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Benign neoplasm: Other/unspecified site

DOID EFO Endpoint Browser PheWeb

CD2_BENIGN_NOS

benign neoplasm: A neoplasm which is characterized by the absence of morphologic features associated with malignancy (severe cytologic atypia, tumor cell necrosis, and high mitotic rate). Benign neoplasms remain confined to the original site of growth and do not metastasize to other anatomic sites.

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Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — D36.7&, D36.9&
  • Hospital discharge: ICD-9 — 2298B|2899
  • Hospital discharge: ICD-8 — 2289
  • Cause of death: ICD-10 — D36.7&, D36.9&
  • Cause of death: ICD-9 — 2298B|2899
  • Cause of death: ICD-8 — 2289

2 out of 7 registries used, show all original rules.

586

4. Check minimum number of events

None

586

5. Include endpoints

None

586

6. Filter based on genotype QC (FinnGen only)

568

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 4683 2655 1987
Only index persons 3950 2292 1658
Unadjusted period prevalence (%)
Whole population 0.07 0.08 0.06
Only index persons 0.08 0.08 0.06
Median age at first event (years)
Whole population 51.34 50.73 51.95
Only index persons 48.91 48.60 49.34

-FinnGen-

Key figures

All Female Male
Number of individuals 568 335 233
Unadjusted period prevalence (%) 0.11 0.12 0.11
Median age at first event (years) 50.23 47.10 54.72

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
586
Matched controls
5860
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D36.7
ICD-10 Finland
Benign neoplasm: Other specified sites
+∞
307.7
394
*
22899
ICD-8 Finland
Benign neoplasm of other and unspecified organs and tissues
+∞
118.9
110
*
D36.9
ICD-10 Finland
Benign neoplasm: Benign neoplasm of unspecified site
+∞
79.0
74
*
DHB10
NOMESCO Finland
Excision of lesion of internal nose
142.8
38.2
40
*
DHB00
NOMESCO Finland
Excision of lesion of external nose
18.3
21.6
33
19
D14.0
ICD-10 Finland
Benign neoplasm: Middle ear, nasal cavity and accessory sinuses
19.2
20.6
31
17
DHA10
NOMESCO Finland
Biopsy of cavity of nose
17.2
18.0
28
17
D23.3
ICD-10 Finland
Benign neoplasm: Skin of other and unspecified parts of face
5.3
17.4
36
72
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
2.9
14.6
74
278
UDH02
NOMESCO Finland
Rhinopharyngoscopy
3.1
14.1
62
215
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
3.6
13.7
46
134
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.8
10.7
218
1431
J33.0
ICD-10 Finland
Polyp of nasal cavity
4.2
9.5
25
61
2899X
ICD-9 Finland
Other diseases of blood and blood-forming organs, Unspecified diseases of blood and blood-forming organs
+∞
9.4
9
*
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
4.4
9.2
23
54
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
2.6
8.5
49
197
WX302
NOMESCO Finland
Thoracal epidural anesthesy
3.1
8.2
35
119
D37.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Liver, gallbladder and bile ducts
4.9
8.2
18
38
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.8
8.0
131
795
R51
ICD-10 Finland
Headache
2.9
7.7
36
129
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
2.5
7.5
49
209
R01AD08
ATC
fluticasone; nasal
1.7
7.4
166
1100
UDM02
NOMESCO Finland
Sinoscopy
4.0
7.2
20
51
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.3
7.0
55
255
DJW00
NOMESCO Finland
Removal of local lesion of nasal septum
40.5
6.8
8
*
UJF32
NOMESCO Finland
Coloscopy
1.7
6.8
153
1014
A02BC03
ATC
lansoprazole; oral
1.6
6.7
175
1204
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.8
6.7
110
666
J01AA02
ATC
doxycycline; systemic
1.7
6.6
446
3839
J31.0
ICD-10 Finland
Chronic rhinitis
2.2
6.5
55
263
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.3
6.5
50
230
J02AC01
ATC
fluconazole; systemic
1.6
6.4
223
1640
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
3.7
6.4
20
56
R07.4
ICD-10 Finland
Chest pain, unspecified
1.6
6.3
165
1134
DNB30
NOMESCO Finland
Excision of lesion of ethmoidal sinus
+∞
6.3
6
*
P01AB01
ATC
metronidazole; oral, rectal
1.6
6.2
230
1712
A02BC02
ATC
pantoprazole; systemic
1.6
6.2
386
3229
S18
ICPC
Laceration/cut
1.5
6.1
260
1998
AA1BD
NOMESCO Finland
Extensive CT of head and brain
3.5
6.1
20
58

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
300
2206
1.74
9.73
15.5
13.7
1.22
1.25
inr
0.19
82
656
82
433
2.04
7.52
3.0
2.0
351.21
375.54
nmol/l
0.59
76
398
260
1938
1.61
7.31
2.4
2.1
—
—
—
0
0
303
2366
1.58
6.85
6.4
6.4
1.22
1.22
mmol/l
0.02
265
2025
267
2029
1.58
6.76
5.1
4.6
35.56
35.59
g/l
0.03
241
1906
433
3691
1.66
6.69
9.1
7.5
78.07
78.62
u/l
0.08
405
3471
341
2757
1.57
6.48
5.6
4.6
6.55
6.68
mmol/l
0.71
322
2594
94
553
1.83
6.24
2.1
1.6
—
—
—
0
0
417
3572
1.58
5.81
4.7
4.1
11.25
12.18
mm/h
0.75
385
3309
204
1510
1.54
5.53
3.0
2.5
58.88
60.03
u/l
0.09
186
1394
18
52
3.54
5.49
1.6
1.4
—
—
—
0
0
280
2220
1.50
5.47
3.0
2.4
—
—
—
0
0
78
454
1.83
5.35
2.2
2.1
0.22
0.21
g/l
0.50
73
424
309
2528
1.47
5.00
7.2
6.2
11.01
11.31
umol/l
0.18
293
2403
96
609
1.69
4.89
1.4
1.3
—
—
—
0
0
519
4758
1.79
4.89
18.5
14.0
21.72
23.37
mg/l
0.58
429
3785
299
2441
1.46
4.83
6.6
5.6
1.74
1.94
e9/l
2.23
277
2179
147
1041
1.55
4.77
1.7
1.7
1.20
1.11
mg/l
0.17
110
819
269
2156
1.46
4.76
6.7
5.6
1.21
1.22
mmol/l
0.71
247
1971
277
2237
1.45
4.69
8.3
6.1
—
—
—
0
0
331
2775
1.44
4.52
10.1
9.1
4.00
4.07
e9/l
0.20
303
2444
482
4363
1.59
4.41
5.7
4.8
1.83
2.20
mu/l
0.72
444
3987
229
1800
1.45
4.40
4.4
3.7
29.66
54.56
ng/l
0.65
158
1268
84
532
1.68
4.30
6.5
7.2
1.68
1.26
mmol/l
0.44
67
434
289
2379
1.42
4.28
6.7
5.6
0.58
0.58
e9/l
0.09
262
2081
289
2387
1.42
4.16
6.8
5.6
0.04
0.04
e9/l
0.39
263
2090
68
410
1.74
4.15
1.4
1.4
—
—
—
0
0
194
1491
1.45
4.15
2.6
2.2
—
—
—
0
0
39
196
2.06
4.13
2.7
3.2
59.13
1911.06
u/ml
1.22
31
168
297
2469
1.41
4.09
6.9
5.9
0.20
0.19
e9/l
0.26
276
2190
170
1278
1.47
4.07
4.4
4.1
—
—
—
0
0
201
1561
1.44
4.05
3.9
3.5
30.86
32.77
u/l
0.47
186
1487
410
3618
1.44
3.97
5.1
4.0
15.04
14.78
pmol/l
1.17
380
3291
187
1441
1.44
3.91
3.8
3.8
7.41
7.40
ph
0.46
33
271
525
4892
1.70
3.82
20.8
16.1
139.75
139.69
mmol/l
0.24
511
4760
156
1168
1.46
3.78
2.3
2.1
3.10
3.06
mg/l
0.07
125
1000
64
393
1.71
3.68
4.6
3.3
—
—
—
0
0
205
1621
1.41
3.67
3.8
3.4
2.36
2.35
mmol/l
0.61
176
1436
525
4903
1.68
3.65
20.8
16.2
3.96
3.97
mmol/l
0.32
507
4766
29
137
2.17
3.61
1.9
1.7
293.21
294.94
mu/l
0.01
24
126
457
4147
1.46
3.56
19.9
16.8
15.12
14.94
%
0.24
450
4090
96
659
1.55
3.53
1.3
1.2
—
—
—
0
0
150
1130
1.44
3.50
2.4
2.2
—
—
—
0
0
184
1438
1.41
3.50
2.3
2.1
340.26
281.05
u/l
0.18
173
1355
52
307
1.76
3.44
4.1
4.5
—
—
—
0
0
80
530
1.59
3.43
2.9
2.7
11.34
8.58
umol/l
0.31
67
462
47
271
1.80
3.36
4.0
3.4
4.41
4.56
pmol/l
0.53
41
236
371
3266
1.37
3.30
4.9
4.3
—
—
—
0
0
166
1287
1.40
3.27
1.7
1.7
1.43
1.40
mmol/l
0.11
139
1085
57
352
1.69
3.22
3.0
3.6
89.81
83.23
ng/l
0.18
45
320
273
2311
1.34
3.05
7.1
5.8
27.62
27.85
%
0.13
260
2177
269
2276
1.34
3.00
6.5
5.6
57.21
57.12
%
0.04
257
2142
554
5293
1.85
2.98
26.8
20.6
254.32
249.80
e9/l
0.80
544
5161
554
5294
1.85
2.96
27.0
20.6
40.05
40.11
%
0.07
512
4974
128
964
1.42
2.95
3.4
2.9
492.93
553.60
mosm/kgh2o
2.62
111
832
554
5296
1.84
2.93
26.8
20.5
91.24
91.07
fl
0.42
547
5220
554
5297
1.84
2.91
26.9
20.6
6.54
6.69
e9/l
1.12
542
5154
554
5297
1.84
2.91
26.9
20.6
4.46
4.49
e12/l
0.67
542
5157
526
4963
1.58
2.91
17.3
13.0
—
—
—
0
0
17
70
2.47
2.90
1.9
3.4
—
—
—
0
0
554
5299
1.83
2.88
27.1
20.7
134.24
135.14
g/l
0.73
546
5217
167
1323
1.37
2.85
3.1
3.0
0.56
0.50
e6/l
0.05
133
999
235
1965
1.33
2.79
2.3
2.2
80.53
77.02
nmol/l
0.92
207
1760
40
234
1.76
2.76
6.7
9.0
—
—
—
0
0
184
1488
1.34
2.73
3.5
3.0
—
—
—
0
0
136
1049
1.39
2.72
1.2
1.2
0.65
1.42
u/ml
1.24
33
296
553
5297
1.78
2.70
26.8
20.5
30.31
30.30
pg
0.05
546
5219
90
645
1.47
2.70
1.5
1.3
488.89
462.31
titre
0.08
18
156
82
578
1.49
2.67
1.5
1.4
—
—
—
0
0
535
5085
1.60
2.65
12.8
10.3
26.04
26.10
u/l
0.03
521
4906
28
148
1.94
2.65
1.5
1.4
265.65
294.83
ug/g
0.39
20
87
102
753
1.43
2.62
2.1
2.3
12.75
13.09
umol/l
0.17
92
697
29
156
1.90
2.61
1.4
1.7
—
—
—
0
0
158
1259
1.35
2.57
5.1
3.9
0.00
0.01
estimate
0.50
54
427
9
26
3.50
2.49
4.3
7.1
—
—
—
0
0
263
2261
1.30
2.47
7.5
5.9
8.74
8.62
%
0.24
250
2124
6
12
5.04
2.40
2.5
1.8
—
—
—
0
0
15
64
2.38
2.40
2.5
2.9
—
—
—
0
0
268
2317
1.29
2.39
4.9
3.7
0.00
0.00
estimate
0.50
57
473
220
1856
1.30
2.36
4.7
3.4
6.31
5.84
ph
0.95
13
146
135
1065
1.35
2.33
4.8
3.6
—
—
—
0
0
372
3364
1.29
2.29
4.1
3.7
—
—
—
0
0
260
2250
1.28
2.27
7.1
5.6
2.85
2.85
%
0.02
247
2106
253
2183
1.28
2.26
7.1
5.7
0.75
0.68
%
1.35
240
2038
176
1449
1.31
2.25
3.2
3.1
54.65
117.66
e6/l
0.62
142
1123
239
2048
1.28
2.25
3.1
2.7
109.76
120.70
ug/l
0.53
217
1890
42
265
1.63
2.24
1.3
1.3
—
—
—
0
0
74
532
1.45
2.20
1.3
1.3
—
—
—
0
0
267
2325
1.27
2.19
6.5
5.0
0.00
0.00
estimate
-0.00
53
437
269
2346
1.27
2.18
4.8
3.7
0.05
0.01
estimate
0.41
56
426
23
123
1.91
2.14
1.3
1.3
254.67
266.44
miu/ml
0.05
12
58
125
987
1.34
2.14
2.5
2.6
4.47
4.92
e6/l
0.25
114
896
15
68
2.24
2.12
1.1
1.3
—
—
—
0
0
157
1282
1.31
2.12
3.1
2.9
—
—
—
0
0
72
519
1.44
2.12
3.2
4.1
106.84
33.72
ug/l
0.32
63
438
68
488
1.45
2.05
1.8
1.6
—
—
—
0
0
119
939
1.34
2.04
1.4
1.3
2.05
2.49
g/l
2.24
70
564
98
752
1.36
2.02
3.1
3.2
0.80
0.81
mmol/l
0.31
92
706
351
3178
1.26
2.01
3.7
3.1
59.29
49.31
u/l
0.55
321
2974
29
172
1.72
1.97
1.3
1.2
0.15
2.15
u/ml
—
6
13
112
881
1.34
1.96
2.8
3.0
2.48
2.45
mmol/l
1.52
96
779
171
1427
1.28
1.94
4.5
3.8
—
—
—
0
0
21
113
1.89
1.94
1.4
1.2
690.29
486.84
mg/l
0.37
21
106
76
566
1.39
1.88
2.4
2.2
262.21
126.32
ug/g
0.97
62
446
19
100
1.93
1.87
1.4
1.1
11.21
12.66
e6/l
0.06
14
80
80
602
1.38
1.86
5.0
5.4
1.02
1.03
mmol/l
0.06
74
557
79
594
1.38
1.85
1.6
1.6
—
—
—
0
0
108
859
1.32
1.76
1.8
1.7
1039.41
1179.82
nmol/l
0.92
75
652
52
366
1.46
1.76
8.4
7.8
—
—
—
0
0
24
140
1.74
1.74
1.1
1.2
—
378.00
—
0
5
5
13
3.87
1.72
1.2
1.2
—
—
—
0
0
35
228
1.57
1.69
1.1
1.1
—
88.50
titre
—
0
6
90
702
1.33
1.68
2.1
2.0
—
—
—
0
0
489
4651
1.31
1.66
5.2
4.6
5.93
5.96
mmol/l
0.28
443
4258
50
354
1.45
1.65
5.0
4.0
0.00
0.16
%
—
10
98
53
380
1.43
1.64
4.8
4.0
0.14
0.17
%
0.10
14
122
85
660
1.34
1.64
2.1
2.2
23.01
22.34
%
0.13
68
569
56
406
1.42
1.63
4.8
3.9
1.18
1.02
%
0.17
17
148
89
699
1.32
1.59
2.2
2.2
2.35
2.34
g/l
0.05
80
649
55
400
1.41
1.58
7.5
6.5
1.19
1.40
mmol/l
1.26
55
391
239
2113
1.22
1.58
11.2
9.1
0.00
0.00
e9/l
0.54
211
1748
194
1681
1.23
1.55
3.8
3.6
60.66
103.44
e6/l
0.72
151
1201
29
185
1.60
1.54
2.1
2.0
0.56
3.27
ug/l
1.08
29
168
5
15
3.35
1.52
2.2
1.3
74.80
55.00
nmol/24h
—
5
15
144
1214
1.25
1.48
7.4
6.8
—
—
—
0
0
16
87
1.86
1.47
1.4
1.1
—
—
—
0
0
53
389
1.40
1.46
3.9
3.8
—
—
—
0
0
465
4415
1.26
1.46
6.3
5.8
39.18
39.97
mmol/mol
1.26
431
4123
50
364
1.41
1.44
5.0
3.8
0.64
0.61
%
0.04
14
121
104
847
1.28
1.43
1.2
1.3
46.15
34.45
iu/ml
0.28
31
286
124
1033
1.25
1.41
5.3
4.0
1.01
1.02
kg/l
0.54
15
142
164
1413
1.22
1.37
3.1
3.1
999.87
1186.72
ng/l
0.33
135
1196
30
200
1.53
1.35
1.3
1.2
—
—
—
0
0
6
24
2.51
1.30
18.3
9.8
0.62
0.65
mmol/l
—
6
24
8
34
2.37
1.29
2.1
1.8
32.18
38.28
%
—
8
34
13
69
1.90
1.29
1.5
1.1
2.57
3.41
u/ml
—
7
32
51
382
1.37
1.27
3.5
3.5
1.23
1.23
mmol/l
0.03
44
337
16
92
1.76
1.26
5.8
3.1
—
—
—
0
0
8
36
2.24
1.24
1.3
1.1
—
—
—
0
0
26
173
1.53
1.20
5.0
3.9
1.09
1.28
mmol/l
0.74
26
167
8
38
2.12
1.19
1.0
1.2
—
—
—
0
0
11
57
1.95
1.17
5.1
1.9
—
—
—
0
0
217
1946
1.18
1.17
2.1
2.0
97.78
94.89
pmol/l
0.40
104
997
48
362
1.36
1.16
1.1
1.2
—
—
—
0
0
0
35
0.00
1.15
0.0
17.6
—
1652.89
—
0
35
0
35
0.00
1.15
0.0
13.9
—
906.11
—
0
35
16
95
1.70
1.14
3.8
2.5
18.33
15.95
%
—
8
48
12
65
1.86
1.14
2.0
2.7
105.58
105.80
mmol/l
0.06
12
65
12
65
1.86
1.14
2.0
2.7
—
—
—
0
0
12
65
1.86
1.14
2.0
2.7
3.94
4.01
mmol/l
0.23
12
65
31
217
1.45
1.14
4.3
2.4
0.65
0.64
%
0.09
31
217
14
80
1.77
1.13
1.4
1.5
—
—
—
0
0
7
31
2.27
1.10
1.0
1.1
—
8.76
—
0
8
34
464
0.72
1.09
1.3
1.4
—
—
—
0
0
5
21
2.39
1.09
35.6
26.5
92.40
108.25
ug/l
—
5
16
109
925
1.22
1.06
4.2
3.8
201.44
335.00
ng/l
0.51
90
711
12
67
1.81
1.05
1.1
1.1
1.04
2.45
u/ml
—
7
37
42
316
1.35
1.04
1.6
1.4
—
—
—
0
0
5
22
2.28
1.03
2.6
2.9
—
—
—
0
0
50
388
1.32
1.02
4.0
2.7
74.00
70.63
e9/l
0.21
37
299
42
319
1.34
0.99
4.0
3.8
7.42
7.41
ph
—
5
37
65
525
1.27
0.99
2.9
2.7
1.83
1.79
%
0.12
56
474
25
173
1.46
0.99
9.4
4.2
—
—
—
0
0
9
49
1.85
0.99
1.2
1.1
—
—
—
0
0
490
4733
1.22
0.98
4.8
4.4
4.59
4.68
mmol/l
1.10
454
4387
55
437
1.29
0.96
3.1
2.3
43.09
34.35
u/l
0.34
47
371
9
51
1.78
0.95
4.4
1.7
14.06
16.05
ug/l
—
9
51
115
993
1.20
0.94
1.8
1.7
61364132.56
8968496.64
pmol/l
0.40
88
814
143
1260
1.18
0.93
2.7
2.6
328.95
4850.14
umol/l
3.87
128
1108
498
4825
1.21
0.92
5.4
4.9
2.72
2.76
mmol/l
0.56
460
4448
57
458
1.27
0.91
4.4
4.0
—
—
—
0
0
17
110
1.56
0.91
1.1
1.7
—
—
—
0
0
6
29
2.08
0.89
1.2
1.0
—
—
—
0
0
8
43
1.87
0.87
1.3
1.7
—
—
—
0
0
54
435
1.27
0.86
4.3
3.3
2.22
2.10
mmol/l
0.07
47
354
16
104
1.55
0.85
1.3
1.1
4.53
3.81
mmol/l
1.01
16
95
8
46
1.75
0.82
1.0
1.5
—
—
—
0
0
40
313
1.30
0.80
2.2
2.5
3.98
6.27
e9/l
0.97
32
258
30
225
1.35
0.80
4.4
2.4
1.22
1.17
%
0.12
30
225
93
803
1.19
0.78
1.3
1.3
13.81
11.88
u/ml
0.09
45
306
486
4716
1.18
0.78
4.8
4.4
1.46
1.48
mmol/l
0.28
446
4349
89
766
1.19
0.77
3.1
2.7
2.79
2.46
e6/l
0.11
52
417
42
333
1.28
0.77
2.8
2.4
43.53
17.41
au/ml
—
6
19
9
55
1.65
0.73
1.2
1.4
—
—
—
0
0
5
25
2.01
0.73
1.2
1.4
—
—
—
0
0
9
57
1.59
0.71
1.2
1.2
—
—
—
0
0
138
1241
1.15
0.70
1.5
1.4
—
—
—
0
0
18
127
1.43
0.68
1.3
1.3
—
—
—
0
0
18
127
1.43
0.68
2.0
2.9
1.62
1.61
mg/l
0.01
18
115
44
358
1.25
0.67
4.7
2.7
4.54
4.41
kpa
0.15
44
344
5
28
1.79
0.66
1.8
4.7
—
—
—
0
0
10
62
1.62
0.65
1.1
1.0
6.24
5.37
u/ml
—
5
29
5
29
1.73
0.64
1.4
1.3
—
—
—
0
0
30
235
1.29
0.62
4.0
3.8
—
—
—
0
0
469
4561
1.14
0.62
4.2
3.9
1.32
1.30
mmol/l
0.34
423
4184
12
175
0.68
0.61
1.1
1.1
—
—
—
0
0
13
88
1.49
0.61
3.5
3.3
57.38
56.90
%
0.04
13
88
8
51
1.58
0.60
7.0
1.8
31.50
32.45
pg
—
8
51
38
310
1.24
0.58
1.1
1.2
—
—
—
0
0
7
114
0.61
0.58
1.3
1.9
—
—
—
0
0
6
35
1.72
0.58
1.0
1.1
—
2.63
—
0
5
153
1404
1.12
0.57
4.9
4.9
1.78
2.54
ug/l
1.47
129
1258
6
36
1.67
0.57
1.3
1.2
—
—
—
0
0
10
65
1.55
0.56
2.3
1.2
—
—
—
0
0
129
1175
1.13
0.55
1.6
1.5
19.66
21.00
nmol/l
0.50
113
993
12
82
1.47
0.54
1.6
1.3
—
—
—
0
0
25
196
1.29
0.53
2.4
2.6
—
—
—
0
0
13
91
1.44
0.53
3.5
3.2
—
—
—
0
0
6
39
1.54
0.53
1.0
1.1
—
—
—
0
0
6
98
0.61
0.52
1.0
1.5
1.36
0.87
nmol/l
—
6
80
9
135
0.66
0.52
1.2
1.9
—
—
—
0
0
159
1473
1.11
0.51
3.2
3.2
6.71
7.42
mmol/l
1.45
138
1235
31
252
1.24
0.50
2.7
2.5
—
—
—
0
0
29
235
1.25
0.49
6.6
3.5
—
—
—
0
0
7
45
1.56
0.49
1.6
2.0
—
—
—
0
0
26
208
1.26
0.48
2.4
1.7
—
—
—
0
0
82
732
1.14
0.48
1.9
1.8
—
—
—
0
0
10
143
0.69
0.48
1.3
1.8
—
—
—
0
0
10
143
0.69
0.48
1.2
1.8
—
—
—
0
0
12
85
1.42
0.47
3.0
3.0
4.03
4.34
e9/l
0.19
12
85
7
48
1.46
0.47
1.4
1.2
—
—
—
0
0
10
142
0.70
0.46
1.2
1.9
—
—
—
0
0
10
142
0.70
0.46
1.2
1.6
—
—
—
0
0
20
157
1.28
0.44
1.4
1.2
—
—
—
0
0
140
1300
1.10
0.43
4.2
3.4
—
—
—
0
0
40
341
1.19
0.43
1.7
2.3
—
—
—
0
0
6
92
0.65
0.42
2.0
1.3
—
—
—
0
0
5
32
1.57
0.42
1.0
1.3
186.80
167.73
pmol/l
—
5
32
18
228
0.78
0.42
1.1
1.1
—
—
—
0
0
8
59
1.36
0.41
10.4
4.3
—
—
—
0
0
148
1383
1.09
0.40
3.2
3.3
481.55
149.58
mg/l
0.35
92
893
41
353
1.17
0.40
1.3
1.4
—
—
—
0
0
0
18
0.00
0.40
0.0
1.2
—
170.61
—
0
18
7
103
0.68
0.40
2.4
2.3
—
—
—
0
0
16
124
1.30
0.39
9.3
4.6
—
—
—
0
0
9
69
1.31
0.37
1.0
1.0
—
—
—
0
0
5
37
1.35
0.37
1.2
1.5
—
—
—
0
0
20
163
1.24
0.34
1.8
2.0
80.46
557.78
ug/l
1.07
20
151
7
98
0.71
0.31
1.3
1.9
2.82
4.79
mmol/24h
—
7
83
10
75
1.34
0.30
1.2
1.4
—
—
—
0
0
19
157
1.22
0.30
2.2
1.4
0.20
0.23
g/l
0.79
19
151
7
57
1.23
0.29
1.3
1.4
—
—
—
0
0
20
167
1.20
0.29
2.1
1.4
1.11
1.19
g/l
0.53
20
161
19
159
1.20
0.27
8.0
10.8
—
—
—
0
0
153
1458
1.07
0.26
4.1
3.8
14.73
8.83
mg/mmol
0.31
95
913
11
138
0.79
0.26
2.5
3.1
—
—
—
0
0
9
75
1.20
0.25
1.0
1.1
—
—
—
0
0
6
84
0.71
0.24
2.5
1.6
—
—
—
0
0
5
41
1.22
0.22
1.0
1.1
—
—
—
0
0
166
1724
0.95
0.21
3.4
2.9
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
4.5
—
47.50
—
0
11
0
11
0.00
0.21
0.0
1.9
—
50.46
—
0
5
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.6
—
—
—
0
0
27
302
0.89
0.20
3.6
3.0
—
—
—
0
0
6
50
1.20
0.19
2.0
1.8
—
—
—
0
0
6
50
1.20
0.19
2.2
2.5
—
—
—
0
0
6
50
1.20
0.19
1.2
2.5
—
—
—
0
0
11
133
0.82
0.19
1.3
1.4
—
—
—
0
0
7
62
1.13
0.17
1.0
1.2
—
—
—
0
0
5
69
0.72
0.17
1.2
2.4
—
—
—
0
0
22
196
1.13
0.16
1.8
2.1
1.78
1.63
g/l
0.29
17
169
20
225
0.88
0.16
3.7
3.2
24.06
24.29
mmol/l
0.11
20
220
14
120
1.17
0.16
2.6
2.4
—
—
—
0
0
8
70
1.14
0.16
1.0
1.2
—
—
—
0
0
9
80
1.13
0.15
2.2
1.6
—
—
—
0
0
51
481
1.07
0.13
1.3
1.5
—
—
—
0
0
42
396
1.07
0.11
1.4
1.4
—
—
—
0
0
5
44
1.14
0.10
2.4
2.9
—
—
—
0
0
5
46
1.09
0.09
4.8
2.0
12.80
13.17
%
—
5
46
79
817
0.96
0.09
3.1
2.9
0.68
0.76
ug/l
0.37
49
527
5
48
1.04
0.09
1.0
1.1
—
—
—
0
0
9
87
1.04
0.07
4.2
2.8
—
—
—
0
0
8
93
0.86
0.06
1.1
3.1
—
—
—
0
0
31
296
1.05
0.06
1.3
1.4
—
—
—
0
0
18
169
1.07
0.05
4.1
3.4
0.10
0.18
g/l
1.52
11
65
10
91
1.10
0.04
2.0
1.6
—
—
—
0
0
36
348
1.04
0.04
1.8
1.6
—
—
—
0
0
50
512
0.97
0.03
1.6
1.6
—
—
—
0
0
33
320
1.03
0.03
1.3
1.2
92.31
147.65
iu/ml
—
10
132
10
107
0.93
0.02
1.4
3.4
30.50
34.47
umol/l
—
10
95
13
123
1.06
0.01
1.2
1.2
—
—
—
0
0
25
244
1.03
0.00
2.1
1.7
—
—
—
0
0
13
134
0.97
0.00
1.0
1.1
—
—
—
0
0
11
113
0.97
0.00
3.4
4.5
—
—
—
0
0
12
119
1.01
0.00
2.4
1.9
3.60
4.82
iu/l
—
7
42
0
8
0.00
-0.00
0.0
1.4
—
1.72
—
0
8
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
99
0.91
-0.00
1.3
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.2
—
—
—
0
0
6
64
0.94
-0.00
1.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
3.5
—
—
—
0
0
8
84
0.95
-0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
6.03
—
0
8
6
64
0.94
-0.00
1.0
1.1
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint CD2_BENIGN_NOS and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_NOS 1.162 [1.01, 1.34] 0.041
Birth year 0.996 [0.99, 1.0] 0.306

During the follow-up period (1.1.1998 — 31.12.2019), 364 out of 1726 females with CD2_BENIGN_NOS died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_NOS 1.229 [1.03, 1.46] 0.02
Birth year 0.986 [0.98, 1.0] 0.005

During the follow-up period (1.1.1998 — 31.12.2019), 353 out of 1351 males with CD2_BENIGN_NOS died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_NOS.

N-year risk Females Males
1 0.138% 0.241%
5 0.732% 1.341%
10 1.722% 3.462%
15 3.384% 6.531%
20 6.018% 10.979%

Relationships between endpoints

↥

Index endpoint: CD2_BENIGN_NOS – Benign neoplasm: Other/unspecified site

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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