Congenital lens malformations

Q17_CONGEN_LENS_MALFO

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — Q12 Cause of death: ICD-10 — Q12 2 out of 7 registries used, show all original rules.	178
4. Check minimum number of events None	178
5. Include endpoints None	178
6. Filter based on genotype QC (FinnGen only)	178

Control definitions (FinnGen only)

Control exclude: Q17_CONGEN_MALFO_EYE_EAR_FACE_NECK

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF4
Parent code in ICD-10: Q1
Name in latin: Malformationes congenitae lentis

NAME	Q17_CONGEN_LENS_MALFO
CONTROL_EXCLUDE	Q17_CONGEN_MALFO_EYE_EAR_FACE_NECK
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	Q12
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	Q12
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Congenital lens malformations based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	2183	1150	1030
Only index persons	1768	928	840
Unadjusted period prevalence (%)
Whole population	0.03	0.03	0.03
Only index persons	0.03	0.03	0.03
Median age at first event (years)
Whole population	10.95	12.13	9.56
Only index persons	18.23	19.68	16.63

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	178	114	64
Unadjusted period prevalence (%)	0.04	0.04	0.03
Median age at first event (years)	34.49	34.26	34.90

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
163: Matched controls
1630

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

Q12.0

ICD-10 Finland

Congenital cataract

+∞

199.6

148

Z96.1

ICD-10 Finland

Presence of intraocular lens

25.5

44.4

H27.0

ICD-10 Finland

Aphakia

+∞

32.4

CJE20

NOMESCO Finland

Phakoemulsification with implantation of artificial lens in posterior chamber

6.5

20.5

137

H26.4

ICD-10 Finland

After-cataract

13.7

20.5

CKD60

NOMESCO Finland

Anterior vitrectomy

119.6

20.1

S01CA01

ATC

dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)

5.1

19.4

254

74439

ICD-8 Finland

Congenital anomalies of eye, Cataracta NUD

+∞

17.0

7433A

ICD-9 Finland

Congenital anomalies of eye, Congenital cataract and lens anomalies

+∞

17.0

H55

ICD-10 Finland

Nystagmus and other irregular eye movements

176.0

15.8

CJB10

NOMESCO Finland

Laser discission of secondary cataract

10.9

15.5

ZXA00

NOMESCO Finland

Right side

4.5

14.9

194

WX140

NOMESCO Finland

Parabulbar anesthesy

17.9

14.4

XCD00

NOMESCO Finland

Clinical examination of eye in general anaesthesia

+∞

12.7

H54.2

ICD-10 Finland

Moderate visual impairment, binocular

140.2

12.6

114

Kela drug reimbursment

Glaucoma

9.3

12.1

H40.5

ICD-10 Finland

Glaucoma secondary to other eye disorders

50.7

12.1

H26.00

ICD-10 Finland

Infantile, juvenile and presenile cataract

+∞

11.6

TCG10

NOMESCO Finland

Removal of sutures from cornea

128.6

11.6

S01ED51

ATC

timolol, combinations; ophthalmic

9.7

11.5

XCW99

NOMESCO Finland

Other investigative procedure of eye

5.6

10.7

S01ED01

ATC

timolol; ophthalmic

11.8

10.6

H26.01

ICD-10 Finland

Infantile, juvenile and presenile cataract

117.1

10.5

Q12.1

ICD-10 Finland

Congenital displaced lens

+∞

10.5

H33.0

ICD-10 Finland

Retinal detachment with retinal break

25.3

10.4

CJF10

NOMESCO Finland

Secondary implantation of artificial lens in posterior chamber

+∞

9.5

3793A

ICD-9 Finland

Other disorders of eye, Aphakia and other disorders of lens[APHAKIA]

+∞

9.5

H27.1

ICD-10 Finland

Dislocation of lens

+∞

9.5

H53.0

ICD-10 Finland

Amblyopia ex anopsia

14.8

9.4

XCK10

NOMESCO Finland

Photography of fundus of eye

5.2

9.3

ZXA05

NOMESCO Finland

Left side

3.4

9.2

186

CKD65

NOMESCO Finland

Pars plana or pars plicata vitrectomy

25.7

9.0

H26.02

ICD-10 Finland

Presenil cataract

11.7

9.0

CJD20

NOMESCO Finland

Extracapsular cataract extraction with implantation of artificial lens in posterior chamber

94.6

8.5

ZXA10

NOMESCO Finland

Bilateral

3.4

8.3

159

S01BA04

ATC

prednisolone; ophthalmic (corticosteroids, plain)

18.3

8.2

S01EC01

ATC

acetazolamide; systemic

19.5

7.7

S01AX11

ATC

[U] ofloxacin; ophthalmic

8.3

7.6

S01EE01

ATC

latanoprost; ophthalmic

6.9

7.2

S01EC04

ATC

brinzolamide; ophthalmic

11.6

6.9

Z01.0

ICD-10 Finland

Examination of eyes and vision

3.1

6.6

139

S01EC03

ATC

dorzolamide; ophthalmic

72.5

6.5

H26.2

ICD-10 Finland

Complicated cataract

27.8

6.3

37872

ICD-8 Finland

Other diseases of eye, Aphakia artefacta, acquisita

+∞

6.3

3619

FHL

Other operations in this group, such as corneal refractive surgery

+∞

6.3

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3018418) pH of Serum or Plasma

359

1.86

3.48

5.5

3.7

7.4

0.33

(3033658) Prothrombin time (PT) actual/Normal

336

1.87

3.42

4.0

4.3

95.5

94.7

0.08

329

(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma

204

2.03

3.32

2.6

3.0

2.5

2.4

mmol/l

0.16

181

(3024561) Albumin [Mass/volume] in Serum or Plasma

507

1.75

3.18

6.7

4.6

35.4

36.8

g/l

1.03

480

(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma

158

2.08

3.03

2.3

4.7

23.5

6.6

umol/l

0.45

136

(3045788) Cell count panel - Pleural fluid

8.53

2.76

1.4

1.2

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

602

1.63

2.62

12.5

7.1

1.2

mmol/l

0.53

508

(3015377) Calcium [Moles/volume] in Serum or Plasma

406

1.68

2.57

4.4

3.2

2.4

mmol/l

0.09

359

(3012441) Differential panel - Pleural fluid

7.31

2.56

1.4

2.0

—

(3020717) Zinc [Moles/volume] in Serum or Plasma

5.60

2.56

1.2

1.1

13.9

20.1

umol/l

—

(3023368) Bacteria identified in Blood by Culture

296

1.75

2.54

5.7

3.8

—

(3032080) INR in Blood by Coagulation assay

436

1.65

2.47

7.4

6.3

1.0

1.1

inr

1.30

139

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

548

1.60

2.38

9.8

6.7

1.2

mmol/l

0.03

499

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

2.15

2.37

4.1

11.0

24.4

25.3

mmol/l

0.50

(3013290) Carbon dioxide [Partial pressure] in Blood

3.44

2.21

5.5

3.3

5.2

5.0

kpa

—

(3027315) Oxygen [Partial pressure] in Blood

3.44

2.21

5.5

3.3

9.9

8.8

kpa

—

(1616796) Gas panel - Central venous blood

3.79

2.17

5.6

3.2

—

(3019198) Lymphocytes [#/volume] in Blood

758

1.54

2.14

9.3

6.6

1.8

1.9

e9/l

0.84

671

(3013115) Eosinophils [#/volume] in Blood

749

1.54

2.13

9.0

6.9

0.2

e9/l

0.13

657

(3044941) Cell count panel - Synovial fluid

5.11

2.08

1.6

1.3

—

(3013826) Glucose [Moles/volume] in Serum or Plasma

771

1.53

2.08

9.1

4.6

6.5

6.4

mmol/l

0.05

697

(3016914) Bacteria identified in Cerebral spinal fluid by Culture

4.10

2.05

1.0

1.3

—

(3001604) Monocytes [#/volume] in Blood

725

1.52

2.03

8.4

6.7

0.6

0.5

e9/l

0.76

626

(3006315) Basophils [#/volume] in Blood

728

1.51

1.98

8.3

6.7

0.0

e9/l

0.05

629

(3013650) Neutrophils [#/volume] in Blood by Automated count

103

850

1.50

1.90

12.1

9.8

4.3

4.0

e9/l

0.41

727

(3007853) Bacteria identified in Skin by Aerobe culture

162

1.79

1.88

2.1

1.6

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

198

1.68

1.75

2.2

1.8

—

(3000991) Gas panel - Venous blood

120

1.85

1.71

7.5

9.1

—

(3026782) Osmolality of Urine

258

1.60

1.70

3.6

2.6

505.2

553.5

mosm/kgh2o

0.70

222

(42870588) Differential panel, method unspecified - Blood

482

1.48

1.64

9.7

6.6

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

244

1.60

1.62

1.2

1.3

55.8

36.3

iu/ml

—

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

120

1043

1.46

1.56

7.6

6.8

87.4

80.7

u/l

0.35

113

974

(3026008) Bacteria identified in Urine by Culture

395

1.49

1.56

2.9

2.7

—

(3013707) Erythrocyte sedimentation rate by Westergren method

119

1033

1.46

1.56

4.2

4.1

10.5

9.4

mm/h

0.51

111

951

(3018677) aPTT in Platelet poor plasma by Coagulation assay

180

1.66

1.55

2.3

2.7

30.3

29.6

0.27

175

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

133

1.75

1.51

2.5

1.7

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

159

1472

1.75

1.51

16.9

11.5

27.3

20.3

mg/l

1.37

132

1118

(40758558) Short blood count panel - Blood

371

1.48

1.50

7.4

7.1

—

(3007628) Bicarbonate [Moles/volume] standard in Venous blood

1.96

1.50

3.9

8.8

23.6

24.2

mmol/l

0.43

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

134

1.73

1.47

2.5

1.8

—

(3000850) Epithelial cells [#/volume] in Urine

276

1.53

1.46

4.0

2.5

7.0

5.5

e6/l

0.46

240

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

2.01

1.42

2.0

1.9

—

(36304419) Bacteria [Presence] in Urine

375

1.46

1.42

4.1

2.7

—

(3021960) Folate [Moles/volume] in Serum or Plasma

252

1.54

1.41

1.6

1.4

22.4

21.8

nmol/l

0.06

216

(3030467) Casts [#/volume] in Urine by Automated count

377

1.45

1.38

4.1

2.7

0.1

0.3

e6/l

1.89

270

(3024928) Oxygen saturation in Venous blood

2.55

1.31

2.7

9.9

—

(3018171) Choriogonadotropin [Units/volume] in Serum or Plasma

1.81

1.30

2.0

2.7

11327.1

3405.0

u/l

—

(44806118)

2.83

1.29

1.8

1.6

—

(44790047)

2.83

1.29

1.8

1.6

—

(44790049)

2.83

1.29

1.8

1.6

—

(3028192) IgG subclass 2 [Mass/volume] in Serum

2.83

1.29

1.2

1.4

2.2

2.0

g/l

—

(4062490)

2.83

1.29

1.2

1.4

—

(3027135) IgG subclass 1 [Mass/volume] in Serum

2.83

1.29

1.2

1.4

5.0

6.6

g/l

—

(3024139) IgG subclass 3 [Mass/volume] in Serum

2.83

1.29

1.2

1.4

0.3

g/l

—

(44790048)

2.83

1.29

1.8

1.6

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

448

1.40

1.24

2.3

1.7

99.1

95.6

pmol/l

0.27

237

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

126

1127

1.40

1.24

3.9

3.8

14.7

14.6

pmol/l

0.16

116

1024

(40761536) Microorganisms panel - Urine sediment

135

1.63

1.18

5.6

3.1

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

0.00

1.16

0.0

1.3

—

(3008295) Osmolality of Serum or Plasma

2.54

1.16

1.2

2.0

285.8

281.9

mosm/kgh2o

—

(3019230) Fractional oxyhemoglobin in Venous blood

2.54

1.16

2.4

11.2

73.4

65.1

—

(3030905) Polymorphonuclear cells [#/volume] in Blood

2.39

1.13

3.0

3.3

3.4

5.0

e9/l

—

(3032035) Polymorphonuclear cells/100 leukocytes in Blood

2.39

1.13

3.0

3.9

58.0

61.3

—

(36305247) Microscopic observation [Identifier] in Isolate by Gram stain

2.39

1.13

1.0

1.5

—

(40760892) CBC W Ordered Manual Differential panel - Blood

345

1.41

1.12

4.6

4.9

—

(3044290) Cell count panel - Cerebral spinal fluid

2.31

1.11

1.0

2.5

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

239

1.47

1.11

2.0

1.6

—

(3009542) Hematocrit [Volume Fraction] of Blood

151

1406

1.49

1.09

19.0

12.4

39.3

40.4

0.75

113

1131

(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma

1.79

1.06

2.0

3.1

25.7

5.0

ug/l

—

(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma

2.31

1.04

8.4

2.7

—

(3050238) Crystals [Presence] in Synovial fluid by Light microscopy

2.31

1.04

1.0

1.3

—

(3021589) Normoblasts [#/volume] in Blood

699

1.32

1.04

11.0

8.9

0.0

e9/l

0.56

560

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

142

1312

1.41

1.03

13.3

10.4

89.3

90.6

ml/min/173m2

0.21

114

1036

(3014111) Lactate [Moles/volume] in Serum or Plasma

108

1.63

1.01

6.8

8.9

1.4

1.1

mmol/l

0.84

101

(3027238) Thyroperoxidase Ab [Units/volume] in Serum or Plasma

109

1.62

0.97

1.2

183.6

150.6

iu/ml

—

(4094501)

0.00

0.96

0.0

1.1

—

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

1.77

0.94

16.2

7.1

—

(3007164) IgA [Mass/volume] in Serum or Plasma

375

1.34

0.92

1.4

1.5

1.8

2.2

g/l

1.39

218

(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma

661

1.29

0.90

5.3

6.4

21.1

10.7

umol/l

0.72

626

(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay

1.90

0.88

1.5

1.3

—

(3018095) Leukocytes [#/volume] in Urine

493

1.29

0.84

4.7

3.6

118.3

39.2

e6/l

0.62

327

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

307

1.35

0.83

2.2

2.3

—

(3002582) Erythrocytes [#/volume] in Urine

409

1.31

0.83

4.7

3.0

15.2

54.3

e6/l

1.51

305

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

131

1213

1.30

0.80

4.8

4.9

37.9

38.5

mmol/mol

0.34

119

1134

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

228

1.38

0.80

2.9

2.5

0.8

0.7

e6/l

0.20

125

(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection

1.79

0.77

1.7

1.6

—

(3009508) Creatinine [Moles/volume] in Urine

395

1.29

0.76

3.5

3.0

8.7

8.1

mmol/l

0.27

345

(4306422)

2.03

0.73

1.0

1.2

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

332

1.31

0.73

2.0

1.7

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

214

1.37

0.72

6.5

3.5

3104.6

135.3

ng/l

0.46

140

(3006418) Campylobacter sp identified in Tissue by Organism specific culture

1.78

0.72

1.0

1.2

—

(3019309) Folate [Moles/volume] in Red Blood Cells

188

1.38

0.71

2.0

1.6

1244.9

1245.4

nmol/l

0.00

146

(40768804) Tissue Pathology biopsy report

542

1.25

0.69

1.7

2.0

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

476

1.26

0.68

4.8

3.2

—

(3025839) Triglyceride [Moles/volume] in Serum or Plasma

363

0.76

0.64

1.7

1.2

1.4

mmol/l

0.69

303

(3028707) Methadone [Presence] in Urine by Screen method

1.59

0.61

1.9

2.1

—

(3035637) Corticotropin [Mass/volume] in Plasma

0.00

0.60

0.0

1.6

—

(3025271) CD3-CD16+CD56+ (Natural killer) cells [#/volume] in Blood

0.00

0.60

0.0

2.1

—

0.1

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

445

0.79

0.60

1.5

1.9

—

(3000492) Spirometry study

123

1.42

0.60

1.2

1.5

—

(3011412) CD3 cells [#/volume] in Blood

0.00

0.60

0.0

2.1

—

1.3

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

1.50

0.60

1.5

1.3

—

(3008037) Lactate [Moles/volume] in Venous blood

0.00

0.59

0.0

3.4

—

1.4

—

(3001405) CD3+CD8+ (T8 suppressor) cells [#/volume] in Blood

0.00

0.59

0.0

2.0

—

587.2

—

(3050129) First trimester maternal screen panel - Serum or Plasma

0.56

0.57

2.2

1.3

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

142

1.38

0.57

1.5

—

(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection

1.69

0.57

1.7

1.6

—

(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma

1.52

0.52

1.7

1.4

—

(36304997) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ and CD8+ T-cells [Units/volume] in Blood

1.52

0.52

1.2

1.5

—

0.0

—

(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma

1.52

0.52

1.7

1.4

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

310

1.24

0.51

1.9

2.3

0.9

1.3

mg/l

0.59

251

(40761511) CBC panel - Blood by Automated count

160

1547

1.34

0.51

15.0

10.1

—

(40768443) Skin Pathology biopsy report

1.52

0.51

1.1

—

(3002256) Pathology report gross observation

155

1.33

0.49

1.3

1.2

—

(44816559) Phosphatidylethanol [Mass/volume] in Blood

1.51

0.48

1.3

1.2

—

(3044889) 12 lead EKG panel

869

1.17

0.46

4.1

3.3

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

213

1.26

0.44

3.0

2.7

5.0

2.9

e6/l

0.47

113

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

131

1.33

0.44

3.8

7.3

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

1.63

0.43

1.6

2.2

—

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

1.42

0.42

1.1

1.3

—

(3029075) Extractable nuclear Ab panel - Serum

0.00

0.41

0.0

1.1

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

0.41

0.0

3.3

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

0.41

0.0

1.6

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.41

0.0

1.6

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

0.41

0.0

3.3

—

105.6

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.41

0.0

1.6

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

0.41

0.0

3.3

—

4.0

—

(3046294) Neutrophil cytoplasmic Ab.classic [Titer] in Serum

0.00

0.41

0.0

1.5

—

(3026493) Urate [Moles/volume] in Serum or Plasma

300

1.21

0.40

3.1

3.0

352.5

5252.4

umol/l

1.29

264

(3042111) Morphology [Interpretation] in Bone marrow Narrative

0.00

0.40

0.0

2.3

—

(3028167) CD3+CD4+ (T4 helper) cells [#/volume] in Blood

0.00

0.40

0.0

2.1

—

750.8

—

(3048689) Calprotectin [Mass/mass] in Stool

225

1.24

0.40

2.5

322.9

101.5

ug/g

0.45

165

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

140

1344

1.20

0.40

4.9

4.4

1.9

1.8

mu/l

0.09

131

1236

(3038515) Glucose [Moles/volume] in Venous blood

0.00

0.39

0.0

3.7

—

8.0

—

(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence

0.00

0.39

0.0

1.9

—

(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum

111

0.71

0.38

2.1

2.3

—

18.7

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

1.41

0.37

1.1

—

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

103

969

1.15

0.37

2.8

3.3

42.6

40.3

u/l

0.13

924

(4034850)

1.48

0.36

7.5

10.3

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

134

0.73

0.36

1.4

1.6

—

(3014765) Yersinia sp identified in Stool by Organism specific culture

1.44

0.36

1.0

1.2

—

(3024891) Influenza virus A+B Ag [Presence] in Specimen

1.44

0.36

1.3

1.1

—

(3052851) Hemolysis interference index of Serum or Plasma

1.44

0.36

1.5

3.2

—

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

1.44

0.36

1.0

1.9

—

(42529406) Shigella sp [Presence] in Stool by Culture

1.38

0.35

1.0

1.2

—

(40766189) Gliadin peptide IgG Ab [Units/volume] in Serum by Immunoassay

1.34

0.34

1.3

1.1

—

13.6

—

(3022621) pH of Urine by Test strip

0.69

0.34

2.3

1.9

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

325

0.84

0.33

2.8

2.5

—

(4035726)

101

1.31

0.32

1.5

1.4

—

(3012516) Albumin [Mass/volume] in Urine

317

1.17

0.31

3.9

3.2

31.1

67.7

mg/l

1.16

205

(3019225) pH of Specimen

106

0.74

0.30

16.1

4.5

—

(3020682) Albumin/Creatinine [Ratio] in Urine

330

1.15

0.28

5.5

4.0

11.2

mg/mmol

1.67

207

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

122

1.25

0.28

2.5

3.2

—

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

244

1.18

0.28

1.3

1.2

10.8

7.3

u/ml

—

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

292

1.16

0.27

4.1

3.5

922.8

1110.8

ng/l

0.20

242

(3004119) Hemoglobin [Mass/volume] in Venous blood

1.22

0.27

9.4

6.3

125.9

131.5

g/l

—

(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay

0.68

0.26

1.6

2.3

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

0.68

0.26

2.2

2.1

—

(21494755) Public health laboratory ask at order entry panel

179

1.20

0.26

1.1

1.3

—

(3037467) Urinalysis macro (dipstick) panel - Urine

101

967

1.10

0.23

5.3

4.2

—

(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum

1.29

0.23

1.0

1.3

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

107

1.23

0.22

1.1

1.0

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

443

1.11

0.22

3.0

3.4

24.2

25.2

ng/l

0.06

270

(3000060) B lymphocytes [#/volume] in Blood

0.00

0.21

0.0

3.1

—

263.3

—

(3000208) Alpha tocopherol [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

3.5

—

24.5

—

(40768441) Liver Pathology biopsy report

0.00

0.21

0.0

1.5

—

(3019601) Blood group antibody investigation [Interpretation] in Plasma or RBC

0.00

0.21

0.0

1.2

—

(3017817) Protein [Mass] in Urine collected for unspecified duration

0.00

0.21

0.0

5.6

—

(42868421) Varicella zoster virus IgM Ab [Presence] in Cerebral spinal fluid by Immunoassay

0.00

0.21

0.0

1.2

—

(3002823) Mycoplasma pneumoniae IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

0.21

0.0

1.0

—

(3035320) C reactive protein [Mass/volume] in Body fluid

0.00

0.21

0.0

1.4

—

(3007847) Interleukin 2 Receptor Soluble [Units/volume] in Serum or Plasma

0.00

0.21

0.0

1.8

—

812.1

—

(3037677) Mycoplasma pneumoniae IgM Ab [Titer] in Cerebral spinal fluid

0.00

0.21

0.0

1.1

—

(3030429) Borrelia sp DNA [Identifier] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.0

—

(3014702) Chromogranin A [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

4.0

—

1.3

—

(40761849) Varicella zoster virus IgG Ab [Units/volume] in Cerebral spinal fluid by Immunoassay

0.00

0.21

0.0

1.1

—

(21494434) Karyotype in Bone marrow

0.00

0.21

0.0

1.0

—

(3044212) Herpes simplex virus 1+2 IgM Ab [Presence] in Cerebral spinal fluid

0.00

0.21

0.0

1.3

—

(3048469) 10-Hydroxycarbazepine [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

2.2

—

52.1

—

(3035933) Granulocytes/100 leukocytes in Blood

0.00

0.21

0.0

1.0

—

(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.3

—

(3027953) Aldolase [Enzymatic activity/volume] in Serum or Plasma

0.00

0.21

0.0

1.7

—

5.1

—

(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.3

—

(44813793)

0.00

0.21

0.0

1.2

—

(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.3

—

(3034603) RHD gene allele [Genotype] in Blood or Tissue by Molecular genetics method Nominal

0.00

0.21

0.0

1.2

—

(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.3

—

(3034770) Mitochondria Ab [Titer] in Serum

1.17

0.21

1.0

1.5

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.21

0.0

4.1

—

124.2

—

(3025468) Yersinia sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.9

—

(3024522) Salmonella sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.9

—

(21493690) Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood

0.00

0.21

0.0

2.7

—

(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection

0.00

0.21

0.0

1.9

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

435

1.11

0.20

2.5

2.0

—

(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection

0.00

0.20

0.0

1.9

—

(3005988) Vibrio sp identified in Specimen by Organism specific culture

0.00

0.20

0.0

1.9

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

251

1.14

0.20

1.5

—

(3017895) Helicobacter pylori Ab [Units/volume] in Serum

1.23

0.20

1.5

1.6

—

(3004248) Sex hormone binding globulin [Moles/volume] in Serum or Plasma

1.21

0.20

1.0

1.4

36.2

33.9

nmol/l

—

(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma

397

1.11

0.20

2.8

2.2

56.0

56.7

u/l

0.04

370

(3045414) Leukocytes [Presence] in Urine

1.14

0.19

2.3

1.4

—

(3027273) Bicarbonate [Moles/volume] in Venous blood

1.14

0.19

15.2

3.9

24.4

24.7

mmol/l

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

1.14

0.19

2.2

1.8

—

(3044640) Blood type and Crossmatch panel - Blood

408

1.10

0.19

2.5

2.3

—

(3019060) Gas panel - Arterial blood

1.17

0.18

13.4

3.2

—

(1002224) Polysomnography panel

0.76

0.17

1.0

1.1

—

(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma

156

1535

1.13

0.16

11.4

9.1

26.9

26.1

u/l

0.22

147

1485

(3025941) Bacteria identified in Stool by Culture

1.13

0.16

1.3

1.2

—

(3001019) Free T4 and TSH panel - Serum or Plasma

1.12

0.16

1.1

1.7

—

(3042936) Bacteria identified in Isolate by Culture

178

1.14

0.16

2.8

1.8

—

(3000494) Fungus identified in Specimen by Culture

159

1.15

0.16

1.6

1.5

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

1.16

0.15

2.4

1.7

—

(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma

131

1.16

0.15

4.8

4.5

30.7

32.3

—

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

0.78

0.15

1.3

1.4

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

247

1.11

0.14

1.1

1.5

—

(3019832) Treponema pallidum Ab [Presence] in Serum

257

1.11

0.14

2.3

1.8

—

(3022313) Gas panel - Capillary blood

1.20

0.14

6.3

6.2

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

161

1.13

0.13

1.2

1.9

—

(3023024) Carbon dioxide [Partial pressure] in Capillary blood

104

1.16

0.12

6.8

5.5

5.3

5.1

kpa

0.24

(3021601) Nitrite [Presence] in Urine by Test strip

697

0.94

0.12

6.4

4.5

0.0

estimate

0.00

160

(40768797) Stomach Pathology biopsy report

172

1.12

0.12

1.3

1.2

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

192

1.11

0.11

4.7

3.8

15.8

21.7

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

418

1.07

0.11

1.7

1.4

0.6

1.6

u/ml

1.08

108

(3009261) Glucose [Presence] in Urine by Test strip

704

0.94

0.10

5.0

3.4

0.0

estimate

0.50

156

(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma

145

0.89

0.10

2.6

2.5

0.9

0.7

ug/l

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

1.04

0.09

1.2

1.5

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

130

1320

0.94

0.09

4.2

3.9

1.5

mmol/l

0.14

117

1240

(3011397) Hemoglobin [Presence] in Urine by Test strip

312

1.07

0.09

4.4

3.4

—

(3003327) Ova and parasites identified in Stool by Light microscopy

1.09

0.09

3.7

1.7

—

(3028626) Oxygen [Partial pressure] in Capillary blood

1.04

0.08

10.0

5.9

8.8

9.1

kpa

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

0.79

0.08

1.0

1.3

—

(1761868) Lipid panel - Serum or Plasma

499

0.95

0.08

2.8

2.5

—

(3008898) HLA-B27 [Presence]

1.06

0.07

1.0

1.1

—

(3020630) Protein [Mass/volume] in Serum or Plasma

0.87

0.07

4.3

2.3

64.1

65.3

g/l

—

(3011288) Drugs identified in Urine by Screen method

1.09

0.07

2.4

2.0

—

(3035350) Ketones [Presence] in Urine by Test strip

698

0.96

0.07

5.0

3.3

0.0

estimate

0.00

159

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

295

0.94

0.07

2.8

2.3

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

0.86

0.07

1.3

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

193

0.93

0.06

2.4

2.1

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

130

1316

0.95

0.06

3.9

5.9

5.7

mmol/l

0.50

118

1215

(40761535) Cells panel - Urine sediment

102

0.88

0.06

3.8

—

(3037522) Nuclear Ab [Titer] in Serum

207

1.07

0.06

1.3

1.4

200.0

458.3

titre

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

615

1.04

0.05

4.8

3.9

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

133

1344

0.96

0.05

4.5

4.2

2.8

mmol/l

0.19

123

1258

(3013512) EKG study

323

0.95

0.05

2.6

3.5

—

(3029937) Albumin [Presence] in Urine by Test strip

388

1.04

0.04

6.1

3.7

0.0

estimate

0.00

157

(3041096) Erythrocytes [Presence] in Urine by Automated

402

0.96

0.04

4.5

2.9

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

542

0.97

0.04

5.4

3.4

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

120

1190

1.03

0.02

3.9

3.6

—

(3003694) ABO and Rh group [Type] in Blood

429

0.97

0.02

1.6

—

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

132

1329

0.97

0.02

4.2

3.9

4.7

4.6

mmol/l

0.33

120

1255

(3027008) Opiates [Presence] in Urine

113

1.07

0.02

1.6

1.7

—

(3027944) Amphetamines [Presence] in Urine

113

1.07

0.02

1.6

1.7

—

(3000764) Benzodiazepines [Presence] in Urine

113

1.07

0.02

1.6

1.7

—

(3028300) Cannabinoids [Presence] in Urine

114

1.06

0.01

1.6

1.7

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

126

0.95

0.00

1.7

1.5

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

127

1264

1.02

0.00

3.8

3.6

1.3

mmol/l

0.39

115

1184

(3013742) Prealbumin [Mass/volume] in Serum or Plasma

126

1.03

0.00

2.5

3.3

0.2

g/l

0.34

116

(3016879) Cocaine [Presence] in Urine

107

1.03

0.00

1.6

1.7

—

(3022145) Colonoscopy Study observation

137

1.02

0.00

1.3

—

(36660697) Celiac disease serology panel - Serum

145

0.96

0.00

1.4

1.1

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

155

0.96

0.00

2.0

1.9

—

(4010399)

105

1.05

0.00

1.1

1.5

—

(21493195) Respiratory pathogens DNA and RNA tested for in Respiratory system specimen by NAA with probe detection

0.00

0.0

1.3

—

(3000108) Respiratory syncytial virus B RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.3

—

(3004588) Protein electrophoresis panel - Serum or Plasma

0.86

0.00

6.0

2.2

—

(3005156) Respiratory syncytial virus A RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.3

—

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

0.91

0.00

1.0

2.0

—

(40757349) CD3+CD4+ (T4 helper) cells/CD3+CD8+ (T8 suppressor cells) cells [# Ratio] in Blood

0.00

0.0

1.1

—

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

0.92

0.00

3.2

1.6

—

(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.2

—

(3045142) Bone marrow Pathology biopsy report

0.00

0.0

1.2

—

(3010838) Calcium [Moles/time] in 24 hour Urine

0.00

0.0

1.3

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

0.93

0.00

1.2

1.8

—

(37020957) Sapovirus genogroups I+II+IV+V RNA [Presence] in Stool by NAA with probe detection

0.00

0.0

2.0

—

(37020445) Astrovirus RNA [Presence] in Stool by NAA with probe detection

0.00

0.0

2.0

—

(3002670) Multiple inhalant allergen IgE Ab [Units/volume] in Serum

0.00

0.0

2.6

—

(3044927) Protein electrophoresis panel - Urine

0.00

0.0

1.2

—

(3018658) Beta 2 glycoprotein 1 IgG Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3036432) Mycobacterium tuberculosis genotype [Identifier] in Isolate

0.00

0.0

9.2

—

(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma

0.00

0.0

1.4

—

0.9

—

(3002619) Bacteria identified in Specimen by Culture

0.00

0.0

1.0

—

(37021247) Adenovirus 40+41 DNA [Presence] in Stool by NAA with probe detection

0.00

0.0

2.0

—

(46235128) Lupus anticoagulant aPTT and dRVVT screening panel W Reflex

0.00

0.0

1.3

—

(3016845) Adenovirus Ag [Presence] in Specimen by Immunofluorescence

0.00

0.0

1.2

—

(3009871) Measles virus Ab [Titer] in Serum

0.00

0.0

2.0

—

(3029493) Herpes virus 6 DNA [Presence] in Blood by NAA with probe detection

0.00

0.0

6.0

—

(3020393) Adenovirus Ag [Presence] in Stool

0.00

0.0

1.3

—

(3028334) Neisseria gonorrhoeae [Presence] in Specimen by Organism specific culture

0.00

0.0

1.4

—

(40758895) Direct antiglobulin test.complement C3d specific reagent [Presence] on Red Blood Cells

0.00

0.0

3.5

—

(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma

0.00

0.0

1.4

—

15.7

—

(3007695) Herpes simplex virus 2 IgG Ab [Presence] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma

0.00

0.0

1.4

—

(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.6

—

(3013566) Clostridioides difficile [Presence] in Stool by Organism specific culture

0.00

0.0

2.0

—

(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]

0.00

0.0

1.4

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

0.93

0.00

2.0

1.2

—

(42868415) European tick borne encephalitis virus IgM Ab [Presence] in Cerebral spinal fluid by Immunoassay

0.00

0.0

1.6

—

(42869547) Procollagen type III.N-terminal propeptide [Mass/volume] in Serum

0.00

0.0

1.1

—

10.6

—

(21491868) Cryoglobulin [Mass/volume] in Serum

0.00

0.0

1.0

—

(42868766) Dientamoeba fragilis DNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.2

—

(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma

1.01

0.00

2.4

1.9

—

(40758897) Direct antiglobulin test.IgG specific reagent [Presence] on Red Blood Cells

0.00

0.0

3.5

—

(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.0

—

(3031072) Herpes simplex virus 1 IgG Ab [Presence] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3023709) Somatotropin [Mass/volume] in Serum or Plasma

0.00

0.0

3.9

—

1.0

—

(3005011) Chlamydia sp Ab [Titer] in Serum

0.00

0.0

1.4

—

(3006653) Thiamine [Moles/volume] in Blood

0.00

0.0

2.2

—

151.4

—

(21494890) Protein electrophoresis panel - 24 hour Urine

0.00

0.0

5.0

—

(42868499) Enterovirus IgG Ab [Presence] in Cerebral spinal fluid by Immunoassay

0.00

0.0

1.2

—

(42869457) Rotavirus RNA [Identifier] in Stool by NAA with probe detection

0.00

0.0

2.0

—

(3001684) Respiratory syncytial virus Ag [Presence] in Specimen

0.00

0.0

1.1

—

(3008536) Aspergillus sp Ab [Presence] in Serum

0.00

0.0

1.6

—

(36306090) Helicobacter pylori [Presence] in Tissue by Organism specific culture

0.00

0.0

1.0

—

(40765096) Chromosome analysis panel by Banding

0.00

0.0

1.0

—

(3025378) Microscopic observation [Identifier] in Cervix by Cyto stain

0.00

0.0

1.2

—

(3017569) Oxygen content in Arterial blood

0.00

0.0

13.2

—

(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood

0.89

0.00

9.2

4.4

61.5

51.8

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

0.94

0.00

1.4

1.5

—

(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count

0.00

0.0

3.6

—

(3013727) Leukocytes other/100 leukocytes in Blood

0.00

0.0

4.0

—

51.0

—

(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH

0.00

0.0

1.1

—

Mortality – FinRegistry

↥

Association

Association between endpoint Q17_CONGEN_LENS_MALFO and mortality.

Females

Parameter	HR [95% CI]	p-value
Q17_CONGEN_LENS_MALFO	1.84 [1.35, 2.5]	< 0.001
Birth year	0.995 [0.99, 1.0]	0.26

During the follow-up period (1.1.1998 — 31.12.2019), 66 out of 1030 females with Q17_CONGEN_LENS_MALFO died.

Males

Parameter	HR [95% CI]	p-value
Q17_CONGEN_LENS_MALFO	1.74 [1.29, 2.34]	< 0.001
Birth year	0.982 [0.97, 0.99]	< 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 61 out of 909 males with Q17_CONGEN_LENS_MALFO died.

Mortality risk

Mortality risk for people of age

years, who have Q17_CONGEN_LENS_MALFO.

N-year risk	Females	Males
1	0.179%	0.298%
5	1.2%	1.783%
10	2.636%	4.544%
15	5.309%	8.245%
20	9.297%	13.429%

Relationships between endpoints

↥

Index endpoint: Q17_CONGEN_LENS_MALFO – Congenital lens malformations

GWS hits: 1

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Congenital lens malformations

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints