🎉 Check out the future of Risteys: FinRegistry + FinnGen Risteys and let us know what you think 🙂

Use of antiglaucoma preparations and miotics

H7_GLAUCOMAMEDICATION

glaucoma: Increased pressure in the eyeball due to obstruction of the outflow of aqueous humor.

Endpoint definition

FinnGen phenotype data

429209 individuals

diagram downward connector

Apply sex-specific rule None

429209

diagram downward connector

Check conditions None

429209

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, registry filters

Medicine purchases: ATC S01EA

1 out of 7 registries used, show all original rules.

2680

diagram downward connector
diagram bullet

Check minimum number of events

Min. number of events 3

2680

diagram downward connector

Include endpoints None

2680

diagram downward connector
diagram bullet diagram downward connector

Remove individuals based on genotype QC

2579

diagram downward connector
H7_GLAUCOMAMEDICATION

Control definitions

Control exclude H7_GLAUCOMA

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 2579 1368 1211
Unadjusted prevalence (%) 0.63 0.59 0.67
Mean age at first event (years) 65.45 64.79 66.20

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.35 [0.95, 1.92] 9.5e-2 665
15 years 0.01 1.02 [0.77, 1.35] 9.0e-1 368
5 years 0.00 1.43 [1.12, 1.83] 4.1e-3 169
1 year 0.00 0.88 [0.54, 1.44] 6.1e-1 19

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: H7_GLAUCOMAMEDICATION – Use of antiglaucoma preparations and miotics
GWS hits: 8

Survival analyses between endpoints

Plot

before Use of antiglaucoma preparations and miotics
after Use of antiglaucoma preparations and miotics

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Use of antiglaucoma preparations and miotics

Endpoint not on priority list, no data to show.