1.26
6.01
2.5
2.5
—
—
—
0
0
74
409
1.84
5.66
4.0
3.4
26.50
31.64
mg/l
0.53
48
271
559
4642
1.28
5.58
2.2
2.2
3.23
3.03
mg/l
0.98
465
3940
757
6517
1.25
5.58
3.1
2.9
156.42
176.18
ug/l
1.16
659
5949
470
3836
1.29
5.35
1.9
1.7
25337306.68
28108519.93
pmol/l
0.04
371
3145
141
942
1.53
5.28
2.1
1.9
2.59
2.95
ug/l
0.15
123
821
170
1185
1.47
5.19
1.7
1.7
—
—
—
0
0
1568
14708
1.26
5.04
4.4
4.2
1.36
1.29
mmol/l
2.84
1402
13254
77
453
1.73
4.82
2.5
2.6
16.79
16.19
%
0.55
52
241
514
4334
1.25
4.37
1.6
1.6
18.58
19.39
nmol/l
0.54
424
3707
270
2101
1.33
4.33
4.7
4.8
32.52
32.42
%
0.05
193
1419
117
788
1.51
4.27
4.3
4.1
24.60
24.75
mmol/l
0.22
111
727
231
1760
1.35
4.27
2.0
2.1
11.30
12.69
nmol/l
1.55
201
1533
32
146
2.21
4.22
1.8
1.4
—
—
—
0
0
14
43
3.27
3.91
1.0
1.1
—
—
—
0
0
121
841
1.47
3.82
1.6
1.8
—
—
—
0
0
218
1677
1.33
3.79
2.2
2.2
0.20
0.20
g/l
0.54
192
1547
102
686
1.51
3.78
3.1
3.3
42.44
7336.43
u/ml
1.09
86
582
293
2358
1.28
3.67
3.8
4.1
235.37
244.30
u/l
0.49
276
2222
269
2142
1.29
3.65
7.9
8.0
95.06
95.26
%
0.16
261
2058
240
1886
1.31
3.60
4.4
4.2
4.98
26.97
ug/l
3.00
197
1595
299
2426
1.27
3.50
2.7
2.4
1.72
1.76
%
0.31
262
2150
20
81
2.48
3.46
1.4
1.4
—
—
—
0
0
288
2333
1.27
3.42
7.7
7.7
0.86
1.14
mmol/l
0.53
231
1813
238
1901
1.28
3.17
7.0
7.5
10.57
11.17
mmol/l
0.61
221
1796
56
342
1.65
3.17
2.9
3.8
0.98
1.74
%
1.51
48
301
68
441
1.56
3.03
1.4
1.5
257.58
260.34
ug/g
0.04
37
284
83
563
1.49
3.02
1.9
1.7
—
—
—
0
0
183
1423
1.31
2.99
3.0
2.9
62.47
62.19
ml/min/173m2
0.03
86
601
17
69
2.48
2.96
5.6
2.6
—
—
—
0
0
17
69
2.48
2.96
5.6
2.6
—
—
—
0
0
108
776
1.41
2.92
1.5
1.7
—
—
—
0
0
227
1827
1.27
2.86
2.6
2.5
66.04
67.94
e9/l
0.41
177
1416
55
348
1.60
2.75
1.3
1.5
0.82
0.85
nmol/l
0.10
50
291
351
2978
1.21
2.74
2.8
2.7
11.89
12.61
umol/l
0.89
314
2787
126
941
1.36
2.73
3.9
2.6
1.31
1.16
%
0.99
126
935
282
2341
1.24
2.72
7.6
7.7
5.07
5.08
kpa
0.03
270
2235
282
2341
1.24
2.72
7.6
7.7
12.22
11.80
kpa
0.67
271
2237
41
241
1.72
2.71
1.2
1.2
—
—
—
0
0
123
916
1.36
2.71
3.4
2.6
0.67
0.64
%
0.39
123
911
9
24
3.76
2.67
1.0
1.2
—
—
—
0
0
263
2173
1.24
2.65
1.9
1.8
—
—
—
0
0
9
25
3.61
2.57
1.1
1.2
—
—
—
0
0
65
951
0.67
2.57
2.0
1.8
—
—
—
0
0
70
476
1.49
2.56
3.1
2.9
1.55
1.70
mg/l
0.93
63
422
411
3562
1.19
2.56
4.0
4.1
475.15
740.97
ng/l
0.42
322
3049
82
577
1.44
2.52
1.2
1.2
—
—
—
0
0
10
31
3.24
2.51
1.0
1.1
—
—
—
0
0
261
2173
1.23
2.46
1.9
1.8
—
—
—
0
0
47
296
1.60
2.43
1.1
1.2
—
—
—
0
0
30
167
1.81
2.41
3.2
2.0
7219.15
2214.41
u/l
0.31
13
58
29
160
1.82
2.39
1.3
1.4
—
—
—
0
0
15
64
2.35
2.39
1.3
1.2
—
—
—
0
0
209
1705
1.25
2.38
1.4
1.4
—
—
—
0
0
33
191
1.74
2.34
2.1
2.7
—
—
—
0
0
11
40
2.76
2.27
1.3
1.1
680.67
251.16
pmol/l
—
6
25
39
239
1.64
2.26
1.6
2.0
—
—
—
0
0
321
2752
1.20
2.26
1.2
1.2
1.37
1.91
u/ml
0.53
92
713
7
18
3.90
2.25
10.3
2.4
0.14
0.39
u/field
—
7
18
463
4100
1.17
2.22
1.7
1.6
1.47
1.36
mmol/l
1.43
368
3366
310
2656
1.20
2.20
3.0
2.7
21.95
22.94
%
0.52
258
2277
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
18
88
2.05
2.11
1.1
1.1
—
—
—
0
0
135
1062
1.29
2.10
8.2
9.9
24.13
24.26
mmol/l
0.19
128
1033
53
357
1.50
2.08
1.4
1.4
11.31
8.31
u/l
1.02
45
292
35
214
1.65
2.07
2.6
3.7
60.90
55.67
%
0.68
27
180
258
2189
1.20
2.04
8.3
7.9
—
—
—
0
0
168
1363
1.25
2.04
2.5
2.2
348.24
370.26
nmol/l
0.76
157
1240
19
97
1.97
2.00
2.5
2.0
—
—
—
0
0
15
70
2.15
1.98
1.1
1.1
—
—
—
0
0
320
2784
1.18
1.91
2.8
2.7
2.23
2.23
g/l
0.04
287
2583
19
99
1.93
1.90
2.3
2.4
—
—
—
0
0
298
2588
1.18
1.82
1.5
1.5
2.61
2.75
g/l
0.59
178
1604
12
53
2.27
1.80
3.3
1.7
0.56
1.18
ug/l
1.33
12
48
16
80
2.01
1.80
1.1
1.1
—
—
—
0
0
56
397
1.42
1.74
1.4
1.3
—
—
—
0
0
56
397
1.42
1.74
1.4
1.3
—
—
—
0
0
7
24
2.92
1.72
1.0
1.2
—
—
—
0
0
60
433
1.40
1.70
1.6
1.6
11527.98
16556.33
e6/l
0.74
42
301
45
308
1.47
1.69
1.8
2.0
—
—
—
0
0
6
19
3.16
1.66
1.0
1.2
—
—
—
0
0
159
1317
1.22
1.64
10.2
7.4
24.31
24.41
mmol/l
0.11
154
1256
24
143
1.69
1.61
1.3
1.5
34.80
23.87
u/ml
—
5
31
134
1094
1.24
1.59
9.0
10.8
—
—
—
0
0
7
26
2.70
1.58
4.1
6.3
—
—
—
0
0
16
86
1.87
1.50
1.0
1.1
—
—
—
0
0
253
2206
1.17
1.50
1.3
1.3
72.41
35.10
iu/ml
0.78
66
676
22
131
1.69
1.49
1.4
1.5
—
—
—
0
0
85
665
1.29
1.45
2.9
3.3
4.46
4.41
pmol/l
0.18
75
581
9
38
2.37
1.45
1.1
1.1
—
—
—
0
0
5
16
3.13
1.44
1.0
1.1
—
—
—
0
0
5
16
3.13
1.44
1.0
1.0
—
—
—
0
0
5
16
3.13
1.44
1.2
1.1
—
—
—
0
0
72
554
1.31
1.40
1.0
1.0
—
—
—
0
0
9
40
2.26
1.40
1.1
1.1
—
—
—
0
0
87
687
1.28
1.40
3.5
3.6
50.93
65.36
mg/l
0.68
70
542
18
104
1.74
1.37
2.9
1.5
16.44
16.02
nmol/l
0.09
18
93
213
1851
1.17
1.34
2.7
2.4
6.67
7.41
ug/l
0.26
165
1626
49
359
1.37
1.32
1.4
1.4
—
—
—
0
0
31
209
1.49
1.30
1.4
1.4
—
—
—
0
0
86
686
1.26
1.29
3.5
3.6
41.17
70.86
mg/l
0.80
70
545
31
210
1.48
1.28
1.5
1.4
—
—
—
0
0
21
130
1.62
1.26
1.9
1.4
1.34
1.10
promille
0.30
14
104
62
476
1.31
1.25
2.0
2.1
88.00
88.18
%
0.03
62
462
6
25
2.40
1.24
1.0
1.1
—
—
—
0
0
6
25
2.40
1.24
1.0
1.2
—
—
—
0
0
9
45
2.00
1.23
1.0
1.0
—
—
—
0
0
9
45
2.00
1.23
1.0
1.0
—
—
—
0
0
12
63
1.91
1.22
1.3
1.3
1858.66
132.30
ug/l
—
7
26
58
443
1.32
1.22
1.6
1.6
54.45
15.85
iu/ml
0.31
18
96
34
238
1.44
1.20
1.1
1.1
11.80
26.28
iu/ml
—
5
47
17
101
1.69
1.19
1.8
1.6
—
—
—
0
0
45
332
1.36
1.19
3.4
3.7
56.93
58.66
%
0.28
45
332
147
1255
1.18
1.17
10.0
9.7
94.48
93.79
%
0.92
147
1248
10
50
2.00
1.16
1.0
1.1
—
—
—
0
0
10
50
2.00
1.16
1.1
1.1
—
—
—
0
0
50
377
1.33
1.16
1.4
1.6
—
—
—
0
0
30
207
1.46
1.15
1.5
1.4
—
—
—
0
0
30
207
1.46
1.15
1.5
1.4
—
—
—
0
0
30
208
1.45
1.13
1.5
1.4
—
—
—
0
0
62
485
1.29
1.12
1.5
1.4
—
—
—
0
0
36
260
1.39
1.09
1.4
1.3
30.46
23.89
iu/l
0.52
29
218
24
160
1.51
1.09
1.3
1.4
—
—
—
0
0
5
21
2.38
1.09
1.0
2.3
280.22
227.10
ng/l
—
5
21
82
668
1.24
1.07
1.2
1.2
137.07
131.67
iu/ml
0.04
30
237
44
331
1.34
1.05
1.5
1.4
1129.11
655.81
e6/l
0.23
36
266
44
331
1.34
1.05
1.4
1.4
59.78
33.64
e6/l
0.30
32
256
47
358
1.32
1.04
1.2
1.3
—
—
—
0
0
32
229
1.40
1.03
2.3
2.2
34.00
18.57
mg/l
—
5
53
67
536
1.26
1.03
2.2
2.3
211.98
113.73
ug/min
0.34
32
327
7
34
2.06
1.03
12.6
11.0
5.50
6.26
mmol/l
—
7
34
25
171
1.47
1.02
1.2
1.3
7.43
7.45
mmol/l
0.01
17
145
9
47
1.92
1.02
1.1
1.1
—
—
—
0
0
106
893
1.20
1.01
1.5
1.3
73.16
63.11
au/ml
—
10
50
18
115
1.57
0.99
1.1
1.2
—
—
—
0
0
29
206
1.41
0.98
1.4
1.4
—
—
—
0
0
5
23
2.18
0.98
1.0
1.0
—
—
—
0
0
5
23
2.18
0.98
1.4
1.2
15.68
16.15
u/l
—
5
13
41
310
1.33
0.97
1.4
1.4
—
—
—
0
0
51
398
1.29
0.96
1.3
1.4
—
—
—
0
0
31
224
1.39
0.96
3.3
4.5
295.26
341.75
umol/l
1.22
23
198
18
116
1.56
0.96
1.2
1.3
—
51.00
—
0
10
12
69
1.74
0.96
1.2
1.5
—
—
—
0
0
19
125
1.52
0.94
1.3
1.1
—
57.82
—
0
11
88
737
1.20
0.91
2.4
2.6
—
—
—
0
0
32
237
1.36
0.88
1.7
1.6
—
—
—
0
0
28
203
1.38
0.87
1.7
1.5
66.56
63.77
%
0.15
18
132
114
982
1.17
0.87
2.7
2.4
17.77
20.67
au/ml
—
10
51
144
1265
1.15
0.85
3.2
2.7
11.08
10.83
g/l
0.21
132
1155
89
752
1.19
0.85
1.2
1.3
193.50
272.56
u/ml
0.91
84
690
17
112
1.52
0.85
1.4
1.6
—
—
—
0
0
8
45
1.78
0.84
1.0
1.0
—
—
—
0
0
6
32
1.88
0.81
1.3
1.2
—
—
—
0
0
61
500
1.23
0.80
2.1
2.3
3.41
3.67
g/l
0.83
61
463
24
173
1.39
0.79
1.7
1.3
103388.06
109743.45
e6/l
0.02
18
119
58
475
1.23
0.77
1.4
1.5
—
—
—
0
0
36
278
1.30
0.77
1.0
1.1
—
—
—
0
0
14
91
1.54
0.75
1.2
1.4
—
—
—
0
0
14
91
1.54
0.75
1.2
1.4
—
—
—
0
0
5
24
2.09
0.74
1.2
1.9
—
—
—
0
0
7
38
1.84
0.73
1.7
1.5
89.00
241.58
nmol/24h
—
7
38
36
282
1.28
0.71
1.4
1.2
383.95
282.15
u/ml
0.70
19
164
77
656
1.18
0.70
2.1
1.8
40.01
37.65
u/l
0.47
68
549
21
152
1.39
0.69
1.0
1.0
1.20
2.51
u/ml
—
5
54
17
119
1.43
0.67
2.6
3.6
—
—
—
0
0
36
449
0.80
0.65
1.5
1.7
3.31
3.20
mg/l
0.04
28
339
16
112
1.43
0.63
1.4
1.6
—
—
—
0
0
16
112
1.43
0.63
3.2
3.3
—
—
—
0
0
8
49
1.64
0.62
1.0
1.2
—
—
—
0
0
228
2105
1.09
0.62
1.3
1.2
13.95
11.48
u/ml
0.17
80
780
50
416
1.21
0.61
1.4
1.6
—
—
—
0
0
42
344
1.23
0.60
1.4
1.5
—
—
—
0
0
38
308
1.24
0.59
1.4
1.2
—
—
—
0
0
159
1746
0.90
0.59
1.6
1.7
1.44
1.63
%
3.05
138
1484
35
281
1.25
0.59
1.3
1.5
—
—
—
0
0
91
803
1.14
0.56
1.6
1.4
—
—
—
0
0
5
88
0.57
0.56
1.2
1.6
6.28
8.15
u/l
—
5
76
10
65
1.54
0.55
2.3
1.6
1.94
11.76
nmol/l
—
10
56
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
88
780
1.13
0.52
3.1
2.8
0.38
0.33
u/ml
0.60
47
439
6
96
0.62
0.52
1.2
1.0
—
—
—
0
0
6
40
1.50
0.51
1.5
1.4
—
—
—
0
0
6
40
1.50
0.51
1.3
1.5
14.60
13.85
pmol/l
—
6
33
16
118
1.36
0.50
1.3
1.3
—
—
—
0
0
24
189
1.27
0.49
1.2
1.1
—
—
—
0
0
56
484
1.16
0.48
1.4
1.6
—
—
—
0
0
34
282
1.21
0.46
2.1
1.4
99.29
124.80
u/ml
—
7
53
5
81
0.62
0.45
1.6
1.9
—
—
—
0
0
5
84
0.59
0.45
1.4
1.6
—
—
—
0
0
18
138
1.31
0.45
1.2
1.2
—
—
—
0
0
7
50
1.40
0.45
4.7
2.5
—
—
—
0
0
38
320
1.19
0.45
3.3
3.4
4.75
4.45
e9/l
0.30
38
320
7
51
1.37
0.44
1.3
1.1
—
—
—
0
0
113
1031
1.10
0.43
1.5
1.7
1.51
1.52
g/l
0.08
97
877
47
405
1.16
0.43
1.9
1.6
—
—
—
0
0
183
1707
1.08
0.43
2.4
2.7
66.81
66.23
g/l
0.38
164
1556
27
221
1.22
0.42
1.4
1.5
—
—
—
0
0
27
221
1.22
0.42
1.4
1.5
—
—
—
0
0
47
406
1.16
0.42
1.1
1.2
—
—
—
0
0
12
87
1.38
0.42
1.2
1.2
—
—
—
0
0
25
203
1.23
0.42
1.2
1.7
—
—
—
0
0
59
520
1.14
0.41
1.6
1.6
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
12
160
0.75
0.39
2.1
1.4
—
—
—
0
0
13
97
1.34
0.39
1.3
1.1
—
—
—
0
0
13
97
1.34
0.39
1.3
1.1
—
—
—
0
0
14
182
0.77
0.39
1.1
1.1
—
11.33
—
0
11
0
19
0.00
0.39
0.0
1.0
—
—
—
0
0
33
279
1.19
0.38
1.3
1.6
—
—
—
0
0
75
675
1.12
0.38
3.1
2.6
0.82
1.27
g/l
0.62
60
578
52
457
1.14
0.38
1.6
2.8
25.65
34.53
umol/l
4.16
42
405
65
580
1.12
0.38
1.1
1.3
—
—
—
0
0
47
411
1.15
0.37
1.1
1.2
—
—
—
0
0
66
592
1.12
0.36
2.2
2.5
0.01
0.03
g/l
0.73
55
541
5
79
0.63
0.35
1.6
1.9
—
—
—
0
0
5
79
0.63
0.35
1.6
1.9
—
—
—
0
0
13
99
1.32
0.35
1.3
1.1
—
—
—
0
0
13
99
1.32
0.35
1.3
1.1
—
—
—
0
0
13
99
1.32
0.35
1.3
1.1
—
—
—
0
0
19
153
1.24
0.35
1.0
1.1
—
—
—
0
0
15
117
1.28
0.35
1.3
1.3
—
—
—
0
0
61
547
1.12
0.34
2.3
2.6
0.00
0.00
g/l
-0.00
51
504
39
339
1.15
0.34
1.3
1.2
2.60
8.97
u/ml
—
5
46
20
163
1.23
0.34
2.3
1.4
29.01
23.54
%
0.28
13
102
81
740
1.10
0.33
2.0
2.6
10.16
10.59
g/l
0.38
71
661
6
46
1.31
0.33
1.3
1.3
111.17
111.63
%
—
6
38
26
219
1.19
0.33
1.3
1.6
—
—
—
0
0
6
88
0.68
0.33
1.2
1.5
—
—
—
0
0
49
435
1.13
0.33
1.7
1.7
—
—
—
0
0
37
322
1.15
0.32
1.4
1.6
—
—
—
0
0
37
322
1.15
0.32
1.4
1.6
—
—
—
0
0
86
789
1.09
0.32
2.0
2.5
3.97
3.75
g/l
0.69
76
712
6
47
1.28
0.32
1.5
1.2
0.27
0.30
g/l
—
6
33
30
257
1.17
0.32
1.6
1.7
2.51
4.77
iu/l
—
10
73
86
790
1.09
0.32
2.0
2.5
7.62
7.35
g/l
0.70
76
713
86
790
1.09
0.32
2.0
2.5
—
—
—
0
0
20
165
1.21
0.31
1.4
1.6
—
—
—
0
0
7
52
1.35
0.31
1.0
1.2
—
—
—
0
0
17
139
1.22
0.29
1.1
1.0
—
—
—
0
0
8
109
0.73
0.29
4.1
1.7
—
—
—
0
0
32
279
1.15
0.28
1.4
1.5
—
—
—
0
0
61
555
1.10
0.28
2.3
2.5
0.00
0.00
g/l
-0.00
51
505
17
140
1.22
0.27
2.5
2.2
—
—
—
0
0
13
104
1.25
0.26
4.8
3.4
12.62
13.22
%
2.99
13
104
20
169
1.19
0.26
2.5
2.2
571.82
650.35
ml
0.34
11
102
184
1758
1.05
0.25
2.7
3.0
281.78
250.74
ng/l
0.27
168
1612
13
159
0.82
0.24
1.1
1.1
0.12
2.30
u/ml
—
6
80
40
360
1.11
0.23
1.2
1.2
80.59
46.97
u/l
0.26
34
319
14
115
1.22
0.23
2.3
2.8
42.14
37.24
%
—
7
72
23
199
1.16
0.23
1.4
1.2
1.73
5.22
u/ml
2.27
11
92
5
39
1.28
0.23
1.2
1.3
—
—
—
0
0
66
612
1.08
0.22
2.3
2.5
37.08
37.40
g/l
0.16
56
536
23
200
1.15
0.22
1.1
1.0
—
—
—
0
0
14
116
1.21
0.22
1.4
1.5
—
—
—
0
0
22
191
1.15
0.22
1.2
1.7
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
10
80
1.25
0.20
1.8
1.9
868.70
1225.11
u/ml
—
10
80
78
732
1.07
0.20
2.1
2.6
3.08
2.97
g/l
0.46
68
655
6
49
1.23
0.20
1.0
1.1
1608.67
1473.61
miu/ml
—
6
49
50
462
1.08
0.19
1.4
1.6
—
—
—
0
0
19
165
1.15
0.19
1.4
1.4
—
—
—
0
0
15
175
0.86
0.18
1.9
1.7
—
1176.00
—
0
10
16
137
1.17
0.18
1.1
1.1
—
—
—
0
0
21
185
1.14
0.18
1.1
1.3
288.73
278.77
mosm/kgh2o
0.64
15
132
11
91
1.21
0.17
1.0
1.0
—
—
—
0
0
7
61
1.15
0.17
1.1
1.2
—
—
—
0
0
5
70
0.71
0.16
1.0
1.4
—
—
—
0
0
52
486
1.07
0.16
1.2
1.2
0.24
1.01
u/ml
—
5
44
35
323
1.09
0.14
1.2
1.3
—
—
—
0
0
11
129
0.85
0.14
1.0
1.0
723.80
609.21
ng/l
—
5
76
19
170
1.12
0.13
1.1
1.1
—
—
—
0
0
9
106
0.85
0.13
1.6
2.3
0.29
0.23
e9/l
—
9
95
23
211
1.09
0.11
3.5
3.7
—
—
—
0
0
10
115
0.87
0.10
1.1
1.1
—
—
—
0
0
13
115
1.13
0.10
1.9
1.6
81.85
93.20
umol/l
0.92
13
115
17
154
1.10
0.10
1.2
1.6
—
—
—
0
0
5
45
1.11
0.09
1.8
1.3
10.36
9.47
ug/l
—
5
45
5
45
1.11
0.09
3.4
2.1
—
—
—
0
0
20
184
1.09
0.09
1.4
1.6
—
—
—
0
0
20
184
1.09
0.09
1.4
1.6
—
—
—
0
0
20
184
1.09
0.09
1.4
1.6
—
—
—
0
0
11
124
0.89
0.09
1.5
1.5
—
—
—
0
0
15
136
1.10
0.08
1.6
1.4
153.34
162.81
pmol/l
0.15
15
136
7
64
1.09
0.08
1.0
1.3
34.29
21.69
%
—
7
48
11
98
1.12
0.07
1.0
1.1
—
—
—
0
0
11
98
1.12
0.07
1.0
1.1
—
—
—
0
0
8
74
1.08
0.07
1.8
1.4
—
—
—
0
0
8
77
1.04
0.07
1.4
1.1
—
—
—
0
0
12
108
1.11
0.07
1.3
1.4
—
—
—
0
0
12
108
1.11
0.07
1.3
1.4
—
—
—
0
0
12
108
1.11
0.07
1.3
1.4
—
—
—
0
0
12
108
1.11
0.07
1.3
1.4
—
—
—
0
0
7
82
0.85
0.07
1.1
1.0
—
—
—
0
0
42
438
0.96
0.07
3.2
3.0
0.71
0.86
nmol/l
1.59
29
331
33
346
0.95
0.06
1.4
1.7
—
—
—
0
0
18
191
0.94
0.04
1.5
1.5
—
—
—
0
0
34
328
1.04
0.04
1.1
1.1
—
—
—
0
0
21
200
1.05
0.03
1.5
1.2
1.91
3.92
u/ml
0.76
11
73
31
300
1.03
0.03
1.4
1.4
4965.86
1786.53
e6/l
0.62
22
217
12
112
1.07
0.03
3.5
2.5
—
—
—
0
0
18
188
0.96
0.02
1.2
1.3
17.17
14.59
u/l
0.16
18
176
10
106
0.94
0.01
1.0
1.3
—
—
—
0
0
10
106
0.94
0.01
1.0
1.3
—
—
—
0
0
28
274
1.02
0.00
1.4
1.4
102011.50
93198.75
e6/l
0.05
20
169
29
284
1.02
0.00
1.3
3.1
35.96
59.34
u/ml
0.64
29
271
11
108
1.02
0.00
1.2
1.2
—
—
—
0
0
14
142
0.99
0.00
1.4
1.1
98.79
94.71
%
0.28
14
133
10
103
0.97
0.00
1.3
1.8
—
—
—
0
0
10
103
0.97
0.00
1.3
1.8
—
—
—
0
0
5
55
0.91
0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
2.00
—
0
8
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
1944.33
—
0
6
6
67
0.90
-0.00
1.2
1.0
—
—
—
0
0
7
77
0.91
-0.00
1.1
1.1
117.74
233.23
iu/ml
—
7
77
5
52
0.96
-0.00
1.4
2.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint N14_CALCULOWER and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| N14_CALCULOWER | 1.812 [1.52, 2.16] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.008 |
During the follow-up period (1.1.1998 — 31.12.2019), 398 out of 1853 females with N14_CALCULOWER died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| N14_CALCULOWER | 1.241 [1.11, 1.38] | < 0.001 |
| Birth year | 0.98 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 2580 out of 8052 males with N14_CALCULOWER died.
Mortality risk
Mortality risk for people of age
years, who have N14_CALCULOWER.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.133% | 0.16% |
| 5 | 0.89% | 1.114% |
| 10 | 2.155% | 2.884% |
| 15 | 4.038% | 5.312% |
| 20 | 6.862% | 8.746% |
Relationships between endpoints
↥Index endpoint: N14_CALCULOWER – Calculus of lower urinary tract
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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