No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
400 |
4. Check minimum number of eventsNone |
400 |
5. Include endpointsNone |
400 |
6. Filter based on genotype QC (FinnGen only) |
371 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Similar endpoints
↥List of similar endpoints to
Prominent ears
based on the number of shared cases.
Similar with more cases:
- Other congenital malformations of ear
- Congenital malformations of eye, ear, face and neck
- Congenital malformations, deformations and chromosomal abnormalities
- Congenital malformations, deformations and chromosomal abnormalities
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 371 | 297 | 74 |
| Unadjusted period prevalence (%) | 0.09 | 0.11 | 0.03 |
| Median age at first event (years) | 12.55 | 12.54 | 12.56 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 400
- Matched controls
- 4000
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q17.5
ICD-10 Finland
Prominent ear
+∞
307.7
400
*
DAD30
NOMESCO Finland
Plastic repair of auricle
+∞
307.7
351
*
ZXA10
NOMESCO Finland
Bilateral
3.3
19.9
90
324
DAD10
NOMESCO Finland
Reconstruction of auricle
134.0
12.5
13
*
ZXE10
NOMESCO Finland
More than one and less than three hours
2.2
10.4
117
641
ZXD10
NOMESCO Finland
Scheduled procedure
1.9
7.6
124
766
N07BB01
ATC
disulfiram; oral
4.4
7.6
19
45
WX408
NOMESCO Finland
General anesthesy, balanced
1.9
6.0
89
528
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
114
825
1.53
3.50
1.6
1.5
97.38
96.99
pmol/l
0.03
60
460
13
49
2.71
2.65
3.4
5.4
367.85
396.25
umol/l
0.26
13
42
10
30
3.39
2.62
2.1
1.5
2.23
1.76
promille
—
5
23
46
296
1.63
2.32
1.6
1.6
900.27
1097.06
nmol/l
0.99
31
227
13
53
2.50
2.30
1.2
1.2
—
—
—
0
0
290
2616
1.39
2.30
2.9
2.7
5.31
5.45
mmol/l
1.60
263
2415
48
314
1.60
2.27
1.0
1.0
—
—
—
0
0
348
3255
1.53
2.18
9.1
8.9
20.38
19.14
mg/l
0.24
261
2435
184
1581
1.30
1.86
4.6
5.4
31.92
31.39
%
0.27
167
1508
181
1560
1.29
1.77
4.5
5.3
53.84
54.92
%
0.63
165
1486
9
36
2.53
1.75
1.1
1.1
—
—
—
0
0
284
2600
1.32
1.73
4.5
3.9
14.17
14.34
pmol/l
0.63
257
2392
277
2531
1.31
1.69
2.5
2.5
1.18
1.13
mmol/l
0.57
259
2392
140
1174
1.30
1.67
2.6
2.4
72.38
70.41
nmol/l
0.35
132
1090
244
2198
1.28
1.63
3.1
2.8
28.11
28.00
u/l
0.02
231
2112
15
78
1.96
1.56
1.9
1.9
1.83
4.25
ug/l
—
10
72
387
3757
1.93
1.54
13.8
13.1
4.54
4.55
e12/l
0.10
380
3670
387
3759
1.91
1.51
13.9
13.3
135.69
134.81
g/l
0.76
387
3717
96
780
1.30
1.43
4.0
6.3
1.03
1.08
inr
0.86
39
293
386
3752
1.82
1.41
13.8
13.2
265.34
262.44
e9/l
0.42
378
3661
386
3752
1.82
1.41
13.7
13.2
40.51
40.15
%
1.00
374
3590
7
29
2.44
1.40
1.4
1.1
—
—
—
0
0
82
654
1.32
1.39
3.6
2.2
8.42
20.89
ng/l
1.18
28
220
184
1625
1.25
1.37
2.8
3.1
0.00
0.00
estimate
-0.00
34
368
5
17
2.96
1.36
1.8
5.3
2.40
1.22
ug/l
—
5
17
14
75
1.90
1.36
1.2
1.2
—
—
—
0
0
10
47
2.16
1.34
2.7
2.2
107.03
197.72
ug/l
—
10
41
318
2995
1.30
1.33
5.3
4.5
1.71
1.72
mu/l
0.04
301
2826
122
1036
1.26
1.27
5.8
6.2
1.20
1.22
mmol/l
1.99
105
890
198
1773
1.23
1.27
6.1
7.6
4.06
3.87
e9/l
0.50
173
1546
30
204
1.51
1.26
2.8
5.3
5.96
5.80
kpa
0.40
30
199
106
887
1.27
1.25
3.0
3.2
0.00
0.01
estimate
0.80
33
361
110
925
1.26
1.25
5.5
6.1
1.20
1.22
mmol/l
1.72
103
846
211
1907
1.23
1.23
2.9
2.8
57.93
55.42
ug/l
0.12
197
1784
14
78
1.82
1.22
4.6
11.9
1.81
1.34
%
0.60
14
78
14
78
1.82
1.22
4.6
11.9
0.76
0.70
%
0.20
14
78
242
2219
1.23
1.22
3.0
3.5
35.75
36.42
mmol/mol
0.53
225
2103
342
3263
1.33
1.22
4.3
4.2
—
—
—
0
0
5
19
2.65
1.22
1.0
1.0
—
—
—
0
0
25
166
1.54
1.18
3.0
8.2
5.12
6.00
mmol/l
0.90
25
161
26
175
1.52
1.16
3.0
7.5
25.42
24.47
mmol/l
0.92
26
175
5
20
2.52
1.15
1.4
1.2
—
—
—
0
0
289
2708
1.24
1.15
2.9
2.8
2.81
2.78
mmol/l
0.28
275
2556
24
160
1.53
1.12
1.2
1.6
—
—
—
0
0
29
202
1.47
1.11
2.9
5.4
2.10
1.14
mmol/l
1.22
23
151
182
1633
1.21
1.10
3.8
4.3
0.00
0.00
estimate
-0.00
36
366
113
967
1.23
1.09
1.5
1.6
—
—
—
0
0
5
21
2.40
1.09
1.0
1.2
—
—
—
0
0
165
1468
1.21
1.09
2.5
2.5
—
—
—
0
0
7
32
2.21
1.08
1.3
1.2
—
—
—
0
0
318
3022
1.26
1.05
10.7
11.0
13.70
13.70
%
0.01
311
2968
183
1649
1.20
1.05
2.8
3.1
0.00
0.00
estimate
-0.00
35
356
5
22
2.29
1.03
1.4
1.1
—
—
—
0
0
12
68
1.79
1.01
2.1
4.9
0.61
0.71
%
0.58
12
68
13
76
1.73
1.00
4.8
12.2
92.34
94.72
%
0.45
13
76
141
1246
1.20
0.98
2.9
3.0
—
—
—
0
0
92
779
1.24
0.98
2.0
1.8
—
—
—
0
0
12
69
1.76
0.97
1.8
1.6
6.23
6.72
mmol/l
0.76
12
69
10
54
1.87
0.97
1.3
1.2
—
—
—
0
0
124
1087
1.20
0.94
1.3
1.4
3.10
1.98
u/ml
0.24
35
282
285
2692
1.20
0.92
2.8
2.8
4.60
4.61
mmol/l
0.06
273
2556
283
2672
1.20
0.92
2.9
2.7
1.44
1.48
mmol/l
1.14
268
2534
7
126
0.55
0.90
1.0
1.4
—
—
—
0
0
28
205
1.39
0.86
4.5
3.9
—
—
—
0
0
149
1338
1.18
0.85
2.3
2.3
—
—
—
0
0
6
31
1.95
0.84
1.2
1.3
—
—
—
0
0
21
146
1.46
0.84
1.0
1.1
2.18
1.41
u/ml
0.37
13
85
6
32
1.89
0.82
1.2
1.3
—
—
—
0
0
25
182
1.40
0.80
2.6
3.6
0.21
0.23
g/l
0.60
25
171
21
148
1.44
0.79
2.7
6.1
24.00
23.35
mmol/l
0.50
21
148
0
26
0.00
0.78
0.0
1.6
—
—
—
0
0
5
100
0.49
0.78
1.4
2.3
—
—
—
0
0
25
183
1.39
0.78
1.2
1.5
2.98
3.71
mg/l
0.28
19
113
110
970
1.18
0.78
2.0
2.0
—
—
—
0
0
38
298
1.30
0.77
2.4
2.1
2.52
2.52
g/l
0.03
32
271
226
2111
1.16
0.77
3.3
3.4
6.95
7.78
mm/h
0.94
211
1941
209
1941
1.16
0.77
5.8
5.6
76.36
74.36
u/l
0.22
192
1811
6
34
1.78
0.76
2.2
1.7
0.17
0.18
e9/l
—
6
27
85
736
1.20
0.73
3.2
2.3
49.28
55.50
u/l
1.42
80
672
31
238
1.33
0.73
1.4
1.6
18.83
13.47
iu/l
0.36
23
186
338
3268
1.22
0.73
7.4
7.0
25.90
24.17
u/l
0.53
323
3145
55
456
1.24
0.73
1.3
1.3
21.24
19.68
nmol/l
0.44
49
404
305
2923
1.18
0.72
8.9
7.9
139.43
139.41
mmol/l
0.04
295
2812
22
160
1.40
0.72
5.7
5.5
0.56
0.77
mmol/l
0.11
17
113
5
27
1.86
0.68
1.0
2.3
—
—
—
0
0
305
2930
1.17
0.67
8.8
7.9
3.85
3.88
mmol/l
0.84
294
2804
27
207
1.33
0.65
1.3
1.2
—
20.28
—
0
11
37
297
1.27
0.65
1.4
1.4
188.67
284.27
miu/ml
0.88
18
158
5
29
1.73
0.64
1.0
1.1
1812.00
1640.14
miu/ml
—
5
29
22
164
1.36
0.64
1.0
1.1
2.36
3.53
u/ml
0.25
14
94
46
381
1.23
0.63
1.2
1.3
242.96
146.85
iu/ml
0.52
21
147
5
30
1.67
0.61
1.0
1.3
—
—
—
0
0
0
23
0.00
0.58
0.0
1.5
—
—
—
0
0
11
161
0.67
0.58
1.3
1.3
—
—
—
0
0
6
35
1.72
0.58
1.5
1.2
—
—
—
0
0
6
35
1.72
0.58
1.5
1.2
—
—
—
0
0
6
35
1.72
0.58
2.2
1.7
427.67
521.22
e6/l
—
6
27
6
35
1.72
0.58
1.5
1.2
—
—
—
0
0
96
859
1.15
0.57
4.6
4.5
37.34
37.84
g/l
0.39
85
799
6
36
1.68
0.57
1.5
1.2
—
—
—
0
0
6
36
1.68
0.57
1.8
1.4
—
—
—
0
0
6
36
1.68
0.57
1.5
1.2
—
—
—
0
0
6
36
1.68
0.57
1.5
1.2
—
—
—
0
0
48
405
1.21
0.56
1.4
1.5
440.93
37989253.01
pmol/l
0.80
43
358
8
122
0.65
0.55
1.3
1.8
1.02
1.19
g/l
—
8
114
167
1554
1.13
0.55
4.8
4.4
5.89
6.09
mmol/l
0.80
149
1328
6
40
1.51
0.52
1.0
1.1
—
—
—
0
0
63
554
1.16
0.48
2.1
1.5
1.45
1.32
%
0.63
55
512
8
120
0.66
0.46
1.3
1.8
0.17
0.23
g/l
—
8
114
26
211
1.25
0.45
1.0
1.2
—
—
—
0
0
10
69
1.46
0.44
1.2
1.1
—
—
—
0
0
15
196
0.76
0.44
2.0
3.3
229.07
219.19
u/l
0.10
15
191
16
207
0.76
0.44
1.8
1.4
—
—
—
0
0
5
32
1.57
0.42
2.2
1.5
5.10
5.01
mmol/l
—
5
32
5
32
1.57
0.42
2.0
1.9
777.20
712.25
e6/l
—
5
32
5
32
1.57
0.42
2.0
2.1
12.20
9.41
%
—
5
32
13
96
1.37
0.42
2.0
2.1
—
—
—
0
0
46
400
1.17
0.41
1.4
1.4
—
—
—
0
0
0
16
0.00
0.41
0.0
1.6
—
—
—
0
0
0
16
0.00
0.41
0.0
1.6
—
—
—
0
0
0
17
0.00
0.40
0.0
7.8
—
37.20
—
0
5
47
410
1.17
0.40
1.4
1.9
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
57
506
1.15
0.39
1.3
1.2
3.56
8.05
u/ml
0.78
25
210
5
36
1.39
0.38
1.0
1.1
—
—
—
0
0
80
729
1.12
0.38
3.4
3.0
1.02
1.02
kg/l
—
6
103
20
161
1.25
0.38
4.0
7.7
1.44
1.34
mmol/l
0.19
20
155
15
116
1.30
0.37
1.3
1.4
—
—
—
0
0
5
37
1.36
0.37
1.0
1.1
—
—
—
0
0
22
180
1.24
0.36
2.5
7.0
103.82
105.08
mmol/l
0.67
22
180
104
964
1.11
0.36
3.1
2.9
30.95
27.33
u/l
0.51
95
912
36
415
0.85
0.36
1.6
1.6
—
—
—
0
0
277
2688
1.10
0.36
6.6
6.7
102.81
103.27
ml/min/173m2
0.14
200
2040
78
716
1.11
0.33
3.0
2.5
2.33
2.35
mmol/l
0.84
63
642
7
96
0.72
0.31
1.3
1.3
39.57
46.87
pmol/l
—
7
91
38
335
1.15
0.30
1.8
1.7
—
—
—
0
0
7
55
1.28
0.30
1.0
1.1
—
—
—
0
0
94
877
1.09
0.29
2.3
3.1
—
—
—
0
0
27
312
0.86
0.29
3.6
3.5
3.95
7.58
umol/l
1.60
22
246
72
665
1.10
0.28
1.6
1.9
0.81
1.04
mg/l
0.31
50
451
8
64
1.26
0.27
1.3
5.6
—
974.33
—
0
6
131
1376
0.93
0.26
1.8
1.8
—
—
—
0
0
9
72
1.26
0.26
2.7
2.1
—
—
—
0
0
56
515
1.10
0.24
1.3
1.2
26.29
17.36
iu/ml
—
9
148
45
410
1.11
0.23
1.9
2.7
3.34
4.85
e6/l
0.46
22
223
15
125
1.21
0.22
1.1
1.1
—
—
—
0
0
160
1541
1.06
0.22
2.5
2.6
—
—
—
0
0
123
1175
1.07
0.22
4.7
5.0
10.23
10.48
umol/l
0.07
111
1097
5
41
1.22
0.22
1.0
1.1
—
—
—
0
0
76
713
1.08
0.22
1.9
1.9
—
—
—
0
0
5
42
1.19
0.21
1.0
1.4
—
—
—
0
0
5
42
1.19
0.21
1.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
4.2
—
153.63
—
0
11
0
11
0.00
0.21
0.0
2.0
—
—
—
0
0
0
12
0.00
0.21
0.0
2.7
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.7
—
—
—
0
0
0
12
0.00
0.21
0.0
1.7
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.7
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
6
48
1.25
0.20
1.0
1.3
—
—
—
0
0
6
48
1.25
0.20
1.0
1.3
—
—
—
0
0
9
115
0.78
0.20
3.7
3.5
3.44
3.43
g/l
—
9
110
6
49
1.23
0.20
1.5
1.2
—
—
—
0
0
12
99
1.22
0.20
1.0
1.2
—
—
—
0
0
19
165
1.16
0.19
1.4
1.7
—
—
—
0
0
45
415
1.10
0.19
1.8
2.6
1.16
0.75
e6/l
0.45
21
226
24
213
1.13
0.19
1.5
1.6
11.08
7.99
u/l
0.46
19
170
6
53
1.13
0.18
1.0
1.5
—
—
—
0
0
5
70
0.71
0.17
1.2
1.1
—
—
—
0
0
82
858
0.94
0.15
1.5
1.6
—
—
—
0
0
12
102
1.18
0.15
1.0
1.2
—
—
—
0
0
57
538
1.07
0.15
1.9
2.5
44.74
10.61
e6/l
0.48
45
466
12
103
1.17
0.14
2.0
2.1
—
—
—
0
0
8
97
0.82
0.14
1.6
1.7
48.75
40.52
u/l
—
8
90
8
98
0.81
0.14
1.1
1.5
—
—
—
0
0
57
540
1.06
0.13
2.1
2.4
14777.45
4920.37
u/l
0.79
22
230
26
238
1.10
0.13
3.1
2.5
32.78
32.49
%
0.03
18
175
30
277
1.09
0.13
2.4
3.3
372.10
447.57
ng/l
0.19
25
206
9
109
0.82
0.13
2.2
1.9
—
—
—
0
0
21
190
1.11
0.13
1.7
1.5
—
—
—
0
0
80
768
1.05
0.13
2.3
2.2
2.24
2.52
mg/l
1.08
66
652
74
709
1.05
0.12
2.0
2.9
1.38
0.20
e6/l
0.74
50
511
40
425
0.93
0.12
1.4
1.5
—
—
—
0
0
13
114
1.15
0.12
3.7
3.4
14.65
22.28
%
—
5
35
24
221
1.09
0.11
1.9
2.1
—
—
—
0
0
23
213
1.08
0.09
1.6
1.5
—
—
—
0
0
37
351
1.06
0.09
1.5
1.5
—
—
—
0
0
5
65
0.77
0.08
1.8
1.6
13.32
12.97
%
—
5
65
7
68
1.03
0.08
8.4
12.0
24.84
23.42
mmol/l
—
7
63
41
427
0.96
0.07
1.4
1.5
—
—
—
0
0
41
427
0.96
0.07
1.4
1.5
—
—
—
0
0
41
426
0.96
0.06
1.4
1.5
—
—
—
0
0
14
129
1.09
0.05
5.6
5.8
57.07
64.75
ng/l
0.24
14
122
21
198
1.06
0.05
3.1
2.7
4.13
4.91
umol/l
0.35
15
153
13
140
0.93
0.04
1.8
1.8
100.80
93.28
ml/min/173m2
—
5
47
12
111
1.08
0.04
1.1
1.1
—
—
—
0
0
30
311
0.96
0.04
2.1
2.8
29.34
29.38
s
0.01
30
301
34
330
1.03
0.03
1.4
1.3
—
—
—
0
0
11
102
1.08
0.03
6.5
6.1
9.35
9.45
kpa
0.08
11
97
22
211
1.05
0.03
1.5
1.5
—
—
—
0
0
15
142
1.06
0.02
2.3
1.5
—
—
—
0
0
56
550
1.02
0.02
1.3
1.5
—
—
—
0
0
32
312
1.03
0.02
3.0
2.1
2.39
2.39
mmol/l
0.05
24
264
48
487
0.98
0.01
1.7
2.6
317.56
5205.09
umol/l
2.07
43
451
16
154
1.04
0.00
2.9
2.0
93.25
50.14
u/ml
0.25
16
145
22
214
1.03
0.00
2.5
2.3
—
—
—
0
0
38
386
0.98
0.00
1.8
1.7
—
—
—
0
0
40
402
0.99
0.00
3.4
4.3
20.16
14.58
mg/mmol
0.17
25
278
17
173
0.98
0.00
1.6
1.6
—
—
—
0
0
61
605
1.01
0.00
1.5
1.6
1.39
1.26
mmol/l
0.53
55
538
48
475
1.01
0.00
1.5
1.5
—
—
—
0
0
14
136
1.03
0.00
1.2
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
10
100
1.00
-0.00
1.7
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
9.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.2
—
22.67
—
0
6
6
59
1.02
-0.00
1.5
1.3
—
—
—
0
0
34
340
1.00
-0.00
1.9
2.5
976.08
862.89
ng/l
0.06
12
137
0
7
0.00
-0.00
0.0
1.0
—
51.70
—
0
7
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
55
0.91
-0.00
2.4
2.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.6
—
—
—
0
0
6
59
1.02
-0.00
1.5
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
0.02
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
39.14
—
0
8
0
8
0.00
-0.00
0.0
5.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
6.33
—
0
8
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
5.71
—
0
7
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: Q17_PROMINENT_EARS – Prominent ears
GWS hits: 2
This endpoint is excluded (different definition than used in FinnGen).