No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleonly females |
293373 |
2. Check conditionsNone |
293373 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
482 |
4. Check minimum number of eventsNone |
482 |
5. Include endpointsNone |
482 |
6. Filter based on genotype QC (FinnGen only) |
482 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- First used in FinnGen datafreeze
- DF7
Similar endpoints
↥List of similar endpoints to
HSIL lesion of the vagina
based on the number of shared cases.
Similar with more cases:
- All dysplastic lesions of the vagina
- HSIL lesion of the cervix uteri, vagina or vulva
- All dysplastic lesions of the cervix uteri, vagina or vulva
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2714 | 2714 | - |
| Only index persons | 2571 | 2571 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.08 | 0.08 | - |
| Only index persons | 0.09 | 0.09 | - |
| Median age at first event (years) | |||
| Whole population | - | 49.94 | - |
| Only index persons | - | 48.76 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 482 | 482 | - |
| Unadjusted period prevalence (%) | 0.16 | 0.16 | - |
| Median age at first event (years) | 49.80 | 49.80 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 427
- Matched controls
- 4268
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
N89.1
ICD-10 Finland
Moderate vaginal dysplasia
+∞
299.5
251
*
LEB30
NOMESCO Finland
Destruction of lesion of vaginal mucosa
480.7
220.9
203
8
ULA02
NOMESCO Finland
Kolposcopy
38.4
220.8
335
369
N89.2
ICD-10 Finland
Severe vaginal dysplasia, not elsewhere classified
+∞
207.8
182
*
LEB00
NOMESCO Finland
Biopsy of vagina
118.1
206.3
214
36
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
23.7
172.4
295
368
LDA20
NOMESCO Finland
Biopsy of vaginal cervix
18.2
123.4
213
221
8077/2-C52.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of vagina, NOS
+∞
114.9
105
*
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
12.1
110.8
251
449
LDC03
NOMESCO Finland
Conisation of cervix uteri using diathermy or laser
14.3
75.5
137
136
N89.0
ICD-10 Finland
Mild vaginal dysplasia
131.6
72.6
76
7
N87.0
ICD-10 Finland
Mild cervical dysplasia
21.0
58.2
88
52
LDA10
NOMESCO Finland
Curettage of cervix uteri
11.5
58.1
116
134
A63.0
ICD-10 Finland
Anogenital (venereal) warts
14.9
51.5
89
74
N87.1
ICD-10 Finland
Moderate cervical dysplasia
14.7
46.7
81
67
LFB00
NOMESCO Finland
Biopsy of vulva or perineum
14.0
43.1
76
65
N87.2
ICD-10 Finland
Severe cervical dysplasia, not elsewhere classified
11.7
35.6
68
68
N90.1
ICD-10 Finland
Moderate vulvar dysplasia
122.8
32.2
34
*
LDB20
NOMESCO Finland
Electrocoagulation or laser therapy of cervix uteri
24.4
31.2
44
20
N90.2
ICD-10 Finland
Severe vulvar dysplasia, not elsewhere classified
+∞
29.5
28
*
8077/2-C53.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of cervix uteri
12.7
25.6
46
40
LEB10
NOMESCO Finland
Excision of lesion of vagina
28.7
23.9
32
12
LFB20
NOMESCO Finland
Destruction of lesion of vulva or perineum
25.4
23.8
33
14
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
2.7
21.4
218
1181
ZXC10
NOMESCO Finland
Use of laser
9.9
17.5
35
38
D07.2
ICD-10 Finland
Carcinoma in situ: Vagina
+∞
16.8
16
*
N90.0
ICD-10 Finland
Mild vulvar dysplasia
62.4
15.9
18
*
LFB10
NOMESCO Finland
Excision of lesion of vulva or perineum
14.7
15.2
25
18
R87.5
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal microbiological findings
13.1
15.1
26
21
6230B
ICD-9 Finland
Noninflammatory disorders of vagina, Dysplasia of vagina[DYSPLASIA VAGINAE MODERATA]
+∞
13.6
13
*
8077/2-C51.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of vulva, NOS
+∞
12.6
12
*
D06BB10
ATC
imiquimod; topical
4.7
11.2
38
87
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.9
9.3
275
2073
ZXC00
NOMESCO Finland
Use of diathermy
16.0
9.1
14
9
8325
FHL
Coagulation, cryo or laser in anesthesia or operating room
34.0
8.1
10
*
0781C
ICD-9 Finland
Other diseases due to viruses and Chlamydiae, Viral warts[CONDYLOMA ACCUMINATUM]
11.1
7.8
14
13
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.9
7.5
136
851
D06BB04
ATC
podophyllotoxin; topical
3.3
7.3
35
111
D07.1
ICD-10 Finland
Carcinoma in situ: Vulva
+∞
7.3
7
*
C52.91
ICD-10 Finland
Squamous cell carcinoma of the vagina
+∞
7.3
7
*
6230C
ICD-9 Finland
Noninflammatory disorders of vagina, Dysplasia of vagina[DYSPLASIA VAGINAE GRAVIS]
+∞
7.3
7
*
8070/3-C52.9
ICD-O-3
Squamous cell carcinoma, NOS, of vagina, NOS
+∞
7.3
7
*
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
2.4
7.0
59
265
8326
FHL
Batch conization
17.0
6.8
10
6
XXA00
NOMESCO Finland
Clinical examination requiring general anaesthesia
17.0
6.8
10
6
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
6.1
6.7
17
29
C539, 6666, 0
ICD-O-3
NA
5.5
6.5
18
34
R87.7
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal histological findings
14.6
6.4
10
7
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
8.3
6.4
13
16
L04AA06
ATC
mycophenolic acid; systemic
6.1
6.4
16
27
LEC00
NOMESCO Finland
Partial excision of vagina
27.1
6.2
8
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.7
6.1
160
1106
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
51
26
21.82
66.86
4.7
1.5
—
—
—
0
0
280
1114
4.61
61.00
3.2
1.4
—
—
—
0
0
116
253
5.72
52.69
3.5
1.4
—
—
—
0
0
64
306
2.26
7.67
1.8
1.6
—
—
—
0
0
53
241
2.35
7.13
1.8
1.5
—
—
—
0
0
248
1928
1.59
5.85
4.0
3.9
—
—
—
0
0
36
152
2.48
5.70
5.2
1.8
—
—
—
0
0
242
1881
1.58
5.65
2.9
2.3
80.0
78.4
nmol/l
0.42
223
1689
12
25
4.90
5.52
1.7
1.7
805.4
913.4
e6/l
—
5
10
31
128
2.52
5.16
1.7
2.4
1.5
1.5
g/l
0.07
25
112
63
349
1.93
5.11
5.9
4.1
249.1
237.4
u/l
0.30
57
332
15
41
3.74
4.96
1.5
1.1
45.6
68.7
u/ml
—
5
6
211
1630
1.52
4.82
6.4
4.1
36.0
36.0
g/l
0.05
193
1515
130
909
1.59
4.61
1.5
1.5
20.7
22.2
nmol/l
0.49
112
770
134
953
1.56
4.39
2.4
2.1
—
—
—
0
0
254
2083
1.46
4.11
4.5
3.6
0.0
0.0
estimate
0.80
41
386
29
132
2.27
3.94
1.6
1.2
4.5
2.0
u/ml
—
8
16
15
49
3.13
3.84
1.1
1.1
—
—
—
0
0
29
135
2.22
3.75
1.6
1.2
2.7
12.5
u/ml
—
10
28
146
1090
1.49
3.74
4.9
3.9
0.0
0.0
estimate
0.80
38
395
81
533
1.62
3.64
1.7
2.0
—
—
—
0
0
97
667
1.57
3.63
1.7
1.7
1147.8
1225.0
nmol/l
0.38
79
499
249
2065
1.43
3.62
5.7
4.9
0.0
0.0
estimate
0.50
39
393
144
1079
1.48
3.61
4.2
3.7
13.1
5.5
mg/mmol
0.62
75
614
355
3147
1.49
3.57
5.5
4.1
13.2
11.6
mm/h
1.33
329
2908
82
549
1.59
3.43
2.2
1.8
—
—
—
0
0
74
486
1.62
3.35
3.8
4.1
33.0
33.2
%
0.07
54
311
11
32
3.49
3.35
1.2
1.3
—
—
—
0
0
353
3142
1.46
3.34
10.2
7.0
74.0
76.6
u/l
0.74
342
2927
73
483
1.60
3.21
1.7
1.9
—
—
—
0
0
245
2056
1.39
3.18
4.5
3.5
0.0
0.0
estimate
0.00
39
394
120
892
1.46
3.08
5.4
3.8
1.0
1.0
kg/l
0.69
12
114
195
1599
1.37
2.82
2.0
1.9
105.8
100.1
pmol/l
0.62
101
772
15
59
2.59
2.81
1.3
1.3
—
—
—
0
0
41
241
1.77
2.81
11.8
6.1
10.1
8.2
mmol/l
1.25
41
229
17
75
2.31
2.54
1.8
1.7
—
—
—
0
0
170
1386
1.35
2.49
3.4
3.2
23.2
27.4
ng/l
0.29
96
850
274
2396
1.33
2.48
12.1
8.8
3.9
3.9
e9/l
0.00
251
2115
210
1768
1.33
2.47
7.0
4.9
1.2
1.2
mmol/l
0.17
189
1595
41
251
1.69
2.46
2.0
1.5
—
—
—
0
0
125
972
1.39
2.46
3.1
2.4
315.8
7188.9
umol/l
4.99
111
843
55
365
1.57
2.41
2.0
1.7
—
—
—
0
0
49
317
1.61
2.39
4.7
2.9
124.7
75.4
ng/l
1.82
44
284
8
22
3.68
2.37
1.4
1.8
—
—
—
0
0
68
479
1.49
2.28
9.0
5.6
—
—
—
0
0
6
13
4.66
2.28
1.2
1.3
—
—
—
0
0
133
1057
1.36
2.27
1.3
1.3
1.8
2.1
u/ml
0.10
37
291
54
365
1.54
2.20
2.1
1.8
—
—
—
0
0
119
935
1.36
2.18
3.1
2.9
828.7
1029.8
ng/l
0.54
98
780
7
19
3.72
2.16
1.7
1.2
—
—
—
0
0
7
19
3.72
2.16
1.7
1.2
—
—
—
0
0
6
14
4.33
2.15
1.8
1.1
—
—
—
0
0
6
14
4.33
2.15
1.8
1.1
—
—
—
0
0
172
1434
1.31
2.10
3.5
3.2
2.4
2.4
mmol/l
0.62
143
1257
39
247
1.63
2.09
1.8
1.5
—
—
—
0
0
18
89
2.06
2.08
1.7
1.2
—
—
—
0
0
30
177
1.74
2.07
1.7
1.6
—
—
—
0
0
5
10
5.04
2.07
1.6
2.3
—
—
—
0
0
227
1970
1.29
2.03
8.8
5.6
1.2
1.2
mmol/l
0.06
197
1653
9
32
2.85
2.01
2.0
1.6
1.0
1.0
g/l
—
9
32
143
1171
1.31
1.97
2.0
2.0
112.2
131.6
u/l
0.79
135
1106
44
292
1.56
1.96
6.0
2.8
1.3
2.4
mmol/l
1.56
38
236
7
22
3.21
1.88
1.7
3.3
—
—
—
0
0
122
983
1.32
1.88
3.1
2.2
2.7
3.0
mg/l
0.96
109
839
95
738
1.36
1.86
2.8
2.7
2.5
2.4
mmol/l
0.41
79
647
20
109
1.87
1.80
1.8
1.2
51.5
26.3
u/ml
—
6
9
24
142
1.73
1.68
2.1
1.7
—
—
—
0
0
6
19
3.18
1.66
1.0
1.1
—
—
—
0
0
50
355
1.46
1.65
6.3
6.7
1.0
1.5
mmol/l
0.51
39
291
25
151
1.69
1.63
2.4
1.8
—
—
—
0
0
78
603
1.35
1.58
3.8
2.4
1.3
1.3
e6/l
0.01
50
308
7
28
2.52
1.45
2.4
1.8
—
—
—
0
0
17
95
1.82
1.45
3.1
2.3
2.0
1.4
mg/l
1.06
17
85
47
339
1.43
1.44
2.3
2.4
69.9
69.8
ml/min/173m2
0.00
18
135
20
119
1.71
1.40
1.0
1.1
—
—
—
0
0
246
2219
1.22
1.39
5.3
4.1
6.5
6.5
mmol/l
0.16
235
2056
7
29
2.43
1.39
1.6
1.2
—
—
—
0
0
433
4166
1.39
1.37
17.5
12.2
16.5
20.0
mg/l
2.03
339
3205
22
136
1.65
1.35
1.6
1.6
0.0
0.1
iu/ml
—
5
17
115
962
1.26
1.31
1.7
1.6
1.0
0.9
mg/l
0.28
93
735
182
1602
1.22
1.29
4.8
3.6
—
—
—
0
0
20
122
1.67
1.29
1.2
1.3
—
—
—
0
0
11
55
2.02
1.28
1.1
1.1
—
—
—
0
0
22
139
1.61
1.25
1.4
1.2
—
—
—
0
0
22
139
1.61
1.25
1.4
1.2
—
—
—
0
0
436
4210
1.37
1.25
17.3
13.2
139.7
139.7
mmol/l
0.29
429
4092
99
820
1.26
1.23
1.5
1.6
50549872.6
30205732.3
pmol/l
0.15
91
682
13
71
1.85
1.20
1.3
1.2
—
—
—
0
0
13
71
1.85
1.20
1.3
1.2
—
—
—
0
0
436
4219
1.35
1.14
17.6
13.2
3.9
3.9
mmol/l
0.36
427
4088
0
36
0.00
1.14
0.0
1.1
—
1.1
—
0
19
52
401
1.33
1.11
28.1
19.2
1.2
1.2
inr
0.09
14
64
451
4391
1.42
1.10
18.7
13.8
72.0
68.2
umol/l
1.18
451
4391
5
21
2.40
1.09
1.0
1.3
127.7
30.7
ug/l
—
5
21
5
21
2.40
1.09
1.2
1.4
5.3
5.4
mmol/l
—
5
21
5
21
2.40
1.09
1.0
1.2
—
—
—
0
0
7
32
2.20
1.08
2.7
1.4
—
—
—
0
0
7
32
2.20
1.08
2.4
1.7
—
—
—
0
0
7
32
2.20
1.08
2.7
1.4
—
—
—
0
0
7
32
2.20
1.08
2.7
1.4
—
—
—
0
0
7
33
2.14
1.06
1.0
1.0
—
—
—
0
0
26
179
1.48
1.05
1.7
2.3
40.0
39.5
u/l
0.04
21
162
119
1024
1.22
1.05
4.2
2.8
0.3
0.4
e6/l
0.30
90
753
66
532
1.28
1.03
4.2
2.1
2.3
2.4
g/l
1.73
61
487
22
148
1.51
1.00
3.3
2.1
0.6
0.7
%
0.97
22
143
19
124
1.55
0.98
1.3
1.2
—
—
—
0
0
0
31
0.00
0.96
0.0
1.2
—
—
—
0
0
452
4414
1.39
0.95
13.3
9.8
23.0
23.5
u/l
0.37
437
4263
34
254
1.36
0.91
1.1
1.0
—
—
—
0
0
11
63
1.76
0.90
1.1
1.0
—
—
—
0
0
10
56
1.80
0.88
1.7
1.3
—
—
—
0
0
22
153
1.46
0.87
3.3
2.1
1.4
1.1
%
0.34
22
153
11
64
1.74
0.87
2.5
1.9
—
—
—
0
0
69
573
1.24
0.86
4.2
2.2
12.9
13.3
umol/l
0.21
63
521
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
12
72
1.68
0.86
2.5
2.7
0.2
0.4
u/ml
—
6
39
24
171
1.42
0.85
1.3
1.3
213.3
246.0
miu/ml
0.18
15
87
6
31
1.95
0.84
1.2
1.4
—
—
—
0
0
10
57
1.77
0.84
1.7
1.3
—
—
—
0
0
10
57
1.77
0.84
1.7
1.3
—
—
—
0
0
14
90
1.57
0.79
3.4
2.4
—
—
—
0
0
59
487
1.24
0.79
4.3
2.2
24.5
22.3
%
0.64
52
411
0
26
0.00
0.78
0.0
1.5
—
—
—
0
0
226
2099
1.14
0.76
8.1
5.5
9.2
9.6
umol/l
0.42
218
1975
10
59
1.71
0.76
1.7
1.3
—
—
—
0
0
10
59
1.71
0.76
1.7
1.3
—
—
—
0
0
10
59
1.71
0.76
1.7
1.3
—
—
—
0
0
34
263
1.31
0.75
2.6
2.4
2.3
4.7
ug/l
2.38
26
235
66
555
1.22
0.75
4.4
2.5
3.1
4.8
e6/l
0.95
38
264
5
24
2.09
0.74
1.0
1.2
34.0
29.5
nmol/l
—
5
18
34
265
1.30
0.72
2.3
1.4
—
—
—
0
0
11
68
1.63
0.72
5.0
3.3
40.9
41.5
u/ml
0.01
11
68
416
4046
1.21
0.71
4.6
4.2
5.7
5.7
mmol/l
0.22
385
3722
7
41
1.72
0.70
1.1
1.0
1.8
1.5
g/l
—
7
36
11
69
1.61
0.69
2.0
1.2
—
—
—
0
0
5
27
1.86
0.68
1.2
1.1
—
—
—
0
0
98
866
1.17
0.65
1.4
1.3
6.7
12.4
u/ml
0.56
36
341
138
1254
1.14
0.63
3.9
2.3
54.3
55.0
u/l
0.11
132
1160
468
4621
1.44
0.63
24.8
18.4
131.6
132.5
g/l
0.79
462
4557
5
30
1.67
0.61
1.4
1.4
2.8
1.9
mmol/l
—
5
30
47
391
1.22
0.61
2.4
2.1
351.6
369.4
nmol/l
0.24
42
368
0
20
0.00
0.60
0.0
1.0
—
—
—
0
0
55
467
1.20
0.59
1.7
1.6
1.4
1.3
%
0.47
50
415
430
4209
1.20
0.58
5.0
4.6
2.9
2.9
mmol/l
0.34
401
3896
0
23
0.00
0.58
0.0
1.5
—
—
—
0
0
0
23
0.00
0.58
0.0
1.5
—
—
—
0
0
13
90
1.46
0.56
1.7
1.3
—
—
—
0
0
14
99
1.43
0.54
1.4
1.4
—
—
—
0
0
10
66
1.53
0.53
1.2
1.2
1.4
2.0
u/ml
—
5
21
214
2017
1.11
0.52
3.4
2.8
97.6
80.5
ug/l
0.84
203
1869
9
64
1.41
0.51
2.2
1.6
—
—
—
0
0
23
180
1.29
0.50
3.5
3.3
1.9
1.7
mmol/l
0.12
16
140
404
3946
1.15
0.50
13.5
11.1
83.1
83.8
ml/min/173m2
0.26
336
3197
15
110
1.38
0.49
1.5
1.3
—
—
—
0
0
25
199
1.27
0.49
1.7
1.9
1970.4
3470.2
u/l
—
8
82
96
868
1.13
0.48
1.3
1.3
23.1
32.3
iu/ml
0.63
32
291
33
273
1.22
0.47
3.2
2.8
68.8
67.8
g/l
0.31
28
253
16
120
1.34
0.46
1.6
1.3
268.0
303.7
ug/g
—
10
64
100
910
1.12
0.46
1.6
1.5
—
—
—
0
0
5
31
1.62
0.43
1.0
1.1
274.2
298.5
mg/l
—
5
26
5
31
1.62
0.43
3.0
1.3
1.3
1.5
nmol/l
—
5
25
10
70
1.44
0.42
1.3
1.2
—
—
—
0
0
5
33
1.52
0.41
3.2
3.9
—
—
—
0
0
0
15
0.00
0.41
0.0
6.5
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
362
3527
1.11
0.41
4.8
4.5
14.5
14.6
pmol/l
0.03
337
3251
0
17
0.00
0.40
0.0
1.0
—
110.6
—
0
9
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
0
17
0.00
0.40
0.0
1.0
—
131.7
—
0
17
0
17
0.00
0.40
0.0
1.0
—
101.7
—
0
9
5
34
1.48
0.40
1.4
1.8
—
—
—
0
0
0
19
0.00
0.39
0.0
1.2
—
8.7
—
0
19
41
355
1.17
0.38
3.8
2.1
35.4
31.3
u/l
0.47
34
294
386
3781
1.10
0.36
5.5
5.1
38.8
38.7
mmol/mol
0.04
359
3516
12
90
1.34
0.36
2.0
1.6
—
—
—
0
0
421
4144
1.13
0.35
4.6
4.1
4.8
4.9
mmol/l
0.52
396
3862
43
378
1.15
0.34
3.2
3.2
—
—
—
0
0
12
91
1.33
0.34
4.8
4.2
37.9
40.3
mg/l
0.07
12
75
12
91
1.33
0.34
4.8
4.2
22.2
22.7
mg/l
0.04
12
73
23
191
1.21
0.34
1.7
1.9
2.5
2.3
mg/l
0.05
15
134
6
46
1.31
0.33
1.5
1.6
—
—
—
0
0
409
4024
1.11
0.32
5.6
5.3
1.8
2.1
mu/l
0.62
382
3735
13
164
0.79
0.31
1.3
1.7
261.7
315.5
mu/l
0.69
13
144
120
1130
1.08
0.29
1.8
1.6
1.3
1.4
mmol/l
0.21
101
965
7
56
1.25
0.29
1.6
1.6
—
—
—
0
0
297
2894
1.07
0.27
3.1
3.3
—
—
—
0
0
8
66
1.22
0.27
1.6
1.6
—
—
—
0
0
289
2816
1.07
0.26
3.6
2.8
57.5
42.9
u/l
0.72
273
2645
19
224
0.84
0.26
1.2
1.5
—
—
—
0
0
142
1355
1.07
0.25
4.9
3.0
32.3
28.3
u/l
0.77
137
1296
6
82
0.73
0.24
1.3
1.8
—
—
—
0
0
391
3854
1.08
0.23
16.1
13.0
39.5
39.3
%
0.13
287
2914
7
91
0.77
0.22
2.4
1.5
—
—
—
0
0
71
663
1.08
0.22
3.8
3.6
191.3
269.1
ng/l
0.19
50
463
16
135
1.19
0.21
4.4
2.0
—
—
—
0
0
25
221
1.14
0.20
2.1
1.5
—
—
—
0
0
38
416
0.91
0.20
2.1
1.6
—
—
—
0
0
12
142
0.84
0.17
1.3
1.5
—
—
—
0
0
7
63
1.11
0.17
1.6
1.2
—
—
—
0
0
12
101
1.19
0.16
1.6
1.4
—
—
—
0
0
8
98
0.81
0.14
1.1
1.5
—
—
—
0
0
17
151
1.13
0.13
2.7
1.9
—
—
—
0
0
10
117
0.85
0.13
1.4
1.3
1387.4
429.4
mg/l
—
10
107
400
3967
1.05
0.12
4.1
3.7
1.3
1.2
mmol/l
1.17
367
3657
10
85
1.18
0.12
2.2
1.6
—
—
—
0
0
12
137
0.87
0.12
1.3
1.4
—
—
—
0
0
12
137
0.87
0.12
1.3
1.4
—
—
—
0
0
12
137
0.87
0.12
1.3
1.4
—
—
—
0
0
12
137
0.87
0.12
1.3
1.4
—
—
—
0
0
5
47
1.06
0.09
1.8
1.7
—
—
—
0
0
6
54
1.11
0.09
1.7
1.6
—
—
—
0
0
6
55
1.09
0.09
1.0
1.2
—
—
—
0
0
5
61
0.82
0.08
3.8
6.3
274.2
396.2
umol/l
—
5
54
7
65
1.08
0.08
1.3
1.3
—
—
—
0
0
415
4129
1.04
0.07
4.5
4.1
1.6
1.6
mmol/l
1.02
386
3830
16
148
1.08
0.06
4.4
3.3
43.6
45.0
%
0.08
16
148
40
393
1.02
0.01
3.9
3.8
2.9
9.8
ug/l
2.72
32
317
15
146
1.03
0.00
1.3
1.5
—
—
—
0
0
53
525
1.01
0.00
2.6
1.7
29.3
29.3
s
0.04
53
510
15
152
0.99
0.00
1.2
1.5
—
—
—
0
0
16
158
1.01
0.00
1.9
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
2.6
—
1.2
—
0
7
0
6
0.00
0.00
0.0
2.2
—
—
—
0
0
(3002348) Coagulation factor XII activity actual/normal in Platelet poor plasma by Coagulation assay
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
39
390
1.00
0.00
1.2
1.2
98.0
167.0
iu/ml
0.93
15
179
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
6
63
0.95
0.00
1.7
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
4.9
—
0
5
0
8
0.00
0.00
0.0
1.0
—
117.5
—
0
8
Mortality – FinRegistry
↥Association
Association between endpoint N14_VAGINAL_HSIL and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| N14_VAGINAL_HSIL | 1.265 [1.08, 1.48] | 0.003 |
| Birth year | 0.998 [0.99, 1.01] | 0.566 |
During the follow-up period (1.1.1998 — 31.12.2019), 266 out of 2226 females with N14_VAGINAL_HSIL died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have N14_VAGINAL_HSIL.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.089% | No data |
| 5 | 0.774% | No data |
| 10 | 1.998% | No data |
| 15 | 3.721% | No data |
| 20 | 6.738% | No data |
Relationships between endpoints
↥Index endpoint: N14_VAGINAL_HSIL – HSIL lesion of the vagina
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data