No definition available.
Congenital malformations of eye, ear, face and neck
EFO MESH Endpoint Browser PheWeb
Q17_CONGEN_MALFO_EYE_EAR_FACE_NECK
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
2740 |
4. Check minimum number of eventsNone |
2740 |
5. Include endpoints |
2740 |
6. Filter based on genotype QC (FinnGen only) |
2740 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 2
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- Q
- Name in latin
- Malformationes congenitae oculorum, aurium, faciei et colli
Similar endpoints
↥List of similar endpoints to
Congenital malformations of eye, ear, face and neck
based on the number of shared cases.
Similar with more cases:
- Congenital malformations, deformations and chromosomal abnormalities
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 42386 | 21671 | 20654 |
| Only index persons | 33417 | 17407 | 16010 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.60 | 0.62 | 0.58 |
| Only index persons | 0.63 | 0.64 | 0.61 |
| Median age at first event (years) | |||
| Whole population | 6.75 | 7.53 | 5.86 |
| Only index persons | 11.62 | 13.48 | 9.60 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2740 | 1739 | 1001 |
| Unadjusted period prevalence (%) | 0.54 | 0.59 | 0.44 |
| Median age at first event (years) | 31.42 | 27.92 | 37.51 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 2489
- Matched controls
- 24888
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q18.0
ICD-10 Finland
Sinus, fistula and cyst of branchial cleft
3796.5
323.0
608
*
ENB40
NOMESCO Finland
Excision of branchial cyst or fistula
1441.4
323.0
369
*
DAD30
NOMESCO Finland
Plastic repair of auricle
928.4
323.0
324
*
Q17.5
ICD-10 Finland
Prominent ear
3956.3
323.0
353
*
Q18.8
ICD-10 Finland
Other specified congenital malformations of face and neck
+∞
315.5
296
*
Q13.2
ICD-10 Finland
Other congenital malformations of iris
+∞
239.5
226
*
Q18.1
ICD-10 Finland
Preauricular sinus and cyst
1781.6
167.6
161
*
Q10.5
ICD-10 Finland
Congenital stenosis and stricture of lacrimal duct
555.8
159.8
157
*
Q12.0
ICD-10 Finland
Congenital cataract
+∞
155.9
148
*
ENB50
NOMESCO Finland
Excision of cyst or fistula of thyroglossic duct
767.6
148.7
145
*
Q10.0
ICD-10 Finland
Congenital ptosis
+∞
122.9
117
*
R22.1
ICD-10 Finland
Localized swelling, mass and lump, neck
8.7
115.6
263
334
Q14.10
ICD-10 Finland
Congenital retinoschis
+∞
72.2
69
*
TCC10
NOMESCO Finland
Probing of lacrimal canaliculus/duct
28.7
63.1
86
31
Q16.1
ICD-10 Finland
Congenital absence, atresia and stricture of auditory canal (external)
+∞
62.8
60
*
Q17.2
ICD-10 Finland
Microtia
+∞
61.7
59
*
EP1AE
NOMESCO Finland
Neck ultrasound examination
4.3
56.3
221
547
DAB20
NOMESCO Finland
Closure of preauricular fistula
266.0
51.3
52
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.0
45.3
704
4044
Q14.2
ICD-10 Finland
Congenital malformation of optic disc
+∞
40.7
39
*
ZXA00
NOMESCO Finland
Right side
2.1
39.3
552
3014
Q15.0
ICD-10 Finland
Congenital glaucoma
+∞
37.6
36
*
ZXA10
NOMESCO Finland
Bilateral
2.2
36.5
437
2220
Q14.8
ICD-10 Finland
Other congenital malformations of posterior segment of eye
+∞
34.4
33
*
DAD10
NOMESCO Finland
Reconstruction of auricle
341.7
34.0
34
*
EP1DG
NOMESCO Finland
Very extensive examination of soft tissue of neck with high intesity magnet
13.5
30.5
53
40
Q16.3
ICD-10 Finland
Congenital malformation of ear ossicles
+∞
29.2
28
*
H27.0
ICD-10 Finland
Aphakia
34.1
28.7
37
11
ZXA05
NOMESCO Finland
Left side
1.9
28.5
470
2691
Z01.1
ICD-10 Finland
Examination of ears and hearing
2.1
27.2
342
1757
Q16.0
ICD-10 Finland
Congenital absence of (ear) auricle
+∞
27.1
26
*
H02.4
ICD-10 Finland
Ptosis of eyelid
5.3
26.1
81
157
Q18.2
ICD-10 Finland
Other branchial cleft malformations
+∞
25.0
24
*
Q18.9
ICD-10 Finland
Congenital malformation of face and neck, unspecified
+∞
25.0
24
*
Q17.3
ICD-10 Finland
Other misshapen ear
+∞
25.0
24
*
XCD00
NOMESCO Finland
Clinical examination of eye in general anaesthesia
68.1
23.8
27
*
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
7.0
23.0
57
83
Q13.0
ICD-10 Finland
Coloboma of iris
+∞
22.9
22
*
CCA20
NOMESCO Finland
Incision of lacrimal punctum or canaliculus
30.3
22.8
30
10
CBJ40
NOMESCO Finland
Resection of levator muscle of eyelid
14.3
22.6
38
27
Z96.1
ICD-10 Finland
Presence of intraocular lens
2.5
22.4
178
732
H90.0
ICD-10 Finland
Conductive hearing loss, bilateral
8.2
21.2
47
58
H90.1
ICD-10 Finland
Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
5.9
21.0
59
102
S01ED01
ATC
timolol; ophthalmic
4.5
20.8
74
167
UDC00
NOMESCO Finland
Ear microscopy
2.3
20.7
202
922
L02.1
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of neck
7.8
20.5
47
61
Q89.23
ICD-10 Finland
Cyst of the ductus thyreoglossus
40.4
19.5
24
6
Q17.8
ICD-10 Finland
Other specified congenital malformations of ear
+∞
18.8
18
*
Q17.0
ICD-10 Finland
Accessory auricle
+∞
18.8
18
*
CBJ10
NOMESCO Finland
Fascia plate sling or synthetic material for ptosis correction
191.3
18.6
19
*
DFF00
NOMESCO Finland
Pure tone audiometry
2.3
18.5
178
809
L04.0
ICD-10 Finland
Acute lymphadenitis of face, head and neck
5.0
18.1
58
118
Q14.18
ICD-10 Finland
Congenital malformation of retina
+∞
17.7
17
*
XCK10
NOMESCO Finland
Photography of fundus of eye
2.2
17.7
188
895
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
3.3
17.7
89
274
7433A
ICD-9 Finland
Congenital anomalies of eye, Congenital cataract and lens anomalies
95.7
17.6
19
*
74439
ICD-8 Finland
Congenital anomalies of eye, Cataracta NUD
181.2
17.5
18
*
H53.0
ICD-10 Finland
Amblyopia ex anopsia
4.6
17.3
60
133
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
8.0
17.0
38
48
Z31.5
ICD-10 Finland
Genetic counselling
2.3
16.8
156
695
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
5.8
16.3
46
81
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.7
16.1
354
2197
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
2.3
15.8
147
656
EP2AT
NOMESCO Finland
Neck soft tissue cytology with ultrasound guidance
15.8
15.7
25
16
74482
ICD-8 Finland
Congenital anomalies of eye, Ptosis
85.6
15.6
17
*
Q10.30
ICD-10 Finland
Other congenital malformations of eyelid
160.9
15.5
16
*
H04.5
ICD-10 Finland
Stenosis and insufficiency of lacrimal passages
4.3
15.5
57
135
WX110
NOMESCO Finland
Local anesthesy
1.4
15.3
1678
14715
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.9
15.0
226
1239
H33.1
ICD-10 Finland
Retinoschisis and retinal cysts
12.5
14.9
26
21
S01ED51
ATC
timolol, combinations; ophthalmic
2.6
14.8
105
408
114
Kela drug reimbursment
Glaucoma
2.5
14.3
111
452
XW1AT
NOMESCO Finland
Biopsy from other organ close to skin with ultrasound quidance
8.7
14.2
30
35
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
7.7
14.1
32
42
S01EA05
ATC
brimonidine; ophthalmic (sympathomimetics in glaucoma therapy)
5.1
14.1
44
88
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
1.5
14.0
516
3647
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.9
14.0
209
1139
ZXB10
NOMESCO Finland
Medial
7.5
13.9
32
43
WX402
NOMESCO Finland
General anaesthesia
1.6
13.8
376
2466
CHF05
NOMESCO Finland
Transscleral laser coagulation of ciliary body
13.6
13.7
23
17
Q87.88
ICD-10 Finland
Other specified congenital malformation syndromes, not elsewhere classified
14.8
13.6
22
15
Q17.9
ICD-10 Finland
Congenital malformation of ear, unspecified
+∞
13.5
13
*
Q13.1
ICD-10 Finland
Absence of iris
+∞
13.5
13
*
DBD30
NOMESCO Finland
Correction of atresia of external auditory canal
140.7
13.5
14
*
EP1CM
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with 3 Tesla magnet
16.3
13.4
21
13
DBD20
NOMESCO Finland
Plastic repair of external auditory canal
12.9
13.4
23
18
H90.6
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, bilateral
4.5
13.3
46
103
J01DA01
ATC
[U] cefalexin; systemic
1.4
13.3
1296
10991
H55
ICD-10 Finland
Nystagmus and other irregular eye movements
8.6
13.2
28
33
DAB00
NOMESCO Finland
Excision of lesion of auricle
7.9
13.1
29
37
XCK00
NOMESCO Finland
Perimetry
2.3
13.0
118
521
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.0
12.6
158
806
DEE00
NOMESCO Finland
Osseous fixation of hearing aid
130.6
12.4
13
*
XCW99
NOMESCO Finland
Other investigative procedure of eye
1.9
12.4
186
1017
CKD60
NOMESCO Finland
Anterior vitrectomy
9.7
12.2
24
25
S01EC01
ATC
acetazolamide; systemic
3.9
12.1
49
128
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.4
11.5
643
4924
H90.7
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
4.9
11.1
35
72
S01AX11
ATC
[U] ofloxacin; ophthalmic
2.8
11.0
69
250
DAX00
NOMESCO Finland
Adjustment or review of hearing aid
2.9
10.9
66
235
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
10.9
603
4602
R22.0
ICD-10 Finland
Localized swelling, mass and lump, head
3.0
10.8
62
212
TCG10
NOMESCO Finland
Removal of sutures from cornea
9.6
10.7
21
22
Q67.0
ICD-10 Finland
Facial asymmetry
60.2
10.6
12
*
C77.0
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Lymph nodes of head, face and neck
8.0
10.6
23
29
J01DB01
ATC
cefalexin; oral
1.4
10.5
1855
16958
R5130
NOMESCO Finland
Repair work or maintenance done on the aid
3.2
10.5
53
167
Q12.1
ICD-10 Finland
Congenital displaced lens
+∞
10.4
10
*
Q13.4
ICD-10 Finland
Other congenital corneal malformations
+∞
10.4
10
*
Q10.2
ICD-10 Finland
Congenital entropion
+∞
10.4
10
*
Q14.0
ICD-10 Finland
Congenital malformation of vitreous humour
+∞
10.4
10
*
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.0
10.4
137
716
QA4S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in face
6.4
10.3
26
41
UJC01
NOMESCO Finland
Scopy of lower throat
5.5
9.9
28
51
H26.4
ICD-10 Finland
After-cataract
2.2
9.9
100
468
XCD10
NOMESCO Finland
Electrophysiological examination of eye
3.3
9.9
48
147
ZZG00
NOMESCO Finland
Graft of cartilage
16.8
9.9
15
9
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.4
9.8
434
3168
8260/3-C73.9
ICD-O-3
Papillary adenocarcinoma, NOS, of thyroid gland
5.0
9.7
30
61
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.6
9.7
288
1927
WX400
NOMESCO Finland
Inhalation anesthesy
2.0
9.4
123
640
CJF10
NOMESCO Finland
Secondary implantation of artificial lens in posterior chamber
100.4
9.4
10
*
H26.00
ICD-10 Finland
Infantile, juvenile and presenile cataract
30.1
9.4
12
*
Q16.4
ICD-10 Finland
Other congenital malformations of middle ear
+∞
9.4
9
*
Q16.9
ICD-10 Finland
Congenital malformation of ear causing impairment of hearing, unspecified
+∞
9.4
9
*
7442B
ICD-9 Finland
Congenital anomalies of ear, face and neck, Other specified anomalies of ear[MICROTIA]
+∞
9.4
9
*
DAW99
NOMESCO Finland
Other operation on auricle
21.8
9.3
13
6
CJB10
NOMESCO Finland
Laser discission of secondary cataract
2.2
9.1
91
424
3793A
ICD-9 Finland
Other disorders of eye, Aphakia and other disorders of lens[APHAKIA]
36.8
9.0
11
*
C73.91
ICD-10 Finland
Papillary carcinoma of the thyroid gland (thyroid gland)
4.1
8.9
33
81
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
8.9
948
7967
H26.01
ICD-10 Finland
Infantile, juvenile and presenile cataract
24.1
8.9
12
5
DC1AD
NOMESCO Finland
Temporalbone CT
4.3
8.9
31
72
JDB10
NOMESCO Finland
Percutaneous gastrostomy
3.8
8.8
35
92
DDA00
NOMESCO Finland
Stapedotomy
6.3
8.8
22
35
S01EX03
ATC
NA
4.3
8.6
30
70
DFF15
NOMESCO Finland
Speech audiometry
2.5
8.6
64
260
WX140
NOMESCO Finland
Parabulbar anesthesy
2.5
8.5
65
264
H44.5
ICD-10 Finland
Degenerated conditions of globe
27.6
8.5
11
*
Q87.09
ICD-10 Finland
Other congenital malformations that mainly affect the appearance of the face
27.6
8.5
11
*
R3120
NOMESCO Finland
Training in mobility skills
20.1
8.5
12
6
4105
FHL
Earlobe reconstruction or plastic
90.3
8.4
9
*
74420
ICD-8 Finland
Congenital anomalies of eye, Buphthalmus (glaucoma)
90.3
8.4
9
*
7432A
ICD-9 Finland
Congenital anomalies of eye, Buphthalmos[GLAUCOMA CONGENITUM]
+∞
8.3
8
*
Q11.1
ICD-10 Finland
Other anophthalmos
+∞
8.3
8
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.3
8.3
698
5666
S01EC04
ATC
brinzolamide; ophthalmic
2.8
8.2
49
175
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.0
8.1
101
519
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
8.1
802
6654
CJD20
NOMESCO Finland
Extracapsular cataract extraction with implantation of artificial lens in posterior chamber
17.2
8.1
12
7
4CJ01
NOMESCO Finland
NA
17.2
8.1
12
7
H27.1
ICD-10 Finland
Dislocation of lens
11.7
8.1
14
12
D18.1
ICD-10 Finland
Lymphangioma, any site
8.9
8.0
16
18
8070/3-C09.9
ICD-O-3
Squamous cell carcinoma, NOS, of tonsil, NOS
22.1
8.0
11
5
Q21.00
ICD-10 Finland
Multiple ventricular septal defect
5.3
8.0
23
44
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
2.2
8.0
74
336
S01EC03
ATC
dorzolamide; ophthalmic
4.8
7.9
25
53
R5210
NOMESCO Finland
Assessment of the improvements needed in the living environment
13.1
7.9
13
10
JN5PN
NOMESCO Finland
Isotope imaging of secondary neoplasms of thyroid origin
7.8
7.9
17
22
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.7
7.8
167
1026
CK2L4
NOMESCO Finland
Wide-field/panoramic imaging of ocular fundus
4.9
7.6
23
47
3768
FHL
Eye examination under general anesthesia
25.1
7.6
10
*
H26.2
ICD-10 Finland
Complicated cataract
4.0
7.6
28
70
D11.0
ICD-10 Finland
Benign neoplasm: Parotid gland
3.2
7.5
37
117
Z97.4
ICD-10 Finland
Presence of external hearing-aid
2.5
7.5
56
228
CBJ99
NOMESCO Finland
Other operation for ptosis
80.3
7.4
8
*
C09.0
ICD-10 Finland
Malignant neoplasm: Tonsillar fossa
13.4
7.4
12
9
QAB10
NOMESCO Finland
Major dressing of wound of skin of head or neck
6.0
7.4
19
32
CBJ30
NOMESCO Finland
Plastic repair of levator aponeurosis of eyelid
8.4
7.3
15
18
Q14.9
ICD-10 Finland
Congenital malformation of posterior segment of eye, unspecified
+∞
7.3
7
*
7436B
ICD-9 Finland
Congenital anomalies of eyelids, lachrymal system and orbit[PTOSIS CONGENITA]
+∞
7.3
7
*
Q87.27
ICD-10 Finland
CHARGE association
+∞
7.3
7
*
Q11.2
ICD-10 Finland
Microphthalmos
+∞
7.3
7
*
QAA10
NOMESCO Finland
Incision of skin of head or neck
9.4
7.3
14
15
ZXC10
NOMESCO Finland
Use of laser
2.7
7.3
45
166
CHD99
NOMESCO Finland
Other filtering operation
15.8
7.2
11
7
UGC02
NOMESCO Finland
Rigid bronchoscopy
5.4
7.2
20
37
P85
ICPC
Mental retardation
5.4
7.2
20
37
H33.0
ICD-10 Finland
Retinal detachment with retinal break
2.9
7.2
42
148
N02BE01
ATC
paracetamol; systemic, rectal
1.3
7.2
1759
16252
H60.9
ICD-10 Finland
Otitis externa, unspecified
1.7
7.2
143
862
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
3.5
7.2
31
89
R51.80
ICD-10 Finland
Headache
1.4
7.1
340
2507
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.4
7.1
460
3573
Z01.8
ICD-10 Finland
Other specified special examinations
1.4
7.1
406
3091
R59.1
ICD-10 Finland
Generalized enlarged lymph nodes
3.2
7.0
34
107
S01EE01
ATC
latanoprost; ophthalmic
2.2
6.9
67
312
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
2.8
6.9
41
147
D21.0
ICD-10 Finland
Benign neoplasm: Connective and other soft tissue of head, face and neck
5.8
6.9
18
31
WX002
NOMESCO Finland
Sedation and analgesia
1.4
6.9
310
2264
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
1.9
6.8
93
497
S01EE05
ATC
tafluprost; ophthalmic
2.8
6.8
40
143
ENA32
NOMESCO Finland
Incision of deep pharyngeal infection
9.3
6.8
13
14
KFH00
NOMESCO Finland
Operation for undescended or ectopic testis
5.3
6.8
19
36
H18.1
ICD-10 Finland
Bullous keratopathy
40.2
6.8
8
*
ENB99
NOMESCO Finland
Other excision of pharynx and adjacent structures
16.7
6.7
10
6
H52.2
ICD-10 Finland
Astigmatism
2.5
6.7
49
199
R13
ICD-10 Finland
Dysphagia
1.9
6.7
96
523
H57.0
ICD-10 Finland
Anomalies of pupillary function
4.7
6.7
21
45
EP1AT
NOMESCO Finland
Punction of soft tissue of neck with ultrasound guidance
22.6
6.7
9
*
H52.1
ICD-10 Finland
Myopia
1.9
6.7
89
470
ZX114
NOMESCO Finland
Intramuscular
3.0
6.6
36
123
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
1.7
6.6
122
719
Q21.21
ICD-10 Finland
Atrioventricular duct
70.0
6.4
7
*
Q87.03
ICD-10 Finland
Syndrome Goldenhar
70.0
6.4
7
*
3242
FHL
Levator resection
70.0
6.4
7
*
BAA60
NOMESCO Finland
Total thyroidectomy
2.6
6.4
45
177
WX704
NOMESCO Finland
Intubation
1.7
6.4
132
804
SPAT1153
SPAT
Removal of sutures
1.3
6.4
513
4111
Q21.08
ICD-10 Finland
Other specifed ventricular septal defect
3.4
6.3
28
83
S01EA03
ATC
apraclonidine; ophthalmic
5.2
6.3
18
35
H03AA01
ATC
levothyroxine sodium; systemic
1.4
6.3
373
2852
Q10.1
ICD-10 Finland
Congenital ectropion
+∞
6.3
6
*
Q16.2
ICD-10 Finland
Absence of eustachian tube
+∞
6.3
6
*
3621
FHL
In the aftermath of the dissection
+∞
6.3
6
*
Q87.8
ICD-10 Finland
Other specified congenital malformation syndromes, not elsewhere classified
+∞
6.3
6
*
BA1NN
NOMESCO Finland
I-131 dose capsel measurement
26.7
6.2
8
*
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
1.6
6.1
142
897
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.2
6.0
1175
10471
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.7
6.0
105
611
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
139
419
3.44
38.17
1.3
1.2
—
—
—
0
0
2419
22544
1.62
14.58
13.2
11.5
22.0
21.7
mg/l
0.18
1911
17199
1111
9237
1.34
12.09
8.4
7.1
1.2
1.2
mmol/l
0.42
947
7894
1022
8416
1.34
11.77
8.0
6.7
1.2
1.2
mmol/l
0.38
941
7717
2314
21565
1.47
11.70
14.4
12.4
139.6
139.6
mmol/l
0.02
2261
20941
2317
21619
1.46
11.44
14.6
12.5
3.9
3.9
mmol/l
0.30
2260
20944
1357
11715
1.31
10.95
5.7
4.9
6.4
6.4
mmol/l
0.26
1251
10722
1463
12823
1.30
10.28
8.6
9.1
4.1
3.9
e9/l
1.67
1300
11170
948
7842
1.32
10.20
5.4
5.1
36.6
36.6
g/l
0.17
877
7319
55
218
2.55
9.46
6.9
4.3
139.2
93.2
u/ml
0.25
20
66
1916
17515
1.31
9.33
4.3
3.9
14.7
14.5
pmol/l
1.62
1746
16108
1690
15196
1.29
9.32
7.1
6.8
79.1
79.7
u/l
0.16
1598
14325
2172
20331
1.33
8.13
5.1
4.5
1.9
2.0
mu/l
0.37
2028
19048
2425
23115
1.43
7.94
14.0
12.4
72.8
71.3
umol/l
1.27
2425
23106
1252
10993
1.26
7.76
6.4
6.3
55.6
55.4
%
0.23
1181
10391
1712
15589
1.26
7.70
4.0
3.9
9.6
9.9
mm/h
0.32
1599
14512
1574
14210
1.25
7.55
4.5
4.0
1289.5
1382.4
e6/l
0.03
22
171
2636
25615
1.76
7.51
19.4
16.8
261.2
258.9
e9/l
1.14
2586
24954
28
88
3.20
7.39
1.3
1.1
88.6
93.3
%
0.43
15
44
1265
11162
1.25
7.37
6.6
6.5
30.1
30.2
%
0.23
1195
10521
2638
25656
1.75
7.26
19.6
16.9
136.0
135.8
g/l
0.21
2617
25333
2637
25645
1.75
7.24
19.3
16.8
4.6
4.6
e12/l
0.09
2584
24934
2637
25654
1.74
7.10
19.4
16.9
6.9
6.8
e9/l
1.21
2584
24938
1123
9820
1.24
6.97
5.7
5.9
12.6
12.0
umol/l
0.37
1052
9234
2068
19432
1.26
6.23
11.2
9.8
91.8
92.0
ml/min/173m2
0.15
1662
15518
623
5155
1.27
6.12
2.2
2.2
206.6
225.6
u/l
0.17
591
4891
2098
19775
1.26
5.99
15.6
14.1
13.3
13.4
%
1.60
2052
19376
25
84
2.99
5.95
1.4
1.3
86.3
89.7
%
0.18
13
42
987
8631
1.22
5.83
2.6
2.4
75.0
72.9
nmol/l
1.47
910
7988
209
1481
1.44
5.75
3.8
3.3
4.7
4.7
pmol/l
0.00
185
1314
1134
10075
1.21
5.67
4.2
4.0
—
—
—
0
0
168
1147
1.49
5.59
7.3
6.8
24.5
24.4
mmol/l
0.22
160
1112
711
6042
1.24
5.45
2.7
2.6
57.6
56.1
u/l
0.22
664
5598
473
3838
1.28
5.39
3.6
3.3
1392.8
1097.3
ng/l
0.38
391
3175
728
6227
1.23
5.22
3.4
3.1
43.2
46.9
ng/l
0.10
406
3474
15
40
3.76
5.09
1.1
1.5
—
—
—
0
0
210
1526
1.41
5.05
6.8
6.3
1.3
1.3
mmol/l
0.06
160
1100
2417
23299
1.32
5.04
9.5
9.0
26.5
26.3
u/l
0.15
2344
22549
215
1571
1.40
5.01
6.8
6.2
5.2
5.1
kpa
1.60
204
1486
74
432
1.73
4.74
1.3
1.4
—
—
—
0
0
182
1322
1.40
4.42
5.5
4.8
88.1
76.7
ng/l
0.89
163
1204
258
1991
1.33
4.28
6.2
5.9
5.9
5.8
kpa
0.24
251
1937
356
2869
1.28
4.27
2.0
1.8
—
—
—
0
0
257
1983
1.33
4.26
6.2
5.9
1.4
1.6
mmol/l
0.52
209
1567
2028
19264
1.20
4.26
3.4
3.3
1.3
1.2
mmol/l
0.58
1893
18058
236
1803
1.34
4.19
1.4
1.3
340.4
238.6
u/ml
0.33
214
1672
2050
19512
1.20
4.12
4.0
3.6
5.7
5.7
mmol/l
0.37
1886
18063
585
5005
1.21
4.07
2.4
2.3
—
—
—
0
0
210
1593
1.34
3.93
12.0
10.6
24.9
24.6
mmol/l
0.84
210
1587
440
3676
1.23
3.85
1.3
1.3
28.7
27.1
iu/ml
0.09
121
1084
338
2751
1.26
3.74
3.1
2.4
2.4
2.4
g/l
0.39
315
2548
707
6215
1.19
3.62
3.3
3.1
2.4
2.4
mmol/l
0.16
616
5562
795
7068
1.18
3.55
3.0
3.4
29.6
31.5
u/l
1.01
752
6740
176
1326
1.35
3.47
5.7
6.8
23.7
23.9
mmol/l
0.28
164
1240
154
1137
1.38
3.45
3.2
3.6
159.6
172.7
ng/l
0.18
136
1013
1209
11120
1.16
3.44
3.2
2.9
86.2
88.9
ug/l
0.23
1133
10456
223
1741
1.31
3.44
5.2
5.7
5.0
4.8
kpa
0.68
217
1690
796
7095
1.17
3.43
1.9
1.8
95.4
96.7
pmol/l
0.39
430
3866
210
1631
1.31
3.37
2.1
2.1
11.4
11.8
nmol/l
0.25
185
1434
395
3309
1.23
3.37
2.7
2.7
1.0
1.2
e6/l
0.45
235
1816
363
3019
1.23
3.32
3.2
2.4
13.3
14.1
umol/l
1.29
342
2807
2106
20214
1.18
3.30
3.8
3.7
4.6
4.7
mmol/l
0.64
1985
19060
414
3493
1.22
3.29
2.6
2.7
137.9
114.6
ug/g
0.50
348
2753
654
5756
1.18
3.27
3.5
3.5
8.0
8.2
mmol/l
0.46
556
5007
321
2643
1.24
3.22
9.8
7.1
1.1
1.1
mmol/l
0.61
306
2478
376
3150
1.22
3.21
2.8
2.8
3.7
3.0
e6/l
0.55
216
1659
2092
20084
1.18
3.20
3.8
3.6
1.4
1.5
mmol/l
1.66
1960
18852
309
2537
1.25
3.18
3.3
2.5
22.3
23.6
%
0.84
269
2217
171
1305
1.33
3.12
1.7
1.7
—
—
—
0
0
2121
20405
1.17
3.08
4.1
3.9
2.8
2.8
mmol/l
0.20
1985
19095
2276
22055
1.19
2.89
13.7
12.4
40.3
40.1
%
0.52
1814
17755
108
781
1.40
2.80
9.6
10.6
1.4
1.3
mg/l
0.86
101
747
1859
17759
1.15
2.78
4.9
4.6
38.2
38.2
mmol/mol
0.12
1728
16701
85
590
1.45
2.76
2.4
2.6
322.7
404.0
ug/l
0.25
79
544
18
78
2.32
2.74
1.2
1.3
—
—
—
0
0
711
6383
1.15
2.70
1.4
1.4
1.5
1.8
u/ml
0.35
187
1631
281
2328
1.23
2.69
2.8
3.5
7.9
7.3
umol/l
0.12
240
1976
523
4596
1.17
2.63
4.6
4.1
11.7
14.0
mg/mmol
0.20
351
3030
38
221
1.73
2.61
2.0
2.9
12.5
10.9
%
0.35
25
150
18
80
2.26
2.60
1.2
1.3
—
—
—
0
0
403
3470
1.19
2.59
1.3
1.2
11.0
10.5
u/ml
0.05
158
1383
249
2046
1.24
2.58
2.2
2.3
7295.9
7074.5
u/l
0.04
106
789
63
419
1.52
2.54
7.9
4.1
5.1
4.9
kpa
0.61
63
414
30
164
1.84
2.53
1.1
1.1
—
—
—
0
0
185
1473
1.27
2.52
1.5
1.5
18.5
19.7
iu/l
0.24
146
1187
73
502
1.47
2.51
6.5
7.0
668.7
306.3
iu/ml
0.37
13
63
640
5733
1.15
2.49
4.1
3.5
0.0
0.0
estimate
1.49
229
2114
528
4663
1.16
2.49
2.0
2.2
1.1
1.0
mg/l
0.27
382
3413
12
45
2.67
2.45
3.5
2.8
—
—
—
0
0
12
45
2.67
2.45
3.5
2.8
—
—
—
0
0
13
51
2.56
2.44
3.6
6.7
—
—
—
0
0
253
2097
1.23
2.43
6.3
7.4
104.6
104.7
mmol/l
0.09
244
2059
145
1125
1.30
2.42
1.7
1.6
9.1
8.4
u/l
0.22
114
879
48
304
1.59
2.41
1.6
1.2
—
—
—
0
0
121
916
1.34
2.40
8.9
7.7
9.2
9.2
kpa
0.11
116
870
111
831
1.35
2.38
15.2
12.0
—
—
—
0
0
1596
15176
1.12
2.35
3.1
3.1
38.9
39.2
u/l
0.05
1511
14423
473
4162
1.16
2.34
3.1
2.6
10.9
7.2
e6/l
0.45
406
3671
337
2887
1.19
2.31
2.9
3.2
29.5
29.9
s
0.54
331
2801
1148
10719
1.12
2.31
3.7
3.3
0.0
0.0
estimate
1.08
224
2108
99
732
1.37
2.30
1.9
1.8
—
—
—
0
0
212
1737
1.24
2.28
11.7
9.4
7.6
7.6
mmol/l
0.06
206
1677
418
3651
1.17
2.27
1.6
1.6
51923533.3
34731543.2
pmol/l
0.18
364
3124
619
5567
1.14
2.27
3.4
3.1
0.6
0.3
e6/l
0.93
468
4141
72
507
1.43
2.23
1.7
1.8
—
—
—
0
0
122
937
1.32
2.22
7.2
7.8
25.2
24.3
mmol/l
1.82
110
874
45
288
1.57
2.19
1.8
1.5
—
—
—
0
0
1146
10722
1.12
2.19
5.2
4.5
0.0
0.0
estimate
0.50
235
2173
234
1951
1.22
2.15
2.0
1.7
—
—
—
0
0
26
144
1.81
2.14
1.0
1.2
—
—
u/ml
—
0
0
35
212
1.66
2.13
2.1
3.0
—
—
—
0
0
213
1763
1.23
2.10
10.1
8.5
1.2
0.9
mmol/l
0.55
160
1353
237
1983
1.21
2.10
2.0
1.8
—
—
—
0
0
40
252
1.60
2.09
1.3
1.4
—
—
—
0
0
341
2957
1.17
2.04
5.4
5.0
0.8
0.8
mmol/l
0.28
321
2791
369
3223
1.17
2.02
3.8
3.3
1024.3
462.7
ng/l
0.51
227
2088
258
2186
1.20
2.02
2.5
2.2
360.6
372.3
nmol/l
0.40
238
2029
216
1801
1.22
2.00
2.9
2.9
10.3
10.2
g/l
0.09
202
1667
1151
10812
1.11
2.00
3.8
3.3
0.0
0.0
estimate
0.80
228
2105
130
1024
1.28
1.99
5.6
4.5
130.4
130.7
g/l
0.05
125
1001
39
249
1.57
1.95
1.3
1.4
—
—
—
0
0
105
807
1.31
1.94
5.2
4.4
1.3
1.3
%
0.14
105
802
447
3974
1.15
1.93
1.6
1.5
20.8
20.2
nmol/l
0.36
386
3474
448
3985
1.15
1.92
4.5
4.3
2.2
2.1
ug/l
0.06
398
3601
65
464
1.41
1.91
2.4
2.7
—
—
—
0
0
26
150
1.74
1.90
3.5
2.4
—
—
—
0
0
83
618
1.35
1.90
1.8
1.9
3.8
4.7
iu/l
0.67
28
229
579
5245
1.13
1.89
2.3
2.3
2.8
2.8
mg/l
0.11
504
4537
237
2009
1.20
1.86
4.3
3.7
1.8
1.7
%
0.41
214
1820
209
1751
1.21
1.86
15.2
18.8
1.2
1.2
inr
0.04
45
277
138
1107
1.26
1.84
1.6
1.5
—
—
—
0
0
210
1764
1.21
1.82
1.1
1.1
—
—
—
0
0
5
12
4.17
1.82
1.0
1.0
—
—
—
0
0
234
1986
1.19
1.82
1.2
1.2
142.9
155.0
iu/ml
0.19
99
741
14
66
2.13
1.81
1.3
1.3
—
—
—
0
0
14
66
2.13
1.81
1.3
1.3
—
—
—
0
0
171
1408
1.23
1.81
5.1
3.5
1.2
1.2
mmol/l
0.82
153
1216
504
4538
1.14
1.81
2.8
2.7
2226.8
4465.0
umol/l
0.90
452
4028
175
1448
1.22
1.77
10.0
9.2
123.4
123.2
g/l
0.03
165
1397
52
362
1.44
1.77
1.7
1.9
—
—
—
0
0
38
248
1.54
1.76
1.3
1.4
—
—
—
0
0
66
481
1.38
1.75
1.2
1.3
—
—
—
0
0
50
347
1.45
1.73
1.8
1.6
—
—
—
0
0
110
867
1.28
1.71
4.1
5.6
93.5
92.1
%
0.31
103
814
86
656
1.32
1.71
2.0
1.7
—
—
—
0
0
45
308
1.47
1.68
1.4
1.5
—
—
—
0
0
58
417
1.40
1.67
1.2
1.1
31.3
1183.0
iu/ml
0.59
19
122
326
2871
1.15
1.63
1.8
1.7
1082.5
1183.3
nmol/l
1.26
250
2224
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
64
471
1.37
1.62
8.0
8.1
0.3
0.4
u/ml
0.64
36
261
242
2084
1.18
1.62
4.2
3.7
31.9
32.1
%
0.09
175
1509
46
320
1.44
1.60
1.7
1.8
—
—
—
0
0
36
239
1.51
1.57
5.4
7.8
10.7
10.6
mg/l
0.04
31
222
886
8295
1.10
1.57
4.0
3.3
—
—
—
0
0
208
1777
1.18
1.54
10.2
8.4
5.2
5.1
kpa
0.50
197
1702
208
1777
1.18
1.54
10.2
8.4
12.7
12.9
kpa
0.24
198
1704
110
881
1.26
1.53
1.3
1.2
0.2
1.0
u/ml
—
9
74
37
249
1.49
1.52
1.3
1.4
—
—
—
0
0
24
146
1.65
1.50
1.0
1.6
—
—
—
0
0
37
250
1.49
1.50
1.3
1.4
—
—
—
0
0
191
1625
1.19
1.49
10.4
8.0
1.5
1.4
mmol/l
0.53
185
1541
33
218
1.52
1.48
1.2
1.7
—
—
—
0
0
13
65
2.00
1.48
5.8
8.8
—
—
—
0
0
37
251
1.48
1.47
1.3
1.4
—
—
—
0
0
26
163
1.60
1.46
1.3
1.3
63.5
258.8
pmol/l
—
9
48
41
285
1.45
1.45
2.2
3.3
0.9
1.4
%
0.68
35
236
7
28
2.50
1.45
4.4
9.4
—
—
—
0
0
352
3147
1.14
1.43
3.8
3.8
21.1
21.0
%
0.03
159
1342
67
508
1.33
1.43
1.8
1.8
—
—
—
0
0
33
221
1.50
1.41
2.1
3.1
0.2
0.2
e9/l
0.28
23
184
31
205
1.52
1.40
1.5
1.4
1.3
1.2
promille
0.12
23
161
123
1010
1.23
1.40
12.3
10.2
94.1
94.0
%
0.07
123
1004
33
224
1.48
1.33
2.1
3.0
373.9
544.9
e6/l
1.85
23
184
89
709
1.26
1.33
5.5
4.0
51.9
50.7
%
0.17
89
701
39
274
1.43
1.33
1.4
1.5
9.8
12.0
mmol/l
—
6
45
76
594
1.29
1.32
7.2
6.6
1.6
1.6
%
0.14
68
553
735
6871
1.10
1.32
1.7
1.7
—
—
—
0
0
32
217
1.48
1.30
1.2
1.8
—
—
—
0
0
174
1490
1.18
1.29
1.6
1.6
371.1
307.5
mu/l
1.24
159
1327
16
91
1.76
1.29
2.6
1.8
—
—
—
0
0
5
18
2.78
1.28
1.0
1.2
—
—
—
0
0
35
244
1.44
1.25
1.9
1.5
—
—
—
0
0
19
115
1.66
1.24
2.4
4.2
207.4
158.6
umol/l
0.21
12
65
1932
18829
1.09
1.24
3.8
3.7
—
—
—
0
0
41
295
1.40
1.24
1.2
1.3
—
—
—
0
0
8
36
2.23
1.24
1.0
1.3
—
—
—
0
0
11
56
1.97
1.22
1.3
1.4
—
—
—
0
0
165
1415
1.18
1.21
2.6
2.5
74.4
74.1
ml/min/173m2
0.04
63
529
74
585
1.27
1.20
1.9
2.0
1.1
1.8
ug/l
0.39
64
518
23
148
1.56
1.20
1.5
1.6
23.8
33.9
%
0.82
14
95
36
255
1.42
1.19
1.3
1.6
—
—
—
0
0
114
947
1.21
1.19
1.8
1.7
—
—
—
0
0
8
38
2.11
1.18
1.3
1.4
—
—
—
0
0
30
206
1.46
1.17
1.7
1.7
57.6
56.2
%
0.06
19
138
5
20
2.50
1.15
1.2
1.1
—
—
—
0
0
5
20
2.50
1.15
1.8
1.3
38.1
14.6
nmol/l
—
5
20
69
545
1.27
1.14
1.7
1.6
—
—
—
0
0
208
1829
1.15
1.12
2.9
2.9
—
—
—
0
0
55
423
1.31
1.12
2.3
2.4
128.2
132.5
g/l
0.69
43
327
220
1944
1.14
1.11
5.0
4.6
243.2
245.5
u/l
0.07
212
1851
513
4765
1.09
1.07
4.1
3.4
1.0
1.0
kg/l
0.07
71
696
216
1913
1.14
1.06
2.1
2.4
33.2
63.1
u/l
0.62
197
1614
59
462
1.28
1.06
3.3
4.1
3.7
3.9
mmol/l
1.52
51
435
142
1220
1.17
1.05
2.1
2.3
7.4
7.3
ug/l
0.02
115
1090
35
254
1.38
1.04
1.8
1.6
—
—
—
0
0
5
22
2.27
1.03
1.0
1.1
—
—
—
0
0
11
60
1.84
1.02
1.1
1.7
—
—
—
0
0
17
106
1.61
1.02
2.5
1.7
—
—
—
0
0
98
817
1.21
1.02
1.3
1.3
—
—
—
0
0
229
2043
1.13
1.02
5.0
5.8
—
—
—
0
0
48
369
1.31
1.00
1.4
1.5
7.4
6.9
mmol/l
0.52
33
254
13
212
0.61
0.98
1.0
1.1
—
—
—
0
0
17
108
1.58
0.96
1.4
1.2
—
—
—
0
0
205
1825
1.13
0.95
2.3
2.8
0.2
0.2
g/l
0.69
200
1719
0
32
0.00
0.95
0.0
1.1
—
—
—
0
0
62
497
1.25
0.95
1.1
1.1
—
—
—
0
0
161
1411
1.15
0.95
1.2
1.3
38.5
42.8
au/ml
—
7
57
19
125
1.52
0.93
2.7
2.3
2.1
2.5
u/field
0.19
11
65
6
27
2.22
0.93
3.2
2.4
—
—
—
0
0
9
52
1.73
0.92
2.4
2.5
—
—
—
0
0
9
52
1.73
0.92
1.6
1.6
—
—
—
0
0
35
261
1.35
0.91
2.0
2.0
—
—
—
0
0
23
160
1.44
0.88
1.0
1.2
1.1
1.1
ratio
—
9
68
8
42
1.91
0.88
1.0
1.1
—
—
—
0
0
18
119
1.52
0.88
2.2
2.0
113.4
98.2
umol/l
—
5
24
255
2314
1.11
0.88
2.8
2.8
0.7
0.7
ug/l
0.02
150
1386
391
3625
1.09
0.87
2.2
2.1
—
—
—
0
0
574
5409
1.08
0.86
2.4
2.3
—
—
—
0
0
22
153
1.44
0.85
1.2
1.5
—
—
—
0
0
22
153
1.44
0.85
1.2
1.5
—
—
—
0
0
22
153
1.44
0.85
1.2
1.5
—
—
—
0
0
104
892
1.17
0.83
1.1
1.2
0.9
2.5
u/ml
2.02
54
438
112
968
1.16
0.82
1.6
1.6
—
—
—
0
0
37
284
1.31
0.81
1.9
2.1
1.7
1.7
mmol/l
0.03
37
279
324
2990
1.09
0.81
2.8
2.7
2.4
2.4
mmol/l
0.00
275
2617
47
373
1.26
0.81
2.9
2.6
16.3
17.0
%
0.54
27
197
10
58
1.73
0.79
1.3
1.1
—
—
—
0
0
31
234
1.33
0.77
1.5
1.5
309.7
397.6
pmol/l
0.60
26
180
84
716
1.18
0.75
1.6
1.8
0.2
0.2
g/l
0.12
77
677
5
24
2.08
0.74
1.0
1.2
—
—
—
0
0
19
133
1.43
0.73
1.2
1.3
3496.3
2302.6
e6/l
0.43
11
92
26
193
1.35
0.73
1.3
1.3
—
—
—
0
0
17
117
1.46
0.71
1.2
1.4
22596.3
86069.6
e6/l
—
8
69
5
26
1.92
0.70
1.0
1.2
—
—
—
0
0
17
118
1.44
0.69
2.1
3.0
1137.3
1197.9
u/ml
0.05
17
118
622
5927
1.06
0.69
2.5
2.4
—
—
—
0
0
66
780
0.84
0.69
1.9
1.4
—
—
—
0
0
5
27
1.85
0.68
1.0
1.2
—
—
—
0
0
64
756
0.84
0.67
1.9
1.5
203.9
218.7
u/ml
0.23
43
439
7
43
1.63
0.66
1.0
1.1
—
—
—
0
0
54
448
1.21
0.66
1.3
1.4
17.9
18.3
u/l
0.04
46
386
5
28
1.79
0.66
1.0
1.1
—
—
—
0
0
58
485
1.20
0.66
4.5
4.6
23.6
24.4
mmol/l
0.86
50
433
55
657
0.83
0.65
1.4
1.3
—
—
—
0
0
5
29
1.73
0.64
1.0
1.0
—
—
—
0
0
19
139
1.37
0.60
1.6
1.8
—
—
—
0
0
11
163
0.67
0.60
1.3
1.5
0.9
1.0
g/l
0.18
11
163
8
52
1.54
0.59
1.0
1.5
—
—
—
0
0
168
1531
1.10
0.59
2.2
2.3
17.9
20.6
au/ml
—
5
107
10
64
1.56
0.58
1.0
1.2
—
—
—
0
0
0
23
0.00
0.58
0.0
1.1
—
44.7
—
0
8
19
140
1.36
0.58
2.8
4.4
—
—
—
0
0
108
961
1.13
0.58
1.4
1.3
—
—
—
0
0
6
35
1.72
0.57
4.2
6.6
—
—
—
0
0
6
35
1.72
0.57
4.5
7.0
—
—
—
0
0
88
773
1.14
0.57
1.1
1.1
2.9
3.4
u/ml
0.13
23
228
6
36
1.67
0.56
1.5
1.8
—
—
—
0
0
6
36
1.67
0.56
1.0
1.0
44.8
14.5
u/ml
—
6
28
84
737
1.14
0.56
1.6
1.8
1.1
1.2
g/l
0.52
78
697
60
514
1.17
0.55
1.9
2.1
10.4
10.6
mg/l
0.10
53
483
40
330
1.22
0.54
1.1
1.1
—
—
—
0
0
521
4978
1.06
0.54
1.6
1.6
1.4
1.4
mmol/l
0.40
455
4315
157
1435
1.10
0.53
2.0
1.9
—
—
—
0
0
47
396
1.19
0.52
1.7
1.7
7.6
7.3
mmol/l
0.36
29
243
361
3417
1.06
0.52
1.7
1.8
1.4
1.4
%
0.26
320
3053
15
109
1.38
0.50
1.3
1.9
0.7
1.3
nmol/l
—
9
87
28
224
1.25
0.50
3.5
1.8
—
—
—
0
0
6
41
1.46
0.50
2.5
3.2
—
—
—
0
0
12
84
1.43
0.49
1.1
1.7
—
—
—
0
0
12
84
1.43
0.49
1.1
1.7
—
—
—
0
0
12
84
1.43
0.49
1.1
1.7
—
—
—
0
0
12
84
1.43
0.49
1.1
1.7
—
—
—
0
0
18
136
1.33
0.49
2.6
1.7
—
—
—
0
0
13
93
1.40
0.48
2.9
1.8
—
—
—
0
0
123
1349
0.91
0.47
1.4
1.4
—
—
—
0
0
310
2932
1.06
0.47
2.1
2.0
—
—
—
0
0
28
227
1.24
0.46
1.0
1.1
—
—
—
0
0
5
84
0.59
0.45
2.2
1.3
—
64.4
—
0
9
124
1355
0.91
0.45
1.4
1.4
—
—
—
0
0
72
638
1.13
0.45
2.1
2.8
4.4
6.2
umol/l
1.55
52
490
124
1354
0.91
0.44
1.4
1.4
—
—
—
0
0
12
86
1.40
0.44
1.3
1.4
10.7
13.9
u/l
1.16
12
81
7
51
1.37
0.44
1.0
1.1
—
—
—
0
0
124
1352
0.91
0.43
1.4
1.4
—
—
—
0
0
258
2434
1.07
0.43
1.5
1.5
—
—
—
0
0
14
104
1.35
0.43
1.1
1.2
—
—
—
0
0
19
149
1.28
0.41
1.0
1.1
1548.7
1474.7
miu/ml
0.11
19
149
17
217
0.78
0.41
1.4
1.6
—
—
titre
—
0
0
0
16
0.00
0.41
0.0
6.5
—
—
—
0
0
78
700
1.12
0.41
1.1
1.2
—
—
—
0
0
5
34
1.47
0.40
2.8
7.4
91.8
28.6
ug/min
—
5
25
37
432
0.85
0.39
1.6
1.9
—
—
—
0
0
62
550
1.13
0.39
1.4
1.5
0.3
0.4
nmol/l
0.27
51
458
146
1357
1.08
0.38
2.8
4.1
11.1
19.8
ug/l
0.49
111
1069
11
80
1.38
0.38
1.6
1.5
—
—
—
0
0
61
542
1.13
0.38
1.4
1.4
255.3
311.4
ug/g
0.90
27
291
5
36
1.39
0.38
1.0
1.1
—
—
—
0
0
9
68
1.32
0.37
1.0
1.9
—
—
—
0
0
9
68
1.32
0.37
1.0
1.9
—
—
—
0
0
13
98
1.33
0.37
1.5
1.2
0.3
0.3
g/l
—
7
82
49
430
1.14
0.37
1.3
1.3
—
—
—
0
0
49
430
1.14
0.37
1.3
1.3
—
—
—
0
0
9
70
1.29
0.36
1.0
1.9
—
—
—
0
0
30
253
1.19
0.36
1.6
1.6
—
—
—
0
0
5
76
0.66
0.35
1.0
1.1
—
—
—
0
0
88
803
1.10
0.35
1.2
1.2
—
—
—
0
0
21
171
1.23
0.35
1.5
1.7
24.7
23.8
umol/l
0.05
21
161
18
144
1.25
0.35
1.1
1.1
—
34.4
—
0
8
22
181
1.22
0.34
1.9
2.2
—
—
—
0
0
18
145
1.24
0.33
1.4
1.4
71.7
74.0
%
0.39
18
139
39
340
1.15
0.33
1.2
1.2
—
—
—
0
0
131
1222
1.08
0.33
1.9
1.8
—
—
—
0
0
22
182
1.21
0.33
1.3
1.2
—
—
—
0
0
22
183
1.20
0.31
1.3
1.2
—
—
—
0
0
7
54
1.30
0.30
1.3
2.4
1.8
3.2
nmol/l
—
7
49
10
75
1.33
0.30
1.8
2.4
—
—
—
0
0
12
93
1.29
0.30
1.2
1.1
—
—
—
0
0
45
401
1.12
0.29
1.1
1.3
2.1
4.6
u/ml
1.58
15
132
72
661
1.09
0.28
1.1
1.2
—
—
—
0
0
79
853
0.92
0.26
2.1
2.0
37.7
39.4
u/l
0.31
71
786
67
728
0.92
0.26
2.6
2.0
1.4
1.4
g/l
0.06
53
639
17
141
1.21
0.26
1.4
1.4
735.3
384.8
mu/l
1.11
17
135
50
453
1.11
0.26
1.2
1.1
—
—
—
0
0
9
72
1.25
0.25
1.0
1.1
—
—
—
0
0
25
216
1.16
0.25
2.4
2.8
716.7
842.4
e6/l
—
7
69
9
74
1.22
0.25
1.0
1.1
—
—
—
0
0
9
74
1.22
0.25
1.0
1.1
—
—
—
0
0
74
685
1.08
0.25
1.8
2.1
—
—
—
0
0
132
1251
1.06
0.24
1.3
1.3
205.6
227.7
miu/ml
0.29
57
621
68
629
1.08
0.23
1.6
1.6
—
—
—
0
0
84
784
1.07
0.23
1.7
1.6
0.2
0.1
iu/ml
0.18
13
153
5
39
1.28
0.23
1.0
1.3
—
—
—
0
0
31
276
1.12
0.22
1.0
1.1
—
—
—
0
0
262
2709
0.96
0.22
1.5
1.5
—
—
—
0
0
20
231
0.86
0.22
1.1
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
129
1227
1.05
0.21
3.0
2.7
67.4
67.0
g/l
0.24
116
1140
0
12
0.00
0.21
0.0
2.4
—
—
—
0
0
11
133
0.83
0.19
1.0
1.1
—
—
—
0
0
17
146
1.17
0.19
1.1
1.2
—
67.5
—
0
15
10
122
0.82
0.19
1.1
1.1
—
—
—
0
0
6
52
1.15
0.19
1.2
1.0
—
—
—
0
0
16
137
1.17
0.18
1.1
1.1
—
24.9
—
0
8
10
81
1.24
0.18
1.0
1.1
—
—
—
0
0
13
109
1.19
0.18
1.1
1.8
5.4
3.9
nmol/l
0.13
13
83
75
706
1.06
0.18
1.1
1.2
—
—
—
0
0
42
386
1.09
0.18
2.3
2.7
82.8
117.7
ug/min
0.23
24
253
22
195
1.13
0.17
2.0
2.0
23.2
23.6
mg/l
—
10
58
46
426
1.08
0.17
1.5
1.4
—
—
—
0
0
8
71
1.13
0.16
1.0
1.1
—
—
—
0
0
8
71
1.13
0.16
1.0
1.1
—
—
—
0
0
28
254
1.10
0.16
1.2
1.2
—
—
—
0
0
65
613
1.06
0.16
1.8
1.8
—
—
—
0
0
45
483
0.93
0.15
1.3
1.2
9.3
38.1
u/ml
—
9
43
10
119
0.84
0.15
2.2
2.8
—
—
—
0
0
10
119
0.84
0.15
2.2
2.8
—
—
—
0
0
9
81
1.11
0.15
1.3
1.2
—
—
—
0
0
170
1753
0.97
0.14
1.4
1.4
—
—
—
0
0
15
170
0.88
0.13
1.9
1.6
—
—
—
0
0
29
315
0.92
0.13
3.5
3.1
6.8
21.1
u/ml
0.52
29
281
51
481
1.06
0.13
3.7
2.2
10.2
10.3
g/l
0.03
37
418
22
242
0.91
0.13
1.2
1.2
22.5
39.1
mg/l
4.59
15
195
87
907
0.96
0.13
1.5
1.5
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
16
142
1.13
0.12
1.0
1.1
—
—
—
0
0
31
287
1.08
0.12
1.0
1.0
—
—
—
0
0
67
639
1.05
0.12
1.3
2.1
387.4
464.0
mg/l
2.16
62
606
18
162
1.11
0.11
1.0
1.1
0.9
1.0
u/l
—
7
76
11
95
1.16
0.11
1.3
1.2
—
—
—
0
0
28
302
0.93
0.11
1.0
1.1
1.5
1.5
g/l
0.13
28
269
41
386
1.06
0.11
1.7
1.7
18959.3
11858.7
e6/l
0.34
26
287
14
124
1.13
0.11
2.6
1.7
3.1
3.5
mg/l
0.36
14
119
105
1085
0.97
0.11
1.4
1.7
3.3
4.4
mg/l
0.72
70
727
31
332
0.93
0.11
1.4
1.5
—
—
—
0
0
113
1095
1.03
0.10
1.5
1.5
—
—
—
0
0
16
144
1.11
0.10
1.3
1.0
19.9
19.3
mmol/l
0.28
16
136
48
456
1.05
0.10
3.0
2.3
0.7
0.9
g/l
0.13
36
410
38
399
0.95
0.08
1.2
1.3
2.9
4.7
u/ml
1.04
14
170
145
1480
0.98
0.07
1.4
1.5
—
—
—
0
0
39
372
1.05
0.07
1.7
1.5
—
—
—
0
0
8
76
1.05
0.07
1.1
1.2
10.6
11.5
u/l
—
8
68
25
235
1.06
0.07
1.1
1.1
10.4
10.1
iu/ml
—
5
53
44
422
1.04
0.07
3.6
3.4
20.2
23.8
mg/l
0.43
30
253
96
984
0.97
0.07
1.5
1.4
—
—
—
0
0
8
91
0.88
0.06
1.0
1.0
—
—
—
0
0
27
285
0.95
0.06
1.3
1.2
1.0
11.6
u/ml
1.19
12
122
43
413
1.04
0.06
3.2
2.2
40.4
38.2
g/l
2.12
32
364
28
266
1.05
0.06
1.0
1.0
—
—
—
0
0
12
131
0.92
0.05
1.3
1.3
—
—
—
0
0
55
566
0.97
0.05
1.3
1.2
3.0
11.9
u/ml
—
7
91
15
161
0.93
0.05
1.4
1.2
—
—
—
0
0
59
575
1.03
0.04
1.3
2.3
10.4
21.8
e6/l
0.73
42
434
14
150
0.93
0.04
1.0
1.0
—
—
—
0
0
174
1720
1.01
0.04
1.4
1.4
—
—
—
0
0
59
576
1.02
0.04
1.4
2.3
1109.8
7658.1
e6/l
0.50
45
454
19
199
0.95
0.03
21.8
20.4
1201.8
1429.8
nmol/l
0.79
19
193
10
108
0.93
0.03
1.3
1.2
—
—
—
0
0
55
560
0.98
0.02
1.3
1.2
2.2
2.9
u/ml
—
5
60
19
198
0.96
0.02
16.3
14.2
680.6
810.4
nmol/l
0.75
19
190
24
232
1.03
0.02
2.0
1.4
—
—
—
0
0
10
93
1.08
0.02
1.0
1.2
—
—
—
0
0
53
521
1.02
0.02
3.5
2.1
6.6
7.4
g/l
2.87
35
409
53
521
1.02
0.02
3.5
2.1
—
—
—
0
0
12
113
1.06
0.01
2.0
1.8
—
—
—
0
0
40
408
0.98
0.01
3.2
2.3
0.0
0.0
g/l
0.26
34
382
17
163
1.04
0.01
1.1
1.4
1.5
1.5
nmol/l
0.01
17
148
20
207
0.97
0.01
1.1
1.1
—
—
—
0
0
51
516
0.99
0.00
2.9
3.6
2515.5
2800.5
u/ml
0.04
45
437
50
494
1.01
0.00
3.7
2.2
2.8
3.1
g/l
2.81
34
395
52
514
1.01
0.00
1.0
1.1
0.5
0.5
u/ml
0.01
12
155
114
1134
1.01
0.00
1.9
2.0
—
—
—
0
0
18
184
0.98
0.00
1.2
1.1
—
—
—
0
0
18
184
0.98
0.00
1.2
1.1
—
—
—
0
0
18
184
0.98
0.00
1.2
1.1
—
—
—
0
0
18
184
0.98
0.00
1.2
1.1
—
—
—
0
0
41
409
1.00
0.00
1.1
1.1
—
—
—
0
0
37
375
0.99
0.00
3.2
2.3
0.0
0.0
g/l
0.00
32
350
45
445
1.01
0.00
1.2
1.1
2.7
2.4
u/ml
0.12
19
208
38
377
1.01
0.00
3.2
2.3
0.0
0.0
g/l
0.00
32
351
29
292
0.99
0.00
1.8
2.1
—
—
—
0
0
61
606
1.01
0.00
1.1
1.1
4.5
5.6
u/ml
0.22
25
264
10
103
0.97
0.00
1.4
1.3
163.5
397.9
u/l
—
10
90
455
4551
1.00
0.00
1.5
1.5
—
—
—
0
0
25
249
1.00
0.00
1.1
1.1
—
—
—
0
0
61
615
0.99
0.00
2.0
1.6
90.0
106.5
u/ml
0.67
11
100
130
1304
1.00
0.00
1.6
1.6
—
—
—
0
0
56
560
1.00
0.00
1.1
1.1
4.1
6.9
u/ml
0.89
26
260
13
125
1.04
0.00
2.1
1.6
—
—
—
0
0
13
125
1.04
0.00
1.2
1.9
—
—
—
0
0
13
132
0.98
0.00
1.6
2.5
21.8
264.5
ug/l
0.69
13
116
21
215
0.98
0.00
1.3
1.3
1.2
0.7
u/ml
0.24
11
73
11
109
1.01
0.00
1.0
1.1
327.9
219.1
iu/ml
0.24
11
109
52
520
1.00
0.00
3.6
2.1
4.1
3.7
g/l
0.33
34
387
12
119
1.01
0.00
1.1
1.0
—
—
—
0
0
38
378
1.01
0.00
5.4
3.4
63.3
64.3
mg/l
0.01
25
299
38
378
1.01
0.00
5.4
3.4
46.2
40.4
mg/l
0.10
25
300
57
575
0.99
0.00
1.2
2.1
3.8
3.6
mmol/l
0.59
51
543
18
185
0.97
0.00
1.2
1.1
—
—
—
0
0
15
153
0.98
0.00
1.5
1.3
17324.0
80041.1
e6/l
—
10
104
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
9
97
0.93
0.00
1.1
1.1
206.3
82.3
u/l
—
9
85
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
5.3
—
0.3
—
0
6
7
72
0.97
0.00
3.0
2.9
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
9
94
0.96
0.00
1.1
1.1
15.4
16.4
u/l
—
9
81
0
6
0.00
0.00
0.0
5.0
—
—
—
0
0
8
86
0.93
0.00
2.1
4.1
—
—
—
0
0
0
5
0.00
0.00
0.0
3.4
—
—
—
0
0
5
50
1.00
0.00
4.8
5.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
2.6
—
0
7
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
10.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
8.0
—
0
8
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
5
56
0.89
0.00
1.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
7.8
—
97.3
—
0
6
Mortality – FinRegistry
↥Association
Association between endpoint Q17_CONGEN_MALFO_EYE_EAR_FACE_NECK and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| Q17_CONGEN_MALFO_EYE_EAR_FACE_NECK | 1.228 [1.05, 1.43] | 0.01 |
| Birth year | 0.989 [0.98, 1.0] | 0.01 |
During the follow-up period (1.1.1998 — 31.12.2019), 596 out of 19221 females with Q17_CONGEN_MALFO_EYE_EAR_FACE_NECK died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| Q17_CONGEN_MALFO_EYE_EAR_FACE_NECK | 1.217 [1.07, 1.39] | 0.003 |
| Birth year | 0.989 [0.98, 1.0] | 0.014 |
During the follow-up period (1.1.1998 — 31.12.2019), 742 out of 18380 males with Q17_CONGEN_MALFO_EYE_EAR_FACE_NECK died.
Mortality risk
Mortality risk for people of age
years, who have Q17_CONGEN_MALFO_EYE_EAR_FACE_NECK.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.12% | 0.234% |
| 5 | 0.592% | 1.33% |
| 10 | 1.52% | 3.435% |
| 15 | 2.831% | 6.677% |
| 20 | 4.722% | 12.141% |
Relationships between endpoints
↥Index endpoint: Q17_CONGEN_MALFO_EYE_EAR_FACE_NECK – Congenital malformations of eye, ear, face and neck
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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