Congenital malformations of eye, ear, face and neck

Q17_CONGEN_MALFO_EYE_EAR_FACE_NECK

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 Q10-Q18
  • Cause of death: ICD-10 Q10-Q18

2 out of 7 registries used, show all original rules.

2805

4. Check minimum number of events

None

2805

5. Include endpoints

2805

6. Filter based on genotype QC (FinnGen only)

2678

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
Q
Name in latin
Malformationes congenitae oculorum, aurium, faciei et colli

Similar endpoints

List of similar endpoints to Congenital malformations of eye, ear, face and neck based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 42386 21671 20654
Only index persons 33417 17407 16010
Unadjusted period prevalence (%)
Whole population 0.60 0.62 0.58
Only index persons 0.63 0.64 0.61
Median age at first event (years)
Whole population 6.75 7.53 5.86
Only index persons 11.62 13.48 9.60

-FinnGen-

Key figures

All Female Male
Number of individuals 2678 1688 990
Unadjusted period prevalence (%) 0.55 0.60 0.45
Median age at first event (years) 32.53 28.86 38.80

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2805
Matched controls
28046
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q17.5
ICD-10 Finland
Prominent ear
4507.0
307.7
400
*
ENB40
NOMESCO Finland
Excision of branchial cyst or fistula
1602.8
307.7
411
*
Q18.8
ICD-10 Finland
Other specified congenital malformations of face and neck
+∞
307.7
333
*
Q18.0
ICD-10 Finland
Sinus, fistula and cyst of branchial cleft
+∞
307.7
697
*
DAD30
NOMESCO Finland
Plastic repair of auricle
+∞
307.7
367
*
Q13.2
ICD-10 Finland
Other congenital malformations of iris
2592.9
260.3
248
*
Q18.1
ICD-10 Finland
Preauricular sinus and cyst
+∞
197.2
187
*
R22.1
ICD-10 Finland
Localized swelling, mass and lump, neck
6.9
185.3
306
491
Q10.5
ICD-10 Finland
Congenital stenosis and stricture of lacrimal duct
324.7
180.3
181
6
Q12.0
ICD-10 Finland
Congenital cataract
+∞
175.9
167
*
ENB50
NOMESCO Finland
Excision of cyst or fistula of thyroglossic duct
346.9
164.9
165
5
TCC10
NOMESCO Finland
Probing of lacrimal canaliculus/duct
33.5
151.4
97
30
Q10.0
ICD-10 Finland
Congenital ptosis
433.2
125.9
125
*
EP1AE
NOMESCO Finland
Neck ultrasound examination
4.1
88.2
258
674
Q14.10
ICD-10 Finland
Congenital retinoschis
768.8
76.7
75
*
Q17.2
ICD-10 Finland
Microtia
+∞
71.1
68
*
Q16.1
ICD-10 Finland
Congenital absence, atresia and stricture of auditory canal (external)
705.5
70.4
69
*
DAB20
NOMESCO Finland
Closure of preauricular fistula
+∞
64.8
62
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.0
56.5
777
4444
H27.0
ICD-10 Finland
Aphakia
23.1
56.4
41
18
Q14.2
ICD-10 Finland
Congenital malformation of optic disc
+∞
50.1
48
*
ZXD10
NOMESCO Finland
Scheduled procedure
1.9
49.2
1005
6501
EP1DG
NOMESCO Finland
Very extensive examination of soft tissue of neck with high intesity magnet
10.2
48.7
55
55
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
6.9
46.3
72
107
Q15.0
ICD-10 Finland
Congenital glaucoma
+∞
44.9
43
*
ZXA10
NOMESCO Finland
Bilateral
2.1
44.9
497
2599
ZXE10
NOMESCO Finland
More than one and less than three hours
1.8
44.2
905
5819
L02.1
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of neck
7.9
42.1
58
75
H90.0
ICD-10 Finland
Conductive hearing loss, bilateral
8.7
41.8
53
62
ZXA00
NOMESCO Finland
Right side
1.9
41.5
598
3427
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
8.6
40.0
51
60
CBJ40
NOMESCO Finland
Resection of levator muscle of eyelid
10.9
40.0
43
40
DAD10
NOMESCO Finland
Reconstruction of auricle
392.8
39.2
39
*
Q14.8
ICD-10 Finland
Other congenital malformations of posterior segment of eye
+∞
36.5
35
*
H02.4
ICD-10 Finland
Ptosis of eyelid
4.3
35.2
93
224
H90.1
ICD-10 Finland
Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
5.2
33.5
69
135
Z01.1
ICD-10 Finland
Examination of ears and hearing
2.0
33.4
403
2157
L04.0
ICD-10 Finland
Acute lymphadenitis of face, head and neck
4.9
31.6
70
146
Q16.0
ICD-10 Finland
Congenital absence of (ear) auricle
+∞
31.3
30
*
Z3229
NOMESCO Finland
Other healthcare associate professional
2.3
31.1
245
1108
H33.1
ICD-10 Finland
Retinoschisis and retinal cysts
10.8
30.4
33
31
Q18.9
ICD-10 Finland
Congenital malformation of face and neck, unspecified
+∞
30.3
29
*
Q18.2
ICD-10 Finland
Other branchial cleft malformations
+∞
30.3
29
*
ZXA05
NOMESCO Finland
Left side
1.8
29.7
520
3137
S01ED01
ATC
timolol; ophthalmic
4.0
29.3
84
215
Q17.3
ICD-10 Finland
Other misshapen ear
+∞
29.2
28
*
Q16.3
ICD-10 Finland
Congenital malformation of ear ossicles
+∞
29.2
28
*
H53.0
ICD-10 Finland
Amblyopia ex anopsia
4.5
26.7
65
147
Z96.1
ICD-10 Finland
Presence of intraocular lens
2.2
26.6
225
1048
UDC00
NOMESCO Finland
Ear microscopy
2.2
26.3
237
1132
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
7.9
25.5
35
45
Q13.0
ICD-10 Finland
Coloboma of iris
+∞
25.0
24
*
DAB00
NOMESCO Finland
Excision of lesion of auricle
7.2
25.0
37
52
CBJ10
NOMESCO Finland
Fascia plate sling or synthetic material for ptosis correction
+∞
24.0
23
*
ZXE00
NOMESCO Finland
One hour or less
1.5
23.6
1004
7505
XCK00
NOMESCO Finland
Perimetry
2.6
23.5
136
533
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
2.3
23.4
179
799
Q89.23
ICD-10 Finland
Cyst of the ductus thyreoglossus
36.6
23.0
29
8
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.0
22.8
281
1506
S01EC01
ATC
acetazolamide; systemic
4.1
22.5
61
150
H90.6
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, bilateral
4.6
22.4
53
117
Q14.18
ICD-10 Finland
Congenital malformation of retina
+∞
21.9
21
*
XCK10
NOMESCO Finland
Photography of fundus of eye
2.2
21.8
203
982
XW1AT
NOMESCO Finland
Biopsy from other organ close to skin with ultrasound quidance
6.7
21.7
34
51
S01EC03
ATC
dorzolamide; ophthalmic
6.9
21.6
33
48
CCA20
NOMESCO Finland
Incision of lacrimal punctum or canaliculus
19.0
21.3
32
17
DFF00
NOMESCO Finland
Pure tone audiometry
2.1
21.2
223
1129
H04.5
ICD-10 Finland
Stenosis and insufficiency of lacrimal passages
3.7
20.2
64
176
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.7
19.9
446
2855
Q17.0
ICD-10 Finland
Accessory auricle
+∞
19.8
19
*
Z31.5
ICD-10 Finland
Genetic counselling
2.1
19.7
190
931
CKD60
NOMESCO Finland
Anterior vitrectomy
8.2
19.6
26
32
DBD20
NOMESCO Finland
Plastic repair of external auditory canal
19.5
19.5
29
15
S01EA05
ATC
brimonidine; ophthalmic
4.1
19.4
53
131
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
2.8
19.4
98
358
DAX00
NOMESCO Finland
Adjustment or review of hearing aid
2.8
19.1
96
350
ZXB10
NOMESCO Finland
Medial
5.7
19.0
35
62
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.9
18.9
272
1532
Q17.8
ICD-10 Finland
Other specified congenital malformations of ear
+∞
18.8
18
*
7433A
ICD-9 Finland
Congenital anomalies of eye, Congenital cataract and lens anomalies
70.4
18.7
21
*
H90.7
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
4.9
18.5
40
82
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.1
18.4
186
928
S01ED51
ATC
timolol, combinations; ophthalmic
2.4
18.2
131
569
QA4S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in face
6.3
18.0
30
48
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
4.1
17.8
49
122
Q10.30
ICD-10 Finland
Other congenital malformations of eyelid
+∞
17.7
17
*
WX110
NOMESCO Finland
Infiltration anesthesia
1.5
17.2
1999
17680
WX402
NOMESCO Finland
General anaesthesia
1.5
17.2
542
3756
S01EX03, ,
ATC
5.1
17.1
36
72
114
Kela drug reimbursment
Glaucoma
2.3
17.0
132
593
EP2AT
NOMESCO Finland
Neck soft tissue cytology with ultrasound guidance
17.5
16.9
26
15
74439
ICD-8 Finland
Congenital anomalies of eye, Cataracta NUD
63.7
16.7
19
*
H55
ICD-10 Finland
Nystagmus and other irregular eye movements
6.0
16.5
29
49
DC1AD
NOMESCO Finland
Temporalbone CT
4.7
16.1
37
80
UJC01
NOMESCO Finland
Scopy of lower throat
5.6
16.0
30
54
XCD00
NOMESCO Finland
Clinical examination of eye in general anaesthesia
12.3
15.8
28
23
R5130
NOMESCO Finland
Repair work or maintenance done on the aid
3.0
15.7
69
234
Q87.88
ICD-10 Finland
Other specified congenital malformation syndromes, not elsewhere classified
15.7
15.7
25
16
Q13.1
ICD-10 Finland
Absence of iris
+∞
15.6
15
*
74482
ICD-8 Finland
Congenital anomalies of eye, Ptosis
85.6
15.6
17
*
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.2
15.3
135
639
EP1CM
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with 3 Tesla magnet
20.1
15.1
22
11
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
5.3
14.7
29
55
Q17.9
ICD-10 Finland
Congenital malformation of ear, unspecified
+∞
14.6
14
*
DBD30
NOMESCO Finland
Correction of atresia of external auditory canal
+∞
14.6
14
*
DEE00
NOMESCO Finland
Osseous fixation of hearing aid
80.5
14.6
16
*
J01DA01
ATC
[U] cefalexin
1.4
14.5
1457
12381
P85
ICPC
Mental retardation
5.8
14.5
26
45
JDB10
NOMESCO Finland
Percutaneous gastrostomy
4.2
14.4
38
92
CHF05
NOMESCO Finland
Transscleral laser coagulation of ciliary body
11.4
14.3
26
23
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.5
14.1
599
4392
ZXE20
NOMESCO Finland
More than three and less than five hours
1.7
13.7
280
1743
J01DB01
ATC
cefalexin; oral
1.4
13.6
2173
19803
XCW99
NOMESCO Finland
Other investigative procedure of eye
1.8
13.6
213
1231
Q13.4
ICD-10 Finland
Other congenital corneal malformations
+∞
13.5
13
*
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
13.4
517
3717
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.4
13.4
803
6259
CJB10
NOMESCO Finland
Laser discission of secondary cataract
2.2
13.3
113
528
Q21.00
ICD-10 Finland
Multiple ventricular septal defect
5.8
13.2
24
42
R22.0
ICD-10 Finland
Localized swelling, mass and lump, head
2.6
13.1
77
305
WX400
NOMESCO Finland
Inhalation anesthesy
2.0
13.1
135
679
C77.0
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Lymph nodes of head, face and neck
10.1
13.0
25
25
S01AX11
ATC
[U] ofloxacin
2.6
12.7
72
280
UDH02
NOMESCO Finland
Rhinopharyngoscopy
1.9
12.7
165
900
D11.0
ICD-10 Finland
Benign neoplasm: Parotid gland
3.4
12.6
44
130
Q14.0
ICD-10 Finland
Congenital malformation of vitreous humour
+∞
12.5
12
*
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.8
12.2
201
1178
H26.00
ICD-10 Finland
Infantile, juvenile and presenile cataract
37.7
12.2
15
*
F79.0
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
4.6
11.6
27
59
3793A
ICD-9 Finland
Other disorders of eye, Aphakia and other disorders of lens[APHAKIA]
65.2
11.6
13
*
CHD50
NOMESCO Finland
Shunt operation on anterior chamber
23.0
11.6
16
7
Q12.1
ICD-10 Finland
Congenital displaced lens
+∞
11.5
11
*
Q16.9
ICD-10 Finland
Congenital malformation of ear causing impairment of hearing, unspecified
+∞
11.5
11
*
Q67.0
ICD-10 Finland
Facial asymmetry
35.2
11.3
14
*
TCG10
NOMESCO Finland
Removal of sutures from cornea
8.9
11.2
23
26
ZXD20
NOMESCO Finland
Day surgery
1.6
11.2
284
1862
H50.1
ICD-10 Finland
Divergent concomitant strabismus
4.0
11.2
31
78
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
3.7
11.1
34
92
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
3.0
11.1
48
162
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
1.7
11.0
216
1328
D18.1
ICD-10 Finland
Lymphangioma, any site
11.2
11.0
20
18
H26.2
ICD-10 Finland
Complicated cataract
3.8
11.0
33
88
H26.4
ICD-10 Finland
After-cataract
2.0
11.0
125
653
R2120
NOMESCO Finland
Counselling and guidance concerning rehabilitation services and social security
4.5
10.9
26
58
R59.1
ICD-10 Finland
Generalized enlarged lymph nodes
3.3
10.9
41
127
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.5
10.9
366
2551
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
10.9
670
5214
S01EA03
ATC
apraclonidine; ophthalmic
4.4
10.7
26
59
S01EC04
ATC
brinzolamide; ophthalmic
2.6
10.7
62
245
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.4
10.6
470
3458
S01EE01
ATC
latanoprost; ophthalmic
2.2
10.6
89
415
8260/3-C73.9
ICD-O-3
Papillary adenocarcinoma, NOS, of thyroid gland
3.7
10.5
33
91
Z97.4
ICD-10 Finland
Presence of external hearing-aid
2.4
10.4
69
290
Q10.2
ICD-10 Finland
Congenital entropion
+∞
10.4
10
*
Q16.4
ICD-10 Finland
Other congenital malformations of middle ear
+∞
10.4
10
*
TPH04
NOMESCO Finland
Cathetrisation of vein
1.4
10.4
441
3217
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
4.1
10.4
28
69
KFH00
NOMESCO Finland
Operation for undescended or ectopic testis
8.2
10.3
22
27
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
1.7
10.3
171
1006
C73.91
ICD-10 Finland
Papillary carcinoma of the thyroid gland (thyroid gland)
3.3
10.3
37
112
S01EC54
ATC
brinzolamide, combinations; ophthalmic
4.6
10.2
24
53
3768
FHL
Eye examination under general anesthesia
23.4
10.2
14
6
H44.5
ICD-10 Finland
Degenerated conditions of globe
23.4
10.2
14
6
ZZG00
NOMESCO Finland
Graft of cartilage
11.3
10.0
18
16
RL140, ,
NOMESCO Finland
5.0
10.0
21
42
8070/3-C09.9
ICD-O-3
Squamous cell carcinoma, NOS, of tonsil, NOS
26.1
9.8
13
5
XCD10
NOMESCO Finland
Electrophysiological examination of eye
2.7
9.8
52
197
R13
ICD-10 Finland
Dysphagia
1.8
9.6
132
733
R51.80
ICD-10 Finland
Headache
1.4
9.6
436
3217
Q21.08
ICD-10 Finland
Other specifed ventricular septal defect
3.7
9.6
29
78
WX140
NOMESCO Finland
Parabulbar anesthesy
2.2
9.5
74
335
Q87.03
ICD-10 Finland
Syndrome Goldenhar
100.4
9.4
10
*
H54.1
ICD-10 Finland
Severe visual impairment, binocular
30.1
9.4
12
*
DAW99
NOMESCO Finland
Other operation on auricle
17.6
9.4
14
8
DFF15
NOMESCO Finland
Speech audiometry
2.2
9.4
79
369
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
1.9
9.4
120
652
H50.0
ICD-10 Finland
Convergent concomitant strabismus
3.1
9.4
39
129
7442B
ICD-9 Finland
Congenital anomalies of ear, face and neck, Other specified anomalies of ear[MICROTIA]
+∞
9.4
9
*
74420
ICD-8 Finland
Congenital anomalies of eye, Buphthalmus (glaucoma)
+∞
9.4
9
*
Q11.1
ICD-10 Finland
Other anophthalmos
+∞
9.4
9
*
DAX08
NOMESCO Finland
Fitting of hearing aid
2.2
9.2
78
365
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.8
9.2
125
692
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.1
9.2
84
406
QAA10
NOMESCO Finland
Incision of skin of head or neck
11.5
9.1
16
14
H27.1
ICD-10 Finland
Dislocation of lens
10.1
9.0
17
17
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.3
8.9
862
7132
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
1.8
8.9
136
782
Z3231
NOMESCO Finland
Registered nurse
1.3
8.8
623
4936
ZXC10
NOMESCO Finland
Use of laser
2.5
8.7
51
203
UGC02
NOMESCO Finland
Rigid bronchoscopy
4.6
8.6
20
44
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
1.8
8.6
118
657
CJD20
NOMESCO Finland
Extracapsular cataract extraction with implantation of artificial lens in posterior chamber
11.6
8.6
15
13
WX704
NOMESCO Finland
Intubation
1.7
8.5
167
1028
WX002
NOMESCO Finland
Sedation and analgesia
1.4
8.5
352
2554
ENB99
NOMESCO Finland
Other excision of pharynx and adjacent structures
27.6
8.5
11
*
DDA00
NOMESCO Finland
Stapedotomy
4.2
8.4
22
53
S01CA02
ATC
prednisolone and antiinfectives; ophthalmic
3.9
8.4
24
62
QAB10
NOMESCO Finland
Major dressing of wound of skin of head or neck
4.3
8.4
21
49
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
8.4
901
7550
7432A
ICD-9 Finland
Congenital anomalies of eye, Buphthalmos[GLAUCOMA CONGENITUM]
+∞
8.3
8
*
Q11.2
ICD-10 Finland
Microphthalmos
+∞
8.3
8
*
CBJ30
NOMESCO Finland
Plastic repair of levator aponeurosis of eyelid
8.5
8.3
17
20
R5210
NOMESCO Finland
Assessment of the improvements needed in the living environment
9.5
8.3
16
17
N02BE01
ATC
paracetamol; systemic, rectal
1.3
8.1
2157
20122
CK2L4
NOMESCO Finland
Wide-field/panoramic imaging of ocular fundus
3.6
8.1
26
73
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.3
8.1
669
5410
S01EB01
ATC
pilocarpine; ophthalmic
8.1
8.1
17
21
CJF10
NOMESCO Finland
Secondary implantation of artificial lens in posterior chamber
17.2
8.1
12
7
H26.01
ICD-10 Finland
Infantile, juvenile and presenile cataract
11.7
8.1
14
12
D18.0
ICD-10 Finland
Haemangioma, any site
2.3
8.0
56
243
Q25.0
ICD-10 Finland
Patent ductus arteriosus
3.9
8.0
23
60
WX100
NOMESCO Finland
Conjunctival surface anesthesia
1.7
8.0
149
907
D34
ICD-10 Finland
Benign neoplasm of thyroid gland
4.0
7.9
22
56
Q53.1
ICD-10 Finland
Undescended testicle, unilateral
4.6
7.9
18
39
Z3226
NOMESCO Finland
Physiotherapist
1.4
7.8
389
2914
H57.0
ICD-10 Finland
Anomalies of pupillary function
3.7
7.7
24
66
K11.2
ICD-10 Finland
Sialoadenitis
2.1
7.7
73
358
4105
FHL
Earlobe reconstruction or plastic
45.1
7.7
9
*
Z46.1
ICD-10 Finland
Fitting and adjustment of hearing aid
2.0
7.7
80
407
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
1.7
7.6
130
774
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
7.5
1105
9576
ZXD05
NOMESCO Finland
Urgent procedure
1.3
7.5
679
5548
C09.0
ICD-10 Finland
Malignant neoplasm: Tonsillar fossa
10.0
7.5
14
14
SPAT1153
SPAT
Removal of sutures
1.3
7.5
577
4616
3242
FHL
Levator resection
80.3
7.4
8
*
7436B
ICD-9 Finland
Congenital anomalies of eyelids, lachrymal system and orbit[PTOSIS CONGENITA]
80.3
7.4
8
*
H52.0
ICD-10 Finland
Hypermetropia
2.1
7.4
65
310
J01MA02
ATC
ciprofloxacin; systemic
1.3
7.4
702
5773
D21.0
ICD-10 Finland
Benign neoplasm: Connective and other soft tissue of head, face and neck
6.0
7.4
19
32
ENA32
NOMESCO Finland
Incision of deep pharyngeal infection
8.4
7.3
15
18
H60.9
ICD-10 Finland
Otitis externa, unspecified
1.5
7.3
191
1263
3719
FHL
Other measure in this category
+∞
7.3
7
*
37510
ICD-8 Finland
Glaucoma, Chronicum simplex
+∞
7.3
7
*
Q87.27
ICD-10 Finland
CHARGE association
+∞
7.3
7
*
Q14.9
ICD-10 Finland
Congenital malformation of posterior segment of eye, unspecified
+∞
7.3
7
*
QAE40
NOMESCO Finland
Repair of anomaly or lesion after disease of skin of head or neck
10.9
7.3
13
12
Q87.09
ICD-10 Finland
Other congenital malformations that mainly affect the appearance of the face
15.8
7.2
11
7
XXA00
NOMESCO Finland
Clinical examination requiring general anaesthesia
3.7
7.2
22
60
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.3
7.2
520
4123
H65.3
ICD-10 Finland
Chronic mucoid otitis media
1.7
7.1
114
665
CG2T4
NOMESCO Finland
Topography assessment of cornea
3.6
7.1
23
65
J01FF01
ATC
clindamycin; systemic
1.3
7.1
537
4280
H52.1
ICD-10 Finland
Myopia
1.8
7.1
108
622
EP1AT
NOMESCO Finland
Punction of soft tissue of neck with ultrasound guidance
12.0
7.1
12
10
H60.0
ICD-10 Finland
Abscess of external ear
3.6
7.0
22
61
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
1.7
7.0
120
714
F82
ICD-10 Finland
Specific developmental disorder of motor function
2.8
7.0
33
118
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.3
7.0
423
3266
UGC12
NOMESCO Finland
Flexible bronchoscopy
1.7
7.0
112
655
DFF20
NOMESCO Finland
Audiometry for children
3.3
7.0
25
76
TFC99
NOMESCO Finland
Catheterisation of heart with other procedure
4.4
7.0
17
39
H26.02
ICD-10 Finland
Presenil cataract
2.4
7.0
46
195
Q21.10
ICD-10 Finland
Persistent ostium secundum
3.0
6.9
29
97
DBB00
NOMESCO Finland
Excision of lesion of external auditory canal
13.8
6.9
11
8
Z90.0
ICD-10 Finland
Acquired absence of part of head and neck
13.8
6.9
11
8
R62.0
ICD-10 Finland
Delayed milestone
2.4
6.9
46
196
F83
ICD-10 Finland
Mixed specific developmental disorders
2.4
6.9
44
184
R3120
NOMESCO Finland
Training in mobility skills
6.7
6.8
16
24
Q53.2
ICD-10 Finland
Undescended testicle, bilateral
9.3
6.8
13
14
H54.0
ICD-10 Finland
Blindness, binocular
16.7
6.7
10
6
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.5
6.7
178
1181
S01EE05
ATC
tafluprost; ophthalmic
2.2
6.7
51
230
AA1AD
NOMESCO Finland
CT of head and brain
1.3
6.7
426
3313
H02.0
ICD-10 Finland
Entropion and trichiasis of eyelid
3.0
6.6
28
94
S18
ICPC
Laceration/cut
1.2
6.6
931
8006
H52.2
ICD-10 Finland
Astigmatism
2.0
6.5
63
312
A02BC02
ATC
pantoprazole; systemic
1.2
6.5
1387
12449
ELB40
NOMESCO Finland
Partial parotidectomy
3.0
6.5
27
90
H03AA01
ATC
levothyroxine sodium; systemic
1.3
6.5
436
3416
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.7
6.5
113
677
WX725
NOMESCO Finland
Noninvasive ventilation
1.7
6.4
105
617
ZX114
NOMESCO Finland
Intramuscular
2.4
6.4
40
165
RK320, ,
NOMESCO Finland
3.9
6.4
18
46
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
3.5
6.4
21
60
DEW99
NOMESCO Finland
Other operation on mastoid and temporal bone
70.0
6.4
7
*
37520
ICD-8 Finland
Glaucoma, Secondary
70.0
6.4
7
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.2
6.4
899
7718
H40.0
ICD-10 Finland
Glaucoma suspect
1.7
6.4
115
695
R06.4
ICD-10 Finland
Hyperventilation
2.4
6.4
40
166
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
1.8
6.3
82
450
H54.7
ICD-10 Finland
Unspecified visual loss
3.6
6.3
20
56
Q10.1
ICD-10 Finland
Congenital ectropion
+∞
6.3
6
*
Q15.8
ICD-10 Finland
Other specified congenital malformations of eye
+∞
6.3
6
*
3743A
ICD-9 Finland
Other disorders of eyelids, Ptosis of eyelid[PTOSIS]
+∞
6.3
6
*
Q16.2
ICD-10 Finland
Absence of eustachian tube
+∞
6.3
6
*
3619
FHL
Other operations in this group, such as corneal refractive surgery
+∞
6.3
6
*
37400
ICD-8 Finland
Cataract, Infantilis, juvenilis
+∞
6.3
6
*
3690A
ICD-9 Finland
Blindness and low vision, Profound impairment, both eyes
+∞
6.3
6
*
3656X
ICD-9 Finland
Glaucoma associated with other ocular disorders[GLAUCOMA SECUNDARIA ALIA SEU NUD]
+∞
6.3
6
*
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
1.8
6.2
86
483
TPH07
NOMESCO Finland
Cathetrisation of artery
1.5
6.2
184
1253
M54.5
ICD-10 Finland
Low back pain
1.2
6.2
800
6805
PJD71
NOMESCO Finland
Extended sparing excision of cervical lymph nodes
6.3
6.2
15
24
31
HP
Congenital heart failure surgery
5.7
6.1
16
28
S01EE03
ATC
bimatoprost; ophthalmic
2.5
6.1
35
139
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
1.7
6.1
102
605

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
144
431
3.47
39.97
1.3
1.2
—
—
—
0
0
2475
23079
1.61
14.68
13.3
11.5
22.08
21.71
mg/l
0.21
1958
17618
42
119
3.57
12.81
8.7
6.7
—
—
—
0
0
1143
9476
1.35
12.79
8.4
7.0
1.21
1.22
mmol/l
0.35
980
8136
1052
8622
1.35
12.67
7.9
6.7
1.21
1.22
mmol/l
0.39
976
7945
2375
22100
1.49
12.53
14.4
12.4
139.56
139.56
mmol/l
0.01
2321
21469
2378
22157
1.48
12.23
14.6
12.5
3.93
3.93
mmol/l
0.35
2320
21470
984
8076
1.34
11.43
1.9
1.9
—
—
—
0
0
1391
12023
1.31
11.06
5.7
4.9
6.47
6.41
mmol/l
0.44
1284
11028
1499
13094
1.31
11.01
8.6
9.1
4.09
3.95
e9/l
1.43
1331
11413
976
8041
1.33
10.91
5.4
5.1
36.67
36.55
g/l
0.27
903
7513
1740
15570
1.31
10.42
7.1
6.8
79.16
79.54
u/l
0.11
1649
14700
1965
17919
1.32
10.04
4.3
3.9
14.66
14.52
pmol/l
1.65
1787
16475
2545
24227
1.54
9.96
12.5
10.5
—
—
—
0
0
947
7876
1.31
9.59
9.7
10.6
1.13
1.16
inr
0.92
315
2504
56
225
2.52
9.37
6.9
4.3
139.14
92.00
u/ml
0.26
20
67
349
2493
1.46
9.17
1.2
1.2
—
—
—
0
0
2488
23676
1.45
8.69
14.0
12.4
72.80
71.36
umol/l
1.20
2488
23670
2229
20844
1.34
8.60
5.1
4.5
1.91
2.02
mu/l
0.38
2079
19529
1286
11236
1.27
8.51
6.4
6.3
55.49
55.40
%
0.09
1219
10646
1359
11954
1.27
8.49
6.6
6.5
2.05
2.04
e9/l
0.04
1235
10666
1210
10498
1.27
8.48
6.7
6.6
0.67
0.66
%
0.39
1139
9889
360
2626
1.43
8.43
1.8
1.7
—
—
—
0
0
599
4745
1.33
8.42
4.3
4.1
—
—
—
0
0
1760
15975
1.27
8.41
4.0
3.9
9.60
9.85
mm/h
0.38
1644
14876
1299
11408
1.26
8.08
6.6
6.5
30.12
30.16
%
0.05
1233
10821
1350
11915
1.26
8.02
6.7
6.8
0.20
0.19
e9/l
1.08
1210
10522
2699
26222
1.77
7.77
19.4
16.8
260.81
258.68
e9/l
0.98
2649
25546
2698
26210
1.77
7.76
19.6
16.9
40.48
40.51
%
0.06
2583
24878
1239
10860
1.25
7.71
6.7
6.6
2.89
2.84
%
0.36
1171
10239
1245
10926
1.25
7.64
6.9
6.8
8.27
8.26
%
0.04
1175
10323
2700
26246
1.76
7.59
19.3
16.7
89.72
89.62
fl
0.52
2678
25916
2700
26250
1.76
7.53
19.3
16.7
29.99
29.96
pg
0.43
2679
25921
2701
26264
1.76
7.51
19.6
16.9
136.01
135.85
g/l
0.25
2680
25931
2700
26254
1.76
7.47
19.3
16.8
4.55
4.56
e12/l
0.10
2647
25521
1302
11503
1.25
7.46
6.5
6.5
0.57
0.56
e9/l
1.23
1161
10013
1302
11518
1.24
7.32
6.6
6.5
0.04
0.04
e9/l
0.02
1163
10020
2205
20719
1.30
7.30
15.4
14.0
14.28
14.43
%
0.27
2163
20356
2699
26254
1.74
7.29
19.4
16.8
6.85
6.76
e9/l
1.26
2646
25514
1154
10081
1.25
7.26
5.7
5.9
12.54
11.95
umol/l
0.35
1084
9487
653
5339
1.29
7.16
4.6
3.8
7.40
7.40
ph
0.02
130
1052
1605
14550
1.24
7.13
4.5
4.0
1259.35
1354.06
e6/l
0.03
23
175
1681
15356
1.24
6.79
4.4
3.9
—
—
—
0
0
1225
10866
1.23
6.42
7.4
6.9
—
—
—
0
0
1015
8837
1.23
6.34
2.6
2.4
74.84
72.99
nmol/l
1.30
936
8166
324
2443
1.37
6.21
1.4
1.5
—
—
—
0
0
174
1174
1.51
6.10
7.3
6.8
24.60
24.40
mmol/l
0.48
166
1137
1165
10321
1.22
6.07
2.7
2.6
—
—
—
0
0
636
5295
1.26
5.88
2.2
2.2
320.83
224.78
u/l
0.36
603
5024
356
2759
1.33
5.69
2.0
2.0
—
—
—
0
0
2480
23867
1.34
5.61
9.5
9.0
26.61
26.32
u/l
0.23
2406
23099
731
6214
1.24
5.58
2.7
2.6
57.79
70.60
u/l
0.48
685
5762
212
1517
1.43
5.53
3.7
3.3
4.65
4.66
pmol/l
0.07
188
1346
192
1352
1.45
5.46
5.4
4.7
87.13
76.17
ng/l
0.89
173
1230
485
3944
1.28
5.42
3.5
3.3
1364.03
1101.91
ng/l
0.34
400
3263
220
1597
1.41
5.31
6.9
6.2
7.39
7.41
ph
0.63
18
155
221
1610
1.40
5.22
6.9
6.2
5.25
5.11
kpa
1.73
212
1546
177
1250
1.44
4.98
7.2
6.7
—
—
—
0
0
574
4816
1.24
4.87
3.5
3.2
—
—
—
0
0
15
33
4.56
4.86
1.1
1.3
—
—
—
0
0
669
5712
1.22
4.80
5.6
7.1
—
—
—
0
0
774
6707
1.21
4.79
2.4
2.4
—
—
—
0
0
270
2065
1.34
4.73
6.0
5.9
7.37
7.37
ph
—
5
12
744
6429
1.21
4.73
3.4
3.1
42.50
46.02
ng/l
0.09
414
3599
280
2154
1.33
4.72
1.3
1.4
—
—
—
0
0
604
5113
1.23
4.70
2.4
2.3
—
—
—
0
0
264
2032
1.33
4.44
6.2
5.9
5.88
5.84
kpa
0.30
257
1978
263
2024
1.33
4.43
6.2
5.9
1.48
1.62
mmol/l
0.25
220
1643
241
1833
1.34
4.40
1.4
1.3
334.86
239.64
u/ml
0.31
218
1700
2079
19749
1.20
4.36
3.5
3.3
1.27
1.25
mmol/l
0.42
1940
18503
2104
20009
1.21
4.36
4.0
3.6
5.74
5.71
mmol/l
0.42
1935
18509
698
6043
1.21
4.30
2.9
2.6
—
—
—
0
0
350
2813
1.28
4.28
3.1
2.4
2.41
2.43
g/l
0.30
327
2605
1455
13449
1.17
4.09
3.2
3.1
—
—
—
0
0
1148
10414
1.17
4.09
9.6
9.1
0.00
0.00
e9/l
0.12
943
8477
825
7281
1.19
4.08
1.9
1.8
96.02
96.63
pmol/l
0.15
451
3964
378
3086
1.26
4.06
3.1
2.4
13.29
14.12
umol/l
1.43
356
2882
821
7250
1.19
4.03
3.0
3.3
29.98
31.45
u/l
0.67
777
6908
1244
11372
1.17
3.99
3.2
2.9
86.29
89.42
ug/l
0.29
1167
10682
608
5230
1.21
3.98
4.4
4.5
92.22
92.36
%
0.05
599
5102
323
2598
1.27
3.93
3.3
2.5
22.09
23.55
%
1.09
281
2264
328
2651
1.27
3.84
1.2
1.2
—
—
—
0
0
725
6358
1.19
3.82
3.3
3.1
2.35
2.36
mmol/l
0.14
640
5720
675
5899
1.19
3.69
3.5
3.4
7.86
8.16
mmol/l
0.83
575
5187
425
3556
1.23
3.66
2.6
2.6
137.06
113.98
ug/g
0.51
358
2812
447
3765
1.22
3.61
1.3
1.3
28.22
26.83
iu/ml
0.08
124
1135
212
1633
1.32
3.59
12.0
10.5
24.99
24.64
mmol/l
0.95
212
1625
38
199
1.92
3.53
2.7
2.2
—
—
—
0
0
227
1772
1.31
3.50
5.3
5.7
5.06
4.84
kpa
0.76
221
1721
160
1191
1.36
3.41
3.2
3.5
157.08
174.29
ng/l
0.26
142
1060
216
1681
1.31
3.41
2.1
2.1
11.22
11.65
nmol/l
0.30
199
1515
25
114
2.20
3.34
1.1
1.1
10.79
9.02
u/ml
—
5
23
1914
18204
1.16
3.34
4.9
4.6
38.31
38.19
mmol/mol
0.20
1779
17119
329
2705
1.24
3.33
9.7
7.1
1.14
1.11
mmol/l
0.66
314
2534
2157
20723
1.18
3.25
3.8
3.7
4.64
4.66
mmol/l
0.64
2032
19572
401
3382
1.22
3.19
2.7
2.7
0.99
1.21
e6/l
0.52
239
1853
2143
20588
1.17
3.18
3.8
3.6
1.44
1.46
mmol/l
1.68
2007
19355
2174
20916
1.17
3.15
4.1
3.9
2.79
2.80
mmol/l
0.22
2035
19622
646
5695
1.17
3.14
1.5
1.5
2.03
2.12
g/l
0.71
400
3481
33
172
1.93
3.14
5.8
9.6
12.51
11.35
%
1.03
33
172
89
606
1.48
3.14
2.3
2.6
363.63
399.60
ug/l
0.10
83
559
520
4507
1.19
3.09
3.8
3.4
417.81
281.11
mg/l
0.28
355
3005
542
4723
1.18
3.02
4.4
4.0
11.37
13.74
mg/mmol
0.21
363
3106
233
1863
1.27
3.01
10.9
9.3
—
—
—
0
0
381
3216
1.21
3.01
2.8
2.8
3.71
3.01
e6/l
0.61
219
1689
837
7552
1.15
2.99
4.0
3.6
83.75
80.86
e6/l
0.04
583
5076
547
4779
1.18
2.96
2.0
2.2
1.13
1.04
mg/l
0.23
398
3498
192
1502
1.30
2.95
1.5
1.5
18.66
19.69
iu/l
0.19
152
1212
111
799
1.41
2.94
9.4
10.4
1.38
1.26
mg/l
0.87
103
763
203
1605
1.29
2.88
4.4
4.1
0.42
0.62
%
1.37
68
480
729
6527
1.16
2.88
1.4
1.4
1.58
1.79
u/ml
0.19
191
1670
42
245
1.72
2.83
1.5
1.3
—
—
nmol/l
—
0
0
48
292
1.65
2.78
1.8
1.7
68.05
70.83
mmol/l
0.18
37
249
214
1713
1.27
2.76
5.1
3.7
—
—
—
0
0
203
1621
1.27
2.68
10.1
9.0
96.25
95.70
%
0.69
191
1563
208
1666
1.27
2.68
4.8
4.4
0.05
0.11
%
1.27
66
480
692
6206
1.15
2.65
3.6
3.2
45.53
65.28
e6/l
0.55
536
4699
287
2387
1.23
2.64
3.0
3.4
7.79
7.29
umol/l
0.10
246
2027
1639
15550
1.13
2.59
3.1
3.0
38.78
39.29
u/l
0.10
1552
14770
348
2957
1.20
2.58
2.9
3.2
29.52
29.87
s
0.66
341
2867
355
3023
1.20
2.57
5.3
5.0
0.81
0.82
mmol/l
0.50
335
2866
27
142
1.91
2.55
2.2
3.4
31.55
39.84
mg/l
0.20
21
107
12
44
2.73
2.54
1.7
1.3
—
—
—
0
0
655
5870
1.15
2.53
4.1
3.5
0.00
0.00
estimate
1.49
232
2163
116
865
1.36
2.52
14.7
11.8
—
—
—
0
0
10
31
3.23
2.51
1.1
1.5
—
—
—
0
0
148
1146
1.31
2.50
1.7
1.6
8.98
8.40
u/l
0.19
116
896
42
255
1.66
2.48
1.3
1.3
0.43
0.39
g/l
0.25
32
176
42
255
1.66
2.48
1.3
1.3
2.89
2.79
g/l
0.14
32
179
42
255
1.66
2.48
1.3
1.3
6.69
6.54
g/l
0.09
32
180
218
1773
1.25
2.48
11.5
9.3
7.52
7.66
mmol/l
0.14
212
1712
53
342
1.56
2.46
4.6
3.3
—
—
—
0
0
180
1435
1.27
2.43
1.2
1.2
—
—
—
0
0
124
940
1.33
2.43
2.7
3.9
21.60
21.85
s
0.24
109
826
191
1536
1.26
2.41
1.4
1.4
—
—
—
0
0
250
2076
1.22
2.36
2.2
2.3
7045.69
7048.14
u/l
0.00
106
796
42
260
1.62
2.32
1.3
1.3
—
—
—
0
0
255
2126
1.22
2.32
4.2
3.7
32.14
32.03
%
0.06
187
1557
464
4080
1.16
2.31
1.6
1.5
20.61
20.13
nmol/l
0.30
402
3564
196
1590
1.25
2.30
5.0
4.5
0.00
0.33
%
0.84
55
396
429
3751
1.17
2.30
1.6
1.6
50535213.30
40668343.85
pmol/l
0.10
374
3204
224
1846
1.23
2.28
2.8
2.9
10.36
10.24
g/l
0.11
209
1710
212
1739
1.24
2.26
4.8
4.4
0.79
0.89
%
0.23
71
551
408
3558
1.17
2.26
1.3
1.2
10.84
10.23
u/ml
0.06
161
1421
599
5375
1.15
2.26
2.4
2.3
2.81
2.79
mg/l
0.06
521
4640
1176
11002
1.12
2.25
3.8
3.3
0.00
0.00
estimate
1.47
243
2277
243
2025
1.22
2.23
1.2
1.2
144.75
155.45
iu/ml
0.17
102
753
5
9
5.56
2.21
4.2
3.1
—
—
—
0
0
75
533
1.42
2.21
7.6
7.3
1.17
1.24
mmol/l
0.43
65
460
126
973
1.31
2.20
7.0
7.7
25.21
24.26
mmol/l
2.16
116
923
43
272
1.59
2.20
2.2
3.0
1.17
1.35
e9/l
0.81
32
236
341
2937
1.18
2.20
1.8
1.7
1078.80
1182.49
nmol/l
1.36
262
2267
383
3333
1.17
2.18
3.9
3.3
977.24
466.86
ng/l
0.48
238
2163
1173
10987
1.12
2.17
5.1
4.5
0.00
0.00
estimate
0.50
237
2227
26
144
1.81
2.14
1.8
3.3
336.43
298.63
e6/l
0.15
14
95
482
4276
1.15
2.13
3.1
2.6
10.71
7.20
e6/l
0.45
422
3836
116
890
1.32
2.13
1.7
1.6
—
—
—
0
0
40
251
1.60
2.12
1.6
1.3
—
—
—
0
0
86
632
1.37
2.10
1.8
2.0
3.69
4.74
iu/l
0.80
30
236
972
9028
1.12
2.08
3.5
3.0
5.95
5.99
ph
0.18
82
870
219
1823
1.22
2.05
9.9
8.4
1.22
0.93
mmol/l
0.57
168
1414
630
5707
1.13
2.05
3.4
3.1
0.57
0.34
e6/l
0.92
482
4272
244
2056
1.20
2.02
4.4
3.7
1.76
1.69
%
0.33
221
1863
1179
11082
1.11
2.00
3.8
3.3
0.00
0.00
estimate
0.80
231
2157
31
186
1.67
1.97
1.2
1.1
—
—
—
0
0
7
21
3.34
1.96
2.7
3.1
—
—
—
0
0
63
445
1.43
1.95
7.0
3.6
—
—
—
0
0
38
241
1.58
1.95
1.6
4.1
—
—
—
0
0
62
437
1.43
1.95
8.0
4.0
2.03
2.28
mmol/l
0.26
42
267
62
437
1.43
1.95
8.0
4.0
9.02
9.04
kpa
0.04
62
431
62
438
1.42
1.92
8.0
4.0
5.05
4.95
kpa
0.59
62
432
262
2235
1.19
1.91
2.4
2.1
359.87
373.79
nmol/l
0.50
242
2072
464
4146
1.14
1.86
4.5
4.3
2.16
2.18
ug/l
0.03
410
3747
132
1052
1.27
1.86
5.6
4.5
130.51
130.91
g/l
0.07
127
1029
181
1496
1.22
1.84
9.8
9.1
123.33
123.39
g/l
0.01
172
1455
59
418
1.42
1.82
1.3
1.2
—
—
—
0
0
106
826
1.29
1.79
5.2
4.4
1.31
1.28
%
0.11
106
821
516
4661
1.13
1.75
2.8
2.6
2144.23
4362.20
umol/l
0.94
473
4175
50
347
1.45
1.73
9.6
9.4
10.64
11.49
mmol/l
0.95
42
311
50
348
1.44
1.71
9.6
9.4
104.93
105.32
mmol/l
0.24
42
312
452
4057
1.14
1.70
3.3
2.8
542.82
553.34
mosm/kgh2o
0.40
386
3513
37
243
1.53
1.68
5.3
7.8
10.85
10.57
mg/l
0.16
32
226
57
411
1.39
1.62
5.7
6.0
—
—
—
0
0
620
5689
1.12
1.61
3.4
3.0
—
—
—
0
0
5
14
3.58
1.61
1.0
1.1
—
—
—
0
0
27
166
1.63
1.61
1.3
1.3
181.09
229.53
pmol/l
0.38
27
166
215
1835
1.19
1.60
10.0
8.3
12.77
12.94
kpa
0.18
205
1759
215
1835
1.19
1.60
10.0
8.3
5.17
5.10
kpa
0.60
204
1757
809
7534
1.10
1.59
2.2
2.1
—
—
—
0
0
555
5068
1.12
1.58
3.6
3.2
—
—
—
0
0
113
907
1.26
1.54
1.3
1.2
0.24
1.06
u/ml
—
10
77
34
224
1.52
1.54
2.1
3.1
0.22
0.20
e9/l
0.29
23
187
7
160
0.44
1.53
1.4
1.8
—
—
—
0
0
80
615
1.31
1.53
7.1
6.5
0.92
0.91
%
0.08
72
574
173
1458
1.20
1.49
5.0
3.5
1.22
1.23
mmol/l
0.69
155
1254
34
227
1.50
1.46
2.1
3.1
373.87
544.18
e6/l
1.85
23
187
47
335
1.41
1.45
1.4
1.4
—
—
—
0
0
19
110
1.73
1.42
2.2
1.9
—
—
—
0
0
194
1660
1.18
1.42
10.3
8.0
1.47
1.38
mmol/l
0.47
189
1617
26
165
1.58
1.40
1.4
1.2
—
—
—
0
0
9
40
2.25
1.40
1.4
1.1
—
—
—
0
0
27
173
1.57
1.40
2.8
2.1
—
—
—
0
0
160
1349
1.20
1.39
1.4
1.4
—
—
—
0
0
126
1038
1.22
1.39
12.2
10.2
94.21
94.06
%
0.10
126
1032
170
1442
1.19
1.38
4.6
3.3
79.40
70.98
e9/l
1.36
134
1055
2150
21003
1.10
1.38
15.6
14.4
333.51
333.51
g/l
0.00
2138
20827
79
617
1.29
1.37
7.0
6.5
1.59
1.61
%
0.11
71
574
31
208
1.50
1.32
1.7
1.7
58.65
56.35
%
0.11
20
139
57
428
1.34
1.32
1.2
1.1
31.34
1145.50
iu/ml
0.59
19
126
28
184
1.53
1.31
2.7
3.4
—
—
—
0
0
9
43
2.10
1.30
1.0
12.5
—
—
—
0
0
31
209
1.49
1.30
1.5
1.4
1.33
1.23
promille
0.14
23
163
176
1510
1.18
1.28
2.1
2.5
4.19
5.41
e9/l
1.58
153
1299
57
431
1.33
1.27
2.3
2.4
128.21
132.50
g/l
0.68
43
333
167
1429
1.18
1.25
2.3
1.8
1.37
1.31
g/l
0.09
158
1335
121
1006
1.21
1.24
6.1
5.6
—
—
—
0
0
413
3764
1.11
1.23
1.8
1.6
—
—
—
0
0
25
163
1.54
1.23
1.0
1.0
—
—
—
0
0
102
838
1.23
1.19
2.1
2.3
—
—
—
0
0
527
4876
1.10
1.18
4.1
3.5
1.02
1.02
kg/l
0.11
76
711
19
117
1.63
1.18
2.4
4.2
204.25
157.94
umol/l
0.19
12
66
213
1869
1.15
1.17
2.4
2.8
0.22
0.22
g/l
0.52
208
1759
221
1946
1.15
1.16
2.1
2.4
33.23
62.72
u/l
0.62
202
1643
256
2279
1.14
1.15
1.3
1.4
—
—
—
0
0
90
1098
0.81
1.15
1.4
1.5
—
—
—
0
0
23
150
1.54
1.14
1.5
1.6
23.79
34.12
%
0.84
14
97
52
396
1.32
1.13
1.3
1.6
0.84
0.76
g/l
0.17
39
302
175
1519
1.16
1.12
1.6
1.6
370.05
307.04
mu/l
1.23
159
1353
61
476
1.29
1.11
1.2
1.2
—
—
—
0
0
19
119
1.60
1.11
1.9
3.0
1055.95
1195.17
u/ml
0.12
19
119
17
104
1.64
1.09
1.4
1.2
—
—
—
0
0
5
21
2.38
1.09
1.8
1.2
38.06
14.06
nmol/l
—
5
21
21
136
1.55
1.08
1.0
1.1
—
—
—
0
0
81
658
1.24
1.07
5.5
4.9
—
—
—
0
0
97
804
1.21
1.06
1.2
1.2
—
—
—
0
0
146
1257
1.17
1.05
2.1
2.3
7.27
7.27
ug/l
0.00
119
1121
7
33
2.12
1.05
1.0
1.1
—
—
—
0
0
66
526
1.26
1.04
1.9
2.1
10.66
10.53
mg/l
0.05
58
494
91
1095
0.83
1.03
1.4
1.5
—
—
—
0
0
9
46
1.96
1.03
2.0
1.1
—
—
—
0
0
7
34
2.06
1.02
1.0
2.0
—
—
—
0
0
669
6296
1.08
1.02
3.3
2.9
—
—
—
0
0
163
1421
1.16
1.01
1.1
1.2
—
—
—
0
0
35
257
1.37
0.98
1.5
1.5
—
—
—
0
0
7
135
0.52
0.98
4.3
2.1
—
—
—
0
0
74
603
1.23
0.97
1.9
2.0
1.15
1.82
ug/l
0.40
64
535
32
232
1.38
0.97
3.0
4.0
—
—
—
0
0
0
30
0.00
0.97
0.0
1.2
—
8.88
—
0
6
62
496
1.26
0.96
3.0
2.5
—
—
—
0
0
335
3066
1.11
0.96
2.7
2.7
2.43
2.43
mmol/l
0.12
284
2682
10
173
0.58
0.95
1.6
1.6
—
—
—
0
0
859
8185
1.07
0.94
2.3
2.4
—
—
—
0
0
262
2370
1.12
0.94
1.2
1.2
—
—
—
0
0
19
125
1.52
0.93
2.7
2.3
2.09
2.64
u/field
0.25
11
66
95
1125
0.84
0.93
1.5
1.5
—
—
—
0
0
23
158
1.46
0.93
1.3
1.3
96.13
75.93
umol/l
0.38
23
158
16
101
1.59
0.93
5.6
4.2
—
—
—
0
0
8
143
0.56
0.93
1.0
1.1
—
—
—
0
0
8
144
0.55
0.93
1.0
1.3
1.65
1.55
g/l
—
8
144
164
1442
1.15
0.92
1.2
1.3
37.69
45.17
au/ml
—
8
73
14
220
0.63
0.91
1.6
1.5
—
—
—
0
0
22
312
0.70
0.88
1.5
3.0
—
—
—
0
0
346
3193
1.10
0.85
1.4
1.4
428.75
514.78
titre
0.43
64
621
93
788
1.19
0.85
4.3
4.2
0.23
0.32
g/l
0.62
50
409
106
909
1.17
0.85
1.1
1.2
0.77
3.09
u/ml
4.36
67
524
23
163
1.41
0.82
1.0
1.2
1.07
1.05
ratio
—
9
69
48
382
1.26
0.81
1.4
1.5
7.37
6.83
mmol/l
0.63
41
346
0
25
0.00
0.79
0.0
1.2
—
—
—
0
0
12
74
1.62
0.78
2.3
2.3
—
—
—
0
0
32
243
1.32
0.77
1.3
1.2
—
—
—
0
0
6
34
1.77
0.76
2.5
1.9
—
—
—
0
0
86
733
1.18
0.76
1.6
1.8
0.22
0.23
g/l
0.19
79
692
9
53
1.70
0.75
2.6
5.9
—
—
—
0
0
65
774
0.84
0.72
1.9
1.5
199.54
219.24
u/ml
0.32
44
446
18
125
1.44
0.72
2.2
2.0
113.40
100.52
umol/l
—
5
25
18
125
1.44
0.72
1.0
1.0
8.06
18.84
u/ml
1.71
12
77
7
39
1.80
0.72
4.0
2.7
—
—
—
0
0
13
84
1.55
0.71
1.2
1.2
—
—
—
0
0
29
220
1.32
0.71
1.1
1.0
—
—
—
0
0
11
69
1.60
0.68
1.7
1.4
—
—
—
0
0
29
222
1.31
0.68
1.3
1.2
—
—
—
0
0
155
1393
1.12
0.67
2.8
4.2
10.75
19.80
ug/l
0.54
115
1101
5
92
0.54
0.67
1.0
1.1
37.71
8.81
u/ml
—
5
77
106
931
1.14
0.66
1.6
1.7
—
—
—
0
0
44
357
1.24
0.66
1.5
1.6
—
—
—
0
0
5
28
1.79
0.66
4.0
4.8
—
—
—
0
0
7
44
1.59
0.65
1.0
1.1
—
—
—
0
0
7
44
1.59
0.65
1.0
1.1
—
—
—
0
0
7
44
1.59
0.65
1.0
1.1
—
—
—
0
0
52
623
0.83
0.64
1.2
1.4
—
1287.78
—
0
18
90
785
1.15
0.63
1.1
1.1
4.31
2.56
u/ml
0.46
56
464
11
165
0.67
0.63
1.3
1.5
0.92
0.96
g/l
0.18
11
165
41
333
1.23
0.62
3.1
3.8
—
—
—
0
0
38
306
1.24
0.62
2.2
1.3
—
—
—
0
0
96
843
1.14
0.61
1.1
1.1
4.82
6.42
u/ml
0.49
57
510
28
217
1.29
0.61
1.6
2.0
—
—
—
0
0
29
227
1.28
0.60
2.2
1.7
288.52
285.54
mosm/kgh2o
0.26
23
177
260
2416
1.08
0.59
2.8
2.8
0.72
0.72
ug/l
0.01
152
1444
86
752
1.15
0.59
1.2
1.2
—
—
—
0
0
76
659
1.16
0.58
1.3
1.2
—
—
—
0
0
54
455
1.19
0.58
1.3
1.4
17.88
18.73
u/l
0.08
46
390
19
140
1.36
0.58
1.2
1.3
3496.27
2268.77
e6/l
0.45
11
95
17
123
1.38
0.57
1.2
1.4
22596.25
83746.46
e6/l
—
8
71
6
36
1.67
0.56
1.0
1.0
44.77
14.53
u/ml
—
6
28
86
756
1.14
0.56
1.6
1.8
1.14
1.18
g/l
0.55
80
713
5
88
0.57
0.56
1.0
1.1
—
—
—
0
0
171
1567
1.10
0.55
2.2
2.3
15.62
22.89
au/ml
—
6
137
101
900
1.13
0.54
1.9
2.9
—
—
—
0
0
125
1129
1.11
0.53
1.3
1.4
—
—
—
0
0
11
74
1.49
0.53
1.2
1.2
—
—
—
0
0
11
74
1.49
0.53
1.7
1.6
—
—
—
0
0
124
1370
0.90
0.53
1.4
1.4
—
—
—
0
0
6
39
1.54
0.53
1.3
1.1
55.00
32.24
%
—
6
33
619
5952
1.05
0.51
1.8
1.7
—
—
—
0
0
46
388
1.19
0.51
2.9
2.7
16.29
16.93
%
0.52
27
201
15
109
1.38
0.50
1.2
1.4
—
—
—
0
0
13
92
1.41
0.50
1.3
1.2
—
—
—
0
0
71
622
1.14
0.50
5.8
9.0
—
—
—
0
0
36
297
1.21
0.50
1.9
2.0
1.64
1.67
mmol/l
0.06
36
292
6
41
1.46
0.50
1.0
1.3
3.00
2.93
%
—
6
33
533
5111
1.05
0.49
1.6
1.6
1.39
1.37
mmol/l
0.23
466
4427
7
46
1.52
0.48
1.0
1.0
—
—
—
0
0
7
46
1.52
0.48
1.3
1.3
41.43
58.25
%
—
7
36
24
300
0.80
0.47
5.0
3.5
—
—
—
0
0
45
383
1.18
0.46
4.6
3.8
—
—
—
0
0
21
164
1.28
0.46
1.3
1.2
—
—
—
0
0
73
647
1.13
0.45
2.4
2.8
4.58
6.18
umol/l
1.32
53
498
90
809
1.12
0.44
1.1
1.1
1.08
1.20
u/ml
0.10
46
421
44
377
1.17
0.43
1.6
1.7
—
—
—
0
0
9
130
0.69
0.43
2.2
3.4
—
—
—
0
0
5
31
1.61
0.43
2.0
8.3
—
—
—
0
0
5
31
1.61
0.43
1.2
1.2
—
226.40
—
0
5
52
452
1.15
0.43
1.2
1.2
—
—
—
0
0
64
565
1.14
0.42
1.3
1.5
0.34
0.40
nmol/l
0.28
52
467
0
16
0.00
0.41
0.0
1.6
—
350.94
—
0
16
8
59
1.36
0.41
3.5
2.0
—
—
—
0
0
15
114
1.32
0.40
1.3
1.8
0.73
1.34
nmol/l
—
9
91
513
4944
1.05
0.40
1.8
1.8
—
—
—
0
0
5
34
1.47
0.40
1.2
1.0
—
—
—
0
0
22
177
1.24
0.40
1.0
1.2
5.38
22.32
u/ml
0.52
15
121
5
35
1.43
0.39
2.8
6.8
91.76
28.58
ug/min
—
5
25
7
106
0.66
0.39
1.1
1.3
124.43
164.85
mmol/24h
—
7
106
0
19
0.00
0.39
0.0
1.4
—
8.00
—
0
10
0
19
0.00
0.39
0.0
1.3
—
—
—
0
0
11
80
1.38
0.38
1.3
2.7
—
—
—
0
0
62
552
1.13
0.38
1.3
2.3
—
—
—
0
0
55
620
0.88
0.37
1.2
1.4
53.33
87.42
titre
—
6
62
97
887
1.10
0.37
3.4
3.0
—
—
—
0
0
18
143
1.26
0.36
2.9
2.7
—
—
—
0
0
21
171
1.23
0.35
1.5
1.7
24.73
23.78
umol/l
0.05
21
161
11
82
1.34
0.34
1.3
1.4
—
—
—
0
0
164
1541
1.07
0.33
1.4
1.6
—
—
—
0
0
19
154
1.24
0.33
1.0
1.1
1548.74
1459.29
miu/ml
0.14
19
154
16
127
1.26
0.33
1.1
1.4
—
—
—
0
0
15
118
1.27
0.33
1.8
1.5
0.28
2.73
u/ml
2.58
15
118
13
166
0.78
0.33
1.4
1.3
—
—
—
0
0
6
87
0.69
0.33
1.2
1.1
—
—
—
0
0
35
303
1.16
0.32
1.4
1.6
—
—
—
0
0
184
1738
1.06
0.32
1.3
1.3
—
—
—
0
0
194
2048
0.94
0.32
1.7
2.1
—
—
—
0
0
64
579
1.11
0.31
2.1
3.1
—
—
—
0
0
7
53
1.32
0.30
1.3
1.4
—
—
—
0
0
7
54
1.30
0.30
1.3
2.4
1.79
3.18
nmol/l
—
7
49
12
93
1.29
0.30
3.3
2.7
—
—
—
0
0
135
1268
1.07
0.29
1.3
1.3
202.32
227.55
miu/ml
0.35
58
626
8
108
0.74
0.29
1.0
1.4
—
—
—
0
0
243
2326
1.05
0.28
1.5
1.5
—
—
—
0
0
18
149
1.21
0.27
1.4
1.3
71.67
73.91
%
0.37
18
143
15
183
0.82
0.27
3.3
2.9
48524.73
40099.67
ug/l
0.59
15
183
8
64
1.25
0.27
1.3
1.2
—
—
—
0
0
17
140
1.22
0.27
2.6
2.6
35.12
43.85
%
—
10
73
38
427
0.89
0.27
1.1
1.1
—
—
—
0
0
71
653
1.09
0.27
1.3
2.1
389.48
472.36
mg/l
2.47
66
618
14
113
1.24
0.26
1.3
1.3
—
—
—
0
0
216
2071
1.05
0.25
4.5
3.5
—
—
—
0
0
200
2087
0.95
0.24
1.7
2.1
—
—
—
0
0
105
1116
0.94
0.24
1.1
1.1
—
—
—
0
0
200
2084
0.96
0.23
1.7
2.1
—
—
—
0
0
39
432
0.90
0.23
1.1
1.1
—
—
—
0
0
60
553
1.09
0.23
1.4
1.4
255.33
308.91
ug/g
0.84
27
298
33
295
1.12
0.22
1.5
1.2
0.92
3.31
u/ml
1.51
17
146
199
2070
0.96
0.22
1.7
2.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
5
43
1.16
0.21
2.6
1.9
—
—
—
0
0
28
249
1.13
0.20
1.1
1.1
0.67
3.33
u/ml
0.85
15
96
17
145
1.17
0.20
1.3
1.0
19.89
19.33
mmol/l
0.27
17
137
17
145
1.17
0.20
1.4
1.4
735.29
379.04
mu/l
1.14
17
139
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.9
—
—
—
0
0
47
432
1.09
0.20
3.6
3.3
19.61
23.64
mg/l
0.50
31
260
63
587
1.07
0.19
1.3
2.2
9.74
22.30
e6/l
0.88
46
445
6
50
1.20
0.19
1.2
1.2
—
—
—
0
0
43
394
1.09
0.19
1.6
1.7
18408.68
11849.81
e6/l
0.34
28
291
14
165
0.85
0.19
1.1
1.1
—
—
—
0
0
11
90
1.22
0.19
1.0
1.3
—
—
—
0
0
63
588
1.07
0.19
1.4
2.3
1162.16
7901.26
e6/l
0.53
49
466
70
746
0.94
0.19
2.6
2.0
1.41
1.38
g/l
0.07
56
656
156
1498
1.04
0.19
4.2
3.3
—
—
—
0
0
30
270
1.11
0.18
1.6
1.7
—
—
—
0
0
16
137
1.17
0.18
1.0
1.0
—
—
—
0
0
19
166
1.15
0.18
2.6
2.4
—
—
—
0
0
41
377
1.09
0.17
2.6
2.5
—
—
—
0
0
142
1364
1.04
0.17
2.9
2.5
—
—
—
0
0
46
495
0.93
0.16
1.3
1.2
10.46
37.51
u/ml
—
10
46
782
7713
1.02
0.16
1.6
1.7
—
—
—
0
0
26
234
1.11
0.16
1.2
1.2
—
—
—
0
0
131
1259
1.04
0.16
3.0
2.7
67.39
66.93
g/l
0.24
118
1170
159
1646
0.96
0.16
1.6
2.2
—
—
—
0
0
60
564
1.07
0.16
1.1
1.1
—
—
—
0
0
28
254
1.10
0.16
1.7
1.9
—
—
—
0
0
140
1450
0.96
0.15
2.1
2.9
—
—
—
0
0
60
566
1.06
0.14
1.1
1.1
—
—
—
0
0
13
112
1.16
0.14
1.2
1.1
—
—
—
0
0
173
1782
0.97
0.14
1.4
1.4
—
—
—
0
0
12
103
1.17
0.13
1.2
1.1
—
—
—
0
0
90
939
0.96
0.13
1.1
1.1
—
—
—
0
0
9
107
0.84
0.13
1.1
1.5
134.22
135.57
nmol/l
—
9
107
25
273
0.91
0.13
1.5
1.4
—
—
—
0
0
23
252
0.91
0.12
1.3
1.2
22.69
39.11
mg/l
4.94
16
205
12
104
1.15
0.12
1.0
1.0
—
—
—
0
0
140
1443
0.97
0.12
1.6
1.4
—
—
—
0
0
93
966
0.96
0.12
3.1
2.3
—
—
—
0
0
299
2933
1.02
0.12
1.3
1.3
—
—
—
0
0
27
292
0.92
0.11
1.4
2.4
—
—
—
0
0
52
493
1.06
0.11
3.6
2.2
9.96
10.32
g/l
0.18
41
449
37
347
1.07
0.11
1.3
1.3
—
—
—
0
0
14
124
1.13
0.11
2.6
1.7
3.07
3.54
mg/l
0.36
14
119
42
396
1.06
0.11
2.2
2.5
82.83
117.01
ug/min
0.23
24
257
23
211
1.09
0.11
2.3
3.4
—
—
—
0
0
19
173
1.10
0.10
1.2
1.2
—
—
—
0
0
19
173
1.10
0.10
1.2
1.2
—
—
—
0
0
48
456
1.05
0.10
1.2
1.1
2.58
2.39
u/ml
0.08
21
213
27
290
0.93
0.10
1.3
1.2
1.01
11.51
u/ml
1.19
12
123
23
212
1.09
0.10
1.1
1.0
—
—
—
0
0
276
2808
0.98
0.10
1.8
1.9
—
—
—
0
0
5
44
1.14
0.10
1.0
1.7
—
—
—
0
0
56
585
0.96
0.09
1.3
1.2
3.44
11.50
u/ml
—
8
95
16
176
0.91
0.09
1.3
1.2
—
—
—
0
0
190
1938
0.98
0.09
1.7
2.2
—
—
—
0
0
63
654
0.96
0.08
2.0
1.6
—
—
—
0
0
76
736
1.03
0.08
1.1
1.2
—
—
—
0
0
6
72
0.83
0.07
1.8
2.8
—
—
—
0
0
8
77
1.04
0.07
1.0
1.9
—
—
—
0
0
8
77
1.04
0.07
2.3
1.3
—
—
—
0
0
7
81
0.86
0.07
1.6
1.6
—
—
—
0
0
7
83
0.84
0.07
1.0
1.1
—
—
—
0
0
9
84
1.07
0.07
1.0
1.3
—
—
—
0
0
9
85
1.06
0.07
1.0
1.5
64.00
93.72
nmol/24h
—
9
85
8
95
0.84
0.06
1.5
2.0
—
—
—
0
0
56
579
0.97
0.06
1.3
1.2
2.24
2.86
u/ml
—
5
61
14
152
0.92
0.06
1.3
1.2
—
—
—
0
0
30
314
0.95
0.05
1.0
1.1
1.44
1.47
g/l
0.23
30
282
39
405
0.96
0.05
1.2
1.3
2.87
4.67
u/ml
1.13
15
174
51
495
1.03
0.05
1.6
1.6
—
—
—
0
0
44
426
1.03
0.05
3.2
2.2
40.15
38.33
g/l
1.70
33
383
43
444
0.97
0.05
1.4
1.2
—
—
—
0
0
12
130
0.92
0.04
1.2
1.5
—
—
—
0
0
61
625
0.98
0.04
2.0
1.6
90.00
105.79
u/ml
0.63
11
101
60
586
1.02
0.04
1.2
2.1
3.76
3.60
mmol/l
0.49
53
554
63
617
1.02
0.03
1.1
1.1
3.58
5.10
u/ml
0.40
32
325
19
181
1.05
0.03
2.4
2.7
1.93
1.49
g/24h
—
9
101
19
199
0.95
0.03
21.8
20.6
1249.47
1402.37
nmol/l
0.49
19
193
33
320
1.03
0.03
1.8
1.6
—
—
—
0
0
10
108
0.93
0.03
1.4
1.3
163.50
396.14
u/l
—
10
94
54
551
0.98
0.03
2.3
2.2
—
—
—
0
0
414
4120
1.01
0.03
1.5
1.5
—
—
—
0
0
25
241
1.04
0.02
1.1
1.1
10.40
10.05
iu/ml
—
5
53
18
188
0.96
0.02
1.2
1.1
—
—
—
0
0
19
198
0.96
0.02
16.3
14.4
680.63
811.68
nmol/l
0.76
19
190
58
571
1.02
0.02
1.1
1.1
4.08
7.15
u/ml
0.98
26
267
15
143
1.05
0.01
1.1
1.1
—
—
—
0
0
20
207
0.97
0.01
1.1
1.1
—
—
—
0
0
13
136
0.96
0.00
1.6
2.4
21.78
260.32
ug/l
0.69
13
118
11
113
0.97
0.00
1.0
1.1
327.91
212.42
iu/ml
0.26
11
113
15
155
0.97
0.00
1.0
1.0
—
—
—
0
0
42
420
1.00
0.00
1.0
1.1
—
—
—
0
0
53
531
1.00
0.00
2.9
3.5
2460.78
2729.97
u/ml
0.04
46
449
15
154
0.97
0.00
1.5
1.4
17324.00
77187.41
e6/l
—
10
105
20
205
0.98
0.00
1.6
1.6
—
—
—
0
0
18
177
1.02
0.00
1.1
1.2
—
—
—
0
0
13
134
0.97
0.00
1.5
1.1
—
—
—
0
0
16
161
0.99
0.00
2.6
3.9
—
—
—
0
0
53
526
1.01
0.00
1.0
1.1
0.39
0.46
u/ml
0.07
16
186
39
390
1.00
0.00
5.3
3.4
62.02
63.84
mg/l
0.02
26
309
39
390
1.00
0.00
5.3
3.4
45.09
39.63
mg/l
0.10
26
310
22
215
1.02
0.00
1.3
1.3
0.95
4.87
u/ml
2.46
14
121
17
170
1.00
0.00
1.1
1.4
1.47
1.44
nmol/l
0.04
17
154
58
580
1.00
0.00
1.4
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
6
68
0.88
0.00
1.2
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
6
68
0.88
0.00
1.2
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
6.3
—
138.29
—
0
7
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
6
68
0.88
0.00
2.0
2.4
—
—
—
0
0
6
60
1.00
0.00
5.3
4.9
1.19
1.20
mmol/l
—
6
55
6
68
0.88
0.00
1.2
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
7
71
0.99
-0.00
5.3
2.9
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.0
—
—
—
0
0
5
57
0.88
-0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
133.04
—
0
5
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
2.56
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
16.83
—
0
6
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
99
0.91
-0.00
3.9
2.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
0.04
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
0.06
—
0
8
9
99
0.91
-0.00
7.8
5.4
—
—
—
0
0
5
55
0.91
-0.00
1.0
1.0
166.20
164.56
g/l
—
5
55
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.6
—
1.92
—
0
5
0
5
0.00
-0.00
0.0
3.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint Q17_CONGEN_MALFO_EYE_EAR_FACE_NECK and mortality.

Females

Parameter HR [95% CI] p-value
Q17_CONGEN_MALFO_EYE_EAR_FACE_NECK 1.228 [1.05, 1.43] 0.01
Birth year 0.989 [0.98, 1.0] 0.01

During the follow-up period (1.1.1998 — 31.12.2019), 596 out of 19221 females with Q17_CONGEN_MALFO_EYE_EAR_FACE_NECK died.

Males

Parameter HR [95% CI] p-value
Q17_CONGEN_MALFO_EYE_EAR_FACE_NECK 1.217 [1.07, 1.39] 0.003
Birth year 0.989 [0.98, 1.0] 0.014

During the follow-up period (1.1.1998 — 31.12.2019), 742 out of 18380 males with Q17_CONGEN_MALFO_EYE_EAR_FACE_NECK died.

Mortality risk

Mortality risk for people of age

years, who have Q17_CONGEN_MALFO_EYE_EAR_FACE_NECK.

N-year risk Females Males
1 0.12% 0.234%
5 0.592% 1.33%
10 1.52% 3.435%
15 2.831% 6.677%
20 4.722% 12.141%

Relationships between endpoints

Index endpoint: Q17_CONGEN_MALFO_EYE_EAR_FACE_NECK – Congenital malformations of eye, ear, face and neck

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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