This is a non-core endpoint: only basic statistics are computed.
Frostbite with tissue necrosis
ST19_FROST_W_TISSUE_NECROS
No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
111 |
4. Check minimum number of eventsNone |
111 |
5. Include endpointsNone |
111 |
6. Filter based on genotype QC (FinnGen only) |
111 |
Control definitions (FinnGen only)
- Control exclude
- ST19_FROSTBITE
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- T3[3-5]
- Name in latin
- Congelatio cum necrosi textus
Similar endpoints
↥List of similar endpoints to
Frostbite with tissue necrosis
based on the number of shared cases.
Similar with more cases:
- Frostbite
- Injury, poisoning and certain other consequences of external causes
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 111 | 35 | 76 |
| Unadjusted period prevalence (%) | 0.03 | 0.01 | 0.03 |
| Median age at first event (years) | 49.45 | 38.89 | 54.31 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 105
- Matched controls
- 1050
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
X31
ICD-10 Finland
Exposure to excessive natural cold
882.7
54.7
49
*
T34.8
ICD-10 Finland
Frostbite with tissue necrosis of ankle and foot
+∞
42.6
38
*
T34.5
ICD-10 Finland
Frostbite with tissue necrosis of wrist and hand
+∞
34.2
31
*
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
17.1
19.2
31
25
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
13.4
16.3
29
29
N07BB01
ATC
disulfiram; oral
20.3
16.2
24
15
T68
ICD-10 Finland
Hypothermia
+∞
16.0
15
*
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
26.7
13.4
18
8
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
23.7
13.0
18
9
T34.4
ICD-10 Finland
Frostbite with tissue necrosis of arm
+∞
12.8
12
*
NDQ20
NOMESCO Finland
Amputation of finger
146.7
12.7
13
*
T36
ICD-10 Finland
Poisoning by systemic antibiotics
19.4
12.2
18
11
NHQ40
NOMESCO Finland
Amputation of toe
34.5
12.0
15
5
X58
ICD-10 Finland
Exposure to other specified factors
5.6
10.6
34
83
T34.9
ICD-10 Finland
Frostbite with tissue necrosis of other and unspecified sites
+∞
10.6
10
*
T33.5
ICD-10 Finland
Superficial frostbite of wrist and hand
+∞
10.6
10
*
X59
ICD-10 Finland
Exposure to unspecified factor
4.8
10.2
38
110
ZZA00
NOMESCO Finland
Split skin graft
17.2
9.9
15
10
T33.8
ICD-10 Finland
Superficial frostbite of ankle and foot
109.4
9.6
10
*
N05AH03
ATC
olanzapine; systemic
8.9
9.5
20
27
N05AA02
ATC
levomepromazine; systemic
14.3
9.2
15
12
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
20.9
9.2
13
7
F10.25
ICD-10 Finland
Alcohol dependence continuous use
30.3
8.7
11
*
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
30.3
8.7
11
*
N05AH04
ATC
quetiapine; oral
4.4
8.4
33
98
P15
ICPC
Chronic alcohol abuse
10.1
7.8
15
17
J01FF01
ATC
clindamycin; systemic
3.6
7.8
41
157
T34.0
ICD-10 Finland
Frostbite with tissue necrosis of head
+∞
7.4
7
*
T34.7
ICD-10 Finland
Frostbite with tissue necrosis of knee and lower leg
+∞
7.4
7
*
QDG20
NOMESCO Finland
Operation for chronic ulcer or fistula of skin of lower limb
42.9
6.9
8
*
F10.39
ICD-10 Finland
Withdrawal symptoms caused by alcohol UNS
24.3
6.8
9
*
S97
ICPC
Chronic ulcer skin
9.7
6.8
13
15
SPAT1148
SPAT
Treatment of chronic ulcer or burn
4.4
6.6
24
66
QCB10
NOMESCO Finland
Major dressing of wound of skin of upper limb
19.4
6.4
9
5
F10.26
ICD-10 Finland
Alcohol dependence periodic alcoholism
28.5
6.3
8
*
NDQ48
NOMESCO Finland
Revision or amputation or exarticulation of finger
+∞
6.3
6
*
X39
ICD-10 Finland
Exposure to other and unspecified forces of nature
+∞
6.3
6
*
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
5.2
6.3
19
43
N05BA04
ATC
oxazepam; oral
3.4
6.0
32
120
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
28
122
2.73
4.58
2.4
2.0
1.88
1.46
%
0.96
23
109
29
151
2.25
3.18
1.8
1.6
953.57
1218.84
nmol/l
1.15
23
118
19
92
2.29
2.44
13.7
13.8
2.27
0.79
mmol/l
1.74
12
75
16
76
2.29
2.15
3.8
4.2
3.21
1.58
mmol/l
—
10
54
24
137
1.96
2.04
1.5
1.8
—
—
—
0
0
12
53
2.42
1.88
1.3
1.6
—
—
—
0
0
10
46
2.29
1.45
1.5
1.3
—
—
—
0
0
17
99
1.85
1.36
1.4
1.7
—
—
—
0
0
23
336
0.60
1.34
3.3
4.2
31.23
22.07
%
1.24
11
151
40
297
1.54
1.32
2.7
1.9
88.27
93.65
pmol/l
0.42
24
146
48
594
0.66
1.31
3.2
3.1
—
—
—
0
0
16
95
1.80
1.21
1.4
1.7
—
—
—
0
0
0
33
0.00
1.18
0.0
2.1
—
—
—
0
0
0
33
0.00
1.18
0.0
2.1
—
3.60
—
0
28
17
255
0.61
1.08
2.5
2.9
0.73
0.75
ug/l
0.04
11
167
69
783
0.69
1.07
4.7
4.0
1.83
1.93
mu/l
0.35
63
707
16
101
1.68
1.00
6.8
6.9
—
—
—
0
0
0
28
0.00
0.99
0.0
2.3
—
0.00
—
0
28
6
27
2.29
0.95
1.5
2.3
—
8231.71
—
0
7
6
28
2.21
0.93
1.8
1.8
—
—
—
0
0
6
29
2.13
0.91
1.3
3.0
—
—
—
0
0
6
29
2.13
0.91
1.8
2.0
—
—
—
0
0
14
89
1.66
0.86
2.4
3.4
—
—
—
0
0
48
396
1.37
0.85
4.4
4.4
—
—
—
0
0
0
24
0.00
0.80
0.0
1.6
—
—
—
0
0
0
24
0.00
0.80
0.0
1.4
—
—
—
0
0
0
24
0.00
0.80
0.0
1.4
—
—
—
0
0
0
24
0.00
0.80
0.0
1.4
—
—
—
0
0
0
25
0.00
0.80
0.0
1.6
—
—
—
0
0
0
26
0.00
0.79
0.0
2.3
—
0.00
—
0
26
0
26
0.00
0.79
0.0
2.3
—
0.00
—
0
26
23
169
1.46
0.78
1.3
1.6
486.61
460.51
pmol/l
0.11
18
150
5
24
2.13
0.75
2.4
2.1
219.40
228.71
%
—
5
24
78
846
0.74
0.69
4.0
3.9
1.34
1.31
mmol/l
0.16
72
775
81
873
0.73
0.68
4.3
4.2
1.32
1.38
mmol/l
0.73
75
802
7
43
1.67
0.68
1.4
1.8
—
—
—
0
0
40
331
1.33
0.67
2.9
3.2
29.10
36.01
ng/l
0.32
25
220
10
63
1.65
0.64
3.5
2.6
90.20
58.36
ml/min/173m2
—
5
25
26
203
1.37
0.63
2.7
2.5
—
—
—
0
0
0
20
0.00
0.61
0.0
1.2
—
—
—
0
0
37
307
1.31
0.61
3.3
3.1
—
—
—
0
0
0
21
0.00
0.60
0.0
1.1
—
—
—
0
0
12
171
0.67
0.60
1.3
1.5
—
—
—
0
0
0
22
0.00
0.60
0.0
1.9
—
—
—
0
0
0
23
0.00
0.59
0.0
1.7
—
—
—
0
0
0
23
0.00
0.59
0.0
1.7
—
—
—
0
0
80
857
0.76
0.57
4.8
4.2
6.06
5.96
mmol/l
0.18
75
780
84
894
0.75
0.57
4.7
4.6
2.63
2.72
mmol/l
0.36
79
821
9
64
1.44
0.53
3.1
2.1
—
—
—
0
0
6
91
0.64
0.44
1.5
1.4
—
—
—
0
0
78
829
0.80
0.43
13.2
12.6
89.49
84.40
ml/min/173m2
0.91
65
682
8
57
1.43
0.43
2.9
1.9
—
—
—
0
0
83
876
0.79
0.43
4.4
4.2
4.37
4.56
mmol/l
0.86
78
808
0
16
0.00
0.41
0.0
1.6
—
—
—
0
0
10
71
1.45
0.41
1.5
2.2
7.22
12.70
ug/l
—
10
63
18
144
1.30
0.38
1.8
2.5
1.19
0.85
e6/l
—
7
82
19
155
1.27
0.35
4.3
3.8
42.71
326.26
ng/l
0.81
14
123
7
55
1.29
0.30
21.9
11.6
0.64
0.73
%
—
7
55
79
828
0.84
0.30
20.3
14.4
39.43
41.25
%
0.64
46
638
7
56
1.27
0.30
22.1
11.5
1.91
1.46
%
—
7
56
53
492
1.15
0.26
8.8
9.9
4.15
4.25
e9/l
0.09
43
431
10
125
0.78
0.24
1.5
2.5
9.88
14.54
umol/l
—
10
118
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.7
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.6
—
—
—
0
0
0
14
0.00
0.20
0.0
3.0
—
—
—
0
0
21
236
0.86
0.19
1.9
3.0
1796.25
1308.75
ng/l
0.15
16
189
15
129
1.19
0.18
1.7
3.1
2.47
2.44
mmol/l
0.47
15
116
60
627
0.91
0.16
3.6
3.4
15.06
14.83
pmol/l
0.30
55
557
11
125
0.87
0.11
2.7
2.2
—
—
—
0
0
5
44
1.14
0.10
3.2
2.7
1.28
1.35
%
—
5
44
18
196
0.90
0.10
1.8
1.6
1.61
1.44
mg/l
0.10
13
147
27
253
1.09
0.09
3.4
4.3
5.74
11.65
mg/mmol
0.86
19
163
31
322
0.95
0.05
4.9
3.2
—
—
—
0
0
26
250
1.05
0.04
2.6
3.0
0.35
0.43
e6/l
0.10
19
189
14
134
1.05
0.00
1.1
1.2
16.00
30.72
iu/ml
—
5
47
89
891
0.99
0.00
19.1
13.4
30.59
23.44
mg/l
1.18
75
695
0
7
0.00
0.00
0.0
1.7
—
10.57
—
0
7
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
1889.20
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
0.31
—
0
6
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
2.8
—
38.80
—
0
5
0
5
0.00
0.00
0.0
7.2
—
200.34
—
0
5
0
7
0.00
0.00
0.0
2.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.9
—
—
—
0
0
11
110
1.00
0.00
2.6
2.0
—
—
—
0
0
0
7
0.00
0.00
0.0
2.3
—
870.57
—
0
7
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
5.9
—
—
—
0
0
0
7
0.00
0.00
0.0
2.1
—
13.39
—
0
7
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: ST19_FROST_W_TISSUE_NECROS – Frostbite with tissue necrosis
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).