Cholera

AB1_CHOLERA_WIDE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Primary healthcare outpatient: ICD-10 A00
  • Hospital discharge: ICD-10 A00
  • Hospital discharge: ICD-9 00[1]
  • Hospital discharge: ICD-8 00001|00010|00097|00099
  • Cause of death: ICD-10 A00
  • Cause of death: ICD-9 00[1]
  • Cause of death: ICD-8 00001|00010|00097|00099

3 out of 7 registries used, show all original rules.

73

4. Check minimum number of events

None

73

5. Include endpoints

None

73

6. Filter based on genotype QC (FinnGen only)

71

Control definitions (FinnGen only)

Control exclude
AB1_INTESTINAL_INFECTIONS

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF13

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 71 35 36
Unadjusted period prevalence (%) 0.01 0.01 0.02
Median age at first event (years) 53.68 43.33 63.74

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
73
Matched controls
730
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
A00.0
ICD-10 Finland
Cholera due to Vibrio cholerae 01, biovar cholerae
+∞
25.5
23
*
A00
ICD-10 Finland
Cholera
+∞
24.3
22
*
A00.9
ICD-10 Finland
Cholera, unspecified
+∞
19.7
18
*

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
31
128
3.47
6.11
8.2
3.6
—
—
—
0
0
9
13
7.72
4.31
1.6
1.6
—
—
—
0
0
36
193
2.71
4.18
6.6
3.6
16.19
32.65
e6/l
0.60
28
125
33
170
2.72
4.14
5.2
3.0
12.04
444.51
e6/l
0.53
26
120
30
150
2.70
3.96
3.9
2.8
—
—
—
0
0
30
153
2.63
3.78
4.4
3.0
2.54
0.30
e6/l
0.46
22
105
35
195
2.53
3.65
3.7
3.3
18.71
31.34
ng/l
0.90
21
128
41
248
2.49
3.56
14.6
12.6
1.13
1.25
inr
0.64
15
86
23
106
2.71
3.50
3.8
3.2
501.06
551.90
mosm/kgh2o
0.51
18
87
40
251
2.31
3.06
16.2
10.0
0.01
0.00
e9/l
0.49
32
208
10
30
3.69
2.72
14.7
6.1
26.21
24.38
mmol/l
—
10
30
8
20
4.36
2.65
1.4
1.5
—
—
—
0
0
21
106
2.38
2.59
1.8
1.5
1.47
1.04
mg/l
0.33
12
83
44
303
2.14
2.52
9.3
5.5
0.17
0.18
e9/l
0.18
35
273
6
12
5.34
2.45
5.5
2.8
8.22
8.65
kpa
—
6
12
6
12
5.34
2.45
5.5
2.8
5.13
4.92
kpa
—
6
12
13
53
2.77
2.44
15.8
9.5
-1.45
0.86
mmol/l
—
6
43
15
69
2.48
2.23
1.4
1.2
—
—
—
0
0
28
169
2.07
2.21
4.1
2.1
—
—
—
0
0
5
10
5.27
2.10
2.8
1.4
89.44
90.43
%
—
5
10
67
577
2.96
2.09
28.6
12.2
33.12
20.19
mg/l
1.71
57
467
39
271
1.94
2.03
10.1
5.6
—
—
—
0
0
26
158
2.00
1.98
2.0
2.2
195.33
295.55
u/l
0.38
21
151
13
59
2.46
1.98
1.7
1.7
—
—
—
0
0
41
292
1.92
1.97
9.7
5.2
0.04
0.04
e9/l
0.10
32
258
41
293
1.91
1.94
9.5
5.1
0.62
0.58
e9/l
0.46
32
260
50
383
1.97
1.90
6.0
4.1
—
—
—
0
0
42
304
1.90
1.89
9.9
5.2
1.82
1.80
e9/l
0.08
37
277
11
48
2.52
1.80
1.3
1.3
—
—
—
0
0
12
55
2.41
1.79
2.6
1.5
—
—
—
0
0
8
31
2.77
1.71
1.1
1.2
—
—
—
0
0
39
282
1.82
1.71
5.2
3.8
0.15
0.00
estimate
0.47
13
59
68
605
2.81
1.71
19.9
11.6
—
—
—
0
0
25
157
1.90
1.71
5.9
3.7
0.00
0.00
estimate
-0.00
13
53
23
141
1.92
1.68
9.3
5.7
—
—
—
0
0
36
256
1.80
1.65
10.7
6.4
1.22
1.22
mmol/l
0.27
27
217
10
44
2.47
1.63
20.9
11.3
—
—
—
0
0
38
276
1.79
1.61
6.7
5.3
0.00
0.00
estimate
-0.00
13
60
54
437
1.91
1.59
4.3
3.9
15.31
14.84
pmol/l
0.60
47
390
38
277
1.78
1.59
9.6
5.0
2.21
2.68
%
0.91
31
260
37
268
1.77
1.58
9.3
5.1
0.60
0.68
%
0.41
30
249
11
52
2.31
1.53
20.5
9.8
103.09
104.56
mmol/l
0.26
11
52
39
289
1.75
1.52
9.6
4.9
60.92
58.03
%
0.95
33
275
38
280
1.74
1.51
10.3
5.4
8.45
8.62
%
0.13
31
265
10
46
2.36
1.47
15.3
6.1
9.22
9.04
mmol/l
—
10
46
39
292
1.72
1.44
9.9
4.9
23.04
27.78
%
2.07
33
278
7
29
2.56
1.43
27.4
8.8
—
—
—
0
0
6
23
2.75
1.40
3.3
3.2
—
—
—
0
0
6
23
2.75
1.40
2.2
1.3
—
—
—
0
0
29
204
1.70
1.32
2.6
2.0
82.88
96.13
pmol/l
0.93
13
99
8
35
2.44
1.31
1.3
1.3
—
—
—
0
0
25
169
1.73
1.31
5.8
2.8
—
—
—
0
0
37
279
1.66
1.29
5.4
3.7
0.00
0.00
estimate
-0.00
13
64
22
144
1.76
1.28
4.0
3.8
—
—
—
0
0
5
19
2.75
1.23
1.0
1.2
—
—
—
0
0
43
340
1.64
1.23
8.9
4.2
6.45
6.57
mmol/l
0.16
38
309
6
26
2.42
1.21
2.2
4.1
22.92
24.22
mmol/l
—
6
26
29
209
1.64
1.19
2.9
2.7
—
—
—
0
0
20
131
1.73
1.16
3.1
1.8
2.57
2.79
mg/l
0.29
13
115
15
90
1.84
1.15
1.8
1.7
1269.11
1232.69
nmol/l
—
9
67
7
31
2.39
1.14
3.3
2.7
—
—
—
0
0
13
76
1.86
1.07
2.2
1.8
—
—
—
0
0
7
34
2.17
1.06
7.4
3.7
—
—
—
0
0
63
563
1.87
1.01
4.8
4.2
4.38
4.56
mmol/l
0.65
57
523
12
70
1.85
1.00
1.5
1.4
—
—
—
0
0
10
55
1.95
0.97
5.8
3.3
—
—
—
0
0
46
384
1.54
0.94
4.4
3.6
—
—
—
0
0
28
211
1.53
0.92
2.6
2.0
—
—
—
0
0
6
30
2.09
0.89
1.0
1.2
—
104.43
iu/ml
—
0
7
42
348
1.49
0.86
14.6
9.9
4.66
4.18
e9/l
0.39
34
311
62
559
1.72
0.86
4.7
4.2
1.34
1.45
mmol/l
1.17
56
513
21
151
1.55
0.84
3.0
3.3
86.32
121.85
mg/l
0.27
14
95
8
47
1.79
0.84
1.8
1.4
—
—
—
0
0
6
32
1.95
0.84
25.0
12.3
1.33
1.56
%
—
6
32
60
538
1.65
0.83
5.0
4.5
1.93
1.84
mu/l
0.21
53
486
22
161
1.52
0.81
5.0
4.1
14.32
16.51
mg/mmol
0.08
16
102
0
26
0.00
0.80
0.0
1.1
—
—
—
0
0
23
171
1.50
0.79
4.0
3.1
7.27
8.05
mmol/l
0.33
15
147
63
574
1.71
0.79
5.1
4.7
2.54
2.71
mmol/l
0.72
56
526
5
24
2.16
0.76
1.2
1.1
—
—
—
0
0
22
166
1.47
0.70
4.7
3.6
—
—
—
0
0
5
29
1.78
0.65
5.4
3.2
115.20
127.97
g/l
—
5
29
8
49
1.71
0.65
1.1
1.1
—
—
—
0
0
17
124
1.48
0.63
1.7
1.3
2.88
2.60
g/l
0.28
12
79
20
151
1.45
0.63
2.6
1.6
1.07
1.38
mmol/l
1.19
15
132
17
125
1.47
0.61
5.3
3.4
—
—
—
0
0
0
23
0.00
0.59
0.0
8.4
—
—
—
0
0
12
82
1.55
0.59
4.8
2.5
12.78
16.28
umol/l
0.84
12
73
57
520
1.44
0.57
7.4
5.3
40.26
39.40
mmol/mol
0.34
51
490
21
164
1.39
0.55
7.1
3.8
7.39
7.40
ph
—
8
39
9
63
1.49
0.55
1.9
1.2
—
—
—
0
0
14
101
1.48
0.54
1.1
1.2
14.52
24.42
iu/ml
—
6
32
6
40
1.54
0.53
1.5
1.3
3.19
1.17
g/l
—
6
35
18
138
1.40
0.52
2.2
1.9
—
—
—
0
0
13
94
1.47
0.50
1.2
1.3
49.67
14.07
u/ml
—
7
42
7
47
1.54
0.49
1.1
1.2
—
—
—
0
0
10
69
1.52
0.47
7.7
1.7
442.80
107.84
ug/g
—
10
46
58
538
1.38
0.45
5.5
3.8
1.46
1.25
mmol/l
0.82
53
489
5
32
1.60
0.43
29.8
12.3
0.64
0.65
%
—
5
32
8
60
1.37
0.42
3.9
2.1
9.50
4.79
umol/l
—
8
48
10
72
1.45
0.39
1.6
1.3
—
—
—
0
0
6
42
1.47
0.36
4.5
3.6
—
—
—
0
0
7
51
1.41
0.33
6.1
3.5
—
—
—
0
0
7
54
1.33
0.31
6.3
1.9
0.25
0.23
g/l
—
7
48
14
114
1.28
0.27
2.4
1.6
—
—
—
0
0
10
79
1.31
0.24
2.5
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
2.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
2.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.4
—
0.59
—
0
13
8
69
1.18
0.17
1.4
1.6
—
—
—
0
0
5
47
1.07
0.09
1.2
2.3
—
—
—
0
0
7
67
1.05
0.08
1.3
1.3
—
—
—
0
0
8
78
1.03
0.07
1.8
1.7
—
—
—
0
0
17
161
1.07
0.03
1.6
1.5
—
—
—
0
0
13
127
1.03
0.00
5.5
3.7
—
1.01
—
0
15
0
5
0.00
-0.00
0.0
1.2
—
6.48
—
0
5
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
459.43
—
0
7
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
275.29
—
0
7
0
5
0.00
-0.00
0.0
2.2
—
33.94
—
0
5
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
4.2
—
1.75
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
8.2
—
688.17
—
0
6
0
5
0.00
-0.00
0.0
4.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
5.4
—
0.57
—
0
5
0
5
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
12.7
—
1064.83
—
0
6
0
5
0.00
-0.00
0.0
2.4
—
1950.00
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
2.19
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
4.5
—
0.67
—
0
6
0
5
0.00
-0.00
0.0
1.2
—
0.33
—
0
5
0
9
0.00
-0.00
0.0
2.3
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: AB1_CHOLERA_WIDE – Cholera

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).