Intracranial and intraspinal abscess and granuloma

G6_CNSABSC

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

420

4. Check minimum number of events

None

420

5. Include endpoints

None

420

6. Filter based on genotype QC (FinnGen only)

408

Control definitions (FinnGen only)

Control exclude
G6_NEUINFL

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 3266 1188 2050
Only index persons 2599 978 1621
Unadjusted period prevalence (%)
Whole population 0.05 0.03 0.06
Only index persons 0.05 0.04 0.06
Median age at first event (years)
Whole population 56.24 57.43 55.51
Only index persons 55.94 56.94 55.33

-FinnGen-

Key figures

All Female Male
Number of individuals 408 169 239
Unadjusted period prevalence (%) 0.09 0.06 0.11
Median age at first event (years) 60.49 58.38 61.98

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
420
Matched controls
4200
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G06.1
ICD-10 Finland
Intraspinal abscess and granuloma
+∞
224.8
195
*
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
45.4
180.3
111
33
G06.0
ICD-10 Finland
Intracranial abscess and granuloma
+∞
178.2
158
*
J04AB02
ATC
rifampicin; systemic
41.1
92.3
57
16
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
10.5
80.5
101
123
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
11.9
61.5
67
66
A49.9
ICD-10 Finland
Bacterial infection, unspecified
6.1
58.7
127
277
G06.2
ICD-10 Finland
Extradural and subdural abscess, unspecified
+∞
58.7
55
*
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
19.5
54.9
44
25
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
5.1
53.6
155
433
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
5.0
53.2
160
461
ZXD05
NOMESCO Finland
Urgent procedure
4.6
52.6
224
842
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
20.5
52.4
41
22
M46.3
ICD-10 Finland
Infection of intervertebral disc (pyogenic)
123.6
51.1
54
5
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
12.8
48.2
49
43
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
6.4
48.1
93
180
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
17.1
45.7
39
25
N03AX14
ATC
levetiracetam; systemic
12.2
45.0
47
43
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
11.2
44.2
49
49
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
4.4
41.2
134
401
M46.4
ICD-10 Finland
Discitis, unspecified
65.9
41.2
47
8
AA1AD
NOMESCO Finland
CT of head and brain
3.8
40.1
194
767
J01FF01
ATC
clindamycin; systemic
3.8
39.1
191
758
AA1BD
NOMESCO Finland
Extensive CT of head and brain
11.0
36.8
41
41
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
5.8
36.3
75
153
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
12.2
34.9
36
32
NA3DG
NOMESCO Finland
Lumbar spine very extensive MRI examination with high intensity magnet
55.1
34.1
40
8
AAM00
NOMESCO Finland
Puncture and evacuation of intracerebral abscess
+∞
33.8
32
*
ZXD35
NOMESCO Finland
Usual procedure
8.5
32.5
44
57
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
6.1
31.5
59
109
JN4BD
NOMESCO Finland
Extensive body CT
4.3
30.6
94
265
WX408
NOMESCO Finland
General anesthesy, balanced
3.3
29.6
167
703
A41.9
ICD-10 Finland
Sepsis, unspecified
7.0
27.9
45
71
R50.9
ICD-10 Finland
Fever, unspecified
3.7
26.7
106
355
N02AA05
ATC
oxycodone; systemic
3.3
26.1
128
490
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
9.0
25.2
32
38
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
9.2
24.8
31
36
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.9
24.2
256
1482
N03AX16
ATC
[U] pregabalin
3.0
23.4
142
611
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
4.0
23.2
74
212
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
6.9
23.0
37
58
WX882
NOMESCO Finland
High dependency care
8.3
22.8
31
40
TPH04
NOMESCO Finland
Cathetrisation of vein
2.9
22.5
141
615
SPAT1255
SPAT
Intravenous administration of medicine
4.8
22.0
54
126
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
7.6
21.9
32
45
AAM30
NOMESCO Finland
Evacuation of epidural or subdural empyema
121.4
21.8
23
*
J01CF05
ATC
flucloxacillin; systemic
4.6
21.8
56
136
R4120
NOMESCO Finland
Occupational therapy
4.5
20.8
54
132
JN4AD
NOMESCO Finland
Body CT examination
3.6
20.2
77
248
ZXE10
NOMESCO Finland
More than one and less than three hours
2.6
20.2
195
1049
R4110
NOMESCO Finland
Physiotherapy
2.7
20.0
158
771
AAM10
NOMESCO Finland
Excision of intracerebral abscess
+∞
19.9
19
*
G40.9
ICD-10 Finland
Epilepsy, unspecified
6.1
19.8
36
64
EBA15
NOMESCO Finland
Extraction of multiple teeth
5.6
19.3
38
73
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
4.6
18.9
48
115
TKC20
NOMESCO Finland
Catheterisation of bladder
4.0
18.8
59
166
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
15.3
18.4
30
21
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
3.9
18.2
58
165
B18.2
ICD-10 Finland
Chronic viral hepatitis C
14.6
18.1
30
22
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.1
17.8
85
314
J01MA12
ATC
levofloxacin; systemic
2.8
17.8
116
509
L28
ICPC
Limited function/disability (L)
2.9
17.3
101
417
Z3226
NOMESCO Finland
Physiotherapist
2.8
17.1
109
472
N02AX02
ATC
tramadol; systemic, rectal
2.4
17.0
221
1333
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
4.7
17.0
41
94
NAS20
NOMESCO Finland
Incision and debridement of infection of vertebra, unspecified
+∞
16.8
16
*
NA1DG
NOMESCO Finland
Cervical spine very extensive MRI examination with high intensity magnet
93.9
16.7
18
*
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
4.1
16.4
48
128
ZXE20
NOMESCO Finland
More than three and less than five hours
2.9
16.4
88
347
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.4
16.3
66
220
ZXC95
NOMESCO Finland
Use of surgical navigator
22.0
16.2
23
11
T36
ICD-10 Finland
Poisoning by systemic antibiotics
5.1
16.0
35
74
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
3.3
15.9
66
223
WX872
NOMESCO Finland
Intensive care
4.2
15.9
45
117
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
7.5
15.8
23
32
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.6
15.7
113
517
X59
ICD-10 Finland
Exposure to unspecified factor
2.6
15.7
109
491
A41.8
ICD-10 Finland
Other specified sepsis
7.0
15.5
24
36
WX892
NOMESCO Finland
Monitored bed care
3.6
15.2
55
170
XA800
NOMESCO Finland
Neuropsychological investigation
5.0
15.0
33
70
G09
ICD-10 Finland
Sequelae of inflammatory diseases of central nervous system
+∞
14.7
14
*
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.3
14.7
62
212
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.2
14.2
197
1195
NA2CG
NOMESCO Finland
Thoracal spine extensive MRI examination with high intensity magnet
16.5
14.1
22
14
WX110
NOMESCO Finland
Infiltration anesthesia
2.4
14.1
315
2319
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
5.1
14.0
30
62
Z3231
NOMESCO Finland
Registered nurse
2.3
14.0
144
772
I33.0
ICD-10 Finland
Acute and subacute infective endocarditis
24.8
13.9
19
8
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
3.0
13.9
69
259
A40.8
ICD-10 Finland
Other streptococcal sepsis
14.2
13.9
23
17
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
4.9
13.8
31
67
Z2446
NOMESCO Finland
Social worker
3.6
13.7
49
150
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.8
13.7
77
309
AWC00
NOMESCO Finland
Reoperation of nervous system because of deep wound infection in the nervous system
+∞
13.6
13
*
G00.9
ICD-10 Finland
Bacterial meningitis, unspecified
+∞
13.6
13
*
A46
ICD-10 Finland
Erysipelas
2.6
13.4
89
389
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.8
13.4
79
325
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
5.4
12.9
26
51
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.9
12.8
68
265
AAK00
NOMESCO Finland
Cranioplasty
+∞
12.6
12
*
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
20.8
12.6
18
9
P19
ICPC
Drug abuse
25.2
12.6
17
7
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.2
12.4
52
176
A28
ICPC
Limited function/disability NOS
2.5
12.2
91
419
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
5.3
12.1
25
50
ZXE00
NOMESCO Finland
One hour or less
2.1
12.1
176
1072
N02BF02
ATC
pregabalin; oral
3.6
12.0
41
122
F11.22
ICD-10 Finland
Addiction-induced dependence is currently independent but uses substitute intermittent medication
48.1
11.9
14
*
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
3.6
11.7
40
119
TPH07
NOMESCO Finland
Cathetrisation of artery
2.7
11.5
68
279
AAA10
NOMESCO Finland
Biopsy through craniotomy
+∞
11.5
11
*
WX402
NOMESCO Finland
General anaesthesia
2.3
11.4
100
495
R56.8
ICD-10 Finland
Other and unspecified convulsions
3.8
11.3
35
97
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
2.8
11.3
64
257
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
4.4
11.3
29
70
Z2221
NOMESCO Finland
Medical doctor
2.1
11.2
134
752
TPH40
NOMESCO Finland
Insertion of a long peripheral venous catheter
25.8
11.2
15
6
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.3
11.1
101
507
WX002
NOMESCO Finland
Sedation and analgesia
2.3
10.9
100
503
L03.1
ICD-10 Finland
Cellulitis of other parts of limb
4.5
10.9
27
63
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.5
10.9
76
339
N03AX18
ATC
lacosamide; systemic
18.4
10.8
16
9
B01AB05
ATC
enoxaparin; parenteral
2.1
10.7
151
901
S06.5
ICD-10 Finland
Traumatic subdural haemorrhage
4.6
10.7
26
60
N03AF02
ATC
oxcarbazepine; oral
4.6
10.7
26
60
C03CA01
ATC
furosemide; systemic
2.1
10.6
146
862
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
4.1
10.6
30
78
M00.0
ICD-10 Finland
Staphylococcal arthritis and polyarthritis
112.7
10.5
11
*
M46.2
ICD-10 Finland
Osteomyelitis of vertebra
112.7
10.5
11
*
3240A
ICD-9 Finland
Intracranial and intraspinal abscess, Intracranial abscess
+∞
10.5
10
*
32200
ICD-8 Finland
Intracranial and intraspinal abscess, Intracerebralis
+∞
10.5
10
*
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
19.4
10.3
15
8
ZXA00
NOMESCO Finland
Right side
2.1
10.2
131
753
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
3.4
10.1
37
115
S97
ICPC
Chronic ulcer skin
3.1
10.1
43
147
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
3.6
10.1
34
100
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
3.6
10.1
34
100
M54.5
ICD-10 Finland
Low back pain
2.0
10.1
155
949
ABC60
NOMESCO Finland
Decompression of cervical spinal cord
15.1
10.1
16
11
ZXD10
NOMESCO Finland
Scheduled procedure
2.0
10.1
172
1093
AAG00
NOMESCO Finland
Stereotactic intracranial biopsy
41.1
10.0
12
*
WX730
NOMESCO Finland
Conventional respirator
12.6
9.9
17
14
M48.0
ICD-10 Finland
Spinal stenosis
2.5
9.7
67
296
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.1
9.7
127
733
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
3.6
9.7
33
98
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
11.8
9.6
17
15
TPX10
NOMESCO Finland
Implantation of vascular injection port
4.3
9.6
25
61
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.0
9.6
45
163
J01MA02
ATC
ciprofloxacin; systemic
1.9
9.4
180
1181
M46.9
ICD-10 Finland
Inflammatory spondylopathy, unspecified
22.3
9.4
13
6
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.0
9.3
43
154
A06AD11
ATC
lactulose; oral
2.3
9.3
78
376
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
3.5
9.2
32
96
WZC00
NOMESCO Finland
Treatment plan or consultation
1.9
9.2
157
990
XX1AT
NOMESCO Finland
Other puncture with ultrasound guidance
8.6
9.2
19
23
M54.9
ICD-10 Finland
Dorsalgia, unspecified
2.5
8.8
60
264
EBA10
NOMESCO Finland
Operative extraction of tooth
2.5
8.7
59
258
G95.8
ICD-10 Finland
Other specified diseases of spinal cord
51.1
8.7
10
*
SPAT1254
SPAT
Administration of medicine
2.3
8.7
71
339
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
4.0
8.6
25
66
J01XX08
ATC
linezolid; systemic
16.7
8.6
13
8
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
4.3
8.6
22
53
N05BA01
ATC
diazepam; systemic, rectal
2.3
8.5
70
334
W19
ICD-10 Finland
Unspecified fall
2.6
8.5
51
210
F19.1
ICD-10 Finland
Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances, harmful use
28.2
8.5
11
*
J01DB01
ATC
cefalexin; oral
2.2
8.5
348
2893
AWB00
NOMESCO Finland
Reoperation for superficial infection in surgery of the nervous system
91.8
8.4
9
*
A10AB05
ATC
insulin aspart; parenteral
2.7
8.2
47
189
L70
ICPC
Infection of musculoskeletal system
17.6
8.1
12
7
Z72.2
ICD-10 Finland
Drug use
34.1
8.1
10
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.6
8.1
48
197
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
2.9
8.0
38
138
N03AX12
ATC
[U] gabapentin; oral
2.1
8.0
82
428
WX704
NOMESCO Finland
Intubation
2.8
7.9
40
151
R4190
NOMESCO Finland
Nutritional therapy
4.2
7.9
21
52
A02BC02
ATC
pantoprazole; systemic
1.9
7.9
288
2267
XF400
NOMESCO Finland
ECG with 12 standard connections
2.1
7.9
82
431
Z71.8
ICD-10 Finland
Other specified counselling
1.9
7.9
132
821
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
3.3
7.8
30
96
N06AX21
ATC
duloxetine; oral
2.4
7.8
59
271
N18
ICPC
Paralysis/weakness
6.6
7.8
19
30
N03AE01
ATC
clonazepam; systemic
3.0
7.8
34
118
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
4.7
7.7
18
40
R5110, ,
SPAT
3.0
7.7
34
119
K90
ICPC
Stroke/cerebrovascular accident
4.2
7.6
20
49
F11.25
ICD-10 Finland
Relationship caused by opiates continuously used
25.5
7.6
10
*
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
4.4
7.6
19
45
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
3.3
7.5
28
88
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.8
7.5
137
873
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
3.3
7.4
28
89
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.9
7.4
126
786
H02AB07
ATC
prednisone; oral
2.2
7.3
65
320
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
6.4
7.3
18
29
G04.9
ICD-10 Finland
Encephalitis, myelitis and encephalomyelitis, unspecified
+∞
7.3
7
*
WX750
NOMESCO Finland
Hyperbaric oxygen therapy
+∞
7.3
7
*
G992, G061,
ICD-10 Finland
+∞
7.3
7
*
P15
ICPC
Chronic alcohol abuse
3.8
7.3
22
60
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
3.7
7.2
23
65
F15.1
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, harmful use
30.6
7.2
9
*
ABC63
NOMESCO Finland
Decompression of thoracic spinal cord
30.6
7.2
9
*
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.6
7.2
41
165
T91.3
ICD-10 Finland
Sequelae of injury of spinal cord
20.4
7.2
10
5
AAD10
NOMESCO Finland
Evacuation of chronic subdural haematoma
8.1
7.2
15
19
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.2
7.1
68
345
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.7
7.1
38
148
N03AG01
ATC
valproic acid; systemic, rectal
2.9
7.1
33
119
RS221, ,
NOMESCO Finland
7.2
7.1
16
23
N29
ICPC
Neurological sympt/complt other
7.2
7.1
16
23
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.8
7.0
139
904
D64.9
ICD-10 Finland
Anaemia, unspecified
2.3
7.0
53
244
Z3229
NOMESCO Finland
Other healthcare associate professional
2.5
7.0
44
186
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.1
7.0
74
391
R33
ICD-10 Finland
Retention of urine
2.5
6.8
45
194
K08.3
ICD-10 Finland
Retained dental root
2.6
6.8
41
169
N28
ICPC
Limited function/disability (N)
9.5
6.8
13
14
R4130
NOMESCO Finland
Speech therapy
4.4
6.8
17
40
G40.10
ICD-10 Finland
Simple partial seizures
17.0
6.8
10
6
S01.0
ICD-10 Finland
Open wound of scalp
2.5
6.7
43
183
N03AX09
ATC
lamotrigine; oral
3.3
6.7
25
79
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.8
6.6
120
758
J01CF02
ATC
cloxacillin; systemic
4.3
6.6
17
41
S18
ICPC
Laceration/cut
1.7
6.6
195
1416
L89
ICD-10 Finland
Decubitus ulcer and pressure area
5.5
6.5
18
34
N02BE01
ATC
paracetamol; systemic, rectal
2.2
6.5
371
3251
ZX120
NOMESCO Finland
Intravenous
2.4
6.5
47
212
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.2
6.5
26
86
F11.24
ICD-10 Finland
Addiction-induced dependence caused by opiates active addiction
70.9
6.4
7
*
NK5AT
NOMESCO Finland
Joint injection with ultrasound guidance not elsewhere classified
14.6
6.4
10
7
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
14.6
6.4
10
7
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.8
6.4
33
126
JDB10
NOMESCO Finland
Percutaneous gastrostomy
8.3
6.4
13
16
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
8.3
6.4
13
16
F10.24
ICD-10 Finland
Alcohol depence active use
6.1
6.4
16
27
WX213
NOMESCO Finland
Lower leg blockade
18.3
6.3
9
5
I33.9
ICD-10 Finland
Acute endocarditis, unspecified
18.3
6.3
9
5
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
7.2
6.3
14
20
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.3
6.3
51
242
G03.9
ICD-10 Finland
Meningitis, unspecified
+∞
6.3
6
*
N71
ICPC
Meningitis/encephalitis
+∞
6.3
6
*
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.5
6.3
39
164
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.4
6.3
42
183
L05
ICPC
Flank/axilla symptom/complaint
2.8
6.2
31
116
J01DA01
ATC
[U] cefalexin
1.7
6.2
254
1998
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
3.1
6.2
26
88
F05.9
ICD-10 Finland
Delirium, unspecified
6.4
6.2
15
24
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.7
6.2
192
1406
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.5
6.2
39
165
B01AB10
ATC
tinzaparin; parenteral
2.3
6.1
48
224
J01MA14
ATC
moxifloxacin; systemic
2.3
6.1
46
211
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
3.7
6.1
19
53
QCB05
NOMESCO Finland
Revision of wound of skin of upper limb
8.8
6.1
12
14
H02AB09
ATC
hydrocortisone; systemic
5.7
6.0
16
29
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
5.7
6.0
16
29
RD210, ,
NOMESCO Finland
6.2
6.0
15
25

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
263
959
5.66
68.36
11.0
4.4
—
—
—
0
0
188
517
5.77
68.33
3.5
2.1
—
—
—
0
0
33
28
12.71
32.90
3.4
1.2
—
—
—
0
0
130
456
3.68
31.01
7.1
5.8
1.05
1.03
mmol/l
0.33
120
424
134
513
3.37
27.48
1.9
1.8
—
—
—
0
0
267
1537
3.02
26.24
15.9
6.4
0.62
0.67
%
0.65
259
1441
270
1585
2.97
25.20
16.4
6.4
2.84
2.87
%
0.06
262
1493
94
302
3.72
25.12
9.7
7.4
9.26
9.97
mmol/l
0.47
88
283
270
1592
2.95
24.87
17.0
6.7
9.09
8.79
%
0.63
262
1502
269
1590
2.92
24.53
14.7
6.8
—
—
—
0
0
273
1628
2.93
24.45
16.2
6.5
24.61
27.35
%
3.75
263
1538
270
1603
2.92
24.35
15.8
6.3
60.04
57.35
%
3.11
260
1517
279
1688
2.94
24.23
15.2
6.2
0.66
0.59
e9/l
3.50
247
1485
279
1691
2.94
24.09
15.4
6.2
0.04
0.04
e9/l
0.01
247
1493
136
570
3.05
23.45
5.4
3.5
0.79
0.82
mmol/l
1.82
129
535
281
1727
2.89
23.31
15.3
6.4
1.77
1.88
e9/l
0.72
254
1562
250
1450
2.79
23.15
8.8
5.0
31.83
35.54
g/l
11.88
240
1356
282
1744
2.88
22.98
16.0
6.5
0.20
0.19
e9/l
0.25
251
1562
109
418
3.17
21.75
13.7
8.7
13.14
12.14
kpa
1.15
103
401
109
418
3.17
21.75
13.7
8.7
4.98
5.08
kpa
0.56
103
399
301
1964
2.88
21.45
18.7
9.8
4.48
4.10
e9/l
1.69
266
1735
282
1786
2.76
21.19
11.8
6.9
10.82
11.66
umol/l
0.61
273
1706
108
420
3.12
20.97
13.5
8.7
0.93
1.12
mmol/l
0.19
86
344
199
1069
2.64
20.87
4.4
2.4
—
—
—
0
0
35
58
6.49
20.64
3.4
1.3
—
—
—
0
0
104
401
3.12
20.45
2.7
1.6
—
—
—
0
0
59
157
4.21
20.35
1.8
2.0
2.06
1.49
g/l
3.19
52
136
80
265
3.49
20.15
3.5
2.4
11.64
10.64
g/l
0.78
75
241
183
974
2.56
19.18
4.8
3.0
—
—
—
0
0
35
64
5.88
18.69
3.1
1.3
289.86
1793.85
e6/l
0.43
28
53
35
64
5.88
18.69
3.1
1.2
242.30
14.80
e6/l
0.66
27
51
189
1034
2.51
18.52
4.3
3.1
43.63
102.91
e6/l
0.46
150
811
161
818
2.57
18.46
4.2
2.4
—
—
—
0
0
87
326
3.10
17.79
2.9
2.5
0.19
0.21
g/l
1.61
81
304
157
812
2.49
17.10
3.0
2.0
3.31
3.19
mg/l
0.20
138
699
243
1534
2.39
16.78
12.2
6.2
1.19
1.21
mmol/l
2.54
226
1403
255
1645
2.40
16.74
16.6
14.0
1.21
1.29
inr
0.77
61
459
258
1683
2.38
16.36
13.3
7.2
1.20
1.21
mmol/l
1.92
230
1439
200
1176
2.34
16.08
5.1
3.6
130.62
99.67
e6/l
0.28
155
865
292
2026
2.45
15.86
10.6
5.1
6.82
6.75
mmol/l
0.21
279
1909
136
681
2.47
15.66
3.7
3.0
511.40
560.95
mosm/kgh2o
2.06
121
587
170
945
2.34
15.44
4.5
3.0
0.42
0.54
e6/l
0.42
134
723
230
1462
2.27
15.04
19.6
9.7
0.00
0.00
e9/l
0.54
187
1218
164
913
2.31
14.69
4.6
3.0
—
—
—
0
0
103
470
2.58
14.30
3.0
2.2
20.23
23.28
%
0.98
94
406
96
425
2.63
14.17
1.9
1.4
—
—
—
0
0
76
305
2.82
13.54
3.7
2.5
209.65
32.75
u/l
0.49
65
262
105
496
2.49
13.48
3.0
2.2
2.17
2.33
g/l
1.48
98
458
73
288
2.86
13.42
2.5
2.9
62.36
72.10
e9/l
1.26
52
227
109
534
2.41
12.86
3.1
2.2
10.90
13.09
umol/l
1.71
104
499
234
1563
2.12
12.74
4.4
2.6
—
—
—
0
0
74
302
2.76
12.73
17.0
8.0
—
—
—
0
0
38
105
3.88
12.35
10.2
1.7
—
—
—
0
0
88
398
2.53
12.30
2.7
2.7
1.58
1.82
%
1.99
81
356
109
544
2.36
12.28
3.8
2.9
2.03
2.22
e6/l
0.11
67
311
38
106
3.84
12.18
10.1
1.7
—
—
—
0
0
38
106
3.84
12.18
10.4
1.7
—
—
—
0
0
335
2611
2.40
11.90
19.8
8.0
90.20
77.56
u/l
4.95
327
2454
130
712
2.20
11.65
3.2
2.5
7.82
5.39
e6/l
0.51
115
643
24
48
5.24
11.61
13.9
2.0
—
—
—
0
0
36
100
3.84
11.61
10.6
1.7
—
—
—
0
0
32
82
4.14
11.51
11.0
1.6
—
—
—
0
0
146
845
2.12
11.31
15.4
7.3
—
—
—
0
0
121
651
2.21
11.29
4.1
3.8
652.82
275.01
ng/l
0.58
98
521
75
329
2.56
11.11
7.7
3.6
0.78
2.12
mmol/l
1.95
67
274
86
405
2.41
10.94
5.3
3.1
8.73
10.01
umol/l
0.21
71
358
24
52
4.83
10.61
1.9
1.5
—
—
—
0
0
110
583
2.20
10.58
3.8
2.7
1.35
0.92
e6/l
0.65
68
344
28
72
4.10
10.02
7.1
2.2
—
—
—
0
0
89
442
2.29
9.96
1.9
1.6
—
—
—
0
0
35
106
3.51
9.95
10.5
1.7
—
—
—
0
0
202
1365
1.92
9.76
2.3
2.0
98.87
95.65
pmol/l
0.36
104
721
80
384
2.34
9.68
1.8
1.7
—
—
—
0
0
316
2498
2.07
9.41
7.5
4.0
22.49
12.01
mm/h
13.54
302
2289
19
22
8.99
9.39
3.6
1.1
—
—
—
0
0
60
257
2.56
9.28
5.1
4.4
0.73
0.43
%
0.67
37
94
193
1319
1.86
8.71
2.5
2.3
73.19
76.78
nmol/l
0.90
172
1171
113
654
2.00
8.39
1.8
1.7
1087.80
1186.24
nmol/l
0.50
88
499
172
1145
1.85
8.36
6.2
3.7
36.25
33.58
u/l
0.48
164
1092
56
246
2.47
8.20
1.8
1.6
—
—
—
0
0
155
1004
1.86
8.18
6.5
3.9
7.39
7.40
ph
0.67
28
180
167
1108
1.84
8.16
3.9
2.6
59.31
61.75
u/l
0.17
155
1034
25
69
3.79
8.14
4.1
2.7
—
—
—
0
0
25
69
3.79
8.14
3.4
2.6
—
—
—
0
0
199
1394
1.81
8.13
3.6
2.5
184.39
144.68
ug/l
0.86
182
1277
20
32
6.51
8.11
1.6
1.2
—
—
—
0
0
53
229
2.50
8.03
3.7
3.4
7.42
7.41
ph
—
7
24
47
196
2.57
7.66
20.7
11.8
—
—
—
0
0
51
224
2.45
7.46
2.8
2.9
—
—
—
0
0
22
59
3.88
7.45
1.3
1.2
—
—
—
0
0
18
29
6.43
7.32
3.7
1.4
—
—
—
0
0
290
2316
1.81
7.24
7.3
4.3
—
—
—
0
0
19
48
4.10
6.97
1.7
2.9
—
—
—
0
0
26
82
3.31
6.96
2.0
1.5
13109.19
17232.46
e6/l
0.22
16
65
18
44
4.23
6.88
2.2
1.5
—
—
—
0
0
13
16
8.34
6.37
4.2
1.8
—
—
—
0
0
6
0
+∞
6.26
1.0
0.0
—
—
—
0
0
16
28
5.90
6.20
1.4
1.5
2540.36
2206.14
e6/l
0.14
11
21
57
286
2.15
6.11
5.5
4.5
0.80
0.86
%
0.11
35
116
23
73
3.28
6.11
1.2
1.8
—
—
—
0
0
54
267
2.17
6.01
5.7
4.6
0.06
0.18
%
1.04
32
96
13
18
7.41
5.97
1.2
1.2
462.92
180.48
iu/ml
0.68
13
18
29
108
2.81
5.89
5.2
3.2
—
—
—
0
0
15
26
5.94
5.89
1.5
1.5
23864.20
34886.88
e6/l
—
10
16
24
81
3.08
5.78
4.0
3.0
7.42
7.42
ph
0.00
18
72
16
31
5.32
5.76
1.1
3.3
—
—
—
0
0
51
251
2.17
5.74
5.2
4.7
2.96
0.14
%
0.48
28
79
26
93
2.91
5.68
1.3
1.2
—
—
—
0
0
114
740
1.74
5.64
2.0
1.7
1.91
1.28
mg/l
0.93
98
571
54
275
2.11
5.57
2.6
2.9
235.82
228.42
ng/l
0.05
47
243
49
241
2.17
5.52
5.4
3.9
97.90
80.92
ng/l
0.45
43
221
21
68
3.20
5.42
4.2
3.0
2.20
2.32
mmol/l
0.09
16
43
24
85
2.93
5.34
2.4
5.1
—
—
—
0
0
16
44
3.74
5.25
5.9
3.4
—
—
—
0
0
20
65
3.18
5.13
2.8
2.4
17.06
15.59
%
0.63
11
32
120
812
1.67
5.03
1.9
1.5
19.24
20.37
nmol/l
0.33
110
685
16
37
4.45
4.99
5.2
2.5
—
—
—
0
0
20
67
3.08
4.89
1.4
1.2
251.54
298.15
u/ml
0.27
13
34
152
1099
1.60
4.87
4.2
3.3
2.34
2.35
mmol/l
0.39
137
963
15
34
4.54
4.79
1.1
1.2
—
—
—
0
0
14
30
4.79
4.72
1.5
1.6
—
—
—
0
0
12
22
5.58
4.63
1.6
1.5
—
—
—
0
0
151
1101
1.58
4.62
5.6
3.1
6.73
7.92
mmol/l
1.99
122
921
98
643
1.68
4.58
1.8
1.4
3.00
2.59
g/l
0.80
71
408
15
37
4.17
4.45
2.3
2.4
—
—
—
0
0
173
1313
1.54
4.38
2.5
2.1
—
—
—
0
0
55
308
1.90
4.36
2.7
2.5
6.91
7.29
ug/l
0.06
50
273
36
173
2.18
4.31
3.8
3.6
—
—
—
0
0
10
16
6.37
4.31
1.7
1.9
1608.50
995.50
u/ml
—
10
16
86
1248
0.61
4.07
3.1
2.9
—
—
—
0
0
90
596
1.65
4.03
3.9
2.9
2.45
2.45
mmol/l
0.21
72
521
270
2279
1.52
3.99
7.3
3.3
77.15
52.01
u/l
2.29
254
2135
15
48
3.20
3.97
1.3
1.3
12.43
5.48
u/ml
—
7
21
12
27
4.54
3.96
5.6
2.5
—
—
—
0
0
138
1017
1.53
3.91
3.4
3.2
2404.85
1249.76
ng/l
0.53
122
870
45
246
1.93
3.84
11.8
6.6
—
—
—
0
0
18
67
2.76
3.70
1.4
1.4
—
—
—
0
0
105
740
1.56
3.61
4.5
3.6
—
—
—
0
0
25
112
2.31
3.55
17.8
10.9
1.83
1.30
mmol/l
1.48
20
97
6
6
10.12
3.50
2.0
1.5
—
—
—
0
0
27
126
2.22
3.50
3.7
3.5
0.19
0.18
g/l
0.06
17
52
17
64
2.73
3.44
3.4
2.2
—
—
—
0
0
30
148
2.11
3.40
4.2
4.0
25.16
25.09
mmol/l
0.05
30
139
201
1633
1.44
3.39
5.2
3.6
0.00
0.00
estimate
0.50
41
312
13
325
0.38
3.15
1.3
1.3
—
—
—
0
0
135
1029
1.46
3.14
3.4
3.3
1464.81
124.11
mg/l
1.02
95
682
68
447
1.62
3.11
1.3
1.2
—
—
—
0
0
10
25
4.07
3.10
1.0
1.2
—
—
—
0
0
6
8
7.59
3.06
1.3
1.5
—
—
—
0
0
5
5
10.10
2.98
1.4
1.0
—
—
—
0
0
9
22
4.16
2.89
1.8
1.8
11.91
11.45
%
—
9
22
366
3384
1.63
2.89
44.6
14.5
32.38
24.09
mg/l
5.77
340
2680
48
295
1.71
2.84
1.9
1.4
—
—
—
0
0
14
53
2.70
2.82
1.9
3.0
—
—
—
0
0
198
1644
1.39
2.77
7.2
4.8
0.00
0.00
estimate
-0.00
40
295
51
321
1.67
2.77
6.1
4.6
—
—
—
0
0
7
14
5.06
2.74
1.0
2.3
—
—
—
0
0
199
1662
1.38
2.65
5.2
3.6
0.00
0.00
estimate
-0.00
43
279
30
165
1.88
2.56
2.9
2.3
—
—
—
0
0
6
11
5.51
2.55
1.8
1.8
—
—
—
0
0
118
910
1.41
2.51
4.0
2.7
349.92
7035.69
umol/l
3.77
101
790
374
3501
1.62
2.50
45.5
17.0
139.05
139.70
mmol/l
5.38
369
3404
10
32
3.18
2.45
1.5
1.3
—
—
—
0
0
19
90
2.16
2.42
1.3
1.4
201.83
284.62
ug/g
1.19
13
52
26
139
1.93
2.42
8.2
4.5
—
—
—
0
0
8
22
3.69
2.37
1.0
1.2
—
—
—
0
0
62
426
1.53
2.36
1.4
1.3
525.00
422.74
titre
0.13
16
95
374
3512
1.59
2.33
45.7
17.2
3.99
3.99
mmol/l
0.06
368
3412
54
365
1.55
2.22
2.6
4.4
5.18
36.33
ug/l
0.84
46
310
8
24
3.38
2.19
1.1
1.8
—
—
—
0
0
6
14
4.33
2.16
1.2
1.1
—
—
—
0
0
18
88
2.09
2.14
1.6
1.3
6.23
8.63
u/l
0.60
13
73
165
1375
1.33
2.11
4.8
3.7
35.58
64.82
ng/l
0.58
129
986
6
15
4.04
2.04
1.7
1.3
—
—
—
0
0
5
11
4.59
1.94
1.2
1.6
—
—
—
0
0
6
16
3.79
1.94
4.3
2.9
—
—
—
0
0
6
16
3.79
1.94
3.0
2.8
43466.67
35844.06
ug/l
—
6
16
134
1098
1.32
1.89
4.2
3.8
25.51
9.45
mg/mmol
0.87
95
713
5
12
4.20
1.83
1.2
1.1
—
—
—
0
0
48
332
1.50
1.80
2.1
2.3
13.06
13.58
nmol/l
0.12
43
302
316
2920
1.33
1.76
44.9
17.4
15.35
15.06
%
0.44
309
2874
10
41
2.47
1.65
1.9
1.7
82.09
90.15
%
—
10
41
8
32
2.53
1.60
1.8
1.3
—
—
—
0
0
22
357
0.60
1.59
1.2
1.6
—
—
—
0
0
6
20
3.03
1.58
2.7
1.4
—
—
—
0
0
10
44
2.30
1.56
1.0
1.2
—
—
—
0
0
9
40
2.28
1.41
2.0
2.2
—
—
—
0
0
110
911
1.28
1.40
1.4
1.4
—
—
—
0
0
5
17
2.96
1.36
1.0
1.1
—
—
—
0
0
12
61
2.00
1.34
1.2
1.0
—
—
—
0
0
33
227
1.49
1.31
1.2
1.2
—
—
—
0
0
13
69
1.91
1.30
1.3
1.1
—
—
—
0
0
22
138
1.63
1.29
2.4
1.8
—
—
—
0
0
16
92
1.77
1.27
1.3
1.2
—
—
—
0
0
28
188
1.52
1.25
2.1
2.7
0.38
0.12
e6/l
1.32
28
181
11
56
1.99
1.23
1.9
1.5
—
—
—
0
0
5
19
2.65
1.22
1.0
1.1
—
—
—
0
0
322
3036
1.26
1.21
4.8
4.4
1.81
1.95
mu/l
1.25
286
2756
37
266
1.43
1.19
7.4
3.7
—
—
—
0
0
11
57
1.95
1.18
4.3
2.4
—
—
—
0
0
5
113
0.44
1.14
14.6
12.3
—
—
—
0
0
31
218
1.46
1.13
1.4
1.7
—
—
—
0
0
50
383
1.35
1.12
1.5
1.3
—
—
—
0
0
88
729
1.26
1.12
5.4
3.9
1.02
1.02
kg/l
0.16
12
101
50
386
1.34
1.07
3.3
2.5
286.42
130.32
ug/g
0.56
43
313
18
275
0.64
1.06
1.1
1.4
—
—
—
0
0
7
33
2.14
1.06
1.3
1.8
—
—
—
0
0
9
46
1.98
1.04
1.4
1.9
16.00
16.06
ug/l
—
9
46
9
46
1.98
1.04
1.1
1.1
—
—
—
0
0
12
201
0.59
1.03
1.1
1.5
—
—
—
0
0
13
76
1.73
1.00
1.4
1.3
2.90
3.14
u/ml
—
5
12
17
108
1.60
0.98
1.7
1.6
—
—
—
0
0
7
37
1.91
0.94
1.1
1.1
—
—
—
0
0
63
514
1.27
0.92
1.3
1.3
37.19
35.65
iu/ml
0.03
19
172
11
63
1.77
0.91
1.9
1.8
—
—
—
0
0
5
102
0.48
0.90
1.0
1.6
—
—
—
0
0
367
3549
1.27
0.87
30.3
13.6
—
—
—
0
0
11
64
1.74
0.87
4.8
3.2
5.03
4.53
e9/l
0.31
11
64
85
727
1.21
0.82
1.9
1.8
532.55
9421920.38
pmol/l
0.50
75
605
8
47
1.72
0.81
1.4
1.1
1.40
1.45
g/l
—
8
42
6
33
1.83
0.79
1.0
1.2
—
—
—
0
0
6
33
1.83
0.79
1.2
1.1
—
—
—
0
0
8
48
1.68
0.79
1.1
1.1
—
16.44
—
0
5
160
1452
1.16
0.78
4.8
4.8
1.81
2.35
ug/l
1.20
138
1306
11
67
1.66
0.76
5.6
3.7
64.00
57.72
%
0.90
11
67
329
3163
1.19
0.73
6.8
5.9
40.51
40.23
mmol/mol
0.17
304
2936
13
84
1.57
0.72
1.3
1.3
—
—
—
0
0
24
177
1.38
0.72
1.3
1.3
1204.59
323.66
u/ml
0.90
24
161
7
40
1.76
0.71
1.7
1.2
—
—
—
0
0
327
3384
0.85
0.69
4.4
4.6
4.35
4.61
mmol/l
4.56
300
3132
5
27
1.86
0.68
1.0
1.2
—
—
—
0
0
325
3362
0.85
0.66
4.3
4.5
1.36
1.43
mmol/l
2.00
291
3093
255
2414
1.14
0.66
4.7
3.9
—
—
—
0
0
12
79
1.53
0.63
2.7
1.9
—
—
—
0
0
0
23
0.00
0.58
0.0
1.3
—
1.52
—
0
23
370
3617
1.19
0.53
25.1
10.9
29.55
27.48
u/l
0.87
363
3491
6
39
1.55
0.53
2.0
1.9
31.33
33.26
pg
—
6
39
6
39
1.55
0.53
1.3
1.2
—
—
—
0
0
6
40
1.51
0.52
1.5
1.3
—
—
nmol/l
—
0
0
10
144
0.69
0.50
1.1
1.1
—
—
—
0
0
7
46
1.53
0.48
1.9
1.2
—
—
—
0
0
24
191
1.27
0.47
1.3
1.2
—
—
—
0
0
257
2463
1.11
0.47
4.0
3.7
14.97
14.79
pmol/l
0.50
232
2213
94
852
1.13
0.47
2.9
2.9
0.61
0.72
ug/l
1.24
60
545
336
3440
0.88
0.43
4.9
5.1
2.49
2.74
mmol/l
6.12
305
3164
5
31
1.62
0.43
1.0
1.3
—
—
—
0
0
111
1023
1.12
0.42
4.8
4.0
—
—
—
0
0
13
97
1.35
0.40
1.2
1.2
—
—
—
0
0
0
19
0.00
0.39
0.0
1.4
—
—
—
0
0
0
19
0.00
0.39
0.0
1.0
—
260.36
—
0
11
19
152
1.26
0.37
2.3
2.8
—
—
—
0
0
22
180
1.23
0.36
1.3
1.3
—
—
—
0
0
6
41
1.47
0.36
1.3
1.3
—
—
—
0
0
14
108
1.31
0.35
1.5
1.2
—
—
—
0
0
6
43
1.40
0.35
1.7
1.2
—
—
—
0
0
55
495
1.13
0.32
1.2
1.3
4.42
10.54
u/ml
0.82
19
197
29
249
1.18
0.31
1.8
1.4
—
—
—
0
0
45
401
1.14
0.31
1.4
1.3
—
—
—
0
0
21
175
1.21
0.30
6.3
3.9
—
—
—
0
0
8
62
1.30
0.28
1.3
1.7
—
—
—
0
0
95
890
1.09
0.27
6.5
3.8
0.00
0.01
estimate
0.50
40
280
16
192
0.83
0.26
1.1
1.2
63.80
154.97
iu/ml
—
5
73
32
283
1.14
0.25
4.7
3.3
—
—
—
0
0
38
341
1.13
0.24
1.8
1.4
—
—
—
0
0
25
219
1.15
0.22
3.3
2.3
—
—
—
0
0
321
3263
0.93
0.22
3.9
4.1
1.42
1.32
mmol/l
1.21
292
2996
7
92
0.76
0.22
1.1
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
5.4
—
—
—
0
0
0
10
0.00
0.21
0.0
2.7
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
97
920
1.07
0.21
5.3
3.3
—
—
—
0
0
8
105
0.76
0.21
10.1
4.8
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
26
231
1.13
0.20
6.7
2.9
3.86
6.02
e9/l
1.01
19
186
380
3764
1.10
0.19
54.8
21.5
261.89
244.47
e9/l
4.29
373
3667
380
3764
1.10
0.19
55.4
21.6
38.36
40.59
%
8.99
355
3523
380
3765
1.10
0.19
54.4
21.4
91.15
91.14
fl
0.01
375
3708
6
53
1.13
0.18
7.2
2.9
—
—
—
0
0
380
3766
1.09
0.18
54.3
21.4
30.05
30.39
pg
3.00
375
3709
380
3767
1.09
0.17
54.6
21.5
4.28
4.53
e12/l
13.01
370
3658
380
3768
1.09
0.16
54.6
21.5
7.47
6.70
e9/l
5.59
371
3656
380
3769
1.09
0.16
55.0
21.6
126.92
137.08
g/l
21.34
374
3706
332
3312
1.01
0.01
4.7
4.6
6.12
6.02
mmol/l
0.49
299
3017
69
697
0.99
0.01
1.4
1.2
1.38
1.39
u/ml
0.00
12
212
10
103
0.97
0.00
1.0
1.1
—
—
—
0
0
93
932
1.00
0.00
1.8
1.7
1.35
1.44
mmol/l
0.62
78
779
15
147
1.02
0.00
1.3
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
1.84
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.9
—
8293.33
—
0
9
0
7
0.00
-0.00
0.0
1.4
—
39.14
—
0
7
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
6.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint G6_CNSABSC and mortality.

Females

Parameter HR [95% CI] p-value
G6_CNSABSC 2.858 [2.2, 3.71] < 0.001
Birth year 0.996 [0.99, 1.0] 0.345

During the follow-up period (1.1.1998 — 31.12.2019), 249 out of 827 females with G6_CNSABSC died.

Males

Parameter HR [95% CI] p-value
G6_CNSABSC 3.057 [2.48, 3.77] < 0.001
Birth year 0.984 [0.97, 0.99] 0.002

During the follow-up period (1.1.1998 — 31.12.2019), 456 out of 1360 males with G6_CNSABSC died.

Mortality risk

Mortality risk for people of age

years, who have G6_CNSABSC.

N-year risk Females Males
1 0.342% 0.607%
5 2.032% 3.043%
10 4.479% 7.957%
15 7.857% 15.197%
20 13.336% 24.356%

Relationships between endpoints

Index endpoint: G6_CNSABSC – Intracranial and intraspinal abscess and granuloma

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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