This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Congenital nasolacrimal duct obstruction or stenosis
Q17_CONGENITAL_NASOLACRIMAL_DUCT_OBSTRUCTION_OR_STENOSIS_WIDE
No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
201 |
4. Check minimum number of eventsNone |
201 |
5. Include endpointsNone |
201 |
6. Filter based on genotype QC (FinnGen only) |
188 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- First used in FinnGen datafreeze
- DF13
Similar endpoints
↥List of similar endpoints to
Congenital nasolacrimal duct obstruction or stenosis
based on the number of shared cases.
Similar with more cases:
- Congenital malformations of eyelid, lacrimal apparatus and orbit
- Congenital malformations, deformations and chromosomal abnormalities
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 188 | 127 | 61 |
| Unadjusted period prevalence (%) | 0.04 | 0.05 | 0.03 |
| Median age at first event (years) | 1.28 | 1.32 | 1.19 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 201
- Matched controls
- 2009
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q10.5
ICD-10 Finland
Congenital stenosis and stricture of lacrimal duct
+∞
290.9
201
*
TCC10
NOMESCO Finland
Probing of lacrimal canaliculus/duct
419.6
99.4
92
*
H04.5
ICD-10 Finland
Stenosis and insufficiency of lacrimal passages
58.5
36.4
42
9
CCA20
NOMESCO Finland
Incision of lacrimal punctum or canaliculus
338.1
29.6
29
*
XCC00
NOMESCO Finland
Investigative irrigation of lacrimal passages
149.6
13.6
14
*
TCC30
NOMESCO Finland
Intubation of lacrimal canaliculus/duct
63.4
10.7
12
*
ZXD10
NOMESCO Finland
Scheduled procedure
2.7
10.2
85
433
ZXE00
NOMESCO Finland
One hour or less
2.4
8.3
92
524
ZXA10
NOMESCO Finland
Bilateral
2.6
7.0
46
204
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
69
510
1.54
2.11
4.5
4.4
—
—
—
0
0
60
440
1.52
1.88
3.8
4.2
0.12
0.29
e6/l
1.20
50
336
32
204
1.68
1.79
2.3
2.4
3722.56
3409.41
u/l
—
10
68
174
1599
1.65
1.64
10.3
11.0
20.97
22.17
mg/l
0.15
125
1136
6
24
2.54
1.31
1.7
1.1
—
—
—
0
0
163
1509
1.42
1.14
7.4
8.0
23.32
24.22
u/l
0.32
158
1448
50
391
1.37
1.09
4.5
6.4
1.05
1.15
inr
1.63
23
133
74
866
0.77
1.00
3.4
3.2
34.65
36.20
mmol/mol
1.12
68
812
5
23
2.20
0.98
1.0
1.0
—
—
—
0
0
36
271
1.40
0.98
3.7
3.9
1.01
1.02
e6/l
0.01
24
158
8
46
1.77
0.83
3.1
4.3
1.50
3.30
e6/l
—
8
30
8
46
1.77
0.83
7.1
23.3
1.20
1.10
%
—
8
46
8
46
1.77
0.83
3.1
4.3
36.63
50.22
e6/l
—
8
32
8
47
1.73
0.81
7.1
22.9
0.74
0.68
%
—
8
47
47
381
1.30
0.81
2.8
2.1
—
—
—
0
0
8
48
1.69
0.79
1.4
1.1
—
—
—
0
0
0
25
0.00
0.79
0.0
1.5
—
—
—
0
0
22
158
1.44
0.78
1.4
1.4
141.26
371.30
u/ml
0.73
16
147
40
319
1.32
0.77
2.8
2.0
—
—
—
0
0
189
1828
1.56
0.73
16.1
15.4
262.53
267.78
e9/l
0.53
184
1759
110
997
1.23
0.72
8.2
9.7
3.76
3.67
e9/l
0.13
98
834
30
232
1.34
0.71
1.4
1.4
—
—
—
0
0
5
26
1.94
0.71
1.0
2.1
—
—
—
0
0
189
1830
1.54
0.70
16.1
15.4
4.60
4.58
e12/l
0.24
181
1761
33
260
1.32
0.70
6.7
9.1
4.65
5.12
kpa
1.26
33
254
0
20
0.00
0.60
0.0
3.9
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
82.75
—
0
20
0
20
0.00
0.60
0.0
3.9
—
—
—
0
0
33
267
1.28
0.58
2.9
2.7
27.67
28.22
ng/l
0.01
15
116
12
81
1.51
0.58
2.8
3.7
1.21
1.23
mmol/l
1.13
12
69
65
571
1.20
0.56
6.2
7.2
22.58
23.13
umol/l
0.03
59
526
33
269
1.27
0.56
7.4
9.2
0.75
0.93
mmol/l
0.13
28
207
12
82
1.49
0.55
6.3
7.7
158.25
174.28
%
0.35
12
82
6
99
0.59
0.53
1.3
1.3
—
—
—
0
0
33
271
1.26
0.53
3.1
4.6
1.00
1.58
mg/l
0.63
20
187
33
271
1.26
0.53
3.8
4.0
5.02
3.03
e6/l
0.31
21
160
33
271
1.26
0.53
7.3
9.1
5.85
5.74
kpa
0.44
33
265
53
459
1.21
0.53
6.3
7.6
38.39
36.92
g/l
1.16
53
434
6
40
1.51
0.52
1.0
1.4
—
—
—
0
0
7
45
1.57
0.49
15.6
5.7
62.17
50.54
%
—
7
45
7
46
1.54
0.49
7.3
23.1
21.57
23.67
mmol/l
—
7
46
14
102
1.40
0.48
5.6
13.9
94.57
85.81
%
0.62
14
102
7
47
1.51
0.48
3.4
12.2
—
182.20
—
0
5
7
48
1.47
0.47
1.4
1.6
—
—
—
0
0
11
78
1.43
0.44
1.1
1.4
—
—
—
0
0
6
91
0.65
0.43
2.5
2.8
4.32
5.07
pmol/l
—
6
80
25
204
1.26
0.43
1.0
1.1
—
—
—
0
0
13
96
1.38
0.42
8.3
3.6
—
—
—
0
0
5
33
1.53
0.41
1.2
1.4
—
—
—
0
0
5
33
1.53
0.41
4.8
3.9
87.60
96.48
%
—
5
33
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
34
290
1.21
0.40
13.4
14.5
24.99
24.46
mmol/l
0.70
34
290
87
805
1.14
0.38
3.6
3.2
64.94
48.58
ug/l
0.51
79
751
168
1627
1.20
0.38
3.8
4.0
—
—
—
0
0
29
246
1.21
0.36
5.3
9.0
23.03
23.19
mmol/l
0.12
29
246
15
189
0.78
0.36
1.8
2.8
320.13
362.37
nmol/l
0.41
15
180
15
117
1.30
0.36
1.5
1.4
259.92
276.78
miu/ml
—
10
60
86
799
1.13
0.35
6.3
6.6
5.84
5.94
mmol/l
0.18
81
723
32
278
1.18
0.32
9.6
10.8
1.36
1.33
mmol/l
0.20
32
266
66
607
1.13
0.31
2.8
3.2
—
—
—
0
0
111
1058
1.11
0.27
2.7
2.7
5.24
5.44
mmol/l
1.70
94
963
22
188
1.19
0.26
1.4
1.3
—
—
—
0
0
125
1200
1.11
0.26
3.3
3.3
14.57
14.49
pmol/l
0.13
112
1067
15
180
0.82
0.25
1.7
1.4
—
—
—
0
0
11
137
0.79
0.25
1.5
2.7
26.91
34.00
u/l
0.58
11
114
75
703
1.11
0.25
6.0
4.8
0.00
0.00
estimate
-0.00
16
157
75
704
1.10
0.24
4.4
3.5
0.00
0.00
estimate
-0.00
16
151
40
362
1.13
0.24
1.8
1.5
89.84
94.40
pmol/l
0.30
23
177
5
37
1.36
0.23
1.0
1.7
0.17
0.19
nmol/l
—
5
32
5
40
1.26
0.22
5.6
3.8
125.40
315.79
ug/l
—
5
34
0
11
0.00
0.21
0.0
1.2
—
146.59
—
0
11
0
10
0.00
0.21
0.0
1.7
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
369.20
—
0
10
0
12
0.00
0.21
0.0
1.6
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
11
89
1.25
0.21
2.0
2.6
—
—
—
0
0
75
709
1.09
0.21
4.3
3.5
0.00
0.00
estimate
-0.00
14
153
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
2.5
—
—
—
0
0
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
6
49
1.23
0.20
1.2
1.5
—
—
—
0
0
6
51
1.18
0.19
1.0
1.5
—
—
—
0
0
6
51
1.18
0.19
1.0
1.5
—
—
—
0
0
55
514
1.10
0.19
4.3
3.3
—
—
—
0
0
27
242
1.13
0.19
12.8
11.2
9.51
9.51
kpa
0.00
27
234
17
195
0.86
0.18
1.5
4.3
566.14
613.85
ng/l
—
7
110
10
121
0.82
0.18
1.4
1.3
—
—
—
0
0
104
1002
1.08
0.18
3.0
3.0
2.60
2.62
mmol/l
0.09
95
944
10
82
1.23
0.17
2.2
1.9
—
—
—
0
0
35
322
1.10
0.17
2.8
3.1
—
—
—
0
0
19
214
0.88
0.17
12.9
10.5
0.80
0.81
mmol/l
0.03
19
202
9
80
1.13
0.15
1.8
1.4
—
—
—
0
0
7
86
0.81
0.15
1.3
1.4
—
—
—
0
0
7
89
0.78
0.15
1.4
1.4
—
—
—
0
0
11
93
1.19
0.15
2.5
1.6
—
—
—
0
0
11
93
1.19
0.15
2.0
1.8
—
—
—
0
0
55
579
0.93
0.14
2.8
2.5
—
—
—
0
0
9
110
0.81
0.13
1.3
2.2
—
—
—
0
0
15
134
1.13
0.11
8.7
9.5
104.27
105.30
mmol/l
0.32
15
134
16
144
1.12
0.10
1.9
2.0
—
—
—
0
0
102
995
1.05
0.10
2.8
2.8
1.43
1.43
mmol/l
0.01
93
941
5
47
1.06
0.09
1.2
3.0
—
—
—
0
0
105
1026
1.05
0.09
3.7
4.0
6.81
8.39
mm/h
1.55
93
954
12
107
1.13
0.08
1.2
1.2
—
—
—
0
0
6
58
1.04
0.08
13.5
12.2
0.88
0.72
%
—
6
58
5
64
0.78
0.08
1.2
1.1
—
13.84
—
0
7
14
127
1.11
0.08
9.4
14.9
1.31
1.34
mmol/l
0.08
14
122
7
68
1.03
0.08
6.1
4.0
23.57
23.71
nmol/l
—
7
68
59
609
0.96
0.08
2.9
2.7
—
—
—
0
0
6
72
0.83
0.08
1.3
1.4
1.12
1.18
g/l
—
6
67
6
74
0.80
0.07
1.5
1.3
—
—
—
0
0
6
74
0.80
0.07
1.5
1.3
—
—
—
0
0
6
74
0.80
0.07
1.5
1.3
—
—
—
0
0
16
147
1.10
0.07
2.0
2.0
—
—
—
0
0
9
84
1.07
0.07
2.0
1.8
—
—
—
0
0
107
1052
1.04
0.06
6.7
7.5
106.59
107.08
ml/min/173m2
0.07
81
755
138
1363
1.04
0.06
3.8
3.9
2.03
1.97
mu/l
0.20
127
1270
76
775
0.97
0.05
1.9
1.9
—
—
—
0
0
28
268
1.05
0.05
12.7
10.9
1.61
1.00
mmol/l
0.51
22
189
103
1017
1.03
0.03
2.9
3.0
4.29
4.37
mmol/l
0.38
94
971
28
270
1.04
0.03
12.7
10.8
5.23
5.04
kpa
0.76
28
263
68
669
1.02
0.03
1.7
1.6
1.76
2.81
u/ml
0.29
12
128
95
939
1.02
0.02
2.7
2.7
1.01
1.12
mmol/l
1.60
86
897
20
201
0.99
0.00
2.0
2.0
—
—
—
0
0
38
380
1.00
0.00
4.8
3.6
0.00
0.00
estimate
-0.00
16
151
16
158
1.01
0.00
2.9
1.9
—
—
—
0
0
0
7
0.00
0.00
0.0
6.6
—
—
—
0
0
0
7
0.00
0.00
0.0
4.9
—
214.14
—
0
7
9
90
1.00
-0.00
2.8
1.7
—
—
—
0
0
7
76
0.92
-0.00
1.0
1.0
7.11
7.52
kpa
—
7
64
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
12.57
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
127.80
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
9.20
—
0
5
7
75
0.93
-0.00
1.3
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
11.30
—
0
6
5
51
0.98
-0.00
1.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
39.17
—
0
6
0
6
0.00
-0.00
0.0
1.2
—
20.83
—
0
6
9
93
0.97
-0.00
1.1
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
55.17
—
0
6
7
76
0.92
-0.00
1.0
1.0
19.43
19.17
mmol/l
—
7
76
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
6.8
—
220.60
—
0
5
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
49
1.02
-0.00
1.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
75
0.93
-0.00
1.0
1.0
2.91
3.20
kpa
—
7
63
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.4
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: Q17_CONGENITAL_NASOLACRIMAL_DUCT_OBSTRUCTION_OR_STENOSIS_WIDE – Congenital nasolacrimal duct obstruction or stenosis
GWS hits: -
This endpoint is excluded (different definition than used in FinnGen).