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Acute myeloid leukaemia and myelodysplastic syndromes

Endpoint Browser PheWeb

C3_AML_MDS

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

None

0 out of 7 registries used, show all original rules.

0

4. Check minimum number of events

None

0

5. Include endpoints

783

6. Filter based on genotype QC (FinnGen only)

733

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

First used in FinnGen datafreeze
DF12

Case counts by codes

↥

FinnGen case counts by registry codes:

No data for upset plot.

No data for upset table.

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 733 283 450
Unadjusted period prevalence (%) 0.17 0.10 0.21
Median age at first event (years) 73.86 72.17 74.92

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
783
Matched controls
7830
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
A04AA01
ATC
ondansetron; systemic, rectal
43.7
322.5
200
61
9861/3-C42.1
ICD-O-3
Acute myeloid leukemia, NOS, of bone marrow
+∞
312.0
278
*
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
266.0
307.7
494
50
WW500
NOMESCO Finland
Blood transfusion
74.5
307.7
295
63
XW000
NOMESCO Finland
Bone marrow biopsy
95.8
307.7
419
93
C92.0
ICD-10 Finland
Acute myeloblastic leukaemia [AML]
+∞
307.7
379
*
D46.9
ICD-10 Finland
Myelodysplastic syndrome, unspecified
663.3
287.1
267
6
9989/3-C42.1
ICD-O-3
Myelodysplastic syndrome, NOS, of bone marrow
+∞
256.8
232
*
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
31.3
212.8
144
56
D64.9
ICD-10 Finland
Anaemia, unspecified
9.4
207.1
340
591
D46.7
ICD-10 Finland
Other myelodysplastic syndromes
375.1
203.7
197
7
127
Kela drug reimbursment
Transplant complication
68.8
185.7
102
17
B03XA02
ATC
darbepoetin alfa; parenteral
31.4
176.1
118
44
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
27.9
173.0
121
51
D70.89
ICD-10 Finland
Neutropenic splenomegaly
85.7
171.5
91
12
L03AA02
ATC
filgrastim; parenteral
1891.5
161.3
151
*
Z51.5
ICD-10 Finland
Palliative care
13.3
158.6
165
154
A05AA02
ATC
ursodeoxycholic acid; oral
33.2
144.0
94
32
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
59.1
133.0
75
14
ZX112
NOMESCO Finland
Subcutaneous
53.6
127.0
73
15
A49.9
ICD-10 Finland
Bacterial infection, unspecified
6.1
111.4
246
546
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
582.2
105.3
102
*
B03XA01
ATC
erythropoietin; parenteral
39.3
105.1
65
18
L04AD01
ATC
ciclosporin; systemic
34.8
104.7
67
21
D46.2
ICD-10 Finland
Refractory anaemia with excess of blasts [RAEB]
+∞
101.3
95
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
8.5
91.2
128
175
JN4AD
NOMESCO Finland
Body CT examination
8.4
89.9
128
178
R50.9
ICD-10 Finland
Fever, unspecified
5.1
88.8
236
606
H02AB02
ATC
dexamethasone; systemic
23.9
87.9
64
29
JN4BD
NOMESCO Finland
Extensive body CT
8.7
86.7
119
158
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
460.0
84.7
83
*
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
28.9
79.7
54
20
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
45.4
78.9
47
11
ZX120
NOMESCO Finland
Intravenous
6.5
77.5
142
258
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
5.2
76.7
189
451
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
12.1
72.9
76
69
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
70.9
67
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
374.0
69.8
69
*
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
7.3
69.5
110
171
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
729.6
69.1
67
*
J01MA12
ATC
levofloxacin; systemic
4.0
67.7
261
871
C95.0
ICD-10 Finland
Acute leukaemia of unspecified cell type
+∞
65.5
62
*
J05AB11
ATC
valaciclovir; oral
4.5
65.4
193
528
WW200
NOMESCO Finland
Immunization
11.7
61.5
65
60
D46.1
ICD-10 Finland
Refractory anaemia with ring sideroblasts
332.9
61.3
61
*
J02AC03
ATC
voriconazole; systemic
326.7
60.2
60
*
D46.0
ICD-10 Finland
Refractory anaemia without ring sideroblasts, so stated
220.1
60.0
61
*
N02AA05
ATC
oxycodone; systemic
3.8
56.4
222
741
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
6.0
53.0
102
192
A03FA01
ATC
metoclopramide; systemic, rectal
4.2
52.8
169
486
A04AA02
ATC
granisetron; systemic, transdermal
542.3
52.1
51
*
A41.9
ICD-10 Finland
Sepsis, unspecified
6.0
51.4
97
179
TPX10
NOMESCO Finland
Implantation of vascular injection port
10.7
50.1
56
56
T86.0
ICD-10 Finland
Bone-marrow transplant rejection
519.5
50.0
49
*
L04AA06
ATC
mycophenolic acid; systemic
16.4
48.9
42
27
116
Kela drug reimbursment
Prostate cancer
+∞
48.4
46
*
M04AA01
ATC
allopurinol; systemic
3.4
47.7
228
853
TGC00
NOMESCO Finland
Bronchial lavation
8.6
47.5
63
79
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
47.4
45
*
L01XX05
ATC
hydroxycarbamide; oral
11.3
46.6
50
47
L03AA13
ATC
pegfilgrastim; parenteral
249.6
46.5
47
*
9983/3-C42.1
ICD-O-3
Myelodysplastic syndrome with excess blasts of bone marrow
+∞
45.2
43
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.8
42.8
440
2473
121
Kela drug reimbursment
Severe hypofunction of sexual glands
12.6
42.2
42
35
306
Kela drug reimbursment
Erythropoietin and darbepoetin
155.2
42.2
44
*
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
418.1
40.5
40
*
D64.8
ICD-10 Finland
Other specified anaemias
10.1
38.9
45
47
WW306
NOMESCO Finland
Transfer of stem cells from foreign registered donator
+∞
38.9
37
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
38.9
37
*
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
6.0
38.8
72
130
J01MA14
ATC
moxifloxacin; systemic
3.9
37.4
122
351
L02AE02
ATC
leuprorelin; implant, parenteral
136.6
37.1
39
*
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
+∞
36.8
35
*
115
Kela drug reimbursment
Breast cancer
+∞
36.8
35
*
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
11.3
36.7
39
36
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.6
35.3
347
1859
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
5.5
33.6
68
133
B73
ICPC
Leukaemia
+∞
33.6
32
*
Y84.8
ICD-10 Finland
Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
39.2
32.8
41
11
9982/3-C42.1
ICD-O-3
Myelodysplastic syndrome with ring sideroblasts and single lineage dysplasia of bone marrow
+∞
32.5
31
*
WZC00
NOMESCO Finland
Treatment plan or consultation
2.6
31.5
235
1092
C92.1
ICD-10 Finland
Chronic myeloid leukaemia [CML], BCR/ABL-positive
+∞
31.5
30
*
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
5.5
30.5
61
118
9891/3-C42.1
ICD-O-3
Acute monocytic leukemia of bone marrow
+∞
30.4
29
*
C92.5
ICD-10 Finland
Acute myelomonocytic leukaemia
+∞
30.4
29
*
WF002
NOMESCO Finland
Radical radiotherapy
111.1
29.9
32
*
WW302
NOMESCO Finland
Allogenic transfer of stem cells from relative
+∞
29.4
28
*
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
5.8
28.6
54
99
B82
ICPC
Anaemia other/unspecified
5.8
28.4
53
96
NEA10
NOMESCO Finland
Exploration of soft tissue of pelvis, percutaneous
57.3
28.4
33
6
C95.9
ICD-10 Finland
Leukaemia, unspecified
+∞
28.3
27
*
C92.4
ICD-10 Finland
Acute promyelocytic leukaemia [PML]
+∞
28.3
27
*
C91.0
ICD-10 Finland
Acute lymphoblastic leukaemia [ALL]
+∞
28.3
27
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
4.0
27.9
86
236
SPAT1088
SPAT
Blood transfusion
36.6
27.6
35
10
H02AB09
ATC
hydrocortisone; systemic
7.9
27.4
38
50
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.6
27.3
197
894
L01BB02
ATC
mercaptopurine; oral
24.9
27.2
38
16
J02AC04
ATC
posaconazole; systemic
+∞
26.2
25
*
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
+∞
26.2
25
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.3
26.1
300
1672
D70.82
ICD-10 Finland
Drug-induced neutropenia
96.7
25.8
28
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
96.7
25.8
28
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.6
25.2
90
273
WW409
NOMESCO Finland
Other aferesis
+∞
25.1
24
*
GD1AD
NOMESCO Finland
Thorax CT examination
4.5
25.1
64
152
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
5.8
24.2
45
81
V03AC03
ATC
deferasirox; oral
+∞
24.1
23
*
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
+∞
24.1
23
*
H02AB06
ATC
prednisolone; systemic
2.1
23.8
405
2613
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
8.1
23.6
32
41
HAC20
NOMESCO Finland
Total mastectomy
+∞
23.0
22
*
WD515
NOMESCO Finland
Demanding therapy of malignancy with enzyme inhibitors and similar treatments
+∞
23.0
22
*
130
Kela drug reimbursment
Malignant tumour
+∞
23.0
22
*
2050A
ICD-9 Finland
Myeloid leukaemia, Acute
+∞
22.0
21
*
C92.9
ICD-10 Finland
Myeloid leukaemia, unspecified
+∞
22.0
21
*
JN6AD
NOMESCO Finland
CT of torso and neck
27.3
21.5
29
11
HA1AA
NOMESCO Finland
X-ray mammography
6.0
21.2
38
66
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
+∞
20.9
20
*
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
+∞
20.9
20
*
D46.4
ICD-10 Finland
Refractory anaemia, unspecified
215.5
20.7
21
*
C90.0
ICD-10 Finland
Multiple myeloma
113.1
20.7
22
*
J02AC01
ATC
fluconazole; systemic
2.1
20.6
258
1461
A40.8
ICD-10 Finland
Other streptococcal sepsis
8.6
20.2
26
31
TPH04
NOMESCO Finland
Cathetrisation of vein
2.3
20.1
191
967
A41.8
ICD-10 Finland
Other specified sepsis
6.3
20.0
34
56
L02BB03
ATC
bicalutamide; oral
+∞
19.9
19
*
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
+∞
19.9
19
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
19.9
19
*
ZX090
NOMESCO Finland
Other technic of radiotherapy
75.5
19.8
22
*
EP1AE
NOMESCO Finland
Neck ultrasound examination
4.5
19.7
49
114
Y77
ICPC
Malignant neoplasm prostate
205.0
19.6
20
*
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.7
19.5
121
503
J05AB01
ATC
aciclovir; systemic
2.3
19.1
178
892
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
+∞
18.8
18
*
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
18.8
18
*
9873/3-C42.1
ICD-O-3
Acute myeloid leukemia without maturation of bone marrow
+∞
18.8
18
*
L02BG04
ATC
letrozole; oral
28.6
18.8
25
9
JN4CD
NOMESCO Finland
Very extensive body CT
7.2
18.8
28
40
B02AA02
ATC
tranexamic acid; systemic
2.8
18.0
98
380
B25.8
ICD-10 Finland
Other cytomegaloviral diseases
53.8
18.0
21
*
D72.8
ICD-10 Finland
Other specified disorders of white blood cells
23.4
17.8
25
11
1BC07, ,
NOMESCO Finland
+∞
17.8
17
*
9980/3-C42.1
ICD-O-3
Myelodysplastic syndrome with single lineage dysplasia of bone marrow
+∞
17.8
17
*
A41.1
ICD-10 Finland
Sepsis due to other specified staphylococcus
15.0
17.7
29
20
UGC12
NOMESCO Finland
Flexible bronchoscopy
3.1
17.7
79
275
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
4.4
17.6
45
107
PJA12
NOMESCO Finland
Sentinel node biopsy
184.0
17.6
18
*
D75.9
ICD-10 Finland
Disease of blood and blood-forming organs, unspecified
24.7
17.4
24
10
NK6AN
NOMESCO Finland
Total body bone isotope imaging
51.2
17.1
20
*
175
Kela drug reimbursment
Deferasirox
+∞
16.7
16
*
9985/3-C42.1
ICD-O-3
Myelodysplastic syndrome with multilineage dysplasia of bone marrow
+∞
16.7
16
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
16.7
16
*
J01MA02
ATC
ciprofloxacin; systemic
1.9
16.7
333
2191
WF049
NOMESCO Finland
Radiotherapy of metastasis
173.5
16.6
17
*
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.9
16.2
360
2444
L04AD02
ATC
tacrolimus; systemic
25.1
16.1
22
9
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.0
16.0
243
1455
L04AA01
ATC
[U] ciclosporin
14.9
15.9
26
18
B25.9
ICD-10 Finland
Cytomegaloviral disease, unspecified
61.3
15.8
18
*
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
34.1
15.8
20
6
1DB06, ,
NOMESCO Finland
+∞
15.7
15
*
9920/3-C42.1
ICD-O-3
Therapy-related myeloid neoplasm of bone marrow
+∞
15.7
15
*
KE1AT
NOMESCO Finland
Biopsy of prostata with ultrasoudnguidance
5.0
15.6
34
71
A02BC02
ATC
pantoprazole; systemic
1.9
15.2
500
3807
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
2.6
15.1
92
378
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
6.7
15.0
24
37
8090/3-C44.5
ICD-O-3
Basal cell carcinoma, NOS, of skin of trunk
+∞
14.6
14
*
XW4XT
NOMESCO Finland
Biopsy of other inner organ with radiological guidance guidance
+∞
14.6
14
*
C93.0
ICD-10 Finland
Acute monoblastic/monocytic leukaemia
+∞
14.6
14
*
ZX121
NOMESCO Finland
Central venous catheter
81.7
14.6
16
*
D46.3
ICD-10 Finland
Refractory anemia with excess of blasts with transformation
81.7
14.6
16
*
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.5
14.4
102
450
JN3AD
NOMESCO Finland
Abdominal CT examination
2.6
14.3
85
345
YL1BD
NOMESCO Finland
Extensive CT examination of pelvis for dose design of radiotherapy
+∞
13.6
13
*
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
13.6
13
*
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
13.6
13
*
C50.99
ICD-10 Finland
Breast, unspecified
+∞
13.6
13
*
TNE20
NOMESCO Finland
Bone marrow aspiration, pelvis
40.8
13.2
16
*
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.9
13.1
217
1325
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
28.9
13.0
17
6
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
3.0
12.9
58
202
TPH00
NOMESCO Finland
Phlebotomy
14.3
12.8
21
15
UJF32
NOMESCO Finland
Coloscopy
1.9
12.8
195
1157
A04AA55
ATC
palonosetron, combinations; systemic
+∞
12.5
12
*
WW304
NOMESCO Finland
Transfer of stem cells from registered domestic donator
+∞
12.5
12
*
128
Kela drug reimbursment
Cancers of female genital organs
+∞
12.5
12
*
D46
ICD-10 Finland
Myelodysplastic syndromes
+∞
12.5
12
*
9867/3-C42.1
ICD-O-3
Acute myelomonocytic leukemia, NOS, of bone marrow
+∞
12.5
12
*
9866/3-C42.1
ICD-O-3
Acute promyelocytic leukemia, t(15;17)(q22;q11-12) of bone marrow
+∞
12.5
12
*
9895/3-C42.1
ICD-O-3
Acute myeloid leukemia with myelodysplasia-related changes of bone marrow
+∞
12.5
12
*
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
132.0
12.5
13
*
C44.41
ICD-10 Finland
Basocellular carcinoma of the skin of the scalp and neck
132.0
12.5
13
*
ZX070
NOMESCO Finland
Intensity modified radiotherapy
132.0
12.5
13
*
L02BA01
ATC
tamoxifen; oral
132.0
12.5
13
*
B99
ICD-10 Finland
Other and unspecified infectious diseases
4.7
12.4
29
64
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
3.5
12.4
43
128
212
Kela drug reimbursment
Gout
3.8
12.1
37
101
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
9.5
12.0
24
26
D47.1
ICD-10 Finland
Chronic myeloproliferative disease
21.7
12.0
17
8
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.6
11.9
69
276
D61.9
ICD-10 Finland
Aplastic anaemia, unspecified
30.5
11.7
15
5
XX3DW
NOMESCO Finland
Time consuming IT work
3.3
11.7
44
138
R04.0
ICD-10 Finland
Epistaxis
2.4
11.6
84
373
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
66.0
11.6
13
*
D53.1
ICD-10 Finland
Other megaloblastic anaemias, not elsewhere classified
23.3
11.6
16
7
9945/3-C42.1
ICD-O-3
Chronic myelomonocytic leukemia, NOS, of bone marrow
+∞
11.5
11
*
2AX04, ,
NOMESCO Finland
+∞
11.5
11
*
9874/3-C42.1
ICD-O-3
Acute myeloid leukemia with maturation of bone marrow
+∞
11.5
11
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
11.5
11
*
C93.1
ICD-10 Finland
Chronic myelomonocytic leukaemia
+∞
11.5
11
*
WD505
NOMESCO Finland
Simple enzyme inhibitor or similar therapy of methastized malignancy
+∞
11.5
11
*
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
121.7
11.5
12
*
L57.0
ICD-10 Finland
Actinic keratosis
2.5
11.4
78
338
ZXD05
NOMESCO Finland
Urgent procedure
1.8
11.3
236
1534
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
25.4
11.2
15
6
J01FF01
ATC
clindamycin; systemic
1.8
11.0
197
1222
TAB00
NOMESCO Finland
Lumbar puncture
3.4
10.9
40
123
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
44.0
10.9
13
*
H02AB07
ATC
prednisone; oral
2.0
10.8
124
665
Z3231
NOMESCO Finland
Registered nurse
1.8
10.7
200
1257
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
4.2
10.7
28
68
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
60.8
10.6
12
*
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.7
10.6
263
1790
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
3.9
10.6
31
82
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.4
10.5
73
318
399
Kela drug reimbursment
Venetoclax
111.5
10.4
11
*
L01XX52
ATC
venetoclax; oral
111.5
10.4
11
*
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
+∞
10.4
10
*
C67.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of bladder
+∞
10.4
10
*
D89.89
ICD-10 Finland
Other specified disorders involving the immune mechanism, not elsewhere classified
+∞
10.4
10
*
C92.3
ICD-10 Finland
Myeloid sarcoma
+∞
10.4
10
*
J02AC05
ATC
isavuconazole; systemic
+∞
10.4
10
*
J05AX18
ATC
letermovir; oral
+∞
10.4
10
*
1DB07, ,
NOMESCO Finland
+∞
10.4
10
*
A07AA02
ATC
nystatin; oral
2.7
10.4
56
216
XG410
NOMESCO Finland
Flow-volume spirometry
3.2
10.3
42
138
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
3.5
10.3
35
103
KCD02
NOMESCO Finland
Transurethral resection of bladder
12.4
9.9
17
14
D72.9
ICD-10 Finland
Disorder of white blood cells, unspecified
26.4
9.8
13
5
A79
ICPC
Malignancy NOS
55.7
9.7
11
*
M87.1
ICD-10 Finland
Osteonecrosis due to drugs
55.7
9.7
11
*
B74
ICPC
Malignant neoplasm blood other
101.2
9.4
10
*
1518, ,
Kela drug reimbursment
101.2
9.4
10
*
L01BC06
ATC
capecitabine; oral
+∞
9.4
9
*
C50.11
ICD-10 Finland
Malignant tumor of the central part of the mammary gland,ductal tumor
+∞
9.4
9
*
C83.3
ICD-10 Finland
Diffuse large B-cell lymphoma
+∞
9.4
9
*
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
+∞
9.4
9
*
Z85.6
ICD-10 Finland
Personal history of leukaemia
+∞
9.4
9
*
C85.9
ICD-10 Finland
Non-Hodgkin lymphoma, unspecified
+∞
9.4
9
*
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
+∞
9.4
9
*
D11AH01
ATC
tacrolimus; topical
12.5
9.4
16
13
H02AB04
ATC
methylprednisolone; systemic
2.0
9.4
119
659
GA4AT
NOMESCO Finland
Cathetrisation of pleural cavity with ultrasound guidance
10.8
9.3
17
16
C03CA01
ATC
furosemide; systemic
1.6
9.3
339
2526
R4110
NOMESCO Finland
Physiotherapy
1.7
9.1
187
1200
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
3.1
9.1
38
127
B01AB10
ATC
tinzaparin; parenteral
2.5
9.1
58
243
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.5
8.9
58
246
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
3.5
8.8
30
88
N02AX02
ATC
tramadol; systemic, rectal
1.6
8.7
305
2240
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
3.0
8.7
38
131
B01AB05
ATC
enoxaparin; parenteral
1.7
8.6
215
1454
N05CF01
ATC
zopiclone; oral
1.6
8.5
262
1863
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
20.3
8.5
12
6
KE3AT
NOMESCO Finland
Transrectal gold marker implantation in prostate under ultrasound guidance
91.0
8.4
9
*
C44.61
ICD-10 Finland
Basocellular carcinoma of the skin of the upper extremity including the shoulder
91.0
8.4
9
*
A04AD12
ATC
aprepitant; systemic
+∞
8.3
8
*
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
+∞
8.3
8
*
C67.9
ICD-10 Finland
Malignant neoplasm: Bladder, unspecified
+∞
8.3
8
*
E89.4
ICD-10 Finland
Postprocedural ovarian failure
+∞
8.3
8
*
C20.91
ICD-10 Finland
Malignant tumor of the rectum invasive carcinoma
+∞
8.3
8
*
PJ5AN
NOMESCO Finland
Localisation of sentinell lymphnode with isotope imaging
+∞
8.3
8
*
L02BB04
ATC
enzalutamide; oral
+∞
8.3
8
*
L03AA14
ATC
lipegfilgrastim; parenteral
+∞
8.3
8
*
Z51.3
ICD-10 Finland
Blood transfusion (without reported diagnosis)
+∞
8.3
8
*
C50.90
ICD-10 Finland
Malignant tumor in other or unspecified location in mammary gland without histology
+∞
8.3
8
*
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
8.3
162
1024
PJ2AT
NOMESCO Finland
Biopsy of lymphnode with ultrasound guidance
33.7
8.1
10
*
EB1CI
NOMESCO Finland
Cone beam imaging of teeth and jaws (3-4 quarters)
10.2
8.1
15
15
ED1AA
NOMESCO Finland
Mandibular X-ray examination
22.3
8.0
11
5
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
3.9
8.0
23
60
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.7
8.0
183
1206
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
2.8
7.9
40
150
L03.9
ICD-10 Finland
Cellulitis, unspecified
4.1
7.8
21
52
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
3.6
7.7
25
71
122
Kela drug reimbursment
Aplastic anaemia
45.4
7.7
9
*
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.4
7.7
52
224
D69.3
ICD-10 Finland
Idiopathic thrombocytopenic purpura
8.1
7.6
16
20
A02BC01
ATC
omeprazole; systemic
1.6
7.6
216
1501
SAA03
NOMESCO Finland
Extended examination of mouth
1.6
7.6
228
1605
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
2.7
7.6
40
153
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
3.1
7.5
31
103
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
2.9
7.5
34
120
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
80.8
7.4
8
*
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
80.8
7.4
8
*
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
7.8
7.4
16
21
ZXC96
NOMESCO Finland
Robot assisted procedure
11.0
7.3
13
12
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
9.5
7.3
14
15
20500
ICD-8 Finland
Myeloid leukaemia, Acute
+∞
7.3
7
*
D61.0
ICD-10 Finland
Constitutional aplastic anaemia
+∞
7.3
7
*
8120/3-C67.9
ICD-O-3
Transitional cell carcinoma, NOS, of bladder, NOS
+∞
7.3
7
*
B44.0
ICD-10 Finland
Invasive pulmonary aspergillosis
+∞
7.3
7
*
C50.40
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, no histological veryfication
+∞
7.3
7
*
YX9BD
NOMESCO Finland
Other extensive CT eamination for dose design of radiotherapy
+∞
7.3
7
*
C54.11
ICD-10 Finland
Adenocarcinoma of the endometrium
+∞
7.3
7
*
8140/3-C20.9
ICD-O-3
Adenocarcinoma, NOS, of rectum, NOS
+∞
7.3
7
*
T86.9
ICD-10 Finland
Failure and rejection of unspecified transplanted organ and tissue
+∞
7.3
7
*
YG1AD
NOMESCO Finland
CT examination of thorax for dose design of radiotherapy
+∞
7.3
7
*
163
Kela drug reimbursment
Abiraterone and enzalutamide
+∞
7.3
7
*
X76
ICPC
Malignant neoplasm breast female
+∞
7.3
7
*
C50.42
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, lobular tumor
+∞
7.3
7
*
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.7
7.3
160
1042
PJA10
NOMESCO Finland
Exploration of lymph nodes
15.9
7.2
11
7
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
2.5
7.2
45
187
ZXE00
NOMESCO Finland
One hour or less
1.5
7.2
253
1844
D47.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
30.3
7.2
9
*
J01DB01
ATC
cefalexin; oral
1.6
7.1
552
4747
N05BA06
ATC
lorazepam; systemic, sublingual
2.3
7.1
52
233
A46
ICD-10 Finland
Erysipelas
1.7
7.1
129
798
R79.8
ICD-10 Finland
Other specified abnormal findings of blood chemistry
10.1
7.0
13
13
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
5.5
6.9
19
35
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
5.9
6.9
18
31
5BA08, ,
NOMESCO Finland
13.9
6.9
11
8
HAB40
NOMESCO Finland
Wedge excision of mammary gland
13.9
6.9
11
8
B99
ICPC
Blood/lymph/spleen disease other
13.9
6.9
11
8
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
3.8
6.8
20
53
WX302
NOMESCO Finland
Thoracal epidural anesthesy
3.8
6.8
20
53
JN6DR
NOMESCO Finland
PET-CT of whole body metabolism
11.1
6.8
12
11
D64.1
ICD-10 Finland
Secondary sideroblastic anaemia due to disease
40.4
6.8
8
*
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
2.1
6.8
61
298
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
16.9
6.8
10
6
HA1AT
NOMESCO Finland
Biopsy of mammary glands with ultrasound guidance
16.9
6.8
10
6
D07AB08
ATC
desonide; topical
2.0
6.7
79
426
9961/3-C42.1
ICD-O-3
Primary myelofibrosis of bone marrow
22.7
6.7
9
*
WX110
NOMESCO Finland
Infiltration anesthesia
1.5
6.7
414
3380
GCA98
NOMESCO Finland
Other bronchoscopic procedure on bronchus
10.1
6.5
12
12
8130/2-C67.9
ICD-O-3
Papillary urothelial carcinoma, non-invasive of bladder, NOS
70.4
6.4
7
*
YL1AD
NOMESCO Finland
CT examination of pelvis for dose design of radiotherapy
70.4
6.4
7
*
308
Kela drug reimbursment
Alprostadil, sildenafil and combination product containing aviptadil and phentolamine
70.4
6.4
7
*
L03AB05
ATC
interferon alfa-2b; parenteral
70.4
6.4
7
*
XW000, ,
SPAT
70.4
6.4
7
*
E83.1
ICD-10 Finland
Disorders of iron metabolism
14.4
6.4
10
7
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
2.7
6.4
33
125
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
2.7
6.4
33
125
WVA20
NOMESCO Finland
Medicine administration
3.5
6.3
21
61
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
2.7
6.3
33
126
WB121
NOMESCO Finland
Demanding neoadjuvant cytostatic therapy
+∞
6.3
6
*
C92.2
ICD-10 Finland
Atypical chronic myeloid leukaemia, BCR/ABL- negative
+∞
6.3
6
*
C83.9
ICD-10 Finland
Non-follicular (diffuse) lymphoma, unspecified
+∞
6.3
6
*
ZX080
NOMESCO Finland
Image guided radiotherapy
+∞
6.3
6
*
8140/3-C18.7
ICD-O-3
Adenocarcinoma, NOS, of sigmoid colon
+∞
6.3
6
*
C92.7
ICD-10 Finland
Other myeloid leukaemia
+∞
6.3
6
*
WB203
NOMESCO Finland
Simple adjuvant hormone therapy of malignancy
+∞
6.3
6
*
HA003
NOMESCO Finland
Radiotherapy after partial ablation of mammary gland
+∞
6.3
6
*
HA013
NOMESCO Finland
Radiotherapy after total ablation of mammary gland
+∞
6.3
6
*
9986/3-C42.1
ICD-O-3
Myelodysplastic syndrome with isolated del (5q) of bone marrow
+∞
6.3
6
*
WB123
NOMESCO Finland
Demanding adjuvant cytostatic therapy
+∞
6.3
6
*
L03AA10
ATC
lenograstim; parenteral
+∞
6.3
6
*
KEC01
NOMESCO Finland
Percutaneous endoscopic radical prostatectomy
+∞
6.3
6
*
C34.1
ICD-10 Finland
Malignant neoplasm: Upper lobe, bronchus or lung
+∞
6.3
6
*
C50.81
ICD-10 Finland
Overall malignant tumor of the mammary gland, ductal tumor
+∞
6.3
6
*
ZX013
NOMESCO Finland
Radiotherapy with large shaped fields - SSD therapy
+∞
6.3
6
*
L02BG03
ATC
anastrozole; oral
+∞
6.3
6
*
G03DC03
ATC
lynestrenol; oral
7.1
6.2
14
20
G03HA01
ATC
cyproterone; systemic
26.9
6.2
8
*
TPX15
NOMESCO Finland
Removal of vascular injection port
26.9
6.2
8
*
THW99
NOMESCO Finland
Other minor procedure in surgery of mammary gland
26.9
6.2
8
*
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.7
6.2
123
777
JA1AE
NOMESCO Finland
Ultrasound examination of groin and abdominal wall
4.0
6.2
17
43

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
293
65
71.43
307.65
4.8
1.3
—
—
—
0
0
299
34
141.65
307.65
1.4
1.1
—
—
—
0
0
181
28
83.78
307.65
1.7
1.0
—
—
—
0
0
378
523
13.04
286.22
7.3
2.1
65.53
66.40
e9/l
0.06
308
424
432
727
12.02
280.28
7.7
2.0
1.89
1.72
%
1.40
404
626
219
138
21.64
267.41
2.2
1.6
—
—
—
0
0
148
27
67.36
267.02
1.4
1.2
—
—
—
0
0
148
29
62.70
263.36
2.9
2.4
—
—
—
0
0
293
360
12.41
238.26
12.3
3.6
1.58
0.73
%
3.82
259
97
160
62
32.18
237.42
1.5
1.5
111.11
102.50
u/ml
—
44
8
180
97
23.80
235.01
1.3
1.2
152.41
20.82
u/l
7.45
156
87
254
271
13.39
227.27
2.0
1.6
1.27
1.52
g/l
2.80
219
231
144
52
33.71
218.28
10.4
2.4
1.36
1.49
%
0.07
128
43
179
115
19.88
214.73
3.7
2.7
3.66
3.60
g/l
0.11
174
106
152
70
26.70
211.09
1.4
1.4
—
—
—
0
0
167
106
19.75
201.10
1.4
1.3
—
—
—
0
0
144
74
23.62
190.73
1.4
1.3
250.54
223.95
u/ml
0.29
91
37
236
306
10.61
180.97
3.0
1.8
10.41
11.31
g/l
1.74
224
275
239
329
10.02
174.48
12.8
3.6
0.90
0.65
%
0.60
208
87
238
340
9.62
168.23
12.8
3.7
0.22
0.04
%
3.19
206
77
108
37
33.70
165.50
12.1
2.9
—
—
—
0
0
193
219
11.37
162.54
1.5
1.3
—
—
—
0
0
147
111
16.07
160.48
1.8
1.3
—
—
—
0
0
265
471
7.99
153.92
2.3
1.5
65.91
66.75
g/l
0.87
252
414
198
250
10.26
153.58
1.6
1.2
1.17
1.10
g/l
0.34
188
225
103
39
30.26
152.53
10.7
2.1
44.00
57.03
%
2.78
87
31
222
328
9.05
151.61
13.0
3.8
5.23
0.02
%
5.04
188
66
117
65
20.99
148.86
1.3
1.0
—
—
—
0
0
224
389
7.67
131.38
1.6
1.4
—
—
—
0
0
228
436
6.97
121.24
1.6
1.4
—
—
—
0
0
295
737
5.82
117.96
12.3
4.5
1.09
1.02
mmol/l
3.43
284
658
98
68
16.33
111.06
1.3
1.0
—
—
—
0
0
118
112
12.23
110.96
3.8
2.8
92.05
86.57
%
1.32
118
106
291
782
5.33
105.58
10.6
2.5
0.81
0.82
mmol/l
1.79
276
711
237
536
5.91
104.62
1.6
1.7
—
—
—
0
0
205
413
6.37
102.19
1.8
1.4
—
—
—
0
0
85
53
17.87
101.61
1.2
1.2
—
—
—
0
0
521
2304
4.77
97.65
31.5
5.1
—
—
—
0
0
394
1447
4.47
94.24
8.2
2.5
1477.27
9653.27
umol/l
4.16
375
1213
92
7
148.64
88.10
1.0
1.0
—
—
—
0
0
91
7
146.81
87.04
1.5
1.1
—
—
—
0
0
415
1655
4.21
86.98
15.7
3.9
—
—
—
0
0
502
2289
4.32
86.90
23.5
5.0
0.65
0.65
%
0.05
484
2099
512
2377
4.33
86.15
27.1
5.2
10.70
8.75
%
5.84
492
2186
508
2369
4.26
84.35
24.8
4.9
1.84
2.96
%
16.27
489
2179
514
2421
4.27
84.02
25.8
5.1
32.45
25.96
%
16.51
493
2235
87
9
108.60
80.78
4.4
1.1
—
—
—
0
0
386
1536
3.98
79.55
19.0
2.1
—
—
—
0
0
279
889
4.32
78.65
4.4
1.9
29.24
30.30
s
1.70
269
854
114
175
7.45
72.93
1.8
1.3
49.90
50.59
mg/l
0.03
102
143
112
170
7.52
72.37
1.8
1.3
5.33
1.25
ratio
—
7
16
491
2404
3.80
72.00
22.9
5.0
47.87
58.83
%
35.80
468
2223
76
8
105.08
70.29
4.9
1.0
—
—
—
0
0
111
176
7.18
68.82
1.8
1.3
54.34
37.19
mg/l
0.31
98
145
237
746
4.12
66.66
2.3
2.4
39.21
22.77
%
15.97
194
630
126
236
6.17
66.29
2.5
1.7
4.52
2.20
ug/l
0.46
113
198
309
1171
3.71
66.21
17.6
2.0
—
—
—
0
0
74
76
10.65
65.22
5.2
2.0
—
—
—
0
0
464
2298
3.50
64.51
17.9
2.3
—
—
—
0
0
262
903
3.86
64.47
2.3
2.3
18.31
12.74
umol/l
13.44
253
820
244
804
3.96
64.05
2.2
2.3
1.94
2.27
g/l
17.40
235
733
182
499
4.45
61.24
8.3
5.3
9.12
11.28
mmol/l
2.78
174
465
495
2625
3.41
60.03
24.9
5.0
0.11
0.21
e9/l
27.67
441
2275
517
2835
3.42
58.86
46.8
5.6
3.40
4.47
e9/l
2.15
483
2447
492
2633
3.34
58.07
25.6
3.6
13.50
12.54
umol/l
0.92
480
2450
83
117
7.82
56.94
1.5
1.8
28.29
11.68
mg/l
1.32
66
108
476
2534
3.24
55.98
20.9
4.8
0.68
0.62
e9/l
0.32
432
2161
476
2543
3.22
55.46
20.9
4.8
0.03
0.04
e9/l
6.10
431
2179
480
2585
3.21
54.99
21.6
4.9
1.64
1.79
e9/l
0.64
440
2257
276
1086
3.38
54.01
2.9
1.7
3.29
1.26
mg/l
3.63
246
837
114
238
5.44
52.98
1.6
1.3
3.66
3.75
g/l
0.28
105
209
114
238
5.44
52.98
1.6
1.3
6.44
7.70
g/l
9.95
105
209
234
848
3.51
52.00
1.6
1.2
2.49
2.76
g/l
1.21
198
473
83
131
6.97
51.33
1.8
1.3
—
—
—
0
0
105
220
5.36
48.47
1.6
1.3
11.44
10.85
g/l
0.44
96
191
213
774
3.41
46.58
2.1
1.9
—
—
—
0
0
51
6
90.87
46.44
1.4
1.0
—
—
—
0
0
50
5
106.70
46.35
1.2
1.0
—
—
—
0
0
417
2220
2.88
46.13
4.9
2.6
692.40
131.47
ug/l
12.32
389
2005
37
21
18.44
45.73
2.0
1.4
36.63
46.48
%
1.03
19
13
484
2813
2.89
44.86
17.9
5.3
1.20
1.21
mmol/l
2.78
415
2393
169
545
3.68
44.31
14.2
2.3
8.85
9.02
umol/l
0.03
164
460
331
1590
2.87
44.01
2.6
2.2
2.87
2.98
mg/l
0.37
283
1327
451
2544
2.82
43.97
15.0
5.0
1.20
1.21
mmol/l
4.04
418
2245
421
2372
2.68
39.86
14.6
3.6
32.51
34.98
g/l
12.29
398
2165
65
111
6.30
37.06
1.2
1.2
—
—
—
0
0
85
187
4.98
36.85
1.7
1.3
36.98
36.74
g/l
0.11
76
158
37
34
11.37
34.88
1.3
1.1
—
—
—
0
0
251
1194
2.62
32.19
2.3
1.3
—
—
—
0
0
306
1620
2.46
31.05
13.8
2.9
7.42
7.40
ph
3.15
55
265
279
1429
2.48
30.30
2.1
1.8
1288.80
1141.75
nmol/l
1.50
226
1069
245
1242
2.42
26.66
11.9
3.4
79.37
81.98
%
0.87
239
1205
115
407
3.14
25.21
1.9
1.9
0.20
0.20
g/l
0.13
101
365
24
0
+∞
25.13
1.8
0.0
19.50
—
%
—
24
0
29
6
50.07
24.43
4.1
1.3
—
—
—
0
0
279
1555
2.23
23.85
5.5
2.5
35.61
34.82
u/l
0.07
263
1476
147
633
2.63
22.26
2.0
1.7
—
—
—
0
0
138
577
2.69
22.16
3.7
1.4
—
—
—
0
0
270
1549
2.13
20.94
2.1
1.6
18.78
19.89
nmol/l
0.64
254
1306
227
1219
2.21
20.81
34.1
4.3
—
—
—
0
0
391
2607
2.00
19.77
2.8
2.1
89.99
91.79
pmol/l
0.32
278
1341
30
18
17.27
19.29
1.2
1.2
—
—
—
0
0
467
3346
1.98
18.82
12.4
4.3
6.97
6.90
mmol/l
0.29
453
3123
415
2897
1.92
17.62
14.5
20.4
1.32
1.42
inr
1.05
108
816
80
288
2.98
16.85
2.8
1.3
3.28
2.66
ug/l
0.53
64
212
125
565
2.44
16.83
10.9
3.7
—
—
—
0
0
21
7
30.77
16.17
1.1
1.0
—
—
—
0
0
245
1471
1.97
16.00
2.5
1.6
—
—
—
0
0
15
0
+∞
15.67
1.1
0.0
—
—
—
0
0
22
10
22.59
15.60
2.0
1.0
—
—
—
0
0
35
75
4.84
15.54
1.1
1.3
81.93
287.07
miu/ml
—
5
24
94
386
2.63
15.43
6.5
3.9
5.20
5.22
kpa
0.04
85
366
93
380
2.64
15.42
6.4
4.0
7.42
7.39
ph
0.88
12
38
68
235
3.07
15.36
7.8
4.2
25.56
24.91
mmol/l
1.00
61
213
34
75
4.69
14.59
9.7
3.0
49.18
60.40
%
2.80
34
75
524
4081
1.86
14.48
31.3
5.0
83.85
78.39
u/l
2.22
508
3716
23
15
15.75
14.47
1.3
1.1
—
—
—
0
0
23
16
14.77
14.12
1.1
1.1
—
—
—
0
0
33
73
4.68
14.11
1.1
1.1
—
—
—
0
0
66
236
2.96
14.05
1.5
1.5
—
—
—
0
0
163
884
2.07
13.94
4.5
2.8
2.33
2.47
e6/l
0.07
86
493
21
13
16.55
13.51
1.1
1.1
—
—
—
0
0
29
60
4.98
13.41
2.4
2.6
—
—
—
0
0
123
618
2.17
12.77
1.4
1.3
570.32
541.82
titre
0.07
31
143
261
1702
1.80
12.64
3.4
2.1
48.74
60.92
u/l
3.07
235
1549
78
323
2.57
12.55
5.2
2.8
5.39
5.34
e9/l
0.01
57
237
272
1799
1.78
12.54
4.6
2.1
2.30
2.35
mmol/l
5.90
239
1477
22
38
5.93
12.32
1.1
1.1
—
—
—
0
0
262
1725
1.78
12.20
4.9
3.0
243.75
97.37
e6/l
0.57
210
1340
279
1871
1.76
12.19
4.7
3.3
—
—
—
0
0
25
51
5.03
11.75
3.0
1.9
2.56
7804.18
u/l
—
5
12
473
3691
1.71
11.74
6.8
4.6
206.00
2493.62
e6/l
1.55
11
74
17
9
19.27
11.62
1.3
1.4
—
—
—
0
0
70
286
2.59
11.57
7.4
4.0
—
—
—
0
0
161
932
1.92
11.24
4.4
2.7
1.23
1.19
e6/l
0.04
86
539
236
1541
1.76
11.13
5.0
2.9
0.47
0.46
e6/l
0.04
185
1186
228
1488
1.75
10.71
5.0
2.9
—
—
—
0
0
34
97
3.62
10.42
2.5
1.1
—
—
—
0
0
20
38
5.37
10.15
2.4
1.1
—
—
—
0
0
281
1965
1.67
10.14
5.9
3.5
64.70
126.62
e6/l
1.30
219
1427
115
613
2.03
10.13
4.2
3.3
1.54
2.10
mmol/l
0.69
97
506
316
2291
1.64
9.82
40.0
7.9
0.19
0.00
e9/l
0.63
266
1864
60
247
2.55
9.77
1.4
1.3
—
—
—
0
0
292
2078
1.65
9.76
3.9
3.1
2155.70
1905.26
ng/l
0.42
274
1793
126
708
1.93
9.52
7.0
6.0
4.90
5.08
kpa
1.22
121
671
126
708
1.93
9.52
7.0
6.0
11.24
11.25
kpa
0.01
120
670
73
334
2.31
9.45
1.7
1.1
—
—
—
0
0
115
631
1.96
9.31
8.0
6.2
94.15
94.83
%
0.34
109
603
36
116
3.20
9.17
2.4
1.3
30.57
1185.55
e6/l
0.75
30
104
125
712
1.90
9.04
7.7
6.0
1.32
1.38
mmol/l
0.05
100
553
191
1251
1.70
8.61
4.5
4.2
76.48
385.17
ng/l
4.15
165
1067
23
57
4.13
8.57
1.4
1.4
—
—
—
0
0
35
116
3.11
8.53
2.5
1.2
11.03
67.68
e6/l
0.64
29
101
20
47
4.34
7.97
1.7
1.4
—
—
—
0
0
22
58
3.87
7.57
1.5
1.4
110677.50
40160.22
e6/l
0.36
12
36
84
445
1.99
7.49
2.3
2.0
33.81
30.53
u/l
0.41
69
356
88
475
1.96
7.44
9.5
6.7
—
—
—
0
0
83
447
1.96
7.06
5.0
4.3
—
—
—
0
0
23
67
3.51
6.88
1.5
1.4
1570.29
1722.71
e6/l
0.08
17
49
480
4024
1.50
6.83
6.0
4.0
25.64
13.32
mm/h
20.84
444
3639
178
1209
1.61
6.80
3.6
2.4
5.42
4.87
e6/l
0.45
166
1080
37
150
2.54
6.28
1.5
1.5
1.14
1.12
g/l
0.07
37
143
16
39
4.17
6.11
1.0
1.2
—
—
—
0
0
36
146
2.54
6.11
1.5
1.4
0.25
0.22
g/l
0.95
36
141
19
53
3.65
6.07
1.2
1.1
—
—
—
0
0
11
11
10.12
6.04
9.3
1.5
—
—
—
0
0
467
5349
0.69
6.02
4.6
5.3
2.32
2.57
mmol/l
6.71
415
4837
29
107
2.78
5.91
5.9
3.4
—
—
—
0
0
452
3805
1.44
5.88
6.8
4.2
—
—
—
0
0
59
303
2.02
5.76
9.6
8.5
—
—
—
0
0
168
1177
1.54
5.52
4.2
2.7
523.54
546.35
mosm/kgh2o
0.92
151
984
17
47
3.68
5.50
2.8
1.2
—
—
—
0
0
14
25
5.68
5.39
7.6
2.5
—
—
—
0
0
14
25
5.68
5.39
1.4
1.2
—
—
—
0
0
21
69
3.10
5.25
2.8
1.2
10.93
24.44
iu/l
1.84
14
62
14
26
5.46
5.24
1.2
1.2
14.39
12.94
ug/l
0.31
14
26
16
44
3.69
5.22
7.1
2.9
—
—
—
0
0
17
49
3.52
5.19
1.2
1.2
—
—
—
0
0
36
160
2.31
5.05
5.0
3.5
—
—
—
0
0
445
5076
0.71
4.98
5.8
6.4
40.20
41.12
mmol/mol
1.19
405
4625
33
143
2.37
4.91
1.9
1.5
11012.42
15268.34
e6/l
0.44
26
99
374
3106
1.39
4.89
4.0
2.9
73.79
48.56
u/l
4.06
341
2817
22
78
2.87
4.85
3.0
1.3
15.80
7.83
u/l
0.69
17
68
278
2202
1.41
4.78
2.5
2.2
76.20
77.70
nmol/l
0.39
246
1887
59
326
1.88
4.69
2.4
2.5
0.75
0.34
e6/l
0.46
59
315
17
53
3.26
4.63
1.5
1.5
—
—
—
0
0
33
147
2.30
4.63
7.4
3.6
7.44
7.42
ph
1.13
28
127
11
18
6.18
4.61
1.0
1.1
—
—
—
0
0
72
427
1.76
4.56
6.2
2.6
1.20
1.22
mmol/l
1.53
67
351
28
117
2.44
4.52
2.1
2.5
34.95
36.56
umol/l
0.13
21
107
27
111
2.48
4.51
1.5
1.5
—
—
—
0
0
456
5144
0.73
4.45
4.2
4.6
1.27
1.43
mmol/l
10.91
401
4637
28
118
2.42
4.44
7.8
3.7
2.51
2.54
mmol/l
0.02
23
77
25
100
2.55
4.42
2.2
2.6
—
—
—
0
0
102
671
1.60
4.37
1.3
1.2
—
—
—
0
0
105
1523
0.64
4.33
3.3
3.2
—
—
—
0
0
10
16
6.32
4.30
1.2
1.4
—
—
—
0
0
304
2478
1.37
4.30
4.9
4.1
33.11
61.86
ng/l
1.41
245
1860
34
159
2.19
4.27
1.3
1.2
—
—
—
0
0
101
667
1.59
4.26
3.2
3.2
274.58
278.79
ng/l
0.04
90
617
14
35
4.05
4.11
1.1
1.9
16.31
15.01
umol/l
0.17
14
30
12
26
4.67
4.07
1.5
1.3
—
—
—
0
0
188
1433
1.41
3.93
1.7
1.7
81579449.27
8562071.49
pmol/l
0.43
152
1168
11
23
4.83
3.88
1.5
1.0
—
—
—
0
0
11
23
4.83
3.88
1.1
1.0
—
—
—
0
0
18
65
2.81
3.87
1.4
1.6
0.58
0.87
g/l
0.51
13
53
97
1395
0.65
3.80
2.5
1.6
1.63
1.31
mmol/l
2.51
92
1152
14
44
3.22
3.79
1.4
1.2
—
—
—
0
0
44
238
1.90
3.77
3.2
3.1
4.20
4.41
pmol/l
0.64
39
206
469
5207
0.75
3.63
4.5
4.7
4.01
4.42
mmol/l
11.41
417
4731
10
21
4.81
3.56
1.2
1.0
—
—
—
0
0
23
99
2.36
3.53
2.4
1.7
10.35
15.89
u/ml
1.13
23
76
24
107
2.28
3.41
3.1
2.2
13.56
16.06
%
1.93
15
52
78
518
1.56
3.24
4.0
2.9
4.53
4.49
kpa
0.05
73
494
24
110
2.22
3.22
2.5
2.9
—
—
—
0
0
35
187
1.91
3.15
2.2
1.8
—
—
—
0
0
13
44
2.99
3.14
1.5
1.2
0.50
0.37
g/l
—
7
35
15
57
2.66
2.98
1.2
1.2
3.89
8.91
u/ml
—
9
23
27
500
0.52
2.85
1.6
1.6
—
—
—
0
0
44
262
1.72
2.82
6.0
4.5
—
—
—
0
0
77
529
1.51
2.77
4.2
3.2
—
—
—
0
0
32
175
1.86
2.72
2.3
3.5
0.85
0.84
nmol/l
0.05
21
137
20
92
2.20
2.69
1.5
1.5
—
—
—
0
0
163
1291
1.33
2.62
4.7
3.7
—
—
—
0
0
6
181
0.33
2.56
2.5
1.4
—
—
—
0
0
308
2666
1.26
2.47
4.7
3.8
0.00
0.01
estimate
0.69
62
476
6
12
5.03
2.40
3.5
2.0
—
—
—
0
0
252
2139
1.26
2.37
4.5
3.6
5.78
5.98
ph
—
9
98
10
33
3.06
2.36
1.6
1.3
—
—
—
0
0
210
1747
1.28
2.33
5.8
4.1
—
—
—
0
0
14
59
2.40
2.30
1.1
1.2
—
—
—
0
0
26
142
1.86
2.25
1.2
1.2
—
602.00
—
0
5
490
5281
0.81
2.19
6.0
4.9
6.11
6.11
mmol/l
0.00
433
4700
307
2689
1.23
2.14
4.7
3.8
0.00
0.00
estimate
-0.00
50
433
48
316
1.55
2.14
3.3
2.5
—
—
—
0
0
26
145
1.82
2.13
1.5
1.2
—
—
—
0
0
458
4964
0.81
2.12
5.0
4.2
1.36
1.26
mmol/l
2.09
409
4428
5
10
5.02
2.07
2.0
2.0
—
—
—
0
0
8
26
3.10
2.01
1.0
1.2
105.50
137.31
nmol/l
—
8
26
101
1292
0.75
1.98
2.8
2.8
0.79
0.78
ug/l
0.05
61
894
301
2651
1.22
1.95
6.6
5.2
0.00
0.00
estimate
-0.00
54
428
5
11
4.57
1.94
1.8
1.5
—
—
—
0
0
6
16
3.77
1.93
1.8
1.9
25.83
25.33
umol/l
—
6
16
8
28
2.88
1.86
6.4
3.0
25.00
19.20
nmol/l
—
8
22
5
12
4.19
1.82
1.0
1.1
—
—
—
0
0
8
29
2.78
1.79
1.9
1.3
—
—
—
0
0
561
5917
0.82
1.76
89.1
20.8
104.65
134.13
g/l
148.54
546
5768
15
74
2.05
1.76
1.7
1.4
50.80
64.88
%
—
10
49
561
5916
0.82
1.75
88.4
20.6
8.67
6.91
e9/l
0.69
541
5680
561
5915
0.82
1.74
88.4
20.6
3.45
4.43
e12/l
123.66
539
5674
561
5915
0.82
1.74
88.1
20.5
31.38
30.44
pg
16.63
548
5766
561
5914
0.82
1.73
88.6
20.6
164.97
239.51
e9/l
32.67
539
5696
8
30
2.68
1.72
1.5
1.1
—
—
—
0
0
561
5913
0.82
1.72
88.6
20.7
31.57
39.65
%
93.86
509
5357
561
5912
0.82
1.71
88.3
20.6
95.19
91.59
fl
28.40
548
5764
11
48
2.31
1.71
4.0
3.0
—
—
—
0
0
408
4424
0.84
1.70
81.2
19.0
329.75
331.88
g/l
3.92
402
4370
11
49
2.26
1.64
1.3
1.8
0.31
1.84
g/24h
—
6
24
31
198
1.59
1.62
1.5
1.2
—
—
—
0
0
22
129
1.73
1.58
1.3
1.4
250.64
301.17
ug/g
0.57
14
77
220
1916
1.21
1.55
2.7
2.2
112.66
310.03
u/l
3.14
203
1782
11
52
2.13
1.45
1.4
1.3
—
—
—
0
0
5
16
3.14
1.44
4.0
1.4
6.90
4.06
nmol/l
—
5
16
9
39
2.32
1.43
1.0
1.1
—
—
—
0
0
83
656
1.30
1.39
3.0
2.5
3.17
6.49
ug/l
4.35
65
553
15
82
1.85
1.36
1.6
1.5
—
—
—
0
0
130
1091
1.23
1.33
3.2
2.3
2.43
2.45
mmol/l
1.02
120
922
5
18
2.79
1.28
1.0
1.0
1477.40
1819.33
miu/ml
—
5
18
62
480
1.32
1.23
1.3
1.3
—
—
—
0
0
14
239
0.58
1.23
1.2
1.4
—
—
—
0
0
12
64
1.89
1.18
1.6
1.3
—
—
—
0
0
54
417
1.32
1.11
4.6
3.5
—
—
—
0
0
12
206
0.58
1.09
26.9
10.8
—
—
—
0
0
529
5527
0.87
1.07
47.5
14.0
—
—
—
0
0
362
3877
0.88
1.06
6.2
4.2
—
—
—
0
0
8
147
0.54
1.04
1.1
1.1
—
—
—
0
0
544
5668
0.87
1.04
37.7
8.9
26.29
24.35
u/l
2.00
522
5380
9
47
1.93
1.02
2.0
1.1
—
—
—
0
0
9
47
1.93
1.02
2.0
1.1
—
—
—
0
0
58
459
1.28
1.01
2.8
3.8
66.55
93.84
ng/l
3.61
53
394
9
48
1.88
1.00
1.6
1.9
7.43
10.81
%
—
9
48
7
131
0.53
0.99
1.0
1.1
—
—
—
0
0
0
29
0.00
0.98
0.0
1.4
—
—
—
0
0
0
29
0.00
0.98
0.0
1.4
—
—
—
0
0
52
408
1.29
0.97
1.8
1.4
—
—
—
0
0
0
31
0.00
0.96
0.0
1.5
—
—
—
0
0
33
242
1.38
0.96
1.3
1.4
—
—
—
0
0
473
4957
0.88
0.93
5.1
4.5
2.03
2.00
mu/l
0.18
425
4419
165
1470
1.16
0.89
4.9
4.0
0.00
0.00
estimate
-0.00
51
414
8
42
1.91
0.88
1.4
1.6
—
—
—
0
0
33
246
1.36
0.88
2.2
2.3
211.64
598.15
ug/l
1.19
28
226
6
33
1.82
0.79
1.0
1.4
10.68
10.39
mmol/l
—
6
33
33
254
1.31
0.74
1.2
1.2
60.14
107.61
iu/ml
—
7
102
11
68
1.63
0.72
1.1
1.3
292.80
331.61
nmol/l
—
5
59
556
5378
1.12
0.71
64.0
14.3
32.88
25.99
mg/l
4.25
524
4250
5
26
1.93
0.70
1.6
1.4
—
—
—
0
0
5
95
0.52
0.66
2.2
1.4
—
—
—
0
0
170
1855
0.89
0.64
2.7
3.1
1181.67
154.41
mg/l
0.94
123
1196
5
29
1.73
0.64
1.2
2.0
53.32
56.95
umol/l
—
5
22
12
79
1.53
0.63
1.1
1.1
—
—
—
0
0
9
139
0.64
0.61
1.0
1.1
—
—
—
0
0
62
529
1.19
0.60
1.9
2.1
155.92
159.19
ug/g
0.03
51
404
181
1958
0.90
0.58
3.4
3.7
8.17
8.21
mg/mmol
0.00
119
1248
6
35
1.72
0.57
1.2
1.6
—
—
—
0
0
555
5699
0.91
0.56
61.5
17.7
4.02
4.01
mmol/l
0.33
542
5505
177
1913
0.90
0.56
2.8
3.1
6.77
7.35
mmol/l
0.97
156
1595
6
37
1.63
0.55
1.0
1.3
—
—
—
0
0
152
1393
1.11
0.55
4.2
3.5
—
—
—
0
0
24
187
1.29
0.53
5.0
4.6
—
—
—
0
0
17
126
1.36
0.52
1.9
2.6
—
—
—
0
0
7
45
1.56
0.49
9.6
13.9
—
—
—
0
0
556
5691
0.92
0.47
55.8
17.6
138.74
139.70
mmol/l
14.36
540
5501
5
31
1.62
0.43
1.2
1.5
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
0.75
—
0
6
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
15
0.00
0.41
0.0
6.8
—
—
—
0
0
8
60
1.34
0.40
2.1
1.6
—
—
—
0
0
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
7
101
0.69
0.39
1.9
1.4
—
—
—
0
0
7
101
0.69
0.39
1.9
1.4
—
—
—
0
0
37
316
1.18
0.39
1.1
1.3
—
—
—
0
0
16
202
0.79
0.37
2.8
2.0
—
—
—
0
0
11
146
0.75
0.36
3.0
2.6
—
—
—
0
0
5
76
0.66
0.36
2.2
1.4
—
—
—
0
0
5
80
0.62
0.35
1.4
1.7
—
—
—
0
0
87
797
1.10
0.35
1.3
1.3
23.48
35.49
iu/ml
1.20
24
251
13
101
1.29
0.32
2.9
2.3
—
—
—
0
0
35
397
0.88
0.29
2.5
3.2
—
—
—
0
0
13
103
1.27
0.28
2.9
2.3
3.95
4.07
mmol/l
0.45
13
103
13
103
1.27
0.28
2.9
2.3
106.85
105.00
mmol/l
1.03
13
103
224
2329
0.95
0.27
4.6
4.0
2.15
2.21
ug/l
0.10
195
2045
23
197
1.17
0.26
2.1
2.2
0.20
0.26
g/l
0.56
11
63
83
774
1.08
0.25
1.2
1.3
12.16
11.83
u/ml
0.01
24
283
11
87
1.27
0.24
1.5
1.7
318.82
292.04
mu/l
0.25
11
79
0
11
0.00
0.21
0.0
1.6
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
30.60
—
0
10
0
12
0.00
0.21
0.0
7.9
—
—
—
0
0
95
995
0.95
0.16
1.3
1.2
3.60
1.45
u/ml
0.45
19
263
8
99
0.81
0.13
1.8
1.4
—
—
—
0
0
8
100
0.80
0.13
1.9
1.4
—
—
—
0
0
31
335
0.92
0.13
5.2
3.7
—
—
—
0
0
14
158
0.88
0.12
2.1
2.2
140.90
81.15
ug/min
—
7
96
40
376
1.07
0.11
1.5
1.4
—
—
—
0
0
5
45
1.11
0.10
1.4
1.9
3.22
1.79
ug/l
—
5
36
133
1299
1.03
0.09
5.0
4.2
1.02
1.02
kg/l
0.04
21
213
6
70
0.86
0.07
1.0
1.1
—
20.74
—
0
11
7
84
0.83
0.07
1.9
2.0
174.29
232.71
pmol/l
—
7
78
36
352
1.02
0.01
1.2
1.2
—
—
—
0
0
10
94
1.06
0.01
1.2
1.2
—
—
—
0
0
20
194
1.03
0.00
1.1
1.1
—
111.83
titre
—
0
6
401
4003
1.00
0.00
4.4
3.6
14.81
15.06
pmol/l
0.90
358
3546
16
158
1.01
0.00
1.7
1.6
—
—
—
0
0
0
8
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
1.81
—
0
7
6
61
0.98
-0.00
2.8
1.5
—
—
—
0
0
7
78
0.90
-0.00
2.1
2.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
58
0.86
-0.00
3.2
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0

Mortality – FinRegistry

↥

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

↥

Index endpoint: C3_AML_MDS – Acute myeloid leukaemia and myelodysplastic syndromes

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).