This is a non-core endpoint: only basic statistics are computed.
Frostbite with tissue necrosis
ST19_FROST_W_TISSUE_NECROS
No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
116 |
4. Check minimum number of eventsNone |
116 |
5. Include endpointsNone |
116 |
6. Filter based on genotype QC (FinnGen only) |
109 |
Control definitions (FinnGen only)
- Control exclude
- ST19_FROSTBITE
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- T3[3-5]
- Name in latin
- Congelatio cum necrosi textus
Similar endpoints
↥List of similar endpoints to
Frostbite with tissue necrosis
based on the number of shared cases.
Similar with more cases:
- Frostbite
- Injury, poisoning and certain other consequences of external causes
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 109 | 35 | 74 |
| Unadjusted period prevalence (%) | 0.03 | 0.01 | 0.03 |
| Median age at first event (years) | 50.38 | 41.35 | 54.65 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 116
- Matched controls
- 1160
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
X31
ICD-10 Finland
Exposure to excessive natural cold
+∞
64.8
56
*
T34.8
ICD-10 Finland
Frostbite with tissue necrosis of ankle and foot
+∞
47.1
42
*
T34.5
ICD-10 Finland
Frostbite with tissue necrosis of wrist and hand
+∞
39.9
36
*
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
18.1
37.4
34
26
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
10.9
28.1
36
46
T68
ICD-10 Finland
Hypothermia
197.2
17.0
17
*
N05AH04
ATC
quetiapine; oral
5.0
14.8
43
122
X59
ICD-10 Finland
Exposure to unspecified factor
4.9
14.8
46
138
X58
ICD-10 Finland
Exposure to other specified factors
5.2
14.3
38
100
N05AH03
ATC
olanzapine; systemic
7.1
14.2
24
41
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
21.6
14.0
20
11
T36
ICD-10 Finland
Poisoning by systemic antibiotics
16.6
13.9
22
16
T33.5
ICD-10 Finland
Superficial frostbite of wrist and hand
+∞
13.8
13
*
T34.4
ICD-10 Finland
Frostbite with tissue necrosis of arm
+∞
13.8
13
*
NDQ20
NOMESCO Finland
Amputation of finger
157.7
13.8
14
*
ZZA00
NOMESCO Finland
Split skin graft
26.2
11.9
16
7
N07BB01
ATC
disulfiram; oral
9.8
11.8
24
30
T33.8
ICD-10 Finland
Superficial frostbite of ankle and foot
+∞
11.6
11
*
T34.9
ICD-10 Finland
Frostbite with tissue necrosis of other and unspecified sites
+∞
11.6
11
*
NHQ40
NOMESCO Finland
Amputation of toe
18.3
10.7
16
10
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
10.1
9.7
19
22
QDG20
NOMESCO Finland
Operation for chronic ulcer or fistula of skin of lower limb
+∞
9.5
9
*
P15
ICPC
Chronic alcohol abuse
11.5
9.4
17
17
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
5.1
9.0
21
48
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
13.0
8.9
15
13
F10.39
ICD-10 Finland
Withdrawal symptoms caused by alcohol UNS
54.2
8.8
10
*
N05CD07
ATC
temazepam; oral
4.8
8.7
22
54
J01FF01
ATC
clindamycin; systemic
3.2
8.0
46
199
SPAT1148
SPAT
Treatment of chronic ulcer or burn
3.9
8.0
27
83
X39
ICD-10 Finland
Exposure to other and unspecified forces of nature
85.3
7.5
8
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.5
7.4
31
110
N05AA02
ATC
levomepromazine; systemic
8.9
7.4
15
19
T34.7
ICD-10 Finland
Frostbite with tissue necrosis of knee and lower leg
+∞
7.4
7
*
T34.0
ICD-10 Finland
Frostbite with tissue necrosis of head
+∞
7.4
7
*
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
11.1
7.2
13
13
A46
ICD-10 Finland
Erysipelas
3.7
7.2
27
89
F32.9
ICD-10 Finland
Depressive episode, unspecified
3.9
7.2
24
73
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
4.7
7.1
18
44
F10.25
ICD-10 Finland
Alcohol dependence continuous use
12.0
7.0
12
11
EBA00
NOMESCO Finland
Extraction of tooth
2.8
6.8
54
275
QCB10
NOMESCO Finland
Major dressing of wound of skin of upper limb
11.0
6.7
12
12
AA1AD
NOMESCO Finland
CT of head and brain
2.9
6.5
40
177
F10.20
ICD-10 Finland
Alcohol dependence currently independent
15.5
6.5
10
7
W00
ICD-10 Finland
Fall on same level involving ice and snow
3.9
6.5
21
62
S97
ICPC
Chronic ulcer skin
5.8
6.3
17
33
T35.4
ICD-10 Finland
Unspecified frostbite of upper limb
+∞
6.3
6
*
T35.5
ICD-10 Finland
Unspecified frostbite of lower limb
+∞
6.3
6
*
F10.49
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without information about seizures
+∞
6.3
6
*
QCB05
NOMESCO Finland
Revision of wound of skin of upper limb
+∞
6.3
6
*
P29
ICPC
Psychological sympt/compl other
4.5
6.1
16
40
N05BA04
ATC
oxazepam; oral
2.9
6.1
38
169
N05BA01
ATC
diazepam; systemic, rectal
3.7
6.1
21
65
N05AF03
ATC
chlorprothixene; systemic
16.1
6.0
9
6
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
61
355
2.51
5.61
3.8
5.4
34.40
35.75
g/l
0.73
56
341
29
127
2.71
4.68
2.4
2.0
1.88
1.47
%
0.93
23
114
20
78
2.89
3.97
6.0
4.2
2.08
1.71
mmol/l
0.13
13
56
30
157
2.23
3.24
1.8
1.6
953.57
1197.00
nmol/l
1.03
23
124
20
93
2.39
2.81
15.2
13.9
1.59
0.84
mmol/l
0.44
13
78
5
6
8.63
2.77
1.8
1.3
—
—
—
0
0
26
142
2.07
2.49
1.5
1.8
—
—
—
0
0
44
311
1.67
1.83
2.6
1.8
89.42
93.56
pmol/l
0.34
27
155
53
394
1.64
1.81
12.8
12.6
1.13
1.24
inr
—
10
105
12
57
2.23
1.61
1.3
1.6
—
—
—
0
0
32
448
0.61
1.60
3.8
4.8
1.24
2.72
ug/l
1.31
27
398
18
103
1.88
1.51
1.4
1.7
—
—
—
0
0
7
29
2.50
1.41
1.7
1.9
—
—
—
0
0
17
99
1.84
1.36
1.4
1.7
—
—
—
0
0
6
25
2.47
1.26
13.8
4.6
3.58
3.98
mmol/l
—
6
25
10
50
2.09
1.20
1.5
1.3
—
—
—
0
0
0
33
0.00
1.18
0.0
2.1
—
—
—
0
0
25
348
0.64
1.14
3.4
4.2
31.23
21.87
%
1.27
11
158
7
30
2.42
1.14
1.7
2.1
—
—
—
0
0
18
113
1.70
1.14
14.4
8.1
103.33
104.26
mmol/l
0.36
18
113
52
417
1.45
1.13
2.9
2.8
—
—
—
0
0
5
21
2.44
1.10
1.0
1.3
—
—
—
0
0
5
21
2.44
1.10
1.0
1.3
—
—
—
0
0
18
264
0.62
1.03
2.7
2.9
0.73
0.75
ug/l
0.04
11
174
0
29
0.00
0.99
0.0
1.5
—
—
—
0
0
0
29
0.00
0.99
0.0
1.5
—
—
—
0
0
0
29
0.00
0.99
0.0
1.6
—
—
—
0
0
0
29
0.00
0.99
0.0
1.5
—
—
—
0
0
0
28
0.00
0.99
0.0
2.3
—
0.00
—
0
28
0
30
0.00
0.99
0.0
1.5
—
—
—
0
0
53
626
0.72
0.97
3.1
3.2
—
—
—
0
0
43
342
1.41
0.95
2.8
3.1
28.59
35.96
ng/l
0.37
27
225
16
103
1.64
0.93
6.7
7.3
—
—
—
0
0
41
325
1.40
0.92
3.3
3.1
—
—
—
0
0
8
45
1.83
0.86
1.4
1.8
—
—
—
0
0
11
65
1.76
0.86
3.3
2.6
85.33
60.11
ml/min/173m2
—
6
27
6
32
1.92
0.83
1.5
2.6
—
7219.44
—
0
8
28
211
1.43
0.82
2.8
2.5
—
—
—
0
0
14
90
1.63
0.82
2.4
3.4
—
—
—
0
0
0
24
0.00
0.80
0.0
1.7
—
—
—
0
0
0
25
0.00
0.80
0.0
1.7
—
—
—
0
0
0
26
0.00
0.79
0.0
2.3
—
0.00
—
0
26
0
26
0.00
0.79
0.0
2.3
—
0.00
—
0
26
24
177
1.45
0.79
1.4
1.6
476.74
455.06
pmol/l
0.10
19
158
100
1052
0.64
0.78
29.7
19.5
39.59
41.04
%
1.02
92
996
5
26
1.96
0.71
2.4
2.0
219.40
219.85
%
—
5
26
11
72
1.58
0.61
1.5
2.2
6.68
12.54
ug/l
0.55
11
64
0
22
0.00
0.60
0.0
1.5
—
0.12
—
0
6
0
22
0.00
0.60
0.0
1.1
—
—
—
0
0
82
881
0.76
0.60
4.1
3.8
1.34
1.31
mmol/l
0.18
76
807
0
23
0.00
0.59
0.0
1.9
—
—
—
0
0
0
23
0.00
0.59
0.0
1.1
—
—
—
0
0
75
814
0.78
0.59
5.0
4.0
1.87
1.92
mu/l
0.16
68
735
85
908
0.76
0.58
4.4
4.2
1.34
1.38
mmol/l
0.54
80
835
14
185
0.72
0.47
1.6
1.6
—
—
—
0
0
84
889
0.80
0.44
4.8
4.1
6.05
5.98
mmol/l
0.14
79
810
5
31
1.64
0.43
1.4
2.9
—
—
—
0
0
8
58
1.41
0.42
24.7
11.4
0.60
0.73
%
—
8
58
8
59
1.38
0.42
25.0
11.4
1.71
1.47
%
—
8
59
0
15
0.00
0.41
0.0
1.3
—
169.31
—
0
15
0
17
0.00
0.41
0.0
1.6
—
—
—
0
0
20
161
1.29
0.40
4.2
3.8
42.71
320.98
ng/l
0.82
14
126
0
18
0.00
0.40
0.0
1.7
—
—
—
0
0
0
18
0.00
0.40
0.0
1.7
—
—
—
0
0
6
45
1.35
0.34
6.3
2.7
1.30
1.36
%
—
6
45
19
156
1.26
0.33
1.8
2.5
1.29
0.80
e6/l
—
8
89
7
98
0.70
0.32
1.4
1.4
—
—
—
0
0
56
515
1.17
0.32
8.5
10.3
4.31
4.23
e9/l
0.07
46
452
30
264
1.18
0.28
3.7
4.0
8.31
12.14
mg/mmol
0.37
22
171
8
65
1.25
0.28
2.9
1.8
—
—
—
0
0
83
866
0.85
0.27
14.5
12.6
89.78
84.91
ml/min/173m2
0.76
70
709
9
74
1.23
0.26
3.1
1.9
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.6
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.7
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
5.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.7
—
—
—
0
0
0
12
0.00
0.21
0.0
1.7
—
—
—
0
0
0
12
0.00
0.21
0.0
1.8
—
—
—
0
0
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.7
—
—
—
0
0
0
13
0.00
0.21
0.0
1.6
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.7
—
—
—
0
0
0
13
0.00
0.21
0.0
1.7
—
—
—
0
0
0
13
0.00
0.21
0.0
1.4
—
8.28
—
0
13
0
14
0.00
0.20
0.0
3.0
—
—
—
0
0
22
246
0.87
0.18
1.9
3.0
1701.35
1277.05
ng/l
0.13
17
199
29
267
1.11
0.15
2.7
2.9
0.36
0.42
e6/l
0.08
21
203
12
134
0.88
0.09
2.7
2.2
—
—
—
0
0
19
205
0.91
0.08
1.8
1.6
1.59
1.39
mg/l
0.13
14
156
15
138
1.10
0.07
1.1
1.2
16.00
30.26
iu/ml
—
5
48
12
128
0.93
0.03
1.8
2.4
9.82
14.49
umol/l
1.25
12
122
94
932
1.05
0.02
20.0
13.4
30.97
24.35
mg/l
1.10
80
728
67
664
1.02
0.00
3.7
3.7
13.16
10.25
mm/h
0.65
62
611
12
117
1.03
0.00
2.6
2.1
—
—
—
0
0
33
335
0.98
0.00
4.8
3.3
—
—
—
0
0
65
653
0.99
0.00
3.8
3.4
14.96
14.82
pmol/l
0.17
59
579
15
146
1.03
0.00
1.7
2.6
5.00
1.95
e6/l
—
5
80
0
7
0.00
0.00
0.0
2.1
—
13.39
—
0
7
0
7
0.00
0.00
0.0
2.3
—
870.57
—
0
7
0
7
0.00
0.00
0.0
1.9
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.7
—
10.57
—
0
7
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
2.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
0.31
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
1843.17
—
0
6
0
5
0.00
-0.00
0.0
1.2
—
5.73
—
0
5
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
7.2
—
200.34
—
0
5
0
8
0.00
-0.00
0.0
1.8
—
7.74
—
0
8
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.8
—
38.80
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
50
1.00
-0.00
1.2
1.0
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: ST19_FROST_W_TISSUE_NECROS – Frostbite with tissue necrosis
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).