Acute myeloid leukaemia and myelodysplastic syndromes

C3_AML_MDS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

None

0 out of 7 registries used, show all original rules.

0

4. Check minimum number of events

None

0

5. Include endpoints

644

6. Filter based on genotype QC (FinnGen only)

644

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF12

Similar endpoints

List of similar endpoints to Acute myeloid leukaemia and myelodysplastic syndromes based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

No data for upset plot.

No data for upset table.

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 644 251 393
Unadjusted period prevalence (%) 0.14 0.09 0.17
Median age at first event (years) 72.44 70.30 73.81

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
210
50
61.84
307.65
1.4
1.1
—
—
—
0
0
204
85
34.66
299.38
5.5
1.4
—
—
—
0
0
109
31
42.12
177.17
1.3
1.3
—
—
—
0
0
109
34
38.39
172.57
2.7
2.5
—
—
—
0
0
121
52
28.42
172.44
1.7
1.2
—
—
—
0
0
118
58
24.68
159.25
1.5
1.6
104.3
97.2
u/ml
0.26
33
11
302
659
7.75
146.56
8.0
2.4
1.9
1.8
%
0.68
281
594
115
68
20.37
142.66
1.3
1.6
—
—
—
0
0
111
65
20.43
138.21
1.4
1.3
255.8
273.9
u/ml
0.12
71
34
146
140
13.19
138.21
1.9
1.6
—
—
—
0
0
251
477
7.98
138.16
7.7
2.4
68.7
67.6
e9/l
0.06
208
390
125
96
15.92
135.27
1.4
1.4
—
—
—
0
0
111
78
16.99
125.86
1.3
1.1
169.6
43.4
u/l
3.15
92
68
209
381
7.64
117.97
11.6
3.9
1.8
0.8
%
2.41
136
116
105
75
16.53
117.81
10.3
3.4
1.2
1.6
%
0.24
86
63
169
270
8.13
106.95
2.0
1.8
1.3
1.6
g/l
2.82
144
236
87
58
17.19
100.87
1.2
1.0
—
—
—
0
0
176
312
7.39
100.87
3.4
2.5
10.0
10.4
g/l
0.53
166
283
57
14
44.57
95.04
4.7
2.4
—
—
—
0
0
55
14
42.86
90.85
4.5
1.3
—
—
—
0
0
79
60
14.87
85.03
1.2
1.1
—
—
—
0
0
138
231
7.33
82.56
1.4
1.3
—
—
—
0
0
170
357
6.11
81.02
12.1
4.0
0.2
0.1
%
0.75
123
107
142
254
6.89
79.60
1.5
1.6
1.2
1.5
g/l
0.73
136
231
164
342
6.09
78.58
12.0
3.8
1.1
0.4
%
2.95
83
88
74
59
14.04
77.30
12.3
3.9
—
—
—
0
0
78
68
12.91
77.17
8.7
5.6
10.5
12.6
mg/l
2.50
73
62
67
48
15.46
74.31
10.3
3.0
43.1
54.0
%
1.46
40
36
164
378
5.48
69.84
1.6
1.5
—
—
—
0
0
65
51
14.06
68.38
2.3
1.6
—
—
—
0
0
65
51
14.06
68.38
2.3
1.6
—
—
—
0
0
65
51
14.06
68.38
2.3
1.6
—
—
—
0
0
65
51
14.06
68.38
2.3
1.6
—
—
—
0
0
176
448
5.03
66.48
2.6
2.5
66.0
65.7
g/l
0.20
166
405
151
338
5.53
66.24
12.0
4.0
4.2
0.1
%
2.30
93
92
70
7
112.00
65.31
1.0
1.0
—
—
—
0
0
70
7
112.00
65.31
1.4
1.0
—
—
—
0
0
167
424
4.97
63.01
1.6
1.5
—
—
—
0
0
214
663
4.34
62.51
12.9
5.4
1.1
1.0
mmol/l
1.26
205
601
39
12
34.53
60.83
1.2
1.0
—
—
—
0
0
334
1497
3.56
55.30
26.9
5.3
—
—
—
0
0
57
53
11.70
53.75
1.2
1.2
—
—
—
0
0
169
511
4.13
49.92
1.6
1.7
—
—
—
0
0
216
777
3.68
49.53
11.6
3.3
0.8
0.8
mmol/l
0.56
203
720
42
27
16.57
48.99
7.1
1.6
356.7
714.9
e6/l
1.09
21
14
280
1233
3.25
45.75
8.6
2.8
329.5
9433.8
umol/l
6.44
267
1033
134
371
4.30
44.23
2.0
2.3
—
—
—
0
0
41
33
13.20
42.16
7.6
1.5
1.0
1.0
e9/l
0.06
21
15
368
2024
2.91
38.56
23.9
5.5
0.6
0.6
%
0.18
354
1875
376
2095
2.91
38.38
26.6
5.7
10.8
8.8
%
4.70
360
1948
373
2085
2.87
37.58
24.9
5.5
1.9
2.8
%
8.20
358
1928
378
2139
2.86
37.00
25.8
5.7
32.7
26.0
%
13.09
361
1977
202
817
3.15
36.90
5.0
2.1
29.2
30.0
s
0.96
193
787
301
1587
2.68
32.69
17.0
4.2
—
—
—
0
0
37
6
65.27
32.39
1.2
1.0
—
—
—
0
0
30
24
13.06
30.82
2.1
2.7
37.2
42.2
%
—
11
10
359
2104
2.60
30.79
22.9
5.5
47.7
58.6
%
27.14
341
1956
28
20
14.59
30.67
2.9
1.7
20.7
16.8
%
—
13
10
134
470
3.34
30.54
8.5
6.7
9.1
11.3
mmol/l
2.17
128
445
29
0
+∞
30.45
1.0
0.0
—
—
—
0
0
290
1544
2.60
30.30
18.6
2.5
—
—
—
0
0
28
0
+∞
29.39
1.0
0.0
—
—
—
0
0
28
0
+∞
29.39
1.0
0.0
—
—
—
0
0
28
0
+∞
29.39
1.0
0.0
—
—
—
0
0
28
0
+∞
29.39
1.0
0.0
—
—
—
0
0
87
237
4.09
28.81
2.4
1.8
6.5
2.9
ug/l
0.48
75
209
55
110
5.37
26.57
1.3
2.0
31.3
12.7
mg/l
1.03
47
99
228
1138
2.55
26.57
16.5
2.4
—
—
—
0
0
43
68
6.70
26.39
6.0
1.5
33.1
32.7
pg
0.18
43
68
22
14
16.23
25.50
1.1
1.1
—
—
—
0
0
364
2294
2.35
24.62
25.0
5.5
0.1
0.2
e9/l
15.55
323
2023
171
767
2.67
24.57
1.5
1.3
2.4
2.6
g/l
0.81
144
450
28
29
10.05
24.26
1.3
1.1
—
—
—
0
0
23
0
+∞
24.11
1.8
0.0
20.2
—
%
—
23
0
30
9
34.87
23.53
1.3
1.6
—
—
—
0
0
346
2170
2.28
23.19
27.3
4.2
—
—
—
0
0
20
13
15.85
22.88
2.1
1.2
—
—
—
0
0
176
837
2.52
22.15
2.1
2.4
18.3
12.1
umol/l
11.18
169
766
348
2217
2.24
22.08
21.1
5.3
0.7
0.6
e9/l
0.46
316
1909
348
2225
2.23
21.78
21.2
5.3
0.0
0.0
e9/l
5.92
315
1926
65
175
4.02
21.74
2.1
3.5
57.5
99.0
mg/l
0.54
57
141
352
2268
2.22
21.53
21.8
5.4
1.8
1.9
e9/l
0.23
323
2006
184
910
2.43
21.15
17.1
4.6
—
—
—
0
0
104
389
3.00
20.81
1.8
1.4
—
—
—
0
0
63
172
3.95
20.65
2.1
3.4
9.5
2.1
ratio
—
5
19
52
124
4.47
20.37
2.4
3.7
—
—
—
0
0
157
737
2.49
20.11
2.1
2.4
37.9
21.6
%
11.33
127
631
162
776
2.45
19.83
2.0
2.4
2.0
2.3
g/l
11.68
154
707
383
2606
2.16
19.73
48.8
8.5
3.3
4.3
e9/l
1.34
357
2283
192
997
2.32
19.54
2.8
1.7
3.8
1.4
mg/l
2.57
167
783
62
175
3.81
19.38
2.1
3.5
73.8
34.0
mg/l
0.42
53
144
64
193
3.57
18.14
1.6
2.4
11.7
10.1
g/l
1.10
56
167
153
750
2.36
17.58
2.1
2.0
—
—
—
0
0
17
14
12.44
16.97
1.0
1.1
—
—
—
0
0
297
1928
2.00
16.31
4.8
2.6
730.2
150.1
ug/l
7.30
272
1738
15
11
13.94
15.96
1.0
1.2
—
—
—
0
0
360
2547
1.94
14.91
27.0
5.9
13.2
12.3
umol/l
0.66
349
2400
202
1175
2.05
14.80
2.1
1.8
1279.2
1187.7
nmol/l
0.58
166
879
355
2529
1.90
14.09
17.3
6.5
1.2
1.2
mmol/l
1.27
297
2100
330
2297
1.90
14.07
15.0
5.9
1.2
1.2
mmol/l
2.95
301
2057
13
0
+∞
13.59
1.2
0.0
—
—
—
0
0
187
1089
2.01
13.47
2.3
1.3
—
—
—
0
0
225
1402
1.93
13.28
2.6
2.2
3.0
3.3
mg/l
0.78
187
1196
31
69
4.67
13.20
1.1
1.3
81.9
307.4
miu/ml
—
5
24
52
173
3.18
12.59
1.7
2.5
36.6
36.8
g/l
0.05
45
147
29
65
4.62
12.24
2.7
1.2
—
—
—
0
0
17
9
19.35
11.63
3.2
1.4
—
—
—
0
0
16
21
7.79
11.46
1.4
1.2
—
—
—
0
0
307
2187
1.77
11.29
15.6
4.5
32.3
34.6
g/l
7.29
287
2020
18
29
6.36
10.78
2.3
1.7
—
—
—
0
0
187
1179
1.83
10.18
12.8
3.9
81.2
84.4
%
0.98
181
1149
228
1528
1.76
10.08
14.8
3.9
7.4
7.4
ph
2.16
39
293
344
4266
0.58
10.00
4.4
5.1
2.4
2.6
mmol/l
2.87
305
3824
39
128
3.18
9.67
1.3
1.6
—
—
—
0
0
11
11
10.16
9.56
1.4
1.0
—
—
—
0
0
30
84
3.70
9.49
10.5
3.2
46.6
60.2
%
3.90
30
84
98
508
2.10
9.43
3.3
1.4
—
—
—
0
0
23
53
4.46
9.40
3.2
2.1
2.6
6249.6
u/l
—
5
15
328
4080
0.60
9.13
5.6
6.4
40.3
41.2
mmol/mol
0.85
295
3708
10
10
10.14
8.66
1.2
1.6
—
—
—
0
0
16
29
5.63
8.53
2.6
1.2
—
—
—
0
0
336
4097
0.62
7.87
4.1
4.5
1.3
1.4
mmol/l
7.74
295
3673
345
4141
0.64
7.04
4.5
4.6
4.1
4.4
mmol/l
6.10
305
3744
101
585
1.86
7.01
2.0
1.8
—
—
—
0
0
22
63
3.58
6.77
3.0
1.3
15.8
8.6
u/l
0.60
17
54
83
456
1.94
6.75
2.0
2.3
0.2
0.2
g/l
0.03
73
422
169
1155
1.63
6.48
38.0
6.2
—
—
—
0
0
62
1132
0.50
6.43
3.0
3.3
0.9
0.9
ug/l
0.05
39
794
10
15
6.76
6.33
1.1
1.1
—
—
—
0
0
16
38
4.29
6.32
1.2
1.1
—
—
—
0
0
424
4821
0.65
6.09
85.2
24.9
9.4
6.9
e9/l
0.76
405
4662
424
4820
0.65
6.07
85.9
25.1
105.7
132.6
g/l
92.02
409
4714
424
4819
0.65
6.05
84.8
24.8
31.2
30.4
pg
11.05
411
4716
424
4819
0.65
6.05
85.2
24.9
3.5
4.4
e12/l
80.74
404
4660
424
4818
0.65
6.03
85.4
24.9
160.6
239.3
e9/l
32.12
403
4677
84
481
1.86
6.02
9.5
4.4
—
—
—
0
0
14
31
4.59
6.01
3.0
1.3
—
—
—
0
0
424
4817
0.65
6.01
85.0
24.9
94.6
91.6
fl
16.95
411
4717
396
4559
0.66
5.94
46.4
16.4
—
—
—
0
0
49
234
2.18
5.81
1.5
1.3
—
—
—
0
0
360
4211
0.67
5.70
5.4
4.9
6.1
6.1
mmol/l
0.04
311
3750
23
76
3.10
5.70
1.5
1.5
—
—
—
0
0
75
1243
0.55
5.60
3.5
3.1
—
—
—
0
0
84
501
1.78
5.28
1.3
1.3
560.0
447.9
titre
0.29
23
116
407
4623
0.67
5.24
36.9
10.7
27.0
24.7
u/l
1.89
387
4427
337
3958
0.69
5.13
4.8
4.1
1.4
1.3
mmol/l
3.64
300
3529
276
2209
1.44
4.76
8.8
11.8
1.3
1.3
inr
0.27
66
638
20
69
2.96
4.64
2.8
1.4
10.9
25.8
iu/l
2.23
14
63
269
2154
1.43
4.58
2.6
2.1
87.4
92.8
pmol/l
1.25
184
1131
11
25
4.46
4.57
1.4
1.0
28.4
52.1
mg/l
0.81
11
19
265
3202
0.71
4.40
6.1
4.3
—
—
—
0
0
345
2901
1.41
4.38
12.9
4.8
6.9
6.9
mmol/l
0.18
334
2731
345
3986
0.71
4.36
5.2
4.6
2.0
2.0
mu/l
0.19
305
3539
9
12
7.59
4.36
1.2
1.0
—
—
—
0
0
21
78
2.75
4.29
2.0
3.3
—
—
—
0
0
14
41
3.47
4.20
1.1
1.0
—
—
—
0
0
141
1014
1.50
4.15
4.4
4.0
93.7
295.4
ng/l
2.05
123
867
67
402
1.74
4.14
2.3
2.0
376.1
368.6
nmol/l
0.11
67
366
12
32
3.80
4.10
8.8
3.6
—
—
—
0
0
42
218
1.99
4.06
6.5
5.0
25.4
25.0
mmol/l
0.36
37
208
17
59
2.93
3.92
1.1
1.1
—
—
—
0
0
7
8
8.83
3.78
1.0
1.0
14.5
18.2
umol/l
—
7
8
80
517
1.63
3.76
3.2
3.0
301.2
272.7
ng/l
0.25
73
479
26
115
2.31
3.76
2.0
1.7
13048.5
21398.0
e6/l
0.60
20
84
418
4636
0.72
3.74
59.4
20.6
4.0
4.0
mmol/l
0.13
405
4493
15
50
3.05
3.71
1.1
1.1
—
—
—
0
0
153
1985
0.70
3.63
4.5
5.5
2.3
3.7
ug/l
2.40
134
1738
79
517
1.60
3.53
4.3
4.2
1.3
1.9
mmol/l
0.54
63
397
419
4631
0.73
3.53
53.1
20.5
138.6
139.6
mmol/l
9.70
403
4487
38
202
1.94
3.47
1.5
1.5
—
—
—
0
0
8
14
5.77
3.35
5.1
2.3
20.4
10.4
mu/l
—
8
14
46
267
1.78
3.22
5.8
4.4
—
—
—
0
0
11
33
3.37
3.20
1.1
1.2
—
—
—
0
0
30
151
2.03
3.20
5.7
3.5
—
—
—
0
0
191
1523
1.36
3.09
3.5
2.4
48.3
56.9
u/l
3.51
171
1411
113
1506
0.70
3.04
3.4
4.0
10.2
9.9
mg/mmol
0.02
73
964
310
3543
0.76
3.02
80.4
22.7
330.4
331.5
g/l
1.09
304
3503
6
193
0.30
2.99
2.0
2.0
—
—
—
0
0
29
150
1.98
2.89
1.3
1.2
—
—
—
0
0
18
383
0.45
2.88
1.6
1.6
—
—
—
0
0
57
363
1.63
2.87
5.5
4.2
5.2
5.2
kpa
0.06
48
336
10
31
3.26
2.78
1.6
1.2
—
—
—
0
0
56
359
1.61
2.75
5.4
4.3
7.4
7.4
ph
—
5
35
24
118
2.07
2.75
1.5
1.2
—
—
—
0
0
17
72
2.40
2.74
1.6
1.5
—
—
—
0
0
114
850
1.41
2.74
4.9
3.2
2.8
2.3
e6/l
0.19
66
510
88
626
1.47
2.72
7.0
7.0
1.1
1.4
mmol/l
0.17
70
481
6
10
6.04
2.70
3.5
1.5
—
—
—
0
0
88
628
1.46
2.67
6.1
6.9
10.6
11.5
kpa
1.08
83
601
44
267
1.70
2.67
8.7
9.8
—
—
—
0
0
107
1410
0.71
2.66
2.6
3.2
1233.6
217.6
mg/l
0.66
76
924
81
570
1.48
2.64
7.2
7.2
93.5
95.1
%
0.71
76
545
60
397
1.56
2.60
4.9
4.2
—
—
—
0
0
112
1459
0.72
2.59
2.6
3.1
6.7
7.2
mmol/l
0.51
99
1189
5
7
7.19
2.55
1.8
1.6
—
—
—
0
0
25
130
1.96
2.48
1.5
1.4
0.2
0.2
g/l
0.49
25
125
8
21
3.84
2.47
1.3
1.1
—
—
—
0
0
199
1650
1.30
2.38
4.8
3.6
—
—
—
0
0
7
17
4.15
2.36
1.0
1.1
107.1
125.0
nmol/l
—
7
17
45
286
1.62
2.32
3.8
2.9
3.9
4.1
e9/l
0.10
33
212
25
135
1.89
2.25
1.5
1.4
1.2
1.1
g/l
0.14
25
129
287
3242
0.79
2.23
4.5
3.7
14.8
15.0
pmol/l
0.44
255
2857
5
150
0.33
2.17
2.8
1.4
—
—
—
0
0
207
1746
1.27
2.13
3.5
3.3
2188.5
2113.0
ng/l
0.08
193
1522
15
68
2.23
2.12
2.7
3.1
—
—
—
0
0
9
32
2.84
2.00
1.0
1.2
—
—
—
0
0
12
51
2.38
1.96
9.0
3.7
—
—
—
0
0
9
33
2.75
1.93
1.0
1.6
—
—
—
0
0
61
838
0.70
1.92
1.3
1.2
4.5
1.4
u/ml
0.47
14
219
15
290
0.51
1.89
6.1
4.2
—
—
—
0
0
19
339
0.55
1.86
2.4
3.6
—
—
—
0
0
6
17
3.55
1.84
11.7
1.4
—
—
—
0
0
229
1990
1.23
1.77
40.3
10.0
0.2
0.0
e9/l
0.60
194
1626
198
1695
1.24
1.75
5.0
3.3
2.3
2.3
mmol/l
4.31
171
1449
190
1625
1.24
1.69
5.3
3.5
225.4
130.0
e6/l
0.26
155
1297
59
430
1.41
1.66
4.0
3.7
—
—
—
0
0
59
432
1.40
1.62
9.2
8.7
—
—
—
0
0
157
1324
1.25
1.58
1.9
1.6
19.8
20.1
nmol/l
0.12
147
1111
419
4468
0.82
1.57
62.6
17.2
35.0
27.0
mg/l
3.75
393
3692
162
1374
1.24
1.55
5.4
3.3
—
—
—
0
0
7
27
2.61
1.52
1.9
1.6
—
—
—
0
0
7
27
2.61
1.52
1.6
1.2
3.3
1.9
mmol/l
—
7
27
350
3219
1.19
1.42
6.9
5.1
226.2
3519.3
e6/l
—
10
69
9
41
2.21
1.37
4.4
2.7
—
—
—
0
0
389
3617
1.19
1.37
32.1
7.3
83.6
82.6
u/l
0.19
375
3357
6
23
2.62
1.37
1.2
1.4
—
—
—
0
0
6
24
2.51
1.30
1.0
1.7
—
—
—
0
0
13
70
1.87
1.24
1.3
1.4
—
—
—
0
0
20
125
1.62
1.19
5.4
3.7
—
—
—
0
0
8
38
2.12
1.18
2.1
1.1
—
—
—
0
0
8
38
2.12
1.18
2.1
1.1
—
—
—
0
0
8
39
2.06
1.15
1.0
1.3
—
—
—
0
0
166
1456
1.19
1.12
5.4
3.4
0.5
0.6
e6/l
0.51
131
1136
8
41
1.96
1.09
1.4
1.4
—
—
—
0
0
11
192
0.57
1.07
1.3
1.4
—
—
—
0
0
129
1115
1.20
1.03
4.4
3.0
540.7
563.7
mosm/kgh2o
0.72
120
944
30
214
1.42
1.01
6.1
4.6
—
—
—
0
0
11
61
1.82
0.99
1.5
1.3
—
—
—
0
0
361
3827
0.87
0.97
59.9
18.6
31.7
38.6
%
23.76
207
2457
0
30
0.00
0.97
0.0
1.5
—
—
—
0
0
202
1824
1.16
0.95
6.3
4.0
77.2
172.5
e6/l
1.13
160
1376
40
305
1.33
0.93
10.1
9.3
0.7
0.7
%
0.19
40
300
9
52
1.74
0.92
1.6
2.1
—
—
—
0
0
42
324
1.32
0.90
2.7
2.9
1.0
0.3
e6/l
0.55
42
317
6
30
2.01
0.87
2.2
1.4
55.7
68.1
%
—
6
19
131
1154
1.17
0.85
1.6
1.8
120388868.5
6090174.9
pmol/l
0.46
103
936
6
31
1.94
0.84
1.0
1.3
—
—
—
0
0
29
214
1.37
0.84
1.4
1.3
—
—
—
0
0
6
114
0.52
0.83
1.0
1.1
—
—
—
0
0
8
46
1.75
0.82
1.5
1.2
—
—
—
0
0
131
1157
1.17
0.82
3.9
2.7
5.6
4.5
e6/l
1.07
122
1018
40
312
1.30
0.81
10.0
9.0
1.5
1.4
%
0.17
40
307
14
212
0.65
0.81
2.9
3.3
10.7
14408.2
u/ml
0.60
14
176
109
1242
0.85
0.79
4.0
3.9
—
—
—
0
0
8
48
1.67
0.79
2.3
1.3
30444.9
240368.5
e6/l
—
8
34
69
580
1.21
0.76
1.3
1.2
—
—
—
0
0
0
28
0.00
0.76
0.0
1.4
—
—
—
0
0
0
28
0.00
0.76
0.0
1.4
—
—
—
0
0
5
27
1.86
0.68
2.4
1.3
1.8
1.5
%
—
5
20
12
78
1.55
0.66
1.5
1.5
—
—
—
0
0
5
30
1.67
0.61
4.6
16.1
—
—
—
0
0
209
2242
0.90
0.61
6.3
5.7
0.0
0.0
estimate
0.00
39
429
18
131
1.38
0.59
1.3
1.3
—
1.6
—
0
12
23
175
1.33
0.59
3.8
3.3
30.0
62.9
u/ml
0.76
23
166
21
274
0.76
0.57
1.3
1.2
—
—
—
0
0
213
2272
0.91
0.55
4.5
4.3
0.0
0.0
estimate
0.00
36
429
6
39
1.54
0.53
3.0
2.1
—
—
—
0
0
6
40
1.50
0.51
1.0
2.0
7.8
10.5
%
—
6
40
10
145
0.68
0.51
17.0
12.9
—
—
—
0
0
38
453
0.83
0.50
1.3
1.3
—
—
—
0
0
53
611
0.86
0.48
1.2
1.3
1.0
13.0
u/ml
3.98
14
227
56
487
1.16
0.47
2.5
2.7
3.3
6.2
ug/l
2.23
44
425
219
2066
1.09
0.47
4.1
4.3
31.4
48.5
ng/l
2.76
170
1574
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
14
183
0.76
0.41
1.1
1.1
—
32.2
titre
—
0
5
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
1.4
—
—
—
0
0
21
170
1.24
0.37
6.3
3.8
3.7
3.9
mmol/l
0.94
21
152
214
2246
0.93
0.37
4.5
4.2
0.0
0.0
estimate
0.00
42
439
16
126
1.28
0.35
1.3
1.4
247.3
281.0
ug/g
0.30
11
75
6
43
1.40
0.35
1.8
1.2
—
—
—
0
0
6
43
1.40
0.35
1.3
1.4
—
—
—
0
0
6
86
0.69
0.33
2.0
1.4
—
—
—
0
0
6
86
0.69
0.33
2.0
1.4
—
—
—
0
0
87
802
1.10
0.32
18.9
29.2
1.3
1.5
inr
0.43
15
100
348
3381
1.06
0.32
5.2
4.1
26.0
14.3
mm/h
13.36
320
3069
54
599
0.89
0.31
1.7
1.3
—
—
—
0
0
59
645
0.91
0.27
1.1
1.3
15.2
37.1
iu/ml
3.98
17
210
14
113
1.24
0.27
2.6
2.2
15.0
15.7
%
—
6
51
31
273
1.14
0.25
3.1
2.6
—
—
—
0
0
11
87
1.27
0.24
1.1
1.3
—
—
—
0
0
159
1522
1.06
0.24
2.6
2.1
120.0
343.0
u/l
2.59
146
1419
17
143
1.19
0.23
2.2
3.3
0.8
0.9
nmol/l
0.71
12
115
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
3.3
—
0
14
97
1020
0.94
0.19
3.2
3.2
2.4
2.5
mmol/l
0.86
87
887
13
109
1.20
0.18
1.5
2.9
—
—
—
0
0
7
60
1.17
0.18
1.0
1.1
—
—
—
0
0
24
214
1.13
0.17
1.5
1.2
—
—
—
0
0
7
61
1.15
0.17
2.3
2.1
—
—
—
0
0
10
82
1.22
0.17
1.5
2.3
53.9
59.8
%
—
10
82
5
68
0.73
0.17
1.0
1.1
—
—
—
0
0
27
298
0.90
0.16
1.6
1.4
—
—
—
0
0
11
130
0.84
0.16
1.8
1.6
—
—
—
0
0
6
78
0.77
0.15
2.5
2.8
—
—
—
0
0
108
1041
1.05
0.14
4.6
4.2
—
—
—
0
0
12
104
1.16
0.12
2.6
2.4
—
—
—
0
0
16
179
0.89
0.12
5.2
5.1
—
—
—
0
0
98
1014
0.96
0.11
4.5
4.8
1.0
1.0
kg/l
0.25
15
153
5
44
1.14
0.10
1.4
1.1
—
—
—
0
0
5
44
1.14
0.10
3.0
1.3
16.5
25.2
%
—
5
34
146
1493
0.97
0.09
4.8
4.3
—
—
—
0
0
5
47
1.06
0.09
4.0
3.1
6.9
7.2
nmol/l
—
5
47
7
84
0.83
0.07
1.9
1.4
—
—
—
0
0
7
85
0.82
0.07
2.0
1.4
—
—
—
0
0
8
93
0.86
0.06
3.4
2.7
—
—
—
0
0
27
257
1.05
0.05
2.3
2.7
0.7
0.7
%
0.34
27
252
174
1762
0.98
0.05
2.6
2.2
—
—
—
0
0
12
130
0.92
0.04
2.5
2.4
65.7
98.4
ug/min
—
6
78
126
1273
0.99
0.03
4.4
4.5
0.0
0.0
estimate
0.00
35
418
24
231
1.04
0.03
1.0
1.3
—
—
—
0
0
36
351
1.03
0.02
1.7
1.5
—
—
—
0
0
18
188
0.96
0.02
1.6
3.2
0.2
0.3
g/l
—
7
72
41
401
1.02
0.02
4.6
3.9
—
—
—
0
0
12
127
0.94
0.01
1.3
1.1
—
—
—
0
0
15
143
1.05
0.01
1.1
1.1
—
—
—
0
0
325
3241
1.01
0.01
6.7
4.6
—
—
—
0
0
25
246
1.02
0.00
2.3
3.0
—
—
—
0
0
44
437
1.01
0.00
1.7
2.0
106.5
138.0
ug/g
0.76
35
345
56
558
1.00
0.00
2.9
4.0
3.5
34.5
ug/l
1.43
45
476
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
7.8
—
—
—
0
0
0
8
0.00
0.00
0.0
2.9
—
9112.3
—
0
8
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
0.1
—
0
5
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
4.3
—
5.4
—
0
7
0
6
0.00
0.00
0.0
2.2
—
16.4
—
0
6
5
51
0.98
0.00
3.0
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
0.00
0.0
3.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: C3_AML_MDS – Acute myeloid leukaemia and myelodysplastic syndromes

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).