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Frostbite

ST19_FROSTBITE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 T33-T35
  • Cause of death: ICD-10 T33-T35

2 out of 7 registries used, show all original rules.

396

4. Check minimum number of events

None

396

5. Include endpoints

396

6. Filter based on genotype QC (FinnGen only)

396

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
S|T
Name in latin
Congelatio

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 396 134 262
Unadjusted period prevalence (%) 0.09 0.05 0.12
Median age at first event (years) 48.52 46.03 49.79

-FinnGen-

Age distribution of first events

020304050607080010203040506070AgeIndividuals

-FinnGen-

Year distribution of first events

1970197519801985199019952000200520102015202020230102030405060708090100YearIndividuals

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
359
Matched controls
3587
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
X31
ICD-10 Finland
Exposure to excessive natural cold
1080.5
149.5
136
*
T33.8
ICD-10 Finland
Superficial frostbite of ankle and foot
+∞
92.8
85
*
T33.5
ICD-10 Finland
Superficial frostbite of wrist and hand
+∞
72.4
67
*
T34.8
ICD-10 Finland
Frostbite with tissue necrosis of ankle and foot
+∞
43.6
41
*
T33.9
ICD-10 Finland
Superficial frostbite of other and unspecified sites
+∞
40.4
38
*
T68
ICD-10 Finland
Hypothermia
43.0
34.2
42
11
T34.5
ICD-10 Finland
Frostbite with tissue necrosis of wrist and hand
+∞
33.9
32
*
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
6.7
30.5
84
156
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
14.1
27.2
47
38
T35.5
ICD-10 Finland
Unspecified frostbite of lower limb
+∞
25.3
24
*
X59
ICD-10 Finland
Exposure to unspecified factor
4.0
25.2
120
398
N07BB01
ATC
disulfiram; oral
8.2
24.6
57
81
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
8.5
23.1
52
70
T33.4
ICD-10 Finland
Superficial frostbite of arm
+∞
22.1
21
*
T35.4
ICD-10 Finland
Unspecified frostbite of upper limb
+∞
22.1
21
*
X58
ICD-10 Finland
Exposure to other specified factors
4.0
22.0
100
314
T36
ICD-10 Finland
Poisoning by systemic antibiotics
7.1
18.7
47
75
N05AA02
ATC
levomepromazine; systemic
6.5
18.0
48
83
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
8.2
17.7
40
54
NHQ40
NOMESCO Finland
Amputation of toe
17.1
17.3
27
17
NDQ20
NOMESCO Finland
Amputation of finger
52.7
17.2
20
*
N05AH04
ATC
quetiapine; oral
3.3
17.2
100
374
T33.0
ICD-10 Finland
Superficial frostbite of head
+∞
16.8
16
*
N05AH03
ATC
olanzapine; systemic
4.8
16.4
57
135
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.7
16.3
77
244
SPAT1148
SPAT
Treatment of chronic ulcer or burn
3.6
16.2
80
263
AA1AD
NOMESCO Finland
CT of head and brain
2.9
15.2
107
452
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.7
15.2
134
650
F29
ICD-10 Finland
Unspecified nonorganic psychosis
5.4
14.1
43
88
R56.8
ICD-10 Finland
Other and unspecified convulsions
5.0
13.9
45
99
N06AX11
ATC
mirtazapine; oral
2.5
13.5
134
685
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
8.8
13.3
28
34
N05BA04
ATC
oxazepam; oral
2.7
13.3
111
513
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
9.9
13.2
26
28
S06.0
ICD-10 Finland
Concussion
3.7
13.1
61
190
N05CD07
ATC
temazepam; oral
3.4
12.8
67
228
G72.8
ICD-10 Finland
Other specified myopathies
16.2
12.8
20
13
A46
ICD-10 Finland
Erysipelas
3.2
12.7
71
254
F10.20
ICD-10 Finland
Alcohol dependence currently independent
8.1
12.7
28
37
T34.4
ICD-10 Finland
Frostbite with tissue necrosis of arm
+∞
12.6
12
*
W93
ICD-10 Finland
Exposure to excessive cold of man-made origin
+∞
12.6
12
*
T33.7
ICD-10 Finland
Superficial frostbite of knee and lower leg
+∞
12.6
12
*
F10.25
ICD-10 Finland
Alcohol dependence continuous use
9.5
12.5
25
28
N05AX08
ATC
risperidone; systemic
3.9
12.4
52
148
F10.49
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without information about seizures
22.2
12.1
17
8
F10.24
ICD-10 Finland
Alcohol depence active use
9.4
11.9
24
27
S97
ICPC
Chronic ulcer skin
4.9
11.6
38
85
T35.0
ICD-10 Finland
Superficial frostbite involving multiple body regions
+∞
11.5
11
*
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
3.6
11.4
54
170
W00
ICD-10 Finland
Fall on same level involving ice and snow
3.3
11.3
59
200
F32.9
ICD-10 Finland
Depressive episode, unspecified
3.1
11.2
66
242
QDG20
NOMESCO Finland
Operation for chronic ulcer or fistula of skin of lower limb
20.8
11.2
16
8
F05.9
ICD-10 Finland
Delirium, unspecified
11.1
10.9
20
19
F10.39
ICD-10 Finland
Withdrawal symptoms caused by alcohol UNS
11.1
10.9
20
19
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
3.5
10.8
51
160
ZZA00
NOMESCO Finland
Split skin graft
6.5
10.7
27
44
F10.40
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without seizures
10.5
10.6
20
20
NA1AD
NOMESCO Finland
Cervical spine CT examination
6.1
10.5
28
49
T34.9
ICD-10 Finland
Frostbite with tissue necrosis of other and unspecified sites
+∞
10.5
10
*
P15
ICPC
Chronic alcohol abuse
5.4
10.4
31
62
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.5
10.4
50
159
N05CF01
ATC
zopiclone; oral
2.2
9.5
120
669
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.9
9.5
61
236
F10.26
ICD-10 Finland
Alcohol dependence periodic alcoholism
7.6
9.4
21
29
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
3.6
9.3
42
128
SPAT1254
SPAT
Administration of medicine
2.6
9.1
71
309
S01.0
ICD-10 Finland
Open wound of scalp
3.5
9.1
42
130
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.3
9.0
91
455
N03AX16
ATC
pregabalin; oral
2.4
9.0
87
427
F10.09
ICD-10 Finland
Alcohol intoxication UNS
6.6
8.9
22
35
S18
ICPC
Laceration/cut
2.0
8.9
152
957
B18.2
ICD-10 Finland
Chronic viral hepatitis C
9.0
8.9
18
21
N02AA05
ATC
oxycodone; systemic
2.8
8.8
59
236
SPAT1149
SPAT
Suture or treatment of traumatic wound
2.8
8.8
59
236
F10.21
ICD-10 Finland
Alcohol dependence currently abstinent, but staying in restrictive environment
10.4
8.6
16
16
F19.1
ICD-10 Finland
Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances, harmful use
16.8
8.6
13
8
N05AB03
ATC
perphenazine; systemic, rectal
5.5
8.5
24
46
X39
ICD-10 Finland
Exposure to other and unspecified forces of nature
92.1
8.4
9
*
F10.2
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Dependence syndrome
11.1
8.4
15
14
T33.6
ICD-10 Finland
Superficial frostbite of hip and thigh
+∞
8.4
8
*
3039X
ICD-9 Finland
Alcohol dependence syndrome, Other and unspecified alcohol dependence
9.2
8.1
16
18
F19.20
ICD-10 Finland
Addiction relationship caused by several drugs in combination and by other psychoactive substances currently independent
22.6
8.1
11
5
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
3.4
8.0
38
121
N04AA02
ATC
biperiden; systemic
7.2
7.9
18
26
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
9.7
7.9
15
16
F10.30
ICD-10 Finland
Withdrawal symptoms caused by alcohol uncomplicated
9.7
7.9
15
16
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
3.1
7.8
42
146
QCB10
NOMESCO Finland
Major dressing of wound of skin of upper limb
6.2
7.8
20
34
N05AD01
ATC
haloperidol; systemic
5.0
7.8
24
51
N05AF03
ATC
chlorprothixene; systemic
4.9
7.7
24
52
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
3.4
7.5
36
115
QDD00
NOMESCO Finland
Dressing of major burn of lower limb
81.7
7.4
8
*
TQW10
NOMESCO Finland
Exchange of bandage for burn
81.7
7.4
8
*
N05BA01
ATC
diazepam; systemic, rectal
2.5
7.4
59
262
N05AF05
ATC
zuclopenthixol; systemic
11.2
7.4
13
12
N02AX02
ATC
tramadol; systemic, rectal
1.9
7.3
142
920
Y94.8
ICD-10 Finland
Other leisure activity accident
6.5
7.3
18
29
R41.0
ICD-10 Finland
Disorientation, unspecified
6.0
7.3
19
33
T34.7
ICD-10 Finland
Frostbite with tissue necrosis of knee and lower leg
+∞
7.3
7
*
T34.0
ICD-10 Finland
Frostbite with tissue necrosis of head
+∞
7.3
7
*
EBA00
NOMESCO Finland
Extraction of tooth
1.9
7.2
131
828
F20.9
ICD-10 Finland
Schizophrenia, unspecified
5.1
7.1
21
43
L17
ICPC
Foot/toe symptom/complaint
2.1
7.1
90
494
SPAT1263
SPAT
Sampling
1.8
7.0
154
1040
V03AA01
ATC
NA
7.8
7.0
15
20
P20
ICPC
Memory disturbance
2.9
6.9
41
153
F10.31
ICD-10 Finland
Withdrawal symptoms caused by alcohol with seizures
11.2
6.8
12
11
F10.05
ICD-10 Finland
Alcohol-related acute intoxication with coma
40.8
6.8
8
*
T51.0
ICD-10 Finland
Toxic effect: Ethanol
17.1
6.8
10
6
W19
ICD-10 Finland
Unspecified fall
2.8
6.7
42
161
F60.31
ICD-10 Finland
Emotionally unstable personality disorder, borderline condition
8.9
6.6
13
15
F10.9
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Unspecified mental and behavioural disorder
8.9
6.6
13
15
N03AX12
ATC
gabapentin; oral
2.4
6.6
56
254
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.0
6.6
37
132
T74.1
ICD-10 Finland
Physical abuse
6.4
6.5
16
26
SPAT1301
SPAT
No procedures
1.9
6.5
119
748
F15.5
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, psychotic disorder
71.1
6.4
7
*
3018X
ICD-9 Finland
Personality disorders, Other personality disorders[MUU TAI SEKAMUOTOINEN PERSOONALLISUUSHÄIRIÖ]
14.6
6.4
10
7
S22.3
ICD-10 Finland
Fracture of rib
3.1
6.4
33
112
W10
ICD-10 Finland
Fall on and from stairs and steps
3.9
6.4
25
68
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.3
6.4
62
300
J01FF01
ATC
clindamycin; systemic
2.0
6.4
95
554
F43.1
ICD-10 Finland
Post-traumatic stress disorder
7.2
6.3
14
20
T35.3
ICD-10 Finland
Unspecified frostbite of thorax, abdomen, lower back and pelvis
+∞
6.3
6
*
T35.7
ICD-10 Finland
Unspecified frostbite of unspecified site
+∞
6.3
6
*
P72
ICPC
Schizophrenia
6.5
6.2
15
24
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.0
6.1
33
116
N06AB04
ATC
citalopram; systemic
2.1
6.1
74
397
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.4
6.1
53
244
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
6.2
6.1
15
25
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
2.9
6.0
35
129
S61.9
ICD-10 Finland
Open wound of wrist and hand, part unspecified
4.2
6.0
21
52

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
25
36
7.35
16.73
2.0
1.4
2.09
1.37
promille
0.86
17
26
162
865
2.48
16.57
3.0
2.1
641.97
308.03
u/l
0.86
157
823
89
361
2.89
15.77
2.3
1.6
—
—
—
0
0
141
795
2.20
11.94
5.8
4.4
—
—
—
0
0
34
91
3.99
11.56
3.5
2.7
—
—
—
0
0
16
21
7.90
11.50
2.4
2.3
—
—
—
0
0
51
192
2.90
10.16
3.0
2.1
—
—
—
0
0
92
468
2.26
9.78
1.9
1.6
1246.09
1137.78
nmol/l
0.50
75
354
197
1329
1.96
9.76
9.0
7.3
1.20
1.21
mmol/l
0.62
174
1135
171
1104
1.97
9.59
4.5
3.5
264.92
65.21
ng/l
0.39
122
732
52
206
2.75
9.42
3.2
2.0
—
—
—
0
0
70
324
2.41
9.22
8.7
10.1
1.40
1.08
mmol/l
0.24
50
257
52
209
2.71
9.16
3.2
2.0
—
—
—
0
0
52
209
2.71
9.16
3.2
2.0
—
—
—
0
0
45
168
2.89
9.09
3.5
2.1
—
—
—
0
0
12
15
8.22
8.90
2.1
2.5
122.71
97.25
umol/l
—
7
8
182
1225
1.90
8.81
7.7
6.4
1.20
1.21
mmol/l
1.05
173
1118
40
144
2.98
8.62
4.4
3.0
—
—
—
0
0
49
198
2.68
8.53
7.3
6.9
—
—
—
0
0
147
935
1.91
8.36
3.7
2.6
59.08
57.03
u/l
0.19
138
874
175
1191
1.84
7.96
6.3
5.1
34.67
35.88
g/l
1.60
160
1121
214
1550
1.83
7.93
5.8
6.3
11.31
11.87
umol/l
0.31
203
1471
49
206
2.57
7.88
3.2
1.8
—
—
—
0
0
166
1122
1.83
7.65
10.7
8.5
1.32
1.24
inr
0.53
48
339
73
373
2.17
7.56
6.9
6.1
1.07
1.01
mmol/l
0.94
68
350
286
2287
1.90
7.49
7.4
7.4
75.47
77.08
u/l
0.41
276
2153
56
260
2.34
7.27
3.1
3.9
—
—
—
0
0
226
1728
1.72
6.41
7.3
5.1
6.66
6.70
mmol/l
0.08
214
1598
52
251
2.23
6.16
3.0
3.8
2.89
1.82
mmol/l
1.37
37
194
49
241
2.18
5.54
2.2
2.2
5.54
9.78
ug/l
1.33
43
215
151
1070
1.66
5.45
3.8
3.3
37.21
33.99
u/l
0.27
143
1026
62
343
1.96
5.13
13.8
22.2
1.02
1.21
inr
—
6
45
87
544
1.77
4.89
1.6
1.7
113889315.36
8492995.78
pmol/l
0.44
72
471
49
258
2.03
4.65
6.1
8.1
1.87
1.48
mmol/l
0.56
43
248
111
753
1.66
4.62
3.8
2.9
—
—
—
0
0
139
1007
1.59
4.40
5.2
5.7
—
—
—
0
0
71
434
1.77
4.29
3.1
2.1
—
—
—
0
0
13
36
3.70
4.24
18.2
19.9
71692.77
1328.36
nmol/l
0.47
13
36
125
891
1.59
4.21
2.6
2.3
—
—
—
0
0
26
110
2.46
4.16
7.5
4.4
—
—
—
0
0
173
1331
1.53
4.14
5.4
4.1
—
—
—
0
0
264
2235
1.54
3.96
4.8
3.2
53.10
49.45
u/l
0.26
255
2120
100
686
1.61
3.92
2.2
1.9
3.02
2.94
mg/l
0.11
89
599
30
145
2.16
3.58
4.3
3.1
—
—
—
0
0
96
667
1.58
3.54
5.6
3.4
1.02
1.02
kg/l
0.14
17
93
107
765
1.55
3.47
5.9
3.6
0.00
0.00
estimate
0.50
32
271
38
204
1.95
3.44
4.2
3.1
7.41
7.42
ph
—
5
26
38
205
1.94
3.40
4.2
3.1
5.52
5.10
kpa
1.36
32
193
7
10
7.10
3.37
5.3
2.8
—
—
—
0
0
42
237
1.86
3.29
6.9
9.4
—
—
—
0
0
119
889
1.48
3.10
2.9
3.2
2.34
2.35
mmol/l
0.42
102
781
78
532
1.58
3.09
4.3
3.5
81.78
288.71
ng/l
1.55
58
405
38
213
1.87
3.05
3.7
3.2
—
—
—
0
0
20
88
2.34
2.99
7.0
3.8
3.80
3.92
mmol/l
0.47
20
81
238
2033
1.43
2.98
5.1
3.9
—
—
—
0
0
178
1446
1.42
2.95
5.6
4.5
0.00
0.00
estimate
0.00
35
285
45
271
1.75
2.87
3.1
2.3
0.21
0.22
g/l
0.46
40
249
51
777
0.61
2.85
2.1
2.9
0.65
0.77
ug/l
0.61
30
474
190
1569
1.41
2.83
6.2
5.8
1.87
1.90
e9/l
0.16
163
1412
184
1518
1.40
2.73
6.2
5.7
0.63
0.59
e9/l
1.07
154
1341
178
1467
1.39
2.62
4.7
3.3
0.00
0.00
estimate
0.00
33
266
32
180
1.85
2.56
3.5
2.8
164.93
177.02
ng/l
0.05
27
155
174
1435
1.38
2.53
6.2
6.0
2.85
2.81
%
0.09
164
1357
116
893
1.42
2.53
3.4
3.1
58.93
119.86
e6/l
0.37
89
694
207
1758
1.37
2.50
9.4
9.3
4.45
4.14
e9/l
0.98
176
1549
183
1524
1.37
2.50
6.2
5.7
0.04
0.04
e9/l
0.30
155
1352
188
1574
1.37
2.47
6.3
6.1
0.20
0.19
e9/l
0.33
160
1411
97
725
1.45
2.47
6.2
6.6
—
—
—
0
0
89
656
1.46
2.44
1.9
1.8
1.16
1.29
mg/l
0.16
63
495
90
1181
0.69
2.43
2.5
2.6
—
—
—
0
0
87
639
1.46
2.43
4.6
3.3
—
—
—
0
0
29
161
1.86
2.42
13.4
13.5
—
—
—
0
0
179
1491
1.37
2.42
6.3
6.0
26.29
27.63
%
0.95
166
1411
174
1443
1.37
2.42
7.1
6.3
8.66
8.75
%
0.11
163
1374
43
270
1.66
2.38
1.9
1.5
—
—
—
0
0
29
164
1.83
2.30
2.4
2.5
0.29
0.14
e6/l
0.40
29
157
11
41
2.73
2.29
1.3
1.2
—
—
—
0
0
106
817
1.41
2.27
4.5
3.8
—
—
—
0
0
85
630
1.44
2.26
1.4
1.5
18.66
20.85
nmol/l
0.72
75
541
173
1447
1.35
2.23
4.7
3.3
0.00
0.00
estimate
0.00
30
276
24
129
1.92
2.22
2.7
2.1
—
—
—
0
0
129
1036
1.36
2.15
3.9
3.5
142.61
121.52
e6/l
0.09
92
738
103
798
1.39
2.13
4.9
3.9
7.41
7.40
ph
0.27
16
149
82
611
1.43
2.11
2.9
2.5
4.42
4.16
e6/l
0.08
73
531
10
231
0.42
2.07
1.0
1.4
—
—
—
0
0
0
57
0.00
2.07
0.0
1.2
—
14.64
—
0
50
133
1081
1.35
2.03
2.2
1.9
88.83
94.27
pmol/l
0.75
79
568
14
63
2.27
2.03
3.9
3.1
4.85
5.07
kpa
0.94
14
63
14
63
2.27
2.03
3.9
3.1
1.83
2.34
mmol/l
—
9
44
14
63
2.27
2.03
3.9
3.1
8.09
8.59
kpa
0.54
14
63
174
1472
1.32
2.02
6.4
5.8
58.37
57.38
%
0.53
162
1400
12
51
2.40
1.97
1.9
1.4
—
—
—
0
0
165
1398
1.31
1.86
5.7
6.1
0.64
0.66
%
0.14
154
1326
14
66
2.16
1.84
3.1
2.8
—
—
—
0
0
25
407
0.59
1.82
1.2
1.4
—
—
—
0
0
245
2194
1.31
1.81
3.7
3.4
14.75
14.74
pmol/l
0.03
221
1985
7
23
3.08
1.80
9.3
8.8
0.61
0.58
mmol/l
—
7
23
98
778
1.35
1.73
3.3
3.0
—
—
—
0
0
112
908
1.33
1.71
3.3
3.2
7.55
8.44
mmol/l
0.97
100
770
31
197
1.62
1.68
5.7
2.6
4.61
3.97
e9/l
0.53
26
161
33
219
1.55
1.52
3.4
5.4
0.00
0.16
%
—
10
70
61
461
1.38
1.47
2.0
3.2
2.45
2.45
mmol/l
0.21
48
400
330
3115
1.36
1.46
24.3
15.1
139.42
139.65
mmol/l
0.88
324
3028
14
73
1.95
1.45
3.9
3.2
7.40
7.42
ph
1.03
14
63
35
238
1.52
1.45
3.3
5.1
1.09
0.92
%
0.10
11
79
12
59
2.07
1.45
3.0
3.0
5.92
4.49
e9/l
0.71
12
59
16
88
1.85
1.43
1.6
1.2
—
—
—
0
0
33
223
1.52
1.41
2.4
2.8
83.40
74.21
e9/l
0.44
23
170
12
60
2.03
1.39
3.4
3.7
64.67
57.62
%
0.91
12
60
29
191
1.56
1.39
4.6
3.9
128.25
83.94
ng/l
1.12
22
176
330
3127
1.33
1.32
24.2
15.2
4.00
3.98
mmol/l
0.57
323
3038
36
252
1.47
1.32
3.3
3.6
—
—
—
0
0
74
587
1.32
1.31
3.2
2.6
493.72
572.92
mosm/kgh2o
2.30
64
500
9
43
2.12
1.31
1.1
1.1
—
—
—
0
0
9
43
2.12
1.31
1.6
1.3
—
—
—
0
0
31
213
1.49
1.25
3.5
5.4
0.00
0.19
%
—
10
63
152
1328
1.23
1.23
11.8
9.4
0.00
0.00
e9/l
0.55
128
1090
96
796
1.27
1.22
3.3
3.0
0.21
0.47
e6/l
1.35
73
603
328
3115
1.31
1.22
22.5
13.1
24.48
23.67
mg/l
0.19
282
2429
57
440
1.35
1.22
2.1
1.6
—
—
—
0
0
8
38
2.13
1.19
1.3
1.1
—
—
—
0
0
115
1335
0.80
1.17
3.4
4.5
1.66
2.32
ug/l
1.05
102
1219
11
58
1.92
1.13
2.1
3.6
—
—
—
0
0
237
2183
1.21
1.10
4.0
3.7
10.93
10.59
mm/h
0.13
222
2009
11
59
1.89
1.08
3.3
2.4
—
—
—
0
0
16
97
1.68
1.08
1.1
1.3
—
4.42
—
0
6
7
33
2.14
1.06
1.4
2.0
33.86
33.52
pg
—
7
33
84
701
1.25
1.02
4.1
4.8
—
—
—
0
0
41
310
1.36
1.02
1.9
2.7
2.25
1.86
%
0.75
36
283
7
35
2.02
1.00
1.1
1.7
—
—
—
0
0
7
35
2.02
1.00
1.1
1.7
—
—
—
0
0
7
35
2.02
1.00
1.1
1.7
—
—
—
0
0
7
35
2.02
1.00
1.1
1.7
—
—
—
0
0
46
356
1.33
0.99
1.8
1.5
—
—
—
0
0
30
216
1.42
0.99
3.3
5.1
0.40
0.36
%
—
10
59
28
382
0.71
0.95
2.1
2.3
182.37
119.70
ug/g
0.24
21
305
7
37
1.91
0.94
16.9
1.6
13.57
13.15
%
—
7
37
7
37
1.91
0.94
1.4
4.1
—
—
—
0
0
93
1081
0.82
0.94
1.9
2.0
—
—
—
0
0
6
29
2.08
0.89
4.8
3.1
119.38
21.12
mg/l
—
6
24
16
103
1.58
0.89
1.6
1.8
—
—
—
0
0
66
545
1.25
0.88
2.0
1.6
—
—
—
0
0
54
437
1.27
0.86
2.7
2.3
11.63
13.72
umol/l
1.16
47
407
221
2052
1.17
0.84
4.3
3.6
—
—
—
0
0
139
1243
1.18
0.84
2.8
2.4
129.78
144.99
ug/l
0.37
126
1146
50
403
1.28
0.82
2.8
2.3
2.17
2.33
g/l
1.15
44
372
16
106
1.53
0.80
1.3
1.4
127.20
256.48
miu/ml
—
5
47
99
863
1.20
0.79
1.4
1.5
—
—
—
0
0
0
28
0.00
0.76
0.0
1.4
—
—
—
0
0
0
28
0.00
0.76
0.0
1.1
—
0.08
—
0
5
5
24
2.10
0.74
1.0
1.8
9.64
12.61
%
—
5
24
55
455
1.24
0.74
3.0
2.8
2.97
1.53
e6/l
0.89
24
256
9
55
1.65
0.74
1.0
1.1
—
—
—
0
0
5
25
2.01
0.73
1.8
1.2
—
—
—
0
0
23
304
0.74
0.67
1.3
1.3
—
—
—
0
0
10
155
0.64
0.67
1.0
1.1
—
—
—
0
0
13
86
1.53
0.67
1.5
3.3
—
—
—
0
0
33
261
1.29
0.65
3.7
4.3
—
—
—
0
0
95
841
1.17
0.64
3.4
4.1
8.65
9.28
mg/mmol
0.07
70
575
10
150
0.66
0.59
2.3
1.5
—
—
—
0
0
29
363
0.78
0.59
1.4
1.5
—
—
—
0
0
0
23
0.00
0.58
0.0
1.1
—
154840.00
—
0
16
25
317
0.77
0.56
1.6
1.7
—
—
—
0
0
341
3321
1.19
0.56
11.8
9.6
28.59
29.47
u/l
0.36
332
3225
6
37
1.63
0.56
3.8
3.2
—
—
—
0
0
95
852
1.15
0.55
4.1
3.0
—
—
—
0
0
9
60
1.51
0.54
1.3
1.4
1.89
154.48
e6/l
—
9
48
6
38
1.59
0.54
1.2
1.2
—
—
—
0
0
6
100
0.59
0.52
8.3
10.3
—
—
—
0
0
79
703
1.15
0.51
2.4
2.0
—
—
—
0
0
43
365
1.20
0.48
1.4
1.3
—
—
—
0
0
7
50
1.41
0.45
1.1
1.9
52.00
65.17
%
—
7
50
17
130
1.32
0.44
1.4
1.3
—
—
—
0
0
7
51
1.38
0.44
1.3
2.1
—
—
—
0
0
119
1100
1.12
0.44
2.8
2.2
70.66
74.27
nmol/l
0.62
111
985
5
31
1.62
0.43
1.4
1.2
—
—
—
0
0
23
185
1.26
0.43
5.9
2.4
—
—
—
0
0
86
781
1.13
0.42
1.8
1.7
1.22
1.46
mmol/l
2.85
77
668
10
70
1.44
0.42
1.3
1.2
—
—
—
0
0
29
241
1.22
0.41
1.1
1.1
—
—
—
0
0
5
33
1.52
0.41
1.4
1.4
2.68
2.62
g/l
—
5
22
5
33
1.52
0.41
1.4
1.4
0.34
0.31
g/l
—
5
21
5
33
1.52
0.41
1.4
1.4
5.92
6.37
g/l
—
5
22
28
335
0.82
0.41
1.3
1.2
—
—
—
0
0
5
34
1.48
0.40
1.4
1.4
—
—
—
0
0
87
795
1.12
0.39
2.8
3.3
59.24
143.64
mg/l
0.49
63
542
272
2635
1.10
0.38
23.6
15.9
13.87
13.56
%
1.67
267
2588
5
37
1.36
0.37
1.2
1.1
0.72
2.44
u/ml
—
5
14
28
331
0.83
0.37
1.9
1.4
—
—
—
0
0
55
613
0.88
0.35
1.5
1.3
2.89
2.47
g/l
0.45
35
396
6
46
1.31
0.33
2.8
3.1
33.18
2.76
u/ml
—
6
41
22
187
1.19
0.27
1.7
1.3
—
23.98
—
0
10
8
67
1.20
0.26
1.0
1.1
—
—
—
0
0
19
160
1.20
0.26
1.3
2.4
—
—
—
0
0
9
72
1.26
0.26
1.7
1.3
—
—
—
0
0
296
3017
0.93
0.25
4.1
4.1
1.34
1.39
mmol/l
1.03
273
2810
6
81
0.74
0.24
1.0
3.6
24.70
134.08
mg/l
—
6
66
334
3291
1.10
0.24
21.7
11.9
—
—
—
0
0
42
381
1.11
0.23
3.3
2.3
22.39
24.71
%
0.23
29
338
5
38
1.32
0.23
1.4
1.5
1.63
0.36
nmol/l
—
5
29
7
93
0.75
0.22
1.3
1.2
—
—
—
0
0
33
367
0.89
0.22
2.5
2.3
15.27
14.19
nmol/l
0.35
26
337
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
40
364
1.11
0.21
1.7
1.7
—
—
—
0
0
0
12
0.00
0.21
0.0
1.5
—
29.50
—
0
12
0
12
0.00
0.21
0.0
3.1
—
8.98
—
0
12
5
43
1.16
0.21
1.2
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
288
2930
0.94
0.20
3.7
3.8
1.33
1.32
mmol/l
0.08
262
2721
6
50
1.20
0.20
1.0
1.1
—
158.40
—
0
10
42
386
1.10
0.19
1.4
1.4
221.82
436.76
titre
1.88
11
74
305
3092
0.94
0.17
4.5
4.5
2.67
2.78
mmol/l
1.13
281
2866
49
457
1.08
0.17
1.2
1.3
28.64
30.64
iu/ml
0.05
19
143
6
76
0.79
0.15
2.7
3.7
—
—
—
0
0
300
3038
0.95
0.15
4.2
4.2
4.48
4.61
mmol/l
1.37
277
2843
65
679
0.95
0.12
1.2
1.2
1.07
1.24
u/ml
0.20
12
181
79
760
1.05
0.12
2.3
2.7
346.99
5712.66
umol/l
2.41
69
659
5
44
1.14
0.10
1.4
1.0
0.14
1.60
u/ml
—
5
16
10
87
1.15
0.09
1.3
1.2
—
72.22
—
0
9
5
48
1.04
0.09
1.2
1.1
0.40
3.63
u/ml
—
5
20
298
2953
1.04
0.09
20.1
13.5
40.43
41.13
%
0.65
191
2268
292
2947
0.97
0.09
4.5
4.1
5.92
5.91
mmol/l
0.01
262
2700
6
55
1.09
0.09
1.0
1.1
—
—
—
0
0
6
55
1.09
0.09
1.0
1.1
—
—
—
0
0
10
113
0.88
0.08
1.2
1.2
—
—
—
0
0
353
3548
0.95
0.07
30.7
18.6
7.15
6.70
e9/l
3.34
342
3454
7
81
0.86
0.07
1.0
3.6
17.66
29.31
mg/l
—
7
66
353
3547
0.96
0.07
30.5
18.6
4.48
4.62
e12/l
4.53
342
3453
353
3546
0.96
0.06
30.4
18.5
91.17
90.54
fl
1.56
348
3502
353
3546
0.96
0.06
30.4
18.5
30.44
30.33
pg
0.50
348
3501
273
2710
1.02
0.05
4.6
4.1
1.92
1.90
mu/l
0.11
249
2494
21
221
0.95
0.04
1.1
1.4
—
—
—
0
0
353
3542
0.97
0.04
30.3
18.6
243.49
245.28
e9/l
0.18
342
3456
11
119
0.92
0.04
2.3
2.6
—
—
—
0
0
24
230
1.05
0.03
1.3
1.4
—
—
—
0
0
24
250
0.96
0.03
2.0
4.6
2.78
28.41
ug/l
0.87
19
205
15
159
0.94
0.03
1.3
1.2
—
—
—
0
0
18
171
1.06
0.03
1.7
1.2
—
—
—
0
0
274
2747
0.99
0.01
5.9
5.4
39.68
39.67
mmol/mol
0.01
252
2574
43
424
1.02
0.00
1.3
1.2
1.21
6.39
u/ml
2.53
15
163
14
141
0.99
0.00
1.1
1.0
—
—
—
0
0
13
126
1.03
0.00
1.9
3.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
3.1
—
—
—
0
0
9
91
0.99
0.00
1.3
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
48.50
—
0
6
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
5
52
0.96
0.00
1.0
1.7
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
0.43
—
0
6
0
8
0.00
0.00
0.0
2.5
—
9407.63
—
0
8
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
3.8
—
—
—
0
0
5
49
1.02
0.00
7.6
2.7
—
—
—
0
0
5
52
0.96
0.00
1.2
1.1
8.87
8.01
u/ml
—
5
30
7
74
0.94
0.00
1.0
2.3
36.43
38.49
g/l
—
7
66
8
83
0.96
0.00
1.0
1.2
—
—
—
0
0
7
69
1.01
0.00
2.7
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
41.00
—
0
5
0
6
0.00
0.00
0.0
1.2
—
1.20
—
0
6
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: ST19_FROSTBITE – Frostbite

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).