retinal detachment: An eye emergency condition which may lead to blindness if left untreated. It is characterized by the separation of the inner retina layers from the underlying pigment epithelium. Causes include trauma, advanced diabetes mellitus, high myopia, and choroid tumors. Symptoms include sudden appearance of floaters, sudden light flushes, and blurred vision.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
1640 |
4. Check minimum number of eventsNone |
1640 |
5. Include endpointsNone |
1640 |
6. Filter based on genotype QC (FinnGen only) |
1581 |
Control definitions (FinnGen only)
- Control exclude
- H7_CHOROIDRETINA
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H35
- Name in latin
- Separatio stratorum retinae
Similar endpoints
↥List of similar endpoints to
Separation of retinal layers (serosa)
based on the number of shared cases.
Similar with more cases:
- Other retinal disorders
- Disorders of choroid and retina
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 10471 | 3365 | 7063 |
| Only index persons | 10254 | 3320 | 6934 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.16 | 0.10 | 0.20 |
| Only index persons | 0.22 | 0.12 | 0.26 |
| Median age at first event (years) | |||
| Whole population | 49.96 | 56.13 | 47.11 |
| Only index persons | 49.96 | 56.05 | 47.04 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1581 | 586 | 995 |
| Unadjusted period prevalence (%) | 0.36 | 0.21 | 0.46 |
| Median age at first event (years) | 52.44 | 54.40 | 51.29 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1640
- Matched controls
- 16400
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
XCK10
NOMESCO Finland
Photography of fundus of eye
9.9
313.1
415
541
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
21.5
307.7
398
241
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
368.5
307.7
371
13
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
19.8
307.7
563
422
CKC12
NOMESCO Finland
Photocoagulation of retina
179.1
307.7
231
15
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
57.3
307.7
232
47
XCD20
NOMESCO Finland
Photoangiography of eye
313.3
307.7
306
12
H35.7
ICD-10 Finland
Separation of retinal layers
+∞
307.7
1640
*
H35.31
ICD-10 Finland
Senile macular degeneration (atrophic)(exudative)
927.8
307.7
363
5
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
288.4
307.7
266
11
XCW99
NOMESCO Finland
Other investigative procedure of eye
15.6
307.7
565
535
CK9F4
NOMESCO Finland
Fluorescein angiography (FAG) of choroid and retina
721.8
198.6
192
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
4.8
174.2
511
1410
CK9G4
NOMESCO Finland
Iridocyanine green angiography (ICGA) of choroid and retina
+∞
126.7
120
*
ZX198
NOMESCO Finland
Other local administration
23.7
91.3
66
29
CM2X4
NOMESCO Finland
Follow-up OCT of age-related macular degeneration lesions
916.7
89.6
87
*
CK2Y4
NOMESCO Finland
OCT video recording of ocular fundus
872.2
85.4
83
*
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
26.1
83.3
58
23
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
32.9
79.0
51
16
ZXA10
NOMESCO Finland
Bilateral
3.2
78.1
383
1426
S01BC03
ATC
diclofenac; ophthalmic
8.9
77.1
98
116
WX140
NOMESCO Finland
Parabulbar anesthesy
9.1
68.1
85
98
H33.0
ICD-10 Finland
Retinal detachment with retinal break
685.5
67.5
66
*
1LA01, ,
NOMESCO Finland
+∞
67.1
64
*
CKC10
NOMESCO Finland
Local photocoagulation of retina
236.3
66.7
68
*
XCH00
NOMESCO Finland
Eye pressure measurement
5.9
63.4
118
212
S01EC01
ATC
acetazolamide; systemic
10.1
62.8
72
74
H33.3
ICD-10 Finland
Retinal breaks without detachment
133.1
60.3
64
5
H35.37
ICD-10 Finland
Macular holes
599.0
59.1
58
*
XCK00
NOMESCO Finland
Perimetry
4.5
51.7
133
316
H35.9
ICD-10 Finland
Retinal disorder, unspecified
84.4
51.2
57
7
H35.8
ICD-10 Finland
Other specified retinal disorders
175.3
49.1
51
*
H53.9
ICD-10 Finland
Visual disturbance, unspecified
5.0
47.7
106
223
H53.1
ICD-10 Finland
Subjective visual disturbances
3.6
44.7
158
472
CKW99
NOMESCO Finland
Other operation on choroid, vitreous body and retina
449.5
44.4
44
*
Z96.1
ICD-10 Finland
Presence of intraocular lens
3.0
41.2
203
741
CKD10
NOMESCO Finland
Insufflation of vitreous cavity
+∞
40.8
39
*
XCD10
NOMESCO Finland
Electrophysiological examination of eye
7.1
40.0
61
89
1LA05, ,
NOMESCO Finland
+∞
39.7
38
*
Z3229
NOMESCO Finland
Other healthcare associate professional
3.1
39.1
178
621
CKD40
NOMESCO Finland
Endophotocoagulation of retina
+∞
38.7
37
*
CKD70
NOMESCO Finland
Excision of preretinal or epiretinal membrane
+∞
34.5
33
*
XCW10
NOMESCO Finland
Assessment of vision
10.2
33.7
38
38
S01BC05
ATC
ketorolac; ophthalmic
4.5
33.0
82
189
H33.1
ICD-10 Finland
Retinoschisis and retinal cysts
+∞
32.4
31
*
H34.8
ICD-10 Finland
Other retinal vascular occlusions
71.3
31.0
35
5
H33.2
ICD-10 Finland
Serous retinal detachment
+∞
30.3
29
*
H33.5
ICD-10 Finland
Other retinal detachments
40.9
29.0
36
9
CKD94
NOMESCO Finland
Combined vitrectomy and procedure on lens through pars plana
67.2
29.0
33
5
H35.36
ICD-10 Finland
Macular cyst
297.0
28.9
29
*
CKD91
NOMESCO Finland
Extended vitrectomy through pars plana
79.1
27.8
31
*
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.9
26.3
383
2218
H25.1
ICD-10 Finland
Senile nuclear cataract
2.0
26.2
335
1855
H35.0
ICD-10 Finland
Background retinopathy and retinal vascular changes
73.9
25.8
29
*
Z3231
NOMESCO Finland
Registered nurse
1.8
24.4
446
2772
H43.8
ICD-10 Finland
Other disorders of vitreous body
2.5
24.3
159
667
ZX120
NOMESCO Finland
Intravenous
2.4
23.7
173
763
ZXA05
NOMESCO Finland
Left side
1.9
23.7
396
2390
H26.4
ICD-10 Finland
After-cataract
2.8
23.5
124
467
L04AA01
ATC
[U] ciclosporin
6.1
23.0
40
67
H35.6
ICD-10 Finland
Retinal haemorrhage
+∞
23.0
22
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.7
21.8
615
4298
CKD92
NOMESCO Finland
Combined vitrectomy and retinal procedure
222.9
21.6
22
*
CJB10
NOMESCO Finland
Laser discission of secondary cataract
2.9
21.4
103
369
H43.1
ICD-10 Finland
Vitreous haemorrhage
7.6
21.3
30
40
CK2M4
NOMESCO Finland
Macular light layer imaging (OCT)
24.6
20.9
29
12
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
6.8
20.4
32
48
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
18.6
20.4
31
17
CM2S4
NOMESCO Finland
Follow-up photography of age-related macular degeneration lesions
48.7
20.2
24
5
CKD20
NOMESCO Finland
Removal of vitreous body substitute
+∞
19.8
19
*
F05
ICPC
Visual disturbance other
3.7
19.0
61
170
L04AX01
ATC
azathioprine; systemic
3.0
19.0
85
292
Z94.0
ICD-10 Finland
Kidney transplant status
5.8
17.6
32
56
S01ED51
ATC
timolol, combinations; ophthalmic
2.6
17.5
104
416
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.7
17.2
449
3036
L04AD01
ATC
ciclosporin; systemic
4.4
17.2
43
100
L04AA06
ATC
mycophenolic acid; systemic
4.0
16.8
47
119
TCK00
NOMESCO Finland
Photosensitisation of choroid and retina
+∞
16.7
16
*
CKD15
NOMESCO Finland
Injection of vitreous substitute
+∞
16.7
16
*
CK2L4
NOMESCO Finland
Wide-field/panoramic imaging of ocular fundus
15.2
16.7
27
18
H35.4
ICD-10 Finland
Peripheral retinal degeneration
40.5
16.3
20
5
ZXA00
NOMESCO Finland
Right side
1.7
15.9
400
2672
D31.3
ICD-10 Finland
Benign neoplasm: Choroid
4.6
14.7
35
78
WX100
NOMESCO Finland
Conjunctival surface anesthesia
2.1
14.6
152
773
127
Kela drug reimbursment
Transplant complication
4.1
14.3
39
97
H20.1
ICD-10 Finland
Chronic iridocyclitis
6.5
13.7
22
34
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
3.1
13.6
56
184
H40.0
ICD-10 Finland
Glaucoma suspect
2.2
13.4
114
536
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
5.8
13.2
24
42
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
5.3
13.0
26
50
Z2221
NOMESCO Finland
Medical doctor
1.6
12.9
387
2681
H26.2
ICD-10 Finland
Complicated cataract
5.8
12.7
23
40
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.4
12.2
82
348
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
3.4
11.8
41
121
CK2A4
NOMESCO Finland
Autofluorescence imaging of ocular fundus
30.3
11.6
15
5
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
3.5
11.6
39
113
H02AB04
ATC
methylprednisolone; systemic
1.7
11.3
208
1270
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
3.4
11.1
39
116
H53.4
ICD-10 Finland
Visual field defects
3.5
10.4
36
106
CKD93
NOMESCO Finland
Extended combined procedure on vitreous body and retina
110.7
10.4
11
*
CA1ME
NOMESCO Finland
Ultrasound oculometry
10.7
10.3
19
18
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.5
10.3
420
3091
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
5.3
10.1
20
38
C08CA01
ATC
amlodipine; oral
1.4
10.1
555
4320
S01ED01
ATC
timolol; ophthalmic
2.9
10.0
45
156
A02BC02
ATC
pantoprazole; systemic
1.4
10.0
1030
8931
A12AA04
ATC
calcium carbonate; oral
3.9
10.0
29
76
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
7.4
9.7
22
30
K85
ICPC
Elevated blood pressure
1.6
9.7
221
1427
H02AB06
ATC
prednisolone; systemic
1.4
9.6
694
5652
J01MA02
ATC
ciprofloxacin; systemic
1.4
9.4
567
4473
1LA04, ,
NOMESCO Finland
+∞
9.4
9
*
H30.9
ICD-10 Finland
Chorioretinal inflammation, unspecified
+∞
9.4
9
*
H3601, E113,
ICD-10 Finland
+∞
9.4
9
*
H3600, E113,
ICD-10 Finland
+∞
9.4
9
*
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.7
9.2
160
961
B01AB05
ATC
enoxaparin; parenteral
1.4
9.1
434
3278
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.8
9.1
150
887
H25.0
ICD-10 Finland
Senile incipient cataract
2.1
9.1
81
389
H35
ICD-10 Finland
Other retinal disorders
36.9
9.0
11
*
C03DA01
ATC
spironolactone; oral
1.7
9.0
164
999
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
7.5
8.9
20
27
F43
ICPC
Eye, Other diagnostic procedure
3.1
8.7
35
114
A11CC03
ATC
alfacalcidol; systemic
3.0
8.7
38
130
V03AE01
ATC
polystyrene sulfonate; oral
4.2
8.5
22
53
Z49.1
ICD-10 Finland
Extracorporeal dialysis
3.7
8.5
26
71
H3600, E103,
ICD-10 Finland
+∞
8.3
8
*
H35.5
ICD-10 Finland
Hereditary retinal dystrophy
+∞
8.3
8
*
H26.02
ICD-10 Finland
Presenil cataract
2.7
8.3
44
167
A02BC05
ATC
esomeprazole; systemic
1.4
8.2
592
4784
S01EC54
ATC
brinzolamide, combinations; ophthalmic
4.2
8.2
21
50
S01EE01
ATC
latanoprost; ophthalmic
2.2
8.2
70
331
F29
ICPC
Eye symptom/complaint other
1.8
8.2
123
708
114
Kela drug reimbursment
Glaucoma
1.9
8.2
97
518
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
4.4
8.2
20
46
H02AB09
ATC
hydrocortisone; systemic
2.8
8.1
39
141
N02BE01
ATC
paracetamol; systemic, rectal
1.5
8.1
1377
12756
N18.0
ICD-10 Finland
End-stage renal disease
4.2
8.0
21
51
H57.9
ICD-10 Finland
Disorder of eye and adnexa, unspecified
4.7
7.9
18
39
WX002
NOMESCO Finland
Sedation and analgesia
1.5
7.8
257
1801
P01AB01
ATC
metronidazole; oral, rectal
1.4
7.7
533
4271
TK800
NOMESCO Finland
Hemodialysis
2.7
7.6
39
146
H34.2
ICD-10 Finland
Other retinal artery occlusions
80.5
7.4
8
*
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
2.7
7.4
37
137
H3601, E103,
ICD-10 Finland
+∞
7.3
7
*
XCH05
NOMESCO Finland
Eye pressure longterm registration
5.8
7.2
19
33
XQ848
NOMESCO Finland
Dermatological photography
2.5
7.2
43
174
SPAT1211
SPAT
Application of soft bandage
1.8
7.2
110
638
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
6.6
7.1
17
26
R51.80
ICD-10 Finland
Headache
1.6
7.1
195
1313
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
8.0
7.1
15
19
I10
ICD-10 Finland
Essential (primary) hypertension
1.3
7.1
876
7617
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
2.2
7.1
55
251
J01DB01
ATC
cefalexin; oral
1.4
6.9
1270
11685
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
6.8
471
3763
C69.32
ICD-10 Finland
Malignant tumor of the chorioidea melanoma
40.2
6.8
8
*
TCG40
NOMESCO Finland
Measurement of higher-grade errors of refraction
16.8
6.7
10
6
H36.00
ICD-10 Finland
Diabetic background retinopathy
16.8
6.7
10
6
205
Kela drug reimbursment
Chronic hypertension
1.4
6.6
327
2471
UJF32
NOMESCO Finland
Coloscopy
1.4
6.6
352
2696
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.4
6.6
392
3056
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
1.7
6.5
125
771
D07AC01
ATC
betamethasone; topical
1.3
6.5
495
4007
ZXC15
NOMESCO Finland
Use of photodynamic technique
3.5
6.4
21
60
L04AD02
ATC
tacrolimus; systemic
3.4
6.4
22
65
S01EE04
ATC
travoprost; ophthalmic
3.1
6.4
26
86
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.5
6.3
220
1559
H34.1
ICD-10 Finland
Central retinal artery occlusion
+∞
6.3
6
*
CKD99
NOMESCO Finland
Other intraoclular operations on vitreous body and retina
+∞
6.3
6
*
H57.1
ICD-10 Finland
Ocular pain
2.2
6.2
51
238
137
Kela drug reimbursment
Uraemia requiring dialysis
5.4
6.2
17
32
CS494
NOMESCO Finland
Other visual field testing
2.6
6.2
33
127
L04AX03
ATC
methotrexate; systemic
1.6
6.1
135
864
WX408
NOMESCO Finland
General anesthesy, balanced
1.4
6.0
357
2774
M01AH05
ATC
etoricoxib; oral
1.3
6.0
964
8593
R01AD08
ATC
fluticasone; nasal
1.4
6.0
394
3111
H04.10
ICD-10 Finland
Dry eye syndrome
1.6
6.0
139
900
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1192
10267
1.59
15.11
9.5
7.6
78.34
77.01
u/l
0.40
1126
9752
1523
14052
2.18
15.04
18.9
15.4
3.98
3.98
mmol/l
0.02
1487
13734
30
59
5.16
14.60
26.0
25.3
104.59
125.16
ug/l
0.99
24
45
1515
13996
2.08
14.17
18.7
15.3
139.76
139.72
mmol/l
0.20
1479
13690
1471
13512
1.86
13.14
17.0
13.5
23.31
24.08
mg/l
0.35
1176
10610
1128
9751
1.50
12.64
4.9
3.9
12.33
11.14
mm/h
1.79
1053
9103
787
6359
1.46
12.37
8.0
6.2
27.54
28.09
%
0.76
743
5997
777
6275
1.45
12.18
7.6
6.0
57.08
56.93
%
0.13
734
5911
916
7636
1.45
12.09
10.3
9.3
4.16
4.08
e9/l
0.43
812
6721
1600
15309
2.85
10.56
25.1
19.7
138.08
139.05
g/l
1.72
1579
15118
1554
14697
2.09
10.38
13.0
10.0
28.77
29.21
u/l
0.43
1510
14271
1599
15304
2.79
10.37
25.0
19.6
6.73
6.65
e9/l
0.89
1562
14918
763
6262
1.41
10.32
9.7
6.9
1.21
1.21
mmol/l
0.54
669
5351
644
5132
1.42
10.31
3.5
2.7
174.35
156.17
ug/l
0.48
597
4763
1599
15308
2.78
10.28
25.0
19.6
4.56
4.59
e12/l
1.81
1559
14924
1598
15297
2.74
10.22
25.0
19.6
246.60
246.21
e9/l
0.09
1563
14948
1597
15285
2.71
10.17
25.1
19.7
40.95
41.11
%
0.44
1493
14353
1110
9761
1.42
9.85
3.9
3.6
14.72
14.76
pmol/l
0.20
1024
8961
500
3853
1.43
9.47
4.0
3.1
594.92
296.66
mg/l
0.56
339
2510
628
5040
1.40
9.42
2.1
1.9
96.68
94.94
pmol/l
0.40
343
2726
277
1911
1.54
9.13
3.7
2.5
13.24
13.71
umol/l
0.55
260
1796
814
6848
1.37
9.05
7.3
6.5
11.53
11.67
umol/l
0.11
764
6549
1318
12036
1.48
9.01
4.7
4.2
1.84
2.00
mu/l
0.90
1226
11092
517
4047
1.41
8.84
4.5
3.7
11.22
7.59
mg/mmol
0.95
354
2606
523
4120
1.40
8.57
3.1
2.6
60.53
60.33
u/l
0.02
482
3838
694
5729
1.37
8.51
8.6
6.3
1.21
1.21
mmol/l
0.40
653
5262
938
8118
1.36
8.48
4.8
4.0
50.82
1997.61
e6/l
1.67
11
119
62
279
2.27
8.18
7.4
6.8
904.25
984.74
iu/ml
0.04
12
46
241
1660
1.53
7.94
4.1
2.6
22.91
23.92
%
0.59
206
1424
897
7759
1.34
7.87
5.9
4.9
6.78
6.68
mmol/l
0.82
846
7323
1492
14092
1.65
7.79
5.3
4.7
2.79
2.82
mmol/l
0.68
1395
13178
1281
11733
1.42
7.74
19.5
16.1
15.22
15.18
%
0.03
1263
11518
516
4113
1.37
7.70
3.8
3.1
8.12
8.29
mmol/l
0.35
457
3500
383
2946
1.39
7.01
2.7
2.1
2.82
2.95
mg/l
0.46
325
2491
248
1772
1.47
6.81
3.9
2.5
2.29
2.32
g/l
0.39
235
1653
713
6047
1.32
6.80
3.0
2.5
—
—
—
0
0
1388
12980
1.45
6.77
14.7
12.4
81.10
83.12
ml/min/173m2
2.84
1180
10768
1467
13883
1.54
6.62
4.8
4.3
4.69
4.70
mmol/l
0.14
1373
13053
490
3964
1.34
6.42
2.3
2.2
157.38
289.73
u/l
2.58
466
3749
455
3646
1.34
6.35
1.8
1.7
1.42
1.46
mmol/l
0.34
392
3115
606
5074
1.31
6.17
2.5
2.2
76.75
75.78
nmol/l
0.38
557
4615
1458
13815
1.50
6.16
4.8
4.3
1.41
1.41
mmol/l
0.03
1364
12931
461
3716
1.33
6.15
3.2
2.6
1802.44
5117.99
umol/l
2.04
415
3311
34
135
2.55
5.97
1.4
1.3
—
—
—
0
0
707
6064
1.29
5.94
17.4
13.7
1.27
1.25
inr
0.29
185
1731
728
6272
1.29
5.89
4.2
3.3
0.00
0.00
estimate
0.50
141
1257
74
405
1.87
5.85
1.6
1.3
—
—
—
0
0
1362
12774
1.39
5.81
5.9
5.3
39.59
39.42
mmol/mol
0.31
1283
11970
652
5549
1.29
5.77
6.9
5.0
35.70
35.88
g/l
0.36
622
5206
13
19
6.89
5.74
10.8
8.6
5.12
6.03
mmol/l
0.72
13
19
730
6316
1.28
5.63
4.2
3.3
0.00
0.00
estimate
0.50
129
1131
75
419
1.83
5.58
1.9
1.6
0.63
0.32
iu/ml
0.24
17
72
43
197
2.21
5.53
1.4
1.2
4.20
6.21
u/ml
0.44
15
87
188
1327
1.47
5.47
3.8
2.6
1.77
1.78
%
0.06
172
1189
13
21
6.23
5.38
5.2
5.9
—
—
—
0
0
72
402
1.83
5.37
2.5
1.7
—
—
—
0
0
723
6274
1.27
5.36
5.6
4.5
0.00
0.00
estimate
0.50
130
1205
541
4530
1.29
5.33
4.6
3.4
33.32
37.47
u/l
0.56
516
4311
1412
13375
1.40
5.23
4.3
3.9
1.40
1.38
mmol/l
0.44
1309
12454
91
550
1.69
5.19
2.0
1.9
1.47
1.59
g/l
0.51
82
473
196
1413
1.44
5.11
5.4
4.5
236.38
245.66
u/l
0.43
188
1337
167
1171
1.47
5.03
2.8
2.2
367.96
370.71
nmol/l
0.06
157
1081
204
1492
1.42
4.92
2.6
2.9
7.61
8.12
umol/l
0.21
182
1312
123
820
1.54
4.73
1.3
1.3
209.69
254.05
u/ml
0.31
114
751
53
280
1.92
4.72
1.5
1.2
—
—
—
0
0
207
1529
1.40
4.72
3.0
2.4
209.29
144.94
ug/g
0.84
172
1258
268
2069
1.35
4.66
1.5
1.4
—
—
—
0
0
49
254
1.96
4.62
1.5
1.2
1.19
6.65
u/ml
—
8
15
48
248
1.96
4.57
2.2
1.4
111.00
124.97
u/ml
—
9
51
66
379
1.77
4.54
1.4
1.4
6.24
7.17
u/l
0.34
56
310
378
3083
1.29
4.45
3.0
2.3
—
—
—
0
0
409
3377
1.28
4.37
5.0
4.1
91.31
90.51
%
0.25
397
3297
205
1534
1.38
4.33
2.4
2.3
13.30
13.62
nmol/l
0.25
192
1405
166
1198
1.43
4.32
13.7
7.7
10.62
9.12
mmol/l
2.11
158
1144
70
417
1.71
4.26
4.8
2.1
94.44
91.77
%
0.41
64
401
49
262
1.90
4.24
1.7
1.2
298.21
272.08
u/ml
0.27
40
165
129
890
1.49
4.24
2.4
1.6
—
—
—
0
0
1402
13357
1.34
4.22
4.8
4.4
5.93
5.95
mmol/l
0.22
1288
12365
942
8566
1.23
4.20
3.0
2.8
—
—
—
0
0
160
1156
1.43
4.14
6.6
3.7
5.83
5.89
kpa
0.40
154
1122
64
375
1.74
4.13
1.4
1.4
—
—
—
0
0
19
68
2.82
4.12
1.8
1.5
1.74
1.80
u/field
0.03
14
50
125
863
1.49
4.10
6.8
4.0
131.29
85.23
ng/l
2.36
115
769
44
230
1.94
4.08
1.2
1.1
4.50
1.98
u/ml
0.32
27
121
50
273
1.86
4.08
1.6
1.7
—
—
—
0
0
33
156
2.14
4.01
1.1
1.4
247.04
362.62
pmol/l
1.39
28
145
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
69
418
1.68
3.97
6.3
2.8
0.36
0.34
u/ml
0.16
44
232
455
3850
1.25
3.90
4.0
3.2
28.32
78.22
e6/l
1.79
365
2978
326
2652
1.29
3.88
3.2
2.5
4.31
4.82
e6/l
0.28
294
2413
58
339
1.74
3.80
1.5
1.2
27.94
1.92
u/ml
—
5
12
143
1031
1.42
3.76
2.6
2.7
10.55
10.52
g/l
0.02
129
948
40
209
1.94
3.74
1.2
1.1
—
—
—
0
0
338
2776
1.27
3.72
1.7
1.5
20.14
20.52
nmol/l
0.17
294
2398
55
319
1.75
3.71
1.5
1.2
6.41
12.38
u/ml
0.45
13
44
273
2183
1.30
3.70
3.2
2.7
0.93
0.98
e6/l
0.11
182
1233
324
2651
1.28
3.67
1.3
1.2
1.61
1.83
u/ml
0.09
94
731
62
375
1.68
3.61
1.4
1.5
242.08
284.28
ug/g
1.01
38
214
54
315
1.74
3.58
1.5
1.2
2.28
2.64
u/ml
—
9
24
156
1156
1.39
3.52
6.9
3.7
1.40
2.18
mmol/l
2.16
129
958
417
3531
1.24
3.51
3.8
3.1
0.29
0.41
e6/l
1.09
340
2687
140
1020
1.41
3.49
3.0
2.8
67.03
66.94
g/l
0.06
129
943
29
139
2.11
3.44
1.5
1.2
28561.26
90163.71
e6/l
0.61
19
96
39
209
1.89
3.41
1.4
1.2
4.33
3.10
u/ml
0.26
12
72
256
2052
1.29
3.40
4.0
2.1
29.20
29.76
s
0.95
248
1991
216
1692
1.32
3.40
12.8
6.1
1.08
1.02
mmol/l
1.93
207
1569
55
328
1.70
3.39
1.8
1.6
24191.07
13483.11
e6/l
0.74
41
245
37
196
1.91
3.35
1.1
1.1
0.43
1.90
u/ml
2.33
17
93
162
1222
1.36
3.29
2.5
2.5
37.66
82.14
u/l
0.61
143
1081
1031
9589
1.20
3.21
3.7
3.2
62.44
53.30
u/l
1.11
969
9045
415
3545
1.23
3.19
2.9
3.0
1088.42
1102.25
ng/l
0.03
355
2981
78
517
1.53
3.16
5.5
3.7
24.34
25.01
mmol/l
1.17
73
483
13
44
2.97
3.14
1.2
1.0
—
—
—
0
0
47
275
1.73
3.12
1.7
1.5
—
—
—
0
0
258
2095
1.27
3.10
1.4
1.3
8.80
11.03
u/ml
0.26
115
848
145
1088
1.36
3.06
2.8
2.6
67.22
69.19
ml/min/173m2
0.18
49
409
31
160
1.96
3.05
1.1
1.1
2.66
4.92
u/ml
0.63
13
60
264
2156
1.27
3.02
5.0
3.7
0.83
0.82
mmol/l
0.64
254
2040
348
2933
1.24
3.02
2.3
1.7
1.50
1.11
mg/l
0.59
266
2233
27
133
2.05
3.02
2.8
2.3
—
—
—
0
0
479
4174
1.21
2.99
4.1
3.3
2.35
2.35
mmol/l
0.20
432
3720
568
5029
1.20
2.99
3.5
3.5
41.34
54.50
ng/l
0.40
402
3420
683
6148
1.19
2.99
4.6
4.3
2.18
2.09
ug/l
0.29
625
5593
122
894
1.39
2.97
2.5
2.4
21.28
22.23
au/ml
0.05
11
70
37
206
1.81
2.92
1.1
1.1
4.61
5.87
u/ml
0.20
24
103
290
2405
1.25
2.91
1.6
1.5
2.48
2.53
g/l
0.22
179
1518
36
199
1.83
2.91
1.2
1.1
115.97
115.14
%
0.05
31
182
60
383
1.59
2.89
1.4
1.7
—
—
—
0
0
263
2166
1.26
2.81
1.8
1.7
1145.61
1175.97
nmol/l
0.18
213
1654
205
1639
1.29
2.79
7.4
6.4
—
—
—
0
0
393
3381
1.21
2.78
4.8
3.6
0.00
0.01
estimate
1.08
128
1148
5
6
8.35
2.75
1.6
1.3
—
—
—
0
0
555
4936
1.19
2.73
4.3
3.4
—
—
—
0
0
107
779
1.40
2.73
5.3
3.0
132.03
131.34
g/l
0.10
102
764
265
2192
1.25
2.72
1.4
1.3
30.17
32.21
iu/ml
0.11
92
718
244
2004
1.26
2.67
2.1
1.9
—
—
—
0
0
19
86
2.22
2.64
1.1
1.1
0.98
1.12
u/l
1.02
11
47
47
290
1.64
2.62
1.4
1.8
3.98
5.22
iu/l
0.29
17
94
21
100
2.11
2.59
1.0
1.0
—
—
—
0
0
127
960
1.35
2.59
5.5
2.8
5.37
4.65
kpa
1.40
121
931
5
7
7.16
2.55
1.8
1.3
25.00
24.71
mg/l
—
5
7
68
461
1.50
2.54
1.4
1.2
0.76
0.92
u/ml
—
9
37
17
75
2.28
2.51
1.5
1.4
—
—
—
0
0
551
4942
1.17
2.40
3.9
3.7
22.35
21.26
%
1.02
270
2148
5
8
6.26
2.37
4.4
7.0
—
—
—
0
0
59
396
1.51
2.33
4.7
2.9
1.57
1.49
mg/l
0.32
54
370
175
1406
1.27
2.32
1.8
1.8
—
—
—
0
0
243
2028
1.23
2.31
3.5
2.9
1.75
1.78
e6/l
0.02
151
1085
53
349
1.54
2.29
1.4
1.2
—
—
—
0
0
19
92
2.08
2.27
1.3
1.1
—
—
—
0
0
19
92
2.08
2.27
1.3
1.1
—
—
—
0
0
19
92
2.08
2.27
1.3
1.1
—
—
—
0
0
88
642
1.39
2.26
1.8
1.9
36.91
37.94
nmol/l
0.24
88
619
30
171
1.77
2.25
1.1
1.1
2.34
3.13
u/ml
0.24
17
77
77
553
1.41
2.18
7.1
5.5
1.77
1.68
%
0.30
71
522
104
786
1.35
2.16
5.2
3.4
0.55
1.80
mmol/l
2.45
77
585
54
363
1.50
2.14
1.2
1.1
—
—
—
0
0
54
364
1.50
2.12
1.2
1.1
—
—
—
0
0
175
1423
1.26
2.11
1.9
1.8
—
—
—
0
0
321
2780
1.19
2.09
4.9
3.6
1.02
1.02
kg/l
0.63
46
387
19
96
1.99
2.05
2.2
2.0
0.40
1.68
u/field
—
10
44
13
56
2.33
2.05
1.5
2.1
—
—
—
0
0
13
56
2.33
2.05
1.5
2.1
—
—
—
0
0
25
140
1.80
2.01
1.1
1.0
0.49
0.28
u/ml
—
5
42
9
32
2.82
2.00
1.1
1.0
—
—
—
0
0
28
163
1.73
1.99
1.7
1.5
57.75
62.38
%
0.30
20
101
16
77
2.09
1.97
1.1
1.2
—
—
—
0
0
24
134
1.80
1.95
1.2
1.2
—
—
—
0
0
19
98
1.95
1.95
1.5
1.2
—
—
—
0
0
18
91
1.99
1.95
1.3
1.1
—
—
—
0
0
18
91
1.99
1.95
1.3
1.1
—
—
—
0
0
27
158
1.72
1.89
1.3
1.1
—
—
—
0
0
14
65
2.16
1.88
1.6
1.4
—
—
—
0
0
14
65
2.16
1.88
1.6
1.4
—
—
—
0
0
302
2627
1.18
1.87
1.8
1.7
419.67
37027450.55
pmol/l
2.84
253
2220
9
34
2.66
1.86
1.8
1.5
—
—
—
0
0
62
444
1.41
1.82
1.3
1.3
25.91
27.35
iu/l
0.11
47
372
5
12
4.18
1.82
2.6
1.0
—
—
—
0
0
407
3641
1.16
1.77
2.8
2.7
0.71
0.70
ug/l
0.08
277
2229
61
439
1.40
1.75
2.3
2.6
2.92
2.94
g/l
0.04
56
402
13
61
2.14
1.71
2.2
2.4
—
—
—
0
0
5
13
3.85
1.71
1.0
1.5
138.40
117.92
ng/l
—
5
13
15
75
2.01
1.69
1.5
1.4
—
—
—
0
0
26
156
1.68
1.69
1.1
1.1
—
—
—
0
0
65
477
1.38
1.68
1.8
1.9
196.78
210.94
pmol/l
0.76
60
453
40
268
1.50
1.67
3.2
3.4
4.13
4.22
e9/l
0.11
40
268
10
40
2.51
1.66
1.2
1.3
—
—
—
0
0
23
134
1.73
1.66
1.6
1.4
23.09
29.42
%
0.53
15
85
8
31
2.59
1.66
2.0
1.6
1499.52
113.23
nmol/24h
—
8
31
7
25
2.81
1.65
1.0
1.2
—
—
—
0
0
236
2036
1.19
1.62
1.8
1.9
1.53
1.47
%
0.29
208
1810
5
14
3.58
1.61
1.8
1.4
—
—
—
0
0
5
14
3.58
1.61
1.2
1.2
—
—
—
0
0
126
1022
1.25
1.60
3.3
2.8
213.70
173.90
ng/l
0.40
113
935
25
151
1.67
1.60
2.0
1.6
—
—
—
0
0
8
32
2.51
1.59
1.8
1.3
—
—
—
0
0
6
20
3.01
1.58
1.2
1.3
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
15
78
1.93
1.54
1.1
1.1
—
—
—
0
0
57
417
1.38
1.52
1.7
1.8
—
—
—
0
0
7
27
2.60
1.51
1.0
1.1
—
—
—
0
0
75
574
1.32
1.51
1.1
1.0
—
—
—
0
0
44
308
1.44
1.50
1.2
1.3
1544.77
1062.23
e6/l
0.12
35
243
44
308
1.44
1.50
1.2
1.3
270.79
40.14
e6/l
0.40
33
237
6
21
2.86
1.50
1.3
1.2
—
—
—
0
0
18
101
1.79
1.49
6.4
5.7
64.28
58.41
u/ml
—
9
30
20
116
1.73
1.49
1.4
1.3
—
—
—
0
0
40
276
1.46
1.48
3.5
3.6
56.98
57.06
%
0.02
40
276
38
260
1.47
1.46
1.7
1.7
—
—
—
0
0
95
755
1.27
1.45
1.2
1.2
119.90
153.24
iu/ml
0.48
34
292
24
148
1.63
1.44
2.0
1.6
—
—
—
0
0
27
172
1.58
1.43
1.3
1.4
0.64
0.65
nmol/l
0.06
27
165
17
95
1.80
1.43
1.2
1.2
—
—
—
0
0
17
95
1.80
1.43
1.2
1.2
—
—
—
0
0
19
110
1.74
1.43
2.6
1.9
19.84
18.60
nmol/l
0.20
19
101
187
1601
1.19
1.42
5.0
4.3
31.38
31.17
%
0.10
141
1125
26
165
1.59
1.40
1.1
1.1
—
—
—
0
0
24
150
1.61
1.38
2.0
1.6
—
—
—
0
0
24
150
1.61
1.38
2.0
1.6
—
—
—
0
0
5
120
0.41
1.37
29.2
18.2
1541.40
1508.77
nmol/l
—
5
120
6
23
2.61
1.37
1.5
1.8
—
—
—
0
0
24
151
1.60
1.35
2.0
1.6
—
—
—
0
0
24
151
1.60
1.35
2.0
1.6
—
—
—
0
0
13
68
1.92
1.33
2.5
2.8
737.23
901.85
u/ml
0.35
13
68
61
464
1.33
1.31
2.3
2.5
3.68
3.68
g/l
0.01
56
428
146
1233
1.20
1.30
2.5
2.3
0.22
0.22
g/l
0.15
141
1151
61
465
1.32
1.29
2.3
2.5
7.34
7.33
g/l
0.02
56
428
61
465
1.32
1.29
2.3
2.5
—
—
—
0
0
10
48
2.09
1.27
1.0
1.1
—
—
—
0
0
23
147
1.57
1.23
1.3
2.1
49.80
22.12
mg/l
—
5
36
58
443
1.32
1.23
2.3
3.0
—
—
—
0
0
8
37
2.17
1.21
1.1
1.3
120.63
107.93
%
—
8
30
37
263
1.42
1.21
1.3
1.3
—
—
—
0
0
37
263
1.42
1.21
1.3
1.3
—
—
—
0
0
8
38
2.11
1.18
1.1
2.9
—
—
—
0
0
57
437
1.32
1.18
2.4
2.6
11.01
10.41
g/l
0.46
52
399
10
50
2.01
1.16
1.3
1.1
—
—
—
0
0
137
1165
1.19
1.16
2.0
2.3
7.48
7.91
ug/l
0.11
114
1053
13
72
1.81
1.15
1.1
1.1
—
—
—
0
0
8
40
2.00
1.12
1.1
1.1
—
—
—
0
0
74
593
1.26
1.11
4.4
3.2
25.37
25.38
mmol/l
0.01
69
575
5
22
2.28
1.03
1.2
1.9
—
—
—
0
0
5
22
2.28
1.03
3.4
1.4
1.20
1.19
mmol/l
—
5
22
61
485
1.27
1.00
1.0
1.1
—
0.82
—
0
9
278
2524
1.12
0.99
4.2
3.7
302.43
557.35
ng/l
0.70
225
1973
43
327
1.32
0.98
1.4
1.2
—
—
—
0
0
55
433
1.28
0.98
1.7
1.8
—
—
—
0
0
9
50
1.80
0.96
4.9
2.8
—
—
—
0
0
74
608
1.23
0.93
1.3
1.3
—
—
—
0
0
12
70
1.72
0.92
1.0
1.2
—
—
—
0
0
37
278
1.34
0.92
2.7
2.2
137.79
130.51
g/l
1.17
29
200
9
52
1.73
0.92
1.7
1.1
1369.56
1538.21
miu/ml
—
9
52
129
1119
1.17
0.90
1.8
1.8
—
—
—
0
0
177
1576
1.14
0.87
8.6
8.3
0.91
1.18
mmol/l
0.51
149
1267
48
378
1.28
0.87
2.5
3.8
1.78
1.25
ratio
—
5
34
6
30
2.00
0.87
1.0
1.4
—
—
—
0
0
25
345
0.72
0.86
1.4
1.3
156.75
212.99
miu/ml
—
8
148
6
31
1.94
0.84
1.0
1.1
61.70
44.11
u/ml
—
6
31
49
390
1.26
0.83
2.4
3.7
30.44
56.06
mg/l
0.90
41
308
49
390
1.26
0.83
2.4
3.7
48.89
68.17
mg/l
0.52
41
309
244
2226
1.11
0.81
3.2
3.0
2.43
2.45
mmol/l
0.88
222
1966
20
138
1.45
0.81
5.3
2.5
—
—
—
0
0
51
410
1.25
0.80
2.5
2.8
0.60
1.17
g/l
0.86
45
369
6
33
1.82
0.79
1.0
1.1
—
—
—
0
0
11
66
1.67
0.78
1.3
1.5
—
—
—
0
0
44
349
1.27
0.77
1.5
1.3
—
—
—
0
0
6
34
1.77
0.76
1.0
1.1
—
—
—
0
0
101
875
1.16
0.75
9.2
10.6
0.66
0.68
%
0.31
101
869
11
67
1.65
0.75
1.1
1.4
—
248.33
—
0
6
86
736
1.18
0.74
1.8
1.6
—
—
—
0
0
7
39
1.80
0.72
1.1
1.1
—
—
—
0
0
7
39
1.80
0.72
1.3
1.1
—
—
—
0
0
20
142
1.41
0.72
1.3
1.0
—
—
—
0
0
9
56
1.61
0.72
1.0
1.2
—
—
—
0
0
6
109
0.55
0.72
2.7
1.8
—
—
—
0
0
7
40
1.75
0.71
1.3
1.1
—
—
—
0
0
44
354
1.25
0.71
1.7
1.8
—
—
—
0
0
20
143
1.40
0.70
1.1
1.0
—
—
—
0
0
14
93
1.51
0.69
1.0
1.0
—
—
—
0
0
153
1375
1.12
0.69
1.5
1.4
—
—
—
0
0
85
733
1.17
0.68
1.6
1.4
—
—
—
0
0
7
42
1.67
0.68
1.3
1.1
—
—
—
0
0
42
339
1.25
0.66
1.2
1.1
—
—
—
0
0
14
94
1.49
0.66
1.1
1.0
193.67
251.92
ng/l
—
9
60
13
86
1.52
0.66
2.3
1.5
—
—
—
0
0
35
277
1.27
0.65
3.8
2.8
8.73
7.99
kpa
1.95
35
272
100
879
1.15
0.64
9.3
10.7
94.77
93.86
%
2.07
100
874
14
95
1.48
0.64
1.1
1.0
739.86
746.10
ng/l
—
7
58
14
95
1.48
0.64
1.1
1.0
32.29
38.60
ng/l
—
7
58
46
378
1.22
0.63
2.0
2.6
37.47
38.06
g/l
0.29
41
341
25
190
1.32
0.63
1.5
1.4
166.58
214.78
pmol/l
0.47
25
190
8
49
1.64
0.62
5.4
2.9
—
—
—
0
0
8
49
1.64
0.62
5.4
2.9
—
—
—
0
0
38
307
1.24
0.61
1.5
1.5
—
—
—
0
0
19
139
1.37
0.60
3.3
2.0
—
—
—
0
0
60
510
1.18
0.59
1.5
1.8
—
—
—
0
0
8
53
1.51
0.58
5.0
3.1
—
—
—
0
0
19
253
0.75
0.57
1.1
1.1
—
—
—
0
0
18
132
1.37
0.57
2.4
1.7
—
—
—
0
0
14
195
0.72
0.56
1.2
1.1
—
—
—
0
0
25
194
1.29
0.56
1.4
1.5
—
—
—
0
0
20
150
1.34
0.56
3.2
2.0
—
—
—
0
0
57
486
1.18
0.55
2.6
2.0
—
—
—
0
0
6
37
1.62
0.55
1.3
1.6
15.83
17.20
pmol/l
—
6
30
11
159
0.69
0.54
1.9
2.0
—
—
—
0
0
36
295
1.23
0.53
2.2
2.1
321.46
132.28
ug/min
0.34
21
180
9
62
1.45
0.53
4.9
2.5
—
—
—
0
0
9
62
1.45
0.53
4.9
2.5
—
—
—
0
0
13
91
1.43
0.53
3.8
2.7
0.27
0.22
e9/l
0.42
13
82
16
117
1.37
0.52
3.5
2.0
—
—
—
0
0
16
117
1.37
0.52
3.5
2.0
—
—
—
0
0
16
117
1.37
0.52
3.5
2.0
—
—
—
0
0
146
1336
1.10
0.51
3.6
3.4
—
—
—
0
0
6
41
1.47
0.50
1.3
1.3
—
—
—
0
0
23
180
1.28
0.49
1.1
1.1
—
—
—
0
0
24
189
1.27
0.49
1.1
1.0
4.21
2.41
u/ml
0.39
11
87
7
48
1.46
0.46
3.7
1.4
8.74
8.84
ug/l
—
7
48
40
337
1.19
0.46
1.2
1.1
3.32
5.93
u/ml
—
6
42
23
182
1.27
0.46
1.6
1.6
—
—
—
0
0
7
49
1.43
0.46
1.9
2.1
—
—
—
0
0
51
441
1.16
0.45
1.9
1.7
—
—
—
0
0
15
112
1.34
0.44
1.0
1.3
0.05
0.84
u/ml
—
6
63
29
238
1.22
0.44
1.5
1.7
—
—
—
0
0
16
208
0.77
0.44
2.4
2.0
1.40
1.64
mmol/l
0.62
16
203
5
31
1.61
0.43
1.2
1.3
—
—
—
0
0
36
304
1.19
0.42
1.3
1.4
—
—
—
0
0
10
70
1.43
0.41
2.5
3.6
—
—
—
0
0
13
96
1.36
0.41
2.6
2.9
40.67
39.50
%
—
7
48
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
23
282
0.81
0.40
2.9
2.5
17.57
16.36
%
0.78
15
146
7
106
0.66
0.39
1.6
1.3
1.42
1.53
g/l
—
7
106
15
116
1.30
0.37
1.7
2.0
—
—
—
0
0
109
1004
1.09
0.37
1.7
1.7
—
—
—
0
0
25
208
1.21
0.35
1.6
1.6
—
—
—
0
0
6
43
1.40
0.35
1.7
2.0
95.37
50.93
ug/l
—
6
43
138
1288
1.08
0.35
3.9
4.3
7.21
17.20
ug/l
1.28
108
1050
15
118
1.27
0.33
1.2
1.5
—
—
—
0
0
12
92
1.31
0.32
1.7
2.1
—
—
—
0
0
26
221
1.18
0.30
1.1
1.1
1.59
1.48
g/l
0.68
26
199
17
138
1.23
0.30
1.2
1.4
—
—
—
0
0
10
129
0.77
0.28
1.6
1.5
0.94
1.00
g/l
—
10
129
8
62
1.29
0.28
2.8
1.9
14.29
1.52
nmol/l
—
8
53
21
178
1.18
0.26
1.4
1.3
8.74
7.31
mmol/l
0.45
15
156
26
225
1.16
0.26
2.6
2.0
—
—
—
0
0
26
225
1.16
0.26
2.6
2.0
—
—
—
0
0
157
1495
1.06
0.24
1.8
1.8
—
—
—
0
0
0
11
0.00
0.21
0.0
2.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
12
98
1.23
0.21
1.3
1.2
—
—
—
0
0
19
218
0.87
0.19
3.4
2.8
0.68
0.77
nmol/l
0.64
14
170
6
51
1.18
0.19
1.0
1.0
—
—
—
0
0
24
270
0.89
0.19
3.3
3.3
33.88
26.69
mg/l
0.35
17
162
6
52
1.15
0.19
1.0
2.3
1.26
0.97
ug/l
—
6
47
7
58
1.21
0.18
1.0
1.5
—
—
—
0
0
7
62
1.13
0.17
1.1
1.1
97.61
210.45
iu/ml
—
7
62
15
129
1.16
0.17
1.1
1.0
276.73
278.27
mg/l
0.03
15
116
18
204
0.88
0.16
1.8
1.8
—
—
—
0
0
9
78
1.15
0.15
1.2
1.4
12.44
13.30
u/l
—
9
73
53
498
1.07
0.14
4.0
4.2
1.35
1.31
mmol/l
0.12
53
489
25
227
1.10
0.14
1.5
1.4
—
—
—
0
0
13
113
1.15
0.13
1.1
1.1
—
—
—
0
0
12
138
0.87
0.13
1.4
1.5
—
—
—
0
0
11
127
0.87
0.12
1.4
1.2
1.62
1.46
nmol/l
0.30
11
117
11
95
1.16
0.11
1.5
1.5
—
—
—
0
0
30
322
0.93
0.11
2.9
2.0
—
—
—
0
0
20
182
1.10
0.11
1.4
1.2
—
—
—
0
0
11
96
1.15
0.10
1.5
1.9
—
—
—
0
0
14
125
1.12
0.10
1.4
1.5
—
—
—
0
0
6
54
1.11
0.09
1.2
1.8
—
—
—
0
0
12
107
1.12
0.08
1.2
1.5
87.67
82.27
umol/l
0.58
12
107
5
64
0.78
0.08
1.0
1.0
—
—
—
0
0
6
70
0.86
0.07
1.0
1.2
—
—
—
0
0
21
196
1.07
0.07
1.7
1.7
—
—
—
0
0
8
90
0.89
0.06
2.0
1.7
—
—
—
0
0
51
492
1.04
0.06
4.2
2.3
218.00
419.59
ug/l
1.09
45
463
19
178
1.07
0.05
1.1
1.1
—
—
—
0
0
99
1010
0.98
0.05
5.0
4.3
1.22
1.23
mmol/l
0.32
86
899
13
141
0.92
0.05
5.0
4.5
—
—
—
0
0
17
159
1.07
0.05
2.2
2.3
31.53
32.81
pg
0.48
17
159
52
535
0.97
0.05
1.5
1.8
3.52
5.18
mg/l
0.61
35
398
13
120
1.08
0.05
1.3
1.4
—
—
—
0
0
13
120
1.08
0.05
1.3
1.4
—
—
—
0
0
23
241
0.95
0.04
3.3
2.0
—
—
—
0
0
13
121
1.07
0.03
1.3
1.4
—
—
—
0
0
13
121
1.07
0.03
1.3
1.4
—
—
—
0
0
34
330
1.03
0.03
4.3
2.9
23.69
24.84
mmol/l
1.01
34
325
32
329
0.97
0.02
2.6
1.9
—
—
—
0
0
21
203
1.03
0.01
2.4
2.3
13766.83
1698.35
u/l
—
6
68
17
164
1.04
0.00
1.4
1.7
—
—
—
0
0
17
164
1.04
0.00
1.4
1.7
—
—
—
0
0
31
307
1.01
0.00
1.5
1.4
1.00
0.89
nmol/l
0.43
25
267
29
295
0.98
0.00
1.4
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
7.89
—
0
6
0
9
0.00
0.00
0.0
4.4
—
—
—
0
0
0
9
0.00
0.00
0.0
3.8
—
—
—
0
0
7
78
0.90
-0.00
2.0
1.8
—
—
—
0
0
6
61
0.98
-0.00
1.0
1.1
67.42
90.45
u/l
—
6
61
6
61
0.98
-0.00
1.0
1.1
22.33
25.19
u/l
—
6
61
0
5
0.00
-0.00
0.0
1.2
—
8.68
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
36.16
—
0
5
0
5
0.00
-0.00
0.0
15.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
7
78
0.90
-0.00
2.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
94
0.96
-0.00
1.4
1.2
—
—
—
0
0
7
78
0.90
-0.00
1.6
1.6
—
—
—
0
0
6
63
0.95
-0.00
2.3
1.8
—
—
—
0
0
26
260
1.00
-0.00
2.5
3.9
146.87
1176.66
u/ml
0.57
26
246
6
66
0.91
-0.00
1.7
1.6
—
3070600.00
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
1745.20
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
22.82
—
0
5
8
87
0.92
-0.00
10.6
11.1
0.59
0.62
mmol/l
—
8
80
Mortality – FinRegistry
↥Association
Association between endpoint H7_RETINASEPAR and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_RETINASEPAR | 0.841 [0.72, 0.98] | 0.026 |
| Birth year | 0.995 [0.99, 1.0] | 0.238 |
During the follow-up period (1.1.1998 — 31.12.2019), 301 out of 3022 females with H7_RETINASEPAR died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_RETINASEPAR | 0.78 [0.68, 0.89] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.006 |
During the follow-up period (1.1.1998 — 31.12.2019), 454 out of 6289 males with H7_RETINASEPAR died.
Mortality risk
Mortality risk for people of age
years, who have H7_RETINASEPAR.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.074% | 0.139% |
| 5 | 0.577% | 0.861% |
| 10 | 1.373% | 2.266% |
| 15 | 2.356% | 4.337% |
| 20 | 4.263% | 7.317% |
Relationships between endpoints
↥Index endpoint: H7_RETINASEPAR – Separation of retinal layers (serosa)
GWS hits: 3
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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