Congenital deformities of feet

Q17_CONGEN_DEFORMITI_FEET

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 Q66
  • Cause of death: ICD-10 Q66

2 out of 7 registries used, show all original rules.

1021

4. Check minimum number of events

None

1021

5. Include endpoints

None

1021

6. Filter based on genotype QC (FinnGen only)

979

Control definitions (FinnGen only)

Control exclude
Q17_CONGEN_MALFO_DEFORMAT_MUSCULOS_SYSTEM

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
Q6[5-9]|Q7
Name in latin
Deformitates congenitae pedum

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 12688 5897 6770
Only index persons 10876 5130 5746
Unadjusted period prevalence (%)
Whole population 0.18 0.17 0.19
Only index persons 0.20 0.19 0.22
Median age at first event (years)
Whole population 10.23 12.31 8.35
Only index persons 12.68 14.50 11.06

-FinnGen-

Key figures

All Female Male
Number of individuals 979 612 367
Unadjusted period prevalence (%) 0.20 0.22 0.17
Median age at first event (years) 38.30 39.63 36.09

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1021
Matched controls
10210
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q66.7
ICD-10 Finland
Pes cavus
1189.7
307.7
326
*
Q66.0
ICD-10 Finland
Talipes equinovarus
+∞
247.2
227
*
Q66.5
ICD-10 Finland
Congenital pes planus
278.2
184.2
183
8
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
7.0
137.5
248
450
NHK40
NOMESCO Finland
Osteotomy or rotation osteotomy of II-V metatarsal or tarsal bone
19.8
134.7
107
60
Q66.8
ICD-10 Finland
Other congenital deformities of feet
1408.4
130.2
124
*
NHL68
NOMESCO Finland
Tenodesis, shortening or lengthening of tendon of foot
22.2
106.7
80
39
NHL14
NOMESCO Finland
Shortening or lengthening of achilles tendon
44.7
105.6
63
15
NHU20
NOMESCO Finland
Removal of internal fixation device from ankle or foot
9.5
95.0
119
140
Q66.9
ICD-10 Finland
Congenital deformity of feet, unspecified
465.9
87.5
86
*
NHG22
NOMESCO Finland
Fusion of subtalar joint
33.5
83.8
54
17
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
6.9
83.3
140
231
M21.4
ICD-10 Finland
Flat foot [pes planus] (acquired)
9.2
79.8
101
120
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
5.5
78.0
167
348
Q66.2
ICD-10 Finland
Metatarsus varus
412.7
77.9
77
*
NHK30
NOMESCO Finland
Osteotomy or rotation osteotomy of first metatarsal or tarsal bone
7.9
65.4
94
130
NHL99
NOMESCO Finland
Other operation on muscle or tendon of ankle or foot
23.5
61.9
45
20
NHK99
NOMESCO Finland
Other operation on bone of ankle or foot
10.9
56.6
62
60
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
7.3
55.8
85
125
TNX92
NOMESCO Finland
Supporting bandage or orthosis of lower limb
10.9
55.7
61
59
M20.4
ICD-10 Finland
Other hammer toe(s) (acquired)
7.6
54.9
81
115
NH3FA
NOMESCO Finland
Weight-bearing X-ray of foot
9.8
52.3
62
67
Q66.4
ICD-10 Finland
Talipes calcaneovalgus
+∞
51.5
49
*
NH1AD
NOMESCO Finland
Ankle and foot CT
8.9
51.2
65
77
M20.1
ICD-10 Finland
Hallux valgus (acquired)
4.5
48.2
130
324
M19.2
ICD-10 Finland
Other secondary arthrosis
13.8
47.9
45
34
NH1BG
NOMESCO Finland
Ankle and foot MRI examination with high intensity magnet
8.5
47.8
63
78
7545B
ICD-9 Finland
Certain congenital musculoskeletal deformities, Varus deformities of feet[TALIPES EQUINOVARUS CONGENITUS]
489.7
47.7
47
*
Q66.6
ICD-10 Finland
Other congenital valgus deformities of feet
+∞
47.3
45
*
TNH33
NOMESCO Finland
Custom moulded brace, ankle or foot
11.7
46.1
48
43
NH1FA
NOMESCO Finland
Weight-bearing X-ray of ankle
15.6
44.4
39
26
75400
ICD-8 Finland
Clubfoot (congenital), Pes equino-varus adductus
+∞
44.1
42
*
TNX50
NOMESCO Finland
Removal of cutom molded cast and internal stretch
4.7
38.7
95
219
NH1CG
NOMESCO Finland
Ankle and foot extensive MRI examination with high intensity magnet
9.2
38.3
47
53
SPAT1229
SPAT
Assessment of need for aid
4.9
38.3
88
192
L84
ICD-10 Finland
Corns and callosities
6.2
38.2
67
114
M21.5
ICD-10 Finland
Acquired clawhand, clubhand, clawfoot and clubfoot
83.3
36.1
40
5
L17
ICPC
Foot/toe symptom/complaint
2.4
35.9
363
1919
M19.0
ICD-10 Finland
Primary arthrosis of other joints
3.5
34.6
128
397
NHG24
NOMESCO Finland
Fusion of subtalar joint and between bones of ankle
47.3
34.0
41
9
L16
ICPC
Ankle symptom/complaint
2.8
32.9
196
802
TQW40
NOMESCO Finland
Remowal of suture of skin
3.8
32.5
106
302
TNH31
NOMESCO Finland
Prefabricated orthosis, ankle or foot
9.8
31.7
37
39
B01AB05
ATC
enoxaparin; parenteral
2.4
31.6
301
1537
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.9
31.2
169
656
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
4.7
31.1
75
170
NHG26
NOMESCO Finland
Fusion between bones of ankle or ankle and foot
9.6
31.1
37
40
9341
FHL
Reduction and plaster or plaster exchange
165.0
30.8
32
*
TNH36
NOMESCO Finland
Custom molded cast of pes equinovarus
+∞
30.4
29
*
Q66.3
ICD-10 Finland
Other congenital varus deformities of feet
+∞
30.4
29
*
NH3EA
NOMESCO Finland
Feet X-ray examination with load
6.9
30.0
47
71
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
4.2
29.9
83
210
M79.6
ICD-10 Finland
Pain in limb
2.1
29.3
456
2820
ZXA00
NOMESCO Finland
Right side
2.4
29.1
257
1264
NHG80
NOMESCO Finland
Fusion of first tarsometatarsal joint
5.5
27.1
53
100
NHG77
NOMESCO Finland
Arthroplasty of interphalangeal tarsal joint(s)
8.0
26.9
37
48
ZXA05
NOMESCO Finland
Left side
2.3
25.9
235
1163
-, ,
ICD-10 Finland
7.3
25.1
37
52
9343
FHL
Posterior release or posteromedical release
256.1
24.8
25
*
ZXE10
NOMESCO Finland
More than one and less than three hours
2.0
24.7
364
2173
NH1EA
NOMESCO Finland
Ankle X-ray examination with load or wrench
31.9
23.8
31
10
NHK10
NOMESCO Finland
Incision or excision of metatarsal or tarsal bone
9.6
23.6
28
30
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.1
22.6
281
1568
N02AX02
ATC
tramadol; systemic, rectal
2.0
22.4
388
2435
M77.4
ICD-10 Finland
Metatarsalgia
3.1
21.4
96
333
N02AJ06
ATC
codeine and paracetamol; systemic
1.9
21.4
440
2912
M25.5
ICD-10 Finland
Pain in joint
1.9
21.4
361
2239
TNX34
NOMESCO Finland
Major custom molded cast, unspecified region
7.1
21.3
32
46
WX320
NOMESCO Finland
Spinalanesthesy
2.1
21.2
231
1223
NHL20
NOMESCO Finland
Myotomy or tenotomy of foot
28.7
21.0
28
10
NHT62
NOMESCO Finland
Surgical procedure for correction of pes equinovarus
+∞
20.9
20
*
M19.1
ICD-10 Finland
Post-traumatic arthrosis of other joints
5.2
20.9
43
85
G60.0
ICD-10 Finland
Hereditary motor and sensory neuropathy
49.1
20.2
24
5
R4110
NOMESCO Finland
Physiotherapy
2.0
20.0
282
1637
Z31.5
ICD-10 Finland
Genetic counselling
3.0
20.0
94
335
NHG20
NOMESCO Finland
Fusion of talocrural joint
36.6
19.9
25
7
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
3.8
19.8
62
171
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.6
19.4
122
507
ZZH21
NOMESCO Finland
Graft of patients own bone, small pieces
6.6
19.3
31
48
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
2.6
19.2
126
534
N03AX12
ATC
[U] gabapentin; oral
2.3
19.1
163
778
N03AX16
ATC
[U] pregabalin
2.1
19.0
218
1172
SPAT1225
SPAT
Implementation of podiatry rehabilitation plan
5.5
18.6
36
67
NHE15
NOMESCO Finland
Suture or reinsertion of ligament of ankle
8.0
18.3
25
32
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
3.1
18.1
78
264
L28
ICPC
Limited function/disability (L)
2.3
18.0
144
667
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.8
18.0
417
2823
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.6
17.9
109
445
Q66.1
ICD-10 Finland
Talipes calcaneovarus
67.8
17.8
20
*
Z50.1
ICD-10 Finland
Other physical therapy
3.5
17.5
62
186
L82
ICPC
Congenital anomaly musculoskeletal
172.7
16.5
17
*
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
5.1
16.3
34
68
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.3
15.9
124
568
TNX32
NOMESCO Finland
Custom moulded splint, unspecified region
3.0
14.9
66
227
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.4
14.7
105
462
M20.5
ICD-10 Finland
Other deformities of toe(s) (acquired)
14.4
14.6
24
17
S18
ICPC
Laceration/cut
1.7
14.6
415
2933
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.9
14.4
69
248
N02BE01
ATC
paracetamol; systemic, rectal
2.0
14.4
856
7391
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
4.4
14.1
35
81
M21.6
ICD-10 Finland
Other acquired deformities of ankle and foot
14.7
14.1
23
16
ZXE20
NOMESCO Finland
More than three and less than five hours
2.2
14.0
129
633
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
2.7
13.8
79
313
A46
ICD-10 Finland
Erysipelas
2.3
13.7
116
550
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.9
13.6
66
239
9111
FHL
Plastering under anesthesia
26.1
13.4
18
7
J01FF01
ATC
clindamycin; systemic
1.8
13.3
255
1605
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
4.2
13.3
35
85
Z3226
NOMESCO Finland
Physiotherapist
1.9
13.3
188
1077
NHM10
NOMESCO Finland
Fasciotomy of ankle or foot
15.3
13.1
21
14
M01AH05
ATC
etoricoxib; oral
1.6
12.8
569
4456
TNX99
NOMESCO Finland
Other orthopaedic minor procedure
3.6
12.6
41
116
Z01.8
ICD-10 Finland
Other specified special examinations
1.8
12.4
212
1286
AA1AD
NOMESCO Finland
CT of head and brain
1.8
12.3
197
1171
NHG76
NOMESCO Finland
Arthroplasty of other tarsometatarsal joint
10.7
12.3
23
22
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.9
12.3
190
1119
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
5.2
12.3
25
49
R4180
NOMESCO Finland
Podiatric therapy
6.1
12.2
21
35
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.9
12.2
59
214
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
4.3
12.1
31
74
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.5
12.0
78
328
WX213
NOMESCO Finland
Lower leg blockade
13.6
12.0
20
15
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.7
11.9
65
251
ZXD10
NOMESCO Finland
Scheduled procedure
1.6
11.9
341
2385
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
4.3
11.8
30
71
Z3229
NOMESCO Finland
Other healthcare associate professional
2.3
11.7
88
396
NHL30
NOMESCO Finland
Suture or reinsertion of tendon of foot
8.8
11.6
24
28
B01AB04
ATC
dalteparin; parenteral
3.0
11.6
50
170
NF1AA
NOMESCO Finland
Hip X-ray examination
2.7
11.5
64
250
N02BF01
ATC
gabapentin; oral
2.4
11.4
79
342
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
11.3
227
1443
N06AX21
ATC
duloxetine; oral
2.0
11.2
124
650
UJF32
NOMESCO Finland
Coloscopy
1.8
11.2
191
1156
NGA30
NOMESCO Finland
Exploration of knee joint, arthroscopic
2.8
11.1
56
208
A03FA02
ATC
cisapride; oral, rectal
2.6
11.0
64
255
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
4.6
11.0
26
58
M01AE03
ATC
ketoprofen; systemic, rectal
1.7
10.9
278
1881
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.9
10.8
143
799
NHG70
NOMESCO Finland
Arthroplasty of first tarsometatarsal joint
5.6
10.7
20
36
M76.7
ICD-10 Finland
Peroneal tendinitis
9.3
10.5
21
23
M01AC06
ATC
meloxicam; systemic, rectal
1.6
10.5
286
1963
SPAT1153
SPAT
Removal of sutures
1.7
10.5
249
1652
7545A
ICD-9 Finland
Certain congenital musculoskeletal deformities, Varus deformities of feet[TALIPES VARUS CONGENITUS]
+∞
10.4
10
*
Q65.0
ICD-10 Finland
Congenital dislocation of hip, unilateral
+∞
10.4
10
*
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.1
10.4
100
498
M01AH01
ATC
celecoxib; oral
1.9
10.4
132
727
N02BF02
ATC
pregabalin; oral
2.6
10.4
62
251
NH1AI
NOMESCO Finland
Cone beam CT of ankle
10.7
10.3
19
18
M03BX02
ATC
tizanidine; oral
1.5
10.2
568
4583
ZA7.0
ICD-10 Finland
Ankle and foot
5.1
10.1
21
42
WX212
NOMESCO Finland
Femoral plexus blockade
4.5
10.1
24
54
NH3BG
NOMESCO Finland
MRI of foot
9.2
10.0
20
22
XX9AW
NOMESCO Finland
Production of copy from X-ray picture
2.9
10.0
48
173
S83.0
ICD-10 Finland
Dislocation of patella
3.2
10.0
40
130
A02BC01
ATC
omeprazole; systemic
1.7
10.0
221
1437
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.2
10.0
83
390
S97
ICPC
Chronic ulcer skin
2.8
9.9
51
191
L04AA01
ATC
[U] ciclosporin
7.7
9.9
22
29
NHG82
NOMESCO Finland
Fusion of other tarsal joint
8.2
9.9
21
26
NHT99
NOMESCO Finland
Other operation on ankle or foot
26.3
9.8
13
5
Q87.88
ICD-10 Finland
Other specified congenital malformation syndromes, not elsewhere classified
26.3
9.8
13
5
Z3231
NOMESCO Finland
Registered nurse
1.6
9.8
261
1779
R5110, ,
SPAT
2.7
9.7
52
199
ZXA10
NOMESCO Finland
Bilateral
1.8
9.6
160
959
SPAT1210
SPAT
Application of cast or individual aid
2.7
9.6
50
189
A02BC02
ATC
pantoprazole; systemic
1.5
9.6
558
4521
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.7
9.5
198
1264
M67.0
ICD-10 Finland
Short Achilles tendon (acquired)
8.1
9.4
20
25
NGL66
NOMESCO Finland
Transposition of tendon of knee or lower leg
21.9
9.4
13
6
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
9.4
367
2730
S92.3
ICD-10 Finland
Fracture of metatarsal bone
2.7
9.3
48
180
A02BC05
ATC
esomeprazole; systemic
1.6
9.3
330
2399
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.0
9.3
105
555
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
3.6
9.3
30
85
NHK68
NOMESCO Finland
Shortening or lengthening osteotomy of ankle or foot
13.8
9.2
15
11
M02AA07
ATC
piroxicam; topical
1.6
9.2
257
1769
NHQ40
NOMESCO Finland
Amputation of toe
7.8
9.2
20
26
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.6
9.1
246
1677
R52.9
ICD-10 Finland
Pain, unspecified
2.0
9.0
96
496
9344
FHL
Other operation on soft tissue of the foot
37.0
9.0
11
*
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.0
9.0
99
518
J01AA02
ATC
doxycycline; systemic
1.5
9.0
643
5405
M22.0
ICD-10 Finland
Recurrent dislocation of patella
4.0
8.9
25
64
M03BC01
ATC
orphenadrine (citrate); systemic
1.6
8.9
219
1460
NH2AA
NOMESCO Finland
Heel X-ray examination
9.6
8.8
17
18
J01DB01
ATC
cefalexin; oral
1.6
8.8
818
7267
NH3AA, ,
SPAT
2.3
8.8
65
291
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.6
8.7
220
1474
N39.4
ICD-10 Finland
Other specified urinary incontinence
2.3
8.7
67
305
NH3DG
NOMESCO Finland
Very extensive MRI of foot
50.4
8.7
10
*
C03CA01
ATC
furosemide; systemic
1.8
8.7
149
901
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.8
8.6
127
734
XKC03
NOMESCO Finland
Water cystometry
3.5
8.5
29
85
NHU10
NOMESCO Finland
Removal of external fixation device from ankle or foot
10.1
8.5
16
16
M70.6
ICD-10 Finland
Trochanteric bursitis
1.9
8.5
104
564
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.8
8.5
131
766
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
8.5
343
2556
X59
ICD-10 Finland
Exposure to unspecified factor
1.7
8.5
188
1218
J01DA01
ATC
[U] cefalexin
1.5
8.4
559
4601
M20.2
ICD-10 Finland
Hallux rigidus
3.4
8.4
30
91
TNH32
NOMESCO Finland
Custom moulded split, ankle or foot
4.9
8.4
18
37
9345
FHL
Tendon or tendon transplantation
+∞
8.3
8
*
M84.3
ICD-10 Finland
Stress fracture, not elsewhere classified
3.9
8.3
24
63
S93.4
ICD-10 Finland
Sprain and strain of ankle
1.7
8.3
153
944
SPAT1216
SPAT
Assessment of functional ability
1.9
8.2
104
571
H02AB04
ATC
methylprednisolone; systemic
1.9
8.2
114
645
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
2.2
8.1
67
314
NFK30
NOMESCO Finland
Angulation, rotation or displacement osteotomy of femur
17.3
8.1
12
7
B01AB10
ATC
tinzaparin; parenteral
2.0
8.0
83
425
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
8.0
234
1621
S01
ICPC
Pain/tenderness of skin
2.6
8.0
47
189
M54.5
ICD-10 Finland
Low back pain
1.5
8.0
331
2475
M09AA72
ATC
quinine, combinations with psycholeptics; systemic
4.7
7.9
18
39
SPAT1299
SPAT
Other function in accordance with podiatry nomenclature
4.7
7.9
18
39
G04BD11
ATC
fesoterodine; oral
4.1
7.8
21
52
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.5
7.8
435
3446
NHF25
NOMESCO Finland
Operation for debridement of ankle joint, arthroscopic
6.0
7.7
20
34
H02AB06
ATC
prednisolone; systemic
1.5
7.6
388
3015
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.8
7.4
125
750
WX702
NOMESCO Finland
Supraglottic ventilation device
2.2
7.4
58
267
M01AX17
ATC
nimesulide; oral
1.7
7.3
151
958
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.8
7.3
120
715
SPAT1301
SPAT
No procedures
1.5
7.3
282
2071
Q74.1
ICD-10 Finland
Congenital malformation of knee
+∞
7.3
7
*
Q65.1
ICD-10 Finland
Congenital dislocation of hip, bilateral
+∞
7.3
7
*
Q05.2
ICD-10 Finland
Lumbar spina bifida with hydrocephalus
+∞
7.3
7
*
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
3.9
7.3
21
55
D07AD01
ATC
clobetasol; topical
1.7
7.3
137
849
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.9
7.2
88
477
M24.2
ICD-10 Finland
Disorder of ligament
3.7
7.2
22
60
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.9
7.2
93
515
TNX39
NOMESCO Finland
Other orthopedic bandage, unspecified region
3.6
7.2
23
65
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
3.6
7.2
23
65
M79.2
ICD-10 Finland
Neuralgia and neuritis, unspecified
3.6
7.2
23
65
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
2.6
7.2
41
163
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
2.9
7.2
33
117
R60.0
ICD-10 Finland
Localized oedema
1.9
7.2
84
450
NGK30
NOMESCO Finland
Angulation, rotation or displacement osteotomy of knee or lower leg
8.0
7.1
15
19
WX402
NOMESCO Finland
General anaesthesia
1.6
7.1
197
1345
9165
FHL
Removal of osteosynthesis material
3.8
7.1
21
56
M66.4
ICD-10 Finland
Spontaneous rupture of other tendons
12.1
7.1
12
10
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.6
7.1
162
1056
A02BC03
ATC
lansoprazole; oral
1.6
7.0
202
1390
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
2.1
7.0
63
306
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
2.5
7.0
43
177
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.0
7.0
73
375
SPAT1249
SPAT
Treatment-related counselling outside office
1.4
7.0
367
2857
NG1AE
NOMESCO Finland
Knee joint ultrasound exmination
4.4
7.0
17
39
A01
ICPC
Pain general/multiple sites
1.9
6.9
83
448
XA402
NOMESCO Finland
ENMG
3.4
6.9
24
72
R2120
NOMESCO Finland
Counselling and guidance concerning rehabilitation services and social security
8.3
6.8
14
17
R22.4
ICD-10 Finland
Localized swelling, mass and lump, lower limb
3.1
6.8
28
93
G04BD07
ATC
tolterodine; oral
2.8
6.8
32
115
M53.1
ICD-10 Finland
Cervicobrachial syndrome
1.8
6.8
114
684
L29
ICPC
Musculoskeletal sympt/complt other
2.0
6.8
75
394
R03AC02
ATC
salbutamol; inhalant
1.4
6.8
531
4435
NH1CM
NOMESCO Finland
Ankle and foot extensive MRI examination with 3 Tesla magnet
16.8
6.8
10
6
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.8
6.7
96
548
L04AD01
ATC
ciclosporin; systemic
3.3
6.7
24
73
M48.0
ICD-10 Finland
Spinal stenosis
2.0
6.7
73
382
G47.3
ICD-10 Finland
Sleep apnoea
1.6
6.7
175
1179
L15
ICPC
Knee symptom/complaint
1.5
6.6
213
1501
M76.8
ICD-10 Finland
Other enthesopathies of lower limb, excluding foot
3.1
6.6
26
84
J01FA01
ATC
erythromycin; systemic
1.6
6.6
144
927
M21.0
ICD-10 Finland
Valgus deformity, not elsewhere classified
12.3
6.6
11
9
WX214
NOMESCO Finland
Plexus blockade at the ankle
12.3
6.6
11
9
M21.1
ICD-10 Finland
Varus deformity, not elsewhere classified
12.3
6.6
11
9
M19.9
ICD-10 Finland
Arthrosis, unspecified
2.8
6.6
32
117
M01AE02
ATC
naproxen; oral, rectal
1.4
6.5
566
4798
N04BC05
ATC
pramipexole; oral
2.2
6.5
55
261
NH1AE
NOMESCO Finland
Ankle joint ultrasound examination
6.2
6.5
16
26
NHM20
NOMESCO Finland
Excision of synovial ganglion of ankle or foot
5.7
6.5
17
30
NGL64
NOMESCO Finland
Tenodesis, shortening or lengthening of tendon of knee or lower leg
70.3
6.4
7
*
WX002
NOMESCO Finland
Sedation and analgesia
1.6
6.4
144
933
NH3CG
NOMESCO Finland
Extensive MRI of foot
7.5
6.4
14
19
G04BD12
ATC
mirabegron; oral
2.0
6.4
72
380
J02AC01
ATC
fluconazole; systemic
1.4
6.4
346
2698
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.6
6.4
168
1131
NE1AA
NOMESCO Finland
Pelvis X-ray examination
2.3
6.4
48
217
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.6
6.4
166
1116
NK4EA
NOMESCO Finland
Joint X-ray examintion with load or wrench not elsewhere classified
8.2
6.3
13
16
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.7
6.3
108
651
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
3.4
6.3
22
66
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.7
6.3
115
707
NFK20
NOMESCO Finland
Epiphysiodesis of femur
18.1
6.3
9
5
NHH99
NOMESCO Finland
Other operation on joint of ankle or foot, unspecified
18.1
6.3
9
5
Q74.3
ICD-10 Finland
Arthrogryposis multiplex congenita
+∞
6.3
6
*
Q74.9
ICD-10 Finland
Unspecified congenital malformation of limb(s)
+∞
6.3
6
*
9348
FHL
Subtalo, triple or lime cuboid arthrodesis
+∞
6.3
6
*
NHW10
NOMESCO Finland
Reoperation for deep infection in in surgery of ankle or foot
+∞
6.3
6
*
Y83.8
ICD-10 Finland
Other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.9
6.2
28
98
A28
ICPC
Limited function/disability NOS
1.8
6.2
88
501
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.7
6.2
129
819
NHF20
NOMESCO Finland
Operation for debridement of ankle joint, open
26.8
6.2
8
*
NGU10
NOMESCO Finland
Removal of external fixation device from knee or lower leg
26.8
6.2
8
*
NF1BA
NOMESCO Finland
Hip extensive X-ray examination
3.1
6.2
25
82
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
1.8
6.2
87
495
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.9
6.2
73
393
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.5
6.1
198
1395
TPH04
NOMESCO Finland
Cathetrisation of vein
1.6
6.1
168
1142
J01MA02
ATC
ciprofloxacin; systemic
1.4
6.1
274
2062
ZXE00
NOMESCO Finland
One hour or less
1.4
6.1
346
2717
ZSN00
NOMESCO Finland
Procedure related to previous procedure classified in chapter N
8.7
6.1
12
14
SAA02
NOMESCO Finland
Basic examination of mouth
1.4
6.0
735
6559
Z01.2
ICD-10 Finland
Dental examination
1.4
6.0
480
3990
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.5
6.0
176
1214
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
1.9
6.0
79
440

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
115
523
2.35
14.95
4.5
3.2
—
—
—
0
0
397
2761
1.72
14.86
12.9
8.9
1.08
1.13
inr
0.94
113
873
284
1797
1.80
14.79
4.4
3.1
—
—
—
0
0
396
2845
1.64
12.56
5.0
4.9
36.72
36.85
g/l
0.19
378
2665
416
3041
1.62
12.21
6.8
6.3
1.21
1.22
mmol/l
1.31
393
2792
264
1723
1.72
11.99
3.2
2.6
1810.89
4944.68
umol/l
1.08
244
1560
163
921
1.92
11.93
2.3
1.6
—
—
—
0
0
270
1777
1.71
11.88
4.4
3.3
1.02
1.02
kg/l
0.62
30
236
542
4262
1.58
11.44
4.9
4.7
6.38
6.46
mmol/l
0.37
516
3896
615
5003
1.58
11.02
3.6
3.0
—
—
—
0
0
172
1026
1.81
10.55
2.4
2.0
—
—
—
0
0
248
1645
1.67
10.42
4.9
4.0
—
—
—
0
0
193
1197
1.76
10.36
3.2
2.7
1.65
0.92
e6/l
1.06
118
634
283
1955
1.62
10.08
4.1
3.5
7.38
7.40
ph
2.98
55
355
440
3369
1.54
9.99
7.9
6.8
1.21
1.22
mmol/l
0.61
391
2900
296
2073
1.60
9.94
5.4
3.4
0.00
0.01
estimate
1.28
88
756
277
1913
1.61
9.85
2.5
2.1
242.44
263.57
u/l
0.12
257
1812
469
3655
1.52
9.73
2.6
2.5
—
—
—
0
0
222
1463
1.66
9.47
3.1
2.5
6.33
7.32
e6/l
0.43
200
1313
284
1992
1.59
9.40
4.0
3.0
0.53
0.37
e6/l
0.21
226
1459
686
5829
1.54
9.25
4.6
3.8
9.89
9.67
mm/h
0.17
658
5421
520
4171
1.50
9.23
6.4
6.1
0.54
0.55
e9/l
0.44
466
3625
520
4175
1.50
9.16
6.4
6.1
0.04
0.04
e9/l
0.95
465
3626
534
4319
1.50
9.02
6.4
6.5
0.20
0.18
e9/l
1.61
484
3813
919
8423
1.91
8.91
15.8
11.0
20.39
21.02
mg/l
0.23
762
6342
577
4756
1.49
8.78
9.0
8.8
3.96
3.93
e9/l
0.11
511
4141
289
2071
1.55
8.59
3.1
2.5
—
—
—
0
0
424
3303
1.49
8.45
4.2
3.0
6.01
5.90
ph
0.30
40
328
278
1987
1.55
8.32
3.5
2.9
—
—
—
0
0
209
1400
1.62
8.26
1.3
1.2
13.51
28.68
iu/ml
6.03
70
433
531
4342
1.46
8.17
6.4
6.1
1.98
1.99
e9/l
0.07
484
3868
493
3990
1.46
7.91
4.7
3.1
0.00
0.00
estimate
0.50
93
801
284
2065
1.52
7.78
6.9
6.7
—
—
—
0
0
112
642
1.84
7.75
6.8
8.6
5.05
5.15
kpa
0.61
107
616
496
4031
1.45
7.71
4.8
3.1
0.00
0.01
estimate
0.80
89
751
304
2246
1.50
7.71
3.0
3.1
2.34
2.36
mmol/l
2.29
286
2039
888
8126
1.71
7.70
15.9
11.7
139.74
139.61
mmol/l
1.10
876
7906
200
1347
1.60
7.68
1.3
1.2
1.44
10.27
u/ml
4.73
78
516
64
302
2.19
7.64
1.3
1.2
0.72
1.42
u/ml
—
6
22
111
639
1.83
7.58
6.7
8.7
1.36
0.95
mmol/l
0.56
92
526
316
2365
1.49
7.49
3.3
2.9
44.47
30.83
ng/l
0.38
195
1303
303
2251
1.49
7.44
3.4
2.5
53.93
59.35
u/l
1.22
285
2090
177
1167
1.63
7.40
1.4
1.4
428.15
511.03
titre
0.25
27
223
90
488
1.93
7.40
4.9
4.5
75.38
72.73
ng/l
0.08
82
446
202
1382
1.58
7.23
3.4
3.2
811.03
823.45
ng/l
0.02
169
1121
888
8155
1.68
7.23
16.0
11.8
3.94
3.93
mmol/l
0.31
875
7909
243
1734
1.53
7.20
2.1
2.0
1.47
0.96
mg/l
0.46
181
1273
488
3994
1.42
7.09
6.1
4.3
0.00
0.00
estimate
0.50
90
780
293
2181
1.48
7.06
4.1
3.0
20.41
96.69
e6/l
1.57
233
1633
67
333
2.08
7.03
4.1
5.9
—
—
—
0
0
37
143
2.65
6.85
2.0
1.7
8369.36
13141.63
e6/l
0.47
25
103
63
314
2.07
6.57
1.8
2.0
—
—
—
0
0
478
3944
1.40
6.41
6.5
6.5
—
—
—
0
0
452
3695
1.40
6.39
5.7
5.9
10.41
11.00
umol/l
0.56
432
3484
46
207
2.28
6.19
5.5
4.8
—
—
—
0
0
63
327
1.99
5.91
7.4
11.0
—
—
—
0
0
653
5733
1.39
5.73
7.8
6.7
80.06
78.88
u/l
0.28
633
5406
840
7715
1.50
5.71
18.9
13.8
333.75
333.82
g/l
0.07
835
7666
328
2578
1.40
5.68
1.8
1.7
97.74
96.42
pmol/l
0.18
165
1347
173
1204
1.53
5.66
2.8
3.2
881.95
599.48
ng/l
0.19
117
762
338
2674
1.39
5.62
4.6
3.5
38.85
81.13
e6/l
1.19
254
1768
396
3221
1.37
5.55
2.8
2.4
74.61
73.31
nmol/l
0.43
370
2966
132
878
1.58
5.28
1.4
1.5
—
—
—
0
0
154
1077
1.51
4.91
2.0
2.6
2.42
2.43
mmol/l
1.04
137
942
935
8860
1.66
4.83
13.7
9.9
—
—
—
0
0
822
7588
1.43
4.79
17.0
13.5
19.42
14.15
%
0.52
816
7473
719
6502
1.36
4.67
4.4
3.8
14.63
14.51
pmol/l
0.72
671
5976
146
1021
1.50
4.65
2.3
2.5
30.38
29.59
s
0.85
141
993
26
104
2.54
4.57
1.3
1.5
—
—
—
0
0
71
418
1.75
4.55
2.2
2.3
12.45
7.77
ug/l
0.37
65
378
274
2166
1.36
4.41
4.3
3.2
8.30
8.26
mmol/l
0.04
254
1896
614
5474
1.31
4.12
5.0
3.8
—
—
—
0
0
79
495
1.65
4.06
1.4
1.4
—
—
—
0
0
216
1670
1.37
3.96
3.4
3.3
572.45
261.54
mg/l
0.39
149
1119
817
7621
1.36
3.76
5.1
4.5
1.82
2.13
mu/l
0.78
785
7120
291
2371
1.32
3.74
2.4
2.2
—
—
—
0
0
223
1748
1.35
3.73
4.0
3.9
7.56
10.55
mg/mmol
0.56
157
1137
110
765
1.49
3.61
7.4
7.1
104.89
104.30
mmol/l
0.73
110
765
186
1425
1.37
3.59
1.5
1.4
21.10
20.64
nmol/l
0.16
177
1225
18
68
2.68
3.57
1.1
1.0
—
—
—
0
0
142
1041
1.42
3.55
3.2
2.3
14.29
14.48
umol/l
0.11
137
969
83
547
1.56
3.49
2.4
3.4
4.64
4.70
pmol/l
0.20
77
487
738
6811
1.30
3.47
5.6
4.6
38.29
38.41
mmol/mol
0.12
706
6431
171
1303
1.38
3.41
1.5
1.6
447.80
27797945.19
pmol/l
1.52
155
1126
988
9598
1.91
3.41
22.2
16.0
257.21
258.18
e9/l
0.19
974
9370
55
331
1.70
3.33
2.5
1.7
—
—
—
0
0
11
28
3.96
3.29
1.4
1.4
—
—
—
0
0
798
7462
1.32
3.28
4.3
3.6
5.76
5.74
mmol/l
0.21
764
6927
988
9607
1.88
3.26
22.1
15.9
89.91
89.76
fl
0.47
983
9507
90
614
1.51
3.26
3.1
2.2
11.18
12.93
nmol/l
1.40
78
573
988
9608
1.88
3.24
22.1
15.9
30.08
30.03
pg
0.37
983
9507
988
9609
1.87
3.22
22.2
16.0
4.58
4.58
e12/l
0.06
972
9366
987
9597
1.85
3.21
22.2
16.1
40.61
41.16
%
0.52
943
9137
438
3818
1.26
3.21
6.1
6.3
0.66
0.67
%
0.14
417
3600
152
1149
1.38
3.18
3.7
2.8
3.40
2.83
e6/l
0.33
80
591
988
9612
1.86
3.17
22.2
16.0
6.76
6.64
e9/l
1.03
974
9365
456
3997
1.25
3.17
6.3
6.5
8.17
8.28
%
0.33
433
3786
23
104
2.24
3.17
1.5
1.7
—
—
—
0
0
133
984
1.40
3.16
1.5
1.6
1349.22
1164.84
nmol/l
1.22
102
754
988
9615
1.85
3.12
22.3
16.1
137.08
136.93
g/l
0.13
983
9511
471
4156
1.25
3.05
6.1
6.2
29.47
30.01
%
0.55
449
3954
452
3973
1.25
3.03
6.1
6.2
2.87
2.81
%
0.26
431
3751
92
647
1.46
2.89
1.4
1.3
210.06
222.88
u/ml
0.06
84
602
119
879
1.40
2.87
3.4
2.4
23.59
24.46
%
0.25
101
771
464
4110
1.24
2.84
6.1
6.0
56.29
55.63
%
0.60
444
3904
90
633
1.46
2.83
8.6
9.1
—
—
—
0
0
178
1404
1.32
2.83
4.2
2.6
562.28
560.68
mosm/kgh2o
0.03
158
1219
10
28
3.60
2.78
4.9
2.2
147.50
109.84
ug/l
—
10
28
919
8828
1.41
2.77
10.9
8.7
28.11
27.29
u/l
0.49
900
8552
60
391
1.57
2.70
1.6
1.6
8.77
8.52
u/l
0.05
48
311
429
3784
1.23
2.69
9.9
8.5
0.00
0.00
e9/l
0.44
361
3052
20
92
2.20
2.68
2.2
4.0
—
—
—
0
0
12
43
2.81
2.65
1.6
1.5
33.00
36.13
%
—
7
32
24
120
2.02
2.62
3.9
2.4
16.86
16.76
%
0.05
14
58
20
93
2.17
2.62
1.6
1.5
—
—
—
0
0
47
291
1.64
2.61
6.4
6.8
9.64
9.12
kpa
0.99
47
280
127
964
1.36
2.61
3.3
2.3
2.37
2.42
g/l
0.40
119
891
24
121
2.01
2.57
2.3
3.4
1.24
2.37
ratio
—
6
13
36
209
1.75
2.53
2.5
2.9
—
—
—
0
0
51
327
1.59
2.48
2.3
3.2
20.90
21.54
s
0.61
42
295
7
16
4.40
2.47
1.7
1.3
—
—
—
0
0
18
363
0.49
2.46
1.9
1.5
—
—
—
0
0
91
661
1.41
2.44
2.5
2.8
11.38
10.24
g/l
1.46
83
602
223
1848
1.26
2.42
2.4
2.2
2.84
2.78
mg/l
0.17
191
1587
62
420
1.51
2.38
1.1
1.1
—
—
—
0
0
75
529
1.45
2.36
5.0
5.6
5.07
5.12
kpa
0.26
75
505
18
357
0.50
2.36
1.8
1.4
—
—
—
0
0
318
2753
1.23
2.32
3.5
3.3
30.00
31.50
u/l
0.42
302
2624
74
523
1.45
2.31
4.9
5.6
7.40
7.41
ph
—
10
46
18
354
0.50
2.30
1.8
1.4
—
—
—
0
0
11
41
2.70
2.21
2.2
3.8
—
29.13
—
0
7
11
41
2.70
2.21
1.3
2.4
—
—
—
0
0
21
109
1.95
2.11
3.9
3.2
—
—
—
0
0
20
102
1.98
2.11
1.5
1.7
—
—
—
0
0
7
20
3.52
2.05
4.4
3.2
—
—
—
0
0
214
1810
1.23
1.93
2.4
2.1
—
—
—
0
0
781
7435
1.21
1.89
3.8
3.3
1.27
1.26
mmol/l
0.24
753
7001
31
189
1.66
1.89
3.0
2.3
—
—
—
0
0
111
872
1.31
1.85
3.0
3.3
4.68
7.09
umol/l
2.80
95
737
49
335
1.49
1.85
5.0
2.6
0.18
0.11
e6/l
0.46
43
322
91
696
1.34
1.83
4.8
5.6
1.97
1.71
mmol/l
0.36
79
564
439
3986
1.18
1.83
3.3
2.8
91.09
95.01
ug/l
0.14
419
3725
813
7780
1.22
1.81
4.3
3.7
4.64
4.72
mmol/l
1.64
785
7379
68
497
1.39
1.81
1.5
1.2
—
—
—
0
0
820
7854
1.22
1.81
4.7
4.0
2.80
2.84
mmol/l
0.69
791
7394
623
5823
1.18
1.81
3.2
3.0
41.92
39.75
u/l
0.33
594
5544
40
264
1.54
1.78
1.2
1.2
—
—
—
0
0
22
124
1.79
1.77
2.0
1.4
—
—
—
0
0
32
202
1.60
1.73
1.3
1.4
256.47
300.51
ug/g
0.56
17
118
8
31
2.59
1.66
1.5
1.3
—
—
—
0
0
168
1408
1.23
1.66
3.6
3.9
2.75
1.93
ug/l
0.33
157
1287
83
637
1.33
1.65
3.2
2.3
8289.43
3217.71
u/l
0.70
29
265
45
311
1.47
1.64
2.2
2.2
—
—
—
0
0
5
133
0.37
1.62
1.0
1.0
—
—
—
0
0
24
143
1.69
1.62
6.0
2.8
8.87
9.08
kpa
0.28
24
143
278
3131
0.85
1.60
2.2
2.4
—
—
—
0
0
66
493
1.36
1.57
4.6
3.3
1.22
1.23
mmol/l
1.98
61
425
271
2392
1.18
1.55
1.3
1.4
0.65
1.77
u/ml
2.88
79
604
13
64
2.04
1.54
1.3
1.3
1.39
1.22
nmol/l
0.20
13
57
63
470
1.36
1.52
2.5
2.3
—
—
—
0
0
15
79
1.91
1.50
1.0
1.4
—
—
—
0
0
86
675
1.30
1.48
2.4
3.9
2.05
1.72
%
0.61
78
614
17
94
1.82
1.48
1.8
1.5
—
—
—
0
0
30
195
1.55
1.47
1.6
1.9
124.64
173.58
e6/l
0.19
25
149
30
195
1.55
1.47
1.6
1.9
2.83
9.97
e6/l
0.92
23
145
67
508
1.34
1.47
1.2
1.2
—
—
—
0
0
5
16
3.13
1.44
14.0
5.8
—
—
—
0
0
90
714
1.29
1.44
3.0
2.4
26.63
33.27
u/l
1.59
73
603
109
888
1.25
1.41
1.2
1.2
—
—
—
0
0
62
468
1.35
1.41
2.6
3.4
82.29
72.06
e9/l
0.59
52
340
23
143
1.62
1.36
6.0
2.8
2.13
2.46
mmol/l
0.24
18
85
23
143
1.62
1.36
6.0
2.8
5.26
4.89
kpa
2.40
23
143
327
2961
1.15
1.33
1.9
2.0
—
—
—
0
0
8
34
2.36
1.29
2.0
1.8
—
—
—
0
0
6
25
2.41
1.24
3.0
4.9
—
—
—
0
0
38
271
1.42
1.23
4.2
4.4
0.44
0.28
g/l
0.46
20
138
180
2057
0.85
1.22
1.8
1.7
—
—
—
0
0
22
140
1.58
1.21
2.5
2.4
47.73
99.52
ug/min
0.91
16
92
11
57
1.94
1.17
5.2
2.8
18.96
16.05
mg/l
0.13
11
38
96
790
1.24
1.16
2.5
2.0
333.12
367.08
nmol/l
0.98
89
733
14
81
1.74
1.09
1.0
1.1
0.31
3.16
u/ml
—
9
37
5
21
2.39
1.09
3.6
2.0
4.86
5.86
nmol/l
—
5
21
90
742
1.23
1.08
1.3
1.2
89.29
156.38
iu/ml
1.40
39
293
7
32
2.20
1.08
1.6
1.2
—
—
—
0
0
15
89
1.70
1.08
1.8
1.3
—
—
—
0
0
33
236
1.41
1.07
7.0
7.6
—
—
—
0
0
70
562
1.26
1.06
1.7
1.5
19.35
22.96
iu/l
0.47
61
461
53
411
1.31
1.05
5.3
6.0
—
—
—
0
0
140
1611
0.85
1.04
2.0
1.7
—
—
—
0
0
7
34
2.07
1.03
2.0
1.4
—
—
—
0
0
9
47
1.92
1.02
1.7
3.0
29.67
28.36
umol/l
—
9
47
217
1950
1.14
0.98
1.7
1.7
1.39
1.40
mmol/l
0.04
191
1694
46
354
1.31
0.98
3.8
4.9
126.54
129.98
g/l
0.50
46
348
798
7744
1.14
0.97
4.2
3.6
1.43
1.46
mmol/l
1.22
772
7317
7
36
1.95
0.97
1.6
1.3
129.29
185.99
mmol/24h
—
7
36
65
525
1.25
0.96
1.2
1.3
86.67
38.36
au/ml
—
6
32
26
183
1.43
0.94
1.7
2.0
—
—
—
0
0
24
167
1.45
0.92
6.1
2.7
7.41
7.41
ph
0.23
24
150
23
159
1.46
0.91
1.2
1.4
—
—
—
0
0
24
169
1.43
0.88
2.0
2.5
—
—
—
0
0
21
144
1.47
0.87
7.3
2.9
—
—
—
0
0
6
30
2.01
0.87
9.7
7.3
40.17
82.44
g/mol
—
6
25
11
64
1.73
0.86
2.9
3.8
—
—
—
0
0
12
72
1.67
0.85
1.5
1.4
4.27
1.59
u/ml
—
7
35
65
539
1.22
0.79
1.4
1.8
1.28
1.27
g/l
0.04
60
498
57
466
1.24
0.79
1.0
1.1
—
0.88
—
0
5
13
82
1.59
0.78
1.1
1.2
—
296.00
—
0
5
112
979
1.16
0.76
1.7
1.8
—
—
—
0
0
9
55
1.64
0.73
2.0
1.1
—
—
—
0
0
40
317
1.27
0.73
5.7
2.8
—
—
—
0
0
5
25
2.00
0.72
2.4
2.7
—
—
—
0
0
229
2111
1.11
0.69
1.3
1.5
2.07
2.15
g/l
0.33
147
1273
68
578
1.19
0.67
2.3
2.3
16.46
20.01
au/ml
—
5
51
22
162
1.37
0.66
1.5
1.4
21.31
19.78
u/l
0.09
16
141
26
197
1.33
0.66
1.2
1.9
3.66
3.66
mmol/l
0.01
26
183
35
277
1.27
0.66
4.2
4.8
0.61
0.63
%
0.18
35
277
14
95
1.48
0.64
1.1
1.1
5.11
2.98
u/ml
—
7
40
67
782
0.85
0.64
4.8
2.0
—
—
—
0
0
5
30
1.67
0.61
3.0
4.3
—
—
—
0
0
8
51
1.57
0.60
3.6
4.3
—
—
—
0
0
11
72
1.53
0.59
2.1
2.1
—
—
—
0
0
67
775
0.86
0.59
4.8
1.9
—
—
—
0
0
10
64
1.57
0.58
2.9
2.1
32.90
32.77
pg
—
10
64
19
140
1.36
0.58
1.1
1.1
—
—
—
0
0
68
785
0.86
0.58
4.8
2.0
—
—
—
0
0
70
606
1.17
0.57
4.5
4.6
1.00
1.07
%
0.07
29
202
8
54
1.49
0.57
1.4
1.5
4.09
6.33
ug/l
—
8
45
8
54
1.49
0.57
2.1
2.9
—
—
—
0
0
63
730
0.85
0.57
4.9
2.0
—
—
—
0
0
5
88
0.57
0.56
2.4
2.7
45.44
39.59
%
—
5
88
34
275
1.24
0.56
1.0
1.1
8.61
6.71
u/ml
0.23
17
170
19
143
1.33
0.52
1.4
1.2
3.75
5.63
u/ml
0.42
12
62
20
152
1.32
0.52
1.4
1.1
—
—
—
0
0
68
776
0.87
0.51
4.7
2.0
—
—
—
0
0
9
65
1.39
0.50
1.1
1.0
—
—
—
0
0
10
67
1.50
0.49
1.1
1.2
—
—
—
0
0
12
84
1.43
0.49
2.4
2.0
—
—
—
0
0
12
84
1.43
0.49
2.5
2.0
—
—
—
0
0
96
862
1.13
0.49
1.1
1.2
—
—
—
0
0
38
317
1.21
0.49
1.6
1.6
—
—
—
0
0
11
76
1.45
0.48
1.4
1.2
—
—
—
0
0
61
695
0.87
0.46
1.3
1.3
—
—
—
0
0
141
1301
1.10
0.45
2.1
2.5
103.83
108.98
ug/g
0.11
118
1026
32
265
1.21
0.45
1.0
1.1
0.43
1.24
u/ml
1.03
14
134
11
151
0.73
0.43
2.2
1.8
—
—
—
0
0
12
87
1.38
0.42
1.0
1.3
—
—
—
0
0
12
87
1.38
0.42
1.5
1.3
—
—
—
0
0
0
15
0.00
0.41
0.0
2.0
—
1.23
—
0
15
0
17
0.00
0.40
0.0
1.1
—
0.69
—
0
10
34
287
1.19
0.40
1.3
1.2
—
—
—
0
0
16
123
1.31
0.40
8.0
2.7
—
—
—
0
0
20
159
1.26
0.40
1.2
1.1
—
—
—
0
0
81
893
0.90
0.39
1.4
1.5
—
—
—
0
0
17
133
1.28
0.38
3.1
2.8
28.45
23.51
nmol/l
0.76
17
128
9
68
1.33
0.37
1.3
1.7
—
—
—
0
0
41
355
1.16
0.37
1.4
1.3
—
—
—
0
0
54
608
0.88
0.37
5.6
2.0
—
—
—
0
0
14
179
0.78
0.35
1.0
1.2
—
—
—
0
0
14
108
1.30
0.35
1.1
1.1
1.38
1.42
g/l
0.20
14
96
28
236
1.19
0.35
1.2
1.3
—
—
—
0
0
13
167
0.78
0.34
2.5
3.5
21.00
25.19
mg/l
—
7
105
183
1733
1.07
0.33
3.9
3.1
—
—
—
0
0
104
964
1.09
0.32
1.3
1.2
—
—
—
0
0
51
570
0.89
0.32
1.5
1.6
—
—
—
0
0
56
503
1.12
0.32
1.6
1.6
274.49
297.28
mu/l
0.54
49
450
11
143
0.77
0.32
11.2
3.8
—
—
—
0
0
7
55
1.27
0.30
1.7
1.6
0.75
1.05
g/l
—
7
55
94
873
1.08
0.29
1.4
1.4
—
—
—
0
0
7
57
1.23
0.29
1.4
1.2
—
—
—
0
0
11
85
1.30
0.28
1.9
4.1
—
—
—
0
0
8
62
1.29
0.28
1.1
1.0
—
—
—
0
0
86
798
1.08
0.27
1.2
1.3
—
—
—
0
0
63
576
1.10
0.27
4.7
4.6
0.05
0.10
%
0.49
21
171
8
64
1.25
0.27
2.1
2.1
—
—
—
0
0
279
2695
1.05
0.26
1.7
1.6
—
—
—
0
0
5
74
0.67
0.26
1.0
1.1
—
—
—
0
0
17
142
1.20
0.24
3.0
6.2
—
—
—
0
0
144
1370
1.06
0.24
1.7
1.6
—
—
—
0
0
48
527
0.91
0.24
6.2
2.5
—
—
—
0
0
10
78
1.28
0.24
1.1
1.1
—
—
—
0
0
10
78
1.28
0.24
1.0
1.1
0.31
3.88
u/ml
—
5
27
53
578
0.91
0.24
5.9
3.7
—
—
—
0
0
78
835
0.93
0.23
2.7
2.6
0.70
0.67
ug/l
0.06
43
465
5
38
1.32
0.23
1.2
1.7
1.90
6.66
nmol/l
—
5
32
19
221
0.86
0.22
1.2
1.1
—
—
—
0
0
17
144
1.18
0.22
1.1
1.1
4.43
139.19
iu/ml
—
7
46
0
11
0.00
0.21
0.0
1.3
—
1.72
—
0
11
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
18.88
—
0
10
0
12
0.00
0.21
0.0
1.3
—
93.50
—
0
12
5
43
1.16
0.21
1.6
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
2.5
—
—
—
0
0
60
557
1.08
0.21
4.3
4.4
0.36
0.58
%
0.68
22
170
10
80
1.25
0.20
6.5
8.3
6.26
6.68
mmol/l
—
10
63
55
509
1.09
0.20
2.7
4.3
3.66
15.74
ug/l
0.78
41
407
0
14
0.00
0.20
0.0
1.1
—
8.07
—
0
9
0
14
0.00
0.20
0.0
1.6
—
—
—
0
0
6
50
1.20
0.19
1.3
1.5
5.20
5.81
mmol/l
—
6
50
12
99
1.21
0.19
1.4
1.4
—
19.17
—
0
6
14
164
0.85
0.18
3.0
3.6
59.57
55.49
%
0.72
14
164
59
551
1.08
0.18
4.9
4.7
0.06
0.09
%
0.14
16
144
7
62
1.13
0.17
3.3
10.5
10.99
11.73
%
—
7
62
49
457
1.08
0.16
1.2
1.3
173.77
241.37
miu/ml
1.10
22
231
33
302
1.10
0.16
1.1
1.2
4.10
3.42
u/ml
0.10
15
172
8
72
1.11
0.16
1.3
1.1
—
—
—
0
0
14
161
0.87
0.15
1.1
1.2
—
—
—
0
0
14
161
0.87
0.15
2.8
3.3
4.43
3.99
e9/l
0.45
14
161
24
217
1.11
0.14
2.4
2.9
6.56
6.92
umol/l
0.06
16
163
74
705
1.05
0.14
5.4
3.3
—
—
—
0
0
8
96
0.83
0.13
1.3
1.5
52.38
76.87
mmol/l
—
8
85
20
221
0.90
0.13
1.2
1.1
—
—
—
0
0
56
590
0.95
0.12
1.1
1.2
—
143.08
—
0
13
52
493
1.06
0.12
1.3
1.4
—
—
—
0
0
20
219
0.91
0.11
1.6
1.5
98.80
98.02
u/ml
—
5
39
145
1486
0.97
0.10
1.6
1.5
—
—
—
0
0
115
1182
0.97
0.09
1.2
1.3
—
—
—
0
0
5
47
1.06
0.09
1.0
3.1
996.00
702.64
u/ml
—
5
47
5
48
1.04
0.09
1.0
1.3
—
—
—
0
0
5
48
1.04
0.09
1.0
1.1
1279.60
1622.85
miu/ml
—
5
48
5
48
1.04
0.09
1.0
1.5
1.38
1.53
g/l
—
5
48
11
124
0.89
0.09
1.5
1.5
—
—
—
0
0
6
54
1.11
0.09
1.5
1.1
—
—
—
0
0
6
56
1.07
0.08
1.3
1.2
—
—
—
0
0
10
88
1.14
0.08
2.0
1.7
—
—
—
0
0
7
65
1.08
0.08
3.7
2.4
—
—
—
0
0
7
66
1.06
0.08
1.4
1.4
—
—
—
0
0
28
297
0.94
0.08
1.1
1.2
—
—
—
0
0
32
336
0.95
0.07
8.6
2.6
—
—
—
0
0
229
2318
0.98
0.06
4.5
2.7
—
—
—
0
0
54
554
0.97
0.04
1.2
1.4
—
—
—
0
0
13
139
0.93
0.03
2.8
2.4
—
—
—
0
0
26
269
0.97
0.02
1.3
1.4
263.31
226.35
u/ml
0.30
16
143
257
2584
0.99
0.02
2.1
2.0
—
—
—
0
0
20
192
1.04
0.02
1.0
1.1
8.73
7.00
u/ml
0.11
11
83
22
213
1.03
0.01
1.2
1.4
78.09
144.06
pmol/l
0.59
22
208
26
267
0.97
0.01
1.0
1.1
3.43
2.25
u/ml
0.24
15
152
16
154
1.04
0.00
1.1
1.1
—
—
—
0
0
40
394
1.02
0.00
1.0
1.1
—
—
—
0
0
10
104
0.96
0.00
1.1
2.6
—
—
—
0
0
23
234
0.98
0.00
1.7
1.5
—
—
—
0
0
10
97
1.03
0.00
4.0
4.2
43.30
304.62
u/ml
—
10
91
17
173
0.98
0.00
1.2
1.1
—
—
—
0
0
21
213
0.99
0.00
1.0
1.0
3.48
6.25
u/ml
0.87
13
108
14
141
0.99
0.00
6.8
5.9
412.21
389.61
umol/l
0.23
14
131
13
129
1.01
0.00
1.4
1.2
—
—
—
0
0
26
257
1.01
0.00
1.3
1.2
—
—
—
0
0
20
205
0.98
0.00
1.4
1.3
3.85
3.41
ug/l
0.26
20
190
0
5
0.00
0.00
0.0
7.4
—
—
—
0
0
6
69
0.87
0.00
1.8
3.0
—
—
—
0
0
0
5
0.00
0.00
0.0
4.6
—
4.32
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
5
56
0.89
-0.00
1.0
1.1
—
—
—
0
0
6
59
1.02
-0.00
2.3
2.5
84.80
17.27
ug/l
—
6
59
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
66
0.91
-0.00
1.0
1.0
—
—
—
0
0
7
76
0.92
-0.00
1.1
1.4
139.77
196.32
pmol/l
—
7
76
6
67
0.89
-0.00
1.2
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.1
—
188.57
—
0
7
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
34.20
—
0
7
8
86
0.93
-0.00
2.1
1.6
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint Q17_CONGEN_DEFORMITI_FEET and mortality.

Females

Parameter HR [95% CI] p-value
Q17_CONGEN_DEFORMITI_FEET 1.245 [1.01, 1.53] 0.039
Birth year 0.997 [0.99, 1.01] 0.516

During the follow-up period (1.1.1998 — 31.12.2019), 139 out of 5121 females with Q17_CONGEN_DEFORMITI_FEET died.

Males

Parameter HR [95% CI] p-value
Q17_CONGEN_DEFORMITI_FEET 1.2 [0.98, 1.48] 0.085
Birth year 0.987 [0.98, 1.0] 0.006

During the follow-up period (1.1.1998 — 31.12.2019), 158 out of 5999 males with Q17_CONGEN_DEFORMITI_FEET died.

Mortality risk

Mortality risk for people of age

years, who have Q17_CONGEN_DEFORMITI_FEET.

N-year risk Females Males
1 0.132% 0.187%
5 0.679% 1.352%
10 1.731% 3.274%
15 3.539% 6.665%
20 6.656% 10.99%

Relationships between endpoints

Index endpoint: Q17_CONGEN_DEFORMITI_FEET – Congenital deformities of feet

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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