No definition available.
Congenital malformations of eyelid, lacrimal apparatus and orbit
Q17_CONGEN_MALFO_EYELID_LACRIMAL_APPARA_ORBIT
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
339 |
4. Check minimum number of eventsNone |
339 |
5. Include endpointsNone |
339 |
6. Filter based on genotype QC (FinnGen only) |
323 |
Control definitions (FinnGen only)
- Control exclude
- Q17_CONGEN_MALFO_EYE_EAR_FACE_NECK
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- Q1
- Name in latin
- Malformationes congenitae palpebrarum, apparatus lacrimalis et orbitae
Similar endpoints
↥List of similar endpoints to
Congenital malformations of eyelid, lacrimal apparatus and orbit
based on the number of shared cases.
Similar with more cases:
- Congenital malformations of eyelid, lacrimal apparatus and orbit
- Congenital malformations of eye, ear, face and neck
- Congenital malformations, deformations and chromosomal abnormalities
- Congenital malformations, deformations and chromosomal abnormalities
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 12033 | 5863 | 6168 |
| Only index persons | 7548 | 3712 | 3836 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.17 | 0.17 | 0.17 |
| Only index persons | 0.14 | 0.14 | 0.15 |
| Median age at first event (years) | |||
| Whole population | 1.30 | 1.32 | 1.26 |
| Only index persons | 1.36 | 1.40 | 1.32 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 323 | 194 | 129 |
| Unadjusted period prevalence (%) | 0.06 | 0.07 | 0.06 |
| Median age at first event (years) | 3.13 | 2.13 | 4.62 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 339
- Matched controls
- 3389
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q10.5
ICD-10 Finland
Congenital stenosis and stricture of lacrimal duct
986.8
205.0
181
*
Q10.0
ICD-10 Finland
Congenital ptosis
+∞
140.7
125
*
TCC10
NOMESCO Finland
Probing of lacrimal canaliculus/duct
426.4
97.3
93
*
H02.4
ICD-10 Finland
Ptosis of eyelid
48.7
95.9
57
14
H04.5
ICD-10 Finland
Stenosis and insufficiency of lacrimal passages
26.5
56.4
40
17
CBJ40
NOMESCO Finland
Resection of levator muscle of eyelid
137.9
35.4
37
*
CCA20
NOMESCO Finland
Incision of lacrimal punctum or canaliculus
317.7
29.2
29
*
CBJ10
NOMESCO Finland
Fascia plate sling or synthetic material for ptosis correction
+∞
24.3
23
*
ZXD10
NOMESCO Finland
Scheduled procedure
2.8
18.2
143
705
Q10.30
ICD-10 Finland
Other congenital malformations of eyelid
+∞
17.9
17
*
74482
ICD-8 Finland
Congenital anomalies of eye, Ptosis
+∞
17.9
17
*
ZXA10
NOMESCO Finland
Bilateral
2.9
14.2
80
325
CBJ30
NOMESCO Finland
Plastic repair of levator aponeurosis of eyelid
72.6
12.7
14
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.4
11.0
99
502
ZXE00
NOMESCO Finland
One hour or less
2.2
10.6
142
845
TCC30
NOMESCO Finland
Intubation of lacrimal canaliculus/duct
113.4
10.5
11
*
Q10.2
ICD-10 Finland
Congenital entropion
+∞
10.5
10
*
XCK10
NOMESCO Finland
Photography of fundus of eye
3.8
10.3
33
94
XCC00
NOMESCO Finland
Investigative irrigation of lacrimal passages
31.0
9.5
12
*
S01AA01
ATC
chloramphenicol; ophthalmic
4.7
9.4
22
49
ZXA00
NOMESCO Finland
Right side
2.5
9.4
65
290
H02.3
ICD-10 Finland
Blepharochalasis
7.5
8.9
20
28
WX400
NOMESCO Finland
Inhalation anesthesy
3.5
8.4
30
92
ZXA05
NOMESCO Finland
Left side
2.5
8.4
60
271
CBJ99
NOMESCO Finland
Other operation for ptosis
+∞
8.4
8
*
7436B
ICD-9 Finland
Congenital anomalies of eyelids, lachrymal system and orbit[PTOSIS CONGENITA]
+∞
8.4
8
*
3242
FHL
Levator resection
+∞
8.4
8
*
ZXD20
NOMESCO Finland
Day surgery
2.8
8.2
45
178
H53.0
ICD-10 Finland
Amblyopia ex anopsia
6.6
7.8
19
30
S01AX11
ATC
[U] ofloxacin
4.7
7.3
17
38
CJB10
NOMESCO Finland
Laser discission of secondary cataract
4.2
6.4
17
42
Q10.1
ICD-10 Finland
Congenital ectropion
+∞
6.3
6
*
3743A
ICD-9 Finland
Other disorders of eyelids, Ptosis of eyelid[PTOSIS]
+∞
6.3
6
*
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
3.2
6.2
24
78
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
31
152
2.14
3.59
1.7
2.1
11.90
12.84
iu/l
0.10
26
120
297
2691
1.83
3.40
11.9
11.3
24.73
21.57
mg/l
0.68
221
1956
8
15
5.43
3.21
1.6
1.7
135.63
124.73
%
—
8
15
5
6
8.43
2.75
1.0
1.7
—
—
—
0
0
41
246
1.76
2.68
1.5
1.6
996.88
1136.37
nmol/l
0.53
32
181
29
156
1.94
2.66
1.9
2.2
6.61
6.93
u/l
0.08
23
122
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
7
18
3.95
2.26
1.9
1.7
120.29
108.94
%
—
7
18
37
230
1.68
2.16
1.4
1.4
262.09
360.70
u/ml
0.22
31
215
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
5
10
5.05
2.07
3.6
1.3
62.00
126.80
%
—
5
10
0
57
0.00
2.07
0.0
1.4
—
—
—
0
0
21
115
1.88
1.87
2.4
1.3
—
—
—
0
0
224
2003
1.35
1.83
3.4
3.5
14.71
14.54
pmol/l
0.44
204
1808
88
686
1.38
1.79
1.9
1.6
97.24
96.56
pmol/l
0.04
49
355
105
844
1.35
1.76
3.8
4.0
—
—
—
0
0
42
290
1.51
1.63
2.7
2.8
18.51
23.89
%
1.92
35
263
267
2473
1.37
1.60
13.4
12.6
3.94
3.92
mmol/l
0.46
261
2395
43
300
1.50
1.59
2.2
2.3
2904.10
3186.56
u/l
0.03
13
93
81
635
1.36
1.58
2.5
2.6
49.24
58.33
u/l
1.73
75
576
89
712
1.34
1.53
3.4
3.8
0.45
0.33
e6/l
0.14
72
534
9
37
2.47
1.49
3.8
3.7
82.67
98.46
%
—
9
37
9
38
2.40
1.46
1.4
1.4
—
—
—
0
0
92
748
1.32
1.41
7.5
8.6
1.11
1.14
inr
0.21
39
251
126
1069
1.28
1.40
5.5
7.0
17.51
18.31
umol/l
0.08
116
996
122
1031
1.29
1.40
9.0
10.9
1.22
1.23
mmol/l
0.95
112
964
265
2471
1.33
1.37
13.6
12.6
139.54
139.47
mmol/l
0.24
259
2399
282
2655
1.37
1.35
8.0
8.5
24.63
25.36
u/l
0.34
277
2565
72
575
1.32
1.25
2.7
2.9
23.50
29.65
ng/l
0.23
36
291
7
141
0.49
1.24
1.6
1.3
—
—
—
0
0
116
997
1.25
1.12
2.9
2.8
74.23
69.96
nmol/l
0.80
107
918
27
189
1.47
1.02
6.2
5.4
—
—
—
0
0
77
915
0.79
0.99
3.1
2.6
—
—
—
0
0
59
474
1.30
0.99
2.7
3.6
1.22
1.26
mg/l
0.04
34
339
5
23
2.19
0.98
1.2
2.8
—
—
—
0
0
247
2319
1.24
0.98
4.2
4.1
1.95
1.92
mu/l
0.12
231
2159
264
2497
1.26
0.97
15.9
14.6
13.67
13.72
%
0.08
259
2455
7
36
1.96
0.97
1.4
1.9
—
—
—
0
0
7
37
1.91
0.94
1.6
1.4
—
—
—
0
0
318
3089
1.47
0.93
18.2
16.1
264.23
262.12
e9/l
0.24
308
2991
151
1357
1.20
0.92
5.8
6.6
6.14
6.15
mmol/l
0.01
143
1238
6
28
2.16
0.92
1.3
1.3
—
—
—
0
0
318
3092
1.45
0.88
18.4
16.6
40.13
41.73
%
0.53
305
2957
25
180
1.42
0.84
5.7
7.4
70.93
61.98
ng/l
0.21
20
169
318
3095
1.44
0.84
18.2
16.0
4.61
4.59
e12/l
0.28
305
2993
147
1327
1.19
0.83
3.6
3.1
78.38
64.17
ug/l
0.57
137
1240
73
856
0.81
0.83
2.9
2.5
—
—
—
0
0
8
47
1.72
0.81
2.1
1.9
—
—
—
0
0
8
47
1.72
0.81
2.1
1.9
—
—
—
0
0
15
98
1.55
0.79
10.3
16.3
0.71
0.71
%
0.02
15
98
0
25
0.00
0.79
0.0
1.9
—
—
—
0
0
318
3099
1.42
0.79
18.5
16.2
134.76
135.26
g/l
0.25
313
3055
33
253
1.34
0.78
2.2
1.8
—
—
—
0
0
124
1109
1.19
0.77
9.0
10.4
1.22
1.23
mmol/l
1.06
111
984
6
34
1.78
0.76
1.7
1.1
—
—
—
0
0
0
28
0.00
0.76
0.0
4.1
—
—
—
0
0
0
28
0.00
0.76
0.0
4.1
—
—
—
0
0
70
594
1.22
0.76
4.4
3.0
1.01
1.02
kg/l
0.42
14
90
177
1633
1.17
0.76
9.4
10.1
3.87
3.84
e9/l
0.06
157
1389
44
354
1.28
0.75
11.2
9.9
1.34
1.03
mmol/l
0.28
32
250
46
374
1.27
0.73
11.7
14.8
24.85
24.49
mmol/l
0.46
46
374
52
430
1.25
0.71
3.2
3.5
1.21
1.02
e6/l
0.24
33
242
44
358
1.26
0.69
11.2
9.8
5.18
5.07
kpa
0.42
44
346
18
127
1.44
0.69
1.6
3.2
89.25
77.40
ml/min/173m2
—
8
52
76
657
1.20
0.69
3.2
2.3
2.72
2.67
mg/l
0.09
69
566
39
314
1.27
0.67
1.6
1.6
520.71
24101180.03
pmol/l
0.50
34
278
7
43
1.64
0.67
1.4
1.6
—
—
—
0
0
19
137
1.41
0.66
1.8
1.8
—
—
—
0
0
15
103
1.48
0.66
3.4
3.7
0.06
0.09
e6/l
0.25
15
97
37
298
1.27
0.64
11.8
10.4
9.11
9.45
kpa
0.56
37
287
40
326
1.26
0.63
3.6
4.8
6.06
8.27
umol/l
0.55
33
268
117
1060
1.16
0.61
2.9
3.0
—
—
—
0
0
50
420
1.22
0.61
1.4
1.4
—
—
—
0
0
8
51
1.58
0.61
1.4
1.7
—
—
—
0
0
12
174
0.68
0.61
2.1
2.2
—
11.60
—
0
11
0
21
0.00
0.60
0.0
1.2
—
184.40
—
0
21
0
22
0.00
0.59
0.0
1.0
—
—
—
0
0
0
23
0.00
0.58
0.0
1.0
—
—
—
0
0
21
159
1.34
0.57
8.2
14.6
14.68
13.83
kpa
0.22
21
154
21
159
1.34
0.57
8.2
14.6
5.38
5.19
kpa
0.28
21
153
9
60
1.51
0.54
2.0
1.5
—
—
—
0
0
9
61
1.49
0.54
2.0
1.8
—
—
—
0
0
9
61
1.49
0.54
2.0
1.8
—
—
—
0
0
9
132
0.67
0.53
2.7
1.7
—
—
—
0
0
43
362
1.21
0.52
3.9
4.9
594.36
1010.72
ng/l
0.59
37
303
9
64
1.42
0.52
4.6
3.3
128.00
281.35
ug/l
—
9
56
31
252
1.25
0.52
2.2
1.7
—
—
—
0
0
19
144
1.34
0.51
4.2
10.9
96.37
87.72
%
1.45
19
144
9
65
1.39
0.51
1.3
1.6
—
—
—
0
0
209
1989
1.13
0.50
3.6
3.1
5.50
5.58
mmol/l
0.44
188
1829
21
163
1.31
0.49
1.2
1.2
0.08
3.24
u/ml
2.89
14
107
7
47
1.50
0.48
1.7
1.9
—
—
—
0
0
10
68
1.48
0.47
1.6
1.7
—
—
—
0
0
7
49
1.44
0.46
1.0
1.8
—
—
—
0
0
5
84
0.59
0.46
3.6
2.1
42.00
36.45
u/l
—
5
74
11
78
1.42
0.43
10.6
5.8
55.59
52.30
%
0.18
11
78
8
56
1.44
0.43
1.4
1.5
—
—
—
0
0
5
32
1.57
0.42
1.2
1.4
—
—
—
0
0
5
32
1.57
0.42
1.0
1.1
—
—
—
0
0
5
33
1.52
0.41
1.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.2
—
—
—
0
0
14
182
0.76
0.40
1.4
1.3
—
—
—
0
0
11
80
1.39
0.39
1.1
1.2
—
—
—
0
0
9
67
1.35
0.38
1.0
1.4
—
—
—
0
0
47
413
1.16
0.38
1.6
1.4
16.33
20.51
nmol/l
1.49
41
352
32
272
1.19
0.37
1.4
1.3
—
—
—
0
0
17
135
1.27
0.36
2.1
1.7
—
—
—
0
0
9
121
0.74
0.36
1.3
1.4
—
—
—
0
0
9
121
0.74
0.36
1.3
1.4
—
—
—
0
0
9
121
0.74
0.36
1.3
1.4
—
—
—
0
0
9
121
0.74
0.36
1.3
1.4
—
—
—
0
0
6
42
1.44
0.35
1.0
1.0
—
—
—
0
0
6
42
1.44
0.35
1.3
1.5
22.80
14.50
u/l
—
6
37
10
73
1.38
0.35
1.0
1.3
—
—
—
0
0
10
73
1.38
0.35
1.0
1.3
—
—
—
0
0
6
44
1.37
0.34
1.7
4.0
—
—
—
0
0
28
238
1.19
0.33
11.1
10.8
104.39
105.10
mmol/l
0.31
28
238
47
418
1.14
0.33
3.4
3.8
4.59
3.16
e6/l
0.29
28
233
42
371
1.15
0.32
1.2
1.2
14.57
26.44
iu/ml
1.16
12
99
40
353
1.15
0.31
2.1
1.8
—
—
—
0
0
10
131
0.76
0.31
2.5
1.7
—
—
—
0
0
15
120
1.26
0.30
2.1
1.8
—
—
—
0
0
207
2001
1.09
0.29
9.4
8.9
101.94
100.20
ml/min/173m2
0.47
160
1494
252
2579
0.91
0.29
3.8
3.9
—
—
—
0
0
16
194
0.82
0.28
3.8
3.8
24.61
21.72
%
—
10
77
150
1433
1.08
0.28
6.9
7.3
53.88
52.46
%
0.62
145
1364
42
377
1.13
0.27
6.0
9.3
0.85
1.04
mmol/l
0.18
32
283
21
178
1.19
0.27
3.2
2.8
—
—
—
0
0
61
561
1.11
0.26
2.4
2.2
—
—
—
0
0
10
77
1.31
0.26
1.9
1.8
—
—
—
0
0
204
1977
1.08
0.26
3.7
3.4
2.76
2.66
mmol/l
0.86
190
1856
9
74
1.22
0.25
1.3
1.5
—
—
—
0
0
11
87
1.27
0.24
1.1
1.1
0.07
0.50
u/ml
—
5
37
5
38
1.32
0.23
1.0
1.4
—
—
—
0
0
52
478
1.10
0.23
2.3
2.0
—
—
—
0
0
10
79
1.27
0.22
2.0
2.0
—
—
—
0
0
0
10
0.00
0.21
0.0
2.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.7
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
44.89
—
0
10
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
3.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
10.18
—
0
11
0
10
0.00
0.21
0.0
6.6
—
—
—
0
0
25
281
0.88
0.20
1.6
1.4
—
—
—
0
0
126
1210
1.07
0.20
4.2
3.3
0.00
0.00
estimate
-0.00
24
263
17
146
1.17
0.19
1.2
1.2
7.89
1.91
u/ml
0.38
12
101
6
52
1.16
0.19
1.0
1.3
—
10.94
—
0
9
126
1212
1.06
0.19
5.9
4.6
0.00
0.00
estimate
-0.00
24
266
109
1136
0.94
0.18
1.9
1.9
—
—
—
0
0
36
392
0.91
0.18
4.4
4.2
7.46
56.06
mg/mmol
0.59
26
261
71
671
1.07
0.18
4.2
3.0
2.38
2.38
mmol/l
0.03
66
610
7
60
1.17
0.18
1.3
1.2
—
—
—
0
0
16
138
1.17
0.17
2.1
1.7
—
—
—
0
0
7
61
1.15
0.17
1.7
1.5
—
—
—
0
0
32
350
0.91
0.17
9.9
8.8
0.80
0.81
mmol/l
0.53
32
330
19
167
1.15
0.17
13.3
17.8
1.08
1.14
mg/l
0.40
19
162
8
71
1.13
0.16
2.0
1.9
0.31
0.58
nmol/l
—
8
60
192
1877
1.05
0.15
3.2
3.0
1.18
1.19
mmol/l
0.06
178
1767
6
80
0.75
0.15
1.7
1.9
—
—
—
0
0
10
83
1.21
0.15
1.1
1.2
—
—
—
0
0
12
140
0.85
0.15
1.3
1.4
—
—
—
0
0
12
102
1.18
0.15
1.2
1.1
—
9.94
—
0
13
16
140
1.15
0.15
1.4
1.4
—
—
—
0
0
126
1220
1.05
0.15
4.2
3.3
0.00
0.00
estimate
-0.00
20
258
7
86
0.81
0.14
1.4
1.2
—
—
—
0
0
7
88
0.79
0.14
1.1
1.6
—
0.02
—
0
20
7
88
0.79
0.14
1.6
2.0
—
—
—
0
0
60
569
1.07
0.14
2.9
2.9
—
—
—
0
0
12
138
0.86
0.13
2.3
2.6
0.67
0.63
ug/l
—
7
86
10
117
0.85
0.13
1.2
1.3
—
—
—
0
0
10
85
1.18
0.12
1.4
1.2
—
—
—
0
0
22
240
0.91
0.11
4.7
5.4
301.55
264.46
u/l
0.19
22
233
16
178
0.89
0.11
1.3
1.4
218.62
267.71
miu/ml
—
10
92
94
910
1.05
0.11
4.3
3.1
—
—
—
0
0
202
1988
1.04
0.11
3.5
3.2
4.49
4.44
mmol/l
0.27
188
1884
14
125
1.12
0.10
1.5
1.4
—
—
—
0
0
12
135
0.88
0.10
1.3
1.6
—
—
—
0
0
199
1961
1.04
0.09
3.4
3.2
1.38
1.42
mmol/l
0.66
187
1843
6
54
1.11
0.09
3.0
3.3
19.38
74.07
u/ml
—
6
54
7
67
1.05
0.08
1.9
2.4
140.86
131.46
g/l
—
7
48
8
74
1.08
0.07
1.5
3.2
3.67
3.36
mmol/l
—
8
69
8
75
1.07
0.07
1.0
1.1
—
—
—
0
0
181
1788
1.03
0.06
4.0
3.8
8.22
8.80
mm/h
0.36
165
1654
30
286
1.05
0.06
1.0
1.0
—
—
—
0
0
96
977
0.98
0.05
1.6
1.5
1.27
2.67
u/ml
0.76
20
199
13
120
1.09
0.05
1.0
1.0
6.99
8.35
mu/l
0.48
13
113
67
658
1.02
0.03
4.7
3.4
0.00
0.00
estimate
-0.00
23
252
24
231
1.04
0.03
1.6
1.3
—
—
—
0
0
14
148
0.94
0.02
1.3
1.2
—
—
—
0
0
170
1709
0.99
0.01
4.5
4.1
36.96
37.26
mmol/mol
0.17
157
1607
10
99
1.01
0.00
1.3
1.3
0.22
0.22
g/l
—
10
94
10
103
0.97
0.00
8.7
12.0
0.85
0.67
%
—
10
103
26
258
1.01
0.00
5.2
4.3
1.77
1.74
ug/l
0.02
20
227
35
352
0.99
0.00
3.2
3.8
406.36
499.60
ng/l
0.11
14
204
23
232
0.99
0.00
2.6
2.1
—
—
—
0
0
24
238
1.01
0.00
1.4
1.3
54.80
141.08
iu/ml
—
5
80
18
180
1.00
0.00
2.2
2.1
—
—
—
0
0
35
355
0.98
0.00
1.3
1.2
14.32
4.99
u/ml
0.31
13
130
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
2.6
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
30.01
—
0
9
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
6.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
8.87
—
0
5
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
73
0.96
-0.00
6.4
9.9
—
2985.67
—
0
9
Mortality – FinRegistry
↥Association
Association between endpoint Q17_CONGEN_MALFO_EYELID_LACRIMAL_APPARA_ORBIT and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| Q17_CONGEN_MALFO_EYELID_LACRIMAL_APPARA_ORBIT | 1.242 [0.85, 1.81] | 0.263 |
| Birth year | 1.0 [0.99, 1.01] | 0.939 |
During the follow-up period (1.1.1998 — 31.12.2019), 61 out of 5131 females with Q17_CONGEN_MALFO_EYELID_LACRIMAL_APPARA_ORBIT died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| Q17_CONGEN_MALFO_EYELID_LACRIMAL_APPARA_ORBIT | 1.42 [1.06, 1.9] | 0.018 |
| Birth year | 0.986 [0.98, 1.0] | 0.004 |
During the follow-up period (1.1.1998 — 31.12.2019), 66 out of 5456 males with Q17_CONGEN_MALFO_EYELID_LACRIMAL_APPARA_ORBIT died.
Mortality risk
Mortality risk for people of age
years, who have Q17_CONGEN_MALFO_EYELID_LACRIMAL_APPARA_ORBIT.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.099% | 0.215% |
| 5 | 0.743% | 1.521% |
| 10 | 2.266% | 4.077% |
| 15 | 4.051% | 7.793% |
| 20 | 7.108% | 12.713% |
Relationships between endpoints
↥Index endpoint: Q17_CONGEN_MALFO_EYELID_LACRIMAL_APPARA_ORBIT – Congenital malformations of eyelid, lacrimal apparatus and orbit
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data