info icon

This is a non-core endpoint: only basic statistics are computed.

Frostbite involving multiple body regions and unspecified frostbite

ST19_FROST_INVOLVI_MULTIPLE_BODY_REGIONS_UNSPE_FROST

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 T35
  • Cause of death: ICD-10 T35

2 out of 7 registries used, show all original rules.

84

4. Check minimum number of events

None

84

5. Include endpoints

None

84

6. Filter based on genotype QC (FinnGen only)

83

Control definitions (FinnGen only)

Control exclude
ST19_FROSTBITE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
T3[3-5]
Name in latin
Congelatio multarum regionum corporis sive non specificata

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 83 24 59
Unadjusted period prevalence (%) 0.02 0.01 0.03
Median age at first event (years) 54.50 59.13 52.61

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
84
Matched controls
840
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
X31
ICD-10 Finland
Exposure to excessive natural cold
+∞
43.6
38
*
T35.5
ICD-10 Finland
Unspecified frostbite of lower limb
+∞
34.8
31
*
T35.4
ICD-10 Finland
Unspecified frostbite of upper limb
+∞
30.0
27
*
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
9.7
18.6
26
37
T68
ICD-10 Finland
Hypothermia
194.8
16.1
16
*
T35.0
ICD-10 Finland
Superficial frostbite involving multiple body regions
+∞
13.9
13
*
X59
ICD-10 Finland
Exposure to unspecified factor
4.5
9.9
34
110
AA1AD
NOMESCO Finland
CT of head and brain
4.1
9.1
38
141
T33.5
ICD-10 Finland
Superficial frostbite of wrist and hand
+∞
8.5
8
*
SPAT1148
SPAT
Treatment of chronic ulcer or burn
4.7
8.3
23
62
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
4.3
7.9
26
80
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
9.9
7.7
15
18
NDQ20
NOMESCO Finland
Amputation of finger
87.5
7.5
8
*
G72.8
ICD-10 Finland
Other specified myopathies
17.8
7.5
11
7
N07BB01
ATC
disulfiram; oral
8.3
7.4
16
23
F10.49
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without information about seizures
+∞
7.4
7
*
X58
ICD-10 Finland
Exposure to other specified factors
4.1
7.2
24
74
ZZA00
NOMESCO Finland
Split skin graft
19.9
6.4
9
5
N05AH04
ATC
quetiapine; oral
3.6
6.4
27
98
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
3.2
6.4
38
171
L28
ICPC
Limited function/disability (L)
4.1
6.3
20
59
T34.5
ICD-10 Finland
Frostbite with tissue necrosis of wrist and hand
+∞
6.3
6
*
T35.3
ICD-10 Finland
Unspecified frostbite of thorax, abdomen, lower back and pelvis
+∞
6.3
6
*
T35.7
ICD-10 Finland
Unspecified frostbite of unspecified site
+∞
6.3
6
*
A46
ICD-10 Finland
Erysipelas
3.9
6.1
21
66

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
44
191
3.74
8.22
4.0
2.3
1118.27
281.79
u/l
0.61
44
180
25
74
4.39
8.01
2.4
1.4
—
—
—
0
0
36
169
2.98
5.47
5.6
4.1
—
—
—
0
0
14
41
3.90
4.40
7.1
7.0
24.71
24.29
mmol/l
0.15
14
41
13
31
4.76
4.23
11.2
12.4
24.43
24.64
mmol/l
0.10
13
31
40
224
2.50
4.06
5.5
4.0
913.24
35.99
ng/l
0.49
33
152
49
303
2.48
4.00
11.2
11.5
1.28
1.26
inr
0.06
18
82
31
158
2.52
3.80
3.6
3.0
—
—
—
0
0
30
153
2.49
3.66
5.6
3.5
0.00
0.00
estimate
-0.00
13
54
18
71
2.95
3.58
11.4
9.2
104.28
103.82
mmol/l
0.12
18
71
22
98
2.69
3.51
2.3
2.0
31.05
29.39
s
0.48
22
98
8
14
6.19
3.43
2.9
2.8
—
—
—
0
0
14
49
3.23
3.38
11.0
8.8
—
—
—
0
0
45
288
2.21
3.16
5.2
4.6
0.00
0.00
estimate
-0.00
14
58
44
285
2.14
2.93
10.8
9.2
1.18
1.21
mmol/l
1.36
37
248
45
296
2.12
2.86
4.5
3.3
0.00
0.00
estimate
-0.00
13
55
12
41
3.24
2.76
4.3
17.2
—
—
—
0
0
13
50
2.89
2.68
3.3
3.4
—
—
—
0
0
8
20
4.30
2.64
7.0
6.3
—
—
—
0
0
44
294
2.04
2.62
4.6
3.3
0.00
0.00
estimate
-0.00
13
60
9
27
3.61
2.47
3.6
1.3
—
—
—
0
0
6
13
4.88
2.31
2.0
1.4
—
—
—
0
0
9
29
3.35
2.30
3.6
1.3
—
—
—
0
0
9
29
3.35
2.30
3.6
1.3
—
—
—
0
0
9
29
3.35
2.30
3.6
1.3
—
—
—
0
0
10
35
3.10
2.30
13.8
24.9
—
—
—
0
0
17
82
2.35
2.26
3.4
2.3
—
—
—
0
0
51
372
1.94
2.25
10.5
10.6
4.98
4.01
e9/l
1.03
43
325
9
32
3.02
2.07
4.6
4.6
139.33
123.66
g/l
—
9
32
7
21
3.54
2.01
3.4
1.2
—
—
—
0
0
29
181
1.92
1.99
5.6
4.0
7.40
7.40
ph
—
7
34
29
182
1.91
1.96
3.0
2.4
—
—
—
0
0
7
22
3.37
1.92
5.3
1.3
—
—
—
0
0
8
28
3.05
1.92
3.9
1.3
—
—
—
0
0
5
12
4.36
1.85
5.0
2.3
—
—
—
0
0
32
211
1.83
1.84
3.0
2.4
100.71
357.23
e6/l
0.38
27
163
12
55
2.38
1.77
1.3
1.7
—
—
—
0
0
35
244
1.74
1.64
3.1
2.8
759.39
25.25
e6/l
0.74
27
170
25
158
1.83
1.62
4.0
3.0
—
—
—
0
0
6
20
3.15
1.61
2.5
1.3
—
—
—
0
0
40
291
1.72
1.61
5.3
7.0
—
—
—
0
0
53
418
1.73
1.57
4.3
3.9
—
—
—
0
0
28
187
1.75
1.51
2.7
2.5
—
—
—
0
0
7
28
2.63
1.48
5.6
4.6
25.37
24.50
mmol/l
—
7
28
41
306
1.66
1.46
4.7
6.6
0.04
0.04
e9/l
0.08
35
272
41
307
1.66
1.44
4.7
6.6
0.66
0.58
e9/l
1.01
34
272
0
37
0.00
1.38
0.0
1.0
—
—
—
0
0
5
17
3.06
1.38
4.0
2.3
4.82
5.26
kpa
—
5
17
5
17
3.06
1.38
4.0
2.3
8.94
8.61
kpa
—
5
17
23
149
1.75
1.36
3.4
7.6
—
—
—
0
0
28
192
1.69
1.36
3.1
2.3
0.14
0.30
e6/l
0.81
23
145
22
141
1.76
1.35
4.5
3.3
—
—
—
0
0
38
285
1.61
1.29
16.1
9.8
0.00
0.00
e9/l
0.50
31
235
26
179
1.66
1.23
3.7
3.1
8.30
7.96
mmol/l
0.12
20
159
0
33
0.00
1.19
0.0
1.5
—
—
—
0
0
15
234
0.56
1.18
2.1
1.9
—
—
—
0
0
7
32
2.29
1.11
7.1
1.7
—
—
—
0
0
54
454
1.53
1.03
4.8
3.8
—
—
—
0
0
6
27
2.31
0.95
3.5
2.5
1.28
1.37
%
—
6
27
6
27
2.31
0.95
3.5
2.5
0.67
0.73
%
—
6
27
27
199
1.53
0.95
2.2
3.5
2.31
2.35
mmol/l
0.68
22
178
73
670
1.68
0.81
25.7
13.0
23.61
24.26
mg/l
0.07
62
521
0
24
0.00
0.80
0.0
1.4
—
0.25
—
0
24
0
25
0.00
0.80
0.0
1.4
—
1.20
—
0
25
69
626
1.57
0.80
4.6
4.2
5.88
5.95
mmol/l
0.21
60
580
0
26
0.00
0.80
0.0
1.6
—
—
—
0
0
15
100
1.61
0.79
1.9
1.7
—
—
—
0
0
15
100
1.61
0.79
2.1
2.8
2.45
2.46
mmol/l
—
9
83
5
23
2.25
0.77
2.0
3.1
—
—
—
0
0
22
164
1.46
0.72
2.0
3.2
14.57
76.30
mg/l
2.28
12
114
75
700
1.67
0.67
26.5
12.1
—
—
—
0
0
11
71
1.63
0.66
1.5
1.8
—
—
—
0
0
19
248
0.70
0.64
2.4
2.6
—
—
—
0
0
8
51
1.63
0.62
1.1
1.3
—
—
—
0
0
13
89
1.55
0.62
1.8
1.7
—
—
—
0
0
8
53
1.56
0.60
1.3
1.5
—
—
—
0
0
0
22
0.00
0.60
0.0
12.5
—
—
—
0
0
22
173
1.37
0.54
2.5
3.8
2.49
12.77
mg/mmol
2.44
11
113
7
47
1.53
0.49
2.9
3.2
—
—
—
0
0
8
56
1.47
0.44
1.5
1.7
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.7
—
—
—
0
0
21
171
1.30
0.41
4.0
3.9
—
—
—
0
0
62
577
1.28
0.40
29.3
16.2
14.25
14.54
%
0.29
62
570
6
89
0.65
0.35
1.0
1.3
—
—
—
0
0
71
677
1.31
0.33
30.3
15.6
4.00
3.98
mmol/l
0.18
71
663
25
214
1.24
0.33
2.1
2.0
88.63
98.43
pmol/l
0.49
15
102
9
73
1.26
0.26
1.3
1.4
—
—
—
0
0
70
672
1.25
0.25
30.6
15.6
139.19
139.65
mmol/l
0.63
70
659
55
580
0.85
0.23
4.2
4.3
1.94
1.89
mu/l
0.10
48
532
5
39
1.30
0.23
1.8
2.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
22
194
1.18
0.21
1.4
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
205.31
—
0
12
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
6.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.9
—
5.46
—
0
5
5
65
0.75
0.17
4.4
4.0
2.28
79.12
ug/l
—
5
52
5
43
1.17
0.10
1.2
3.6
—
—
—
0
0
5
47
1.07
0.09
2.4
1.7
28.40
38.23
nmol/l
—
5
47
66
674
0.90
0.08
4.4
4.6
2.64
2.79
mmol/l
0.57
61
623
15
163
0.90
0.07
1.5
2.7
372.13
4401.71
umol/l
0.78
15
137
76
750
1.14
0.07
37.7
19.3
39.31
41.33
%
1.80
71
706
65
659
0.94
0.03
3.9
4.2
4.50
4.62
mmol/l
0.38
60
617
65
657
0.95
0.01
3.6
4.2
1.39
1.37
mmol/l
0.11
60
609
64
639
1.01
0.00
3.3
3.8
1.35
1.35
mmol/l
0.03
59
595
47
466
1.02
0.00
3.7
3.6
14.83
15.01
pmol/l
0.21
42
420
0
6
0.00
-0.00
0.0
1.2
—
140.50
—
0
6
13
130
1.00
-0.00
2.2
2.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
60
1.00
-0.00
1.5
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
5.4
—
8.74
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.3
—
—
—
0
0
5
50
1.00
-0.00
1.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
7
71
0.98
-0.00
1.9
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
74
0.94
-0.00
1.1
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
73.40
—
0
5
6
64
0.93
-0.00
4.2
1.5
434.17
398.63
nmol/l
—
6
57
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.7
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
3.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
3.1
—
106.22
—
0
9
0
9
0.00
-0.00
0.0
4.8
—
—
—
0
0
0
9
0.00
-0.00
0.0
3.1
—
4.11
—
0
9

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: ST19_FROST_INVOLVI_MULTIPLE_BODY_REGIONS_UNSPE_FROST – Frostbite involving multiple body regions and unspecified frostbite

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).