No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
|
1. Apply sex-specific ruleNone |
- |
2. Check conditionsNone |
|
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
- |
4. Check minimum number of eventsNone |
- |
5. Include endpointsNone |
- |
6. Filter based on genotype QC (FinnGen only)None |
- |
Control definitions (FinnGen only)
- Control exclude
- G6_AD_WIDE, F5_DEMENTIA, F5_DEMENTIA_U, F5_PSYCH, NEURODIS, MEMLOSS, TRAUMBRAIN_NONCONCUS
Extra metadata
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Alzheimer’s disease (Early onset), excluding more controls
based on the number of shared cases.
Similar with more cases:
- Alzheimer’s disease (Early onset)
- Alzheimer’s disease, wide definition, excluding more controls
- Alzheimer’s disease, wide definition
- Unspecific neurodegenerative disorder
- Any dementia, excluding more controls
Similar with less cases:
Case counts by codes
↥FinnGen case counts by registry codes:
No upset plot: script not run.
No upset table: script not run.
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 33683 | 20929 | 12434 |
| Only index persons | 27051 | 17263 | 9788 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.50 | 0.60 | 0.35 |
| Only index persons | 0.54 | 0.63 | 0.37 |
| Median age at first event (years) | |||
| Whole population | 80.07 | 81.15 | 78.31 |
| Only index persons | 80.19 | 81.30 | 78.22 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1879 | 914 | 965 |
| Unadjusted period prevalence (%) | 0.37 | 0.31 | 0.43 |
| Median age at first event (years) | 76.41 | 74.94 | 77.80 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1565
- Matched controls
- 15165
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G30.0
ICD-10 Finland
Alzheimer disease with early onset
+∞
323.0
892
*
N06DX01
ATC
memantine; oral
855.1
323.0
885
23
N06DA03
ATC
rivastigmine; oral, transdermal
1433.6
323.0
504
5
F03
ICD-10 Finland
Unspecified dementia
109.1
323.0
370
43
307
Kela drug reimbursment
Tacrine, donepezil, rivastigmine, galantamine and other major and expensive drugs used to treat Alzheimer's disease
+∞
323.0
941
*
G30.9
ICD-10 Finland
Alzheimer disease, unspecified
2565.0
323.0
633
*
N06DA02
ATC
donepezil; oral
979.8
323.0
832
17
F00.10*G30.1
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset without additional symptoms
382.9
323.0
387
13
N05AX08
ATC
risperidone; systemic
98.5
323.0
496
71
G30.1
ICD-10 Finland
Alzheimer disease with late onset
359.4
323.0
722
36
F00.00*G30.0
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset without additional symptoms
+∞
323.0
528
*
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
24.3
300.2
445
244
N05AH04
ATC
quetiapine; oral
23.5
280.8
420
233
F0009, G300
ICD-10 Finland
NA
+∞
229.4
217
*
P20
ICPC
Memory disturbance
10.4
228.6
502
661
N06DA04
ATC
galantamine; oral
406.3
220.6
219
6
G30
ICD-10 Finland
Alzheimer disease
2229.6
197.9
190
*
F00.00
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset without additional symptoms
+∞
196.9
187
*
F00.10
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset without additional symptoms
2059.3
186.1
179
*
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
202.9
178.9
185
10
P70
ICPC
Dementia
65.7
159.5
186
31
G30.8
ICD-10 Finland
Other Alzheimer disease
150.7
157.7
167
12
TAB00
NOMESCO Finland
Lumbar puncture
44.4
155.1
194
48
F0019, G301
ICD-10 Finland
NA
+∞
148.7
142
*
N03AG01
ATC
valproic acid; systemic, rectal
112.1
134.9
147
14
XA800
NOMESCO Finland
Neuropsychological investigation
242.1
133.6
137
6
F009, G309
ICD-10 Finland
NA
+∞
116.8
112
*
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
113.3
109.2
119
11
AA1AD
NOMESCO Finland
CT of head and brain
5.4
109.2
375
838
N05BA04
ATC
oxazepam; oral
4.4
108.2
477
1384
F06.7
ICD-10 Finland
Mild cognitive disorder
35.6
105.3
138
41
SPAT1053
SPAT
Memory test
4.7
103.8
414
1081
N06AB04
ATC
citalopram; systemic
5.0
103.4
378
900
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
+∞
102.0
98
*
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
+∞
102.0
98
*
S06.0
ICD-10 Finland
Concussion
29.2
100.3
138
50
N06AX11
ATC
mirtazapine; oral
3.9
98.2
489
1565
N06AB10
ATC
escitalopram; oral
6.3
96.3
283
516
R53
ICD-10 Finland
Malaise and fatigue
4.3
94.6
417
1188
F00.20*G30.8
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type without additional symptoms
82.1
91.1
103
13
N05AH03
ATC
olanzapine; systemic
88.0
91.0
102
12
F32.9
ICD-10 Finland
Depressive episode, unspecified
21.6
88.4
133
65
R41.3
ICD-10 Finland
Other amnesia
36.8
87.0
113
32
F00.9
ICD-10 Finland
Dementia in Alzheimer disease, unspecified
868.4
86.5
85
*
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
42.0
86.3
109
27
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
11.9
85.3
163
146
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
3.2
82.2
570
2308
SPAT1245
SPAT
Provision of support and information to patient’s family members
8.2
76.7
181
237
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
12.2
72.8
137
118
G40.9
ICD-10 Finland
Epilepsy, unspecified
707.5
70.8
70
*
A28
ICPC
Limited function/disability NOS
3.4
68.2
391
1345
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.6
66.9
357
1159
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.8
66.7
596
2764
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
7.0
65.2
171
261
S06.5
ICD-10 Finland
Traumatic subdural haemorrhage
623.0
62.5
62
*
G47.3
ICD-10 Finland
Sleep apnoea
14.9
60.7
104
72
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
11.0
59.4
117
110
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.6
57.6
300
944
Z2445
NOMESCO Finland
Psychologist
105.9
57.5
63
6
Z75.5
ICD-10 Finland
Holiday relief care
31.3
57.3
77
25
G91.2
ICD-10 Finland
Normal-pressure hydrocephalus
570.6
57.3
57
*
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
4.9
55.6
198
438
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
+∞
54.9
53
*
SPAT1216
SPAT
Assessment of functional ability
3.3
54.5
325
1130
N05BA06
ATC
lorazepam; systemic, sublingual
6.7
54.1
145
227
R56.8
ICD-10 Finland
Other and unspecified convulsions
13.9
54.0
95
70
R41.0
ICD-10 Finland
Disorientation, unspecified
13.1
53.7
97
76
SPAT1234
SPAT
Support of social functional capacity
6.2
52.7
150
254
N05AD01
ATC
haloperidol; systemic
8.5
52.1
119
146
G20
ICD-10 Finland
Parkinson disease
137.9
51.5
55
*
N04BA02
ATC
levodopa and decarboxylase inhibitor; oral
26.6
50.8
71
27
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
7.2
50.2
128
186
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
4.1
49.8
212
557
A06AD11
ATC
lactulose; oral
2.8
48.2
374
1537
F05.1
ICD-10 Finland
Delirium superimposed on dementia
+∞
47.6
46
*
WYA20
NOMESCO Finland
Home visit
20.8
43.9
66
32
F05.9
ICD-10 Finland
Delirium, unspecified
71.2
43.6
50
7
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
3.0
43.4
282
1026
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
219.0
42.6
44
*
110
Kela drug reimbursment
Parkinson's disease and comparable movement disrorders
+∞
42.4
41
*
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
3.0
41.9
281
1042
L28
ICPC
Limited function/disability (L)
2.8
40.7
302
1194
G56.0
ICD-10 Finland
Carpal tunnel syndrome
9.7
39.8
83
87
SPAT1254
SPAT
Administration of medicine
2.9
39.6
276
1048
F00.20
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type without additional symptoms
203.7
39.5
41
*
N05AD03
ATC
melperone; systemic
17.8
39.2
62
35
N06AB06
ATC
sertraline; oral
5.9
37.5
110
193
F00.09
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset information on additional symptoms is lacking
+∞
37.2
36
*
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
81.6
36.5
41
5
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
+∞
36.2
35
*
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
47.5
35.3
43
9
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.6
34.2
278
1148
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
23.9
33.6
48
20
R55
ICD-10 Finland
Syncope and collapse
3.0
33.0
209
738
F00.01
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset other additional symptoms, mainly paranoidism
+∞
32.0
31
*
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
+∞
32.0
31
*
N02BE01
ATC
paracetamol; systemic, rectal
2.0
31.6
1153
8884
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
19.1
31.3
48
25
F00
ICD-10 Finland
Dementia in Alzheimer disease
+∞
31.0
30
*
AAD10
NOMESCO Finland
Evacuation of chronic subdural haematoma
+∞
31.0
30
*
N06AX16
ATC
venlafaxine; oral
4.9
30.8
104
215
G45.0
ICD-10 Finland
Vertebro-basilar artery syndrome
298.3
29.5
30
*
R42
ICD-10 Finland
Dizziness and giddiness
2.3
29.4
308
1446
G31.0
ICD-10 Finland
Circumscribed brain atrophy
+∞
28.9
28
*
N05CD07
ATC
temazepam; oral
2.4
28.6
266
1173
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
+∞
27.9
27
*
SPAT1251
SPAT
Organisation of medication
4.8
27.8
96
203
G45.1
ICD-10 Finland
Carotid artery syndrome (hemispheric)
143.0
27.3
29
*
N07AA05
ATC
NA
+∞
26.8
26
*
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
8.6
26.7
59
69
130
Kela drug reimbursment
Malignant tumour
0.2
26.5
22
1157
Z02.4
ICD-10 Finland
Examination for driving licence
0.4
26.5
89
2227
F01.9
ICD-10 Finland
Vascular dementia, unspecified
28.8
25.9
35
12
J01CA08
ATC
pivmecillinam; oral
1.9
25.9
529
3246
I63.4
ICD-10 Finland
Cerebral infarction due to embolism of cerebral arteries
+∞
25.8
25
*
N06AX26
ATC
vortioxetine; oral
10.4
25.3
50
48
SPAT1229
SPAT
Assessment of need for aid
3.1
24.8
142
467
F0014, G301
ICD-10 Finland
NA
+∞
24.8
24
*
F00.1
ICD-10 Finland
Dementia in Alzheimer disease with late onset
+∞
24.8
24
*
F22.0
ICD-10 Finland
Delusional disorder
127.9
24.3
26
*
F29
ICD-10 Finland
Unspecified nonorganic psychosis
127.9
24.3
26
*
W19
ICD-10 Finland
Unspecified fall
3.1
24.3
139
456
S72.0
ICD-10 Finland
Fracture of neck of femur
3.4
24.2
123
370
ACC51
NOMESCO Finland
Release of median nerve
47.6
24.0
29
6
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
3.6
23.9
114
326
85000
ICD-8 Finland
Concussion, Current or unspecified
+∞
23.7
23
*
F0029, G308
ICD-10 Finland
NA
+∞
23.7
23
*
N03AF01
ATC
carbamazepine; oral, rectal
5.5
23.6
71
129
N03AX14
ATC
levetiracetam; systemic
37.0
23.6
30
8
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.4
23.4
216
942
F001, G301
ICD-10 Finland
NA
+∞
22.7
22
*
N06AX21
ATC
duloxetine; oral
4.0
22.6
94
239
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
7.4
22.4
54
73
N03AF02
ATC
oxcarbazepine; oral
25.5
22.3
31
12
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.4
22.2
197
843
F0004, G300
ICD-10 Finland
NA
+∞
21.7
21
*
N05AB03
ATC
perphenazine; systemic, rectal
15.7
21.5
35
22
I61.9
ICD-10 Finland
Intracerebral haemorrhage, unspecified
+∞
20.6
20
*
G40.2
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
+∞
20.6
20
*
N05AN01
ATC
lithium; oral
75.4
20.4
23
*
F00.19
ICD-10 Finland
Dementia in Alzheimer's disease with late onset without information about additional symptoms
206.0
20.4
21
*
N06AB03
ATC
fluoxetine; oral
3.1
20.3
120
400
G72.8
ICD-10 Finland
Other specified myopathies
108.0
20.3
22
*
N05CF01
ATC
zopiclone; oral
1.8
20.1
490
3128
S70.0
ICD-10 Finland
Contusion of hip
4.4
20.0
73
165
A04
ICPC
Weakness/tiredness general
2.4
19.9
182
789
N05BA01
ATC
diazepam; systemic, rectal
2.4
19.8
183
797
N02AA05
ATC
oxycodone; systemic
2.0
19.7
269
1399
E86
ICD-10 Finland
Volume depletion
5.1
19.6
63
124
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
+∞
19.6
19
*
F00.0
ICD-10 Finland
Dementia in Alzheimer disease with early onset
+∞
19.6
19
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
5.0
19.5
64
129
T36
ICD-10 Finland
Poisoning by systemic antibiotics
11.5
19.4
36
31
N04AA02
ATC
biperiden; systemic
45.1
18.9
23
5
N05AA02
ATC
levomepromazine; systemic
6.0
18.8
52
86
N03AE01
ATC
clonazepam; systemic
5.1
18.6
59
115
F00.14
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset other additional symptoms of mixed type
+∞
18.6
18
*
SAB01
NOMESCO Finland
Restricted oral and dental health check by dental hygienist or dental assistant
3.2
18.6
100
315
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
68.5
18.5
21
*
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
2.0
18.3
253
1319
J01EA01
ATC
trimethoprim; systemic
1.8
18.1
388
2369
S06.3
ICD-10 Finland
Focal brain injury
+∞
17.5
17
*
N05AH02
ATC
clozapine; systemic
+∞
17.5
17
*
G31.8
ICD-10 Finland
Other specified degenerative diseases of nervous system
+∞
17.5
17
*
I62.0
ICD-10 Finland
Nontraumatic subdural haemorrhage
+∞
17.5
17
*
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
+∞
17.5
17
*
AA5DR
NOMESCO Finland
Brain metabolism PET with CT
+∞
17.5
17
*
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
65.3
17.5
20
*
S01.0
ICD-10 Finland
Open wound of scalp
3.0
17.5
102
340
N28
ICPC
Limited function/disability (N)
17.7
17.5
27
15
I95.1
ICD-10 Finland
Orthostatic hypotension
4.0
17.2
69
171
NFB20
NOMESCO Finland
Primary partial prosthetic replacement of hip joint using cement, other or unspecified
3.7
17.1
77
211
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
12.9
17.1
30
23
K90
ICPC
Stroke/cerebrovascular accident
17.0
16.6
26
15
F02.39*G20
ICD-10 Finland
Dementia in Parkinson's disease without information on additional symptoms
+∞
16.5
16
*
I67.1
ICD-10 Finland
Cerebral aneurysm, nonruptured
+∞
16.5
16
*
3472A
ICD-9 Finland
Cataplexy and narcolepsy[OBSTRUKTIIVINEN UNIAPNEA]
+∞
16.5
16
*
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
+∞
16.5
16
*
F000, G300
ICD-10 Finland
NA
+∞
16.5
16
*
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.0
16.5
232
1217
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.1
16.4
197
966
N03AX09
ATC
lamotrigine; oral
17.5
16.2
25
14
R1250
NOMESCO Finland
Evaluation of functional capability
8.4
16.1
35
41
J01DB01
ATC
cefalexin; oral
1.6
15.9
974
7774
A10AE04
ATC
insulin glargine; parenteral
2.5
15.9
127
513
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
58.7
15.6
18
*
S06.2
ICD-10 Finland
Diffuse brain injury
+∞
15.5
15
*
F00.04
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset other additional symptoms of mixed type
+∞
15.5
15
*
I60.9
ICD-10 Finland
Subarachnoid haemorrhage, unspecified
+∞
15.5
15
*
E000001
ATC
NA
1.9
15.3
252
1399
I64
ICD-10 Finland
Stroke, not specified as haemorrhage or infarction
156.4
15.3
16
*
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
2.2
15.3
172
819
N30.0
ICD-10 Finland
Acute cystitis
2.1
15.3
185
911
SPAT1301
SPAT
No procedures
1.7
15.1
401
2588
SPAT1252
SPAT
Overall medication plan or its review
2.7
15.0
107
402
L89
ICD-10 Finland
Decubitus ulcer and pressure area
5.9
14.7
41
69
SPAT1360
SPAT
Extensive global examination
2.7
14.7
105
397
-
ICD-10 Finland
NA
4.9
14.6
48
98
Z13.3
ICD-10 Finland
Special screening examination for mental and behavioural disorders
55.4
14.6
17
*
R11
ICD-10 Finland
Nausea and vomiting
2.7
14.6
105
400
H02AB02
ATC
dexamethasone; systemic
0.3
14.6
29
938
SPAT1172
SPAT
Guidance concerning hydration
3.8
14.5
61
159
F0001, G300
ICD-10 Finland
NA
+∞
14.4
14
*
LAITO
NOMESCO Finland
NA
+∞
14.4
14
*
I69.0
ICD-10 Finland
Sequelae of subarachnoid haemorrhage
+∞
14.4
14
*
F0009, G309
ICD-10 Finland
NA
+∞
14.4
14
*
I61.0
ICD-10 Finland
Intracerebral haemorrhage in hemisphere, subcortical
+∞
14.4
14
*
G31.9
ICD-10 Finland
Degenerative disease of nervous system, unspecified
+∞
14.4
14
*
N05AX12
ATC
aripiprazole; systemic
+∞
14.4
14
*
R51.80
ICD-10 Finland
Headache
2.8
14.4
93
332
N04BD01
ATC
selegiline; oral
78.3
14.4
16
*
F05.8
ICD-10 Finland
Other delirium
146.6
14.3
15
*
Z29
ICPC
Social problem NOS
7.4
14.1
33
44
N05AF03
ATC
chlorprothixene; systemic
26.6
14.1
19
7
N30.9
ICD-10 Finland
Cystitis, unspecified
2.8
13.6
87
307
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.7
13.4
343
2179
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.7
13.4
356
2287
I63.0
ICD-10 Finland
Cerebral infarction due to thrombosis of precerebral arteries
+∞
13.4
13
*
35399
ICD-8 Finland
Sciatica
+∞
13.4
13
*
G41.9
ICD-10 Finland
Status epilepticus, unspecified
+∞
13.4
13
*
AAA20
NOMESCO Finland
Insertion of intraventricular pressure monitoring device
+∞
13.4
13
*
C10AA01
ATC
simvastatin; oral
1.5
13.2
659
4934
N05AC02
ATC
thioridazine; oral
17.8
13.1
20
11
B01AC07
ATC
dipyridamole; systemic
2.5
13.1
102
405
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
5.1
12.9
40
77
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
7.1
12.9
31
43
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
22.0
12.7
18
8
SPAT1101
SPAT
Orthostatic test
2.9
12.7
79
277
N06AG02
ATC
moclobemide; oral
4.8
12.6
41
84
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
6.8
12.5
31
45
P29
ICPC
Psychological sympt/compl other
6.8
12.5
31
45
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
68.2
12.4
14
*
G91.0
ICD-10 Finland
Communicating hydrocephalus
+∞
12.4
12
*
F00.11
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset other additional symptoms, mainly paranoidism
+∞
12.4
12
*
N05AF05
ATC
zuclopenthixol; systemic
+∞
12.4
12
*
S72.1
ICD-10 Finland
Pertrochanteric fracture
3.2
12.3
65
204
B03BA03
ATC
hydroxocobalamin; parenteral
2.2
12.1
121
548
A69
ICPC
General and Unspecified, Other reason for encounter NEC
3.7
12.0
52
140
SPAT1139
SPAT
Nutrition survey
3.9
11.9
49
126
N05BA12
ATC
alprazolam; oral
2.4
11.9
102
429
U04
ICPC
Incontinence urine
2.9
11.9
73
252
F32.1
ICD-10 Finland
Moderate depressive episode
12.1
11.9
21
17
F34.1
ICD-10 Finland
Dysthymia
20.8
11.8
17
8
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.5
11.8
468
3308
H04AA01
ATC
glucagon; nasal, parenteral
8.0
11.8
26
32
N03AB02
ATC
phenytoin; systemic
13.1
11.7
20
15
SPAT1304
SPAT
Counselling and guidance related to ageing
2.1
11.6
129
609
P72
ICPC
Schizophrenia
63.4
11.4
13
*
30041
ICD-8 Finland
Neuroses, Depressiva
+∞
11.3
11
*
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
+∞
11.3
11
*
F31.0
ICD-10 Finland
Bipolar affective disorder, current episode hypomanic
+∞
11.3
11
*
S06.6
ICD-10 Finland
Traumatic subarachnoid haemorrhage
+∞
11.3
11
*
G25.8
ICD-10 Finland
Other specified extrapyramidal and movement disorders
+∞
11.3
11
*
F20.9
ICD-10 Finland
Schizophrenia, unspecified
+∞
11.3
11
*
F05.0
ICD-10 Finland
Delirium not superimposed on dementia, so described
117.0
11.3
12
*
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
2.1
11.2
124
589
I67.3
ICD-10 Finland
Progressive vascular leukoencephalopathy
11.5
11.1
20
17
G56.2
ICD-10 Finland
Lesion of ulnar nerve
11.5
11.1
20
17
I65.2
ICD-10 Finland
Occlusion and stenosis of carotid artery
34.2
11.1
14
*
N87
ICPC
Parkinsonism
34.2
11.1
14
*
C04AE01
ATC
ergoloid mesylates; systemic
6.2
11.1
29
46
N06AA09
ATC
amitriptyline; systemic
2.4
11.0
95
398
Z02.7
ICD-10 Finland
Issue of medical certificate
2.7
11.0
74
273
N39.9
ICD-10 Finland
Disorder of urinary system, unspecified
5.0
10.9
34
67
P01
ICPC
Feeling anxious/nervous/tense
4.3
10.9
39
89
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
2.1
10.8
121
574
N29
ICPC
Neurological sympt/complt other
7.8
10.8
24
30
G44.2
ICD-10 Finland
Tension-type headache
2.9
10.8
67
234
A10AE05
ATC
insulin detemir; parenteral
2.8
10.8
69
247
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.3
10.6
98
426
G45.3
ICD-10 Finland
Amaurosis fugax
27.3
10.6
14
5
I67.9
ICD-10 Finland
Cerebrovascular disease, unspecified
58.5
10.5
12
*
G04CA02
ATC
tamsulosin; oral
1.5
10.3
382
2645
2900A
ICD-9 Finland
Senile and presenile organic psychotic conditions, Senile dementia, uncomplicated
+∞
10.3
10
*
AA7AA
NOMESCO Finland
Liquor cerebri shunt X-ray examinatin without contrast
+∞
10.3
10
*
F00.02
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset other additional symptoms, mainly illusions
+∞
10.3
10
*
N07AA06
ATC
NA
+∞
10.3
10
*
G81.9
ICD-10 Finland
Hemiplegia, unspecified
+∞
10.3
10
*
N04BA03
ATC
levodopa, decarboxylase inhibitor and COMT inhibitor; oral
+∞
10.3
10
*
AAF00
NOMESCO Finland
Ventriculostomy
+∞
10.3
10
*
2968A
ICD-9 Finland
Affective psychoses, Manic-depressive psychosis, other and unspecified
+∞
10.3
10
*
SAD01
NOMESCO Finland
Assessment of need for oral health care, standard
2.2
10.3
104
474
I69.1
ICD-10 Finland
Sequelae of intracerebral haemorrhage
107.2
10.3
11
*
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.5
10.2
79
315
NFJ54
NOMESCO Finland
Internal fixation of fracture of upper femur with intramedullary nail
3.6
10.2
45
124
N06AA12
ATC
doxepin; systemic
2.8
10.2
63
220
N39.4
ICD-10 Finland
Other specified urinary incontinence
2.2
10.2
101
458
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
10.1
206
1217
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
2.7
10.1
67
244
N06AB05
ATC
paroxetine; oral
3.8
10.0
41
106
SPAT1231
SPAT
Assessment of adjustments needed in living environment
4.3
10.0
36
83
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
4.0
10.0
39
97
G04BD07
ATC
tolterodine; oral
2.3
10.0
87
371
S18
ICPC
Laceration/cut
0.6
9.9
248
3443
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
39.0
9.8
12
*
R41
ICD-10 Finland
Other symptoms and signs involving cognitive functions and awareness
9.8
9.8
19
19
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
16.3
9.7
15
9
K91
ICPC
Cerebrovascular disease
25.4
9.7
13
5
F01.29
ICD-10 Finland
Subcortical vascular dementia without information on additional symptoms
25.4
9.7
13
5
R99
ICD-10 Finland
Other ill-defined and unspecified causes of mortality
3.4
9.6
45
131
F06.9
ICD-10 Finland
Unspecified mental disorder due to brain damage and dysfunction and to physical disease
53.6
9.5
11
*
F99
ICD-10 Finland
Mental disorder, not otherwise specified
53.6
9.5
11
*
N06AX03
ATC
mianserin; oral
3.5
9.4
43
123
J01MA02
ATC
ciprofloxacin; systemic
1.4
9.3
516
3869
X59
ICD-10 Finland
Exposure to unspecified factor
1.8
9.3
172
985
G31.1
ICD-10 Finland
Senile degeneration of brain, not elsewhere classified
97.4
9.3
10
*
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
97.4
9.3
10
*
F02.09*G31.0
ICD-10 Finland
Dementia in Pick's disease without information on additional symptoms
+∞
9.3
9
*
F22.9
ICD-10 Finland
Persistent delusional disorder, unspecified
+∞
9.3
9
*
I63.5
ICD-10 Finland
Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
+∞
9.3
9
*
F009, F03
ICD-10 Finland
NA
+∞
9.3
9
*
ICC04
NOMESCO Finland
Psychiatric treatment plan, permanent discontinuation
+∞
9.3
9
*
G40.19
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
+∞
9.3
9
*
F0011, G301
ICD-10 Finland
NA
+∞
9.3
9
*
I63.1
ICD-10 Finland
Cerebral infarction due to embolism of precerebral arteries
+∞
9.3
9
*
G40.10
ICD-10 Finland
Simple partial seizures
+∞
9.3
9
*
G91.9
ICD-10 Finland
Hydrocephalus, unspecified
+∞
9.3
9
*
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
+∞
9.3
9
*
SPAT1240
SPAT
Therapeutic discussion
3.1
9.3
49
156
SPAT1167
SPAT
Insertion of urinary catheter
2.8
9.2
58
205
ZXD05
NOMESCO Finland
Urgent procedure
1.5
9.2
372
2614
N19
ICPC
Speech disorder
21.1
9.2
13
6
N99
ICPC
Neurological disease other
21.1
9.2
13
6
SPAT1307
SPAT
Psychosocial counselling and guidance
4.9
9.0
28
56
SPAT1153
SPAT
Removal of sutures
0.6
9.0
170
2512
A29
ICPC
General symptom/complaint other
1.9
8.9
134
718
EBA15
NOMESCO Finland
Extraction of large number of teeth
3.1
8.9
47
150
N06AX12
ATC
bupropion; oral
8.1
8.9
19
23
N18
ICPC
Paralysis/weakness
8.8
8.8
18
20
G04CB01
ATC
finasteride; oral (testosterone-5-alpha reductase inhibitors)
1.7
8.8
208
1281
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
5.4
8.8
25
45
SPAT1246
SPAT
Screening of depression or other psychiatric problem
5.3
8.6
25
46
SPAT1221
SPAT
Guidance concerning rehabilitation services and livelihood
8.4
8.6
18
21
D07AA02
ATC
hydrocortisone; topical
1.8
8.5
145
812
SPAT1262
SPAT
Handing over of treatment supplies
1.6
8.5
205
1273
E0000UV
ATC
NA
1.4
8.4
413
3015
SPAT1276
SPAT
Outlining of treatment with patient or their family members
3.6
8.4
36
98
P99
ICPC
Psychological disorders other
15.9
8.4
13
8
Z28
ICPC
Limited function/disability (Z)
11.3
8.4
15
13
F10.20
ICD-10 Finland
Alcohol dependence currently independent
87.7
8.3
9
*
N04BC04
ATC
ropinirole; oral
87.7
8.3
9
*
F10.09
ICD-10 Finland
Alcohol intoxication UNS
87.7
8.3
9
*
N05BE01
ATC
buspirone; oral
6.2
8.3
21
33
IGY01
NOMESCO Finland
Accelerated psychiatric treatment contact
+∞
8.2
8
*
ACC53
NOMESCO Finland
Release of ulnar nerve
+∞
8.2
8
*
G31.2
ICD-10 Finland
Degeneration of nervous system due to alcohol
+∞
8.2
8
*
F10.9
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Unspecified mental and behavioural disorder
+∞
8.2
8
*
I61.1
ICD-10 Finland
Intracerebral haemorrhage in hemisphere, cortical
+∞
8.2
8
*
3540A
ICD-9 Finland
Mononeuritis of upper limb and mononeuritis multiplex, Carpal tunnel syndrome
+∞
8.2
8
*
3310A
ICD-9 Finland
Other cerebral degenerations, Alzheimer's disease
+∞
8.2
8
*
F01.0
ICD-10 Finland
Vascular dementia of acute onset
+∞
8.2
8
*
R33
ICD-10 Finland
Retention of urine
1.8
8.2
135
747
8070/3-C34.9
ICD-O-3
Squamous cell carcinoma, NOS, of lung, NOS
0.1
8.1
*
256
R32
ICD-10 Finland
Unspecified urinary incontinence
3.2
8.1
40
122
A10BB12
ATC
glimepiride; oral
1.8
8.1
134
741
SPAT1263
SPAT
Sampling
1.4
8.1
444
3308
A03FA01
ATC
metoclopramide; systemic, rectal
0.6
8.1
127
1961
E87.0
ICD-10 Finland
Hyperosmolality and hypernatraemia
14.1
8.0
13
9
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
6.9
8.0
19
27
L82
ICD-10 Finland
Seborrhoeic keratosis
0.5
8.0
64
1187
A04AA01
ATC
ondansetron; systemic, rectal
0.3
8.0
14
482
K92.0
ICD-10 Finland
Haematemesis
2.9
8.0
47
162
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
2.8
7.8
48
170
P28
ICPC
Limited function/disability (P)
12.7
7.7
13
10
R23.8
ICD-10 Finland
Other and unspecified skin changes
0.5
7.7
60
1122
SPAT1050
SPAT
Extensive neurological examination
4.6
7.7
25
53
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.6
7.7
198
1247
SPAT1243
SPAT
Psychiatric/psychological examination
10.5
7.6
14
13
SPAT1305
SPAT
Counselling and guidance related to physical exercise
1.9
7.6
104
538
N05AL01
ATC
sulpiride; systemic
8.2
7.6
16
19
D07BA04
ATC
hydrocortisone and antiseptics; topical
1.9
7.6
104
539
M03BX01
ATC
baclofen; systemic
9.2
7.6
15
16
IGY02
NOMESCO Finland
Psychiatric monitoring contact
43.8
7.6
9
*
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
2.2
7.6
71
315
A10AB04
ATC
insulin lispro; parenteral (insulins and analog. for injection, fast-acting)
3.8
7.6
30
77
A02BC03
ATC
lansoprazole; oral
1.4
7.6
357
2577
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.5
7.6
334
2382
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
7.5
338
2421
P76
ICPC
Depressive disorder
5.1
7.5
22
42
Z03.2
ICD-10 Finland
Observation for suspected mental and behavioural disorders
24.3
7.5
10
*
ZXE10
NOMESCO Finland
More than one and less than three hours
1.4
7.4
429
3216
P03
ICPC
Feeling depressed
3.4
7.4
34
99
I63.8
ICD-10 Finland
Other cerebral infarction
77.9
7.3
8
*
Z60.8
ICD-10 Finland
Other problems related to social environment
77.9
7.3
8
*
PAF14
NOMESCO Finland
Thrombendarterectomy of internal carotid artery
77.9
7.3
8
*
F10.25
ICD-10 Finland
Alcohol dependence continuous use
77.9
7.3
8
*
R40.0
ICD-10 Finland
Somnolence
77.9
7.3
8
*
R40.2
ICD-10 Finland
Coma, unspecified
6.9
7.3
17
24
G51.0
ICD-10 Finland
Bell palsy
13.0
7.2
12
9
H02AA02
ATC
fludrocortisone; oral
7.4
7.2
16
21
3039X
ICD-9 Finland
Alcohol dependence syndrome, Other and unspecified alcohol dependence
+∞
7.2
7
*
AAC00
NOMESCO Finland
Ligature of intracranial aneurysm
+∞
7.2
7
*
G21.9
ICD-10 Finland
Secondary parkinsonism, unspecified
+∞
7.2
7
*
29599
ICD-8 Finland
Schizophrenia, Unspecified type
+∞
7.2
7
*
G97.0
ICD-10 Finland
Cerebrospinal fluid leak from spinal puncture
+∞
7.2
7
*
30320
ICD-8 Finland
Alcoholism, Alcoholic addiction
+∞
7.2
7
*
G40.21
ICD-10 Finland
Partial epileptic seizure with cloudiness and automatism
+∞
7.2
7
*
F20.09
ICD-10 Finland
Paranoid schizophrenia UNS
+∞
7.2
7
*
F00, F03
ICD-10 Finland
NA
+∞
7.2
7
*
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
+∞
7.2
7
*
F0002, G300
ICD-10 Finland
NA
+∞
7.2
7
*
KMAK
NOMESCO Finland
NA
1.4
7.2
422
3168
WX402
NOMESCO Finland
General anaesthesia
0.4
7.2
40
836
SPAT1279
SPAT
Preparation of immediate hospitalisation
4.0
7.1
27
67
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
15.3
7.1
11
7
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.3
7.1
64
279
Z75.0
ICD-10 Finland
Medical services not available in home
29.2
7.0
9
*
T90.5
ICD-10 Finland
Sequelae of intracranial injury
29.2
7.0
9
*
I95.9
ICD-10 Finland
Hypotension, unspecified
4.4
7.0
24
54
Z60.9
ICD-10 Finland
Problem related to social environment, unspecified
19.5
7.0
10
5
N05AC01
ATC
periciazine; systemic
19.5
7.0
10
5
SPAT1104
SPAT
Monitoring of emergency patient
2.1
7.0
78
372
S22.3
ICD-10 Finland
Fracture of rib
2.2
7.0
71
325
N03AX16
ATC
pregabalin; oral
1.6
6.9
189
1212
N06AX05
ATC
trazodone; oral
5.9
6.9
18
30
T89
ICPC
Diabetes insulin dependent
3.7
6.8
28
75
JN4AD
NOMESCO Finland
Body CT examination
0.4
6.8
20
538
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
4.8
6.8
21
43
E11.4
ICD-10 Finland
Type 2 diabetes mellitus, with neurological complications
4.0
6.8
25
61
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.6
6.7
163
1012
SCA01
NOMESCO Finland
Simple analysis and advice of nutrition with regard to dentistry
1.6
6.7
197
1281
G04BD08
ATC
solifenacin; oral
2.0
6.7
87
444
F10.24
ICD-10 Finland
Alcohol depence active use
38.9
6.7
8
*
K86
ICPC
Hypertension uncomplicated
0.5
6.6
52
971
XF606
NOMESCO Finland
Ortostatic test
9.1
6.6
13
14
F41.1
ICD-10 Finland
Generalized anxiety disorder
9.1
6.6
13
14
N06AX18
ATC
reboxetine; oral
16.2
6.6
10
6
A06AC01
ATC
ispaghula (psylla seeds); oral
1.4
6.6
283
2003
ZXD35
NOMESCO Finland
Usual procedure
2.6
6.5
43
161
R26.8
ICD-10 Finland
Other and unspecified abnormalities of gait and mobility
4.8
6.5
20
41
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
2.3
6.5
55
234
D07CA01
ATC
hydrocortisone and antibiotics; topical
1.6
6.5
149
911
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
11.9
6.5
11
9
L57.0
ICD-10 Finland
Actinic keratosis
0.5
6.4
61
1075
PA7BD
NOMESCO Finland
CT angiography of neck and brain
9.7
6.4
12
12
SPAT1138
SPAT
Guidance concerning bowel function
3.9
6.4
24
60
S00.0
ICD-10 Finland
Superficial injury of scalp
3.8
6.3
25
65
P04
ICPC
Feeling/behaving irritable/angry
67.9
6.3
7
*
Z10.1
ICD-10 Finland
Routine general health check-up of inhabitants of institutions
67.9
6.3
7
*
SPAT1215
SPAT
Assessment of need for medical rehabilitation
2.8
6.3
37
128
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
0.6
6.3
109
1650
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.4
6.3
282
2010
SPAT1100
SPAT
Long-term monitoring of blood pressure
1.8
6.3
99
540
H81.9
ICD-10 Finland
Disorder of vestibular function, unspecified
6.0
6.3
16
26
NE1AA
NOMESCO Finland
Pelvis X-ray examination
1.9
6.3
88
463
213
Kela drug reimbursment
Fat metabolism disorder associated with chronic coronary artery disease
1.6
6.3
152
941
103
Kela drug reimbursment
Diabetes, insulin-treated
1.4
6.3
351
2608
-2
ICPC
NA
5.2
6.3
18
34
N02AJ06
ATC
codeine and paracetamol; systemic
0.7
6.2
155
2175
4912B
ICD-9 Finland
Chronic bronchitis, Obstructive chronic bronchitis[BRONCHITIS OBSTRUCTIVA CUM EMPHYSEMATE]
0.1
6.2
*
230
V700A
ICD-9 Finland
General medical examination, Routine general medical examination at a health care facility
3.0
6.2
32
103
C34.1
ICD-10 Finland
Malignant neoplasm: Upper lobe, bronchus or lung
0.2
6.2
7
307
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
7.9
6.2
13
16
F25.9
ICD-10 Finland
Schizoaffective disorder, unspecified
+∞
6.2
6
*
F00.03
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenil onset other additional symptoms, mainly depression
+∞
6.2
6
*
G21.1
ICD-10 Finland
Other drug-induced secondary parkinsonism
+∞
6.2
6
*
S06.9
ICD-10 Finland
Intracranial injury, unspecified
+∞
6.2
6
*
F20.30
ICD-10 Finland
Undifferentiated schizophrenia continuous
+∞
6.2
6
*
AAF20
NOMESCO Finland
Revision of shunt of ventricle of brain
+∞
6.2
6
*
G40.09
ICD-10 Finland
Other or unspecified partial (focal) idiopathic epilepsy or epileptic syndrome with local onset
+∞
6.2
6
*
4359X
ICD-9 Finland
Transient cerebral ischaemia, Unspecified transient cerebral ischaemia
+∞
6.2
6
*
F31.30
ICD-10 Finland
Bipolar disorder Depressive episode without somatic syndrome
+∞
6.2
6
*
G40
ICD-10 Finland
Epilepsy
+∞
6.2
6
*
F00.21
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type of other additional symptoms, mainly paranoidism
+∞
6.2
6
*
F0009, G301
ICD-10 Finland
NA
+∞
6.2
6
*
F01.19
ICD-10 Finland
Multi-infarct dementia without information on additional symptoms
+∞
6.2
6
*
G44.0
ICD-10 Finland
Cluster headache syndrome
+∞
6.2
6
*
30040
ICD-8 Finland
Neuroses, Neurotico-depressiva
+∞
6.2
6
*
F31.8
ICD-10 Finland
Other bipolar affective disorders
+∞
6.2
6
*
3074A
ICD-9 Finland
Special symptoms or syndromes not elsewhere classified, Specific disorders of sleep of nonorganic origin[UNIHÄIRIÖ]
+∞
6.2
6
*
F31.4
ICD-10 Finland
Bipolar affective disorder, current episode severe depression without psychotic symptoms
+∞
6.2
6
*
F31.7
ICD-10 Finland
Bipolar affective disorder, currently in remission
+∞
6.2
6
*
WX780
NOMESCO Finland
Remote monitoring CPAP
+∞
6.2
6
*
F33.30
ICD-10 Finland
Recurrent depression, severe episode without somatic syndrome
+∞
6.2
6
*
F31.1
ICD-10 Finland
Bipolar affective disorder, current episode manic without psychotic symptoms
+∞
6.2
6
*
F06.0
ICD-10 Finland
Organic hallucinosis
+∞
6.2
6
*
F0001, G301
ICD-10 Finland
NA
+∞
6.2
6
*
F10.73
ICD-10 Finland
Residual or late-onset psychosis caused by alcohol dementia
+∞
6.2
6
*
F0003, G300
ICD-10 Finland
NA
+∞
6.2
6
*
30300
ICD-8 Finland
Alcoholism, Episodic excessive drinking
+∞
6.2
6
*
N03AX18
ATC
lacosamide; systemic
+∞
6.2
6
*
F00.13
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset other additional symptoms, mainly depression
+∞
6.2
6
*
F0023, G308
ICD-10 Finland
NA
+∞
6.2
6
*
F01.20
ICD-10 Finland
Subcortical vascular dementia without additional symptoms
10.7
6.2
11
10
A10BA02
ATC
metformin; oral
1.4
6.2
348
2587
XA400
NOMESCO Finland
EEG
17.5
6.2
9
5
W00
ICD-10 Finland
Fall on same level involving ice and snow
1.8
6.1
105
591
L01BC06
ATC
capecitabine; oral
0.2
6.1
6
287
C03CA01
ATC
furosemide; systemic
1.3
6.1
554
4442
M01AB55
ATC
diclofenac, combinations; oral
1.8
6.1
92
497
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
1.7
6.1
115
667
WF049
NOMESCO Finland
Radiotherapy of metastasis
0.2
6.1
*
244
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.8
6.1
108
615
N05AF01
ATC
flupentixol; systemic
6.8
6.1
14
20
M01AE03
ATC
ketoprofen; systemic, rectal
1.3
6.0
462
3612
Mortality – FinRegistry
↥Association
Association between endpoint AD_EO_EXMORE and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| AD_EO_EXMORE | 2.808 [2.51, 3.15] | < 0.001 |
| Birth year | 0.991 [0.98, 1.0] | 0.029 |
During the follow-up period (1.1.1998 — 31.12.2019), 13192 out of 17872 females with AD_EO_EXMORE died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| AD_EO_EXMORE | 3.402 [2.88, 4.02] | < 0.001 |
| Birth year | 0.985 [0.98, 0.99] | 0.002 |
During the follow-up period (1.1.1998 — 31.12.2019), 7808 out of 10340 males with AD_EO_EXMORE died.
Mortality risk
Mortality risk for people of age
years, who have AD_EO_EXMORE.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.233% | 0.648% |
| 5 | 1.348% | 3.521% |
| 10 | 3.498% | 8.812% |
| 15 | 6.322% | 15.839% |
| 20 | 10.973% | 25.691% |
Relationships between endpoints
↥Index endpoint: AD_EO_EXMORE – Alzheimer’s disease (Early onset), excluding more controls
GWS hits: 4
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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