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Frostbite

ST19_FROSTBITE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 T33-T35
  • Cause of death: ICD-10 T33-T35

2 out of 7 registries used, show all original rules.

419

4. Check minimum number of events

None

419

5. Include endpoints

419

6. Filter based on genotype QC (FinnGen only)

398

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
S|T
Name in latin
Congelatio

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 398 139 259
Unadjusted period prevalence (%) 0.09 0.05 0.12
Median age at first event (years) 49.07 45.93 50.75

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
419
Matched controls
4190
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
X31
ICD-10 Finland
Exposure to excessive natural cold
525.7
174.3
162
5
T33.8
ICD-10 Finland
Superficial frostbite of ankle and foot
1205.1
100.4
94
*
T33.5
ICD-10 Finland
Superficial frostbite of wrist and hand
+∞
88.8
82
*
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
7.0
56.3
101
183
T34.8
ICD-10 Finland
Frostbite with tissue necrosis of ankle and foot
+∞
47.8
45
*
T33.9
ICD-10 Finland
Superficial frostbite of other and unspecified sites
+∞
44.6
42
*
T68
ICD-10 Finland
Hypothermia
60.0
41.5
48
9
T36
ICD-10 Finland
Poisoning by systemic antibiotics
8.0
40.5
59
84
X59
ICD-10 Finland
Exposure to unspecified factor
4.1
40.4
156
529
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
9.1
40.2
52
64
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
7.5
39.9
62
95
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
9.3
39.4
50
60
T34.5
ICD-10 Finland
Frostbite with tissue necrosis of wrist and hand
+∞
39.2
37
*
T35.5
ICD-10 Finland
Unspecified frostbite of lower limb
+∞
36.0
34
*
T35.4
ICD-10 Finland
Unspecified frostbite of upper limb
+∞
34.9
33
*
N05AA02
ATC
levomepromazine; systemic
7.5
34.8
53
79
N07BB01
ATC
disulfiram; oral
6.4
33.2
60
107
X58
ICD-10 Finland
Exposure to other specified factors
3.9
31.5
120
395
N05AH04
ATC
quetiapine; oral
3.6
30.2
130
463
N05AH03
ATC
olanzapine; systemic
5.0
28.6
69
160
T33.4
ICD-10 Finland
Superficial frostbite of arm
+∞
28.5
27
*
AA1AD
NOMESCO Finland
CT of head and brain
3.1
26.2
154
657
F29
ICD-10 Finland
Unspecified nonorganic psychosis
5.8
25.8
50
95
SPAT1148
SPAT
Treatment of chronic ulcer or burn
3.9
25.8
90
276
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
8.7
25.1
33
41
T33.0
ICD-10 Finland
Superficial frostbite of head
+∞
24.2
23
*
N05BA04
ATC
oxazepam; oral
2.8
20.8
139
624
R56.8
ICD-10 Finland
Other and unspecified convulsions
4.8
20.7
50
115
F10.25
ICD-10 Finland
Alcohol dependence continuous use
8.3
20.7
28
36
F10.20
ICD-10 Finland
Alcohol dependence currently independent
7.6
20.6
30
42
P15
ICPC
Chronic alcohol abuse
5.6
20.3
40
77
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
4.1
19.8
59
160
N05CD07
ATC
temazepam; oral
3.6
19.2
73
235
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.6
19.0
163
824
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
6.6
18.7
31
50
NDQ20
NOMESCO Finland
Amputation of finger
55.1
18.1
21
*
F10.24
ICD-10 Finland
Alcohol depence active use
8.0
18.0
25
33
W93
ICD-10 Finland
Exposure to excessive cold of man-made origin
+∞
17.8
17
*
N05AF03
ATC
chlorprothixene; systemic
7.1
17.6
27
40
S06.0
ICD-10 Finland
Concussion
3.3
17.6
77
270
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.0
17.4
94
372
N05AX08
ATC
risperidone; systemic
3.6
17.2
63
197
A46
ICD-10 Finland
Erysipelas
3.0
16.9
86
329
NHQ40
NOMESCO Finland
Amputation of toe
13.5
16.9
29
23
QCB10
NOMESCO Finland
Major dressing of wound of skin of upper limb
7.0
16.8
26
39
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.3
16.7
70
239
N06AX11
ATC
mirtazapine; oral
2.4
16.4
168
909
S97
ICPC
Chronic ulcer skin
4.3
16.3
45
115
S01.0
ICD-10 Finland
Open wound of scalp
3.7
15.8
53
156
T33.7
ICD-10 Finland
Superficial frostbite of knee and lower leg
+∞
15.7
15
*
G72.8
ICD-10 Finland
Other specified myopathies
7.0
15.5
24
36
W00
ICD-10 Finland
Fall on same level involving ice and snow
3.2
15.3
69
245
SPAT1254
SPAT
Administration of medicine
2.9
15.2
82
323
F32.9
ICD-10 Finland
Depressive episode, unspecified
3.0
15.2
79
305
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.8
15.1
89
368
F10.49
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without information about seizures
37.5
14.6
18
5
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.4
14.5
127
635
F05.9
ICD-10 Finland
Delirium, unspecified
12.6
14.3
25
21
ZZA00
NOMESCO Finland
Split skin graft
5.3
14.0
29
58
L28
ICPC
Limited function/disability (L)
2.9
13.9
76
301
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
3.7
13.9
47
139
F10.40
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without seizures
15.4
13.7
22
15
T34.4
ICD-10 Finland
Frostbite with tissue necrosis of arm
+∞
13.6
13
*
T35.0
ICD-10 Finland
Superficial frostbite involving multiple body regions
+∞
13.6
13
*
S19
ICPC
Skin injury other
4.8
13.0
30
66
F10.39
ICD-10 Finland
Withdrawal symptoms caused by alcohol UNS
11.0
12.9
24
23
T34.9
ICD-10 Finland
Frostbite with tissue necrosis of other and unspecified sites
+∞
12.6
12
*
N05CF01
ATC
zopiclone; oral
2.2
12.4
148
836
NA1AD
NOMESCO Finland
Cervical spine CT examination
4.0
12.4
37
100
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.8
11.8
63
245
N05BA01
ATC
diazepam; systemic, rectal
2.7
11.8
69
282
N05AD01
ATC
haloperidol; systemic
4.8
11.3
26
57
F60.31
ICD-10 Finland
Emotionally unstable personality disorder, borderline condition
13.2
11.2
19
15
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
3.5
11.0
40
124
SPAT1149
SPAT
Suture or treatment of traumatic wound
2.6
11.0
68
286
N05AB03
ATC
perphenazine; systemic, rectal
4.5
10.9
27
63
QDG20
NOMESCO Finland
Operation for chronic ulcer or fistula of skin of lower limb
16.0
10.9
17
11
SPAT1301
SPAT
No procedures
2.1
10.9
138
792
F20.9
ICD-10 Finland
Schizophrenia, unspecified
5.1
10.9
23
47
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.8
10.8
58
226
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
8.3
10.7
23
29
N02AA05
ATC
oxycodone; systemic
2.4
10.7
81
375
N03AE01
ATC
clonazepam; systemic
3.6
10.5
36
107
F10.26
ICD-10 Finland
Alcohol dependence periodic alcoholism
8.0
10.5
23
30
S18
ICPC
Laceration/cut
2.0
10.5
193
1263
N06AB04
ATC
citalopram; systemic
2.3
10.4
91
448
X39
ICD-10 Finland
Exposure to other and unspecified forces of nature
33.4
10.4
13
*
R41.0
ICD-10 Finland
Disorientation, unspecified
4.9
10.4
23
49
N03AX16
ATC
[U] pregabalin
2.2
10.3
103
536
N06CA01
ATC
amitriptyline and psycholeptics; systemic
3.1
10.3
45
156
N03AG01
ATC
valproic acid; systemic, rectal
3.4
10.3
39
124
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
3.0
10.3
49
179
P99
ICPC
Psychological disorders other
4.8
10.1
23
50
F10.09
ICD-10 Finland
Alcohol intoxication UNS
4.6
9.9
24
55
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.4
9.8
78
368
ZXD05
NOMESCO Finland
Urgent procedure
2.0
9.5
132
776
B18.2
ICD-10 Finland
Chronic viral hepatitis C
7.8
9.5
21
28
P19
ICPC
Drug abuse
12.7
9.4
16
13
SPAT1263
SPAT
Sampling
1.9
9.4
179
1174
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.9
9.3
47
177
N02BF02
ATC
pregabalin; oral
3.4
9.3
34
106
N05AF05
ATC
zuclopenthixol; systemic
16.0
9.1
14
9
N04AA02
ATC
biperiden; systemic
8.2
8.9
19
24
Y94.8
ICD-10 Finland
Other leisure activity accident
4.8
8.9
20
43
3039X
ICD-9 Finland
Alcohol dependence syndrome, Other and unspecified alcohol dependence
9.8
8.9
17
18
F10.30
ICD-10 Finland
Withdrawal symptoms caused by alcohol uncomplicated
9.8
8.9
17
18
EBA00
NOMESCO Finland
Extraction of tooth
1.9
8.8
168
1095
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
4.4
8.8
22
52
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
4.9
8.7
19
40
F19.1
ICD-10 Finland
Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances, harmful use
11.9
8.6
15
13
W19
ICD-10 Finland
Unspecified fall
2.6
8.5
52
216
S14
ICPC
Burn/scald
3.9
8.5
25
67
WX882
NOMESCO Finland
High dependency care
5.0
8.4
18
37
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
3.5
8.4
29
87
T33.6
ICD-10 Finland
Superficial frostbite of hip and thigh
+∞
8.4
8
*
F19.00
ICD-10 Finland
Intoxication caused by several drugs in combination or by other psychoactive substances uncomplicated
+∞
8.4
8
*
N06AB03
ATC
fluoxetine; oral
2.5
8.3
57
251
T74.1
ICD-10 Finland
Physical abuse
4.7
8.2
19
42
N07BA03
ATC
varenicline; oral
3.4
8.1
30
94
N05AA01
ATC
chlorpromazine; systemic, rectal
10.3
8.1
15
15
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
3.5
8.1
28
84
Z72.2
ICD-10 Finland
Drug use
22.5
8.1
11
5
F10.9
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Unspecified mental and behavioural disorder
9.7
7.8
15
16
L17
ICPC
Foot/toe symptom/complaint
1.9
7.8
118
710
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.5
7.7
50
214
F99
ICD-10 Finland
Mental disorder, not otherwise specified
4.7
7.7
18
40
SPAT1104
SPAT
Monitoring of emergency patient
3.1
7.7
32
108
P20
ICPC
Memory disturbance
2.5
7.6
51
222
F10.31
ICD-10 Finland
Withdrawal symptoms caused by alcohol with seizures
10.3
7.6
14
14
V03AA01, ,
ATC
6.7
7.5
18
28
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.6
7.5
46
192
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
3.0
7.4
33
116
SPAT1234
SPAT
Support of social functional capacity
3.4
7.4
27
84
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
3.2
7.4
30
100
QCB05
NOMESCO Finland
Revision of wound of skin of upper limb
9.6
7.3
14
15
T34.0
ICD-10 Finland
Frostbite with tissue necrosis of head
+∞
7.3
7
*
T34.7
ICD-10 Finland
Frostbite with tissue necrosis of knee and lower leg
+∞
7.3
7
*
T35.3
ICD-10 Finland
Unspecified frostbite of thorax, abdomen, lower back and pelvis
+∞
7.3
7
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.7
7.3
41
164
N03AX12
ATC
[U] gabapentin; oral
2.1
7.2
71
364
N06AX16
ATC
venlafaxine; oral
2.2
7.2
62
302
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.7
7.2
39
153
F10.2
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Dependence syndrome
8.1
7.2
15
19
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.2
7.1
63
310
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.8
7.1
36
136
F10.21
ICD-10 Finland
Alcohol dependence currently abstinent, but staying in restrictive environment
7.2
7.1
16
23
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
3.8
7.0
21
57
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.7
7.0
176
1230
3018X
ICD-9 Finland
Personality disorders, Other personality disorders[MUU TAI SEKAMUOTOINEN PERSOONALLISUUSHÄIRIÖ]
14.1
6.9
11
8
R33
ICD-10 Finland
Retention of urine
2.6
6.9
40
162
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.3
6.9
55
259
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
3.5
6.8
23
68
S06.5
ICD-10 Finland
Traumatic subdural haemorrhage
4.0
6.8
19
49
TQW10
NOMESCO Finland
Exchange of bandage for burn
40.7
6.8
8
*
QDD00
NOMESCO Finland
Dressing of major burn of lower limb
17.0
6.8
10
6
P29
ICPC
Psychological sympt/compl other
2.5
6.7
43
183
S00.0
ICD-10 Finland
Superficial injury of scalp
5.7
6.7
18
33
B01AB05
ATC
enoxaparin; parenteral
1.8
6.7
116
725
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.7
6.6
35
135
N02AX02
ATC
tramadol; systemic, rectal
1.7
6.6
169
1181
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
2.2
6.6
55
264
F60.9
ICD-10 Finland
Personality disorder, unspecified
7.0
6.6
15
22
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.8
6.6
125
802
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.6
6.5
21
60
IBZ01
NOMESCO Finland
Profession-specific psychiatric evaluation
4.0
6.5
18
46
SPAT1240
SPAT
Therapeutic discussion
2.3
6.5
53
252
Z2446
NOMESCO Finland
Social worker
2.7
6.5
36
143
S82.6
ICD-10 Finland
Fracture of lateral malleolus
2.9
6.5
30
108
N06AB10
ATC
escitalopram; oral
1.9
6.5
91
531
R42
ICD-10 Finland
Dizziness and giddiness
1.9
6.4
85
485
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
2.4
6.4
43
187
S22.3
ICD-10 Finland
Fracture of rib
2.5
6.4
42
181
N02BF01
ATC
gabapentin; oral
2.7
6.4
34
132
EBA15
NOMESCO Finland
Extraction of multiple teeth
3.6
6.4
21
61
T51.0
ICD-10 Finland
Toxic effect: Ethanol
9.5
6.3
12
13
T35.7
ICD-10 Finland
Unspecified frostbite of unspecified site
+∞
6.3
6
*
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.9
6.3
30
110
N05BE01
ATC
buspirone; oral
3.6
6.2
20
57
C03CA01
ATC
furosemide; systemic
1.8
6.2
109
681
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.4
6.1
45
204
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.7
6.1
34
135
E950A
ICD-9 Finland
Suicide and self-inflicted poisoning by solid or liquid substances
8.8
6.1
12
14
N17.9
ICD-10 Finland
Acute renal failure, unspecified
3.5
6.1
21
63
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
5.3
6.1
17
33
J01FF01
ATC
clindamycin; systemic
1.8
6.1
112
710
N03AX09
ATC
lamotrigine; oral
3.0
6.1
27
95
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
2.8
6.0
31
118
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
4.0
6.0
17
44

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
28
38
7.82
19.74
2.0
1.4
1.95
1.40
promille
0.66
20
27
175
916
2.56
18.96
3.0
2.1
642.30
301.38
u/l
0.99
170
868
96
384
2.95
17.48
2.2
1.6
—
—
—
0
0
151
838
2.25
13.40
5.7
4.4
—
—
—
0
0
38
102
4.00
12.85
3.9
2.6
—
—
—
0
0
210
1360
2.09
12.28
13.2
13.2
1.27
1.26
inr
0.07
63
415
214
1404
2.07
12.00
9.5
7.3
1.20
1.21
mmol/l
1.10
188
1209
185
1159
2.07
11.67
4.5
3.5
246.31
64.50
ng/l
0.39
133
770
99
491
2.33
11.22
1.9
1.6
1236.42
1159.83
nmol/l
0.33
78
374
56
213
2.88
10.94
3.4
2.0
—
—
—
0
0
161
986
2.03
10.57
3.6
2.6
60.52
62.76
u/l
0.14
151
923
75
338
2.48
10.47
9.2
10.0
1.22
1.11
mmol/l
0.07
55
271
195
1288
1.96
10.23
8.1
6.4
1.20
1.21
mmol/l
1.27
187
1180
82
390
2.37
10.16
6.6
6.3
1.08
1.01
mmol/l
1.24
77
365
50
186
2.92
10.15
3.8
2.0
—
—
—
0
0
57
228
2.74
10.12
3.6
2.0
—
—
—
0
0
232
1631
1.95
10.06
5.8
6.3
11.23
11.85
umol/l
0.38
221
1547
45
160
3.03
9.89
4.8
2.8
—
—
—
0
0
57
231
2.70
9.86
3.6
2.0
—
—
—
0
0
57
231
2.70
9.86
3.6
2.0
—
—
—
0
0
188
1257
1.90
9.25
6.2
5.2
34.61
35.89
g/l
1.88
172
1184
19
23
8.60
9.16
2.3
2.2
—
—
—
0
0
306
2419
1.98
8.76
7.4
7.3
74.56
77.04
u/l
0.78
296
2284
51
208
2.65
8.70
7.1
6.7
—
—
—
0
0
54
227
2.58
8.67
3.4
1.8
—
—
—
0
0
247
1832
1.85
8.49
7.5
5.1
6.64
6.69
mmol/l
0.12
234
1695
59
263
2.45
8.37
4.4
3.9
2.50
1.72
mmol/l
0.85
43
209
14
15
9.61
7.33
2.1
2.5
116.75
97.25
umol/l
—
8
8
163
1123
1.74
6.72
3.9
3.4
36.13
34.73
u/l
0.11
155
1076
96
573
1.88
6.34
1.6
1.7
105128635.17
8048719.00
pmol/l
0.44
78
497
125
811
1.77
6.29
3.8
2.9
—
—
—
0
0
190
1412
1.63
5.63
3.1
2.6
—
—
—
0
0
50
252
2.12
5.30
2.2
2.2
5.44
9.42
ug/l
1.28
44
226
283
2356
1.62
4.99
4.9
3.2
51.76
49.24
u/l
0.18
273
2235
76
457
1.81
4.83
3.0
2.1
—
—
—
0
0
134
946
1.61
4.71
2.6
2.3
—
—
—
0
0
109
737
1.65
4.54
2.2
1.9
2.99
2.95
mg/l
0.07
97
641
42
212
2.09
4.45
4.4
3.0
7.40
7.42
ph
—
7
27
42
213
2.08
4.39
4.4
3.0
5.38
5.09
kpa
0.82
37
206
105
711
1.64
4.33
5.3
3.3
1.02
1.02
kg/l
0.12
20
100
194
1518
1.52
4.23
5.6
6.3
—
—
—
0
0
117
819
1.59
4.20
5.8
3.5
0.00
0.00
estimate
0.50
38
291
259
2156
1.53
4.19
5.1
3.9
—
—
—
0
0
27
116
2.42
4.18
7.2
4.3
—
—
—
0
0
32
150
2.23
4.08
4.2
3.1
—
—
—
0
0
194
1529
1.50
4.02
5.6
4.5
0.00
0.00
estimate
-0.00
42
307
14
37
3.88
3.93
17.0
21.2
66618.71
1323.27
nmol/l
0.47
14
37
51
289
1.87
3.91
2.8
2.3
0.21
0.22
g/l
0.49
45
265
45
249
1.90
3.71
9.2
9.3
—
—
—
0
0
128
938
1.52
3.70
2.9
3.3
2.33
2.35
mmol/l
0.56
110
833
194
1553
1.46
3.60
4.6
3.3
0.00
0.00
estimate
-0.00
39
288
118
860
1.52
3.47
4.5
3.7
—
—
—
0
0
62
387
1.71
3.45
9.1
7.5
104.52
104.18
mmol/l
0.22
62
387
127
941
1.50
3.45
3.3
3.0
56.08
121.43
e6/l
0.43
99
728
10
22
4.63
3.45
1.1
1.7
91.70
74.32
umol/l
—
10
22
92
643
1.55
3.26
2.8
2.4
4.39
4.34
e6/l
0.02
84
570
160
1254
1.45
3.23
3.8
3.0
6.05
5.85
ph
—
10
103
7
11
6.45
3.19
5.3
2.7
—
—
—
0
0
189
1536
1.42
3.10
4.7
3.3
0.00
0.00
estimate
0.50
38
319
222
1858
1.41
3.07
9.2
9.1
4.56
4.13
e9/l
1.41
191
1632
94
669
1.52
3.06
1.4
1.5
19.41
20.65
nmol/l
0.33
82
575
32
169
1.97
3.04
14.5
13.2
—
—
—
0
0
81
560
1.55
3.00
4.2
3.5
79.55
301.37
ng/l
1.79
60
427
17
69
2.53
3.00
3.1
2.8
—
—
—
0
0
105
769
1.49
2.97
5.9
6.4
—
—
—
0
0
145
1142
1.41
2.77
2.2
1.9
90.34
94.72
pmol/l
0.61
87
599
27
139
2.01
2.77
3.0
2.5
0.71
0.65
%
0.44
27
139
185
1521
1.39
2.74
6.1
5.9
2.86
2.83
%
0.07
175
1445
38
221
1.79
2.72
3.7
3.2
—
—
—
0
0
200
1668
1.38
2.71
6.0
5.8
1.85
1.91
e9/l
0.29
176
1509
194
1611
1.38
2.69
6.0
5.7
0.62
0.59
e9/l
1.03
165
1423
139
1093
1.41
2.67
3.9
3.5
261.62
118.69
e6/l
0.45
101
773
55
812
0.63
2.65
2.3
2.8
0.65
0.77
ug/l
0.69
33
490
185
1529
1.38
2.63
7.0
6.3
8.66
8.69
%
0.04
174
1458
111
842
1.43
2.60
4.8
3.9
7.40
7.40
ph
0.06
20
155
92
674
1.47
2.58
4.5
3.2
—
—
—
0
0
190
1581
1.37
2.57
6.2
6.0
26.51
27.81
%
0.95
179
1507
124
962
1.41
2.56
3.7
3.2
7.41
8.39
mmol/l
1.28
112
824
108
819
1.43
2.52
3.2
2.9
—
—
—
0
0
193
1614
1.36
2.52
6.0
5.7
0.04
0.04
e9/l
0.24
165
1430
86
625
1.47
2.51
3.2
2.7
495.55
569.84
mosm/kgh2o
2.33
76
535
93
687
1.45
2.50
1.9
1.8
1.14
1.30
mg/l
0.23
67
513
10
251
0.38
2.47
1.0
1.4
—
—
—
0
0
39
236
1.72
2.46
3.1
5.3
0.00
0.14
%
2.17
11
77
198
1667
1.36
2.45
6.1
6.0
0.21
0.19
e9/l
0.36
170
1492
97
1257
0.70
2.40
2.5
2.6
—
—
—
0
0
33
192
1.78
2.38
3.4
2.8
160.36
170.80
ng/l
0.04
28
166
41
256
1.67
2.31
3.0
5.0
0.96
0.96
%
0.00
13
99
25
135
1.91
2.27
2.6
2.2
—
—
—
0
0
0
60
0.00
2.26
0.0
1.2
—
15.15
—
0
52
55
374
1.54
2.20
2.3
3.0
7.80
9.32
umol/l
0.39
50
330
8
24
3.38
2.19
9.6
8.5
0.62
0.59
mmol/l
—
8
24
185
1562
1.33
2.18
6.3
5.7
58.26
57.18
%
0.61
174
1492
14
61
2.34
2.17
4.0
2.4
—
—
—
0
0
176
1476
1.33
2.17
5.6
6.0
0.65
0.66
%
0.10
165
1402
10
36
2.82
2.15
1.9
2.2
—
—
—
0
0
13
55
2.41
2.14
1.8
1.4
—
—
—
0
0
37
230
1.67
2.14
3.2
5.3
0.00
0.18
%
—
10
71
30
176
1.76
2.12
2.5
2.5
0.28
0.14
e6/l
0.36
30
168
261
2321
1.33
2.11
3.9
3.4
14.71
14.75
pmol/l
0.10
235
2097
42
273
1.60
2.05
3.3
3.5
—
—
—
0
0
106
834
1.36
1.97
3.3
3.0
0.20
0.47
e6/l
1.55
81
636
352
3293
1.43
1.95
24.9
14.9
139.40
139.65
mmol/l
1.03
346
3203
353
3305
1.43
1.94
24.8
15.0
4.00
3.98
mmol/l
0.79
346
3212
11
46
2.43
1.86
1.3
1.4
—
—
—
0
0
26
421
0.59
1.84
1.2
1.3
—
—
—
0
0
6
17
3.56
1.84
1.8
2.2
9.17
10.18
mmol/l
—
6
17
14
66
2.16
1.84
3.9
3.1
4.85
5.04
kpa
0.76
14
66
14
66
2.16
1.84
3.9
3.1
8.09
8.65
kpa
0.64
14
66
14
66
2.16
1.84
3.9
3.1
1.83
2.34
mmol/l
—
9
44
36
233
1.60
1.80
3.0
4.9
0.30
0.45
%
—
10
82
66
487
1.42
1.79
2.1
3.1
2.45
2.44
mmol/l
0.28
52
423
13
61
2.17
1.73
2.4
3.2
—
—
—
0
0
351
3303
1.39
1.69
22.6
13.0
24.53
23.88
mg/l
0.15
305
2577
43
295
1.51
1.68
1.9
1.5
—
—
—
0
0
7
25
2.83
1.65
1.1
1.8
9.87
12.66
%
—
7
25
165
1412
1.28
1.65
12.6
9.3
0.00
0.00
e9/l
0.55
141
1159
5
14
3.60
1.62
3.2
2.5
38780.00
34478.93
ug/l
—
5
14
61
459
1.39
1.49
2.7
2.3
12.02
13.65
umol/l
0.87
54
429
57
424
1.40
1.49
2.7
2.3
2.18
2.32
g/l
1.05
50
391
35
237
1.52
1.47
2.3
2.7
87.31
73.84
e9/l
0.76
25
181
62
471
1.37
1.44
2.0
1.6
—
—
—
0
0
31
207
1.54
1.40
5.8
2.5
4.65
7.92
e9/l
0.60
26
176
14
75
1.90
1.36
3.9
3.1
7.40
7.42
ph
0.94
14
69
16
90
1.81
1.35
1.6
1.2
—
—
—
0
0
153
1327
1.24
1.31
3.0
2.5
127.95
143.79
ug/l
0.41
139
1225
9
45
2.02
1.24
1.1
1.1
—
—
—
0
0
12
63
1.93
1.24
3.0
3.1
5.92
4.50
e9/l
0.71
12
63
238
2173
1.22
1.22
4.3
3.6
—
—
—
0
0
252
2316
1.22
1.20
3.9
3.7
10.65
10.61
mm/h
0.01
236
2135
12
64
1.90
1.19
3.4
3.7
64.67
57.69
%
0.91
12
64
30
207
1.48
1.19
4.4
3.9
128.25
82.16
ng/l
1.18
22
192
5
20
2.52
1.15
1.0
1.0
345.80
269.45
ng/l
—
5
11
5
20
2.52
1.15
1.8
5.1
—
—
—
0
0
5
20
2.52
1.15
1.0
1.0
547.40
531.90
ng/l
—
5
10
107
904
1.25
1.15
4.1
2.9
—
—
—
0
0
44
329
1.38
1.15
1.9
2.7
2.28
1.86
%
0.86
38
300
18
113
1.62
1.07
1.3
1.4
127.20
278.49
miu/ml
—
5
50
9
46
1.98
1.04
1.6
1.3
—
—
—
0
0
13
75
1.76
1.04
1.7
1.3
—
—
—
0
0
103
880
1.23
1.00
3.3
3.9
8.97
10.09
mg/mmol
0.14
77
606
364
3506
1.29
0.99
11.9
9.5
28.62
29.51
u/l
0.38
355
3407
123
1395
0.83
0.94
3.4
4.5
1.67
2.30
ug/l
1.08
109
1276
7
37
1.91
0.94
1.4
4.1
—
—
—
0
0
7
37
1.91
0.94
1.4
1.9
33.86
33.89
pg
—
7
37
18
119
1.54
0.89
2.8
2.6
558.96
3499.96
u/l
—
5
50
71
590
1.24
0.89
2.0
1.6
—
—
—
0
0
8
42
1.92
0.89
14.9
1.7
13.38
13.13
%
—
8
42
16
103
1.58
0.88
1.1
1.3
—
3.40
—
0
8
36
274
1.34
0.87
3.6
4.3
—
—
—
0
0
106
921
1.20
0.87
1.3
1.5
—
—
—
0
0
131
1162
1.19
0.86
2.8
2.2
70.36
74.41
nmol/l
0.79
122
1044
6
31
1.95
0.84
4.8
3.1
119.38
20.62
mg/l
—
6
26
100
1144
0.83
0.84
1.9
2.0
—
—
—
0
0
33
252
1.34
0.79
1.2
1.2
—
—
—
0
0
0
25
0.00
0.79
0.0
1.1
—
137651.50
—
0
18
0
28
0.00
0.76
0.0
1.1
—
0.08
—
0
5
30
389
0.75
0.75
1.4
1.4
—
—
—
0
0
58
482
1.24
0.74
3.0
2.8
2.82
1.56
e6/l
0.81
26
272
49
400
1.25
0.73
3.1
2.3
22.67
24.66
%
0.23
35
354
95
831
1.19
0.73
2.9
3.3
57.29
142.31
mg/l
0.55
71
579
16
109
1.49
0.72
1.6
1.8
—
—
—
0
0
46
374
1.26
0.72
1.8
1.5
—
—
—
0
0
7
42
1.68
0.68
1.3
1.2
—
—
—
0
0
5
27
1.86
0.68
1.8
1.1
—
—
—
0
0
26
338
0.75
0.68
1.6
1.7
—
—
—
0
0
5
30
1.67
0.61
1.2
1.7
43.12
38.52
%
—
5
30
13
88
1.49
0.61
1.4
3.1
—
—
—
0
0
11
163
0.67
0.61
1.0
1.1
—
—
—
0
0
25
193
1.31
0.59
5.5
2.4
—
—
—
0
0
7
111
0.62
0.59
7.6
10.3
—
—
—
0
0
11
160
0.68
0.56
2.5
1.6
—
—
—
0
0
10
65
1.55
0.56
1.3
1.3
4.00
145.63
e6/l
—
10
51
92
822
1.15
0.55
1.8
1.7
1.22
1.45
mmol/l
3.12
82
704
6
38
1.59
0.54
3.8
3.2
—
—
—
0
0
299
2889
1.12
0.47
24.2
15.6
14.75
14.73
%
0.02
294
2850
84
755
1.14
0.47
2.4
2.0
—
—
—
0
0
34
405
0.83
0.46
2.4
2.4
232.49
117.61
ug/g
0.48
26
326
356
3481
1.15
0.44
21.9
11.8
—
—
—
0
0
18
139
1.31
0.44
1.3
1.3
—
—
—
0
0
5
32
1.57
0.42
1.4
1.2
—
—
—
0
0
8
57
1.41
0.42
1.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
5
34
1.48
0.40
1.4
1.4
0.34
0.35
g/l
—
5
22
5
34
1.48
0.40
1.4
1.4
2.68
2.63
g/l
—
5
23
5
34
1.48
0.40
1.4
1.4
5.92
6.83
g/l
—
5
23
30
355
0.83
0.39
1.8
1.4
—
—
—
0
0
5
35
1.43
0.39
1.4
1.3
—
—
—
0
0
27
322
0.83
0.38
1.3
1.3
—
—
—
0
0
5
37
1.36
0.37
2.2
2.9
—
—
—
0
0
5
37
1.36
0.37
2.2
2.9
4.32
4.08
mmol/l
—
5
37
5
37
1.36
0.37
2.2
2.9
108.00
105.35
mmol/l
—
5
37
6
42
1.43
0.35
1.2
1.2
—
—
—
0
0
6
42
1.43
0.35
1.2
1.0
0.83
2.05
u/ml
—
6
17
6
86
0.69
0.33
1.0
3.7
24.70
131.87
mg/l
—
6
69
6
46
1.31
0.33
1.2
1.2
—
—
—
0
0
31
357
0.86
0.31
1.5
1.2
—
—
—
0
0
7
52
1.35
0.31
1.0
1.1
—
132.33
—
0
12
7
98
0.71
0.31
1.3
1.1
—
—
—
0
0
16
129
1.25
0.30
2.4
3.4
—
—
—
0
0
10
75
1.34
0.30
1.3
1.2
—
—
—
0
0
34
385
0.87
0.28
2.5
2.3
14.76
14.07
nmol/l
0.19
27
357
5
72
0.69
0.26
1.2
1.1
—
—
—
0
0
42
379
1.12
0.25
1.4
1.3
—
—
—
0
0
60
645
0.92
0.22
1.5
1.4
2.89
2.45
g/l
0.49
36
418
5
42
1.19
0.21
1.4
1.5
1.63
0.34
nmol/l
—
5
33
0
12
0.00
0.21
0.0
1.5
—
29.50
—
0
12
0
12
0.00
0.21
0.0
3.1
—
8.98
—
0
12
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
6
49
1.23
0.20
1.3
1.0
0.32
1.64
u/ml
—
6
26
6
50
1.20
0.20
2.5
2.8
—
—
—
0
0
6
51
1.18
0.19
6.5
2.7
—
—
—
0
0
27
242
1.12
0.18
1.3
1.4
—
—
—
0
0
7
60
1.17
0.18
1.3
2.1
—
—
—
0
0
292
2876
1.05
0.16
4.9
4.1
1.92
1.90
mu/l
0.12
267
2648
10
119
0.84
0.15
1.2
1.2
—
—
—
0
0
9
78
1.16
0.15
3.3
3.8
—
—
—
0
0
7
86
0.81
0.14
1.0
3.7
17.66
30.54
mg/l
—
7
69
22
201
1.10
0.11
1.7
1.3
—
37.22
—
0
13
293
2896
1.04
0.11
5.9
5.3
39.76
39.70
mmol/mol
0.03
271
2714
19
174
1.10
0.09
1.3
2.4
—
—
—
0
0
373
3751
0.95
0.09
31.1
18.6
39.99
41.16
%
2.64
346
3523
6
55
1.09
0.09
1.2
1.1
0.41
3.18
u/ml
—
6
24
51
490
1.05
0.08
1.2
1.3
30.66
31.87
iu/ml
0.03
20
151
74
718
1.04
0.08
1.3
1.2
1.60
1.22
u/ml
0.25
13
190
7
68
1.03
0.08
1.0
1.1
—
—
—
0
0
82
798
1.03
0.07
2.3
2.6
344.06
6348.11
umol/l
2.87
72
698
8
74
1.08
0.07
1.0
1.3
—
2.96
—
0
10
7
81
0.86
0.07
1.0
2.2
36.43
38.95
g/l
—
7
75
14
152
0.92
0.06
1.1
1.0
—
—
—
0
0
10
90
1.11
0.05
1.0
1.2
—
—
—
0
0
41
396
1.04
0.05
1.7
1.8
—
—
—
0
0
322
3203
1.02
0.05
4.2
4.1
4.47
4.61
mmol/l
1.52
299
3003
42
407
1.04
0.04
1.4
1.4
230.00
433.25
titre
1.85
12
77
16
169
0.94
0.03
1.3
1.2
—
—
—
0
0
313
3117
1.02
0.03
4.5
4.1
5.91
5.92
mmol/l
0.02
283
2856
12
128
0.94
0.02
2.5
2.5
—
—
—
0
0
376
3751
1.02
0.02
30.6
18.5
242.69
245.57
e9/l
0.35
365
3663
45
459
0.98
0.02
1.2
1.2
1.21
6.18
u/ml
2.73
16
180
22
228
0.96
0.02
1.1
1.4
—
—
—
0
0
327
3260
1.01
0.02
4.5
4.5
2.66
2.78
mmol/l
1.46
304
3027
308
3086
0.99
0.00
3.7
3.7
1.32
1.32
mmol/l
0.05
281
2868
376
3758
1.01
0.00
30.8
18.5
7.14
6.70
e9/l
3.23
365
3661
318
3182
1.00
0.00
4.1
4.1
1.35
1.38
mmol/l
0.71
295
2969
26
261
1.00
0.00
2.6
4.4
2.85
27.33
ug/l
0.86
21
214
10
97
1.03
0.00
1.3
1.2
—
—
—
0
0
18
175
1.03
0.00
1.7
1.2
—
—
—
0
0
376
3755
1.01
0.00
30.6
18.4
91.10
90.54
fl
1.38
371
3710
376
3755
1.01
0.00
30.6
18.4
30.41
30.33
pg
0.34
371
3709
376
3756
1.01
0.00
30.7
18.5
4.47
4.62
e12/l
5.14
365
3660
6
59
1.02
0.00
1.2
1.1
9.02
7.49
u/ml
—
6
35
0
5
0.00
0.00
0.0
1.2
—
41.00
—
0
5
0
8
0.00
0.00
0.0
1.4
—
84.38
—
0
8
0
5
0.00
0.00
0.0
3.8
—
—
—
0
0
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
0
8
0.00
0.00
0.0
2.5
—
9407.63
—
0
8
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
4.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
6
64
0.94
-0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
0.91
—
0
7
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
7
69
1.01
-0.00
2.7
1.3
—
—
—
0
0
6
64
0.94
-0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
48.50
—
0
6
5
54
0.93
-0.00
1.2
1.8
—
—
—
0
0
5
55
0.91
-0.00
1.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
1.20
—
0
6

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: ST19_FROSTBITE – Frostbite

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).