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Viral agents as the cause of diseases classified to other chapters

EFO Endpoint Browser PheWeb

AB1_VIRAL_INOTHER

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — B97
  • Cause of death: ICD-10 — B97

2 out of 7 registries used, show all original rules.

790

4. Check minimum number of events

None

790

5. Include endpoints

None

790

6. Filter based on genotype QC (FinnGen only)

790

Control definitions (FinnGen only)

Control exclude
AB1_BACT_BIR_OTHER_INF_AGENTS

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF5

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 5957 3647 2291
Only index persons 4638 3028 1610
Unadjusted period prevalence (%)
Whole population 0.09 0.10 0.06
Only index persons 0.09 0.11 0.06
Median age at first event (years)
Whole population 33.79 33.38 34.36
Only index persons 42.90 39.38 49.53

-FinnGen-

Key figures

All Female Male
Number of individuals 790 477 313
Unadjusted period prevalence (%) 0.15 0.16 0.14
Median age at first event (years) 48.65 42.48 58.04

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
683
Matched controls
6829
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
B97.7
ICD-10 Finland
Papillomavirus as the cause of diseases classified to other chapters
11347.3
323.0
454
*
D14.0
ICD-10 Finland
Benign neoplasm: Middle ear, nasal cavity and accessory sinuses
103.9
117.9
127
15
B97.4
ICD-10 Finland
Respiratory syncytial virus as the cause of diseases classified to other chapters
+∞
113.8
106
*
D14.1
ICD-10 Finland
Benign neoplasm: Larynx
117.4
110.0
117
12
DQB10
NOMESCO Finland
Endoscopic excision of lesion of larynx
68.7
92.1
105
18
ULA02
NOMESCO Finland
Kolposcopy
8.3
86.3
214
354
N72
ICD-10 Finland
Inflammatory disease of cervix uteri
80.4
81.6
91
13
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
7.4
74.7
200
362
ZXC10
NOMESCO Finland
Use of laser
18.7
63.7
100
62
LDA20
NOMESCO Finland
Biopsy of vaginal cervix
6.9
49.9
135
236
LDC03
NOMESCO Finland
Conisation of cervix uteri using diathermy or laser
8.0
40.9
97
138
UDH02
NOMESCO Finland
Rhinopharyngoscopy
6.5
39.8
111
199
DHA10
NOMESCO Finland
Biopsy of cavity of nose
29.6
35.1
47
17
B977, D141
ICD-10 Finland
NA
+∞
33.6
32
*
N771, B977
ICD-10 Finland
NA
+∞
31.5
30
*
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
3.8
31.4
152
482
DHB10
NOMESCO Finland
Excision of lesion of internal nose
73.5
31.2
35
5
WX408
NOMESCO Finland
General anesthesy, balanced
2.8
30.6
254
1184
LDA10
NOMESCO Finland
Curettage of cervix uteri
6.4
30.3
83
144
DQA10
NOMESCO Finland
Biopsy of larynx
36.5
29.9
38
11
QA1S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in head
35.5
29.0
37
11
DM1BD
NOMESCO Finland
Extensive CT of paranasal sinuses and face area
81.2
28.0
31
*
LDB20
NOMESCO Finland
Electrocoagulation or laser therapy of cervix uteri
19.4
27.8
42
23
D38.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Larynx
35.7
26.7
34
10
B97.2
ICD-10 Finland
Coronavirus as the cause of diseases classified to other chapters
+∞
26.2
25
*
J38.1
ICD-10 Finland
Polyp of vocal cord and larynx
32.4
26.1
34
11
ZXA00
NOMESCO Finland
Right side
2.6
24.4
216
1016
B97.8
ICD-10 Finland
Other viral agents as the cause of diseases classified to other chapters
+∞
24.1
23
*
ZXA10
NOMESCO Finland
Bilateral
2.9
24.0
166
672
R4110
NOMESCO Finland
Physiotherapy
2.6
23.6
226
1108
B977, D140
ICD-10 Finland
NA
+∞
23.0
22
*
ZXA05
NOMESCO Finland
Left side
2.6
22.2
200
944
LFB20
NOMESCO Finland
Destruction of lesion of vulva or perineum
20.9
21.9
32
16
N87.0
ICD-10 Finland
Mild cervical dysplasia
7.3
21.7
53
78
DHB20
NOMESCO Finland
Polypectomy of internal nose
11.7
21.7
40
36
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
6.5
21.2
56
92
B97.0
ICD-10 Finland
Adenovirus as the cause of diseases classified to other chapters
+∞
19.9
19
*
DNB30
NOMESCO Finland
Excision of lesion of ethmoidal sinus
+∞
19.9
19
*
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
3.5
19.3
98
316
UDQ22
NOMESCO Finland
Microlaryngoscopy
21.6
18.7
27
13
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
4.6
18.6
67
159
A63.0
ICD-10 Finland
Anogenital (venereal) warts
5.3
18.4
57
115
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.3
16.9
185
948
WX402
NOMESCO Finland
General anaesthesia
2.5
16.8
151
700
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
6.5
15.9
41
66
J33.0
ICD-10 Finland
Polyp of nasal cavity
5.9
15.4
43
77
WX002
NOMESCO Finland
Sedation and analgesia
2.4
15.2
152
739
DMB30
NOMESCO Finland
Transmaxillary excision of lesion of maxillary antrum
81.9
14.6
16
*
1420
FHL
Laryngomicroscopy
22.8
14.3
20
9
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
3.3
13.9
72
235
UDQ02
NOMESCO Finland
Direct laryngoscopy
12.4
13.7
24
20
GB3AV
NOMESCO Finland
NA
+∞
13.6
13
*
DM1DG
NOMESCO Finland
Paranasal sinuses and face area very extensive MRI examination with high intensity magnet
142.7
13.5
14
*
J33.8
ICD-10 Finland
Other polyp of sinus
6.7
13.2
33
51
2121A
ICD-9 Finland
Benign neoplasm of respiratory and intrathoracic organs, Larynx
+∞
12.5
12
*
TDM10
NOMESCO Finland
Puncture of maxillary antrum
4.3
12.1
45
111
LEB30
NOMESCO Finland
Destruction of lesion of vaginal mucosa
28.5
10.8
14
5
DPA25
NOMESCO Finland
Trephine of frontal sinus through nose
13.2
10.7
18
14
DMB35
NOMESCO Finland
Endoscopic excision of neoplasm or another lesion from maxillary sinus
+∞
10.4
10
*
R87.5
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal microbiological findings
7.1
10.2
24
35
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.0
10.1
143
797
D06BB04
ATC
podophyllotoxin; topical
2.9
10.1
62
228
DMB10
NOMESCO Finland
Radical maxillary antrotomy
30.5
9.4
12
*
ZXC00
NOMESCO Finland
Use of diathermy
12.6
9.4
16
13
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.6
8.6
348
2671
J20.5
ICD-10 Finland
Acute bronchitis due to respiratory syncytial virus
13.0
8.4
14
11
DMB00
NOMESCO Finland
Endonasal trephine of maxillary antrum
10.9
8.3
15
14
D06BB10
ATC
imiquimod; topical
3.3
8.3
41
131
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.7
8.3
194
1277
LEB00
NOMESCO Finland
Biopsy of vagina
6.4
8.1
20
32
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
7.9
169
1082
WX734
NOMESCO Finland
JET-ventilation
45.5
7.7
9
*
WX400
NOMESCO Finland
Inhalation anesthesy
3.0
7.6
43
150
J37.0
ICD-10 Finland
Chronic laryngitis
4.2
7.5
27
67
21210
ICD-8 Finland
Benign neoplasm of respiratory system, Larynx
+∞
7.3
7
*
R2110
NOMESCO Finland
Giving the first information
2.4
7.3
60
263
R49.08
ICD-10 Finland
Other specified dysphonia
5.2
7.3
21
41
J12.1
ICD-10 Finland
Respiratory syncytial virus pneumonia
15.9
7.2
11
7
H02AB06
ATC
prednisolone; systemic
1.6
7.2
285
2142
R50.9
ICD-10 Finland
Fever, unspecified
2.0
7.2
100
549
N90.0
ICD-10 Finland
Mild vulvar dysplasia
30.3
7.2
9
*
N87.1
ICD-10 Finland
Moderate cervical dysplasia
4.4
7.1
24
56
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.7
7.0
185
1252
J38.3
ICD-10 Finland
Other diseases of vocal cords
6.4
7.0
17
27
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.9
7.0
100
556
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
3.1
6.9
35
116
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.2
6.8
65
307
DPA30
NOMESCO Finland
Sphenotomy
11.1
6.8
12
11
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
2.0
6.6
82
433
127
Kela drug reimbursment
Transplant complication
5.0
6.4
19
39
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
2.9
6.4
37
133
R01AD08
ATC
fluticasone; nasal
1.6
6.3
185
1282
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.8
6.3
40
151
4509
FHL
Other measure in this category
+∞
6.3
6
*
DMA00
NOMESCO Finland
Biopsy of maxillary antrum
26.9
6.2
8
*
TPH04
NOMESCO Finland
Cathetrisation of vein
1.7
6.2
127
796
R4130
NOMESCO Finland
Speech therapy
4.1
6.1
22
55
XF400
NOMESCO Finland
ECG with 12 standard connections
1.8
6.1
99
578
A63.8
ICD-10 Finland
Other specified predominantly sexually transmitted diseases
10.1
6.0
11
11
J02AC01
ATC
fluconazole; systemic
1.5
6.0
251
1888

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
432
2599
2.46
33.56
2.9
2.1
—
—
—
0
0
290
1552
2.37
28.11
5.9
4.2
—
—
—
0
0
210
997
2.51
26.30
3.5
2.9
3.8
2.4
e6/l
0.55
113
549
54
107
5.34
26.25
2.0
1.7
—
—
—
0
0
217
1047
2.48
26.24
3.4
2.8
1.1
1.0
e6/l
0.20
120
594
301
1691
2.26
25.53
4.0
3.1
—
—
—
0
0
304
1717
2.25
25.43
4.1
3.1
0.4
0.4
e6/l
0.14
223
1279
320
1882
2.18
23.87
4.3
3.2
20.3
96.3
e6/l
1.43
238
1441
356
2242
2.07
21.63
4.9
3.7
43.3
82.1
e6/l
1.13
253
1564
125
531
2.61
19.29
8.1
7.8
1.3
1.3
mmol/l
0.14
120
507
128
579
2.44
17.21
3.2
2.3
32.9
34.6
u/l
0.17
109
496
121
551
2.41
15.98
11.3
9.0
—
—
—
0
0
58
179
3.42
15.75
3.2
3.1
—
—
—
0
0
168
883
2.15
15.74
2.3
2.1
—
—
—
0
0
502
3806
1.87
15.62
12.2
9.3
4.2
4.0
e9/l
0.98
418
3349
267
1688
1.88
14.67
9.2
6.8
—
—
—
0
0
144
733
2.18
14.55
8.6
7.4
104.3
104.0
mmol/l
0.28
144
717
325
2219
1.79
13.68
9.3
6.3
—
—
—
0
0
335
2327
1.76
13.15
1.9
1.9
93.6
95.9
pmol/l
0.42
177
1251
188
1095
1.94
13.04
3.9
3.6
616.3
375.5
ng/l
0.47
136
792
359
2566
1.73
12.58
7.6
5.2
35.8
36.0
g/l
0.39
335
2414
232
1463
1.83
12.51
3.7
3.4
—
—
—
0
0
138
731
2.08
12.46
4.9
3.5
6.0
8.0
umol/l
1.24
122
645
439
3322
1.72
12.46
8.4
6.2
0.6
0.6
e9/l
1.77
373
2897
425
3210
1.70
11.95
8.5
6.1
57.1
56.3
%
0.78
411
3041
446
3418
1.70
11.83
8.5
6.2
1.9
2.0
e9/l
1.24
397
3038
207
1289
1.82
11.49
3.3
2.6
3.7
6.2
e6/l
2.74
179
1132
657
5658
1.96
11.28
24.4
15.9
13.6
13.6
%
0.12
651
5559
435
3337
1.68
11.27
8.4
6.2
0.0
0.0
e9/l
0.23
370
2913
424
3247
1.66
10.93
9.2
6.4
27.8
29.1
%
1.50
408
3061
197
1226
1.81
10.89
3.3
2.7
548.1
561.5
mosm/kgh2o
0.35
169
1042
258
1746
1.71
10.60
5.6
4.0
7.4
7.4
ph
0.78
34
328
69
293
2.48
10.52
11.6
10.3
24.3
24.4
mmol/l
0.17
64
282
444
3460
1.65
10.52
9.0
6.6
0.2
0.2
e9/l
0.61
391
3061
42
137
3.18
10.47
2.2
1.6
92.0
109.5
u/ml
—
6
28
113
592
2.06
10.43
6.4
5.4
1.2
1.9
mmol/l
1.32
99
472
38
119
3.30
10.12
3.0
5.4
—
—
—
0
0
399
3047
1.63
10.10
9.4
6.3
0.7
0.7
%
0.09
382
2866
411
3162
1.62
10.09
9.5
6.6
8.8
8.4
%
1.88
397
2991
39
127
3.18
9.76
2.4
1.9
—
—
—
0
0
103
536
2.06
9.66
1.4
1.5
—
—
—
0
0
407
3146
1.61
9.63
9.4
6.3
2.8
2.9
%
0.44
394
2958
512
4206
1.62
9.21
5.7
4.2
28.1
2412.4
e6/l
—
8
61
145
862
1.84
9.18
1.7
1.6
—
—
—
0
0
62
268
2.43
9.11
1.7
1.3
—
—
—
0
0
390
3014
1.58
9.03
12.1
7.2
1.2
1.2
mmol/l
0.66
355
2577
42
150
2.90
8.99
2.3
1.6
—
—
—
0
0
160
986
1.78
8.98
2.9
2.4
12.9
13.5
umol/l
0.52
152
913
159
980
1.78
8.91
7.3
4.0
0.8
0.8
mmol/l
1.67
151
932
359
2729
1.58
8.88
11.5
6.6
1.2
1.2
mmol/l
1.25
343
2501
283
2036
1.61
8.83
3.1
2.3
—
—
—
0
0
383
2959
1.57
8.80
12.0
9.3
0.0
0.0
e9/l
0.03
289
2419
115
644
1.92
8.74
9.9
8.6
0.5
1.1
mmol/l
1.05
96
503
115
645
1.92
8.70
9.8
8.5
5.1
5.1
kpa
0.03
110
620
115
645
1.92
8.70
9.8
8.5
11.8
12.5
kpa
0.71
110
622
117
667
1.89
8.42
4.5
3.1
1.8
1.8
%
0.16
112
612
59
259
2.38
8.39
3.6
2.9
21.1
21.7
s
0.57
53
233
130
768
1.83
8.35
1.9
1.6
—
—
—
0
0
690
6197
1.90
8.27
23.1
14.0
40.1
39.9
%
0.23
599
4790
455
3688
1.55
8.22
7.3
4.9
6.5
6.6
mmol/l
0.79
432
3421
139
847
1.78
8.05
2.8
2.4
22.7
23.0
%
0.09
128
731
146
906
1.75
7.93
2.9
2.4
2.3
2.4
g/l
0.28
134
842
515
4320
1.55
7.74
3.6
3.5
—
—
—
0
0
90
484
1.97
7.69
3.5
2.8
77.5
71.1
e9/l
0.72
71
371
22
59
3.81
7.39
2.0
4.0
—
—
—
0
0
212
1476
1.60
7.36
2.1
1.9
—
—
—
0
0
84
449
1.97
7.30
3.6
2.8
65.3
66.9
g/l
0.93
77
414
212
1480
1.59
7.26
2.4
1.9
1.1
1.1
mg/l
0.04
175
1129
62
300
2.16
7.03
11.1
12.0
—
—
—
0
0
562
4855
1.55
6.98
10.7
7.4
80.8
78.4
u/l
0.58
537
4551
39
154
2.61
6.95
2.0
1.4
193.2
269.1
u/ml
1.22
30
88
219
1556
1.56
6.91
3.0
2.2
—
—
—
0
0
180
1224
1.61
6.84
1.8
1.6
—
—
—
0
0
133
837
1.71
6.82
10.5
6.8
1.1
1.1
mmol/l
0.05
127
790
400
3236
1.48
6.74
9.4
6.4
11.5
11.7
umol/l
0.11
385
3069
91
518
1.86
6.55
1.4
1.5
—
—
—
0
0
156
1035
1.63
6.52
3.2
2.8
2.4
2.4
mmol/l
0.36
132
920
242
1801
1.50
6.04
3.6
2.7
—
—
—
0
0
12
23
5.28
6.02
1.0
1.0
—
—
—
0
0
92
540
1.80
6.00
3.8
2.7
9.8
10.4
g/l
0.78
85
501
10
16
6.32
5.96
4.8
4.1
—
—
—
0
0
123
791
1.66
5.79
1.2
1.2
—
—
—
0
0
54
270
2.07
5.66
2.2
1.7
—
—
—
0
0
18
51
3.59
5.63
2.6
8.5
12.9
11.1
%
1.22
18
51
262
2015
1.45
5.43
4.8
3.3
2.4
2.4
mmol/l
0.07
235
1798
11
22
5.06
5.27
1.2
1.1
—
—
—
0
0
709
6597
1.73
5.21
22.0
13.0
27.3
22.2
mg/l
3.24
600
5121
49
246
2.06
5.10
1.6
2.2
1.6
1.5
g/l
0.44
42
214
511
4456
1.42
5.06
5.4
4.1
—
—
—
0
0
54
282
1.98
5.05
3.6
4.0
0.6
0.7
%
0.20
54
275
737
6953
1.89
4.91
13.8
10.0
25.4
26.7
u/l
1.03
729
6733
187
1374
1.47
4.84
1.4
1.5
22.5
20.8
nmol/l
0.80
170
1187
54
287
1.95
4.81
4.1
3.1
—
—
—
0
0
28
114
2.51
4.76
1.2
1.2
2.0
4.3
u/ml
1.75
14
45
43
212
2.09
4.71
1.1
1.2
—
—
—
0
0
540
4790
1.40
4.59
5.2
4.1
12.5
10.9
mm/h
1.37
516
4455
706
6602
1.65
4.57
23.6
14.6
139.4
139.6
mmol/l
1.96
698
6435
367
3065
1.37
4.50
4.9
4.0
—
—
—
0
0
136
952
1.52
4.43
1.4
1.3
527.7
489.8
titre
0.07
26
200
731
6911
1.77
4.38
17.0
12.0
—
—
—
0
0
10
22
4.59
4.31
1.3
1.4
—
—
—
0
0
705
6623
1.60
4.08
23.8
14.7
3.9
4.0
mmol/l
1.73
695
6436
43
225
1.96
4.04
2.3
2.0
1.9
2.7
ug/l
0.21
37
205
23
93
2.52
3.99
2.5
1.6
—
—
—
0
0
23
93
2.52
3.99
2.5
1.6
—
—
—
0
0
23
93
2.52
3.99
2.5
1.6
—
—
—
0
0
23
93
2.52
3.99
2.5
1.6
—
—
—
0
0
767
7392
2.29
3.94
29.4
19.1
249.8
254.0
e9/l
0.95
759
7214
24
100
2.44
3.92
1.3
1.2
—
—
—
0
0
203
1568
1.40
3.92
2.3
2.1
2.8
2.9
mg/l
0.20
180
1368
69
424
1.69
3.87
4.3
3.1
278.3
170.2
ng/l
0.68
60
382
225
1771
1.38
3.87
2.5
2.1
192.6
196.8
u/l
0.04
217
1679
767
7396
2.27
3.87
29.4
19.1
4.5
4.5
e12/l
2.65
757
7201
374
3183
1.33
3.85
6.0
4.7
0.0
0.0
estimate
0.50
61
596
52
295
1.82
3.84
2.5
2.3
—
—
—
0
0
71
441
1.67
3.83
1.8
1.7
1.2
1.4
g/l
0.46
64
414
24
102
2.40
3.77
1.2
1.2
—
—
—
0
0
22
90
2.49
3.74
1.5
1.9
—
—
—
0
0
111
772
1.51
3.72
2.2
1.4
—
—
—
0
0
206
1608
1.38
3.71
4.1
2.7
6315.4
6973.5
umol/l
0.07
183
1420
190
1464
1.39
3.70
1.6
1.4
2.3
2.3
g/l
0.02
107
897
357
3032
1.32
3.67
3.7
2.8
182.7
108.6
ug/l
1.21
344
2846
14
45
3.15
3.66
1.9
4.1
—
—
—
0
0
766
7398
2.17
3.58
29.5
19.2
6.9
6.7
e9/l
1.30
756
7200
136
994
1.44
3.56
1.8
1.7
959.6
1189.7
nmol/l
2.98
114
770
39
207
1.93
3.55
1.2
1.2
—
—
—
0
0
90
606
1.55
3.51
3.4
2.6
0.2
0.2
g/l
0.01
85
574
122
876
1.46
3.50
2.5
2.5
119.4
111.8
ug/g
0.12
107
697
375
3225
1.31
3.46
4.2
3.4
0.0
0.0
estimate
0.80
59
572
370
3178
1.31
3.44
4.1
3.4
0.0
0.0
estimate
0.00
61
589
200
1573
1.36
3.41
3.5
3.1
1677.7
1056.6
ng/l
1.29
176
1329
13
42
3.13
3.38
1.0
1.1
—
—
—
0
0
40
220
1.86
3.29
14.8
8.1
1.5
1.4
mg/l
0.44
40
206
95
665
1.49
3.10
22.1
19.9
1.3
1.2
inr
0.27
16
104
18
74
2.47
3.06
3.6
2.3
1.6
1.4
e9/l
—
10
43
25
120
2.12
3.01
1.2
1.1
—
—
—
0
0
23
108
2.16
2.93
1.2
1.1
—
—
—
0
0
42
244
1.76
2.93
1.2
1.2
—
—
—
0
0
15
58
2.62
2.88
1.1
1.3
—
—
—
0
0
6
9
6.71
2.87
3.2
1.0
—
—
—
0
0
6
9
6.71
2.87
3.2
1.0
—
—
—
0
0
6
9
6.71
2.87
3.2
1.0
—
—
—
0
0
71
476
1.54
2.85
2.6
2.3
12.9
17.9
au/ml
—
7
27
20
91
2.23
2.75
4.1
3.3
11.4
3.4
u/ml
1.08
20
86
56
359
1.60
2.73
5.6
6.2
—
—
—
0
0
9
24
3.78
2.68
2.0
2.9
—
—
—
0
0
113
842
1.40
2.66
1.2
1.2
—
—
—
0
0
30
164
1.86
2.56
3.9
3.9
80.5
90.5
mg/l
0.06
23
132
30
164
1.86
2.56
3.9
3.9
30.5
34.2
mg/l
0.24
23
131
27
143
1.92
2.53
5.3
4.2
53.0
36.0
umol/l
1.34
22
123
11
39
2.85
2.48
1.1
1.2
—
—
—
0
0
15
63
2.41
2.47
3.3
1.9
257.4
786.2
e6/l
—
5
19
10
34
2.97
2.42
1.1
1.2
—
—
—
0
0
9
27
3.36
2.39
3.3
1.6
—
—
—
0
0
11
40
2.77
2.38
1.5
1.8
—
—
—
0
0
65
446
1.50
2.38
7.4
4.5
95.4
76.8
ng/l
0.98
56
407
678
6465
1.34
2.22
4.6
4.6
2.8
2.8
mmol/l
0.23
647
6028
25
136
1.87
2.20
1.2
1.2
—
—
—
0
0
17
80
2.15
2.20
1.4
1.3
—
—
—
0
0
37
227
1.66
2.18
3.6
3.4
202.5
1694.9
u/ml
1.09
31
199
7
19
3.71
2.15
2.4
1.4
—
—
—
0
0
59
407
1.49
2.12
2.4
2.4
—
—
—
0
0
6
15
4.02
2.04
1.2
1.1
—
—
—
0
0
25
140
1.81
2.03
1.6
1.1
—
—
—
0
0
25
140
1.81
2.03
1.6
1.1
—
—
—
0
0
77
565
1.40
2.01
1.1
1.2
—
—
—
0
0
77
566
1.40
2.00
3.7
4.3
25.2
20.1
ug/l
0.08
58
469
16
77
2.10
1.97
2.5
2.3
—
—
—
0
0
12
51
2.37
1.95
1.9
1.4
853.7
2412.7
e6/l
—
7
33
266
2313
1.23
1.95
13.5
7.9
1.3
1.2
inr
1.18
65
688
68
493
1.42
1.91
1.4
1.3
115.1
230.6
u/ml
1.17
62
454
139
1693
0.78
1.87
4.5
3.6
—
—
—
0
0
5
12
4.19
1.82
2.4
1.6
—
—
—
0
0
52
362
1.47
1.82
3.0
2.4
—
—
—
0
0
614
5822
1.25
1.81
5.3
5.3
38.7
39.3
mmol/mol
0.89
580
5454
216
2492
0.82
1.78
2.4
2.6
—
—
—
0
0
16
81
2.00
1.75
2.4
3.1
—
—
—
0
0
65
476
1.40
1.74
2.0
2.2
12.4
12.8
nmol/l
0.15
58
427
197
1679
1.23
1.73
1.6
1.7
1.5
1.4
mmol/l
0.68
181
1432
54
383
1.44
1.73
1.3
1.2
—
—
—
0
0
8
31
2.60
1.66
2.4
1.3
—
—
—
0
0
17
90
1.91
1.66
2.8
2.6
—
—
—
0
0
36
237
1.54
1.65
1.9
1.7
—
—
—
0
0
39
262
1.51
1.64
1.1
1.3
—
4.2
—
0
7
64
475
1.38
1.60
14.8
5.1
7.4
7.4
ph
—
8
47
16
84
1.92
1.60
1.1
1.3
—
30.1
—
0
5
41
280
1.49
1.60
4.5
3.8
24.5
25.2
mmol/l
0.76
41
275
6
20
3.01
1.58
2.8
1.6
—
—
—
0
0
8
33
2.44
1.54
2.9
3.2
60.4
89.1
nmol/l
—
8
33
5
15
3.35
1.52
3.8
2.2
—
—
—
0
0
56
411
1.39
1.51
1.3
1.4
26.7
23.6
iu/l
0.26
43
346
6
21
2.87
1.51
1.3
2.2
—
—
—
0
0
631
6039
1.22
1.48
4.7
4.7
1.8
2.1
mu/l
0.79
603
5589
9
37
2.45
1.48
1.0
1.1
101.8
168.5
iu/ml
—
9
37
34
228
1.51
1.46
2.9
2.4
—
—
—
0
0
51
371
1.40
1.45
15.5
5.4
—
—
—
0
0
5
16
3.14
1.44
17.0
4.8
41.3
48.7
%
—
5
16
6
22
2.74
1.43
3.2
1.7
—
—
—
0
0
29
189
1.55
1.42
1.5
1.4
308.9
307.4
ug/g
0.01
20
108
224
1971
1.19
1.40
1.6
1.5
—
—
—
0
0
7
29
2.43
1.39
2.7
1.9
—
—
—
0
0
9
41
2.21
1.37
2.0
1.4
—
—
—
0
0
20
120
1.68
1.35
2.1
1.8
—
—
—
0
0
137
1155
1.23
1.34
1.3
1.3
41.4
32.0
iu/ml
0.24
44
356
642
6173
1.21
1.33
4.1
4.2
5.8
5.9
mmol/l
0.16
605
5687
661
6375
1.23
1.32
4.1
4.2
4.7
4.7
mmol/l
0.28
635
5980
637
6122
1.21
1.32
3.7
3.8
1.3
1.3
mmol/l
0.12
606
5695
20
121
1.67
1.31
3.2
4.5
—
—
—
0
0
9
43
2.11
1.30
1.1
1.0
—
—
—
0
0
11
55
2.01
1.27
1.5
1.6
—
—
—
0
0
124
1041
1.23
1.27
2.8
2.9
0.8
0.8
ug/l
0.19
84
655
42
570
0.72
1.26
12.5
3.9
—
—
—
0
0
13
70
1.87
1.24
1.9
2.9
—
—
—
0
0
24
155
1.57
1.24
1.0
1.1
1.8
3.8
u/ml
—
7
36
82
661
1.27
1.20
2.9
2.2
356.6
365.9
nmol/l
0.16
77
618
51
386
1.34
1.18
1.1
1.1
—
87.6
—
0
8
11
57
1.94
1.17
1.3
2.2
—
—
—
0
0
538
5121
1.16
1.15
3.8
4.0
14.5
14.6
pmol/l
0.36
512
4713
656
6347
1.20
1.12
4.0
4.1
1.4
1.5
mmol/l
0.28
629
5917
7
30
2.34
1.12
1.0
1.2
—
—
—
0
0
30
209
1.45
1.12
1.7
1.4
—
—
—
0
0
30
210
1.45
1.10
1.7
1.4
—
—
—
0
0
12
66
1.83
1.09
1.6
1.4
—
—
—
0
0
8
41
1.96
1.09
1.5
1.2
22.1
27.1
nmol/l
—
8
32
8
41
1.96
1.09
1.1
1.0
—
—
—
0
0
41
305
1.36
1.07
1.1
1.1
—
—
—
0
0
87
725
1.22
0.98
1.4
1.3
—
—
—
0
0
30
216
1.40
0.97
1.8
1.5
—
—
—
0
0
6
117
0.51
0.94
4.8
3.0
—
—
—
0
0
8
42
1.91
0.88
1.4
1.3
—
—
—
0
0
10
56
1.80
0.88
1.2
1.3
—
—
—
0
0
29
212
1.38
0.87
4.8
4.1
1.4
1.4
mmol/l
0.03
29
205
13
80
1.64
0.85
10.8
3.6
—
—
—
0
0
80
674
1.21
0.83
1.7
1.5
—
—
—
0
0
52
418
1.26
0.83
2.3
3.3
4.5
4.6
pmol/l
0.46
47
369
59
484
1.24
0.80
4.6
3.4
—
—
—
0
0
6
33
1.82
0.79
4.5
7.8
—
—
—
0
0
17
116
1.48
0.74
6.4
4.0
—
—
—
0
0
5
24
2.09
0.74
1.0
1.0
—
—
—
0
0
5
24
2.09
0.74
1.0
1.0
—
—
—
0
0
64
535
1.21
0.74
7.0
4.5
0.7
0.9
%
0.24
25
164
7
38
1.85
0.73
2.3
2.7
29.4
26.1
umol/l
—
7
38
185
1685
1.13
0.73
3.3
3.2
1050.6
284.5
mg/l
0.72
128
1097
24
177
1.37
0.71
1.3
1.2
—
2.7
—
0
22
21
152
1.39
0.69
1.3
1.2
—
—
—
0
0
110
1240
0.87
0.68
1.6
1.7
478.5
22982381.7
pmol/l
1.27
98
1053
212
1954
1.12
0.68
3.1
2.5
59.7
57.2
u/l
0.33
202
1829
18
127
1.43
0.68
1.2
1.2
—
—
—
0
0
19
136
1.41
0.67
1.2
1.8
—
—
—
0
0
7
44
1.60
0.65
1.1
2.0
—
—
—
0
0
30
234
1.29
0.63
6.7
4.9
—
—
—
0
0
21
155
1.36
0.63
1.3
1.8
693.5
892.9
e6/l
0.08
16
127
21
155
1.36
0.63
1.2
1.7
14.6
10.4
e6/l
0.15
16
124
179
1643
1.12
0.62
1.4
1.3
0.8
1.6
u/ml
1.86
32
432
5
30
1.67
0.61
1.4
4.3
—
—
—
0
0
22
165
1.34
0.61
1.0
1.1
3.7
4.9
u/ml
0.18
12
92
12
80
1.51
0.60
1.1
1.0
—
—
—
0
0
0
22
0.00
0.59
0.0
1.0
—
—
—
0
0
45
537
0.83
0.57
1.1
1.2
140.0
150.2
iu/ml
0.05
11
209
21
160
1.32
0.54
1.0
1.1
0.9
1.3
u/ml
0.27
11
79
17
125
1.37
0.54
6.7
3.9
59.1
57.6
%
0.26
17
125
6
39
1.54
0.53
1.3
1.5
—
60.2
—
0
11
190
1770
1.10
0.51
5.2
4.6
5.7
2.3
ug/l
0.73
170
1599
10
67
1.50
0.50
1.2
1.1
—
—
—
0
0
55
475
1.17
0.49
7.4
4.7
0.0
0.1
%
0.95
19
124
31
253
1.23
0.49
1.3
1.3
232.1
234.9
miu/ml
0.01
11
121
37
308
1.21
0.49
1.5
1.6
294.3
297.8
mu/l
0.03
30
279
57
494
1.17
0.49
6.5
4.2
0.4
0.5
%
0.17
18
119
7
46
1.53
0.48
2.4
1.6
1.0
1.0
g/l
—
7
46
13
94
1.39
0.46
1.1
1.2
—
—
—
0
0
23
183
1.26
0.45
1.1
1.1
0.2
2.6
u/ml
2.09
12
82
16
121
1.33
0.44
3.7
2.3
18.4
16.4
%
—
9
66
7
51
1.38
0.44
1.0
1.1
240.6
233.3
mg/l
—
7
43
8
56
1.43
0.42
1.6
1.7
—
—
—
0
0
16
122
1.32
0.42
6.7
3.6
4.2
4.2
e9/l
0.01
16
122
6
92
0.65
0.42
2.0
1.3
—
—
—
0
0
5
32
1.57
0.42
2.6
1.7
1.2
2.2
u/field
—
5
24
54
473
1.15
0.42
1.6
1.4
—
—
—
0
0
164
1534
1.09
0.41
6.3
4.6
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
0.7
—
0
12
51
447
1.15
0.40
1.7
1.4
—
—
—
0
0
187
1762
1.08
0.39
3.9
4.0
10.0
9.3
mg/mmol
0.08
123
1137
29
242
1.21
0.39
1.3
1.5
5.8
9.6
u/l
1.90
18
193
9
68
1.33
0.37
5.6
2.9
3.4
5.8
nmol/l
—
9
68
9
70
1.29
0.36
1.4
1.3
—
—
—
0
0
23
189
1.22
0.36
1.1
1.3
—
—
—
0
0
21
171
1.23
0.36
2.1
1.8
1.9
5.9
iu/l
—
9
54
13
99
1.32
0.35
1.4
1.1
—
—
—
0
0
93
856
1.10
0.34
1.6
1.5
—
—
—
0
0
56
502
1.12
0.33
7.3
4.6
0.1
0.2
%
0.11
22
150
6
46
1.31
0.33
1.2
1.2
—
—
—
0
0
29
249
1.17
0.31
5.3
4.4
0.4
0.2
g/l
0.77
17
124
7
53
1.32
0.31
1.6
1.1
—
—
—
0
0
198
1889
1.06
0.30
3.6
3.2
6.8
7.8
mmol/l
2.61
176
1603
48
429
1.13
0.30
1.1
1.2
—
—
—
0
0
16
129
1.25
0.30
3.8
2.9
—
—
—
0
0
7
55
1.28
0.30
1.6
1.1
—
—
—
0
0
9
117
0.77
0.27
2.6
1.6
—
—
—
0
0
39
437
0.89
0.27
1.4
1.7
—
—
—
0
0
11
139
0.79
0.27
2.1
3.9
29.5
26.1
mg/l
—
6
91
12
95
1.27
0.26
1.8
1.5
—
—
—
0
0
11
86
1.28
0.26
1.1
1.2
—
—
—
0
0
9
72
1.25
0.25
2.7
2.0
30.8
32.6
pg
—
9
72
24
207
1.16
0.25
1.7
2.3
—
—
—
0
0
10
78
1.29
0.24
1.4
2.2
—
—
—
0
0
17
144
1.18
0.22
2.1
1.8
205.4
216.0
pmol/l
0.14
17
136
0
11
0.00
0.21
0.0
5.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
1.8
—
0
12
0
12
0.00
0.21
0.0
2.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
173
1796
0.95
0.20
3.7
3.1
—
—
—
0
0
13
108
1.21
0.20
1.1
1.1
7.7
6.0
u/ml
—
6
38
6
53
1.13
0.18
1.0
1.2
339.0
398.2
nmol/l
—
6
48
88
835
1.06
0.18
2.0
1.6
—
—
—
0
0
7
59
1.19
0.18
4.9
2.5
—
—
—
0
0
7
60
1.17
0.18
1.4
1.2
—
—
—
0
0
7
60
1.17
0.18
1.1
1.2
—
—
—
0
0
14
119
1.18
0.17
1.1
1.0
6.0
7.5
u/ml
—
5
44
6
77
0.78
0.15
1.3
1.2
—
—
—
0
0
14
121
1.16
0.15
1.9
1.7
—
—
—
0
0
9
81
1.11
0.15
1.1
1.2
—
—
nmol/l
—
0
0
13
150
0.86
0.14
7.8
4.0
—
—
—
0
0
221
2262
0.97
0.14
4.0
3.4
57.3
34.4
ng/l
0.44
142
1444
9
106
0.85
0.13
1.0
1.3
—
—
—
0
0
75
784
0.95
0.13
1.3
1.3
—
—
—
0
0
117
1134
1.04
0.11
1.2
1.3
9.1
10.6
u/ml
0.14
37
464
138
1417
0.97
0.11
4.5
3.6
1.0
1.0
kg/l
1.08
17
199
167
1709
0.97
0.11
4.4
3.7
0.0
0.0
estimate
0.88
57
583
5
48
1.04
0.09
1.2
1.1
—
—
—
0
0
6
55
1.09
0.09
2.2
1.4
—
—
—
0
0
5
63
0.79
0.08
1.4
1.1
—
—
—
0
0
14
154
0.91
0.08
1.1
1.3
—
—
—
0
0
17
156
1.09
0.08
1.8
2.4
22.0
86.7
ug/min
1.57
11
92
28
295
0.95
0.06
1.1
1.1
—
—
—
0
0
25
236
1.06
0.06
1.2
1.7
—
—
—
0
0
15
138
1.09
0.06
1.2
1.1
—
11.6
—
0
13
10
111
0.90
0.06
1.6
1.4
—
—
—
0
0
13
119
1.09
0.06
1.1
1.3
3.1
2.6
ug/l
0.30
13
104
48
465
1.03
0.05
2.1
2.3
4.9
4.1
e9/l
0.62
40
381
32
333
0.96
0.05
2.6
2.2
7636.6
5607.2
u/l
—
9
138
31
298
1.04
0.04
1.9
1.5
—
—
—
0
0
31
300
1.03
0.03
1.9
1.7
—
—
—
0
0
45
460
0.98
0.02
6.3
3.8
1.2
1.2
mmol/l
0.26
40
404
31
301
1.03
0.02
1.9
1.7
—
—
—
0
0
56
550
1.02
0.02
4.2
3.6
—
—
—
0
0
29
282
1.03
0.02
1.9
1.7
—
—
—
0
0
31
303
1.02
0.01
1.9
1.7
—
—
—
0
0
17
165
1.03
0.00
1.2
1.1
—
—
—
0
0
20
205
0.97
0.00
9.9
11.0
—
—
—
0
0
81
808
1.00
0.00
2.0
1.9
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
2.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
90.2
—
0
5
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
16.2
—
0
8
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
7.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
4.1
—
—
—
0
0
6
61
0.98
0.00
1.2
1.2
0.9
1.3
nmol/l
—
6
56
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
14
140
1.00
0.00
2.5
2.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
18.0
—
0
7
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
7
73
0.96
0.00
5.7
2.8
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint AB1_VIRAL_INOTHER and mortality.

Females

Parameter HR [95% CI] p-value
AB1_VIRAL_INOTHER 1.297 [1.03, 1.63] 0.027
Birth year 0.997 [0.99, 1.01] 0.466

During the follow-up period (1.1.1998 — 31.12.2019), 179 out of 3038 females with AB1_VIRAL_INOTHER died.

Males

Parameter HR [95% CI] p-value
AB1_VIRAL_INOTHER 1.371 [1.09, 1.73] 0.008
Birth year 0.988 [0.98, 1.0] 0.009

During the follow-up period (1.1.1998 — 31.12.2019), 200 out of 1909 males with AB1_VIRAL_INOTHER died.

Mortality risk

Mortality risk for people of age

years, who have AB1_VIRAL_INOTHER.

N-year risk Females Males
1 0.12% 0.312%
5 0.834% 1.677%
10 2.084% 3.887%
15 3.811% 7.782%
20 6.855% 12.966%

Relationships between endpoints

↥

Index endpoint: AB1_VIRAL_INOTHER – Viral agents as the cause of diseases classified to other chapters

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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