No definition available.
Congenital nasolacrimal duct obstruction or stenosis
Q17_CONGENITAL_NASOLACRIMAL_DUCT_OBSTRUCTION_OR_STENOSIS
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
181 |
4. Check minimum number of eventsNone |
181 |
5. Include endpointsNone |
181 |
6. Filter based on genotype QC (FinnGen only) |
172 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Similar endpoints
↥List of similar endpoints to
Congenital nasolacrimal duct obstruction or stenosis
based on the number of shared cases.
Similar with more cases:
- Congenital nasolacrimal duct obstruction or stenosis
- Congenital malformations of eyelid, lacrimal apparatus and orbit
- Congenital malformations of eyelid, lacrimal apparatus and orbit
- Congenital malformations of eye, ear, face and neck
- Congenital malformations, deformations and chromosomal abnormalities
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 172 | 116 | 56 |
| Unadjusted period prevalence (%) | 0.04 | 0.04 | 0.03 |
| Median age at first event (years) | 1.28 | 1.31 | 1.21 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 181
- Matched controls
- 1809
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q10.5
ICD-10 Finland
Congenital stenosis and stricture of lacrimal duct
+∞
257.6
181
*
TCC10
NOMESCO Finland
Probing of lacrimal canaliculus/duct
949.4
103.6
92
*
H04.5
ICD-10 Finland
Stenosis and insufficiency of lacrimal passages
61.4
30.6
35
7
CCA20
NOMESCO Finland
Incision of lacrimal punctum or canaliculus
344.0
29.7
29
*
ZXD10
NOMESCO Finland
Scheduled procedure
3.0
11.5
77
358
TCC30
NOMESCO Finland
Intubation of lacrimal canaliculus/duct
116.4
10.5
11
*
XCC00
NOMESCO Finland
Investigative irrigation of lacrimal passages
105.2
9.5
10
*
ZXA10
NOMESCO Finland
Bilateral
2.9
7.6
43
178
ZXE00
NOMESCO Finland
One hour or less
2.4
7.4
79
444
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
60
431
1.59
2.14
4.8
4.3
—
—
—
0
0
52
369
1.57
1.93
3.9
4.3
0.09
0.27
e6/l
1.40
44
272
0
52
0.00
1.91
0.0
1.6
—
0.02
—
0
12
157
1421
1.79
1.90
10.5
10.5
22.10
21.80
mg/l
0.03
113
1011
31
195
1.71
1.84
2.3
2.3
4136.03
3644.73
u/l
—
9
63
6
21
2.92
1.51
1.7
1.1
—
—
—
0
0
32
230
1.47
1.11
4.0
4.0
1.10
1.16
e6/l
0.05
22
131
7
34
2.10
1.04
1.4
1.6
—
—
—
0
0
32
237
1.42
0.96
3.0
2.6
27.67
13.69
ng/l
0.32
15
98
20
134
1.55
0.96
1.4
1.4
150.41
399.74
u/ml
0.69
15
127
7
37
1.93
0.95
15.6
5.4
62.17
52.91
%
—
7
37
12
70
1.76
0.95
2.7
3.3
1.21
1.24
mmol/l
1.26
12
59
28
203
1.45
0.94
1.4
1.4
—
—
—
0
0
43
337
1.36
0.94
4.9
6.2
1.05
1.13
inr
1.10
21
122
46
366
1.34
0.91
2.7
2.1
—
—
—
0
0
10
167
0.57
0.90
7.6
4.2
281.50
290.01
umol/l
—
10
153
48
386
1.33
0.89
6.6
7.6
38.33
37.10
g/l
0.82
48
364
8
44
1.85
0.87
1.4
1.1
—
—
—
0
0
39
309
1.33
0.80
2.6
2.0
—
—
—
0
0
11
67
1.68
0.77
1.1
1.3
—
—
—
0
0
58
489
1.27
0.75
6.2
7.0
20.18
22.99
umol/l
0.17
52
451
5
25
2.03
0.73
1.0
2.2
—
—
—
0
0
7
41
1.73
0.70
6.3
18.6
0.73
0.68
%
—
7
41
7
41
1.73
0.70
6.3
18.6
1.20
1.19
%
—
7
41
5
27
1.87
0.69
1.2
1.5
—
—
—
0
0
28
216
1.35
0.68
7.2
9.0
4.57
5.11
kpa
1.33
28
211
5
29
1.74
0.64
4.8
4.2
87.60
97.34
%
—
5
29
169
1635
1.50
0.63
16.2
14.6
261.95
267.01
e9/l
0.48
164
1573
29
229
1.32
0.61
10.1
10.6
1.35
1.33
mmol/l
0.21
29
220
30
239
1.31
0.60
14.2
14.3
24.99
24.59
mmol/l
0.42
30
239
0
22
0.00
0.59
0.0
1.5
—
—
—
0
0
169
1637
1.48
0.59
16.2
14.5
4.64
4.60
e12/l
0.48
162
1576
13
89
1.50
0.59
8.3
3.6
—
—
—
0
0
30
240
1.30
0.58
2.7
4.5
1.05
1.48
mg/l
0.37
17
162
29
231
1.30
0.58
4.1
4.1
5.55
3.53
e6/l
0.28
19
134
6
36
1.69
0.57
1.0
1.3
—
—
—
0
0
6
38
1.60
0.55
6.3
19.6
21.17
23.55
mmol/l
—
6
38
28
226
1.28
0.52
8.0
9.2
0.95
0.94
mmol/l
0.01
23
172
12
166
0.70
0.50
1.8
1.4
—
—
—
0
0
28
227
1.28
0.50
7.9
9.1
5.89
5.75
kpa
0.45
28
222
95
877
1.17
0.47
8.2
9.1
3.74
3.72
e9/l
0.03
84
732
5
85
0.58
0.46
1.4
1.3
—
—
—
0
0
10
69
1.47
0.45
2.2
1.9
—
—
—
0
0
50
563
0.84
0.43
2.9
2.5
—
—
—
0
0
69
625
1.17
0.42
6.3
4.6
0.00
0.00
estimate
-0.00
13
142
24
196
1.26
0.41
14.0
10.1
9.36
9.43
kpa
0.07
24
188
69
626
1.16
0.41
4.6
3.3
0.00
0.00
estimate
-0.00
13
136
153
1477
1.23
0.41
3.8
4.0
—
—
—
0
0
0
17
0.00
0.41
0.0
1.2
—
—
—
0
0
0
17
0.00
0.41
0.0
4.5
—
—
—
0
0
0
17
0.00
0.41
0.0
4.5
—
—
—
0
0
0
17
0.00
0.41
0.0
1.1
—
81.00
—
0
17
22
179
1.26
0.39
1.4
1.3
—
—
—
0
0
5
36
1.40
0.38
5.6
3.7
125.40
298.47
ug/l
—
5
30
58
522
1.16
0.38
2.9
3.2
—
—
—
0
0
69
630
1.15
0.38
4.6
3.3
0.00
0.00
estimate
-0.00
11
139
9
70
1.30
0.37
6.1
7.7
160.11
172.01
%
—
9
70
79
730
1.14
0.36
3.8
3.1
66.83
47.28
ug/l
0.58
73
679
37
324
1.18
0.34
1.8
1.5
89.84
93.69
pmol/l
0.24
23
163
22
184
1.22
0.32
1.0
1.1
—
—
—
0
0
54
591
0.88
0.31
3.0
2.7
—
—
—
0
0
15
120
1.27
0.31
2.0
2.0
—
—
—
0
0
7
56
1.26
0.30
6.1
4.3
23.57
25.44
nmol/l
—
7
56
11
85
1.31
0.28
5.0
14.6
96.18
86.99
%
0.88
11
85
9
119
0.74
0.28
1.7
2.7
24.89
29.80
u/l
—
9
99
15
122
1.25
0.28
2.1
2.0
—
—
—
0
0
24
207
1.18
0.26
5.4
9.0
23.04
23.15
mmol/l
0.07
24
207
113
1083
1.11
0.26
3.3
3.2
14.55
14.51
pmol/l
0.07
102
956
99
944
1.11
0.24
2.7
2.6
5.23
5.42
mmol/l
1.42
85
859
5
37
1.36
0.23
1.0
1.4
—
—
—
0
0
5
37
1.36
0.23
1.0
1.4
—
—
—
0
0
25
219
1.16
0.23
13.8
9.9
1.74
1.00
mmol/l
0.56
19
155
14
116
1.22
0.22
8.9
9.8
104.00
105.72
mmol/l
0.57
14
116
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
2.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
25
221
1.15
0.21
13.8
9.8
5.24
5.09
kpa
0.49
25
214
0
12
0.00
0.21
0.0
1.6
—
—
—
0
0
93
889
1.09
0.21
2.9
2.8
2.59
2.60
mmol/l
0.02
87
837
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
6
49
1.23
0.20
13.5
13.1
0.88
0.73
%
—
6
49
15
173
0.85
0.17
1.5
4.2
211.40
487.14
ng/l
—
5
94
30
273
1.12
0.17
2.9
3.2
—
—
—
0
0
5
66
0.75
0.17
1.4
1.3
—
—
—
0
0
5
66
0.75
0.17
1.4
1.3
—
—
—
0
0
5
66
0.75
0.17
1.4
1.3
—
—
—
0
0
6
77
0.77
0.16
3.3
1.7
—
—
—
0
0
6
78
0.76
0.16
2.5
2.5
4.32
5.21
pmol/l
—
6
69
6
78
0.76
0.16
1.3
1.4
—
—
—
0
0
6
79
0.75
0.16
1.3
1.4
—
—
—
0
0
9
80
1.13
0.15
2.0
1.8
—
—
—
0
0
9
106
0.84
0.13
1.3
2.2
—
—
—
0
0
49
465
1.07
0.12
4.7
3.1
—
—
—
0
0
91
883
1.06
0.12
2.8
2.7
1.41
1.42
mmol/l
0.07
85
834
16
177
0.89
0.11
14.4
10.0
0.80
0.80
mmol/l
0.21
16
167
20
218
0.91
0.11
1.2
1.4
1.25
1.36
%
0.75
20
198
5
44
1.14
0.10
1.0
1.2
—
—
—
0
0
5
44
1.14
0.10
1.2
1.5
—
—
—
0
0
5
46
1.09
0.09
1.0
1.2
—
—
—
0
0
98
958
1.05
0.09
6.8
7.1
107.80
108.88
ml/min/173m2
0.17
74
682
5
60
0.83
0.08
1.2
1.1
—
16.07
—
0
6
8
78
1.03
0.07
2.1
2.4
—
—
—
0
0
7
82
0.85
0.07
1.1
1.2
—
—
—
0
0
9
84
1.07
0.07
2.6
1.6
—
—
—
0
0
9
87
1.04
0.07
2.1
1.8
—
—
—
0
0
92
904
1.03
0.05
3.0
2.8
4.27
4.34
mmol/l
0.29
86
861
124
1227
1.03
0.04
3.8
3.8
1.99
1.95
mu/l
0.12
115
1143
72
707
1.03
0.04
1.8
1.9
—
—
—
0
0
15
159
0.94
0.03
1.8
2.6
320.13
375.74
nmol/l
0.58
15
151
92
908
1.03
0.03
3.8
3.9
6.80
8.30
mm/h
1.23
82
841
15
151
0.99
0.00
3.0
1.9
—
—
—
0
0
61
606
1.01
0.00
1.7
1.6
1.76
2.75
u/ml
0.27
12
114
18
176
1.02
0.00
2.1
2.0
—
—
—
0
0
34
341
1.00
0.00
5.1
3.5
0.00
0.00
estimate
-0.00
13
136
10
96
1.04
0.00
1.3
1.2
—
—
—
0
0
84
835
1.01
0.00
2.8
2.6
1.00
1.11
mmol/l
1.35
78
797
0
6
0.00
0.00
0.0
6.0
—
—
—
0
0
7
75
0.93
0.00
1.9
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
20.83
—
0
6
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
4.5
—
208.00
—
0
6
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
55.17
—
0
6
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
65
0.92
-0.00
1.0
1.0
2.68
3.29
kpa
—
6
56
6
66
0.91
-0.00
1.0
1.0
7.37
7.51
kpa
—
6
57
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
13.88
—
0
5
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.4
—
—
—
0
0
6
66
0.91
-0.00
1.0
1.0
19.83
18.94
mmol/l
—
6
66
6
66
0.91
-0.00
1.3
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
1.76
—
0
5
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
12.20
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
6
64
0.93
-0.00
1.3
1.3
1.12
1.18
g/l
—
6
59
0
9
0.00
-0.00
0.0
1.0
—
360.78
—
0
9
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: Q17_CONGENITAL_NASOLACRIMAL_DUCT_OBSTRUCTION_OR_STENOSIS – Congenital nasolacrimal duct obstruction or stenosis
GWS hits: -
This endpoint is excluded (different definition than used in FinnGen).