Congenital deformities of feet

Q17_CONGEN_DEFORMITI_FEET

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 Q66
  • Cause of death: ICD-10 Q66

2 out of 7 registries used, show all original rules.

976

4. Check minimum number of events

None

976

5. Include endpoints

None

976

6. Filter based on genotype QC (FinnGen only)

976

Control definitions (FinnGen only)

Control exclude
Q17_CONGEN_MALFO_DEFORMAT_MUSCULOS_SYSTEM

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
Q6[5-9]|Q7
Name in latin
Deformitates congenitae pedum

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 12688 5897 6770
Only index persons 10876 5130 5746
Unadjusted period prevalence (%)
Whole population 0.18 0.17 0.19
Only index persons 0.20 0.19 0.22
Median age at first event (years)
Whole population 10.23 12.31 8.35
Only index persons 12.68 14.50 11.06

-FinnGen-

Key figures

All Female Male
Number of individuals 976 606 370
Unadjusted period prevalence (%) 0.19 0.21 0.16
Median age at first event (years) 36.82 38.46 34.14

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
870
Matched controls
8700
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q66.7
ICD-10 Finland
Pes cavus
3428.5
285.6
260
*
Q66.0
ICD-10 Finland
Talipes equinovarus
2797.3
215.9
200
*
Q66.5
ICD-10 Finland
Congenital pes planus
321.0
160.4
158
6
Q66.8
ICD-10 Finland
Other congenital deformities of feet
+∞
117.4
110
*
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
7.7
79.2
201
326
Q66.9
ICD-10 Finland
Congenital deformity of feet, unspecified
277.1
75.7
76
*
Q66.2
ICD-10 Finland
Metatarsus varus
+∞
72.9
69
*
NHK40
NOMESCO Finland
Osteotomy or rotation osteotomy of II-V metatarsal or tarsal bone
28.0
67.6
93
37
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
6.3
49.0
140
257
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
7.8
48.8
118
171
Q66.4
ICD-10 Finland
Talipes calcaneovalgus
+∞
47.3
45
*
NHU20
NOMESCO Finland
Removal of internal fixation device from ankle or foot
9.7
45.6
96
110
7545B
ICD-9 Finland
Certain congenital musculoskeletal deformities, Varus deformities of feet[TALIPES EQUINOVARUS CONGENITUS]
+∞
45.2
43
*
NHL68
NOMESCO Finland
Tenodesis, shortening or lengthening of tendon of foot
23.7
44.7
64
29
NHL14
NOMESCO Finland
Shortening or lengthening of achilles tendon
29.6
39.5
53
19
NHK30
NOMESCO Finland
Osteotomy or rotation osteotomy of first metatarsal or tarsal bone
8.9
37.8
83
102
M21.4
ICD-10 Finland
Flat foot [pes planus] (acquired)
9.2
36.4
78
92
Q66.6
ICD-10 Finland
Other congenital valgus deformities of feet
361.0
35.2
35
*
NHG22
NOMESCO Finland
Fusion of subtalar joint
30.3
34.6
46
16
75400
ICD-8 Finland
Clubfoot (congenital), Pes equino-varus adductus
93.8
33.0
36
*
NHG24
NOMESCO Finland
Fusion of subtalar joint and between bones of ankle
55.1
31.5
37
7
M21.5
ICD-10 Finland
Acquired clawhand, clubhand, clawfoot and clubfoot
165.8
30.9
32
*
9341
FHL
Reduction and plaster or plaster exchange
+∞
30.4
29
*
TNH36
NOMESCO Finland
Custom molded cast of pes equinovarus
+∞
30.4
29
*
M20.1
ICD-10 Finland
Hallux valgus (acquired)
4.6
30.1
110
263
NHK99
NOMESCO Finland
Other operation on bone of ankle or foot
13.8
29.5
51
39
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
7.1
28.7
72
109
M20.4
ICD-10 Finland
Other hammer toe(s) (acquired)
7.6
28.1
67
94
NHL99
NOMESCO Finland
Other operation on muscle or tendon of ankle or foot
19.9
26.7
40
21
TNX92
NOMESCO Finland
Supporting bandage or orthosis of lower limb
11.5
26.6
50
46
NH1AD
NOMESCO Finland
Ankle and foot CT
9.9
26.6
54
58
Q66.3
ICD-10 Finland
Other congenital varus deformities of feet
+∞
26.2
25
*
NH3FA
NOMESCO Finland
Weight-bearing X-ray of foot
11.5
26.1
49
45
TNH33
NOMESCO Finland
Custom moulded brace, ankle or foot
13.2
24.6
43
34
9343
FHL
Posterior release or posteromedical release
+∞
24.1
23
*
NH1BG
NOMESCO Finland
Ankle and foot MRI examination with high intensity magnet
8.4
23.8
53
67
L17
ICPC
Foot/toe symptom/complaint
2.3
22.6
265
1399
M19.0
ICD-10 Finland
Primary arthrosis of other joints
3.9
22.5
99
280
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.9
21.3
144
558
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
5.8
21.2
61
111
NHT62
NOMESCO Finland
Surgical procedure for correction of pes equinovarus
+∞
20.9
20
*
SPAT1229
SPAT
Assessment of need for aid
4.5
20.9
77
185
NH1EA
NOMESCO Finland
Ankle X-ray examination with load or wrench
26.2
20.5
28
11
ZXA00
NOMESCO Finland
Right side
2.3
20.4
223
1127
B01AB05
ATC
enoxaparin; parenteral
2.3
20.4
227
1159
M79.6
ICD-10 Finland
Pain in limb
2.1
20.2
320
1911
M19.2
ICD-10 Finland
Other secondary arthrosis
11.7
20.1
37
33
L16
ICPC
Ankle symptom/complaint
2.8
20.1
144
578
TNX50
NOMESCO Finland
Removal of cutom molded cast and internal stretch
4.3
19.4
74
184
WX320
NOMESCO Finland
Spinalanesthesy
2.4
19.1
184
873
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.2
18.5
237
1285
NHG26
NOMESCO Finland
Fusion between bones of ankle or ankle and foot
13.9
18.3
31
23
NHL20
NOMESCO Finland
Myotomy or tenotomy of foot
25.7
18.3
25
10
NH1CG
NOMESCO Finland
Ankle and foot extensive MRI examination with high intensity magnet
8.3
18.2
40
50
NH3EA
NOMESCO Finland
Feet X-ray examination with load
8.3
18.2
40
50
TQW40
NOMESCO Finland
Remowal of suture of skin
3.6
17.9
83
245
L84
ICD-10 Finland
Corns and callosities
6.0
17.8
49
85
ZXA05
NOMESCO Finland
Left side
2.2
17.5
197
1003
NHG80
NOMESCO Finland
Fusion of first tarsometatarsal joint
6.1
17.5
48
83
NH1FA
NOMESCO Finland
Weight-bearing X-ray of ankle
14.2
17.4
29
21
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
4.3
17.1
65
161
N02BE01
ATC
paracetamol; systemic, rectal
2.0
17.1
689
5670
Q66.1
ICD-10 Finland
Talipes calcaneovarus
173.1
16.5
17
*
N02AX02
ATC
tramadol; systemic, rectal
1.9
16.0
306
1923
G60.0
ICD-10 Finland
Hereditary motor and sensory neuropathy
34.1
15.8
20
6
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.8
15.6
360
2413
M77.4
ICD-10 Finland
Metatarsalgia
3.5
15.0
72
219
N03AX16
ATC
pregabalin; oral
2.2
14.9
180
940
NHG20
NOMESCO Finland
Fusion of talocrural joint
21.5
14.7
21
10
R4110
NOMESCO Finland
Physiotherapy
2.0
14.4
221
1271
-
ICD-10 Finland
NA
7.2
14.2
34
49
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.7
14.2
102
409
M19.1
ICD-10 Finland
Post-traumatic arthrosis of other joints
6.7
14.0
35
54
N02AJ06
ATC
codeine and paracetamol; systemic
1.8
13.8
310
2038
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
2.7
13.8
100
403
M25.5
ICD-10 Finland
Pain in joint
1.9
13.7
252
1545
L82
ICPC
Congenital anomaly musculoskeletal
76.3
13.6
15
*
M21.6
ICD-10 Finland
Other acquired deformities of ankle and foot
26.2
13.4
18
7
TNH31
NOMESCO Finland
Prefabricated orthosis, ankle or foot
7.4
13.3
31
43
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
3.4
13.3
65
201
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.9
12.9
80
293
NHL30
NOMESCO Finland
Suture or reinsertion of tendon of foot
14.3
12.8
21
15
Z50.1
ICD-10 Finland
Other physical therapy
3.7
12.7
56
160
NHK10
NOMESCO Finland
Incision or excision of metatarsal or tarsal bone
11.2
12.6
23
21
N03AX12
ATC
gabapentin; oral
2.3
12.5
119
554
Z31.5
ICD-10 Finland
Genetic counselling
3.1
12.1
68
231
SPAT1225
SPAT
Implementation of podiatry rehabilitation plan
5.9
11.7
32
56
S18
ICPC
Laceration/cut
1.7
11.7
309
2112
NH1AI
NOMESCO Finland
Cone beam CT of ankle
30.5
11.7
15
5
NHG77
NOMESCO Finland
Arthroplasty of interphalangeal tarsal joint(s)
5.6
11.3
32
59
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
5.5
10.8
31
58
TNH32
NOMESCO Finland
Custom moulded split, ankle or foot
13.1
10.7
18
14
NHT99
NOMESCO Finland
Other operation on ankle or foot
60.7
10.6
12
*
NGA30
NOMESCO Finland
Exploration of knee joint, arthroscopic
3.6
10.6
47
136
TNX34
NOMESCO Finland
Major custom molded cast, unspecified region
6.3
10.5
27
44
M20.5
ICD-10 Finland
Other deformities of toe(s) (acquired)
12.2
10.4
18
15
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
3.5
10.3
47
139
NHG82
NOMESCO Finland
Fusion of other tarsal joint
9.7
10.3
20
21
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.3
10.1
92
419
9111
FHL
Plastering under anesthesia
16.9
9.9
15
9
NGL66
NOMESCO Finland
Transposition of tendon of knee or lower leg
26.3
9.8
13
5
Q87.88
ICD-10 Finland
Other specified congenital malformation syndromes, not elsewhere classified
26.3
9.8
13
5
NGK30
NOMESCO Finland
Angulation, rotation or displacement osteotomy of knee or lower leg
20.3
9.8
14
7
NHM10
NOMESCO Finland
Fasciotomy of ankle or foot
13.6
9.7
16
12
NH3BG
NOMESCO Finland
MRI of foot
10.2
9.5
18
18
TNX99
NOMESCO Finland
Other orthopaedic minor procedure
4.1
9.5
36
91
S83.0
ICD-10 Finland
Dislocation of patella
4.1
9.4
35
87
J01FF01
ATC
clindamycin; systemic
1.7
9.4
203
1289
7545A
ICD-9 Finland
Certain congenital musculoskeletal deformities, Varus deformities of feet[TALIPES VARUS CONGENITUS]
+∞
9.4
9
*
M01AH05
ATC
etoricoxib; oral
1.6
9.4
427
3314
L28
ICPC
Limited function/disability (L)
2.2
9.4
98
474
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
2.6
9.1
64
254
M17.1
ICD-10 Finland
Other primary gonarthrosis
2.1
9.0
111
579
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.3
9.0
84
388
NHK68
NOMESCO Finland
Shortening or lengthening osteotomy of ankle or foot
18.8
8.9
13
7
ZZH21
NOMESCO Finland
Graft of patients own bone, small pieces
4.9
8.9
28
59
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.3
8.9
79
357
M01AC06
ATC
meloxicam; systemic, rectal
1.7
8.8
235
1586
M76.7
ICD-10 Finland
Peroneal tendinitis
8.7
8.8
18
21
NH2AA
NOMESCO Finland
Heel X-ray examination
10.8
8.8
16
15
AA1AD
NOMESCO Finland
CT of head and brain
1.9
8.7
138
791
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
8.6
293
2104
TNX32
NOMESCO Finland
Custom moulded splint, unspecified region
2.8
8.6
54
200
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.7
8.6
182
1148
WX213
NOMESCO Finland
Lower leg blockade
10.2
8.5
16
16
NFK30
NOMESCO Finland
Angulation, rotation or displacement osteotomy of femur
20.2
8.5
12
6
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
4.8
8.5
27
58
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.0
8.5
103
535
Q65.0
ICD-10 Finland
Congenital dislocation of hip, unilateral
+∞
8.3
8
*
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
5.6
8.3
23
42
M01AE03
ATC
ketoprofen; systemic, rectal
1.6
8.3
235
1611
S93.4
ICD-10 Finland
Sprain and strain of ankle
1.9
8.2
120
667
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
8.2
186
1198
ZXA10
NOMESCO Finland
Bilateral
1.9
8.1
132
763
9344
FHL
Other operation on soft tissue of the foot
33.7
8.1
10
*
M02AA07
ATC
piroxicam; topical
1.6
8.0
215
1448
NHG76
NOMESCO Finland
Arthroplasty of other tarsometatarsal joint
6.4
8.0
20
32
NHG70
NOMESCO Finland
Arthroplasty of first tarsometatarsal joint
6.2
7.9
20
33
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.5
7.8
58
239
UJF32
NOMESCO Finland
Coloscopy
1.7
7.8
157
972
R4180
NOMESCO Finland
Podiatric therapy
7.0
7.8
18
26
NHH99
NOMESCO Finland
Other operation on joint of ankle or foot, unspecified
45.4
7.7
9
*
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
4.0
7.6
29
75
NH1CM
NOMESCO Finland
Ankle and foot extensive MRI examination with 3 Tesla magnet
25.2
7.6
10
*
M03BX02
ATC
tizanidine; oral
1.5
7.5
450
3641
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.3
7.5
65
291
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.5
7.4
55
226
9345
FHL
Tendon or tendon transplantation
80.7
7.4
8
*
NGU10
NOMESCO Finland
Removal of external fixation device from knee or lower leg
80.7
7.4
8
*
NHU10
NOMESCO Finland
Removal of external fixation device from ankle or foot
8.5
7.3
15
18
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.6
7.3
194
1298
N06AX21
ATC
duloxetine; oral
2.0
7.3
88
454
M03BC01
ATC
orphenadrine (citrate); systemic
1.7
7.3
181
1191
Q65.1
ICD-10 Finland
Congenital dislocation of hip, bilateral
+∞
7.3
7
*
J01DB01
ATC
cefalexin; oral
1.6
7.2
670
5939
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.2
7.2
74
358
SPAT1210
SPAT
Application of cast or individual aid
2.9
7.2
42
151
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.7
7.1
154
972
L04AA01
ATC
[U] ciclosporin; systemic
5.4
7.1
20
38
A02BC01
ATC
omeprazole; systemic
1.7
7.1
174
1139
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.7
7.0
145
906
M01AH01
ATC
celecoxib; oral (coxibs)
1.9
6.9
108
616
A02BC05
ATC
esomeprazole; systemic
1.5
6.9
258
1880
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.8
6.7
127
770
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.5
6.7
361
2834
R03AC02
ATC
salbutamol; inhalant
1.5
6.7
421
3415
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.8
6.7
106
607
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
4.3
6.6
23
55
SPAT1216
SPAT
Assessment of functional ability
2.0
6.6
87
465
M22.0
ICD-10 Finland
Recurrent dislocation of patella
4.8
6.6
20
42
J01AA02
ATC
doxycycline; systemic
1.5
6.6
534
4547
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
1.9
6.5
96
537
XKC03
NOMESCO Finland
Water cystometry
3.7
6.5
26
71
NHM20
NOMESCO Finland
Excision of synovial ganglion of ankle or foot
6.2
6.5
16
26
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.7
6.4
143
908
NH1BM
NOMESCO Finland
Ankle and foot MRI examination with 3 Tesla magnet
70.3
6.4
7
*
A03FA02
ATC
cisapride; oral, rectal
2.4
6.4
51
217
SPAT1301
SPAT
No procedures
1.5
6.4
243
1771
TNX39
NOMESCO Finland
Other orthopedic bandage, unspecified region
5.0
6.4
19
39
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.6
6.4
169
1128
M70.6
ICD-10 Finland
Trochanteric bursitis
2.0
6.3
73
372
G04BD07
ATC
tolterodine; oral
3.3
6.3
29
89
NF1BA
NOMESCO Finland
Hip extensive X-ray examination
4.6
6.3
20
44
NK4EA
NOMESCO Finland
Joint X-ray examintion with load or wrench not elsewhere classified
11.1
6.3
11
10
R52.9
ICD-10 Finland
Pain, unspecified
2.1
6.3
68
337
M21.0
ICD-10 Finland
Valgus deformity, not elsewhere classified
18.2
6.3
9
5
M21.1
ICD-10 Finland
Varus deformity, not elsewhere classified
18.2
6.3
9
5
M66.4
ICD-10 Finland
Spontaneous rupture of other tendons
18.2
6.3
9
5
Q74.3
ICD-10 Finland
Arthrogryposis multiplex congenita
+∞
6.3
6
*
L89
ICD-10 Finland
Decubitus ulcer and pressure area
7.1
6.2
14
20
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
4.2
6.2
22
54
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.4
6.2
51
224
M67.0
ICD-10 Finland
Short Achilles tendon (acquired)
6.3
6.2
15
24
ZA7.0
ICD-10 Finland
Ankle and foot
5.8
6.2
16
28
J01DA01
ATC
[U] cefalexin; systemic
1.4
6.2
475
3979
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
3.3
6.2
29
91
H02AB04
ATC
methylprednisolone; systemic
1.8
6.2
95
541
M01AB05
ATC
diclofenac; systemic, rectal
1.4
6.0
456
3797
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
2.7
6.0
37
139

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
109
504
2.31
13.65
4.3
3.2
—
—
—
0
0
270
1723
1.78
13.61
4.3
3.1
—
—
—
0
0
379
2720
1.64
12.12
4.8
4.8
36.7
36.9
g/l
0.28
361
2543
393
2899
1.60
10.94
6.0
6.1
1.2
1.2
mmol/l
1.12
368
2642
154
886
1.88
10.66
2.2
1.6
—
—
—
0
0
165
973
1.84
10.55
2.3
2.0
—
—
—
0
0
247
1637
1.68
10.50
3.2
2.6
1936.4
4652.9
umol/l
0.82
225
1467
254
1704
1.66
10.28
4.2
3.3
1.0
1.0
kg/l
0.73
28
223
112
586
2.03
10.22
21.8
15.3
1.0
1.2
inr
2.06
15
90
183
1130
1.76
10.01
3.2
2.7
1.6
0.9
e6/l
0.99
112
599
235
1560
1.67
9.86
4.8
4.0
—
—
—
0
0
584
4784
1.55
9.84
3.6
3.1
—
—
—
0
0
512
4085
1.53
9.67
4.5
4.6
6.4
6.4
mmol/l
0.39
487
3731
417
3212
1.52
9.10
7.1
6.6
1.2
1.2
mmol/l
0.36
366
2737
268
1871
1.60
9.08
3.9
3.5
7.4
7.4
ph
3.13
54
341
271
1900
1.59
9.01
3.9
2.9
0.5
0.4
e6/l
0.21
212
1385
264
1840
1.60
9.00
2.5
2.1
233.3
265.4
u/l
0.19
245
1740
446
3491
1.51
8.98
4.2
3.9
—
—
—
0
0
282
1999
1.58
8.93
5.1
3.4
0.0
0.0
estimate
1.28
85
732
496
3984
1.50
8.72
6.2
6.1
0.0
0.0
e9/l
1.02
445
3462
510
4122
1.50
8.69
6.3
6.5
0.2
0.2
e9/l
1.38
462
3648
494
3973
1.49
8.58
6.3
6.1
0.5
0.6
e9/l
0.51
443
3453
210
1402
1.63
8.48
3.0
2.5
5.7
7.4
e6/l
1.07
181
1236
877
8053
1.88
8.19
15.4
11.0
20.6
20.9
mg/l
0.11
724
6061
266
1896
1.55
8.11
3.4
2.9
—
—
—
0
0
274
1967
1.55
8.08
3.1
2.5
—
—
—
0
0
549
4544
1.48
8.05
8.9
8.8
3.9
3.9
e9/l
0.00
488
3956
650
5590
1.49
7.66
4.5
3.8
9.7
9.7
mm/h
0.05
623
5193
505
4141
1.45
7.58
6.3
6.1
2.0
2.0
e9/l
0.15
458
3680
312
2331
1.50
7.55
6.8
6.4
1.1
1.1
inr
0.31
94
750
848
7763
1.70
7.30
15.3
11.6
139.8
139.6
mmol/l
1.48
834
7553
292
2165
1.50
7.29
2.9
2.5
53.3
55.8
u/l
0.72
275
2004
470
3821
1.44
7.28
4.6
3.1
0.0
0.0
estimate
0.00
84
733
85
459
1.93
7.09
4.7
4.4
74.8
70.8
ng/l
0.12
78
418
474
3872
1.44
7.09
4.6
3.1
0.0
0.0
estimate
0.80
86
724
301
2260
1.48
7.01
3.3
3.0
45.3
31.6
ng/l
0.36
185
1236
267
1960
1.50
6.94
7.0
6.8
—
—
—
0
0
195
1339
1.57
6.89
1.3
1.2
13.6
28.0
iu/ml
5.28
65
406
281
2091
1.48
6.81
3.9
3.0
20.5
99.3
e6/l
1.55
222
1571
289
2168
1.47
6.71
3.0
3.0
2.3
2.4
mmol/l
1.86
270
1956
847
7791
1.66
6.66
15.4
11.7
3.9
3.9
mmol/l
0.27
833
7554
64
321
2.06
6.57
4.2
5.8
—
—
—
0
0
104
614
1.78
6.55
6.0
8.2
5.0
5.2
kpa
1.06
99
589
166
1113
1.59
6.47
1.4
1.4
451.7
517.3
titre
0.17
24
208
466
3836
1.41
6.46
5.9
4.3
0.0
0.0
estimate
0.50
87
752
103
611
1.77
6.39
5.9
8.3
1.3
0.9
mmol/l
0.42
83
497
61
304
2.07
6.38
1.8
2.0
—
—
—
0
0
228
1654
1.49
6.20
2.1
1.9
1.5
0.9
mg/l
0.51
170
1212
433
3540
1.40
6.15
5.6
5.8
10.3
10.8
umol/l
0.42
409
3335
185
1293
1.53
5.99
1.3
1.2
1.4
10.5
u/ml
4.62
72
493
33
133
2.53
5.66
1.8
1.7
8474.8
13376.7
e6/l
0.45
24
95
314
2475
1.40
5.35
1.8
1.7
97.9
96.4
pmol/l
0.20
161
1295
323
2570
1.38
5.17
4.4
3.4
40.7
81.2
e6/l
1.05
241
1700
621
5487
1.36
5.01
7.6
6.7
80.0
78.7
u/l
0.32
601
5163
799
7368
1.47
4.99
18.4
13.8
333.8
333.8
g/l
0.06
794
7321
41
195
2.15
4.89
5.4
4.5
—
—
—
0
0
124
839
1.55
4.62
1.4
1.4
—
—
—
0
0
687
6226
1.35
4.33
4.3
3.8
14.6
14.5
pmol/l
0.54
641
5723
56
312
1.84
4.32
5.9
10.4
—
—
—
0
0
146
1043
1.47
4.20
2.0
2.6
2.4
2.4
mmol/l
0.96
133
910
11
27
4.11
4.17
1.8
1.7
—
—
—
0
0
137
978
1.47
3.96
2.3
2.4
30.1
29.6
s
0.50
132
951
24
100
2.44
3.91
1.3
1.5
—
—
—
0
0
890
8480
1.56
3.83
13.4
10.0
—
—
—
0
0
240
1899
1.35
3.82
4.8
4.2
—
—
—
0
0
588
5258
1.30
3.80
4.9
3.8
—
—
—
0
0
18
66
2.76
3.77
1.1
1.0
—
—
—
0
0
156
1153
1.42
3.74
2.8
3.2
313.8
705.1
ng/l
1.12
103
726
259
2081
1.33
3.70
4.4
3.2
8.3
8.3
mmol/l
0.02
237
1795
81
526
1.59
3.63
2.4
3.3
4.7
4.7
pmol/l
0.14
76
469
137
996
1.44
3.60
3.0
2.3
13.8
14.5
umol/l
0.54
130
918
179
1369
1.38
3.51
1.5
1.4
21.1
20.6
nmol/l
0.15
170
1178
166
1255
1.39
3.49
1.5
1.6
449.3
28874969.7
pmol/l
1.52
150
1084
74
478
1.59
3.41
1.3
1.4
—
—
—
0
0
64
399
1.65
3.39
2.2
2.4
13.0
7.7
ug/l
0.37
58
361
706
6511
1.30
3.39
5.5
4.6
38.3
38.4
mmol/mol
0.13
674
6153
204
1605
1.34
3.34
3.4
3.3
623.7
272.3
mg/l
0.40
136
1067
211
1678
1.33
3.20
4.0
4.1
7.6
10.7
mg/mmol
0.56
148
1092
275
2272
1.29
3.16
2.3
2.2
—
—
—
0
0
144
1083
1.39
3.13
3.5
2.8
3.5
2.8
e6/l
0.35
78
557
759
7095
1.31
3.13
16.6
13.6
13.4
13.4
%
0.56
751
6966
418
3642
1.26
3.09
6.1
6.3
0.7
0.7
%
0.10
398
3430
52
317
1.68
3.03
2.3
1.7
—
—
—
0
0
434
3805
1.25
3.02
6.3
6.4
8.2
8.3
%
0.40
412
3601
777
7298
1.32
3.01
5.1
4.5
1.8
2.1
mu/l
0.76
746
6817
86
594
1.49
2.96
3.2
2.2
10.9
13.0
nmol/l
1.79
73
545
943
9176
1.82
2.95
21.7
16.0
257.3
258.1
e9/l
0.14
929
8960
761
7134
1.30
2.95
4.2
3.6
5.8
5.7
mmol/l
0.29
729
6631
449
3961
1.25
2.93
6.0
6.2
29.4
30.0
%
0.56
425
3750
88
613
1.48
2.91
1.5
1.3
214.9
225.2
u/ml
0.04
80
569
170
1328
1.34
2.90
3.7
2.5
557.7
570.0
mosm/kgh2o
0.24
150
1150
430
3779
1.25
2.90
6.1
6.2
2.9
2.8
%
0.27
409
3550
20
89
2.27
2.88
2.2
4.0
—
—
—
0
0
114
836
1.41
2.87
3.2
2.3
22.7
24.4
%
0.65
96
732
943
9184
1.79
2.82
21.6
15.9
30.1
30.0
pg
0.22
938
9089
943
9184
1.79
2.82
21.6
15.9
89.9
89.8
fl
0.30
938
9090
123
917
1.39
2.82
3.0
2.2
2.4
2.4
g/l
0.26
115
846
943
9185
1.79
2.81
21.7
16.0
4.6
4.6
e12/l
0.15
927
8955
24
117
2.08
2.79
2.3
3.5
1.2
2.5
ratio
—
6
12
127
954
1.38
2.79
1.5
1.6
1340.5
1175.6
nmol/l
0.97
96
733
58
373
1.59
2.76
1.6
1.6
9.0
8.2
u/l
0.15
46
296
943
9189
1.78
2.74
21.7
16.0
6.8
6.6
e9/l
0.95
929
8954
442
3916
1.24
2.71
6.1
6.0
56.3
55.7
%
0.54
421
3710
943
9191
1.77
2.71
21.8
16.1
137.2
136.9
g/l
0.27
938
9093
11
37
3.00
2.70
1.3
1.5
36.8
34.7
%
—
6
26
100
727
1.42
2.66
6.9
6.9
104.9
104.2
mmol/l
0.74
100
710
410
3609
1.23
2.66
9.8
8.5
0.0
0.0
e9/l
0.29
347
2916
29
157
1.87
2.54
5.3
3.7
3.8
3.8
mmol/l
0.06
29
144
35
203
1.75
2.47
2.6
3.0
—
—
—
0
0
215
1772
1.27
2.47
2.4
2.2
2.9
2.8
mg/l
0.20
185
1522
20
97
2.08
2.38
1.5
1.6
—
—
—
0
0
43
268
1.63
2.36
4.7
6.3
9.7
9.2
kpa
1.09
43
248
9
28
3.23
2.31
5.3
2.1
160.2
109.9
ug/l
—
9
28
20
99
2.04
2.27
1.6
1.7
—
—
—
0
0
22
113
1.97
2.26
3.6
2.4
17.0
16.4
%
0.34
13
54
875
8439
1.36
2.23
10.7
8.7
28.0
27.2
u/l
0.45
856
8175
18
349
0.51
2.22
1.9
1.5
—
—
—
0
0
86
632
1.40
2.18
2.6
2.8
11.4
10.2
g/l
1.44
80
574
20
101
2.00
2.16
3.3
3.2
—
—
—
0
0
59
406
1.48
2.13
1.1
1.1
—
—
—
0
0
81
592
1.40
2.13
7.4
8.8
—
—
—
0
0
18
343
0.52
2.12
1.8
1.4
—
—
—
0
0
10
37
2.72
2.10
2.3
1.5
—
25.1
—
0
6
47
309
1.55
2.09
2.3
3.3
20.6
21.5
s
0.96
38
278
69
492
1.43
2.08
3.7
5.3
7.4
7.4
ph
—
10
44
108
831
1.34
2.07
2.9
3.3
4.6
7.2
umol/l
3.04
92
701
18
340
0.52
2.06
1.8
1.4
—
—
—
0
0
32
192
1.69
2.05
1.3
1.5
256.5
303.6
ug/g
0.61
17
115
6
15
4.02
2.04
1.5
1.3
—
—
—
0
0
301
2637
1.20
1.93
5.9
6.2
—
—
—
0
0
10
39
2.58
1.92
1.3
2.4
—
—
—
0
0
61
433
1.44
1.90
4.9
6.3
24.1
24.0
mmol/l
0.18
53
409
67
484
1.41
1.90
1.2
1.2
—
—
—
0
0
74
544
1.39
1.90
6.5
7.8
1.3
1.3
mmol/l
0.09
68
521
261
2987
0.83
1.87
2.2
2.4
—
—
—
0
0
45
302
1.51
1.86
7.8
9.8
23.9
24.3
mmol/l
0.29
39
288
17
87
1.97
1.80
1.7
1.5
—
—
—
0
0
8
29
2.77
1.79
1.5
1.3
—
—
—
0
0
746
7106
1.21
1.78
3.8
3.3
1.3
1.3
mmol/l
0.48
719
6691
45
305
1.50
1.78
2.2
2.2
—
—
—
0
0
65
475
1.39
1.75
4.7
3.4
1.2
1.2
mmol/l
1.81
60
409
777
7438
1.22
1.73
4.3
3.7
4.6
4.7
mmol/l
1.18
749
7043
27
163
1.68
1.73
3.0
1.9
—
—
—
0
0
65
478
1.39
1.69
1.5
1.2
—
—
—
0
0
783
7509
1.22
1.66
4.7
4.0
2.8
2.8
mmol/l
0.35
752
7056
420
3827
1.17
1.66
3.2
2.8
88.7
95.6
ug/l
0.26
401
3579
6
19
3.17
1.66
4.7
3.3
—
—
—
0
0
160
1336
1.24
1.64
3.7
3.9
2.8
1.9
ug/l
0.30
149
1221
21
120
1.77
1.63
1.5
1.4
—
—
—
0
0
96
755
1.30
1.62
2.5
2.0
333.1
370.3
nmol/l
1.12
89
699
61
448
1.39
1.61
2.5
2.3
—
—
—
0
0
38
255
1.51
1.60
1.2
1.2
—
—
—
0
0
23
137
1.70
1.56
6.1
2.7
8.9
9.0
kpa
0.12
23
137
46
323
1.45
1.56
4.5
2.5
0.2
0.1
e6/l
0.50
40
310
201
1728
1.21
1.55
2.4
2.1
—
—
—
0
0
12
57
2.12
1.55
1.3
1.3
1.4
1.3
nmol/l
0.18
12
51
79
609
1.32
1.54
3.2
2.4
8584.3
3310.3
u/l
0.71
28
255
16
86
1.87
1.51
1.3
1.3
853.3
341.0
pmol/l
1.39
11
66
5
129
0.38
1.49
1.0
1.0
—
—
—
0
0
29
187
1.57
1.47
1.7
2.0
129.8
179.1
e6/l
0.18
24
144
29
187
1.57
1.47
1.7
1.9
3.0
10.2
e6/l
0.90
22
140
15
80
1.89
1.45
1.0
1.3
—
—
—
0
0
260
2303
1.18
1.43
1.3
1.4
0.7
1.8
u/ml
2.90
79
582
170
1976
0.83
1.41
1.7
1.7
—
—
—
0
0
83
655
1.29
1.39
4.7
5.4
1.8
1.7
mmol/l
0.09
68
518
59
446
1.34
1.34
2.6
3.4
83.1
72.6
e9/l
0.56
49
326
68
526
1.31
1.32
1.6
1.5
18.7
22.7
iu/l
0.54
59
429
6
24
2.51
1.30
3.2
5.0
—
—
—
0
0
9
43
2.10
1.30
1.7
3.2
29.7
28.9
umol/l
—
9
43
22
137
1.62
1.30
6.2
2.7
5.3
4.9
kpa
2.04
22
137
22
137
1.62
1.30
6.2
2.7
2.2
2.5
mmol/l
0.24
17
82
104
853
1.25
1.28
1.2
1.2
—
—
—
0
0
15
84
1.80
1.27
1.8
1.3
—
—
—
0
0
16
92
1.75
1.25
1.8
1.5
—
—
—
0
0
81
649
1.27
1.23
2.4
3.9
2.1
1.7
%
0.60
73
590
12
64
1.89
1.18
1.5
1.4
0.3
0.3
u/ml
—
5
25
311
2833
1.14
1.16
1.9
2.0
—
—
—
0
0
26
174
1.51
1.16
1.7
2.0
—
—
—
0
0
5
20
2.51
1.15
3.6
2.0
4.9
5.5
nmol/l
—
5
20
134
1560
0.84
1.14
2.0
1.8
—
—
—
0
0
7
30
2.34
1.12
1.7
1.9
—
—
—
0
0
15
88
1.72
1.11
2.6
2.1
—
—
—
0
0
13
73
1.79
1.11
1.0
1.1
0.2
2.9
u/ml
—
7
34
110
931
1.20
1.04
1.7
1.8
—
—
—
0
0
36
264
1.38
1.03
4.3
4.2
0.4
0.3
g/l
0.39
18
132
10
54
1.86
0.97
5.1
2.9
19.0
16.3
mg/l
—
10
37
86
717
1.22
0.96
1.3
1.2
73.9
159.3
iu/ml
2.25
36
286
9
52
1.74
0.92
2.0
1.1
—
—
—
0
0
49
386
1.28
0.90
4.0
5.7
—
—
—
0
0
6
29
2.08
0.89
9.7
6.6
40.2
84.6
g/mol
—
6
24
6
29
2.08
0.89
1.7
1.2
—
—
—
0
0
762
7402
1.13
0.89
4.2
3.6
1.4
1.5
mmol/l
1.35
736
6983
11
64
1.73
0.86
3.1
4.0
—
—
—
0
0
62
506
1.24
0.86
1.2
1.3
64.0
37.7
au/ml
—
5
24
23
162
1.43
0.85
2.0
2.4
—
—
—
0
0
206
1869
1.13
0.82
1.8
1.7
1.4
1.4
mmol/l
0.07
180
1624
6
32
1.88
0.82
3.2
2.0
10.2
8.9
mmol/l
—
6
25
13
81
1.61
0.81
1.1
1.2
—
296.0
—
0
5
71
846
0.83
0.81
1.4
1.5
—
—
—
0
0
39
304
1.29
0.79
5.8
2.8
—
—
—
0
0
19
131
1.46
0.78
1.1
1.1
—
—
—
0
0
22
157
1.41
0.77
1.2
1.4
—
—
—
0
0
6
34
1.77
0.76
2.3
1.4
—
—
—
0
0
19
132
1.45
0.76
1.4
1.2
3.8
5.9
u/ml
0.49
12
58
5
24
2.09
0.74
2.4
2.8
—
—
—
0
0
34
264
1.30
0.72
1.0
1.1
8.6
6.9
u/ml
0.21
17
164
29
223
1.31
0.67
7.2
7.9
—
—
—
0
0
11
70
1.58
0.65
2.1
2.1
—
—
—
0
0
25
189
1.33
0.65
1.2
1.9
3.6
3.7
mmol/l
0.04
25
177
807
7910
1.12
0.64
14.1
11.8
40.4
40.6
%
0.24
632
6420
65
760
0.84
0.64
4.9
1.9
—
—
—
0
0
19
138
1.38
0.63
7.6
2.7
—
—
—
0
0
41
335
1.23
0.60
3.4
4.5
128.2
129.8
g/l
0.18
41
329
8
51
1.57
0.60
3.6
4.3
—
—
—
0
0
32
254
1.27
0.60
1.0
1.1
0.4
1.3
u/ml
1.04
14
129
12
80
1.51
0.60
2.4
2.0
—
—
—
0
0
61
711
0.85
0.59
5.0
2.0
—
—
—
0
0
8
53
1.51
0.58
2.1
3.0
—
—
—
0
0
65
753
0.85
0.58
4.8
1.9
—
—
—
0
0
66
763
0.86
0.58
4.8
1.9
—
—
—
0
0
11
73
1.51
0.56
1.4
1.2
—
—
—
0
0
56
653
0.85
0.55
1.2
1.3
—
—
—
0
0
12
82
1.47
0.54
1.5
1.3
—
—
—
0
0
9
61
1.48
0.53
3.0
2.1
33.0
32.6
pg
—
9
61
10
66
1.52
0.52
1.1
1.2
—
—
—
0
0
66
755
0.87
0.52
4.8
2.0
—
—
—
0
0
217
2030
1.09
0.50
1.3
1.5
2.0
2.2
g/l
0.60
144
1222
85
758
1.13
0.49
1.2
1.3
—
—
—
0
0
37
308
1.21
0.48
1.6
1.6
—
—
—
0
0
14
102
1.38
0.47
1.1
1.1
1.4
1.4
g/l
0.18
14
90
65
571
1.15
0.47
4.4
4.6
1.1
1.0
%
0.09
23
156
17
129
1.32
0.46
3.1
2.7
28.5
23.6
nmol/l
0.73
17
124
136
1252
1.10
0.45
2.1
2.5
101.1
108.7
ug/g
0.17
114
980
12
86
1.40
0.44
1.1
1.1
6.8
2.6
u/ml
—
5
36
7
51
1.38
0.44
1.4
1.5
4.0
6.4
ug/l
—
7
43
13
95
1.37
0.44
1.5
1.6
—
—
—
0
0
13
95
1.37
0.44
1.5
1.6
—
—
—
0
0
13
95
1.37
0.44
1.5
1.6
—
—
—
0
0
13
95
1.37
0.44
1.5
1.6
—
—
—
0
0
40
340
1.18
0.43
1.4
1.3
—
—
—
0
0
20
158
1.27
0.42
1.6
1.4
21.8
18.9
u/l
0.16
14
139
52
593
0.87
0.41
5.7
2.1
—
—
—
0
0
33
277
1.20
0.41
1.3
1.2
—
—
—
0
0
12
161
0.74
0.41
2.6
3.6
21.0
25.1
mg/l
—
7
104
8
59
1.36
0.41
2.1
2.2
—
—
—
0
0
54
474
1.15
0.41
1.6
1.5
275.4
296.3
mu/l
0.45
47
425
11
79
1.40
0.41
2.6
2.0
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
0.7
—
0
10
16
123
1.31
0.40
1.3
1.2
—
—
—
0
0
5
34
1.47
0.40
2.6
2.9
—
—
—
0
0
12
88
1.37
0.40
1.0
1.3
—
—
—
0
0
176
1658
1.08
0.36
3.9
3.1
—
—
—
0
0
5
80
0.62
0.35
2.4
2.8
—
42.2
—
0
9
15
117
1.29
0.35
8.2
2.6
—
—
—
0
0
27
227
1.19
0.35
1.2
1.3
—
—
—
0
0
11
145
0.76
0.35
2.2
1.8
—
—
—
0
0
17
211
0.80
0.34
1.7
1.5
98.8
98.3
u/ml
—
5
37
10
73
1.37
0.34
2.0
4.0
—
—
—
0
0
18
145
1.25
0.34
1.3
1.2
—
—
—
0
0
6
46
1.31
0.33
1.5
1.5
5.2
5.9
mmol/l
—
6
46
54
486
1.12
0.30
2.7
4.3
3.6
16.2
ug/l
0.78
40
390
7
54
1.30
0.30
1.4
1.2
—
—
—
0
0
8
63
1.27
0.27
1.0
1.0
—
—
—
0
0
11
139
0.79
0.27
11.2
3.8
—
—
—
0
0
8
66
1.21
0.26
1.1
1.3
—
—
—
0
0
14
171
0.82
0.26
1.0
1.2
—
—
—
0
0
33
291
1.14
0.26
1.1
1.2
4.3
2.6
u/ml
0.26
13
135
87
811
1.08
0.26
1.3
1.4
—
—
—
0
0
9
74
1.22
0.25
1.1
1.1
—
—
—
0
0
9
75
1.20
0.25
6.6
8.7
6.2
6.8
mmol/l
—
9
59
22
255
0.86
0.24
1.2
1.4
290.2
231.0
u/ml
0.45
13
138
215
2231
0.95
0.23
4.3
2.7
—
—
—
0
0
51
557
0.91
0.23
6.1
3.7
—
—
—
0
0
59
544
1.09
0.23
4.6
4.6
0.1
0.1
%
0.41
18
143
7
93
0.75
0.22
1.1
1.5
52.9
78.2
mmol/l
—
7
83
88
827
1.07
0.22
1.1
1.2
—
—
—
0
0
18
210
0.85
0.22
1.2
1.1
—
—
—
0
0
98
925
1.07
0.22
1.3
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
1.7
—
0
11
0
10
0.00
0.21
0.0
1.3
—
18.9
—
0
10
47
512
0.91
0.21
6.2
2.6
—
—
—
0
0
50
543
0.92
0.21
1.5
1.6
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
93.5
—
0
12
0
12
0.00
0.21
0.0
1.8
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
2.0
—
0
7
0
12
0.00
0.21
0.0
2.2
—
—
—
0
0
0
14
0.00
0.20
0.0
2.1
—
1.3
—
0
14
6
50
1.20
0.19
1.5
1.1
—
—
—
0
0
6
53
1.13
0.18
1.3
1.2
—
—
—
0
0
265
2581
1.04
0.18
1.6
1.6
—
—
—
0
0
7
59
1.19
0.18
1.0
1.0
—
—
—
0
0
17
195
0.87
0.17
1.3
1.3
4.2
3.4
ug/l
0.46
17
182
20
226
0.88
0.17
1.7
1.5
—
—
—
0
0
26
288
0.90
0.17
1.1
1.2
—
—
—
0
0
8
68
1.18
0.16
1.3
1.1
—
—
—
0
0
75
790
0.95
0.16
2.8
2.6
0.5
0.7
ug/l
1.07
42
440
243
2487
0.97
0.14
2.0
2.1
—
—
—
0
0
10
84
1.19
0.14
2.0
1.8
—
—
—
0
0
56
529
1.06
0.14
4.2
4.4
0.3
0.5
%
0.58
13
112
17
151
1.13
0.13
1.0
1.0
—
—
—
0
0
11
94
1.17
0.13
1.4
1.4
—
19.2
—
0
6
23
209
1.10
0.13
2.4
2.9
6.7
7.0
umol/l
0.04
15
157
10
117
0.85
0.13
1.5
1.6
—
—
—
0
0
11
127
0.86
0.12
3.0
2.4
—
—
—
0
0
19
210
0.90
0.12
1.2
1.1
—
—
—
0
0
55
522
1.06
0.12
4.8
4.7
0.1
0.1
%
0.05
14
121
14
158
0.88
0.12
3.0
3.6
59.6
55.6
%
0.70
14
158
15
133
1.13
0.12
3.1
6.1
—
—
—
0
0
110
1135
0.97
0.11
1.2
1.3
—
—
—
0
0
39
368
1.06
0.10
1.0
1.1
—
—
—
0
0
20
183
1.09
0.10
1.0
1.1
8.7
7.0
u/ml
0.11
11
82
5
44
1.14
0.10
1.6
1.5
—
—
—
0
0
15
166
0.90
0.10
1.1
1.1
—
—
—
0
0
5
46
1.09
0.09
1.0
1.1
1279.6
1623.9
miu/ml
—
5
46
5
46
1.09
0.09
2.0
1.3
—
—
—
0
0
5
48
1.04
0.09
1.0
1.3
—
—
—
0
0
14
155
0.90
0.09
2.8
3.4
4.4
4.0
e9/l
0.43
14
155
6
55
1.09
0.09
1.8
1.6
0.8
1.0
g/l
—
6
55
71
686
1.04
0.08
5.5
3.3
—
—
—
0
0
6
57
1.05
0.08
2.3
2.4
84.8
17.0
ug/l
—
6
57
55
572
0.96
0.08
1.1
1.2
—
143.1
—
0
13
31
328
0.94
0.08
8.8
2.6
—
—
—
0
0
7
65
1.08
0.08
1.4
1.4
—
—
—
0
0
15
137
1.10
0.07
1.1
1.1
3.5
148.2
iu/ml
—
6
43
133
1303
1.02
0.07
1.6
1.6
—
—
—
0
0
14
153
0.91
0.07
1.1
1.2
—
—
—
0
0
46
474
0.97
0.04
1.3
1.4
—
—
—
0
0
140
1414
0.99
0.03
1.6
1.5
—
—
—
0
0
11
118
0.93
0.02
1.5
1.2
—
—
—
0
0
21
203
1.04
0.01
1.0
1.0
4.1
6.5
u/ml
0.56
11
83
52
527
0.99
0.01
1.2
1.4
—
—
—
0
0
14
136
1.03
0.00
6.8
5.9
412.2
390.1
umol/l
0.22
14
127
15
146
1.03
0.00
1.1
1.1
—
—
—
0
0
10
98
1.02
0.00
1.1
2.6
—
—
—
0
0
21
207
1.01
0.00
1.2
1.4
80.3
146.9
pmol/l
0.57
21
202
44
443
0.99
0.00
1.3
1.3
174.7
245.8
miu/ml
1.11
21
224
24
245
0.98
0.00
1.3
1.3
—
—
—
0
0
26
255
1.02
0.00
1.0
1.1
6.2
3.5
u/ml
—
8
71
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
6
64
0.94
0.00
1.2
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
2.7
—
—
—
0
0
8
86
0.93
0.00
2.1
1.6
—
—
—
0
0
5
54
0.93
0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
34.5
—
0
6
5
57
0.88
0.00
3.6
10.3
11.5
12.0
%
—
5
57
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
2.1
—
188.6
—
0
7
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
6
61
0.98
0.00
1.0
1.0
—
—
—
0
0
6
68
0.88
0.00
1.8
3.0
—
—
—
0
0
0
5
0.00
0.00
0.0
7.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint Q17_CONGEN_DEFORMITI_FEET and mortality.

Females

Parameter HR [95% CI] p-value
Q17_CONGEN_DEFORMITI_FEET 1.245 [1.01, 1.53] 0.039
Birth year 0.997 [0.99, 1.01] 0.516

During the follow-up period (1.1.1998 — 31.12.2019), 139 out of 5121 females with Q17_CONGEN_DEFORMITI_FEET died.

Males

Parameter HR [95% CI] p-value
Q17_CONGEN_DEFORMITI_FEET 1.2 [0.98, 1.48] 0.085
Birth year 0.987 [0.98, 1.0] 0.006

During the follow-up period (1.1.1998 — 31.12.2019), 158 out of 5999 males with Q17_CONGEN_DEFORMITI_FEET died.

Mortality risk

Mortality risk for people of age

years, who have Q17_CONGEN_DEFORMITI_FEET.

N-year risk Females Males
1 0.132% 0.187%
5 0.679% 1.352%
10 1.731% 3.274%
15 3.539% 6.665%
20 6.656% 10.99%

Relationships between endpoints

Index endpoint: Q17_CONGEN_DEFORMITI_FEET – Congenital deformities of feet

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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