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This is a non-core endpoint: only basic statistics are computed.

Myelodysplastic syndrome

C3_MYELODYSP_SYNDR

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 D46
  • Cancer registry: Topography ICD-O-3 ANY
  • Cancer registry: Morphology ICD-O-3 9980|998[2-7]|9989
  • Cancer registry: Behaviour codes 3

2 out of 7 registries used, show all original rules.

405

4. Check minimum number of events

None

405

5. Include endpoints

None

405

6. Filter based on genotype QC (FinnGen only)

385

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy
C
First used in FinnGen datafreeze
DF8

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 385 139 246
Unadjusted period prevalence (%) 0.09 0.05 0.11
Median age at first event (years) 77.51 77.74 77.38

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
405
Matched controls
4050
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
XW000
NOMESCO Finland
Bone marrow biopsy
74.5
307.7
214
60
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
170.4
307.7
230
31
D46.9
ICD-10 Finland
Myelodysplastic syndrome, unspecified
1378.4
274.5
237
*
9989/3-C42.1
ICD-O-3
Myelodysplastic syndrome, NOS, of bone marrow
+∞
274.2
231
*
WW500
NOMESCO Finland
Blood transfusion
67.7
267.5
153
36
D46.7
ICD-10 Finland
Other myelodysplastic syndromes
1049.4
199.3
179
*
D64.9
ICD-10 Finland
Anaemia, unspecified
15.7
181.8
237
333
B03XA02
ATC
darbepoetin alfa; parenteral
52.8
174.4
103
26
A04AA01
ATC
ondansetron; systemic, rectal
39.1
139.8
89
29
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
27.3
106.5
76
34
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
58.9
98.6
56
11
Z51.5
ICD-10 Finland
Palliative care
13.1
86.6
92
89
D46.2
ICD-10 Finland
Refractory anaemia with excess of blasts [RAEB]
+∞
81.0
75
*
L03AA02
ATC
filgrastim; parenteral
+∞
78.8
73
*
D46.1
ICD-10 Finland
Refractory anaemia with ring sideroblasts
631.5
57.1
55
*
D46.0
ICD-10 Finland
Refractory anaemia without ring sideroblasts, so stated
310.7
54.6
54
*
B03XA01
ATC
erythropoietin; parenteral
82.5
51.6
57
8
C92.0
ICD-10 Finland
Acute myeloblastic leukaemia [AML]
+∞
49.0
46
*
JN4AD
NOMESCO Finland
Body CT examination
8.6
48.6
68
93
A49.9
ICD-10 Finland
Bacterial infection, unspecified
5.3
47.9
121
300
D70.89
ICD-10 Finland
Neutropenic splenomegaly
113.8
47.0
50
5
9983/3-C42.1
ICD-O-3
Myelodysplastic syndrome with excess blasts of bone marrow
+∞
45.7
43
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
+∞
44.6
42
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
476.3
44.1
43
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
42.4
40
*
B82
ICPC
Anaemia other/unspecified
9.7
38.3
47
54
306
Kela drug reimbursment
Erythropoietin and darbepoetin
366.4
34.5
34
*
JN4BD
NOMESCO Finland
Extensive body CT
7.1
33.4
54
86
ZX112
NOMESCO Finland
Subcutaneous
53.7
33.2
39
8
R50.9
ICD-10 Finland
Fever, unspecified
4.3
33.1
107
315
9982/3-C42.1
ICD-O-3
Myelodysplastic syndrome with ring sideroblasts and single lineage dysplasia of bone marrow
+∞
32.7
31
*
ZX120
NOMESCO Finland
Intravenous
5.7
31.0
64
130
116
Kela drug reimbursment
Prostate cancer
+∞
30.6
29
*
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
11.9
30.6
32
29
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
277.4
26.0
26
*
127
Kela drug reimbursment
Transplant complication
74.8
25.1
28
*
D64.8
ICD-10 Finland
Other specified anaemias
10.7
25.0
28
28
N02AA05
ATC
oxycodone; systemic
3.4
24.7
113
414
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
24.2
23
*
L04AD01
ATC
ciclosporin; systemic
38.9
23.3
29
8
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.9
23.1
79
238
A04AA02
ATC
granisetron; systemic, transdermal
+∞
22.1
21
*
9861/3-C42.1
ICD-O-3
Acute myeloid leukemia, NOS, of bone marrow
+∞
22.1
21
*
L02AE02
ATC
leuprorelin; implant, parenteral
+∞
22.1
21
*
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
41.2
22.0
27
7
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
232.0
21.8
22
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.7
21.5
197
1046
SPAT1088
SPAT
Blood transfusion
39.5
21.0
26
7
WW200
NOMESCO Finland
Immunization
9.2
20.9
26
30
A03FA01
ATC
metoclopramide; systemic, rectal
3.6
20.5
78
252
V03AC03
ATC
deferasirox; oral
+∞
20.0
19
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
209.8
19.7
20
*
D46.4
ICD-10 Finland
Refractory anaemia, unspecified
209.8
19.7
20
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.6
19.4
227
1338
J01MA12
ATC
levofloxacin; systemic
2.9
19.1
116
493
J02AC03
ATC
voriconazole; systemic
105.0
18.7
20
*
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
4.7
18.3
45
105
H02AB06
ATC
prednisolone; systemic
2.5
18.0
230
1397
L03AA13
ATC
pegfilgrastim; parenteral
99.5
17.7
19
*
T86.0
ICD-10 Finland
Bone-marrow transplant rejection
187.9
17.7
18
*
9980/3-C42.1
ICD-O-3
Myelodysplastic syndrome with single lineage dysplasia of bone marrow
+∞
16.8
16
*
9985/3-C42.1
ICD-O-3
Myelodysplastic syndrome with multilineage dysplasia of bone marrow
+∞
16.8
16
*
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
7.7
16.7
24
33
WZC00
NOMESCO Finland
Treatment plan or consultation
2.7
16.2
114
519
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
4.6
15.9
40
95
WF002
NOMESCO Finland
Radical radiotherapy
62.6
15.9
18
*
A05AA02
ATC
ursodeoxycholic acid; oral
15.6
15.6
25
17
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.4
15.0
145
763
130
Kela drug reimbursment
Malignant tumour
+∞
14.7
14
*
115
Kela drug reimbursment
Breast cancer
+∞
14.7
14
*
175
Kela drug reimbursment
Deferasirox
+∞
14.7
14
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.8
14.5
47
135
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
5.8
14.5
27
49
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
+∞
13.6
13
*
WW306
NOMESCO Finland
Transfer of stem cells from foreign registered donator
+∞
13.6
13
*
M04AA01
ATC
allopurinol; systemic
2.5
13.6
105
496
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
4.6
12.9
31
71
TGC00
NOMESCO Finland
Bronchial lavation
5.5
12.6
25
48
B02AA02
ATC
tranexamic acid; systemic
3.4
12.3
48
156
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.1
12.1
190
1194
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.1
12.0
160
944
H02AB02
ATC
dexamethasone; systemic
12.2
12.0
21
18
A41.9
ICD-10 Finland
Sepsis, unspecified
3.9
12.0
36
98
Y84.8
ICD-10 Finland
Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
31.1
11.7
15
5
JN6AD
NOMESCO Finland
CT of torso and neck
23.7
11.7
16
7
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
4.6
11.6
28
64
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
+∞
11.5
11
*
9945/3-C42.1
ICD-O-3
Chronic myelomonocytic leukemia, NOS, of bone marrow
+∞
11.5
11
*
D46
ICD-10 Finland
Myelodysplastic syndromes
+∞
11.5
11
*
1BC07, ,
NOMESCO Finland
+∞
11.5
11
*
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
+∞
11.5
11
*
L02BB03
ATC
bicalutamide; oral
+∞
11.5
11
*
R04.0
ICD-10 Finland
Epistaxis
3.0
11.4
55
203
L01XX05
ATC
hydroxycarbamide; oral
8.6
11.0
23
28
A02BC02
ATC
pantoprazole; systemic
2.1
10.9
270
1981
D75.9
ICD-10 Finland
Disease of blood and blood-forming organs, unspecified
28.9
10.8
14
5
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.4
10.7
40
126
TPH04
NOMESCO Finland
Cathetrisation of vein
2.3
10.5
101
519
L02BG04
ATC
letrozole; oral
112.8
10.5
11
*
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
+∞
10.5
10
*
XW4XT
NOMESCO Finland
Biopsy of other inner organ with radiological guidance guidance
+∞
10.5
10
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
10.5
10
*
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
10.5
10
*
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
+∞
10.5
10
*
NEA10
NOMESCO Finland
Exploration of soft tissue of pelvis, percutaneous
33.5
10.4
13
*
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
11.7
10.2
18
16
L57.0
ICD-10 Finland
Actinic keratosis
2.9
10.1
52
198
TNE20
NOMESCO Finland
Bone marrow aspiration, pelvis
41.2
10.0
12
*
D47.1
ICD-10 Finland
Chronic myeloproliferative disease
26.8
9.9
13
5
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
4.4
9.8
25
60
NK6AN
NOMESCO Finland
Total body bone isotope imaging
56.4
9.7
11
*
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
4.2
9.7
26
65
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
11.8
9.6
17
15
UJF32
NOMESCO Finland
Coloscopy
2.1
9.6
109
596
D46.3
ICD-10 Finland
Refractory anemia with excess of blasts with transformation
102.3
9.5
10
*
Y77
ICPC
Malignant neoplasm prostate
102.3
9.5
10
*
J01MA02
ATC
ciprofloxacin; systemic
1.9
9.4
178
1168
WW302
NOMESCO Finland
Allogenic transfer of stem cells from relative
+∞
9.4
9
*
B74
ICPC
Malignant neoplasm blood other
+∞
9.4
9
*
C93.1
ICD-10 Finland
Chronic myelomonocytic leukaemia
+∞
9.4
9
*
WD515
NOMESCO Finland
Demanding therapy of malignancy with enzyme inhibitors and similar treatments
+∞
9.4
9
*
PJA12
NOMESCO Finland
Sentinel node biopsy
+∞
9.4
9
*
B73
ICPC
Leukaemia
+∞
9.4
9
*
HAC20
NOMESCO Finland
Total mastectomy
+∞
9.4
9
*
C90.0
ICD-10 Finland
Multiple myeloma
+∞
9.4
9
*
L04AA06
ATC
mycophenolic acid; systemic
11.8
9.1
16
14
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
3.4
9.1
34
107
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.4
9.1
67
306
J01MA14
ATC
moxifloxacin; systemic
2.8
9.0
49
192
C03CA01
ATC
furosemide; systemic
1.9
8.9
207
1445
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
51.1
8.7
10
*
GA4AT
NOMESCO Finland
Cathetrisation of pleural cavity with ultrasound guidance
16.7
8.6
13
8
J05AB11
ATC
valaciclovir; oral
2.4
8.5
64
294
9961/3-C42.1
ICD-O-3
Primary myelofibrosis of bone marrow
91.9
8.4
9
*
GD1AD
NOMESCO Finland
Thorax CT examination
3.5
8.4
29
87
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
8.4
8
*
C83.3
ICD-10 Finland
Diffuse large B-cell lymphoma
+∞
8.4
8
*
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
+∞
8.4
8
*
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
34.1
8.1
10
*
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
4.1
8.0
22
56
L04AD02
ATC
tacrolimus; systemic
45.9
7.7
9
*
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
3.0
7.6
35
125
B99
ICPC
Blood/lymph/spleen disease other
25.6
7.6
10
*
JN3AD
NOMESCO Finland
Abdominal CT examination
2.6
7.6
45
185
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.4
7.4
54
245
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
+∞
7.3
7
*
C67.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of bladder
+∞
7.3
7
*
8090/3-C44.5
ICD-O-3
Basal cell carcinoma, NOS, of skin of trunk
+∞
7.3
7
*
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
+∞
7.3
7
*
ZX070
NOMESCO Finland
Intensity modified radiotherapy
+∞
7.3
7
*
D61.9
ICD-10 Finland
Aplastic anaemia, unspecified
30.6
7.2
9
*
D64.0
ICD-10 Finland
Hereditary sideroblastic anaemia
30.6
7.2
9
*
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
3.6
7.1
23
66
UGC12
NOMESCO Finland
Flexible bronchoscopy
2.7
7.1
39
154
TPX10
NOMESCO Finland
Implantation of vascular injection port
5.6
7.0
19
35
XX3DW
NOMESCO Finland
Time consuming IT work
3.4
6.8
24
73
122
Kela drug reimbursment
Aplastic anaemia
40.8
6.8
8
*
D70.82
ICD-10 Finland
Drug-induced neutropenia
40.8
6.8
8
*
SPAT1255
SPAT
Intravenous administration of medicine
2.7
6.7
36
141
J01DB01
ATC
cefalexin; oral
1.8
6.6
295
2412
J02AC01
ATC
fluconazole; systemic
1.9
6.5
108
665
A07EA06
ATC
budesonide; oral, local oral
4.0
6.5
18
46
D47.2
ICD-10 Finland
Monoclonal gammopathy of undetermined significance (MGUS)
7.6
6.5
14
19
C44.41
ICD-10 Finland
Basocellular carcinoma of the skin of the scalp and neck
70.9
6.4
7
*
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
70.9
6.4
7
*
KCD02
NOMESCO Finland
Transurethral resection of bladder
14.6
6.4
10
7
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.9
6.3
86
496
KE1AT
NOMESCO Finland
Biopsy of prostata with ultrasoudnguidance
4.0
6.3
18
47
D53.1
ICD-10 Finland
Other megaloblastic anaemias, not elsewhere classified
18.4
6.3
9
5
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
3.8
6.3
19
52
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
6.3
6
*
C50.99
ICD-10 Finland
Breast, unspecified
+∞
6.3
6
*
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
6.3
6
*
L01BC06
ATC
capecitabine; oral
+∞
6.3
6
*
C20.91
ICD-10 Finland
Malignant tumor of the rectum invasive carcinoma
+∞
6.3
6
*
9986/3-C42.1
ICD-O-3
Myelodysplastic syndrome with isolated del (5q) of bone marrow
+∞
6.3
6
*
JA2AT
NOMESCO Finland
Abdominal puncture with ultrasound guidance
27.1
6.2
8
*
Z01.8
ICD-10 Finland
Other specified special examinations
1.9
6.2
90
531

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
178
20
158.00
307.65
1.4
1.1
—
—
—
0
0
164
39
69.99
286.96
3.2
1.4
—
—
—
0
0
121
17
101.08
230.60
1.8
1.1
—
—
—
0
0
230
307
16.02
183.19
6.6
2.0
70.89
65.31
e9/l
0.32
184
242
257
415
15.21
177.37
7.2
1.9
1.98
1.71
%
1.67
233
362
165
151
17.75
166.52
2.2
1.7
1.05
1.58
g/l
7.30
141
133
157
176
13.93
137.37
13.6
3.5
1.70
0.91
%
1.80
143
55
155
240
9.84
104.09
2.2
1.7
65.81
66.48
g/l
0.42
145
208
127
154
11.56
103.15
14.5
3.6
0.94
0.60
%
0.57
115
47
86
55
19.58
103.09
1.9
1.2
—
—
—
0
0
125
166
10.45
94.28
14.2
3.6
0.22
0.07
%
1.22
112
45
58
20
33.68
88.52
14.3
3.5
—
—
—
0
0
135
216
8.88
86.92
2.1
1.4
—
—
—
0
0
115
160
9.64
82.96
14.8
3.6
0.91
0.03
%
2.56
101
40
56
28
23.05
74.40
1.1
1.3
—
—
—
0
0
83
86
11.88
74.20
2.0
1.2
5.33
1.41
ratio
—
7
9
83
89
11.47
72.39
2.0
1.2
55.57
59.74
mg/l
0.13
75
71
82
89
11.30
70.86
2.0
1.2
63.54
41.44
mg/l
0.29
72
72
100
151
8.47
66.57
2.9
1.9
11.33
11.33
g/l
0.00
92
134
78
86
10.99
66.50
1.4
1.2
—
—
—
0
0
159
399
5.91
63.85
2.6
2.4
39.96
22.15
%
12.09
133
335
175
487
5.57
62.25
2.6
2.3
18.77
12.07
umol/l
11.61
167
436
161
427
5.60
60.31
2.6
2.3
1.90
2.20
g/l
9.84
156
386
282
1181
5.57
60.29
30.6
5.0
—
—
—
0
0
51
36
16.06
57.18
1.3
1.1
—
—
—
0
0
273
1166
5.12
55.44
23.3
4.8
0.74
0.63
%
1.28
260
1065
277
1213
5.06
54.00
27.2
5.1
10.73
8.80
%
3.89
264
1110
276
1208
5.03
53.77
24.7
4.8
1.92
2.92
%
5.53
263
1105
46
30
17.17
53.67
1.4
1.1
—
—
—
0
0
90
152
7.33
53.60
1.4
1.4
—
—
—
0
0
93
163
7.11
53.48
1.5
1.3
—
—
—
0
0
82
126
7.91
53.20
1.7
1.3
1.18
1.04
g/l
0.46
76
112
278
1233
5.00
52.96
25.8
5.0
31.55
24.74
%
9.43
264
1131
43
26
18.38
52.05
1.4
1.1
283.93
314.20
u/ml
—
27
10
60
64
10.83
51.98
2.0
1.2
—
—
—
0
0
104
212
6.26
51.32
1.4
1.5
—
—
—
0
0
214
804
4.52
50.22
19.3
2.1
—
—
—
0
0
205
747
4.53
50.11
5.5
2.5
2591.76
10486.95
umol/l
1.78
192
630
270
1218
4.65
49.04
22.2
4.8
49.55
59.76
%
17.31
254
1121
74
114
7.72
47.70
1.8
1.3
11.93
10.81
g/l
0.73
66
97
222
904
4.22
45.58
9.6
3.9
—
—
—
0
0
214
851
4.21
45.40
2.9
2.1
2.99
3.00
mg/l
0.01
186
706
50
7
81.06
45.15
2.8
1.1
—
—
—
0
0
245
1097
4.12
43.29
5.4
2.6
556.00
138.81
ug/l
16.43
226
978
255
1175
4.16
43.19
18.6
2.3
—
—
—
0
0
132
386
4.59
42.13
6.9
4.4
1.11
1.01
mmol/l
2.39
125
344
169
609
4.05
40.34
18.2
2.0
—
—
—
0
0
272
1354
4.07
40.15
22.9
4.7
0.11
0.21
e9/l
14.92
240
1170
61
92
7.63
39.83
1.9
1.3
37.52
35.43
g/l
1.31
53
75
71
127
6.57
39.50
2.1
1.6
4.65
2.43
ug/l
0.22
59
105
48
56
9.59
38.66
1.3
1.2
—
—
—
0
0
265
1325
3.89
38.19
20.3
4.7
1.39
1.75
e9/l
9.66
239
1153
269
1371
3.86
37.36
17.8
3.5
15.17
12.63
umol/l
2.49
259
1264
132
419
4.19
37.27
6.2
2.1
0.80
0.82
mmol/l
1.31
123
382
261
1307
3.80
37.19
19.3
4.6
0.64
0.63
e9/l
0.09
234
1111
261
1311
3.79
36.92
19.3
4.6
0.03
0.04
e9/l
1.71
233
1120
43
46
10.34
36.87
4.8
1.5
—
—
—
0
0
278
1457
3.90
36.79
37.4
5.2
3.59
4.56
e9/l
0.99
256
1260
184
796
3.40
31.81
2.2
1.8
1275.84
1162.03
nmol/l
0.72
141
598
37
13
31.15
28.13
1.4
1.3
—
—
—
0
0
246
1331
3.16
28.05
10.7
4.8
1.19
1.21
mmol/l
3.90
221
1175
262
1477
3.19
27.65
12.6
5.4
1.20
1.21
mmol/l
2.95
220
1258
37
14
28.92
27.61
2.8
2.7
—
—
—
0
0
117
412
3.59
27.52
1.9
2.0
—
—
—
0
0
122
477
3.23
23.89
3.1
1.7
29.82
29.93
s
0.05
116
457
227
1275
2.78
22.45
9.6
3.5
32.77
34.70
g/l
4.05
208
1163
169
853
2.68
20.14
2.3
1.6
18.68
20.01
nmol/l
0.57
156
718
24
6
42.40
19.72
5.8
1.0
—
—
—
0
0
104
411
3.06
19.60
1.5
1.2
2.63
2.82
g/l
0.35
83
226
232
1401
2.54
18.57
3.1
2.1
92.10
91.39
pmol/l
0.08
161
713
164
871
2.48
16.97
9.0
3.0
7.42
7.40
ph
2.05
30
143
16
0
+∞
16.78
1.0
0.0
—
—
—
0
0
15
0
+∞
15.72
1.0
0.0
—
—
—
0
0
15
0
+∞
15.72
1.0
0.0
—
—
—
0
0
15
0
+∞
15.72
1.0
0.0
—
—
—
0
0
15
0
+∞
15.72
1.0
0.0
—
—
—
0
0
120
573
2.55
15.35
2.2
1.6
2.22
1.25
mg/l
2.11
105
451
124
605
2.51
15.12
26.4
3.9
—
—
—
0
0
27
27
10.63
14.19
1.2
1.0
—
—
—
0
0
119
593
2.43
13.69
2.1
1.3
—
—
—
0
0
134
708
2.33
13.47
2.5
1.6
—
—
—
0
0
60
212
3.15
13.42
1.9
1.8
0.18
0.19
g/l
0.52
51
190
72
286
2.85
13.09
8.0
3.9
—
—
—
0
0
47
145
3.54
13.04
2.3
1.4
3.25
2.78
ug/l
0.25
36
116
72
287
2.83
13.00
1.5
1.2
528.00
600.58
titre
0.14
20
69
12
0
+∞
12.56
1.1
0.0
—
—
—
0
0
50
169
3.23
12.01
7.2
3.0
6.54
5.53
e9/l
0.12
33
124
15
7
22.18
10.75
1.1
1.1
—
—
—
0
0
282
2108
2.11
10.72
23.2
5.0
80.26
78.17
u/l
0.41
268
1899
245
1752
2.01
10.38
9.4
4.0
7.21
6.96
mmol/l
0.88
233
1627
38
120
3.39
10.15
7.7
4.9
25.90
24.98
mmol/l
0.83
32
111
225
1570
1.97
10.14
13.4
20.5
1.37
1.45
inr
0.44
56
456
14
7
20.65
9.86
1.1
1.1
—
—
—
0
0
22
31
7.44
9.64
1.2
1.0
—
—
—
0
0
19
37
5.34
9.45
1.5
1.5
—
—
—
0
0
144
881
1.98
9.33
2.6
2.1
48.35
61.58
u/l
1.61
128
800
71
330
2.40
9.25
2.0
1.8
—
—
—
0
0
65
300
2.39
8.57
3.2
1.4
—
—
—
0
0
20
31
6.73
8.29
1.0
1.1
—
—
—
0
0
174
1173
1.85
8.16
4.2
3.1
2752.15
2091.50
ng/l
0.86
161
1015
14
12
12.03
8.13
1.1
1.0
—
—
—
0
0
51
216
2.56
8.07
6.6
4.0
5.27
5.19
kpa
0.16
44
207
50
211
2.56
7.97
6.6
4.1
7.43
7.39
ph
—
7
25
88
474
2.09
7.96
4.0
2.9
1.64
2.28
e6/l
0.53
44
266
129
797
1.91
7.90
4.7
2.9
—
—
—
0
0
18
40
4.66
7.72
1.4
1.5
663.42
1949.52
e6/l
1.07
12
29
11
6
18.79
7.64
1.0
1.0
—
—
—
0
0
144
932
1.85
7.57
4.7
3.1
393.74
143.30
e6/l
0.53
116
720
24
69
3.63
7.38
1.5
1.4
1.00
1.07
g/l
0.45
24
64
26
80
3.40
7.24
1.3
1.3
—
—
—
0
0
10
5
20.45
7.16
1.0
1.0
—
—
—
0
0
67
339
2.17
7.08
1.3
1.2
—
—
—
0
0
156
1053
1.78
7.04
5.8
3.6
73.12
120.30
e6/l
0.69
122
768
10
6
17.05
6.77
1.0
1.0
14.13
17.03
umol/l
—
10
6
260
2043
1.76
6.77
6.3
4.1
25.86
14.07
mm/h
10.55
237
1812
130
840
1.81
6.74
4.9
2.9
0.55
0.45
e6/l
0.25
102
639
21
59
3.70
6.68
1.8
2.1
34.36
36.29
umol/l
0.10
14
52
251
1957
1.74
6.67
6.7
4.3
—
—
—
0
0
11
9
12.52
6.61
1.5
1.2
—
—
—
0
0
12
12
10.26
6.57
2.3
1.5
36.14
51.71
%
—
7
7
6
0
+∞
6.26
1.3
0.0
7.00
—
%
—
6
0
17
33
5.33
6.08
1.5
1.6
39528.75
10167.95
e6/l
—
8
21
62
325
2.07
5.95
3.6
2.9
1.23
2.03
mmol/l
0.72
53
273
16
40
4.12
5.95
3.0
2.9
—
—
—
0
0
17
34
5.17
5.94
1.6
1.5
—
—
—
0
0
14
22
6.55
5.91
1.2
1.1
—
—
—
0
0
163
1161
1.68
5.81
39.4
8.1
0.35
0.00
e9/l
0.59
138
941
24
81
3.09
5.79
3.1
3.7
—
—
—
0
0
144
1001
1.68
5.58
5.2
3.3
—
—
—
0
0
49
243
2.16
5.42
8.3
5.6
—
—
—
0
0
69
389
1.93
5.39
6.8
5.3
1.20
1.39
mmol/l
0.12
56
300
46
223
2.20
5.38
2.3
2.0
38.25
30.20
u/l
0.67
36
180
36
157
2.42
5.37
7.6
4.2
—
—
—
0
0
101
656
1.72
4.96
3.5
2.4
5.66
4.17
e6/l
1.17
92
585
195
1503
1.57
4.78
3.5
3.0
78.94
51.04
u/l
2.28
172
1351
98
640
1.70
4.69
3.8
2.8
513.35
547.88
mosm/kgh2o
1.10
86
532
12
22
5.59
4.63
1.0
1.0
—
—
—
0
0
8
8
10.17
4.54
1.6
1.0
—
—
—
0
0
33
150
2.31
4.51
7.5
7.6
—
—
—
0
0
46
240
2.03
4.47
2.2
1.5
358.30
371.07
nmol/l
0.14
46
211
15
45
3.42
4.36
5.9
1.4
36.93
35.59
u/ml
0.02
15
45
17
56
3.12
4.29
2.3
3.2
—
—
—
0
0
29
128
2.36
4.24
1.3
1.3
—
—
—
0
0
10
17
6.00
4.15
1.5
1.5
—
—
—
0
0
7
7
10.15
4.02
11.9
1.1
—
—
—
0
0
13
32
4.16
3.93
1.5
1.6
—
—
—
0
0
36
181
2.09
3.87
1.9
1.1
—
—
—
0
0
149
1125
1.51
3.79
2.4
2.2
78.50
78.83
nmol/l
0.05
129
952
6
5
12.15
3.77
1.7
1.0
—
—
—
0
0
14
39
3.68
3.73
11.8
2.8
57.57
61.49
%
0.44
14
39
131
967
1.52
3.68
3.5
2.1
2.30
2.35
mmol/l
2.80
110
792
8
13
6.25
3.51
1.0
1.2
14.98
12.12
ug/l
—
8
13
9
18
5.09
3.39
1.3
1.2
—
—
—
0
0
16
59
2.78
3.36
1.6
1.4
—
—
—
0
0
108
780
1.52
3.32
1.7
1.8
149398138.22
6359723.18
pmol/l
0.47
83
629
167
1321
1.45
3.25
5.9
4.3
31.09
47.30
ng/l
3.11
136
1022
12
35
3.50
3.13
1.2
2.0
0.60
1.21
g/l
—
7
28
9
20
4.58
3.13
2.9
2.8
—
—
—
0
0
14
50
2.86
3.12
2.1
1.7
9.79
18.32
u/ml
1.34
14
34
21
93
2.33
3.09
2.5
3.5
0.81
0.92
nmol/l
0.61
13
73
16
62
2.65
3.08
6.2
3.1
—
—
—
0
0
31
162
1.99
3.04
9.5
6.6
23.55
24.32
mmol/l
0.38
31
152
93
664
1.52
2.99
5.3
3.9
—
—
—
0
0
20
88
2.34
2.98
7.9
3.2
7.44
7.42
ph
0.86
15
80
42
246
1.79
2.93
4.1
4.0
—
—
—
0
0
9
22
4.16
2.90
3.2
2.6
—
—
—
0
0
12
38
3.22
2.87
2.2
1.5
88.85
90.32
%
0.50
12
38
95
690
1.49
2.81
4.4
4.2
64.82
279.09
ng/l
2.59
83
606
7
14
5.07
2.74
2.7
3.4
—
—
—
0
0
168
1368
1.39
2.65
5.4
4.0
0.00
0.00
estimate
-0.00
34
249
8
20
4.06
2.58
1.3
1.4
—
—
—
0
0
46
288
1.67
2.56
4.8
3.1
—
—
—
0
0
7
16
4.43
2.48
1.1
1.2
—
—
—
0
0
49
728
0.63
2.43
2.4
3.4
—
—
—
0
0
8
22
3.69
2.37
1.0
1.2
—
—
—
0
0
7
18
3.94
2.26
1.1
1.1
—
—
—
0
0
21
107
2.02
2.25
2.1
1.8
—
—
—
0
0
165
1369
1.35
2.22
7.4
5.3
0.00
0.00
estimate
-0.00
29
223
13
54
2.45
2.22
1.7
1.5
—
—
—
0
0
5
9
5.61
2.22
1.4
1.0
—
—
—
0
0
38
236
1.67
2.20
1.3
1.3
—
—
—
0
0
167
1391
1.34
2.18
5.4
4.0
0.00
0.00
estimate
-0.00
25
224
298
2706
1.38
2.18
56.2
15.2
30.38
26.98
mg/l
0.89
278
2174
7
20
3.54
2.06
1.0
1.2
201.71
79.22
pmol/l
—
7
20
30
179
1.73
2.02
2.7
2.9
0.40
0.24
e6/l
0.46
30
174
9
32
2.85
2.01
1.4
1.2
—
—
—
0
0
52
359
1.51
1.96
3.3
2.5
2.46
5.36
ug/l
6.25
35
305
16
78
2.09
1.93
1.3
1.2
—
—
—
0
0
117
941
1.34
1.89
5.9
4.3
—
—
—
0
0
30
183
1.69
1.88
3.8
2.5
—
—
—
0
0
14
67
2.13
1.78
3.6
2.1
11.67
15.64
%
—
8
34
53
378
1.46
1.72
2.8
3.2
297.32
290.96
ng/l
0.03
45
350
5
13
3.88
1.72
1.2
1.1
—
—
—
0
0
12
237
0.49
1.67
1.4
1.5
—
—
—
0
0
6
19
3.19
1.66
2.0
1.2
—
—
—
0
0
54
728
0.70
1.64
2.8
2.8
0.75
0.81
ug/l
0.26
34
504
247
2700
0.78
1.61
4.5
5.4
2.05
2.51
mmol/l
12.77
210
2410
26
161
1.66
1.57
1.2
1.2
—
—
—
0
0
223
1995
1.26
1.53
3.9
3.5
14.89
15.11
pmol/l
0.48
194
1748
23
141
1.67
1.45
5.9
3.2
—
—
—
0
0
10
46
2.20
1.41
1.1
1.1
—
—
—
0
0
118
987
1.28
1.40
2.3
2.1
97.10
312.06
u/l
2.10
108
909
237
2582
0.80
1.37
6.2
6.7
40.31
41.51
mmol/mol
0.95
212
2332
12
62
1.96
1.29
1.2
1.3
217.29
313.25
ug/g
—
7
36
13
70
1.89
1.25
1.6
1.2
—
—
—
0
0
24
156
1.57
1.23
1.1
1.3
—
—
—
0
0
6
26
2.33
1.19
1.8
1.5
8.68
11.57
%
—
6
26
240
2583
0.83
1.09
4.1
4.7
1.27
1.42
mmol/l
4.83
203
2298
19
122
1.58
1.04
1.5
1.2
93.32
231.14
u/ml
1.66
19
113
18
114
1.61
1.04
1.7
1.2
—
—
—
0
0
9
48
1.89
1.01
1.6
1.8
—
—
—
0
0
245
2616
0.84
0.95
4.1
4.7
3.70
4.35
mmol/l
15.62
206
2350
58
468
1.28
0.93
1.2
1.2
6.01
1.91
u/ml
—
10
116
6
28
2.16
0.92
2.8
1.4
12.78
21.84
%
—
6
20
6
28
2.16
0.92
1.3
1.0
—
—
—
0
0
12
71
1.71
0.89
1.4
1.3
—
—
—
0
0
6
113
0.52
0.84
42.7
11.3
—
—
—
0
0
90
776
1.21
0.81
5.9
4.2
0.00
0.00
estimate
-0.00
26
219
5
24
2.10
0.74
1.2
1.2
—
—
—
0
0
5
25
2.01
0.73
1.8
1.4
—
—
—
0
0
48
394
1.25
0.69
1.3
1.3
33.65
45.64
iu/ml
0.46
11
112
7
42
1.68
0.68
1.1
1.1
—
—
—
0
0
45
368
1.25
0.67
1.2
1.2
21.32
14.73
u/ml
0.15
13
123
8
49
1.65
0.62
2.5
1.7
56.63
66.92
%
—
8
49
29
228
1.29
0.60
5.7
3.4
—
—
—
0
0
11
72
1.54
0.59
2.2
2.3
—
—
—
0
0
11
73
1.52
0.56
2.8
2.6
—
—
—
0
0
237
2487
0.89
0.56
4.5
4.2
1.16
1.25
mmol/l
1.39
202
2180
7
45
1.57
0.49
1.3
1.1
—
—
—
0
0
299
2904
1.11
0.40
51.3
18.7
138.70
139.69
mmol/l
8.19
288
2792
193
2023
0.91
0.39
5.6
4.2
—
—
—
0
0
299
2911
1.10
0.36
54.3
18.8
4.04
4.03
mmol/l
0.40
290
2802
8
65
1.24
0.27
2.3
2.4
—
—
—
0
0
8
67
1.20
0.26
2.3
2.4
4.04
4.11
mmol/l
—
8
67
8
67
1.20
0.26
2.3
2.4
106.50
104.94
mmol/l
—
8
67
19
160
1.20
0.26
1.8
2.5
—
26.14
—
0
5
77
723
1.08
0.22
5.0
3.7
—
—
—
0
0
283
2775
1.07
0.21
45.7
14.9
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
27.18
—
0
11
0
12
0.00
0.21
0.0
1.1
—
145.08
—
0
12
0
14
0.00
0.20
0.0
5.9
—
25.08
—
0
14
22
193
1.15
0.20
1.3
1.5
—
—
—
0
0
264
2691
0.95
0.19
5.7
5.0
6.13
6.16
mmol/l
0.11
223
2374
13
109
1.20
0.19
4.8
4.6
—
—
—
0
0
108
1035
1.06
0.18
3.8
3.7
10.49
7.65
mg/mmol
0.30
72
653
72
681
1.07
0.17
6.0
4.3
1.02
1.02
kg/l
0.15
12
111
256
2513
1.05
0.16
4.9
4.4
2.10
2.01
mu/l
0.58
223
2208
300
2958
1.05
0.16
85.3
21.8
96.54
91.98
fl
19.22
291
2873
300
2959
1.05
0.15
85.7
21.8
171.99
234.79
e9/l
10.73
284
2847
300
2960
1.05
0.15
85.5
21.8
30.71
39.38
%
58.30
271
2666
300
2960
1.05
0.15
85.0
21.7
31.61
30.54
pg
9.35
291
2875
300
2960
1.05
0.15
85.5
21.8
7.35
6.99
e9/l
0.16
286
2830
300
2960
1.05
0.15
85.4
21.8
3.29
4.40
e12/l
86.29
284
2827
300
2961
1.05
0.14
86.5
22.0
101.18
133.50
g/l
100.25
289
2874
11
95
1.16
0.11
3.0
2.1
0.15
0.23
g/l
—
5
29
101
978
1.04
0.11
3.1
3.0
6.30
7.27
mmol/l
1.65
86
801
289
2857
1.04
0.11
30.6
9.0
24.18
24.15
u/l
0.01
274
2689
10
87
1.15
0.09
3.2
2.1
—
—
—
0
0
15
136
1.11
0.08
1.0
1.3
—
48.58
—
0
10
5
65
0.77
0.08
1.2
1.0
—
—
—
0
0
7
64
1.10
0.08
1.0
1.1
—
—
—
0
0
136
1338
1.02
0.06
4.7
4.1
2.14
2.24
ug/l
0.16
115
1169
99
974
1.02
0.04
2.8
3.1
639.84
250.01
mg/l
0.29
73
628
21
204
1.03
0.00
2.8
3.3
—
—
—
0
0
19
191
0.99
0.00
1.9
1.5
—
—
—
0
0
18
175
1.03
0.00
5.1
4.1
—
—
—
0
0
0
5
0.00
0.00
0.0
6.2
—
919.20
—
0
5
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
7.0
—
1328.40
—
0
5
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
7.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.4
—
42866.67
—
0
9
0
8
0.00
-0.00
0.0
7.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
68
0.88
-0.00
3.2
3.1
—
—
—
0
0
8
80
1.00
-0.00
1.9
1.6
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: C3_MYELODYSP_SYNDR – Myelodysplastic syndrome

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).