No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
3336 |
4. Check minimum number of eventsNone |
3336 |
5. Include endpointsNone |
3336 |
6. Filter based on genotype QC (FinnGen only) |
3336 |
Control definitions (FinnGen only)
- Control exclude
- H7_OCUMUSCLE
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to Heterophoria based on the number of shared cases.
Similar with more cases:
- Other strabismus
- Strabismus
- Disorders of ocular muscles, binocular movement, accommodation and refraction
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 35719 | 21245 | 14411 |
Only index persons | 30356 | 18385 | 11971 |
Unadjusted period prevalence (%) | |||
Whole population | 0.52 | 0.61 | 0.40 |
Only index persons | 0.59 | 0.68 | 0.46 |
Median age at first event (years) | |||
Whole population | 10.72 | 12.19 | 8.41 |
Only index persons | 13.00 | 14.96 | 10.00 |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 3336 | 2362 | 974 |
Unadjusted period prevalence (%) | 0.70 | 0.81 | 0.43 |
Median age at first event (years) | 29.79 | 27.66 | 34.95 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 2958
- Matched controls
- 29581
LabWAS
↥Mortality – FinRegistry
↥Association
Association between endpoint H7_HETEROPHORIA and mortality.
Females
Parameter | HR [95% CI] | p-value |
---|---|---|
H7_HETEROPHORIA | 1.155 [0.95, 1.41] | 0.151 |
Birth year | 0.992 [0.98, 1.0] | 0.064 |
During the follow-up period (1.1.1998 — 31.12.2019), 374 out of 14627 females with H7_HETEROPHORIA died.
Males
Parameter | HR [95% CI] | p-value |
---|---|---|
H7_HETEROPHORIA | 1.287 [1.06, 1.56] | 0.01 |
Birth year | 0.987 [0.98, 1.0] | 0.005 |
During the follow-up period (1.1.1998 — 31.12.2019), 434 out of 10607 males with H7_HETEROPHORIA died.
Mortality risk
Mortality risk for people of age
years, who have H7_HETEROPHORIA.N-year risk | Females | Males |
---|---|---|
1 | 0.067% | 0.226% |
5 | 0.553% | 1.478% |
10 | 1.46% | 3.997% |
15 | 3.001% | 7.387% |
20 | 5.346% | 11.783% |
Relationships between endpoints
↥Index endpoint: H7_HETEROPHORIA – Heterophoria
GWS hits: 2