This is a non-core endpoint: only basic statistics are computed.
See its core counterpart C3_BILIARY_TRACT_EXALLC for full statistics.
Malignant neoplasm of other and unspecified parts of biliary tract
C3_BILIARY_TRACT
biliary tract neoplasm: A neoplasm that involves the biliary tract.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
446 |
4. Check minimum number of eventsNone |
446 |
5. Include endpointsNone |
446 |
6. Filter based on genotype QC (FinnGen only) |
446 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF9
Similar endpoints
↥List of similar endpoints to
Malignant neoplasm of other and unspecified parts of biliary tract
based on the number of shared cases.
Similar with more cases:
- Malignant neoplasm of other and unspecified parts of biliary tract, excluding all cancers (controls excluding all cancers)
- Malignant neoplasm of intrahepatic ducts, biliary tract and gallbladder
- Malignant neoplasm of intrahepatic ducts, biliary tract and gallbladder, excluding all cancers (controls excluding all cancers)
- Malignant neoplasm of digestive organs
- Malignant neoplasm of digestive organs, excluding all cancers (controls excluding all cancers)
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 446 | 181 | 265 |
| Unadjusted period prevalence (%) | 0.09 | 0.06 | 0.12 |
| Median age at first event (years) | 71.37 | 70.69 | 71.84 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 394
- Matched controls
- 3937
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
130
Kela drug reimbursment
Malignant tumour
31.2
169.1
247
201
C24.9
ICD-10 Finland
Malignant neoplasm: Biliary tract, unspecified
970.1
142.3
131
*
K83.1
ICD-10 Finland
Obstruction of bile duct
118.6
128.2
134
17
UJK02
NOMESCO Finland
ERCP
42.1
106.2
133
47
JLC30
NOMESCO Finland
Pancreatoduodenectomy
234.4
105.1
104
6
R17
ICD-10 Finland
Hyperbilirubinaemia, with or without jaundice, not elsewhere classified
56.2
101.3
119
30
JKE18
NOMESCO Finland
Endoscopic internal drainage of bile duct
140.8
100.7
104
10
D37.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Liver, gallbladder and bile ducts
57.6
88.1
103
24
A03FA01
ATC
metoclopramide; systemic, rectal
9.0
82.2
225
508
C24.1
ICD-10 Finland
Malignant neoplasm: Ampulla of Vater
+∞
81.1
75
*
8160/3-C24.9
ICD-O-3
Cholangiocarcinoma of billiary tract, NOS
+∞
81.1
75
*
C22.1
ICD-10 Finland
Malignant neoplasm: Intrahepatic bile duct carcinoma
100.9
81.0
87
11
Z51.5
ICD-10 Finland
Palliative care
14.4
75.3
137
140
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
43.1
75.1
93
28
N02AA05
ATC
oxycodone; systemic
8.4
71.5
194
409
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
20.2
70.3
109
73
C24.0
ICD-10 Finland
Malignant neoplasm: Extrahepatic bile duct
+∞
69.9
65
*
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
49.8
66.7
80
20
A04AA02
ATC
granisetron; systemic, transdermal
15.1
66.6
117
107
A09AA02
ATC
multienzymes (lipase, protease etc.)
29.9
65.6
89
38
C25.0
ICD-10 Finland
Malignant neoplasm: Head of pancreas
44.6
64.4
79
22
L01BC06
ATC
capecitabine; oral
21.3
62.2
94
57
H02AB02
ATC
dexamethasone; systemic
9.9
61.3
137
201
8140/3-C24.1
ICD-O-3
Adenocarcinoma, NOS, of ampulla of Vater
+∞
58.8
55
*
C24.09
ICD-10 Finland
Biliary duct or passage NOS
+∞
56.6
53
*
JKE02
NOMESCO Finland
Transduodenal endoscopic incision of common bile duct orifice
30.1
56.4
76
31
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
18.6
55.0
87
59
C24.00
ICD-10 Finland
Hepatic duct
+∞
53.4
50
*
WX302
NOMESCO Finland
Thoracal epidural anesthesy
13.7
52.6
95
89
C24.02
ICD-10 Finland
Common bile duct
+∞
51.2
48
*
JK3BT
NOMESCO Finland
Catherisation of bile duct with X-ray guidance
122.1
50.2
53
5
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
22.9
49.3
72
38
8160/3-C24.0
ICD-O-3
Cholangiocarcinoma of extrahepatic bile duct
+∞
49.0
46
*
8000/3-C24.9
ICD-O-3
Neoplasm, malignant of billiary tract, NOS
+∞
49.0
46
*
K83.0
ICD-10 Finland
Cholangitis
29.7
48.2
65
26
JL5SB
NOMESCO Finland
Endoscopic retrograd cholangiopancreaticography
28.0
46.7
64
27
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
24.3
43.4
62
30
8140/3-C24.0
ICD-O-3
Adenocarcinoma, NOS, of extrahepatic bile duct
+∞
41.4
39
*
8000/3-C24.0
ICD-O-3
Neoplasm, malignant of extrahepatic bile duct
+∞
38.1
36
*
JN4CD
NOMESCO Finland
Very extensive body CT
11.6
36.9
71
73
JN4BD
NOMESCO Finland
Extensive body CT
6.1
36.7
112
240
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
12.6
36.3
67
63
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
6.8
33.2
91
167
C24.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of biliary tract
+∞
32.8
31
*
JAH01
NOMESCO Finland
Laparoscopy
13.4
31.0
55
47
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
11.0
30.7
60
63
JN3BD
NOMESCO Finland
Extensive abdominal CT
5.5
30.5
100
229
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
8.0
28.7
68
100
JKE22
NOMESCO Finland
Endoscopic extraction of foreign body from bile duct
69.4
28.4
32
5
JK3NB
NOMESCO Finland
Percutaneous transhepatic cholangiography
156.1
28.0
29
*
TPH04
NOMESCO Finland
Cathetrisation of vein
3.8
27.6
143
510
R50.9
ICD-10 Finland
Fever, unspecified
4.3
27.3
117
351
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
7.3
27.0
68
109
JK3FT
NOMESCO Finland
Exchange of bile duct catheter with radiological guidance
+∞
26.3
25
*
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
15.4
26.0
43
31
JK4ZT
NOMESCO Finland
Percutaneous transhepatic implantation of bile duct prothesis
100.3
26.0
28
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
4.5
25.8
104
292
8140/3-C24.9
ICD-O-3
Adenocarcinoma, NOS, of billiary tract, NOS
+∞
24.2
23
*
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
9.1
23.8
51
63
JN4AD
NOMESCO Finland
Body CT examination
5.4
23.4
75
164
A04AA01
ATC
ondansetron; systemic, rectal
6.6
23.3
63
111
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
3.1
23.2
168
753
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.1
22.9
101
306
WZC30
NOMESCO Finland
Teaching
4.3
22.2
92
262
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
31.2
22.2
29
10
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
5.6
21.2
65
134
JN3AD
NOMESCO Finland
Abdominal CT examination
5.4
21.0
67
145
C23
ICD-10 Finland
Malignant neoplasm of gallbladder
81.3
20.9
23
*
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
7.0
20.4
52
84
JKE32
NOMESCO Finland
Endoscopic dilatation of bile duct
50.9
20.4
24
5
B01AB10
ATC
tinzaparin; parenteral
5.6
19.1
58
118
D37.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Digestive organ, unspecified
40.6
18.8
23
6
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
7.4
18.7
45
67
C25.9
ICD-10 Finland
Malignant neoplasm: Pancreas, unspecified
20.6
18.5
27
14
K83.9
ICD-10 Finland
Disease of biliary tract, unspecified
46.4
18.4
22
5
C22.9
ICD-10 Finland
Malignant neoplasm: Liver, unspecified
23.1
18.4
26
12
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
11.5
18.3
34
32
R4190
NOMESCO Finland
Nutritional therapy
10.0
18.1
36
39
B01AB05
ATC
enoxaparin; parenteral
2.7
18.0
166
835
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
8.5
17.8
39
50
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
14.0
17.7
30
23
TPH07
NOMESCO Finland
Cathetrisation of artery
3.8
16.3
74
225
C78.6
ICD-10 Finland
Secondary malignant neoplasm of retroperitoneum and peritoneum
27.6
15.8
21
8
TPX10
NOMESCO Finland
Implantation of vascular injection port
8.5
15.2
33
42
A06AH03
ATC
naloxegol; oral
14.9
14.7
24
17
JKE25
NOMESCO Finland
Endoscopic external drainage of bile duct
83.3
14.7
16
*
A04AA55
ATC
palonosetron, combinations; systemic
8.9
14.3
30
36
WX402
NOMESCO Finland
General anaesthesia
3.3
14.3
80
286
J01MA12
ATC
levofloxacin; systemic
2.7
14.0
115
526
C24.01
ICD-10 Finland
Cystic duct
+∞
13.6
13
*
JK3NT
NOMESCO Finland
Percutaneous transhepatic dilatation of bileducts
144.8
13.5
14
*
A02BC02
ATC
pantoprazole; systemic
2.3
12.9
273
1963
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
12.2
12.5
22
19
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
5.8
12.4
35
65
JAH00
NOMESCO Finland
Laparotomy
6.5
12.4
32
53
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
10.5
12.2
23
23
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.8
12.0
83
339
C17.0
ICD-10 Finland
Malignant neoplasm: Duodenum
67.0
11.7
13
*
R18
ICD-10 Finland
Ascites
9.3
11.4
23
26
E13.9
ICD-10 Finland
Other specified diabetes mellitus, without complications
36.2
11.3
14
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.3
11.2
123
647
A05AA02
ATC
ursodeoxycholic acid; oral
11.0
10.9
20
19
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.6
10.7
89
403
JKA20
NOMESCO Finland
Cholecystectomy
6.2
10.6
28
48
D77
ICPC
Malignant digestive neopl other/NOS
16.6
10.4
16
10
JDE00
NOMESCO Finland
Gastrojejunostomy
33.5
10.4
13
*
UJK12
NOMESCO Finland
Peroral cholangioscopy
24.1
10.3
14
6
WX004
NOMESCO Finland
Patient-controlled sedation
24.1
10.3
14
6
A06AD11
ATC
lactulose; oral
2.4
10.2
101
499
C22.0
ICD-10 Finland
Malignant neoplasm: Liver cell carcinoma
11.7
10.2
18
16
JK3SB
NOMESCO Finland
Endoscopic retrorade cholangiography
41.2
10.0
12
*
WW500
NOMESCO Finland
Blood transfusion
4.9
9.6
31
68
D76
ICPC
Malignant neoplasm pancreas
102.4
9.5
10
*
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
6.5
9.2
23
37
K90.3
ICD-10 Finland
Pancreatic steatorrhoea
19.1
9.0
13
7
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.4
8.8
84
403
A98
ICPC
Health maint/preventive medicine
0.5
8.8
241
2981
R93.2
ICD-10 Finland
Abnormal findings on diagnostic imaging of liver and biliary tract
51.1
8.7
10
*
JKC30
NOMESCO Finland
Partial excision of bile duct and anastomosis to jejunum
+∞
8.4
8
*
A04AD12
ATC
aprepitant; systemic
6.7
8.3
20
31
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
22.6
8.1
11
5
C77.2
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Intra-abdominal lymph nodes
15.4
7.8
12
8
WB121
NOMESCO Finland
Demanding neoadjuvant cytostatic therapy
15.4
7.8
12
8
K80.5
ICD-10 Finland
Calculus of bile duct without cholangitis or cholecystitis
4.7
7.7
25
56
XJD02
NOMESCO Finland
Peroral endoscopic ultrasonography
12.2
7.6
13
11
8160/3-C22.1
ICD-O-3
Cholangiocarcinoma of intrahepatic bile duct
25.6
7.6
10
*
K76.9
ICD-10 Finland
Liver disease, unspecified
10.3
7.6
14
14
ZXE40
NOMESCO Finland
More than seven and less than nine hours
5.8
7.5
20
36
K85.8
ICD-10 Finland
Other acute pancreatitis
13.7
7.4
12
9
JKE12
NOMESCO Finland
Endoscopic extraction of calculus from bile duct
7.1
7.4
17
25
JK3MB
NOMESCO Finland
Postoperative cholangiography
+∞
7.3
7
*
WX892
NOMESCO Finland
Monitored bed care
2.8
7.1
45
174
WX725
NOMESCO Finland
Noninvasive ventilation
3.9
6.9
27
73
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.1
6.9
36
123
ZX120
NOMESCO Finland
Intravenous
2.6
6.7
49
204
JA3BT
NOMESCO Finland
Cathetrisation of abdominal cavity with X-ray guidance
23.0
6.7
9
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
4.8
6.7
21
46
K83.8
ICD-10 Finland
Other specified diseases of biliary tract
71.0
6.4
7
*
JL5CG
NOMESCO Finland
Extensive MRI examinaiton of bile and pancreas ducts with high intesity magnet
14.6
6.4
10
7
XX3DW
NOMESCO Finland
Time consuming IT work
2.5
6.4
51
225
8163/3-C24.1
ICD-O-3
Pancreatobiliary type carcinoma of ampulla of Vater
+∞
6.3
6
*
C25.7
ICD-10 Finland
Malignant neoplasm: Other parts of pancreas
+∞
6.3
6
*
D13
ICPC
Jaundice
+∞
6.3
6
*
WX002
NOMESCO Finland
Sedation and analgesia
2.0
6.2
86
486
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
4.7
6.1
19
42
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: C3_BILIARY_TRACT – Malignant neoplasm of other and unspecified parts of biliary tract
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).