Benign neoplasm of other and unspecified sites

CD2_BENIGN_OTHER_NOS

benign neoplasm: A neoplasm which is characterized by the absence of morphologic features associated with malignancy (severe cytologic atypia, tumor cell necrosis, and high mitotic rate). Benign neoplasms remain confined to the original site of growth and do not metastasize to other anatomic sites.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D36
  • Cause of death: ICD-10 D36

2 out of 7 registries used, show all original rules.

969

4. Check minimum number of events

None

969

5. Include endpoints

1257

6. Filter based on genotype QC (FinnGen only)

1218

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D10-D36
Name in latin
Neoplasmata benigna locis aliis et non specificatis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 9119 5174 3872
Only index persons 7706 4485 3221
Unadjusted period prevalence (%)
Whole population 0.13 0.15 0.11
Only index persons 0.15 0.16 0.12
Median age at first event (years)
Whole population 50.01 50.24 49.59
Only index persons 47.98 48.44 47.33

-FinnGen-

Key figures

All Female Male
Number of individuals 1218 716 502
Unadjusted period prevalence (%) 0.24 0.25 0.23
Median age at first event (years) 49.88 47.79 52.87

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1257
Matched controls
12570
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D36.7
ICD-10 Finland
Benign neoplasm: Other specified sites
5451.7
307.7
395
*
D36.1
ICD-10 Finland
Benign neoplasm: Peripheral nerves and autonomic nervous system
6034.1
307.7
423
*
ACB19
NOMESCO Finland
Excision of lesion of peripheral nerve other or unspecified
72.9
127.3
69
10
22899
ICD-8 Finland
Benign neoplasm of other and unspecified organs and tissues
+∞
116.5
110
*
22550
ICD-8 Finland
Benign neoplasm of brain and other parts of nervous system, Peripheral nerves
+∞
114.3
108
*
D36.0
ICD-10 Finland
Benign neoplasm: Lymph nodes
+∞
99.3
94
*
D36.9
ICD-10 Finland
Benign neoplasm: Benign neoplasm of unspecified site
+∞
77.9
74
*
DHB10
NOMESCO Finland
Excision of lesion of internal nose
33.4
65.2
42
13
2258X
ICD-9 Finland
Benign neoplasm of brain and other parts of nervous system, Other specified sites of nervous system
+∞
62.0
59
*
D48.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Connective and other soft tissue
6.8
39.0
62
95
NDR20
NOMESCO Finland
Incomplete excision of soft tissue tumour of wrist or hand
9.0
32.9
41
47
DHB00
NOMESCO Finland
Excision of lesion of external nose
9.5
30.1
36
39
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
2.8
26.9
153
603
R22.4
ICD-10 Finland
Localized swelling, mass and lump, lower limb
5.0
26.9
59
123
D48.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Peripheral nerves and autonomic nervous system
98.9
26.8
29
*
D33.45
ICD-10 Finland
Benign Schwannom in the nerve root of the spinal cord
52.9
26.3
31
6
DHA10
NOMESCO Finland
Biopsy of cavity of nose
9.1
26.0
32
36
D14.0
ICD-10 Finland
Benign neoplasm: Middle ear, nasal cavity and accessory sinuses
8.4
24.5
32
39
N03AX16
ATC
[U] pregabalin
2.0
22.6
332
1942
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
4.0
20.8
61
160
Q85.09
ICD-10 Finland
Unspecified neurofibromatosis
78.2
20.7
23
*
Q85.00
ICD-10 Finland
Neurofibromatosis, type 1
58.5
19.9
23
*
D48.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Neoplasm of uncertain or unknown behaviour, unspecified
4.7
19.7
46
101
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
6.4
19.3
32
51
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
2.5
18.9
129
554
D21.1
ICD-10 Finland
Benign neoplasm: Connective and other soft tissue of upper limb, including shoulder
6.5
16.7
27
42
2401
FHL
Nerve exploration (includes biopsy and removal of local change)
23.4
16.5
23
10
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
2.5
15.9
108
462
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
2.6
15.7
98
403
R22.1
ICD-10 Finland
Localized swelling, mass and lump, neck
3.1
15.4
65
217
Z31.5
ICD-10 Finland
Genetic counselling
2.8
15.1
77
286
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
15.0
442
3109
R22.3
ICD-10 Finland
Localized swelling, mass and lump, upper limb
4.0
14.9
42
107
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
14.6
334
2198
D23.3
ICD-10 Finland
Benign neoplasm: Skin of other and unspecified parts of face
3.5
13.9
48
141
ACB99
NOMESCO Finland
Other operation for lesion of peripheral nerve: other or unspecified
54.0
13.8
16
*
ZXD10
NOMESCO Finland
Scheduled procedure
1.6
13.5
471
3435
ABB00
NOMESCO Finland
Excision of lesion of spinal canal
141.5
13.5
14
*
ZXE10
NOMESCO Finland
More than one and less than three hours
1.6
13.2
444
3207
S18
ICPC
Laceration/cut
1.6
13.0
556
4237
N03AX12
ATC
[U] gabapentin; oral
1.8
12.9
219
1319
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.2
12.5
113
546
D21.2
ICD-10 Finland
Benign neoplasm: Connective and other soft tissue of lower limb, including hip
17.5
12.5
19
11
9560/0-C72.9
ICD-O-3
Schwannoma, NOS, of nervous system, NOS
+∞
12.5
12
*
Q85.0
ICD-10 Finland
Neurofibromatosis (nonmalignant)
131.3
12.5
13
*
R22.2
ICD-10 Finland
Localized swelling, mass and lump, trunk
3.0
12.0
54
187
ZXA05
NOMESCO Finland
Left side
1.6
11.8
312
2113
9736
FHL
Subcutaneous tumor removal in operating room or anesthesia
5.3
11.6
23
44
D17.2
ICD-10 Finland
Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
3.5
11.3
39
115
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.3
11.1
84
378
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
2.5
11.0
72
303
SPAT1153
SPAT
Removal of sutures
1.6
10.9
379
2734
ZXA00
NOMESCO Finland
Right side
1.6
10.7
330
2315
WX110
NOMESCO Finland
Infiltration anesthesia
1.5
10.6
847
7244
Q85.01
ICD-10 Finland
Neurofibromatosis, type 2
+∞
10.4
10
*
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.6
10.4
262
1748
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
3.4
10.3
37
112
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
3.0
10.3
45
154
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.2
10.2
91
438
N02AX02
ATC
tramadol; systemic, rectal
1.5
10.0
516
4023
A02BC02
ATC
pantoprazole; systemic
1.5
9.9
817
6980
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
9.8
546
4319
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.6
9.7
244
1627
WX302
NOMESCO Finland
Thoracal epidural anesthesy
2.3
9.6
69
304
2899X
ICD-9 Finland
Other diseases of blood and blood-forming organs, Unspecified diseases of blood and blood-forming organs
+∞
9.4
9
*
D48.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bone and articular cartilage
4.4
9.4
23
53
A02BC03
ATC
lansoprazole; oral
1.5
9.2
350
2557
R03AC02
ATC
salbutamol; inhalant
1.4
8.9
646
5335
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
3.8
8.8
26
69
R59.1
ICD-10 Finland
Generalized enlarged lymph nodes
4.2
8.7
23
56
ACB15
NOMESCO Finland
Excision of local lesion of tibial nerve
50.3
8.7
10
*
NK1AT
NOMESCO Finland
Muscle biopsy with ultrasound guidance
16.4
8.6
13
8
D37.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Liver, gallbladder and bile ducts
3.6
8.4
27
76
ABB10
NOMESCO Finland
Resection of lesion of spinal canal
90.7
8.4
9
*
XW3AT
NOMESCO Finland
Biopsy of other superficial organ with ultrasound guidance
7.9
8.4
18
23
2312
FHL
Extirpation or destruction
+∞
8.3
8
*
TPH04
NOMESCO Finland
Cathetrisation of vein
1.6
8.3
251
1741
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.7
8.3
176
1121
R07.4
ICD-10 Finland
Chest pain, unspecified
1.5
8.2
336
2482
R51
ICD-10 Finland
Headache
2.2
8.2
68
318
N02BE01
ATC
paracetamol; systemic, rectal
1.6
8.2
1082
9946
UJF32
NOMESCO Finland
Coloscopy
1.5
8.2
305
2211
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
2.4
8.2
54
229
D11.0
ICD-10 Finland
Benign neoplasm: Parotid gland
3.2
8.1
31
98
S04
ICPC
Lump/swelling localized
1.8
8.0
123
715
SXC05
NOMESCO Finland
Other oral or dental procedure
2.1
7.9
74
363
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.8
7.9
113
643
R51.80
ICD-10 Finland
Headache
1.6
7.9
181
1175
M79.6
ICD-10 Finland
Pain in limb
1.4
7.8
487
3885
A02BC01
ATC
omeprazole; systemic
1.5
7.7
311
2287
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.8
7.7
124
731
N03AF02
ATC
oxcarbazepine; oral
2.6
7.6
43
169
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.6
7.6
221
1519
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.6
7.6
184
1212
XX2RW, ,
NOMESCO Finland
4.3
7.5
19
45
D33.30
ICD-10 Finland
Acoustic neuroma
7.2
7.5
17
24
PJA10
NOMESCO Finland
Exploration of lymph nodes
3.7
7.5
23
63
WZC00
NOMESCO Finland
Treatment plan or consultation
1.4
7.5
403
3129
NK6CT
NOMESCO Finland
Bone biopsy with CT guidance
13.4
7.4
12
9
WX402
NOMESCO Finland
General anaesthesia
1.5
7.4
232
1620
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
2.9
7.4
33
115
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.6
7.3
185
1229
ACB18
NOMESCO Finland
Excision of local lesion of brachial plexus
+∞
7.3
7
*
Q85.1
ICD-10 Finland
Tuberous sclerosis
+∞
7.3
7
*
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
3.2
7.3
28
89
R13
ICD-10 Finland
Dysphagia
1.9
7.3
88
475
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
2.8
7.3
35
127
A02BC05
ATC
esomeprazole; systemic
1.4
7.3
468
3745
XKD00
NOMESCO Finland
Uroflowmetry
1.6
7.2
157
1005
ZXE00
NOMESCO Finland
One hour or less
1.4
7.2
441
3497
L17
ICPC
Foot/toe symptom/complaint
1.4
7.1
323
2425
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.1
7.1
65
317
M01AH05
ATC
etoricoxib; oral
1.4
7.1
715
6146
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.8
7.1
97
545
P01AB01
ATC
metronidazole; oral, rectal
1.4
7.1
459
3672
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.3
7.1
52
232
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
2.6
7.1
41
164
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
7.1
419
3302
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.6
6.9
151
967
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
2.6
6.9
39
154
H02AB06
ATC
prednisolone; systemic
1.4
6.8
542
4474
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.4
6.8
335
2552
GAA31
NOMESCO Finland
Thoracoscopy
16.8
6.7
10
6
SPAT1202
SPAT
Intra-articular injection
2.5
6.7
42
174
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
1.9
6.7
90
503
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
1.7
6.7
115
692
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
3.0
6.7
28
94
JN3AD
NOMESCO Finland
Abdominal CT examination
1.7
6.7
131
817
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
2.0
6.7
69
353
N64.4
ICD-10 Finland
Mastodynia
2.6
6.6
36
140
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.7
6.5
114
690
J02AC01
ATC
fluconazole; systemic
1.4
6.5
432
3461
SPAT1312
SPAT
General health counselling
1.4
6.4
335
2575
A06AC01
ATC
ispaghula (psylla seeds); oral
1.4
6.4
298
2245
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.7
6.4
130
819
D48.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other specified sites
5.5
6.3
17
31
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.7
6.3
115
704
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.6
6.3
137
878
ACB13
NOMESCO Finland
Excision of local lesion of ulnar nerve
+∞
6.3
6
*
D33.9
ICD-10 Finland
Benign neoplasm: Central nervous system, unspecified
26.8
6.2
8
*
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.4
6.2
452
3668
M79.2
ICD-10 Finland
Neuralgia and neuritis, unspecified
2.7
6.2
32
121
NG1CG
NOMESCO Finland
Knee and lower leg extensive MRI examination with high intensity magnet
2.8
6.2
29
104
SPAT1301
SPAT
No procedures
1.4
6.1
343
2665
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.6
6.1
143
932
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.7
6.1
113
694
M01AC06
ATC
meloxicam; systemic, rectal
1.4
6.1
413
3311
NFR20
NOMESCO Finland
Incomplete excision of soft tissue tumour of hip or thigh
8.6
6.1
12
14
J01DB01
ATC
cefalexin; oral
1.4
6.0
971
8878
D38.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Mediastinum
10.1
6.0
11
11
H02AB09
ATC
hydrocortisone; systemic
2.7
6.0
31
117

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
580
4125
1.75
20.58
2.3
2.1
—
—
—
0
0
171
906
2.03
14.95
1.4
1.4
—
—
—
0
0
224
1322
1.84
14.16
1.4
1.3
—
—
—
0
0
608
4802
1.52
11.63
14.7
15.0
1.23
1.26
inr
0.20
165
1392
609
4838
1.50
11.16
2.9
2.6
—
—
—
0
0
644
5177
1.50
11.13
6.2
5.7
0.04
0.04
e9/l
0.66
568
4515
642
5168
1.50
10.95
6.2
5.7
0.57
0.58
e9/l
0.66
565
4504
658
5344
1.49
10.61
6.3
6.0
0.20
0.19
e9/l
0.52
591
4724
886
7649
1.54
10.59
4.6
4.1
11.14
12.22
mm/h
1.57
816
7078
654
5312
1.48
10.50
6.1
5.8
1.81
1.92
e9/l
1.89
586
4726
632
5103
1.48
10.42
6.8
6.8
1.21
1.21
mmol/l
0.12
555
4344
723
6005
1.48
10.27
9.3
9.0
4.00
4.09
e9/l
0.53
642
5286
582
4635
1.48
10.22
6.8
6.0
1.21
1.21
mmol/l
0.36
540
4236
603
4853
1.47
9.94
7.3
6.2
—
—
—
0
0
717
6059
1.43
8.56
5.6
4.8
6.59
6.70
mmol/l
0.67
684
5688
181
1154
1.66
8.50
7.1
8.2
5.20
5.09
kpa
1.00
174
1107
181
1155
1.66
8.47
7.1
8.1
12.74
12.14
kpa
0.71
176
1110
650
5426
1.41
8.15
6.7
6.2
10.77
11.40
umol/l
0.83
619
5174
179
1159
1.63
7.90
7.2
8.1
1.53
1.16
mmol/l
0.65
139
923
400
3079
1.44
7.85
4.1
3.9
7.40
7.40
ph
0.29
63
597
547
4456
1.40
7.78
5.0
4.8
35.42
35.51
g/l
0.14
501
4156
1109
10286
1.66
7.77
17.6
14.3
22.36
24.03
mg/l
0.95
899
8143
348
2627
1.45
7.54
3.7
3.8
90.03
90.64
%
0.17
341
2563
154
974
1.66
7.44
2.8
2.1
353.96
376.31
nmol/l
0.76
142
891
895
7967
1.43
7.37
8.8
7.5
75.78
78.68
u/l
1.05
848
7516
889
7910
1.42
7.29
4.7
4.0
14.87
14.79
pmol/l
0.42
820
7227
1130
10598
1.66
6.75
20.0
16.4
139.75
139.64
mmol/l
0.74
1103
10323
828
7323
1.38
6.70
4.1
3.8
—
—
—
0
0
412
3272
1.39
6.53
2.9
2.5
62.65
59.15
u/l
0.26
382
3035
1131
10625
1.64
6.52
19.9
16.5
3.96
3.97
mmol/l
1.00
1098
10338
102
599
1.76
6.45
3.5
3.5
4.32
4.54
pmol/l
1.38
89
530
588
4947
1.35
6.45
6.2
5.8
56.66
57.32
%
0.70
553
4655
399
3158
1.39
6.43
2.3
2.2
234.44
248.21
u/l
0.08
376
2976
594
5012
1.35
6.36
6.6
6.0
28.09
27.77
%
0.28
560
4713
581
4886
1.35
6.36
6.9
6.3
8.62
8.57
%
0.11
547
4589
1026
9456
1.46
6.27
5.5
4.8
1.86
2.04
mu/l
0.76
942
8676
576
4861
1.34
6.06
6.4
5.9
2.91
2.83
%
0.35
542
4555
439
3559
1.36
6.01
3.5
3.5
2.36
2.35
mmol/l
0.44
386
3157
406
3264
1.36
5.83
2.6
2.4
—
—
—
0
0
109
673
1.68
5.78
6.1
5.7
—
—
—
0
0
555
4705
1.32
5.48
6.5
5.9
0.73
0.67
%
1.57
522
4400
49
243
2.06
5.20
1.5
1.3
12.43
10.90
u/l
0.26
41
193
477
3980
1.32
5.20
3.9
3.7
26.07
44.47
ng/l
1.23
317
2782
129
854
1.57
5.18
4.1
3.3
—
—
—
0
0
315
2483
1.36
5.02
2.3
2.3
—
—
—
0
0
169
1195
1.48
4.99
1.8
1.7
—
—
—
0
0
28
112
2.53
4.90
1.4
1.7
—
—
—
0
0
202
1486
1.43
4.85
2.1
2.1
—
—
—
0
0
791
7111
1.30
4.79
4.9
4.3
—
—
—
0
0
236
1790
1.39
4.75
1.3
1.3
41.67
30.28
iu/ml
0.50
71
588
339
2723
1.34
4.74
5.0
3.9
0.00
0.01
estimate
1.08
109
926
506
4298
1.30
4.71
2.3
2.3
78.23
77.26
nmol/l
0.30
449
3858
293
2308
1.35
4.66
1.8
1.7
1.04
1.17
mg/l
0.43
229
1777
964
8925
1.34
4.63
19.8
17.0
15.10
14.97
%
0.25
952
8775
390
3209
1.31
4.58
3.3
3.1
—
—
—
0
0
288
2275
1.34
4.48
1.3
1.3
1.02
1.67
u/ml
1.19
72
609
97
623
1.60
4.45
1.5
1.3
17.18
40.34
au/ml
—
5
43
143
1009
1.47
4.28
2.1
2.2
0.22
0.21
g/l
0.39
134
944
166
1210
1.43
4.19
2.1
2.3
168.10
126.33
ug/g
0.52
135
964
580
5067
1.27
4.16
5.7
4.9
0.00
0.00
estimate
0.50
111
960
160
1162
1.43
4.12
1.3
1.3
—
—
—
0
0
345
2829
1.30
4.08
4.5
4.2
—
—
—
0
0
405
3395
1.28
4.04
3.7
3.3
33.66
32.76
u/l
0.11
379
3232
579
5072
1.26
4.01
4.5
3.6
0.00
0.00
estimate
0.75
113
1022
95
623
1.57
4.01
9.5
9.6
0.71
0.68
%
0.25
95
618
25
105
2.41
3.99
1.6
1.5
—
—
—
0
0
191
1441
1.38
3.95
1.2
1.2
—
—
—
0
0
95
627
1.56
3.91
9.3
9.5
1.23
1.37
%
0.80
95
622
321
2621
1.30
3.90
6.7
6.6
—
—
—
0
0
751
6795
1.26
3.90
5.2
4.4
648.36
2549.75
e6/l
1.15
11
100
512
4433
1.26
3.88
3.0
2.7
122.47
127.00
ug/l
0.15
469
4090
291
2347
1.31
3.87
4.6
3.6
—
—
—
0
0
186
1414
1.37
3.67
1.4
1.3
487.18
552.43
titre
0.18
39
301
580
5119
1.25
3.65
4.5
3.6
0.03
0.01
estimate
0.34
112
933
64
390
1.68
3.65
3.0
3.4
72.15
10188.20
u/ml
0.83
52
337
342
2838
1.28
3.64
3.1
3.0
0.64
0.46
e6/l
0.35
276
2179
96
646
1.53
3.63
1.3
1.3
139.49
224.90
u/ml
0.71
89
598
26
117
2.25
3.59
1.8
1.3
—
—
nmol/l
—
0
0
180
1371
1.37
3.51
4.2
5.5
1.03
1.03
mmol/l
0.15
168
1261
242
1928
1.32
3.49
1.8
1.7
1135.00
1188.01
nmol/l
0.35
176
1453
55
326
1.72
3.48
1.8
1.6
271.12
303.99
mu/l
0.58
49
294
19
76
2.52
3.39
1.7
2.0
35.24
37.90
%
0.27
19
76
1142
10983
1.43
3.38
12.2
10.4
25.57
26.26
u/l
0.86
1112
10610
313
2592
1.28
3.36
2.5
2.1
2.97
3.01
mg/l
0.13
261
2209
218
1721
1.32
3.35
1.4
1.3
9.73
11.91
u/ml
0.21
91
680
114
810
1.45
3.32
2.6
3.7
83.11
86.18
ng/l
0.13
96
710
470
4084
1.24
3.32
4.3
3.3
6.26
5.82
ph
1.57
29
306
330
2755
1.27
3.31
3.0
3.0
—
—
—
0
0
122
879
1.43
3.30
2.2
2.5
5.65
7.25
ug/l
0.58
111
779
264
2150
1.29
3.22
2.6
2.5
5.72
6.23
e6/l
0.26
236
1955
63
396
1.62
3.22
8.9
4.5
—
—
—
0
0
205
1616
1.32
3.18
2.1
2.4
13.56
13.09
umol/l
0.37
184
1505
1118
10731
1.38
3.18
16.8
13.4
—
—
—
0
0
211
1676
1.31
3.10
3.6
3.4
0.81
0.82
mmol/l
0.52
199
1577
99
695
1.46
3.09
2.9
2.5
26.46
23.21
au/ml
0.15
14
54
746
6851
1.22
2.96
3.3
3.1
49.63
50.11
u/l
0.04
689
6421
46
273
1.71
2.94
2.0
2.1
6053.67
4136.23
u/l
—
9
109
415
3602
1.23
2.88
3.6
3.6
45.23
116.19
e6/l
2.18
316
2584
15
58
2.61
2.88
5.4
6.8
—
—
—
0
0
49
298
1.67
2.87
8.1
3.9
3.95
3.88
mmol/l
0.38
49
293
114
834
1.40
2.86
6.8
8.4
—
—
—
0
0
214
1722
1.29
2.86
2.8
2.7
0.86
1.11
e6/l
1.11
141
987
63
409
1.57
2.85
1.5
1.3
27.21
30.39
iu/l
0.28
50
349
143
1087
1.36
2.84
3.7
4.2
59.75
26.07
ug/l
0.26
116
893
77
523
1.50
2.84
2.5
2.4
—
—
—
0
0
40
231
1.76
2.82
1.3
1.3
1253.15
963.88
e6/l
0.13
34
184
40
231
1.76
2.82
1.2
1.2
5.87
47.92
e6/l
0.93
31
178
98
702
1.43
2.77
2.6
2.1
11.80
12.98
nmol/l
0.75
90
629
1178
11446
1.46
2.76
26.4
21.0
40.23
40.10
%
0.36
1098
10698
245
2018
1.27
2.71
1.4
1.5
2.17
2.45
g/l
1.93
143
1241
153
1184
1.33
2.71
2.7
2.7
10.35
8.23
umol/l
0.39
130
1040
325
2765
1.24
2.71
1.7
1.7
1.36
1.40
mmol/l
0.29
277
2341
1178
11451
1.46
2.70
26.2
20.9
254.11
250.50
e9/l
1.08
1157
11166
6
10
6.02
2.70
1.7
1.2
—
—
—
0
0
269
2245
1.25
2.66
5.1
3.9
1.02
1.02
kg/l
0.19
32
327
1178
11455
1.45
2.65
26.1
20.8
90.85
91.04
fl
0.85
1163
11290
117
872
1.38
2.64
4.8
4.1
0.94
0.97
%
0.05
42
317
1178
11457
1.45
2.63
26.2
20.9
6.53
6.70
e9/l
2.41
1153
11138
1178
11458
1.45
2.62
26.3
20.9
4.48
4.48
e12/l
0.18
1153
11148
50
314
1.62
2.61
1.5
1.5
248.74
284.68
ug/g
0.72
34
192
60
394
1.55
2.61
1.4
1.2
0.18
1.05
u/ml
—
10
31
10
30
3.35
2.60
2.0
1.7
82.56
97.30
nmol/24h
—
10
30
91
652
1.43
2.58
1.2
1.2
—
—
—
0
0
1178
11461
1.44
2.58
26.4
21.0
134.56
135.13
g/l
0.68
1163
11295
55
355
1.57
2.57
7.5
3.8
1.13
1.36
mmol/l
1.93
55
347
107
794
1.38
2.49
1.1
1.2
—
—
—
0
0
1177
11457
1.43
2.49
26.1
20.8
30.19
30.31
pg
1.61
1162
11290
24
123
1.97
2.46
1.9
1.3
—
—
—
0
0
16
70
2.30
2.41
4.6
3.1
43.50
40.79
%
—
8
40
113
851
1.36
2.41
3.2
3.0
126.18
197.50
ng/l
2.81
102
776
7
17
4.13
2.36
1.3
1.1
—
—
—
0
0
25
134
1.88
2.27
1.9
1.3
0.53
0.63
nmol/l
1.22
25
124
81
583
1.42
2.27
1.2
1.2
—
—
—
0
0
310
2670
1.21
2.26
2.4
2.6
2045.19
5825.43
umol/l
1.83
279
2336
238
1995
1.24
2.26
4.3
3.7
163.79
350.19
ng/l
1.59
191
1550
123
949
1.33
2.25
2.9
2.3
37.14
40.16
u/l
0.16
98
800
105
791
1.36
2.25
4.6
4.0
0.58
0.63
%
0.12
31
272
36
217
1.68
2.24
1.4
1.7
—
—
—
0
0
27
150
1.82
2.21
1.6
1.2
—
—
—
0
0
502
4528
1.18
2.18
10.7
9.5
0.00
0.00
e9/l
0.83
424
3741
76
546
1.42
2.17
8.2
11.1
—
—
—
0
0
353
3096
1.19
2.11
3.2
3.1
35.27
89.97
e6/l
1.42
285
2407
231
1947
1.23
2.08
3.0
3.0
2.47
2.45
mmol/l
1.04
200
1733
141
1124
1.29
2.05
2.9
2.6
1.71
1.84
%
1.01
120
1005
86
638
1.37
2.05
1.7
1.7
1.65
1.41
g/l
0.29
73
588
41
263
1.58
2.02
1.2
1.2
600.95
498.01
mg/l
0.36
41
249
1042
10030
1.23
2.02
4.9
4.5
5.94
5.94
mmol/l
0.05
950
9148
34
209
1.64
1.99
1.2
1.3
—
—
—
0
0
104
802
1.32
1.94
2.7
2.8
9.67
10.75
g/l
2.49
95
738
27
157
1.74
1.93
1.4
1.7
0.66
0.86
g/l
0.49
22
122
106
821
1.32
1.92
4.8
4.2
0.13
0.12
%
0.03
31
265
466
4216
1.17
1.90
2.1
2.0
96.98
95.13
pmol/l
0.39
228
2179
35
220
1.61
1.89
4.7
4.1
—
—
—
0
0
992
9521
1.20
1.88
5.9
5.7
39.17
39.88
mmol/mol
1.90
917
8840
340
3000
1.18
1.88
3.0
3.0
854.07
1299.42
ng/l
2.54
283
2556
7
22
3.19
1.88
2.4
1.9
—
—
—
0
0
100
771
1.32
1.87
4.7
4.2
0.00
0.51
%
0.68
23
215
169
1394
1.25
1.87
2.2
2.4
24.25
22.92
%
0.44
136
1187
18
93
1.95
1.85
5.1
4.6
91.25
56.39
u/ml
—
6
26
243
2084
1.21
1.84
3.0
2.8
508.19
540.22
mosm/kgh2o
1.72
208
1812
5
12
4.18
1.82
1.0
1.2
0.01
1.16
u/ml
—
5
12
106
831
1.30
1.78
2.5
2.8
65.55
66.80
g/l
0.95
97
755
52
364
1.45
1.75
1.6
1.6
—
—
—
0
0
6
18
3.34
1.75
2.0
1.6
—
—
—
0
0
28
170
1.66
1.74
2.2
2.9
—
—
—
0
0
5
13
3.86
1.71
3.6
3.4
—
—
—
0
0
11
48
2.30
1.70
1.3
1.3
159.36
176.66
mmol/24h
0.42
11
48
62
452
1.39
1.68
1.3
1.2
—
—
—
0
0
41
276
1.50
1.68
1.3
1.2
1.48
11.51
u/ml
—
5
50
337
2999
1.17
1.67
4.1
3.9
—
—
—
0
0
309
2731
1.17
1.66
1.5
1.4
—
—
—
0
0
17
90
1.90
1.65
1.0
1.2
—
—
—
0
0
278
2445
1.18
1.59
1.6
1.5
20.38
20.90
nmol/l
0.23
234
2082
10
43
2.34
1.59
1.4
1.1
—
66.29
%
—
0
7
163
1365
1.22
1.58
1.7
1.6
—
—
—
0
0
6
20
3.01
1.58
1.0
1.0
—
—
—
0
0
11
50
2.21
1.57
1.1
1.2
—
—
—
0
0
176
1489
1.21
1.55
2.2
2.4
2.36
2.34
g/l
0.21
160
1390
36
241
1.51
1.53
1.2
1.2
4.23
3.77
mmol/l
1.19
36
228
33
217
1.53
1.52
3.3
2.5
18.02
16.09
%
2.00
18
109
9
38
2.38
1.45
3.8
3.1
—
—
—
0
0
42
294
1.44
1.45
1.2
1.2
96.00
80.83
titre
—
5
24
150
1260
1.22
1.43
1.6
1.4
—
—
—
0
0
90
714
1.28
1.42
1.5
1.4
—
—
—
0
0
134
1115
1.23
1.40
1.8
1.6
—
—
—
0
0
90
716
1.28
1.39
1.7
1.4
—
—
—
0
0
40
282
1.43
1.35
1.6
1.3
203.32
226.78
miu/ml
0.19
24
133
104
847
1.25
1.33
3.7
2.7
67.14
71.57
e9/l
0.60
77
650
112
922
1.24
1.31
3.4
3.4
2.04
1.88
mmol/l
0.19
100
755
27
177
1.54
1.29
1.2
1.4
—
—
—
0
0
16
91
1.77
1.29
1.1
1.2
0.23
0.81
u/ml
0.61
11
47
11
55
2.01
1.27
1.3
1.3
—
—
—
0
0
107
880
1.24
1.27
4.6
3.9
—
—
—
0
0
24
154
1.57
1.26
2.1
1.7
—
—
—
0
0
87
701
1.26
1.24
2.2
2.4
—
—
—
0
0
12
215
0.55
1.23
3.2
3.8
15.63
23.74
mg/l
—
6
142
9
45
2.01
1.23
1.1
1.1
126.56
517.05
u/l
—
9
40
44
323
1.38
1.21
1.2
1.2
—
—
—
0
0
37
265
1.41
1.17
1.2
1.3
—
—
—
0
0
10
50
2.01
1.16
1.5
3.4
—
—
—
0
0
20
126
1.60
1.15
1.8
1.5
0.19
0.32
nmol/l
1.29
12
98
1067
10413
1.16
1.15
5.2
4.9
2.75
2.76
mmol/l
0.07
979
9609
341
3719
0.89
1.14
3.0
2.8
—
—
—
0
0
32
225
1.43
1.13
4.4
5.0
2.71
2.75
mmol/l
0.02
22
153
5
21
2.39
1.09
1.2
3.5
—
29.10
—
0
5
40
295
1.37
1.09
2.2
3.2
—
—
—
0
0
113
952
1.21
1.09
3.6
3.5
—
7.36
—
0
5
1048
10228
1.15
1.06
4.6
4.4
4.67
4.68
mmol/l
0.11
969
9494
21
313
0.67
1.06
1.4
1.6
—
—
—
0
0
5
22
2.28
1.03
1.8
1.3
—
—
—
0
0
30
213
1.42
1.02
3.0
2.2
136.71
129.77
g/l
0.76
24
160
40
299
1.35
1.01
1.2
1.2
—
1227.78
—
0
9
0
29
0.00
0.97
0.0
1.1
—
—
—
0
0
0
30
0.00
0.97
0.0
1.0
—
—
—
0
0
7
36
1.95
0.97
1.6
2.9
—
—
—
0
0
23
157
1.47
0.96
1.5
1.2
8.00
6.36
u/ml
0.11
11
67
12
198
0.60
0.96
1.9
1.6
—
—
—
0
0
21
141
1.50
0.95
1.0
1.0
0.14
2.71
u/ml
—
5
55
9
51
1.77
0.94
1.9
2.7
2815.44
978.00
u/ml
—
9
51
52
409
1.28
0.94
1.1
1.1
—
0.92
u/ml
—
0
5
22
316
0.69
0.94
1.5
1.6
—
—
—
0
0
17
109
1.57
0.93
5.9
4.1
—
—
—
0
0
43
330
1.31
0.93
7.4
10.3
—
—
—
0
0
22
315
0.69
0.93
1.4
1.5
—
—
—
0
0
22
315
0.69
0.93
1.4
1.6
—
—
—
0
0
24
167
1.45
0.92
1.1
1.1
0.83
2.49
u/ml
1.09
12
88
20
291
0.68
0.92
1.5
1.6
—
—
—
0
0
21
143
1.48
0.90
2.6
2.7
—
—
—
0
0
19
127
1.50
0.88
1.1
1.2
—
57.11
—
0
7
245
2230
1.12
0.88
1.7
1.7
27692801.56
24093558.57
pmol/l
0.04
195
1847
16
241
0.66
0.88
1.6
1.7
—
—
—
0
0
41
316
1.31
0.87
2.8
3.5
106.24
70.51
mg/l
0.34
35
254
41
316
1.31
0.87
2.8
3.5
48.21
41.97
mg/l
0.15
35
254
16
103
1.56
0.87
1.1
1.2
—
—
—
0
0
6
30
2.00
0.87
1.2
1.2
—
—
—
0
0
36
273
1.33
0.86
4.3
4.5
7.43
7.42
ph
0.45
31
245
12
72
1.67
0.85
1.2
1.2
—
—
—
0
0
21
145
1.46
0.85
1.1
1.0
4.46
6.63
u/ml
—
8
66
79
662
1.21
0.84
4.8
3.8
7.42
7.40
ph
0.85
12
85
80
672
1.20
0.83
4.8
3.8
5.22
5.14
kpa
0.38
73
650
14
89
1.58
0.81
1.4
1.3
37.43
32.07
%
—
9
56
181
1627
1.13
0.80
2.9
2.8
2.91
2.62
e6/l
0.16
107
898
329
3061
1.10
0.79
5.0
4.7
2.04
2.42
ug/l
1.18
291
2738
6
33
1.82
0.79
1.3
1.6
—
—
—
0
0
6
33
1.82
0.79
1.2
1.2
2.45
1.44
%
—
6
25
6
33
1.82
0.79
1.0
1.5
—
—
—
0
0
0
26
0.00
0.78
0.0
3.2
—
—
—
0
0
301
2790
1.10
0.78
3.7
3.3
—
—
—
0
0
40
314
1.28
0.77
1.9
1.5
0.21
0.24
g/l
1.13
40
300
896
8720
1.10
0.77
23.5
18.3
332.02
332.37
g/l
0.54
891
8653
15
99
1.52
0.75
1.3
1.3
—
—
—
0
0
7
38
1.85
0.73
1.1
1.1
—
—
—
0
0
115
1010
1.15
0.73
4.0
4.2
—
—
—
0
0
6
108
0.55
0.72
1.2
2.6
—
1.37
—
0
59
25
185
1.36
0.72
3.3
2.7
—
—
—
0
0
9
57
1.58
0.71
2.9
2.5
—
—
—
0
0
117
1033
1.15
0.70
1.5
1.5
—
—
—
0
0
7
41
1.71
0.70
34.9
32.5
108.71
122.91
ug/l
—
7
33
10
61
1.64
0.68
1.4
1.5
—
—
—
0
0
10
61
1.64
0.68
1.3
1.5
—
—
—
0
0
16
110
1.46
0.68
1.1
1.3
—
—
—
0
0
7
42
1.67
0.68
1.9
2.2
26.17
216.64
ug/l
—
7
35
24
179
1.35
0.67
1.5
1.3
—
—
—
0
0
14
94
1.49
0.67
1.2
1.1
—
—
—
0
0
23
171
1.35
0.66
1.7
1.5
—
—
—
0
0
7
44
1.59
0.65
1.6
1.8
—
—
—
0
0
19
137
1.39
0.64
1.1
1.0
0.70
2.49
u/ml
—
9
63
17
120
1.42
0.64
1.0
1.0
5.59
4.17
u/ml
—
6
50
180
1644
1.11
0.64
1.8
1.8
—
—
—
0
0
15
104
1.45
0.62
1.5
2.1
—
—
—
0
0
15
104
1.45
0.62
2.1
3.5
—
—
—
0
0
6
105
0.57
0.61
1.2
1.2
—
—
—
0
0
5
30
1.67
0.61
1.2
1.4
—
—
—
0
0
0
21
0.00
0.60
0.0
1.1
—
—
—
0
0
11
162
0.68
0.58
1.0
1.1
—
—
—
0
0
11
162
0.68
0.58
1.0
1.1
—
—
—
0
0
10
64
1.57
0.58
1.2
1.2
21.20
11.25
u/l
—
10
57
1033
10162
1.09
0.58
4.6
4.3
1.49
1.47
mmol/l
0.86
951
9365
8
54
1.48
0.57
1.1
1.1
—
—
—
0
0
8
55
1.46
0.56
1.0
1.0
—
—
—
0
0
13
90
1.45
0.55
3.3
3.1
3.19
18.05
mg/l
—
7
64
19
142
1.34
0.54
5.8
2.2
—
—
—
0
0
96
857
1.13
0.52
3.8
3.8
1.23
1.23
mmol/l
0.06
80
749
6
100
0.60
0.51
1.3
1.2
—
—
—
0
0
6
40
1.50
0.51
16.8
17.1
—
—
—
0
0
997
9812
1.08
0.49
4.1
3.9
1.29
1.31
mmol/l
0.44
916
8995
39
327
1.20
0.47
1.9
1.5
1.15
1.19
g/l
0.41
39
310
12
85
1.42
0.47
1.0
1.4
—
—
—
0
0
7
49
1.43
0.46
1.9
2.6
37271.43
37642.96
ug/l
—
7
49
6
92
0.65
0.42
1.0
1.2
354.67
381.56
nmol/l
—
6
81
12
87
1.38
0.42
1.3
1.4
—
—
—
0
0
5
32
1.56
0.42
1.2
1.1
18.04
33.02
%
—
5
26
83
920
0.90
0.42
1.4
1.4
—
—
—
0
0
8
57
1.41
0.42
1.0
1.6
4.28
7.80
ug/l
—
8
45
22
176
1.25
0.42
1.2
1.2
—
—
—
0
0
5
33
1.52
0.41
1.0
1.1
157.60
310.19
pmol/l
—
5
21
0
15
0.00
0.41
0.0
3.5
—
—
—
0
0
0
15
0.00
0.41
0.0
3.4
—
—
—
0
0
0
16
0.00
0.41
0.0
1.5
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
6.1
—
—
—
0
0
5
34
1.47
0.40
1.6
1.0
—
—
—
0
0
20
159
1.26
0.40
1.2
1.2
—
—
—
0
0
16
204
0.78
0.39
1.8
2.3
—
—
—
0
0
19
151
1.26
0.38
1.2
1.2
—
—
—
0
0
52
458
1.14
0.38
2.2
1.8
—
—
—
0
0
10
136
0.73
0.37
1.7
2.1
—
—
—
0
0
5
37
1.35
0.37
1.2
1.2
64.80
55.15
%
—
5
26
32
375
0.85
0.37
1.0
1.1
—
—
—
0
0
25
207
1.21
0.36
3.5
4.0
57.04
57.59
%
0.06
25
207
28
235
1.20
0.36
3.0
3.8
—
—
—
0
0
12
90
1.34
0.36
1.5
2.0
0.86
2.52
u/field
—
7
40
5
77
0.65
0.35
1.2
2.1
11.84
10.63
%
—
5
77
48
543
0.88
0.35
2.0
1.7
—
—
—
0
0
24
199
1.21
0.35
1.2
1.3
63.63
63.91
mmol/l
0.01
19
164
10
73
1.37
0.34
1.4
1.6
0.91
1.02
g/l
—
10
73
332
3194
1.05
0.34
3.1
3.1
7.18
7.43
mmol/l
0.52
287
2692
313
3007
1.05
0.34
3.2
3.2
879.98
298.24
mg/l
0.77
205
1909
6
45
1.33
0.33
1.0
1.2
27.62
30.81
umol/l
—
6
45
6
45
1.33
0.33
1.2
1.3
—
—
—
0
0
16
198
0.81
0.32
1.2
1.2
—
—
—
0
0
14
110
1.28
0.31
1.3
1.3
—
—
—
0
0
30
258
1.17
0.31
2.2
1.7
15113.17
14580.46
e6/l
0.03
23
190
12
152
0.79
0.29
1.4
1.5
—
—
—
0
0
7
56
1.25
0.29
1.6
2.8
2200.00
1929.12
ml
—
7
51
8
107
0.75
0.29
1.1
1.1
—
—
—
0
0
49
440
1.12
0.29
1.0
1.1
—
—
—
0
0
64
700
0.91
0.28
1.2
1.2
130.90
142.55
iu/ml
0.10
25
278
8
63
1.27
0.27
1.5
1.4
203.88
171.58
pmol/l
—
8
63
22
187
1.18
0.26
1.4
1.4
—
—
—
0
0
9
72
1.25
0.25
4.3
2.1
—
—
—
0
0
9
72
1.25
0.25
1.2
1.0
—
—
—
0
0
23
198
1.16
0.24
1.7
1.6
—
—
—
0
0
12
148
0.81
0.24
1.4
1.4
—
—
—
0
0
53
484
1.10
0.24
5.4
3.9
—
—
—
0
0
10
78
1.28
0.24
1.3
1.6
8.94
12.06
umol/l
—
10
73
49
446
1.10
0.24
1.6
1.9
1.46
1.49
g/l
0.08
40
390
23
199
1.16
0.23
3.1
3.6
3.95
4.26
e9/l
0.34
23
199
12
147
0.81
0.23
1.4
1.4
—
—
—
0
0
20
171
1.17
0.23
1.4
1.4
123.00
106.23
u/ml
—
5
37
12
97
1.24
0.23
1.4
1.4
147548.33
101257.07
e6/l
—
6
54
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
2.0
—
—
—
0
0
5
43
1.16
0.21
1.6
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
10.9
—
6.14
—
0
13
61
654
0.93
0.19
3.4
2.8
—
—
—
0
0
48
518
0.92
0.18
5.5
3.6
—
—
—
0
0
16
185
0.86
0.18
1.2
1.3
188.41
271.29
u/ml
—
7
109
12
100
1.20
0.18
1.3
1.4
—
—
—
0
0
13
110
1.18
0.17
2.3
1.8
—
—
—
0
0
15
129
1.16
0.17
1.3
1.5
58.56
60.82
%
—
9
84
23
257
0.89
0.17
2.1
2.2
233.18
100.21
ug/min
0.30
13
153
8
68
1.18
0.16
1.0
1.1
—
—
—
0
0
44
408
1.08
0.16
2.2
2.6
—
—
—
0
0
76
720
1.06
0.16
2.6
3.3
3.78
6.04
e9/l
1.61
61
590
13
151
0.86
0.15
1.4
1.0
2.28
2.14
u/ml
—
5
64
15
130
1.16
0.15
2.0
1.2
—
—
—
0
0
9
79
1.14
0.15
1.2
1.2
—
—
—
0
0
15
171
0.88
0.14
1.1
1.1
—
—
—
0
0
24
217
1.11
0.14
2.0
2.8
—
—
—
0
0
11
94
1.17
0.13
1.0
1.3
—
—
—
0
0
24
219
1.10
0.12
3.8
3.2
0.77
0.85
nmol/l
0.65
18
173
25
229
1.09
0.12
3.8
3.1
1.31
1.51
mmol/l
1.17
25
224
82
787
1.04
0.12
1.7
1.6
—
—
—
0
0
92
954
0.96
0.11
1.3
1.4
—
—
—
0
0
322
3169
1.02
0.11
3.9
3.8
9.68
9.47
mg/mmol
0.02
209
1983
175
1788
0.98
0.10
3.2
2.9
0.71
0.76
ug/l
0.36
119
1143
29
271
1.07
0.10
2.0
1.8
4.92
4.79
iu/l
0.03
13
94
5
46
1.09
0.09
2.4
2.2
48.80
49.94
umol/l
—
5
36
30
281
1.07
0.09
1.1
1.2
—
—
—
0
0
10
114
0.88
0.09
1.0
1.1
—
—
—
0
0
5
47
1.06
0.09
1.0
1.3
—
5.50
%
—
0
10
28
262
1.07
0.09
3.2
2.3
—
—
—
0
0
6
56
1.07
0.08
1.5
2.1
8.67
9.94
mmol/l
—
6
56
33
349
0.94
0.08
3.4
3.4
0.10
0.28
g/l
3.70
15
146
6
57
1.05
0.08
1.2
1.4
1.18
1.12
nmol/l
—
6
42
17
185
0.92
0.08
1.0
1.2
—
—
—
0
0
8
74
1.08
0.07
1.5
1.4
77.50
81.30
umol/l
—
8
74
8
90
0.89
0.06
1.0
1.2
—
—
—
0
0
16
173
0.92
0.06
1.0
1.0
—
—
—
0
0
14
128
1.09
0.06
7.4
2.1
32.43
32.74
pg
0.11
14
128
9
105
0.86
0.06
2.2
2.5
—
—
—
0
0
11
101
1.09
0.04
1.5
1.6
—
—
—
0
0
59
603
0.98
0.03
1.4
1.4
—
—
—
0
0
26
270
0.96
0.03
6.7
4.8
—
—
—
0
0
14
132
1.06
0.02
1.9
2.6
—
—
—
0
0
10
94
1.06
0.01
1.1
1.1
—
—
—
0
0
110
1093
1.01
0.00
1.9
1.6
—
—
—
0
0
19
184
1.03
0.00
2.7
2.8
—
—
—
0
0
27
276
0.98
0.00
1.0
1.1
—
—
—
0
0
11
109
1.01
0.00
2.2
2.8
—
—
—
0
0
29
287
1.01
0.00
1.2
1.3
—
—
—
0
0
5
56
0.89
0.00
1.2
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.6
—
—
—
0
0
5
54
0.93
-0.00
1.2
3.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
61
0.98
-0.00
1.5
1.3
1.63
1.57
g/l
—
6
61
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
96
0.94
-0.00
2.3
2.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
4.1
—
—
—
0
0
6
64
0.94
-0.00
2.7
3.9
—
—
—
0
0
8
80
1.00
-0.00
1.3
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
54
0.93
-0.00
1.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
8.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
33.51
—
0
7
0
6
0.00
-0.00
0.0
1.5
—
320.67
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
0.06
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
57
0.88
-0.00
1.0
1.2
—
5.71
—
0
15
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_OTHER_NOS and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_OTHER_NOS 1.242 [1.09, 1.41] < 0.001
Birth year 0.991 [0.98, 1.0] 0.039

During the follow-up period (1.1.1998 — 31.12.2019), 549 out of 2966 females with CD2_BENIGN_OTHER_NOS died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_OTHER_NOS 1.366 [1.18, 1.57] < 0.001
Birth year 0.985 [0.98, 1.0] 0.004

During the follow-up period (1.1.1998 — 31.12.2019), 531 out of 2412 males with CD2_BENIGN_OTHER_NOS died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_OTHER_NOS.

N-year risk Females Males
1 0.159% 0.289%
5 0.643% 1.611%
10 1.644% 3.828%
15 3.185% 6.966%
20 5.527% 11.602%

Relationships between endpoints

Index endpoint: CD2_BENIGN_OTHER_NOS – Benign neoplasm of other and unspecified sites

GWS hits: 3

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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