Primary adrenocortical insufficiency

E4_PRIMARY_ADRENOCORTICAL_INSUFFICIENCY

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 E27.1
  • Cause of death: ICD-10 E27.1

2 out of 7 registries used, show all original rules.

413

4. Check minimum number of events

None

413

5. Include endpoints

None

413

6. Filter based on genotype QC (FinnGen only)

407

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 407 278 129
Unadjusted period prevalence (%) 0.09 0.10 0.06
Median age at first event (years) 51.93 50.65 54.68

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
413
Matched controls
4130
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H02AB09
ATC
hydrocortisone; systemic
882.6
307.7
367
37
E27.1
ICD-10 Finland
Primary adrenocortical insufficiency
+∞
307.7
413
*
H02AA02
ATC
fludrocortisone; oral
867.1
282.7
247
7
105
Kela drug reimbursment
Adrenal cortical hypofunction
6043.6
275.1
234
*
E27.4
ICD-10 Finland
Other and unspecified adrenocortical insufficiency
266.3
102.6
101
5
E03.80
ICD-10 Finland
Hypothyroidism caused by autoimmune thyroiditis
23.2
102.2
78
41
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
15.3
92.0
88
72
H03AA01
ATC
levothyroxine sodium; systemic
6.1
74.8
223
668
E27.2
ICD-10 Finland
Addisonian crisis
+∞
65.4
61
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
5.4
61.9
183
530
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
137.2
56.5
59
5
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
5.3
50.6
133
342
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
8.4
47.2
67
93
R11
ICD-10 Finland
Nausea and vomiting
5.9
46.7
99
209
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
10.5
45.5
53
57
E23.03
ICD-10 Finland
Lack of ACTH
245.5
43.8
44
*
104
Kela drug reimbursment
Thyroid insufficiency
6.0
42.3
85
170
25510
ICD-8 Finland
Diseases of adrenal glands, Adrenal cortical hypofunction
+∞
37.0
35
*
H04AA01
ATC
glucagon; nasal, parenteral
9.9
36.6
44
49
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.5
34.1
181
747
2554A
ICD-9 Finland
Disorders of adrenal glands, Corticoadrenal insufficiency[MORBUS ADDISON PRIMARIUS]
+∞
31.7
30
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
3.2
29.5
200
939
A10AB05
ATC
insulin aspart; parenteral
4.8
29.4
74
178
E87.5
ICD-10 Finland
Hyperkalaemia
11.5
28.1
30
28
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
8.3
27.6
38
50
E87.6
ICD-10 Finland
Hypokalaemia
7.8
27.6
40
56
R50.9
ICD-10 Finland
Fever, unspecified
3.7
27.2
108
363
E86
ICD-10 Finland
Volume depletion
10.4
27.1
31
32
A41.9
ICD-10 Finland
Sepsis, unspecified
7.7
26.7
39
55
M05BA04
ATC
alendronic acid; oral
4.6
26.6
70
174
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
9.3
25.7
32
37
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
3.8
25.4
91
284
A49.9
ICD-10 Finland
Bacterial infection, unspecified
4.1
24.8
77
217
A10AB04
ATC
insulin lispro; parenteral
6.4
24.5
43
74
R53
ICD-10 Finland
Malaise and fatigue
3.0
24.5
164
749
T89
ICPC
Diabetes insulin dependent
6.0
24.4
46
85
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.9
24.4
225
1217
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
4.9
23.5
56
128
N17.9
ICD-10 Finland
Acute renal failure, unspecified
7.2
23.3
36
54
A10AE05
ATC
insulin detemir; parenteral
4.9
21.7
51
115
E27.0
ICD-10 Finland
Other adrenocortical overactivity
63.5
21.1
24
*
101
Kela drug reimbursment
Anterior pituitary hypofunction
39.5
21.0
26
7
R56.8
ICD-10 Finland
Other and unspecified convulsions
5.7
20.6
40
76
E03.89
ICD-10 Finland
Other specified hypothyroidism
5.8
20.4
39
73
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.3
20.3
89
314
E10
ICD-10 Finland
Type 1 diabetes mellitus
8.0
20.2
28
37
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
8.0
20.2
28
37
E27.9
ICD-10 Finland
Disorder of adrenal gland, unspecified
+∞
20.0
19
*
A10AB01
ATC
insulin (human); parenteral
5.8
19.9
38
71
M05BX04
ATC
denosumab; parenteral
4.8
19.5
47
108
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.7
19.0
69
215
AA4CG
NOMESCO Finland
Extensive MRI examination of sella turcica with high intensity magnet
29.4
18.9
25
9
A10AC01
ATC
insulin (human); parenteral
3.8
18.8
64
191
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
4.1
18.5
55
149
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.3
18.4
80
280
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.1
18.2
91
346
A10AA01, ,
ATC
6.5
17.9
30
49
J46
ICD-10 Finland
Status asthmaticus
6.9
17.7
28
43
C03DA01
ATC
spironolactone; oral
3.4
17.5
70
232
E23.00
ICD-10 Finland
Panhypopituitarism
66.2
16.9
19
*
121
Kela drug reimbursment
Severe hypofunction of sexual glands
6.9
16.4
26
40
C03CA01
ATC
furosemide; systemic
2.5
15.8
142
723
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
18.1
15.8
24
14
M81.9
ICD-10 Finland
Osteoporosis, unspecified
4.8
15.7
37
83
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
20.2
15.7
23
12
J45.8
ICD-10 Finland
Mixed asthma
6.2
15.4
27
46
A08.4
ICD-10 Finland
Viral intestinal infection, unspecified
4.8
15.3
36
81
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.4
15.0
59
193
UJF32
NOMESCO Finland
Coloscopy
2.5
14.9
129
644
J01MA12
ATC
levofloxacin; systemic
2.7
14.8
96
417
215
Kela drug reimbursment
Diabetes, non-insulin-treated
2.5
14.8
117
560
N02AA05
ATC
oxycodone; systemic
2.7
14.6
95
413
JN3AD
NOMESCO Finland
Abdominal CT examination
3.1
14.5
68
247
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.5
14.5
124
614
J01MA02
ATC
ciprofloxacin; systemic
2.3
14.5
184
1082
103
Kela drug reimbursment
Diabetes, insulin-treated
2.4
14.2
125
626
A10AE04
ATC
insulin glargine; parenteral
3.3
14.2
60
205
J45.9
ICD-10 Finland
Asthma, unspecified
2.6
14.1
105
487
TPH04
NOMESCO Finland
Cathetrisation of vein
2.5
13.9
110
524
E05.0
ICD-10 Finland
Thyrotoxicosis with diffuse goitre
5.2
13.8
29
59
A07AA02
ATC
nystatin; oral
3.8
13.8
44
125
M81.0
ICD-10 Finland
Postmenopausal osteoporosis
5.5
13.6
27
52
BCA31
NOMESCO Finland
Endoscopic unilateral adrenalectomy
35.3
13.6
17
5
E89.6
ICD-10 Finland
Postprocedural adrenocortical(-medullary) hypofunction
144.6
13.5
14
*
M79.0
ICD-10 Finland
Rheumatism, unspecified
4.8
13.5
31
68
B03BA03
ATC
hydroxocobalamin; parenteral
4.0
13.4
40
108
E16.2
ICD-10 Finland
Hypoglycaemia, unspecified
15.7
13.2
21
14
XF400
NOMESCO Finland
ECG with 12 standard connections
2.7
13.2
84
360
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
4.3
12.6
34
85
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
5.3
12.6
26
52
E31.00
ICD-10 Finland
APECED syndrome
+∞
12.6
12
*
E31.08
ICD-10 Finland
Autoimmune polyglandular failure
+∞
12.6
12
*
A10AA02, ,
ATC
4.8
12.6
29
64
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
9.4
12.4
25
28
WZC00
NOMESCO Finland
Treatment plan or consultation
2.2
12.3
165
976
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
4.9
12.3
28
61
H02AB06
ATC
prednisolone; systemic
2.1
12.2
220
1454
Z01.8
ICD-10 Finland
Other specified special examinations
2.3
12.1
111
562
M05BA07
ATC
risedronic acid; oral
5.3
12.1
25
50
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.4
12.1
95
449
R03AC12
ATC
salmeterol; inhalant
4.0
12.0
35
93
H02AB07
ATC
prednisone; oral
2.7
12.0
75
318
D64.9
ICD-10 Finland
Anaemia, unspecified
3.1
11.8
53
187
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
4.8
11.8
27
59
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.6
11.6
77
335
K90.0
ICD-10 Finland
Coeliac disease
5.1
11.6
25
52
A04
ICPC
Weakness/tiredness general
2.5
11.4
81
365
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
5.0
11.3
25
53
R03AK06
ATC
salmeterol and fluticasone; inhalant
2.5
11.2
80
361
J01MA14
ATC
moxifloxacin; systemic
3.1
11.2
51
182
E89.00
ICD-10 Finland
Postirradiation hypothyroidism
14.4
11.1
18
13
J01FF01
ATC
clindamycin; systemic
2.2
11.1
128
710
N03AX16
ATC
[U] pregabalin
2.2
11.0
116
620
M80.9
ICD-10 Finland
Unspecified osteoporosis with pathological fracture
11.0
10.9
20
19
N06AA09
ATC
amitriptyline; systemic
2.9
10.9
55
208
A10AE06
ATC
insulin degludec; parenteral
4.1
10.5
29
74
E24.9
ICD-10 Finland
Cushing syndrome, unspecified
112.8
10.5
11
*
E23.09
ICD-10 Finland
Pituitary insufficiency NOS
112.8
10.5
11
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.9
10.4
51
189
B81
ICPC
Anaemia vit B12/folate deficiency
4.6
10.4
25
57
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
4.7
10.4
24
53
AA1AD
NOMESCO Finland
CT of head and brain
2.1
10.3
120
664
R03BB04
ATC
tiotropium bromide; inhalant
2.9
10.3
53
202
SPAT1254
SPAT
Administration of medicine
2.5
10.3
74
334
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
13.6
10.2
17
13
A02BC02
ATC
pantoprazole; systemic
2.0
10.1
286
2162
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.7
10.1
60
247
M80.0
ICD-10 Finland
Postmenopausal osteoporosis with pathological fracture
8.4
10.0
21
26
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
4.0
9.9
29
77
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.8
9.9
52
200
H3600, E103,
ICD-10 Finland
12.6
9.9
17
14
R03DC03
ATC
montelukast; oral
2.3
9.9
90
450
SPAT1262
SPAT
Handing over of treatment supplies
2.3
9.9
82
394
WX892
NOMESCO Finland
Monitored bed care
3.2
9.9
41
138
D44.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Adrenal gland
11.0
9.9
18
17
TPH07
NOMESCO Finland
Cathetrisation of artery
2.8
9.8
54
214
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
2.2
9.7
97
504
107
Kela drug reimbursment
Pernicious anaemia
8.1
9.7
21
27
318
Kela drug reimbursment
Teriparatide
56.3
9.7
11
*
XF600
NOMESCO Finland
Bloodpressure measurement
3.2
9.7
39
129
L28
ICPC
Limited function/disability (L)
2.3
9.6
85
420
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.5
9.5
69
312
N03AE01
ATC
clonazepam; systemic
3.5
9.5
34
104
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
3.1
9.5
40
136
N03AG01
ATC
valproic acid; systemic, rectal
3.3
9.5
37
120
K59.00
ICD-10 Finland
Constipation caused by slow bowel passage (SCT)
5.3
9.4
19
37
E27
ICD-10 Finland
Other disorders of adrenal gland
+∞
9.4
9
*
N05CF01
ATC
zopiclone; oral
2.0
9.2
151
941
N06AX21
ATC
duloxetine; oral
2.5
9.2
66
297
R60.9
ICD-10 Finland
Oedema, unspecified
3.5
9.1
32
97
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
19.1
9.0
13
7
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
5.1
8.9
19
39
R03AK08
ATC
formoterol and beclometasone; inhalant
3.6
8.8
29
84
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.6
8.8
55
232
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
4.4
8.8
22
52
D35.2
ICD-10 Finland
Benign neoplasm: Pituitary gland
14.4
8.7
14
10
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
4.1
8.7
24
61
H05AA02
ATC
teriparatide; parenteral
51.1
8.7
10
*
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.9
8.6
141
876
R06.0
ICD-10 Finland
Dyspnoea
2.0
8.5
125
746
106
Kela drug reimbursment
Hypoparathyroidism
28.2
8.5
11
*
E28.3
ICD-10 Finland
Primary ovarian failure
20.5
8.5
12
6
E27.8
ICD-10 Finland
Other specified disorders of adrenal gland
91.9
8.4
9
*
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
3.7
8.4
27
77
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
4.2
8.4
22
54
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.8
8.3
44
170
R4190
NOMESCO Finland
Nutritional therapy
3.8
8.3
25
68
ZX120
NOMESCO Finland
Intravenous
2.6
8.3
51
213
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.6
8.2
52
220
E03.0
ICD-10 Finland
Congenital hypothyroidism with diffuse goitre
12.0
8.1
14
12
Z3231
NOMESCO Finland
Registered nurse
1.9
8.1
127
774
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.2
8.1
75
377
WZC30
NOMESCO Finland
Teaching
2.2
8.1
74
370
R03DA04
ATC
theophylline; systemic, rectal
3.3
8.0
31
100
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
4.6
8.0
19
43
H02AB04
ATC
methylprednisolone; systemic
2.3
8.0
67
323
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
3.4
8.0
29
90
J02AC01
ATC
fluconazole; systemic
1.8
7.9
184
1267
H03BB01
ATC
carbimazole; oral
3.5
7.9
28
85
X59
ICD-10 Finland
Exposure to unspecified factor
2.1
7.9
88
475
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
11.1
7.8
14
13
A12AA04
ATC
calcium carbonate; oral
9.7
7.8
15
16
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.8
7.8
39
146
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
3.0
7.8
36
129
K59.09
ICD-10 Finland
Constipation, unspecified
3.0
7.8
36
129
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
3.5
7.8
27
81
A06AD11
ATC
lactulose; oral
2.2
7.8
68
333
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.3
7.7
30
97
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.7
7.7
44
177
N03AX12
ATC
[U] gabapentin; oral
2.1
7.7
83
443
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.8
7.6
184
1278
I95.1
ICD-10 Finland
Orthostatic hypotension
4.0
7.6
22
58
UGC12
NOMESCO Finland
Flexible bronchoscopy
2.8
7.6
38
143
UJF30
NOMESCO Finland
Ileoscopy through colon
2.5
7.5
51
223
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
3.3
7.5
28
88
R02
ICPC
Shortness of breath/dyspnoea
2.3
7.5
63
303
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
3.5
7.5
26
78
R42
ICD-10 Finland
Dizziness and giddiness
2.0
7.5
100
575
N06AB04
ATC
citalopram; systemic
2.0
7.5
98
560
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.1
7.5
76
396
BCA30
NOMESCO Finland
Unilateral adrenalectomy
81.5
7.4
8
*
D51.0
ICD-10 Finland
Vitamin B12deficiency anaemia due to intrinsic factor deficiency
13.7
7.4
12
9
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
3.5
7.4
25
74
B37.09
ICD-10 Finland
Unspecified candidal stomatitis
11.1
7.3
13
12
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
3.2
7.3
29
95
E25.01
ICD-10 Finland
Congenital adrenal hyperplasia
+∞
7.3
7
*
WX408
NOMESCO Finland
General anesthesy, balanced
1.9
7.3
112
675
A03FA01
ATC
metoclopramide; systemic, rectal
1.9
7.3
103
604
UJD02
NOMESCO Finland
Gastroscopy
3.3
7.3
28
90
N91.1
ICD-10 Finland
Secondary amenorrhoea
6.8
7.2
17
26
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.5
7.2
46
196
A02BA02
ATC
ranitidine; systemic
2.0
7.2
88
491
E34.9
ICD-10 Finland
Endocrine disorder, unspecified
20.4
7.2
10
5
H3603, E103,
ICD-10 Finland
20.4
7.2
10
5
A06AC01
ATC
ispaghula (psylla seeds); oral
1.9
7.2
116
711
A46
ICD-10 Finland
Erysipelas
2.2
7.1
61
296
B37.08
ICD-10 Finland
Other candidal stomatitis
12.3
7.1
12
10
SPAT1229
SPAT
Assessment of need for aid
2.7
7.1
38
148
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
3.1
7.1
29
97
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
3.1
7.1
29
97
G40.9
ICD-10 Finland
Epilepsy, unspecified
4.0
7.1
20
52
M48.0
ICD-10 Finland
Spinal stenosis
2.3
7.1
56
263
N05BA01
ATC
diazepam; systemic, rectal
2.2
7.1
63
311
CL2S4
NOMESCO Finland
Ocular fundus photography for diabetic retinopathy screening
4.5
7.0
17
39
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.8
7.0
165
1131
SPAT1255
SPAT
Intravenous administration of medicine
3.1
7.0
30
103
A11CC03
ATC
alfacalcidol; systemic
5.6
7.0
19
35
M80.4
ICD-10 Finland
Drug-induced osteoporosis with pathological fracture
14.1
6.9
11
8
R51.80
ICD-10 Finland
Headache
2.0
6.9
87
489
A03CA02
ATC
clidinium and psycholeptics; oral
3.2
6.9
28
93
N05CD07
ATC
temazepam; oral
2.3
6.9
52
239
R41.0
ICD-10 Finland
Disorientation, unspecified
4.2
6.9
18
44
N03AX14
ATC
levetiracetam; systemic
4.4
6.8
17
40
E24.0
ICD-10 Finland
Pituitary-dependent Cushing disease
40.7
6.8
8
*
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.7
6.7
37
146
K29.4
ICD-10 Finland
Chronic atrophic gastritis
6.6
6.7
16
25
SPAT1260
SPAT
Consultation of another employee
2.0
6.7
79
434
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.7
6.6
176
1245
ZXD05
NOMESCO Finland
Urgent procedure
1.8
6.6
133
869
H3601, E103,
ICD-10 Finland
10.3
6.6
12
12
J45
ICD-10 Finland
Asthma
2.3
6.6
52
244
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.4
6.6
47
211
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.7
6.5
223
1685
N02AX02
ATC
tramadol; systemic, rectal
1.7
6.5
175
1239
Y57
ICD-10 Finland
Adverse effects in the therapeutic use of other and unspecified drugs and medicaments
5.9
6.5
17
30
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.4
6.5
23
70
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
2.5
6.5
40
167
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.5
6.5
40
167
K59.1
ICD-10 Finland
Functional diarrhoea
2.8
6.5
32
119
L29
ICPC
Musculoskeletal sympt/complt other
2.5
6.5
42
180
R52.2
ICD-10 Finland
Other chronic pain
3.2
6.5
26
86
M01AH01
ATC
celecoxib; oral
2.0
6.4
78
433
SAA04
NOMESCO Finland
Special examination of mouth
3.0
6.4
29
103
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.8
6.4
125
808
WX882
NOMESCO Finland
High dependency care
5.3
6.4
18
35
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.6
6.4
21
61
R55
ICD-10 Finland
Syncope and collapse
2.2
6.4
53
254
E13.9
ICD-10 Finland
Other specified diabetes mellitus, without complications
9.5
6.3
12
13
E05.9
ICD-10 Finland
Thyrotoxicosis, unspecified
3.8
6.3
19
52
E31.0
ICD-10 Finland
Autoimmune polyglandular failure
+∞
6.3
6
*
E31.01
ICD-10 Finland
Schmidt's syndrome
+∞
6.3
6
*
R89.1
ICD-10 Finland
Abnormal findings in specimens from other organs, systems and tissues, abnormal level of hormones
+∞
6.3
6
*
2581B
ICD-9 Finland
Polyglandular dysfunction and related disorders, Other combinations of endocrine dysfunction[AUTOIMMUNE-POLYENDOCRINOPATHY-CANDIDOSIS-ECTOD DYST]
+∞
6.3
6
*
V04CD01
ATC
metyrapone; oral
+∞
6.3
6
*
N06AX16
ATC
venlafaxine; oral
2.0
6.2
69
370
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
3.4
6.2
22
67
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.9
6.2
84
484
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
4.2
6.1
16
39
BC1AD
NOMESCO Finland
CT of adrenal glands
8.8
6.1
12
14
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.8
6.1
30
112
Z3229
NOMESCO Finland
Other healthcare associate professional
2.4
6.0
42
186
N30.9
ICD-10 Finland
Cystitis, unspecified
2.6
6.0
34
136

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
143
36
60.23
245.10
2.7
1.3
—
—
—
0
0
252
320
18.64
210.75
5.2
2.1
290.95
374.01
nmol/l
2.34
228
295
68
5
162.23
66.13
1.3
1.0
—
—
—
0
0
329
1557
6.47
60.06
14.1
6.6
1.20
1.22
mmol/l
2.61
271
1338
110
225
6.30
54.20
3.7
3.5
4.34
4.56
pmol/l
1.29
97
199
303
1419
5.26
53.64
13.1
6.0
1.20
1.22
mmol/l
2.70
295
1303
211
777
4.51
50.77
5.8
4.1
—
—
—
0
0
139
384
4.95
48.24
6.1
5.2
1.07
1.03
mmol/l
0.77
133
351
235
987
4.20
46.05
8.8
3.7
7.40
7.40
ph
0.11
78
173
155
483
4.54
45.87
4.6
3.7
0.79
0.82
mmol/l
2.44
143
455
285
1394
4.37
44.41
4.2
2.4
77.35
75.95
nmol/l
0.37
269
1262
51
55
10.44
43.63
1.4
1.1
43.04
20.15
iu/ml
0.46
21
13
36
32
12.23
34.91
1.5
1.1
269.93
278.27
mosm/kgh2o
0.90
30
26
99
274
4.44
33.20
1.4
1.2
322.37
161.80
iu/ml
1.61
37
112
318
1882
4.00
33.16
9.2
4.7
7.12
6.57
mmol/l
2.26
307
1736
190
837
3.35
31.73
1.9
1.3
1.62
1.91
u/ml
0.12
52
234
114
363
3.96
31.45
9.9
6.8
102.18
103.95
mmol/l
2.20
114
363
162
658
3.41
30.73
3.5
2.7
478.75
531.25
mosm/kgh2o
2.22
144
570
175
751
3.31
30.24
2.1
1.4
2.03
2.25
g/l
1.10
108
469
94
274
4.15
29.17
5.6
4.0
1.87
2.02
mmol/l
0.14
77
223
235
1223
3.14
28.74
2.7
1.9
97.99
95.07
pmol/l
0.42
147
613
121
431
3.56
27.94
2.8
2.3
2.24
2.39
g/l
2.35
112
397
100
320
3.80
27.06
9.7
8.4
0.85
1.28
mmol/l
0.43
79
258
83
233
4.21
26.98
3.5
3.5
57.70
76.85
ng/l
2.35
66
209
71
177
4.64
26.91
7.0
6.8
25.25
24.96
mmol/l
0.21
71
177
246
1348
3.04
26.83
7.2
4.2
34.74
36.07
g/l
3.46
234
1260
39
56
7.59
26.33
4.5
2.5
—
—
—
0
0
65
154
4.82
26.20
2.1
1.5
351.07
319.24
mu/l
0.38
56
136
84
244
4.07
26.01
8.9
7.6
—
—
—
0
0
98
318
3.73
25.90
9.8
8.4
12.58
12.46
kpa
0.08
93
308
83
241
4.06
25.70
5.5
3.8
4.06
4.60
kpa
2.16
77
236
112
408
3.39
24.66
3.0
2.3
24.78
22.87
%
0.59
101
354
169
795
2.91
23.73
3.2
2.2
2.79
3.11
mg/l
1.25
156
677
121
472
3.21
23.71
3.0
2.3
12.90
13.53
umol/l
0.42
110
440
36
56
6.95
22.57
3.6
2.5
15.36
16.59
%
1.04
22
29
58
141
4.62
22.54
1.4
1.0
—
—
—
0
0
186
950
2.74
21.95
3.0
2.1
180.11
268.25
u/l
0.58
179
905
81
261
3.62
21.37
10.3
9.2
123.16
121.93
g/l
0.21
81
255
79
252
3.64
21.15
3.3
3.1
9.81
10.22
g/l
0.38
71
239
363
2658
4.02
21.13
10.2
4.1
15.58
14.70
pmol/l
8.15
349
2439
274
1725
2.75
20.85
8.6
5.6
9.80
10.61
umol/l
1.35
267
1631
35
58
6.50
20.65
4.5
2.5
4.04
2.94
mmol/l
0.67
26
35
35
58
6.50
20.65
4.5
2.5
5.13
4.99
kpa
0.44
35
58
35
58
6.50
20.65
4.5
2.5
8.44
8.87
kpa
0.66
35
58
65
187
3.94
20.17
5.2
3.8
7.41
7.41
ph
0.01
18
21
80
273
3.39
19.20
2.5
2.5
0.22
0.23
g/l
0.55
71
255
48
115
4.59
18.92
1.6
1.2
16.93
10.96
u/l
1.13
42
95
252
1575
2.54
18.60
9.6
6.4
—
—
—
0
0
346
2551
3.20
17.94
13.3
7.0
75.16
77.22
u/l
0.36
341
2383
232
1421
2.44
17.53
13.8
11.7
1.14
1.21
inr
1.01
99
429
259
1673
2.47
17.29
8.1
6.1
0.04
0.04
e9/l
0.31
233
1475
30
51
6.26
17.22
4.0
2.6
—
—
—
0
0
241
1512
2.43
17.11
17.5
9.1
0.00
0.00
e9/l
0.60
208
1258
264
1725
2.47
17.10
8.3
6.4
0.16
0.18
e9/l
1.34
238
1545
258
1669
2.45
17.08
8.1
6.0
0.62
0.56
e9/l
3.23
232
1473
167
894
2.46
16.89
3.9
2.9
0.29
0.35
e6/l
0.38
142
674
183
1024
2.41
16.73
3.8
2.4
50.27
56.36
u/l
1.27
176
950
262
1717
2.44
16.69
8.1
6.1
1.91
1.92
e9/l
0.07
240
1550
245
1560
2.40
16.65
8.2
6.0
2.28
2.81
%
3.53
240
1464
190
1083
2.40
16.64
4.8
3.0
2.32
2.36
mmol/l
2.12
175
960
239
1506
2.39
16.63
8.4
6.1
0.58
0.69
%
2.37
233
1403
31
57
5.80
16.44
1.7
1.4
0.33
0.37
nmol/l
0.14
24
45
250
1612
2.40
16.42
8.3
6.1
26.29
28.60
%
2.28
245
1523
245
1568
2.38
16.34
8.5
6.3
8.06
8.36
%
0.88
240
1476
42
103
4.43
16.03
2.8
1.7
3.42
3.71
ug/l
0.04
37
94
38
86
4.77
16.01
2.3
2.3
7.60
12.28
mg/l
2.65
33
79
106
473
2.67
15.55
1.5
1.4
646.67
508.62
titre
0.26
12
109
137
692
2.47
15.51
3.0
2.5
6.98
6.72
e6/l
0.06
128
624
56
176
3.52
15.14
11.6
9.6
23.28
24.55
mmol/l
1.22
56
168
63
215
3.28
14.96
2.0
1.7
1.23
1.35
g/l
0.24
57
201
74
280
3.00
14.75
4.7
4.5
1.36
0.85
%
1.03
36
105
243
1596
2.27
14.62
7.8
5.9
58.95
57.01
%
1.38
238
1505
70
261
3.03
14.30
4.6
4.7
0.09
0.18
%
0.53
32
85
279
1952
2.32
14.25
11.8
9.3
4.90
4.03
e9/l
5.62
255
1715
74
287
2.92
14.08
1.6
1.2
—
—
—
0
0
197
1212
2.20
13.64
5.8
3.6
24.92
31.79
ng/l
0.67
153
776
29
60
5.12
13.53
3.1
3.9
61.55
58.17
%
0.63
29
60
58
202
3.18
13.27
3.5
2.3
11.49
13.00
nmol/l
0.64
51
191
157
890
2.23
13.24
3.9
2.8
—
—
—
0
0
86
373
2.65
13.18
2.7
1.5
—
—
—
0
0
169
989
2.20
13.15
4.3
3.0
18.40
103.80
e6/l
0.72
142
763
30
66
4.82
13.04
2.8
1.7
4.55
4.37
mmol/24h
0.11
25
56
54
184
3.23
12.80
8.0
6.5
—
—
—
0
0
48
152
3.44
12.79
5.0
3.6
1.18
1.22
%
0.06
48
152
36
94
4.10
12.64
1.9
1.7
212.40
4.85
iu/l
0.48
15
28
47
148
3.46
12.63
4.7
3.6
0.71
0.65
%
0.67
47
148
44
138
3.45
11.88
10.5
11.9
—
—
—
0
0
63
247
2.83
11.67
4.4
4.5
0.67
0.57
%
0.20
27
83
61
237
2.85
11.48
2.0
3.0
64.82
67.22
g/l
1.69
55
220
323
2506
2.33
11.45
6.3
4.1
13.43
10.96
mm/h
2.48
304
2318
27
61
4.67
11.37
1.8
4.8
—
—
—
0
0
63
252
2.77
11.22
4.7
4.7
0.00
0.13
%
0.66
25
75
185
1176
2.04
11.12
5.0
3.6
29.47
96.24
e6/l
2.34
151
826
26
59
4.64
10.89
2.9
3.4
4.74
4.59
e9/l
0.10
26
59
68
288
2.63
10.82
4.4
3.7
—
—
—
0
0
16
9
18.43
10.80
1.2
2.2
0.91
1.44
ug/l
—
16
9
226
1556
2.00
10.72
4.3
2.7
124.60
95.00
ug/l
1.56
215
1453
92
452
2.33
10.63
1.4
1.2
—
—
—
0
0
21
41
5.34
10.42
2.6
1.3
—
—
nmol/l
—
0
0
54
207
2.85
10.39
1.4
1.2
—
—
—
0
0
21
42
5.21
10.15
1.7
4.1
206.83
72.67
u/ml
—
6
15
52
198
2.86
10.13
1.6
2.7
—
—
—
0
0
16
11
15.07
10.07
2.5
1.3
934.37
53.00
nmol/24h
0.70
16
11
105
557
2.19
10.04
2.0
1.7
1302.35
1227.34
nmol/l
0.32
87
424
25
59
4.45
9.98
1.6
1.9
0.64
0.69
g/l
0.06
16
50
132
770
2.05
9.82
2.3
1.8
0.76
1.02
mg/l
1.47
97
596
140
840
2.01
9.60
4.4
3.3
1051.66
972.23
ng/l
0.15
125
715
372
3155
2.80
9.53
11.5
4.9
2.41
2.23
mu/l
0.10
356
2914
40
136
3.15
9.48
5.2
3.8
—
—
—
0
0
19
37
5.33
9.45
1.8
1.2
0.41
0.39
g/l
0.10
11
28
19
37
5.33
9.45
1.8
1.2
6.51
6.47
g/l
0.02
11
29
19
37
5.33
9.45
1.8
1.2
2.70
2.58
g/l
0.09
11
28
34
105
3.44
9.39
8.2
9.0
1.01
0.88
%
0.95
34
98
126
735
2.03
9.30
1.9
1.5
19.36
21.07
nmol/l
0.77
120
629
73
343
2.37
9.26
2.3
3.2
1.92
1.77
%
0.46
58
313
77
374
2.30
9.05
3.2
2.5
4.77
8.30
umol/l
2.32
59
331
56
235
2.60
9.03
2.7
3.0
77.66
71.76
e9/l
0.44
41
182
20
43
4.84
8.92
2.7
1.3
—
—
—
0
0
36
120
3.19
8.82
10.6
4.9
—
—
—
0
0
29
84
3.64
8.81
1.2
4.7
24.52
55.50
mg/l
1.28
20
69
85
439
2.18
8.59
2.8
2.0
—
—
—
0
0
37
129
3.05
8.41
1.9
2.4
1.40
1.41
g/l
0.01
31
113
49
200
2.65
8.35
1.7
1.3
27.88
24.91
iu/l
0.23
43
172
33
108
3.23
8.33
8.7
8.8
1.62
1.56
%
0.13
33
100
169
1125
1.85
8.22
4.9
3.0
32.03
30.70
u/l
0.23
164
1074
18
38
4.91
8.19
2.2
1.2
—
—
—
0
0
28
84
3.50
8.08
1.3
4.7
20.25
26.36
mg/l
1.08
19
67
103
587
2.01
7.97
5.1
2.7
2.45
2.45
mmol/l
0.07
92
512
159
1047
1.84
7.95
4.8
2.9
—
—
—
0
0
112
662
1.95
7.79
2.2
1.7
453.60
444.39
pmol/l
0.14
95
562
291
2315
1.87
7.65
7.4
4.2
—
—
—
0
0
355
3029
2.22
7.54
9.3
5.3
42.68
39.34
mmol/mol
4.89
345
2851
23
64
3.75
7.41
1.2
5.2
—
—
—
0
0
37
140
2.80
7.28
1.4
1.3
0.28
2.77
u/ml
—
6
10
83
451
2.05
7.28
1.9
2.5
160.03
117.19
ug/g
0.47
70
354
134
856
1.84
7.27
1.7
1.6
1.42
1.38
mmol/l
0.14
115
731
17
38
4.62
7.24
1.8
1.8
—
—
—
0
0
89
499
2.00
7.15
3.8
2.8
5.62
3.07
e6/l
0.68
54
266
37
145
2.70
6.82
1.3
1.6
—
9.23
—
0
6
143
947
1.78
6.81
4.3
3.0
6.35
7.65
mmol/l
3.51
128
814
134
877
1.78
6.61
5.0
3.6
—
—
—
0
0
12
12
10.26
6.57
4.4
2.3
301.17
84.58
nmol/l
0.47
12
12
63
320
2.14
6.57
3.0
2.1
28.17
34.36
u/l
0.77
54
270
18
34
5.49
6.54
4.4
2.2
8.57
3.72
nmol/l
1.10
18
34
131
859
1.77
6.38
8.7
7.1
—
—
—
0
0
128
837
1.77
6.28
4.4
3.2
88.67
131.37
mg/l
0.22
81
539
72
392
2.01
6.23
1.9
1.4
—
—
—
0
0
21
63
3.46
6.08
2.2
1.8
155.90
237.19
pmol/l
1.80
21
58
21
65
3.35
5.81
3.5
2.5
—
—
—
0
0
221
1702
1.64
5.74
5.6
3.7
0.00
0.01
estimate
0.50
67
327
17
36
4.88
5.67
1.8
1.6
32.18
32.83
pg
0.28
17
36
218
1679
1.63
5.61
5.6
3.6
0.00
0.00
estimate
-0.00
73
357
217
1681
1.61
5.37
7.6
4.8
0.00
0.00
estimate
-0.00
70
336
130
889
1.67
5.29
5.1
3.8
20.18
9.09
mg/mmol
0.89
83
560
16
44
3.74
5.25
2.3
4.7
53.69
61.55
%
0.68
16
44
182
1358
1.61
5.22
4.5
3.3
5.91
5.84
ph
0.13
17
111
138
964
1.65
5.15
5.1
3.2
—
—
—
0
0
203
1558
1.60
5.15
3.0
2.4
—
—
—
0
0
25
93
2.80
5.10
1.6
1.3
274.69
320.97
ug/g
0.51
16
52
132
918
1.64
4.99
5.6
4.0
0.00
0.00
estimate
-0.00
70
336
145
1035
1.62
4.93
3.1
2.2
—
—
—
0
0
274
2272
1.61
4.91
5.1
3.6
—
—
—
0
0
15
37
4.17
4.45
3.1
3.1
—
—
—
0
0
51
277
1.96
4.43
8.1
4.2
—
—
—
0
0
22
83
2.74
4.39
1.2
1.2
—
—
—
0
0
20
72
2.87
4.35
1.3
1.5
1.11
0.89
nmol/l
0.34
13
60
23
91
2.62
4.21
4.1
3.0
—
—
—
0
0
19
68
2.88
4.18
1.1
1.9
—
—
—
0
0
33
159
2.17
3.94
2.3
2.2
3.20
3031.67
u/l
1.47
15
70
14
43
3.33
3.94
1.4
1.2
—
—
—
0
0
7
237
0.28
3.87
1.6
1.4
—
—
—
0
0
16
55
2.99
3.78
8.1
13.5
14.00
11.02
mmol/l
2.28
16
49
16
55
2.99
3.78
8.1
13.5
99.44
105.35
mmol/l
1.83
16
49
6
5
12.15
3.77
3.5
1.2
—
—
—
0
0
14
45
3.19
3.68
2.9
3.1
—
—
—
0
0
9
16
5.72
3.67
1.0
1.1
—
—
—
0
0
8
13
6.25
3.51
1.6
1.1
186.75
176.90
mmol/24h
—
8
13
8
13
6.25
3.51
1.0
1.1
—
—
—
0
0
369
3400
1.80
3.41
33.8
12.9
21.94
21.29
mg/l
0.17
336
2634
17
389
0.41
3.35
1.2
1.3
—
—
—
0
0
112
816
1.51
3.29
3.2
2.6
2478.37
5858.71
umol/l
0.69
89
721
6
7
8.67
3.27
2.3
2.3
—
—
—
0
0
61
386
1.68
3.24
1.3
1.3
—
—
—
0
0
15
56
2.74
3.09
1.1
1.1
—
—
—
0
0
7
12
5.91
3.03
1.0
1.6
152.00
140.42
nmol/l
—
7
12
88
620
1.53
3.00
1.3
1.3
17.77
33.69
iu/ml
1.71
23
204
43
254
1.77
2.92
3.0
2.3
2.66
6.39
ug/l
2.70
37
227
23
109
2.18
2.90
4.7
3.8
0.42
0.19
g/l
0.57
14
40
7
13
5.46
2.88
3.7
6.8
—
—
—
0
0
16
65
2.52
2.82
1.5
1.7
—
—
—
0
0
8
18
4.51
2.81
1.1
1.7
—
—
—
0
0
9
23
3.98
2.79
4.3
1.5
18.72
17.21
ug/l
—
9
23
5
6
8.42
2.75
1.0
1.0
—
—
—
0
0
12
40
3.06
2.71
2.6
3.3
—
—
—
0
0
167
1357
1.39
2.65
2.1
2.0
—
—
—
0
0
7
16
4.43
2.48
4.1
1.7
17.73
15.37
nmol/l
—
7
11
83
603
1.47
2.43
6.7
3.7
252.55
175.73
ng/l
0.13
53
439
9
28
3.26
2.32
1.4
1.1
—
—
—
0
0
7
18
3.94
2.26
2.4
3.5
687.86
726.83
u/ml
—
7
18
30
175
1.77
2.16
3.0
2.8
0.31
0.16
e6/l
0.50
30
170
6
14
4.33
2.16
7.0
2.0
9.17
8.71
mmol/l
—
6
14
8
25
3.24
2.10
1.6
1.2
—
—
—
0
0
11
43
2.60
2.09
4.5
2.6
105.55
106.05
mmol/l
0.08
11
43
11
43
2.60
2.09
4.5
2.6
3.95
3.90
mmol/l
0.19
11
43
5
10
5.05
2.07
1.0
2.8
—
65.60
—
0
5
7
20
3.54
2.06
3.0
8.2
8.53
11.46
%
—
7
20
21
112
1.92
2.00
1.8
1.2
—
—
—
0
0
98
763
1.37
1.95
4.8
3.6
—
—
—
0
0
12
52
2.35
1.89
1.0
1.0
—
—
—
0
0
19
100
1.94
1.88
1.3
1.2
—
—
—
0
0
8
28
2.89
1.87
2.6
2.4
44.28
37.52
%
—
8
28
6
17
3.57
1.84
4.0
5.6
—
—
—
0
0
5
12
4.20
1.83
2.0
4.1
46.10
58.38
%
—
5
12
7
24
2.95
1.73
2.0
1.3
—
—
—
0
0
14
68
2.10
1.72
1.3
1.3
—
—
—
0
0
7
25
2.83
1.65
2.0
1.1
—
—
—
0
0
8
32
2.53
1.60
1.0
1.3
—
—
—
0
0
10
43
2.36
1.60
4.9
2.6
—
—
—
0
0
7
26
2.72
1.58
1.7
1.7
—
—
—
0
0
24
146
1.68
1.54
1.1
1.2
—
—
—
0
0
5
15
3.36
1.52
1.0
1.1
—
—
—
0
0
34
227
1.54
1.52
3.9
2.6
5.14
9.48
e9/l
0.84
29
196
6
21
2.88
1.51
1.5
1.5
—
—
—
0
0
376
3603
1.49
1.51
18.0
9.6
25.92
25.46
u/l
0.22
371
3486
118
986
1.28
1.41
1.5
1.5
—
—
—
0
0
340
3215
1.33
1.39
6.2
4.2
5.93
5.87
mmol/l
0.27
325
2965
5
17
2.96
1.36
1.6
1.3
—
—
—
0
0
20
122
1.67
1.30
1.6
1.6
—
—
—
0
0
8
35
2.31
1.27
1.0
1.0
—
—
—
0
0
38
272
1.44
1.25
1.6
1.4
—
—
—
0
0
8
37
2.18
1.22
2.0
2.7
—
—
—
0
0
5
19
2.65
1.22
2.0
1.3
—
—
—
0
0
11
57
1.96
1.18
1.1
1.2
—
—
—
0
0
42
310
1.40
1.18
3.0
3.8
6.28
43.55
ug/l
0.84
34
259
254
2342
1.22
1.17
5.3
2.9
63.97
42.75
u/l
1.24
241
2207
75
608
1.29
1.14
1.3
1.3
6.12
13.48
u/ml
0.82
27
249
10
51
1.98
1.12
1.4
1.5
—
—
—
0
0
37
270
1.41
1.11
5.3
3.4
—
—
—
0
0
5
22
2.29
1.03
2.2
7.0
—
—
—
0
0
23
155
1.51
1.03
6.0
3.4
—
—
—
0
0
24
164
1.49
1.01
2.3
2.3
—
—
—
0
0
52
408
1.31
1.01
1.5
1.5
—
—
—
0
0
0
29
0.00
0.98
0.0
1.1
—
—
—
0
0
12
69
1.76
0.97
1.2
1.4
—
—
—
0
0
370
3581
1.32
0.94
32.0
11.8
—
—
—
0
0
13
78
1.69
0.92
1.3
1.2
84.38
6.64
e6/l
—
8
61
13
78
1.69
0.92
1.5
1.3
81.88
130.09
e6/l
—
8
64
6
28
2.16
0.92
1.5
1.0
—
—
—
0
0
6
29
2.08
0.89
1.0
1.2
—
—
—
0
0
331
3170
1.22
0.87
4.8
3.7
1.42
1.26
mmol/l
1.15
302
2937
8
44
1.83
0.86
1.5
1.2
—
—
—
0
0
8
44
1.83
0.86
1.5
1.6
—
—
—
0
0
18
121
1.51
0.84
1.2
1.3
—
—
—
0
0
6
32
1.89
0.82
1.2
2.8
—
—
—
0
0
6
32
1.89
0.82
1.0
1.2
—
—
—
0
0
6
33
1.83
0.79
1.7
1.3
—
—
—
0
0
5
25
2.01
0.73
1.2
1.4
95.40
73.84
umol/l
—
5
25
15
101
1.50
0.71
1.7
2.6
—
—
—
0
0
13
85
1.55
0.69
8.2
4.3
—
—
—
0
0
5
28
1.80
0.66
1.2
1.6
108.80
184.01
pmol/l
—
5
28
5
28
1.80
0.66
1.0
1.1
—
—
—
0
0
50
417
1.23
0.64
1.7
1.5
—
—
—
0
0
284
2960
0.87
0.63
37.4
16.7
332.51
332.43
g/l
0.05
284
2941
22
165
1.35
0.62
1.2
1.1
—
—
—
0
0
8
50
1.61
0.61
1.0
1.1
—
—
—
0
0
0
20
0.00
0.60
0.0
1.0
—
258.27
—
0
11
0
22
0.00
0.59
0.0
2.6
—
—
—
0
0
6
36
1.68
0.57
1.0
1.2
—
—
—
0
0
32
258
1.26
0.56
1.7
1.4
—
—
—
0
0
339
3296
1.16
0.52
5.5
4.1
1.57
1.50
mmol/l
1.95
314
3063
11
157
0.69
0.52
1.1
1.1
—
—
—
0
0
33
400
0.81
0.52
3.0
2.8
0.99
0.77
ug/l
0.49
24
240
18
235
0.76
0.51
1.6
1.5
—
—
—
0
0
340
3310
1.15
0.50
5.5
4.1
4.70
4.72
mmol/l
0.20
314
3090
11
77
1.44
0.46
1.1
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.4
—
—
—
0
0
0
16
0.00
0.41
0.0
2.2
—
—
—
0
0
5
34
1.48
0.40
1.6
2.7
—
—
—
0
0
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
9
69
1.31
0.37
1.2
1.2
—
—
—
0
0
82
750
1.12
0.36
6.3
3.9
1.02
1.02
kg/l
0.12
14
86
385
3800
1.19
0.36
45.8
19.1
39.43
40.26
%
2.55
370
3596
7
52
1.35
0.31
1.0
1.3
8.23
16.99
u/l
—
7
44
10
75
1.34
0.30
1.2
1.8
—
—
—
0
0
81
750
1.10
0.29
1.8
1.9
—
—
—
0
0
7
56
1.25
0.29
1.4
1.2
—
—
—
0
0
5
38
1.32
0.23
1.2
1.5
—
—
—
0
0
5
38
1.32
0.23
1.6
1.3
—
—
—
0
0
14
116
1.21
0.22
13.6
10.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.9
—
—
—
0
0
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
65
608
1.08
0.20
1.7
1.6
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
23
203
1.14
0.19
7.5
2.8
—
—
—
0
0
10
81
1.24
0.19
4.7
2.7
—
—
—
0
0
341
3371
1.07
0.16
6.1
4.6
2.69
2.80
mmol/l
1.55
312
3135
9
106
0.85
0.13
1.4
1.5
—
—
—
0
0
132
1288
1.04
0.10
3.4
2.7
—
—
—
0
0
20
218
0.91
0.10
1.0
1.2
—
—
—
0
0
14
126
1.12
0.09
1.4
1.6
—
—
—
0
0
5
60
0.83
0.08
1.2
1.1
—
—
—
0
0
5
60
0.83
0.08
1.2
1.1
—
—
—
0
0
9
103
0.87
0.06
1.4
1.4
—
—
—
0
0
9
104
0.86
0.06
1.4
1.4
—
—
—
0
0
13
141
0.92
0.05
2.4
1.9
—
—
—
0
0
23
218
1.06
0.05
1.7
1.8
—
—
—
0
0
16
151
1.06
0.03
2.2
1.5
—
—
—
0
0
41
421
0.97
0.03
1.5
1.7
—
—
—
0
0
10
108
0.92
0.03
2.6
1.8
—
—
—
0
0
11
104
1.06
0.01
1.3
1.2
—
—
—
0
0
16
163
0.98
0.00
2.3
1.5
—
—
—
0
0
34
337
1.01
0.00
1.8
1.4
—
—
—
0
0
16
165
0.97
0.00
2.3
1.4
—
—
—
0
0
39
385
1.01
0.00
1.7
1.8
—
—
—
0
0
16
164
0.97
0.00
2.3
1.5
—
—
—
0
0
16
164
0.97
0.00
2.3
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
2.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
40
400
1.00
-0.00
1.3
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
3.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
3.20
—
0
9
0
9
0.00
-0.00
0.0
3.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.7
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: E4_PRIMARY_ADRENOCORTICAL_INSUFFICIENCY – Primary adrenocortical insufficiency

GWS hits: 1

This endpoint is excluded (different definition than used in FinnGen).