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This is a non-core endpoint: only basic statistics are computed.

See its core counterpart C3_CERVIX_ADENO_EXALLC for full statistics.

Adenocarcinomas of cervix

C3_CERVIX_ADENO

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

only females

293373

2. Check conditions

None

293373

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cancer registry: Topography ICD-O-3 C53
  • Cancer registry: Morphology ICD-O-3 8140
  • Cancer registry: Behaviour codes 3

1 out of 7 registries used, show all original rules.

150

4. Check minimum number of events

None

150

5. Include endpoints

None

150

6. Filter based on genotype QC (FinnGen only)

150

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF8

Similar endpoints

List of similar endpoints to Adenocarcinomas of cervix based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 150 150 -
Unadjusted period prevalence (%) 0.05 0.05 -
Median age at first event (years) 42.97 42.97 -

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
154
Matched controls
1540
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
C53.02
ICD-10 Finland
Adenocarcinoma of the endocervix
+∞
135.0
109
*
8140/3-C53.9
ICD-O-3
Adenocarcinoma, NOS, of cervix uteri
+∞
112.8
94
*
8140/3-C53.0
ICD-O-3
Adenocarcinoma, NOS, of endocervix
+∞
54.5
49
*
LDC03
NOMESCO Finland
Conisation of cervix uteri using diathermy or laser
24.0
49.1
74
57
128
Kela drug reimbursment
Cancers of female genital organs
72.3
47.7
53
11
ULA02
NOMESCO Finland
Kolposcopy
15.0
47.4
96
153
C53.12
ICD-10 Finland
Adenocarcinoma of the exocervix
+∞
40.4
37
*
PJD64
NOMESCO Finland
Laparoscopic dissection of iliac lymph nodes
129.5
37.7
39
*
LCD31
NOMESCO Finland
Radical laparoscopic hysterectomy
241.3
37.6
37
*
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
10.9
37.5
88
167
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
9.3
31.8
80
160
ZXC96
NOMESCO Finland
Robot assisted procedure
96.1
29.0
31
*
LEB00
NOMESCO Finland
Biopsy of vagina
30.0
27.7
37
16
PJA01
NOMESCO Finland
Laparoscopic sentinel node excision
88.5
26.8
29
*
LDA20
NOMESCO Finland
Biopsy of vaginal cervix
9.3
25.6
59
96
JN2DG
NOMESCO Finland
Very extensive MRI examination of lower part of abdoment with high intensity magnet
46.3
22.6
27
7
LCD30
NOMESCO Finland
Radical hysterectomy
254.7
22.2
22
*
WF002
NOMESCO Finland
Radical radiotherapy
26.9
19.9
27
12
D06.0
ICD-10 Finland
Carcinoma in situ: Endocervix
53.6
19.8
23
5
TLW99
NOMESCO Finland
Other minor surgical procedure in gynaecology
22.5
19.5
28
15
JN4KR
NOMESCO Finland
Whole body very extensive metabolic PET with CT
76.0
18.2
20
*
PJ5AQ
NOMESCO Finland
Sentinell lymphnode SPECT with low dose CT
76.0
18.2
20
*
C53.00
ICD-10 Finland
Malignant tumor of endocervix without histology
+∞
18.1
17
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
13.2
18.0
32
30
LDA10
NOMESCO Finland
Curettage of cervix uteri
8.9
18.0
40
58
B01AB10
ATC
tinzaparin; parenteral
9.5
17.8
38
51
YL1BD
NOMESCO Finland
Extensive CT examination of pelvis for dose design of radiotherapy
57.0
17.5
20
*
JN2CG
NOMESCO Finland
Extensive MRI examination of lower part of abdoment with high intensity magnet
26.7
17.0
23
10
LX1XE
NOMESCO Finland
Other gynecological ultrasound examination
14.6
16.7
28
23
121
Kela drug reimbursment
Severe hypofunction of sexual glands
17.1
16.6
26
18
LAF11
NOMESCO Finland
Laparoscopic bilateral salpingo-oophorectomy
9.6
16.2
34
44
C53.0
ICD-10 Finland
Malignant neoplasm: Endocervix
+∞
15.9
15
*
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
10.4
15.1
30
35
C53.01
ICD-10 Finland
Squamous cell carcinoma of the endocervix
165.0
14.7
15
*
ZX095
NOMESCO Finland
Combined chemoradiotherapy
82.3
13.8
15
*
A03FA01
ATC
metoclopramide; systemic, rectal
4.2
13.6
64
225
H02AB02
ATC
dexamethasone; systemic
5.8
12.9
39
85
ZX020
NOMESCO Finland
HDR radiotherapy within tissue
+∞
12.7
12
*
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
3.6
12.6
82
371
B01AB05
ATC
enoxaparin; parenteral
3.7
12.5
73
304
YJ2VG
NOMESCO Finland
MRI examination of pelvis with high intensity magnet for dose design of radiotherapy
51.0
12.1
14
*
PJD54
NOMESCO Finland
Block dissection of iliac lymph nodes
51.0
12.1
14
*
C53.09
ICD-10 Finland
Malignant tumor of endocervix, unspecified histology
+∞
11.6
11
*
8140/3-C53.1
ICD-O-3
Adenocarcinoma, NOS, of exocervix
+∞
11.6
11
*
XX3DW
NOMESCO Finland
Time consuming IT work
5.3
11.3
36
83
LCA06
NOMESCO Finland
Biopsy of endometrium
4.3
11.1
46
140
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
4.1
10.9
48
154
N13.3
ICD-10 Finland
Other and unspecified hydronephrosis
17.7
10.6
16
10
ZX040
NOMESCO Finland
Intracavity HDR radiotherapy
58.8
9.8
11
*
ZX070
NOMESCO Finland
Intensity modified radiotherapy
19.1
9.6
14
8
ZXE30
NOMESCO Finland
More than five and less than seven hours
10.6
9.6
18
19
1800A
ICD-9 Finland
Malignant neoplasm of cervix uteri, Endocervix
+∞
9.5
9
*
C53
ICD-10 Finland
Malignant neoplasm of cervix uteri
+∞
9.5
9
*
C53.92
ICD-10 Finland
Adenocarcinoma in an unspecified location in the cervix
+∞
9.5
9
*
JN4BD
NOMESCO Finland
Extensive body CT
4.5
9.2
34
91
UKC02
NOMESCO Finland
Cystoscopy
4.7
8.9
31
78
A04AA55
ATC
palonosetron, combinations; systemic
7.2
8.9
21
33
LBE10
NOMESCO Finland
Bilateral salpingectomy
+∞
8.4
8
*
I89.0
ICD-10 Finland
Lymphoedema, not elsewhere classified
47.4
7.8
9
*
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
19.6
7.7
11
6
KBV02
NOMESCO Finland
Cystoscopic insertion of stent into ureter
10.9
7.7
14
14
A04AA01
ATC
ondansetron; systemic, rectal
4.7
7.7
26
64
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
2.6
7.6
80
449
8310
FHL
Radical hysterectomy (includes lymph node removal)
84.0
7.5
8
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
8.0
7.4
16
22
C53.90
ICD-10 Finland
Malignant tumor in unspecified localization in cervix uteri without histology
+∞
7.3
7
*
C53.99
ICD-10 Finland
Malignant tumor in unspecified localization in cervix, unspecified histology
+∞
7.3
7
*
ZXE20
NOMESCO Finland
More than three and less than five hours
3.9
7.3
30
89
C53.11
ICD-10 Finland
Squamous cell carcinoma and exocervix
31.6
7.2
9
*
P01AB01
ATC
metronidazole; oral, rectal
2.5
7.1
85
507
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
8.9
7.0
14
17
KBV12
NOMESCO Finland
Transluminal endoscopic removal of stent from ureter
23.7
6.8
9
*
8077/2-C53.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of cervix uteri
8.0
6.6
14
19
KBV00
NOMESCO Finland
Insertion of stent into ureter
72.7
6.5
7
*
YX9VG
NOMESCO Finland
Other MRI eamination with high intensity magnet for dose design of radiotherapy
72.7
6.5
7
*
WX402
NOMESCO Finland
General anaesthesia
3.0
6.5
39
154
A04AA02
ATC
granisetron; systemic, transdermal
5.1
6.4
19
41
JN2BG
NOMESCO Finland
MRI examination of lower part of abdoment with high intensity magnet
19.0
6.3
9
5
C53.9
ICD-10 Finland
Malignant neoplasm: Cervix uteri, unspecified
+∞
6.3
6
*
C53.1
ICD-10 Finland
Malignant neoplasm: Exocervix
+∞
6.3
6
*
PJ5AN
NOMESCO Finland
Localisation of sentinell lymphnode with isotope imaging
9.2
6.2
12
14

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: C3_CERVIX_ADENO – Adenocarcinomas of cervix

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).