≡ Risteys
FG R12 + FR

Documentation Changelog GitHub Contact & Feedback

Benign neoplasm: Other/unspecified site

DOID EFO Endpoint Browser PheWeb

CD2_BENIGN_NOS

benign neoplasm: A neoplasm which is characterized by the absence of morphologic features associated with malignancy (severe cytologic atypia, tumor cell necrosis, and high mitotic rate). Benign neoplasms remain confined to the original site of growth and do not metastasize to other anatomic sites.

Suggest a new description

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — D36.7&, D36.9&
  • Hospital discharge: ICD-9 — 2298B|2899
  • Hospital discharge: ICD-8 — 2289
  • Cause of death: ICD-10 — D36.7&, D36.9&
  • Cause of death: ICD-9 — 2298B|2899
  • Cause of death: ICD-8 — 2289

2 out of 7 registries used, show all original rules.

564

4. Check minimum number of events

None

564

5. Include endpoints

None

564

6. Filter based on genotype QC (FinnGen only)

564

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 4683 2655 1987
Only index persons 3950 2292 1658
Unadjusted period prevalence (%)
Whole population 0.07 0.08 0.06
Only index persons 0.08 0.08 0.06
Median age at first event (years)
Whole population 51.34 50.73 51.95
Only index persons 48.91 48.60 49.34

-FinnGen-

Key figures

All Female Male
Number of individuals 564 330 234
Unadjusted period prevalence (%) 0.11 0.11 0.10
Median age at first event (years) 49.90 46.84 54.22

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
513
Matched controls
5129
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D36.7
ICD-10 Finland
Benign neoplasm: Other specified sites
+∞
323.0
345
*
22899
ICD-8 Finland
Benign neoplasm of other and unspecified organs and tissues
+∞
110.5
102
*
D36.9
ICD-10 Finland
Benign neoplasm: Benign neoplasm of unspecified site
+∞
60.6
57
*
DHB10
NOMESCO Finland
Excision of lesion of internal nose
93.8
32.2
35
*
DHB00
NOMESCO Finland
Excision of lesion of external nose
19.8
20.2
30
16
D14.0
ICD-10 Finland
Benign neoplasm: Middle ear, nasal cavity and accessory sinuses
21.9
20.2
29
14
DHA10
NOMESCO Finland
Biopsy of cavity of nose
30.3
19.8
26
9
UDH02
NOMESCO Finland
Rhinopharyngoscopy
3.6
11.9
54
161
D23.3
ICD-10 Finland
Benign neoplasm: Skin of other and unspecified parts of face
6.3
11.2
29
48
2899X
ICD-9 Finland
Other diseases of blood and blood-forming organs, Unspecified diseases of blood and blood-forming organs
+∞
9.4
9
*
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
2.7
9.2
62
246
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.8
8.3
179
1176
D37.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Liver, gallbladder and bile ducts
9.1
8.1
16
18
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.9
8.1
47
170
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
3.3
7.7
37
117
DJW00
NOMESCO Finland
Removal of local lesion of nasal septum
+∞
7.3
7
*
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.0
6.7
86
465
WX302
NOMESCO Finland
Thoracal epidural anesthesy
3.2
6.6
33
108
A02BC03
ATC
lansoprazole; oral
1.7
6.5
150
991
A02BC05
ATC
esomeprazole; systemic
1.6
6.4
200
1438
J31.0
ICD-10 Finland
Chronic rhinitis
2.5
6.4
48
203
J02AC01
ATC
fluconazole; systemic
1.6
6.4
196
1402
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
2.6
6.3
42
167
J33.0
ICD-10 Finland
Polyp of nasal cavity
4.2
6.3
22
54
N02BE01
ATC
paracetamol; systemic, rectal
1.8
6.2
426
3756
J01AA02
ATC
doxycycline; systemic
1.7
6.1
386
3311

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
79
419
2.03
7.18
3.0
1.9
354.2
374.5
nmol/l
0.45
73
384
250
1862
1.62
7.08
2.4
2.1
—
—
—
0
0
292
2281
1.58
6.61
6.5
6.4
1.2
1.2
mmol/l
0.01
255
1939
244
1842
1.57
6.32
9.8
8.8
1.2
1.2
inr
0.05
67
535
415
3542
1.65
6.32
9.0
7.5
78.1
78.5
u/l
0.06
390
3328
329
2660
1.57
6.28
5.7
4.5
6.6
6.7
mmol/l
0.67
311
2499
91
534
1.84
6.11
2.1
1.6
—
—
—
0
0
255
1965
1.54
5.92
5.2
4.5
35.5
35.6
g/l
0.09
229
1844
402
3427
1.60
5.91
4.7
4.1
11.1
12.2
mm/h
1.04
372
3173
198
1447
1.57
5.79
3.0
2.4
59.4
56.6
u/l
0.35
182
1331
76
440
1.84
5.32
2.1
2.1
0.2
0.2
g/l
0.44
71
410
300
2431
1.50
5.29
7.2
6.1
10.8
11.3
umol/l
0.33
283
2309
17
49
3.55
5.21
1.6
1.4
—
—
—
0
0
269
2136
1.50
5.21
4.9
3.8
—
—
—
0
0
289
2335
1.49
5.10
6.6
5.7
1.7
1.9
e9/l
2.11
268
2074
92
580
1.70
4.81
1.4
1.3
—
—
—
0
0
320
2660
1.47
4.76
10.0
9.0
4.0
4.1
e9/l
0.20
296
2344
259
2078
1.46
4.57
6.8
5.6
1.2
1.2
mmol/l
0.81
238
1896
279
2280
1.44
4.41
6.7
5.6
0.6
0.6
e9/l
0.02
255
1994
497
4568
1.74
4.41
18.6
14.1
21.9
23.5
mg/l
0.54
412
3637
463
4185
1.59
4.33
5.7
4.8
1.8
2.2
mu/l
0.70
426
3819
279
2292
1.43
4.22
6.8
5.6
0.0
0.0
e9/l
0.42
256
2007
287
2372
1.43
4.19
6.8
5.9
0.2
0.2
e9/l
0.35
269
2104
81
512
1.68
4.19
6.6
7.2
1.6
1.3
mmol/l
0.27
64
413
220
1737
1.44
4.11
4.4
3.6
29.8
35.8
ng/l
0.33
154
1220
140
1012
1.51
4.11
6.1
4.4
—
—
—
0
0
164
1230
1.47
4.00
4.5
4.2
—
—
—
0
0
180
1375
1.45
3.99
2.3
2.1
347.2
241.4
u/l
0.38
169
1295
186
1434
1.44
3.92
2.6
2.2
—
—
—
0
0
394
3472
1.45
3.90
5.1
4.0
15.1
14.8
pmol/l
1.49
364
3158
65
395
1.73
3.88
1.4
1.4
—
—
—
0
0
149
1114
1.46
3.66
2.4
2.1
3.2
3.1
mg/l
0.16
120
955
137
1010
1.47
3.61
1.7
1.7
1.3
1.1
mg/l
0.24
101
795
198
1563
1.41
3.61
3.8
3.4
2.4
2.4
mmol/l
0.50
168
1378
504
4700
1.68
3.59
21.1
16.1
139.8
139.7
mmol/l
0.28
490
4574
37
193
1.98
3.57
2.8
3.0
62.9
1546.1
u/ml
0.97
29
166
79
519
1.61
3.52
2.9
2.7
11.4
8.2
umol/l
0.38
66
452
46
260
1.84
3.51
4.1
3.4
4.4
4.5
pmol/l
0.41
41
228
504
4711
1.66
3.41
21.0
16.3
4.0
4.0
mmol/l
0.24
486
4581
179
1400
1.41
3.40
3.9
3.8
7.4
7.4
ph
0.41
32
262
50
296
1.76
3.29
4.1
4.5
—
—
—
0
0
264
2215
1.36
3.23
7.0
5.8
27.6
27.8
%
0.11
249
2076
56
345
1.69
3.20
3.1
3.5
91.1
82.3
ng/l
0.25
44
313
260
2180
1.36
3.18
6.5
5.6
57.3
57.2
%
0.03
247
2051
143
1092
1.41
3.08
2.4
2.1
—
—
—
0
0
81
553
1.54
3.07
8.8
6.2
104.5
103.9
mmol/l
0.47
81
536
26
127
2.10
3.02
1.9
1.7
283.3
280.8
mu/l
0.02
21
117
354
3129
1.35
2.99
4.9
4.4
—
—
—
0
0
59
377
1.63
2.95
4.7
3.3
—
—
—
0
0
506
4767
1.60
2.91
17.3
13.1
—
—
—
0
0
158
1239
1.38
2.90
1.7
1.7
1.4
1.4
mmol/l
0.09
133
1041
532
5080
1.83
2.87
27.0
20.6
254.4
249.6
e9/l
0.87
524
4951
532
5083
1.82
2.82
26.9
20.6
91.2
91.1
fl
0.18
525
5009
84
589
1.50
2.82
23.5
21.7
1.1
1.3
inr
0.91
13
81
532
5084
1.82
2.80
27.0
20.6
4.5
4.5
e12/l
0.48
522
4947
532
5085
1.81
2.78
27.1
20.6
6.6
6.7
e9/l
0.82
522
4945
39
226
1.78
2.78
6.8
9.0
—
—
—
0
0
532
5086
1.81
2.77
27.2
20.7
134.2
135.1
g/l
0.74
524
5006
80
558
1.51
2.75
1.5
1.4
—
—
—
0
0
89
635
1.48
2.74
1.3
1.2
—
—
—
0
0
99
722
1.45
2.73
2.1
2.3
12.7
13.0
umol/l
0.18
89
664
9
24
3.79
2.68
4.3
7.3
—
—
—
0
0
175
1411
1.35
2.67
3.5
3.0
—
—
—
0
0
87
622
1.47
2.66
1.4
1.3
498.8
463.7
titre
0.10
17
147
419
3833
1.36
2.62
20.7
17.3
13.7
13.7
%
0.07
410
3767
130
1003
1.38
2.61
1.2
1.3
0.7
1.4
u/ml
1.16
32
277
514
4881
1.60
2.60
12.8
10.3
26.0
26.1
u/l
0.08
501
4708
531
5084
1.76
2.60
26.9
20.5
30.3
30.3
pg
0.16
524
5008
254
2169
1.31
2.58
7.4
5.9
8.8
8.6
%
0.30
241
2040
15
62
2.46
2.56
2.5
2.9
—
—
—
0
0
119
908
1.39
2.55
2.9
2.7
491.8
556.0
mosm/kgh2o
2.83
105
781
159
1272
1.35
2.54
3.0
3.0
0.6
0.5
e6/l
0.06
128
956
185
1527
1.31
2.36
7.1
5.7
—
—
—
0
0
29
162
1.83
2.36
1.3
1.2
0.2
2.3
u/ml
—
6
12
251
2159
1.29
2.35
7.1
5.6
2.9
2.8
%
0.10
238
2014
150
1202
1.34
2.35
5.1
4.0
0.0
0.0
estimate
0.50
51
404
41
254
1.66
2.34
1.3
1.3
—
—
—
0
0
71
501
1.48
2.32
3.2
4.0
106.8
29.5
ug/l
0.34
63
425
72
511
1.47
2.29
1.3
1.3
—
—
—
0
0
8
23
3.51
2.27
1.3
1.2
2.0
2.0
mmol/l
—
8
23
244
2100
1.29
2.25
7.1
5.6
0.8
0.7
%
1.73
231
1963
26
144
1.84
2.18
1.4
1.4
268.3
294.5
ug/g
0.32
19
86
27
152
1.82
2.16
1.4
1.6
—
—
—
0
0
96
728
1.38
2.13
3.1
3.3
0.8
0.8
mmol/l
0.21
90
685
22
117
1.92
2.09
1.3
1.3
254.7
273.1
miu/ml
0.08
12
56
357
3240
1.28
2.08
4.1
3.8
—
—
—
0
0
21
110
1.94
2.08
1.4
1.2
690.3
484.6
mg/l
0.38
21
103
5
10
5.03
2.07
1.2
1.1
—
—
—
0
0
227
1957
1.27
2.01
3.1
2.7
105.7
121.9
ug/l
0.92
205
1806
253
2210
1.26
2.01
4.8
3.6
0.0
0.0
estimate
0.00
50
417
13
57
2.31
1.99
1.9
3.1
—
—
—
0
0
19
98
1.97
1.97
1.4
1.1
11.2
12.8
e6/l
0.07
14
79
167
1390
1.29
1.96
3.1
3.2
56.9
121.8
e6/l
0.61
135
1078
78
583
1.39
1.90
5.1
5.5
1.0
1.0
mmol/l
0.09
73
539
164
1369
1.28
1.87
4.6
3.8
—
—
—
0
0
24
137
1.79
1.86
1.1
1.2
—
378.0
—
0
5
118
944
1.32
1.85
2.5
2.6
4.7
5.1
e6/l
0.18
107
838
75
560
1.39
1.84
1.6
1.6
—
—
—
0
0
5
12
4.19
1.82
2.2
1.8
—
—
—
0
0
73
544
1.39
1.81
2.4
2.2
269.9
121.6
ug/g
1.05
60
427
149
1234
1.28
1.80
3.0
2.9
—
—
—
0
0
83
633
1.36
1.79
2.1
2.3
23.4
22.4
%
0.18
66
547
13
60
2.19
1.79
1.1
1.2
—
—
—
0
0
88
678
1.35
1.78
2.2
2.0
—
—
—
0
0
64
468
1.41
1.77
1.9
1.6
—
—
—
0
0
252
2225
1.24
1.75
6.6
5.0
0.0
0.0
estimate
0.00
50
413
107
851
1.32
1.75
2.8
2.8
2.5
2.5
mmol/l
1.46
91
751
254
2245
1.24
1.75
4.8
3.7
0.1
0.0
estimate
0.41
53
405
104
826
1.32
1.72
1.9
1.7
1045.8
1178.9
nmol/l
0.83
74
629
87
674
1.34
1.70
2.2
2.3
2.3
2.3
g/l
0.05
78
627
30
188
1.63
1.69
1.3
1.2
—
—
—
0
0
112
901
1.30
1.69
1.4
1.4
2.1
2.5
g/l
1.86
65
544
141
1170
1.27
1.68
7.5
6.8
—
—
—
0
0
125
1022
1.29
1.67
4.8
3.6
—
—
—
0
0
51
362
1.45
1.66
4.9
4.0
0.2
0.2
%
0.01
11
108
16
83
1.95
1.66
1.4
1.1
—
—
—
0
0
54
388
1.43
1.65
4.9
3.9
1.2
0.9
%
0.22
13
120
48
339
1.45
1.61
5.1
4.1
0.0
0.1
%
—
9
89
50
358
1.44
1.57
8.7
7.6
—
—
—
0
0
7
27
2.61
1.52
1.4
1.7
—
—
—
0
0
23
140
1.67
1.47
5.4
3.8
3.9
3.8
mmol/l
0.15
23
127
48
348
1.41
1.42
5.1
3.9
0.9
0.4
%
—
8
81
448
4253
1.26
1.42
6.3
5.8
39.1
40.0
mmol/mol
1.44
415
3978
211
1862
1.21
1.41
2.1
2.0
97.5
94.8
pmol/l
0.35
102
951
228
2030
1.21
1.38
11.4
9.1
0.0
0.0
e9/l
0.54
203
1678
6
23
2.63
1.37
18.3
9.7
0.6
0.7
mmol/l
—
6
23
48
351
1.40
1.36
1.1
1.2
—
—
—
0
0
100
816
1.27
1.36
1.3
1.3
42.8
34.8
iu/ml
0.17
29
275
32
216
1.51
1.36
1.0
1.1
—
88.5
titre
—
0
6
468
4472
1.27
1.36
5.2
4.6
5.9
6.0
mmol/l
0.15
424
4091
31
448
0.67
1.33
1.3
1.4
—
—
—
0
0
118
987
1.25
1.31
5.3
4.1
1.0
1.0
kg/l
0.56
15
135
14
76
1.86
1.31
1.4
1.5
—
—
—
0
0
16
91
1.78
1.30
5.8
3.1
—
—
—
0
0
115
960
1.25
1.30
1.8
1.7
61364132.6
439.9
pmol/l
0.49
88
787
8
34
2.37
1.29
1.3
1.1
—
—
—
0
0
27
178
1.54
1.28
2.1
2.0
0.6
3.4
ug/l
1.08
27
162
50
373
1.37
1.28
4.1
3.9
—
—
—
0
0
184
1617
1.20
1.26
3.7
3.7
63.5
104.4
e6/l
0.64
144
1156
8
38
2.12
1.19
1.3
1.7
—
—
—
0
0
8
38
2.12
1.19
1.0
1.2
—
—
—
0
0
25
166
1.53
1.17
5.1
4.0
1.1
1.3
mmol/l
0.59
25
161
49
371
1.35
1.16
3.6
3.5
1.2
1.2
mmol/l
0.03
43
327
56
433
1.33
1.15
4.1
4.0
—
—
—
0
0
5
20
2.51
1.15
2.6
3.1
—
—
—
0
0
12
65
1.86
1.14
1.1
1.2
2.5
3.5
u/ml
—
6
31
11
60
1.85
1.03
1.1
1.1
1.2
1.2
u/ml
—
6
23
105
891
1.22
1.03
4.2
3.8
210.0
340.6
ng/l
0.47
86
689
9
47
1.93
1.02
1.2
1.1
—
—
—
0
0
155
1370
1.18
0.98
3.2
3.0
1031.3
1188.4
ng/l
0.25
128
1159
5
23
2.18
0.98
2.6
2.8
—
—
—
0
0
24
166
1.47
0.96
9.7
4.1
—
—
—
0
0
0
32
0.00
0.95
0.0
14.2
—
905.1
—
0
32
0
32
0.00
0.95
0.0
18.0
—
1611.3
—
0
32
16
101
1.60
0.94
1.3
1.1
4.5
3.8
mmol/l
1.08
16
92
29
210
1.40
0.92
4.5
2.3
0.7
0.6
%
0.11
29
202
138
1215
1.18
0.92
2.7
2.6
330.3
4781.3
umol/l
3.64
123
1059
11
64
1.73
0.86
2.1
2.6
—
—
—
0
0
11
64
1.73
0.86
2.1
2.6
3.9
4.0
mmol/l
0.21
11
64
11
64
1.73
0.86
2.1
2.6
105.6
105.8
mmol/l
0.05
11
64
8
45
1.79
0.84
1.5
2.0
—
—
—
0
0
432
4155
1.17
0.84
18.8
15.0
39.8
39.9
%
0.09
291
3009
62
511
1.24
0.82
3.0
2.6
1.8
1.8
%
0.06
54
461
52
420
1.26
0.82
4.4
3.3
2.2
2.1
mmol/l
0.05
45
334
6
32
1.88
0.82
1.0
1.1
—
2.6
—
0
5
470
4555
1.19
0.81
4.8
4.4
4.6
4.7
mmol/l
0.89
437
4218
41
322
1.29
0.80
2.9
2.4
51.2
16.6
au/ml
—
5
12
8
48
1.68
0.79
9.4
3.2
3.9
7.0
nmol/l
—
8
48
47
377
1.27
0.79
4.2
2.7
71.4
70.0
e9/l
0.07
35
288
127
1127
1.16
0.77
1.6
1.5
19.7
21.1
nmol/l
0.52
112
951
478
4645
1.19
0.77
5.4
4.9
2.7
2.8
mmol/l
0.41
442
4276
53
433
1.25
0.77
4.6
3.4
—
—
—
0
0
0
28
0.00
0.76
0.0
1.6
—
12.0
—
0
28
9
53
1.71
0.75
1.2
1.5
—
—
—
0
0
12
75
1.61
0.75
1.6
1.4
—
—
—
0
0
5
24
2.09
0.74
2.4
3.0
22.4
11.8
mu/l
—
5
24
9
55
1.65
0.73
1.2
1.1
—
—
—
0
0
38
300
1.29
0.73
2.2
2.5
4.0
4.0
e9/l
0.04
30
236
5
25
2.01
0.73
1.2
1.4
—
—
—
0
0
13
84
1.56
0.72
3.5
3.4
57.4
56.9
%
0.04
13
84
89
772
1.18
0.72
1.3
1.3
13.8
12.0
u/ml
0.09
45
294
38
301
1.28
0.71
1.7
1.5
—
—
—
0
0
29
222
1.32
0.69
4.0
3.9
—
—
—
0
0
9
59
1.53
0.68
1.1
1.2
—
—
—
0
0
5
27
1.86
0.68
1.2
1.0
—
—
—
0
0
5
28
1.79
0.66
1.8
4.7
—
—
—
0
0
10
62
1.62
0.65
2.4
1.2
—
—
—
0
0
5
29
1.73
0.64
1.4
1.3
—
—
—
0
0
466
4538
1.15
0.63
4.8
4.4
1.5
1.5
mmol/l
0.25
429
4181
8
49
1.64
0.62
7.0
1.8
31.5
32.4
pg
—
8
49
8
49
1.64
0.62
4.3
1.8
14.9
16.2
ug/l
—
8
49
131
1185
1.14
0.62
1.4
1.4
—
—
—
0
0
28
218
1.30
0.61
4.6
2.3
1.3
1.2
%
0.19
28
218
42
345
1.23
0.60
4.9
2.6
4.6
4.4
kpa
0.21
42
332
0
20
0.00
0.60
0.0
1.4
—
—
—
0
0
20
148
1.36
0.60
1.4
1.2
—
—
—
0
0
451
4388
1.14
0.59
4.2
3.9
1.3
1.3
mmol/l
0.48
409
4025
6
35
1.72
0.58
1.3
1.2
—
—
—
0
0
12
81
1.49
0.57
3.0
3.1
4.0
4.3
e9/l
0.19
12
81
146
1338
1.12
0.56
4.9
4.8
1.8
2.6
ug/l
1.35
124
1199
5
89
0.56
0.56
2.0
1.3
—
—
—
0
0
16
217
0.73
0.56
1.1
1.1
—
—
—
0
0
36
294
1.24
0.55
1.1
1.3
—
—
—
0
0
6
37
1.63
0.55
1.0
1.1
—
—
—
0
0
15
108
1.40
0.53
1.1
1.5
—
—
—
0
0
6
99
0.60
0.52
2.7
2.2
—
—
—
0
0
17
126
1.36
0.52
2.1
2.9
1.7
1.6
mg/l
0.08
17
114
25
197
1.28
0.52
2.4
1.8
—
—
—
0
0
135
1239
1.12
0.51
4.3
3.4
—
—
—
0
0
20
154
1.31
0.49
1.8
2.1
80.5
566.9
ug/l
1.03
20
144
7
108
0.64
0.49
1.3
1.9
—
—
—
0
0
7
45
1.56
0.49
1.0
1.5
—
—
—
0
0
16
119
1.35
0.48
9.3
4.6
—
—
—
0
0
30
245
1.24
0.48
2.8
2.5
—
—
—
0
0
7
47
1.50
0.47
1.4
1.2
—
—
—
0
0
28
227
1.25
0.47
6.8
3.5
—
—
—
0
0
12
165
0.72
0.47
1.1
1.1
—
—
—
0
0
13
94
1.39
0.46
4.5
2.5
18.4
15.9
%
—
7
47
9
128
0.70
0.44
1.2
1.9
—
—
—
0
0
5
31
1.62
0.43
1.0
1.3
—
73.5
—
0
8
15
113
1.34
0.43
3.3
3.5
7.8
8.1
kpa
0.22
15
102
6
94
0.63
0.42
1.0
1.5
1.4
0.9
nmol/l
—
6
77
8
59
1.36
0.41
1.4
1.6
—
—
—
0
0
8
59
1.36
0.41
1.4
1.6
—
—
—
0
0
8
59
1.36
0.41
1.4
1.6
—
—
—
0
0
8
59
1.36
0.41
1.4
1.6
—
—
—
0
0
0
17
0.00
0.40
0.0
2.5
—
—
—
0
0
0
17
0.00
0.40
0.0
1.2
—
170.5
—
0
17
12
88
1.37
0.40
3.8
3.3
—
—
—
0
0
151
1416
1.09
0.38
3.3
3.2
6.6
7.4
mmol/l
1.59
130
1178
10
136
0.73
0.38
1.2
1.8
—
—
—
0
0
10
136
0.73
0.38
1.3
1.9
—
—
—
0
0
9
68
1.33
0.37
1.0
1.0
—
—
—
0
0
10
135
0.74
0.36
1.2
1.6
—
—
—
0
0
10
135
0.74
0.36
1.2
1.9
—
—
—
0
0
23
190
1.22
0.35
2.3
2.6
—
—
—
0
0
6
44
1.37
0.34
1.7
2.0
—
—
—
0
0
39
340
1.16
0.34
1.3
1.4
—
—
—
0
0
16
127
1.27
0.34
1.3
1.3
—
—
—
0
0
75
685
1.11
0.33
1.8
1.8
—
—
—
0
0
38
332
1.16
0.33
1.7
2.3
—
—
—
0
0
10
132
0.75
0.32
2.5
3.0
—
—
—
0
0
7
56
1.25
0.29
1.3
1.4
—
—
—
0
0
7
57
1.23
0.29
10.1
3.7
—
—
—
0
0
18
151
1.20
0.25
2.2
1.4
0.2
0.2
g/l
0.67
18
145
9
75
1.20
0.25
1.0
1.1
—
—
—
0
0
19
161
1.19
0.24
2.2
1.4
1.1
1.2
g/l
0.38
19
156
22
190
1.16
0.23
1.8
2.1
1.8
1.6
g/l
0.25
17
164
5
40
1.25
0.22
1.2
1.3
—
—
—
0
0
139
1331
1.06
0.21
3.3
3.3
503.3
155.5
mg/l
0.35
88
855
0
11
0.00
0.21
0.0
4.5
—
47.5
—
0
11
0
11
0.00
0.21
0.0
1.9
—
50.5
—
0
5
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
6
48
1.25
0.20
1.3
2.5
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
6
49
1.23
0.20
2.0
1.7
—
—
—
0
0
7
61
1.15
0.17
1.0
1.2
—
—
—
0
0
26
288
0.90
0.17
3.7
3.0
—
—
—
0
0
5
66
0.76
0.17
1.2
2.4
—
—
—
0
0
46
494
0.93
0.16
1.7
1.6
—
—
—
0
0
161
1661
0.96
0.16
3.5
2.9
—
—
—
0
0
6
80
0.75
0.15
2.5
1.6
—
—
—
0
0
74
777
0.95
0.15
3.1
2.9
0.7
0.8
ug/l
0.18
46
504
11
129
0.85
0.15
1.3
1.3
—
—
—
0
0
40
374
1.07
0.13
1.4
1.4
—
—
—
0
0
144
1401
1.04
0.12
4.4
4.1
15.4
9.1
mg/mmol
0.31
91
877
34
318
1.07
0.11
1.8
1.6
—
—
—
0
0
18
163
1.11
0.11
4.1
3.3
0.1
0.2
g/l
1.50
11
63
5
46
1.09
0.09
2.0
2.4
—
—
—
0
0
5
47
1.06
0.09
1.0
1.1
—
—
—
0
0
7
67
1.05
0.08
1.0
1.1
—
—
—
0
0
10
112
0.89
0.07
3.6
4.3
—
—
—
0
0
9
87
1.04
0.07
2.0
1.6
—
—
—
0
0
9
101
0.89
0.06
2.6
2.1
—
—
—
0
0
30
287
1.05
0.05
1.3
1.4
—
—
—
0
0
13
120
1.09
0.05
1.2
1.2
—
—
—
0
0
12
130
0.92
0.04
1.0
1.1
—
—
—
0
0
47
457
1.03
0.04
1.3
1.5
—
—
—
0
0
16
152
1.05
0.02
8.9
10.8
—
—
—
0
0
12
114
1.05
0.00
2.4
1.9
3.6
4.8
iu/l
—
7
41
23
236
0.97
0.00
1.9
1.8
—
—
—
0
0
0
6
0.00
0.00
0.0
2.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
3.5
—
—
—
0
0
8
85
0.94
0.00
4.6
2.8
—
—
—
0
0
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
8
88
0.91
0.00
1.1
3.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
31
310
1.00
0.00
1.3
1.2
92.3
149.7
iu/ml
—
10
130
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
7
76
0.92
0.00
2.3
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
6
63
0.95
0.00
1.0
1.1
—
—
—
0
0
9
96
0.94
0.00
1.3
1.2
—
—
—
0
0
7
79
0.88
0.00
1.0
1.1
—
—
—
0
0
6
63
0.95
0.00
1.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
6.0
—
0
8
0
6
0.00
0.00
0.0
2.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
1.7
—
0
8
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
3.4
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint CD2_BENIGN_NOS and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_NOS 1.162 [1.01, 1.34] 0.041
Birth year 0.996 [0.99, 1.0] 0.306

During the follow-up period (1.1.1998 — 31.12.2019), 364 out of 1726 females with CD2_BENIGN_NOS died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_NOS 1.229 [1.03, 1.46] 0.02
Birth year 0.986 [0.98, 1.0] 0.005

During the follow-up period (1.1.1998 — 31.12.2019), 353 out of 1351 males with CD2_BENIGN_NOS died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_NOS.

N-year risk Females Males
1 0.138% 0.241%
5 0.732% 1.341%
10 1.722% 3.462%
15 3.384% 6.531%
20 6.018% 10.979%

Relationships between endpoints

↥

Index endpoint: CD2_BENIGN_NOS – Benign neoplasm: Other/unspecified site

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data