Alzheimer’s disease (Early onset), excluding more controls

AD_EO_EXMORE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

-

2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

None

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude
G6_AD_STRICT, F5_DEMENTIA, F5_DEMENTIA_U, F5_PSYCH, NEURODIS, MEMLOSS, TRAUMBRAIN_NONCONCUS

Extra metadata

First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 1965 967 998
Unadjusted period prevalence (%) 0.40 0.34 0.46
Median age at first event (years) 75.62 73.65 77.54

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2006
Matched controls
18893
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
TAB00
NOMESCO Finland
Lumbar puncture
54.4
307.7
253
50
F03
ICD-10 Finland
Unspecified dementia
112.5
307.7
454
49
N03AG01
ATC
valproic acid; systemic, rectal
154.3
307.7
206
14
N06DA02
ATC
donepezil; oral
1004.4
307.7
1082
22
P20
ICPC
Memory disturbance
13.2
307.7
739
800
307
Kela drug reimbursment
Tacrine, donepezil, rivastigmine, galantamine and other major and expensive drugs used to treat Alzheimer's disease
+∞
307.7
1109
*
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
248.2
307.7
233
10
F00.10*G30.1
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset without additional symptoms
560.6
307.7
527
12
P70
ICPC
Dementia
77.8
307.7
272
38
XA800
NOMESCO Finland
Neuropsychological investigation
79.9
307.7
199
26
G30.9
ICD-10 Finland
Alzheimer disease, unspecified
5878.0
307.7
801
*
G30.0
ICD-10 Finland
Alzheimer disease with early onset
16384.0
307.7
1145
*
N06DX01
ATC
memantine; oral
1065.7
307.7
1229
28
N05AX08
ATC
risperidone; systemic
80.6
307.7
682
120
G30.1
ICD-10 Finland
Alzheimer disease with late onset
660.2
307.7
936
25
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
25.6
307.7
624
328
F00.00*G30.0
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset without additional symptoms
+∞
307.7
713
*
N05AH04
ATC
quetiapine; oral
27.9
307.7
583
273
N06DA03
ATC
rivastigmine; oral, transdermal
1064.7
307.7
678
9
N06DA04
ATC
galantamine; oral
1092.0
304.9
297
*
F00.20*G30.8
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type without additional symptoms
98.2
297.4
163
17
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
97.5
295.4
162
17
F06.7
ICD-10 Finland
Mild cognitive disorder
34.2
284.0
191
58
F0009, G300,
ICD-10 Finland
+∞
282.3
270
*
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
58.0
268.4
159
28
S06.0
ICD-10 Finland
Concussion
25.3
247.8
184
75
F32.9
ICD-10 Finland
Depressive episode, unspecified
26.3
244.7
179
70
G30
ICD-10 Finland
Alzheimer disease
829.2
237.5
234
*
N05AH03
ATC
olanzapine; systemic
50.9
232.2
141
28
G30.8
ICD-10 Finland
Other Alzheimer disease
316.2
231.7
236
8
F00.10
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset without additional symptoms
1173.5
226.6
222
*
SPAT1053
SPAT
Memory test
5.4
221.6
547
1219
N05BA04
ATC
oxazepam; oral
4.8
218.5
665
1764
N06AX11
ATC
mirtazapine; oral
4.6
208.7
683
1910
R41.3
ICD-10 Finland
Other amnesia
30.4
207.4
144
48
F00.00
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset without additional symptoms
+∞
205.5
198
*
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
12.3
199.1
213
181
N06AB04
ATC
citalopram; systemic
5.2
194.3
485
1082
N06AB10
ATC
escitalopram; oral
6.6
191.7
351
585
F0019, G301,
ICD-10 Finland
+∞
187.5
181
*
AA1AD
NOMESCO Finland
CT of head and brain
4.8
186.2
533
1329
SPAT1245
SPAT
Provision of support and information to patient’s family members
8.8
171.2
235
282
R53
ICD-10 Finland
Malaise and fatigue
4.1
161.6
589
1747
Z75.5
ICD-10 Finland
Holiday relief care
28.3
156.7
111
39
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
12.5
149.2
156
127
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
11.3
144.2
161
145
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
+∞
142.4
138
*
Z2445
NOMESCO Finland
Psychologist
66.2
140.0
81
12
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
7.1
136.1
223
327
R56.8
ICD-10 Finland
Other and unspecified convulsions
15.2
136.0
126
83
N04BA02
ATC
levodopa and decarboxylase inhibitor; oral
24.4
135.4
101
41
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
+∞
135.0
131
*
F009, G309,
ICD-10 Finland
+∞
130.9
127
*
WYA20
NOMESCO Finland
Home visit
22.0
126.3
98
44
R41.0
ICD-10 Finland
Disorientation, unspecified
12.2
123.2
130
107
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
3.1
122.1
756
3071
A28
ICPC
Limited function/disability NOS
3.5
119.3
543
1830
SPAT1234
SPAT
Support of social functional capacity
6.5
119.1
211
335
N05AD01
ATC
haloperidol; systemic
8.5
117.9
162
193
G47.3
ICD-10 Finland
Sleep apnoea
9.6
112.8
140
146
SPAT1216
SPAT
Assessment of functional ability
3.7
112.8
439
1332
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
7.4
112.6
175
241
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
5.0
110.3
267
566
F00.9
ICD-10 Finland
Dementia in Alzheimer disease, unspecified
+∞
102.8
100
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.3
102.5
487
1670
N05BA06
ATC
lorazepam; systemic, sublingual
6.3
101.4
183
295
F51.0
ICD-10 Finland
Nonorganic insomnia
+∞
97.6
95
*
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.4
96.1
416
1342
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
4.2
95.3
286
717
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.7
94.6
785
3635
N05AD03
ATC
melperone; systemic
20.3
93.8
75
36
N06AX26
ATC
vortioxetine; oral
12.1
92.3
97
79
G40.9
ICD-10 Finland
Epilepsy, unspecified
456.8
91.9
93
*
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
31.2
89.0
61
19
G56.0
ICD-10 Finland
Carpal tunnel syndrome
9.2
88.5
113
122
A06AD11
ATC
lactulose; oral
3.0
88.2
493
1843
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
40.9
86.4
55
13
N06AB06
ATC
sertraline; oral
6.3
85.1
152
242
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
21.4
84.4
66
30
SPAT1254
SPAT
Administration of medicine
3.3
83.6
386
1287
S06.5
ICD-10 Finland
Traumatic subdural haemorrhage
+∞
79.0
77
*
F05.1
ICD-10 Finland
Delirium superimposed on dementia
+∞
74.8
73
*
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
3.1
74.3
380
1339
F01.9
ICD-10 Finland
Vascular dementia, unspecified
35.6
72.7
48
13
SPAT1222
SPAT
Counselling/guidance promoting independent living
3.0
72.7
381
1361
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
9.8
69.5
84
84
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.9
66.7
386
1451
N06AX16
ATC
venlafaxine; oral
5.2
65.9
143
273
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
+∞
65.5
64
*
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
630.8
64.8
65
*
G91.2
ICD-10 Finland
Normal-pressure hydrocephalus
+∞
64.5
63
*
F05.9
ICD-10 Finland
Delirium, unspecified
99.0
63.6
71
7
N03AX14
ATC
levetiracetam; systemic
24.6
62.1
46
18
L28
ICPC
Limited function/disability (L)
2.7
61.2
402
1608
G20
ICD-10 Finland
Parkinson disease
107.1
59.7
66
6
SPAT1229
SPAT
Assessment of need for aid
3.8
57.9
191
507
T36
ICD-10 Finland
Poisoning by systemic antibiotics
15.2
56.8
52
33
R55
ICD-10 Finland
Syncope and collapse
3.0
54.5
271
931
N03AF02
ATC
oxcarbazepine; oral
21.2
53.6
42
19
F00.20
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type without additional symptoms
267.3
53.2
55
*
110
Kela drug reimbursment
Parkinson's disease and comparable movement disrorders
+∞
52.2
51
*
F00.09
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset information on additional symptoms is lacking
+∞
52.2
51
*
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
7.8
50.8
73
91
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
170.8
49.9
53
*
R42
ICD-10 Finland
Dizziness and giddiness
2.4
49.4
424
1908
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
+∞
47.0
46
*
N05AB03
ATC
perphenazine; systemic, rectal
14.8
46.3
43
28
W19
ICD-10 Finland
Unspecified fall
3.3
46.1
192
592
S72.0
ICD-10 Finland
Fracture of neck of femur
3.5
44.6
163
462
N05CD07
ATC
temazepam; oral
2.5
43.5
324
1361
N03AE01
ATC
clonazepam; systemic
6.1
43.1
78
125
N02AA05
ATC
oxycodone; systemic
2.2
42.5
433
2083
SPAT1251
SPAT
Organisation of medication
4.2
42.3
118
276
K90
ICPC
Stroke/cerebrovascular accident
17.6
41.2
35
19
E86
ICD-10 Finland
Volume depletion
5.3
40.9
86
159
G45.0
ICD-10 Finland
Vertebro-basilar artery syndrome
391.8
40.3
41
*
SAB01
NOMESCO Finland
Restricted oral and dental health check by dental hygienist or dental assistant
3.6
40.0
141
390
N06AX21
ATC
duloxetine; oral
3.9
39.4
121
304
N03AF01
ATC
carbamazepine; oral, rectal
5.0
39.1
88
173
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
+∞
38.8
38
*
J01CA08
ATC
pivmecillinam; oral
1.9
38.8
719
4278
A10AB05
ATC
insulin aspart; parenteral
3.3
38.8
154
460
N05CF01
ATC
zopiclone; oral
2.0
38.7
632
3604
ACC51
NOMESCO Finland
Release of median nerve
61.8
38.2
45
7
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
13.0
38.2
38
28
G45.1
ICD-10 Finland
Carotid artery syndrome (hemispheric)
131.3
37.9
41
*
F00.01
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset other additional symptoms, mainly paranoidism
+∞
36.8
36
*
A04
ICPC
Weakness/tiredness general
2.5
36.4
259
1061
N02BE01
ATC
paracetamol; systemic, rectal
2.0
36.0
1538
11780
I63.4
ICD-10 Finland
Cerebral infarction due to embolism of cerebral arteries
+∞
35.7
35
*
AAD10
NOMESCO Finland
Evacuation of chronic subdural haematoma
+∞
35.7
35
*
F00
ICD-10 Finland
Dementia in Alzheimer disease
342.7
35.2
36
*
SPAT1246
SPAT
Screening of depression or other psychiatric problem
9.8
35.2
42
41
S70.0
ICD-10 Finland
Contusion of hip
4.0
35.1
103
250
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
+∞
34.7
34
*
R1250
NOMESCO Finland
Evaluation of functional capability
8.5
34.6
46
52
N28
ICPC
Limited function/disability (N)
14.6
34.2
32
21
N06AB03
ATC
fluoxetine; oral
3.2
34.1
147
461
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
2.5
34.0
236
954
F22.0
ICD-10 Finland
Delusional disorder
118.3
33.9
37
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.3
33.7
287
1271
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
4.2
33.4
91
209
F29
ICD-10 Finland
Unspecified nonorganic psychosis
88.8
33.0
37
*
SPAT1301
SPAT
No procedures
1.9
32.8
537
3037
F0029, G308,
ICD-10 Finland
+∞
32.7
32
*
N30.0
ICD-10 Finland
Acute cystitis
2.3
32.6
287
1288
N05BA01
ATC
diazepam; systemic, rectal
2.5
32.4
228
927
N30.9
ICD-10 Finland
Cystitis, unspecified
3.2
32.4
139
435
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.2
32.3
303
1396
G72.8
ICD-10 Finland
Other specified myopathies
313.2
32.2
33
*
NFB20
NOMESCO Finland
Primary partial prosthetic replacement of hip joint using cement, other or unspecified
3.8
32.0
102
263
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.3
32.0
260
1128
N05AA02
ATC
levomepromazine; systemic
5.6
31.8
62
107
SPAT1252
SPAT
Overall medication plan or its review
2.9
31.1
155
528
P29
ICPC
Psychological sympt/compl other
7.0
30.7
48
66
J01EA01
ATC
trimethoprim; systemic
1.9
30.4
537
3100
G31.0
ICD-10 Finland
Circumscribed brain atrophy
299.0
30.2
31
*
N07AA05, ,
ATC
+∞
29.6
29
*
F0014, G301,
ICD-10 Finland
+∞
29.6
29
*
Z29
ICPC
Social problem NOS
6.8
29.5
47
66
85000
ICD-8 Finland
Concussion, Current or unspecified
+∞
28.6
28
*
Z02.4
ICD-10 Finland
Examination for driving licence
0.4
28.4
145
3191
F32.1
ICD-10 Finland
Moderate depressive episode
11.0
28.0
31
27
G40.2
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
+∞
27.5
27
*
F00.1
ICD-10 Finland
Dementia in Alzheimer disease with late onset
+∞
27.5
27
*
N03AX09
ATC
lamotrigine; oral
29.6
27.3
37
12
S01.0
ICD-10 Finland
Open wound of scalp
2.9
27.3
136
463
I95.1
ICD-10 Finland
Orthostatic hypotension
3.7
26.9
88
231
G44.2
ICD-10 Finland
Tension-type headache
3.3
26.6
106
317
N29
ICPC
Neurological sympt/complt other
10.6
26.6
30
27
A10AE04
ATC
insulin glargine; parenteral
2.5
26.0
172
677
L89
ICD-10 Finland
Decubitus ulcer and pressure area
5.3
26.0
54
99
130
Kela drug reimbursment
Malignant tumour
0.2
25.9
29
1521
Z02.7
ICD-10 Finland
Issue of medical certificate
3.0
25.5
116
375
F0004, G300,
ICD-10 Finland
+∞
25.5
25
*
F00.14
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset other additional symptoms of mixed type
+∞
25.5
25
*
F00.04
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset other additional symptoms of mixed type
+∞
25.5
25
*
SPAT1172
SPAT
Guidance concerning hydration
3.8
25.4
79
200
N05AN01
ATC
lithium; oral
69.4
25.2
29
*
SPAT1101
SPAT
Orthostatic test
3.1
24.9
109
345
J01DB01
ATC
cefalexin; oral
1.7
24.9
1297
9897
H04AA01
ATC
glucagon; nasal, parenteral
8.1
24.8
34
40
U04
ICPC
Incontinence urine
3.0
24.5
110
353
R51.80
ICD-10 Finland
Headache
2.7
24.5
137
496
I61.9
ICD-10 Finland
Intracerebral haemorrhage, unspecified
+∞
24.5
24
*
F001, G301,
ICD-10 Finland
+∞
24.5
24
*
-, ,
ICD-10 Finland
4.2
24.2
65
148
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
124.0
24.0
26
*
E000001, ,
ATC
1.9
23.8
325
1710
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
5.4
23.5
47
83
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
2.0
23.5
303
1564
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
+∞
23.5
23
*
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
53.4
23.4
28
5
F00.19
ICD-10 Finland
Dementia in Alzheimer's disease with late onset without information about additional symptoms
228.7
23.1
24
*
F00.0
ICD-10 Finland
Dementia in Alzheimer disease with early onset
228.7
23.1
24
*
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
228.7
23.1
24
*
G31.8
ICD-10 Finland
Other specified degenerative diseases of nervous system
119.2
23.0
25
*
SPAT1360
SPAT
Extensive global examination
2.7
22.6
130
477
N06AX12
ATC
bupropion; oral
6.8
22.4
36
51
S72.1
ICD-10 Finland
Pertrochanteric fracture
3.3
22.1
87
258
LAITO, ,
NOMESCO Finland
114.3
22.1
24
*
N39.9
ICD-10 Finland
Disorder of urinary system, unspecified
5.1
21.7
46
86
SPAT1304
SPAT
Counselling and guidance related to ageing
2.3
21.6
182
798
S06.2
ICD-10 Finland
Diffuse brain injury
+∞
21.4
21
*
F02.39*G20
ICD-10 Finland
Dementia in Parkinson's disease without information on additional symptoms
+∞
21.4
21
*
N05AH02
ATC
clozapine; systemic
+∞
21.4
21
*
SPAT1139
SPAT
Nutrition survey
3.8
21.4
67
171
R11
ICD-10 Finland
Nausea and vomiting
2.4
21.3
152
620
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.7
21.2
463
2805
S06.3
ICD-10 Finland
Focal brain injury
209.4
21.1
22
*
I64
ICD-10 Finland
Stroke, not specified as haemorrhage or infarction
209.4
21.1
22
*
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.5
20.7
131
504
I62.0
ICD-10 Finland
Nontraumatic subdural haemorrhage
+∞
20.4
20
*
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
+∞
20.4
20
*
G31.9
ICD-10 Finland
Degenerative disease of nervous system, unspecified
+∞
20.4
20
*
SPAT1050
SPAT
Extensive neurological examination
5.8
20.3
38
63
AA5DR
NOMESCO Finland
Brain metabolism PET with CT
199.8
20.1
21
*
N05AX12
ATC
aripiprazole; systemic
199.8
20.1
21
*
I67.1
ICD-10 Finland
Cerebral aneurysm, nonruptured
199.8
20.1
21
*
N87
ICPC
Parkinsonism
104.7
20.1
22
*
F34.1
ICD-10 Finland
Dysthymia
31.0
19.6
26
8
R99
ICD-10 Finland
Other ill-defined and unspecified causes of mortality
3.4
19.6
71
200
N05BE01
ATC
buspirone; oral
8.0
19.5
27
32
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.0
19.3
248
1273
N04AA02
ATC
biperiden; systemic
34.0
19.3
25
7
N06AX03
ATC
mianserin; oral
3.8
18.9
59
150
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.6
18.9
632
4247
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
5.6
18.8
36
61
B03BA03
ATC
hydroxocobalamin; parenteral
2.3
18.8
150
642
N06AA09
ATC
amitriptyline; systemic
2.5
18.7
123
482
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
2.2
18.7
168
755
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
43.8
18.7
23
5
SPAT1231
SPAT
Assessment of adjustments needed in living environment
4.6
18.7
45
94
SPAT1240
SPAT
Therapeutic discussion
3.5
18.6
64
174
N06AG02
ATC
moclobemide; oral
4.2
18.6
50
114
P76
ICPC
Depressive disorder
5.7
18.4
35
59
I60.9
ICD-10 Finland
Subarachnoid haemorrhage, unspecified
+∞
18.4
18
*
F00.02
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset other additional symptoms, mainly illusions
+∞
18.4
18
*
F000, G300,
ICD-10 Finland
+∞
18.4
18
*
SPAT1307
SPAT
Psychosocial counselling and guidance
5.4
18.3
37
66
NFJ54
NOMESCO Finland
Internal fixation of fracture of upper femur with intramedullary nail
3.6
18.1
60
159
G45.3
ICD-10 Finland
Amaurosis fugax
180.6
18.1
19
*
SPAT1279
SPAT
Preparation of immediate hospitalisation
4.7
18.1
42
85
A29
ICPC
General symptom/complaint other
2.0
17.9
207
1024
B01AC07
ATC
dipyridamole; systemic
2.4
17.8
123
494
J01MA02
ATC
ciprofloxacin; systemic
1.5
17.7
686
4752
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
5.9
17.5
32
52
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
5.2
17.3
36
66
I61.0
ICD-10 Finland
Intracerebral haemorrhage in hemisphere, subcortical
+∞
17.3
17
*
3472A
ICD-9 Finland
Cataplexy and narcolepsy[OBSTRUKTIIVINEN UNIAPNEA]
+∞
17.3
17
*
G25.8
ICD-10 Finland
Other specified extrapyramidal and movement disorders
+∞
17.3
17
*
35399
ICD-8 Finland
Sciatica
+∞
17.3
17
*
N04BD01
ATC
selegiline; oral
63.3
17.3
20
*
F32
ICD-10 Finland
Depressive episode
5.6
17.2
33
56
C04AE01
ATC
ergoloid mesylates; systemic
5.5
16.9
33
57
P01
ICPC
Feeling anxious/nervous/tense
3.7
16.9
54
140
N03AB02
ATC
phenytoin; systemic
14.8
16.9
28
18
F05.8
ICD-10 Finland
Other delirium
47.5
16.5
20
*
SPAT1263
SPAT
Sampling
1.6
16.5
591
4010
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.6
16.4
95
350
C10AA01
ATC
simvastatin; oral
1.5
16.3
825
6017
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
3.8
16.3
51
130
G41.9
ICD-10 Finland
Status epilepticus, unspecified
+∞
16.3
16
*
SPAT1104
SPAT
Monitoring of emergency patient
2.5
16.2
108
427
SPAT1305
SPAT
Counselling and guidance related to physical exercise
2.2
16.1
143
640
H02AB02
ATC
dexamethasone; systemic
0.3
15.8
45
1338
SPAT1167
SPAT
Insertion of urinary catheter
2.9
15.7
75
250
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
28.5
15.6
21
7
SAD01
NOMESCO Finland
Assessment of need for oral health care, standard
2.1
15.6
159
750
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
4.5
15.6
38
80
N05AF03
ATC
chlorprothixene; systemic
19.9
15.5
23
11
N06AB05
ATC
paroxetine; oral
3.5
15.4
54
149
G04BD07
ATC
tolterodine; oral
2.4
15.4
107
431
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
+∞
15.3
15
*
G81.9
ICD-10 Finland
Hemiplegia, unspecified
+∞
15.3
15
*
F00.11
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset other additional symptoms, mainly paranoidism
+∞
15.3
15
*
G91.0
ICD-10 Finland
Communicating hydrocephalus
+∞
15.3
15
*
F0001, G300,
ICD-10 Finland
+∞
15.3
15
*
I69.0
ICD-10 Finland
Sequelae of subarachnoid haemorrhage
+∞
15.3
15
*
F0009, G309,
ICD-10 Finland
+∞
15.3
15
*
I69.1
ICD-10 Finland
Sequelae of intracerebral haemorrhage
+∞
15.3
15
*
I63.0
ICD-10 Finland
Cerebral infarction due to thrombosis of precerebral arteries
+∞
15.3
15
*
Z13.3
ICD-10 Finland
Special screening examination for mental and behavioural disorders
80.8
15.2
17
*
X59
ICD-10 Finland
Exposure to unspecified factor
1.8
15.1
233
1268
N05BA12
ATC
alprazolam; oral
2.2
14.9
124
540
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
2.7
14.8
83
301
N06AA12
ATC
doxepin; systemic
2.8
14.6
75
260
P03
ICPC
Feeling depressed
3.7
14.5
46
119
I67.9
ICD-10 Finland
Cerebrovascular disease, unspecified
53.8
14.4
17
*
F31.0
ICD-10 Finland
Bipolar affective disorder, current episode hypomanic
+∞
14.3
14
*
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
+∞
14.3
14
*
F20.9
ICD-10 Finland
Schizophrenia, unspecified
+∞
14.3
14
*
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
+∞
14.3
14
*
F05.0
ICD-10 Finland
Delirium not superimposed on dementia, so described
76.0
14.2
16
*
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
17.4
14.2
22
12
IGY02
NOMESCO Finland
Psychiatric monitoring contact
142.3
14.1
15
*
G31.1
ICD-10 Finland
Senile degeneration of brain, not elsewhere classified
142.3
14.1
15
*
I65.2
ICD-10 Finland
Occlusion and stenosis of carotid artery
34.2
14.0
18
5
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.8
14.0
225
1238
R26.8
ICD-10 Finland
Other and unspecified abnormalities of gait and mobility
5.8
14.0
26
43
A69
ICPC
General and Unspecified, Other reason for encounter NEC
3.1
13.5
57
177
P28
ICPC
Limited function/disability (P)
28.5
13.5
18
6
P72
ICPC
Schizophrenia
50.6
13.4
16
*
I67.3
ICD-10 Finland
Progressive vascular leukoencephalopathy
14.9
13.4
22
14
EBA15
NOMESCO Finland
Extraction of multiple teeth
2.9
13.4
65
219
E87.0
ICD-10 Finland
Hyperosmolality and hypernatraemia
16.6
13.4
21
12
AXX01, ,
SPAT
3.5
13.3
46
126
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.6
13.3
379
2426
S06.6
ICD-10 Finland
Traumatic subarachnoid haemorrhage
+∞
13.2
13
*
30041
ICD-8 Finland
Neuroses, Depressiva
+∞
13.2
13
*
G40.10
ICD-10 Finland
Simple partial seizures
+∞
13.2
13
*
AAA20
NOMESCO Finland
Insertion of intraventricular pressure monitoring device
+∞
13.2
13
*
G97.0
ICD-10 Finland
Cerebrospinal fluid leak from spinal puncture
+∞
13.2
13
*
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
+∞
13.2
13
*
N05AF05
ATC
zuclopenthixol; systemic
+∞
13.2
13
*
F02.09*G31.0
ICD-10 Finland
Dementia in Pick's disease without information on additional symptoms
+∞
13.2
13
*
F31.7
ICD-10 Finland
Bipolar affective disorder, currently in remission
+∞
13.2
13
*
2900A
ICD-9 Finland
Senile and presenile organic psychotic conditions, Senile dementia, uncomplicated
+∞
13.2
13
*
I63.5
ICD-10 Finland
Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
+∞
13.2
13
*
F01.29
ICD-10 Finland
Subcortical vascular dementia without information on additional symptoms
71.2
13.2
15
*
A10AE05
ATC
insulin detemir; parenteral
2.5
13.2
82
314
F10.09
ICD-10 Finland
Alcohol intoxication UNS
132.7
13.1
14
*
SPAT1262
SPAT
Handing over of treatment supplies
1.7
13.1
258
1505
N18
ICPC
Paralysis/weakness
12.2
12.9
23
18
N39.4
ICD-10 Finland
Other specified urinary incontinence
2.1
12.8
128
600
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
37.9
12.8
16
*
SPAT1100
SPAT
Long-term monitoring of blood pressure
2.0
12.8
137
659
SPAT1276
SPAT
Outlining of treatment with patient or their family members
3.4
12.8
45
125
G56.2
ICD-10 Finland
Lesion of ulnar nerve
11.5
12.6
23
19
R32
ICD-10 Finland
Unspecified urinary incontinence
3.3
12.5
48
141
F21, ,
ICPC
5.6
12.5
24
41
N03AX16
ATC
[U] pregabalin
1.7
12.4
258
1526
I63.1
ICD-10 Finland
Cerebral infarction due to embolism of precerebral arteries
+∞
12.2
12
*
F01.19
ICD-10 Finland
Multi-infarct dementia without information on additional symptoms
+∞
12.2
12
*
3310A
ICD-9 Finland
Other cerebral degenerations, Alzheimer's disease
+∞
12.2
12
*
2968A
ICD-9 Finland
Affective psychoses, Manic-depressive psychosis, other and unspecified
+∞
12.2
12
*
J01DA01
ATC
[U] cefalexin
1.4
12.0
1022
8051
R41
ICD-10 Finland
Other symptoms and signs involving cognitive functions and awareness
8.8
11.9
25
27
E0000UV, ,
ATC
1.5
11.9
574
4091
H02AA02
ATC
fludrocortisone; oral
6.0
11.9
21
33
N05AC02
ATC
thioridazine; oral
11.0
11.8
22
19
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
11.8
270
1635
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.5
11.7
441
2993
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.5
11.7
432
2920
A06AC01
ATC
ispaghula (psylla seeds); oral
1.5
11.6
388
2567
A01
ICPC
Pain general/multiple sites
2.1
11.6
113
525
S01.1
ICD-10 Finland
Open wound of eyelid and periocular area
3.6
11.5
38
101
Z28
ICPC
Limited function/disability (Z)
11.1
11.4
21
18
SPAT1221
SPAT
Guidance concerning rehabilitation services and livelihood
5.5
11.3
22
38
F06.9
ICD-10 Finland
Unspecified mental disorder due to brain damage and dysfunction and to physical disease
61.5
11.3
13
*
S01.9
ICD-10 Finland
Open wound of head, part unspecified
4.3
11.3
29
64
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
28.4
11.3
15
5
F10.20
ICD-10 Finland
Alcohol dependence currently independent
28.4
11.3
15
5
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
28.4
11.3
15
5
G40
ICD-10 Finland
Epilepsy
+∞
11.2
11
*
3540A
ICD-9 Finland
Mononeuritis of upper limb and mononeuritis multiplex, Carpal tunnel syndrome
+∞
11.2
11
*
N04BA03
ATC
levodopa, decarboxylase inhibitor and COMT inhibitor; oral
+∞
11.2
11
*
N07AA06, ,
ATC
+∞
11.2
11
*
G21.9
ICD-10 Finland
Secondary parkinsonism, unspecified
+∞
11.2
11
*
N19
ICPC
Speech disorder
21.7
11.2
16
7
G04CA02
ATC
tamsulosin; oral
1.5
11.2
465
3213
D07AA02
ATC
hydrocortisone; topical
1.8
11.2
185
1025
AAF00
NOMESCO Finland
Ventriculostomy
113.7
11.2
12
*
A10AB04
ATC
insulin lispro; parenteral
3.4
11.1
39
108
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.4
11.1
79
322
S22.3
ICD-10 Finland
Fracture of rib
2.1
11.0
99
446
G03CA04
ATC
estriol; systemic, vaginal
1.8
11.0
164
882
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
11.0
449
3093
R50.9
ICD-10 Finland
Fever, unspecified
1.7
10.8
214
1247
R23.8
ICD-10 Finland
Other and unspecified skin changes
0.5
10.7
98
1780
T90.5
ICD-10 Finland
Sequelae of intracranial injury
41.0
10.6
13
*
WX402
NOMESCO Finland
General anaesthesia
0.5
10.6
80
1553
A10AC01
ATC
insulin (human); parenteral
1.8
10.5
149
788
W06
ICD-10 Finland
Fall involving bed
5.6
10.5
20
34
N06AX05
ATC
trazodone; oral
5.6
10.5
20
34
S00.0
ICD-10 Finland
Superficial injury of scalp
3.4
10.4
37
104
F01.20
ICD-10 Finland
Subcortical vascular dementia without additional symptoms
20.3
10.3
15
7
NA1AD
NOMESCO Finland
Cervical spine CT examination
3.0
10.3
44
138
3039X
ICD-9 Finland
Alcohol dependence syndrome, Other and unspecified alcohol dependence
+∞
10.2
10
*
WX780
NOMESCO Finland
Remote monitoring CPAP
+∞
10.2
10
*
F009, F03,
ICD-10 Finland
+∞
10.2
10
*
F0001, G301,
ICD-10 Finland
+∞
10.2
10
*
F0011, G301,
ICD-10 Finland
+∞
10.2
10
*
AA7AA
NOMESCO Finland
Liquor cerebri shunt X-ray examinatin without contrast
+∞
10.2
10
*
G40.19
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
+∞
10.2
10
*
F00, F03,
ICD-10 Finland
+∞
10.2
10
*
F31.4
ICD-10 Finland
Bipolar affective disorder, current episode severe depression without psychotic symptoms
+∞
10.2
10
*
IGY01
NOMESCO Finland
Accelerated psychiatric treatment contact
104.2
10.2
11
*
F31.30
ICD-10 Finland
Bipolar disorder Depressive episode without somatic syndrome
104.2
10.2
11
*
ICC04
NOMESCO Finland
Psychiatric treatment plan, permanent discontinuation
104.2
10.2
11
*
F41.1
ICD-10 Finland
Generalized anxiety disorder
10.6
10.1
19
17
NF1AA
NOMESCO Finland
Hip X-ray examination
1.8
10.1
147
785
L01BC06
ATC
capecitabine; oral
0.2
10.1
8
423
R51
ICD-10 Finland
Headache
3.2
10.0
39
116
T89
ICPC
Diabetes insulin dependent
3.2
10.0
39
116
A03FA01
ATC
metoclopramide; systemic, rectal
0.6
9.9
180
2680
A02BC03
ATC
lansoprazole; oral
1.4
9.9
461
3249
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
4.3
9.8
25
55
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.6
9.8
254
1584
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
0.5
9.8
100
1752
C34.1
ICD-10 Finland
Malignant neoplasm: Upper lobe, bronchus or lung
0.2
9.7
7
396
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
2.6
9.6
56
208
L82
ICD-10 Finland
Seborrhoeic keratosis
0.5
9.6
102
1768
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
2.0
9.6
98
464
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.9
9.5
44
145
ZXY02
NOMESCO Finland
Neuropsychologist
52.1
9.4
11
*
N05CD08
ATC
midazolam; nasal, systemic
2.8
9.3
46
157
SPAT1243
SPAT
Psychiatric/psychological examination
12.6
9.3
16
12
8070/3-C34.9
ICD-O-3
Squamous cell carcinoma, NOS, of lung, NOS
0.1
9.3
*
278
K92.0
ICD-10 Finland
Haematemesis
2.5
9.3
57
218
Y94.0
ICD-10 Finland
Accident at home
3.5
9.2
31
84
PAF14
NOMESCO Finland
Thrombendarterectomy of internal carotid artery
94.6
9.2
10
*
F01.0
ICD-10 Finland
Vascular dementia of acute onset
94.6
9.2
10
*
I63.8
ICD-10 Finland
Other cerebral infarction
+∞
9.2
9
*
183
Kela drug reimbursment
Lamotrigin and topiramate
+∞
9.2
9
*
N03AX18
ATC
lacosamide; systemic
+∞
9.2
9
*
F25.9
ICD-10 Finland
Schizoaffective disorder, unspecified
+∞
9.2
9
*
G40.21
ICD-10 Finland
Partial epileptic seizure with cloudiness and automatism
+∞
9.2
9
*
30040
ICD-8 Finland
Neuroses, Neurotico-depressiva
+∞
9.2
9
*
AAC00
NOMESCO Finland
Ligature of intracranial aneurysm
+∞
9.2
9
*
ACC53
NOMESCO Finland
Release of ulnar nerve
+∞
9.2
9
*
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
8.6
9.1
19
21
P15
ICPC
Chronic alcohol abuse
8.6
9.1
19
21
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.0
9.1
98
473
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
0.2
9.1
7
378
N99
ICPC
Neurological disease other
16.6
9.1
14
8
SPAT1157
SPAT
Guidance concerning treatment of mouth and mucous membranes
3.8
9.1
27
67
OAB93, ,
SPAT
3.6
9.0
29
76
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
9.0
591
4407
SCA02
NOMESCO Finland
Preventive oral health care
2.0
8.9
98
477
W00
ICD-10 Finland
Fall on same level involving ice and snow
1.8
8.9
137
744
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
9.0
8.9
18
19
R33
ICD-10 Finland
Retention of urine
1.7
8.9
163
931
I95.9
ICD-10 Finland
Hypotension, unspecified
3.6
8.9
29
77
SPAT1014
SPAT
Treatment of eyes
3.1
8.9
36
110
H81.9
ICD-10 Finland
Disorder of vestibular function, unspecified
4.7
8.8
20
40
R4130
NOMESCO Finland
Speech therapy
4.0
8.8
25
60
E11.4
ICD-10 Finland
Type 2 diabetes mellitus, with neurological complications
3.6
8.8
28
73
F99
ICD-10 Finland
Mental disorder, not otherwise specified
34.7
8.8
11
*
G04BD08
ATC
solifenacin; oral
2.0
8.7
101
500
SPAT1285
SPAT
Provision of consultation response
2.2
8.7
72
314
ZXD05
NOMESCO Finland
Urgent procedure
1.4
8.7
448
3203
AA1CG, ,
SPAT
9.5
8.7
17
17
ZXE10
NOMESCO Finland
More than one and less than three hours
1.4
8.6
548
4057
R5140
NOMESCO Finland
Monitoring the use of the aid
2.2
8.6
69
297
R54
ICD-10 Finland
Senility
4.9
8.6
19
37
-2, ,
ICPC
4.9
8.6
19
37
K86
ICPC
Hypertension uncomplicated
0.5
8.6
76
1398
KMAK, ,
NOMESCO Finland
1.4
8.6
559
4155
G51.0
ICD-10 Finland
Bell palsy
11.9
8.5
15
12
R06.5
ICD-10 Finland
Mouth breathing
2.5
8.5
52
199
G04CB01
ATC
finasteride; oral
1.5
8.4
243
1550
F33.4
ICD-10 Finland
Recurrent depressive disorder, currently in remission
47.3
8.4
10
*
F22.9
ICD-10 Finland
Persistent delusional disorder, unspecified
47.3
8.4
10
*
2402
FHL
External neurolysis of the nerve and possible alteration of the pathway (nerve pressure)
8.1
8.4
18
21
A99
ICPC
Disease/condition unspecnature/site
1.8
8.4
124
665
A10BB12
ATC
glimepiride; oral
1.7
8.4
166
967
S00.1
ICD-10 Finland
Contusion of eyelid and periocular area
3.4
8.3
30
85
N02AJ06
ATC
codeine and paracetamol; systemic
0.7
8.3
246
3296
R07.4
ICD-10 Finland
Chest pain, unspecified
1.4
8.3
371
2586
K91
ICPC
Cerebrovascular disease
15.4
8.3
13
8
A04AA01
ATC
ondansetron; systemic, rectal
0.3
8.2
28
762
Z60.9
ICD-10 Finland
Problem related to social environment, unspecified
26.0
8.2
11
*
N04BC04
ATC
ropinirole; oral
85.2
8.2
9
*
G91.9
ICD-10 Finland
Hydrocephalus, unspecified
85.2
8.2
9
*
G44.0
ICD-10 Finland
Cluster headache syndrome
85.2
8.2
9
*
TAB22
NOMESCO Finland
Stoppin epidural fluid escape with coagulated blood
85.2
8.2
9
*
XA400
NOMESCO Finland
EEG
18.9
8.2
12
6
Z75.0
ICD-10 Finland
Medical services not available in home
18.9
8.2
12
6
F32.8
ICD-10 Finland
Other depressive episodes
18.9
8.2
12
6
R05FB02
ATC
cough suppressants and expectorants; systemic
1.3
8.2
645
4931
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
9.5
8.2
16
16
30320
ICD-8 Finland
Alcoholism, Alcoholic addiction
+∞
8.1
8
*
29599
ICD-8 Finland
Schizophrenia, Unspecified type
+∞
8.1
8
*
F10.9
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Unspecified mental and behavioural disorder
+∞
8.1
8
*
F00.03
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenil onset other additional symptoms, mainly depression
+∞
8.1
8
*
3004A
ICD-9 Finland
Neurotic disorders, Neurotic depression
+∞
8.1
8
*
F00.13
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset other additional symptoms, mainly depression
+∞
8.1
8
*
F31.1
ICD-10 Finland
Bipolar affective disorder, current episode manic without psychotic symptoms
+∞
8.1
8
*
G47.0
ICD-10 Finland
Disorders of initiating and maintaining sleep [insomnias]
+∞
8.1
8
*
G31.2
ICD-10 Finland
Degeneration of nervous system due to alcohol
+∞
8.1
8
*
N88
ICPC
Epilepsy
+∞
8.1
8
*
ICB03
NOMESCO Finland
Psychiatric treatment plan, monitoring
+∞
8.1
8
*
F0003, G300,
ICD-10 Finland
+∞
8.1
8
*
I61.1
ICD-10 Finland
Intracerebral haemorrhage in hemisphere, cortical
+∞
8.1
8
*
F31.8
ICD-10 Finland
Other bipolar affective disorders
+∞
8.1
8
*
F0002, G300,
ICD-10 Finland
+∞
8.1
8
*
F20.09
ICD-10 Finland
Paranoid schizophrenia UNS
+∞
8.1
8
*
F33.30
ICD-10 Finland
Recurrent depression, severe episode without somatic syndrome
+∞
8.1
8
*
R40.2
ICD-10 Finland
Coma, unspecified
6.5
8.1
20
29
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
4.1
8.1
22
51
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
1.7
8.1
159
926
SCA01
NOMESCO Finland
Preventive oral health care, short
1.5
8.0
267
1756
A08.4
ICD-10 Finland
Viral intestinal infection, unspecified
3.1
8.0
32
97
M01AX01
ATC
nabumetone; oral
2.2
7.9
65
283
M03BX01
ATC
baclofen; systemic
8.9
7.9
16
17
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.4
7.9
511
3785
K59.0
ICD-10 Finland
Constipation
2.0
7.9
89
437
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
4.0
7.9
22
52
N07BB01
ATC
disulfiram; oral
4.2
7.9
21
48
JN4AD
NOMESCO Finland
Body CT examination
0.4
7.8
40
903
Z03.2
ICD-10 Finland
Observation for suspected mental and behavioural disorders
16.2
7.8
12
7
N03AX11
ATC
topiramate; oral
11.1
7.8
14
12
Z03
ICPC
Housing/neighbourhood problem
11.1
7.8
14
12
P99
ICPC
Psychological disorders other
9.5
7.7
15
15
R25.1
ICD-10 Finland
Tremor, unspecified
3.3
7.7
28
80
SPAT1260
SPAT
Consultation of another employee
1.5
7.7
221
1409
A03FA02
ATC
cisapride; oral, rectal
1.7
7.7
130
727
R13
ICD-10 Finland
Dysphagia
2.0
7.6
79
377
Z75.1
ICD-10 Finland
Person awaiting admission to adequate facility elsewhere
3.0
7.6
33
105
ZXD35
NOMESCO Finland
Usual procedure
2.4
7.6
49
192
S18
ICPC
Laceration/cut
0.7
7.6
383
4672
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.5
7.6
226
1452
G25.0
ICD-10 Finland
Essential tremor
3.8
7.6
23
58
J01FA06
ATC
roxithromycin; oral
1.3
7.6
603
4608
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
0.6
7.5
165
2362
M01AB55
ATC
diclofenac, combinations; oral
1.8
7.5
115
625
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
14.2
7.4
12
8
N06AX18
ATC
reboxetine; oral
14.2
7.4
12
8
A05
ICPC
Feeling ill
2.4
7.4
51
206
D07CA01
ATC
hydrocortisone and antibiotics; topical
1.6
7.4
180
1104
V700A
ICD-9 Finland
General medical examination, Routine general medical examination at a health care facility
2.8
7.4
37
128
N05AC01
ATC
periciazine; systemic
17.4
7.4
11
6
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
17.4
7.4
11
6
M01AC06
ATC
meloxicam; systemic, rectal
1.4
7.3
489
3635
A02BC01
ATC
omeprazole; systemic
1.4
7.3
434
3168
WF049
NOMESCO Finland
Radiotherapy of metastasis
0.2
7.3
8
349
Z08
ICPC
Social welfare problem
7.6
7.3
16
20
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
2.1
7.3
71
332
SPAT1309
SPAT
Guidance related to psychoactive substances / risk behaviour
4.0
7.2
20
47
L57.0
ICD-10 Finland
Actinic keratosis
0.5
7.2
87
1454
SPAT1111
SPAT
Planning of analgesia
3.6
7.2
23
60
AXX01
NOMESCO Finland
Memory assessment
75.7
7.2
8
*
S06.9
ICD-10 Finland
Intracranial injury, unspecified
75.7
7.2
8
*
F32.01
ICD-10 Finland
Mild depressive episode with somatic syndrome
75.7
7.2
8
*
I25.0
ICD-10 Finland
Atherosclerotic cardiovascular disease, so described
1.7
7.2
130
739
4912B
ICD-9 Finland
Chronic bronchitis, Obstructive chronic bronchitis[BRONCHITIS OBSTRUCTIVA CUM EMPHYSEMATE]
0.1
7.2
*
247
XF606
NOMESCO Finland
Ortostatic test
8.4
7.2
15
17
SPAT1215
SPAT
Assessment of need for medical rehabilitation
2.6
7.2
42
157
4359X
ICD-9 Finland
Transient cerebral ischaemia, Unspecified transient cerebral ischaemia
+∞
7.1
7
*
G40.89
ICD-10 Finland
Other epilepsy
+∞
7.1
7
*
2989X
ICD-9 Finland
Other nonorganic psychoses, Unspecified psychosis
+∞
7.1
7
*
F0009, G301,
ICD-10 Finland
+∞
7.1
7
*
F20.30
ICD-10 Finland
Undifferentiated schizophrenia continuous
+∞
7.1
7
*
3050A
ICD-9 Finland
Nondependent abuse of drugs, Alcohol abuse
+∞
7.1
7
*
F00.21
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type of other additional symptoms, mainly paranoidism
+∞
7.1
7
*
Q90.9
ICD-10 Finland
Down syndrome, unspecified
+∞
7.1
7
*
N05AL01
ATC
sulpiride; systemic
6.1
7.0
18
28
J01XX05
ATC
methenamine; oral
3.0
7.0
30
95
S00.9
ICD-10 Finland
Superficial injury of head, part unspecified
4.3
7.0
18
40
K08.3
ICD-10 Finland
Retained dental root
1.8
7.0
95
498
A10AD05
ATC
insulin aspart; parenteral
2.4
6.9
46
183
M02AA10
ATC
ketoprofen; topical
1.5
6.9
227
1487
P04
ICPC
Feeling/behaving irritable/angry
28.4
6.9
9
*
F10.24
ICD-10 Finland
Alcohol depence active use
28.4
6.9
9
*
Z60.8
ICD-10 Finland
Other problems related to social environment
28.4
6.9
9
*
D07CC01
ATC
betamethasone and antibiotics; topical
1.6
6.9
166
1016
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
1.9
6.9
82
411
A02BC05
ATC
esomeprazole; systemic
1.3
6.9
529
4010
NE1AA
NOMESCO Finland
Pelvis X-ray examination
1.7
6.9
111
612
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.7
6.9
136
794
M02AA07
ATC
piroxicam; topical
1.3
6.8
597
4612
P05
ICPC
Senility, feeling/behaving old
6.2
6.8
17
26
PA7BD
NOMESCO Finland
CT angiography of neck and brain
8.3
6.8
14
16
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
0.2
6.8
6
294
M50.3
ICD-10 Finland
Other cervical disc degeneration
3.4
6.7
24
68
J01DA09
ATC
[U] cefadroxil
1.4
6.7
358
2566
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.3
6.6
542
4143
K03.66
ICD-10 Finland
Tooth plaque
1.9
6.6
79
397
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
2.0
6.6
72
351
Z74.2
ICD-10 Finland
Need for assistance at home and no other household member able to render care
37.8
6.6
8
*
Z74.1
ICD-10 Finland
Need for assistance with personal care
37.8
6.6
8
*
F10.25
ICD-10 Finland
Alcohol dependence continuous use
37.8
6.6
8
*
G25.9
ICD-10 Finland
Extrapyramidal and movement disorder, unspecified
15.8
6.5
10
6
AA5BD
NOMESCO Finland
CT of cerebral ischaemia
15.8
6.5
10
6
SPAT1125
SPAT
Stoma care and guidance
2.6
6.5
37
137
SPAT1153
SPAT
Removal of sutures
0.7
6.4
247
3166
W18
ICD-10 Finland
Other fall on same level
5.8
6.4
17
28
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.7
6.4
122
705
8000/3-C34.9
ICD-O-3
Neoplasm, malignant of lung, NOS
0.2
6.4
8
323
D07BA04
ATC
hydrocortisone and antiseptics; topical
1.7
6.4
124
720
SPAT1138
SPAT
Guidance concerning bowel function
3.1
6.4
26
80
WZC30
NOMESCO Finland
Teaching
0.5
6.4
77
1285
N06AB08
ATC
fluvoxamine; oral
3.3
6.3
23
66
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.4
6.3
379
2767
S32.8
ICD-10 Finland
Fracture of other and unspecified parts of lumbar spine and pelvis
3.1
6.3
25
76
F06.0
ICD-10 Finland
Organic hallucinosis
66.0
6.3
7
*
G72.9
ICD-10 Finland
Myopathy, unspecified
66.0
6.3
7
*
Z10.1
ICD-10 Finland
Routine general health check-up of inhabitants of institutions
66.0
6.3
7
*
IBZ01
NOMESCO Finland
Profession-specific psychiatric evaluation
66.0
6.3
7
*
SPAT1295
SPAT
Other function in accordance with physical therapy nomenclature
2.1
6.2
54
242
C03CA01
ATC
furosemide; systemic
1.3
6.2
730
5845
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.0
6.2
65
313
N06AX22
ATC
agomelatine; oral
13.5
6.2
10
7
F32.0
ICD-10 Finland
Mild depressive episode
4.0
6.2
17
40
M01AH01
ATC
celecoxib; oral
1.4
6.1
244
1660
3074A
ICD-9 Finland
Special symptoms or syndromes not elsewhere classified, Specific disorders of sleep of nonorganic origin[UNIHÄIRIÖ]
+∞
6.1
6
*
I63.2
ICD-10 Finland
Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
+∞
6.1
6
*
F00.24
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type other additional symptoms of mixed type
+∞
6.1
6
*
ICZ03
NOMESCO Finland
Participation in compiling a psychiatric treatment plan
+∞
6.1
6
*
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
+∞
6.1
6
*
G40.09
ICD-10 Finland
Other or unspecified partial (focal) idiopathic epilepsy or epileptic syndrome with local onset
+∞
6.1
6
*
F30.9
ICD-10 Finland
Manic episode, unspecified
+∞
6.1
6
*
35701
ICD-8 Finland
Other diseases of peripheral nerves except autonomic, Nervi mediani
+∞
6.1
6
*
G21.1
ICD-10 Finland
Other drug-induced secondary parkinsonism
+∞
6.1
6
*
IBA04
NOMESCO Finland
Extensive initial psychiatric evaluation
+∞
6.1
6
*
F002, G308,
ICD-10 Finland
+∞
6.1
6
*
F31.6
ICD-10 Finland
Bipolar affective disorder, current episode mixed
+∞
6.1
6
*
F07.9
ICD-10 Finland
Unspecified organic personality and behavioural disorder due to brain disease, damage and dysfunction
+∞
6.1
6
*
N05BA09
ATC
clobazam; oral
+∞
6.1
6
*
F10.73
ICD-10 Finland
Residual or late-onset psychosis caused by alcohol dementia
+∞
6.1
6
*
F00.23
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type of other additional symptoms, mainly depression
+∞
6.1
6
*
F0010, G300,
ICD-10 Finland
+∞
6.1
6
*
I60.1
ICD-10 Finland
Subarachnoid haemorrhage from middle cerebral artery
+∞
6.1
6
*
F0019, G300,
ICD-10 Finland
+∞
6.1
6
*
WX723
NOMESCO Finland
CPAP therapy
+∞
6.1
6
*
G46.3*I67.9
ICD-10 Finland
Brain stem stroke syndrome (I60-I67+)
+∞
6.1
6
*
F009, G300,
ICD-10 Finland
+∞
6.1
6
*
ZYB04
NOMESCO Finland
Outreach service in patient’s home or everyday environment
+∞
6.1
6
*
F0024, G308,
ICD-10 Finland
+∞
6.1
6
*
F01.10
ICD-10 Finland
Multi-infarct dementia without additional symptoms
+∞
6.1
6
*
AAF20
NOMESCO Finland
Revision of shunt of ventricle of brain
+∞
6.1
6
*
G21.0
ICD-10 Finland
Malignant neuroleptic syndrome
+∞
6.1
6
*
G41.0
ICD-10 Finland
Grand mal status epilepticus
+∞
6.1
6
*
F0023, G308,
ICD-10 Finland
+∞
6.1
6
*
30300
ICD-8 Finland
Alcoholism, Episodic excessive drinking
+∞
6.1
6
*
NFB10
NOMESCO Finland
Primary partial prosthetic replacement of hip joint not using cement, other or unspecified
5.0
6.1
18
34
C05AA08
ATC
fluocortolone; rectal, topical
1.5
6.1
181
1163
R40.0
ICD-10 Finland
Somnolence
17.0
6.1
9
5
3639
FHL
Other measure in this category
7.7
6.1
13
16
P27
ICPC
Fear of mental disorder
25.2
6.0
8
*
F43.29
ICD-10 Finland
Adaptation disorder UNS
8.7
6.0
12
13
R47.8
ICD-10 Finland
Other and unspecified speech disturbances
8.7
6.0
12
13
WW200, ,
SPAT
0.6
6.0
141
1990

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
224
36
65.84
307.65
1.2
1.2
124.42
47.68
e6/l
1.25
179
28
224
36
65.84
307.65
1.1
1.1
2.26
17.75
e6/l
0.54
171
28
227
44
54.66
307.65
1.1
1.1
3.75
3.62
mmol/l
0.53
216
39
180
42
44.24
286.77
1.1
1.1
—
—
—
0
0
104
12
86.03
186.64
1.2
1.1
—
—
—
0
0
74
23
31.42
108.24
1.1
1.0
—
—
—
0
0
553
2143
2.97
93.35
1.8
1.7
1203.53
1129.71
nmol/l
1.07
397
1561
859
10734
0.57
32.27
3.9
4.2
1.50
1.50
mmol/l
0.13
749
9502
874
10857
0.57
31.94
3.9
4.2
4.56
4.64
mmol/l
1.27
771
9702
914
11185
0.58
31.10
4.3
4.7
2.66
2.72
mmol/l
1.10
797
9914
435
2346
1.95
30.31
1.7
1.7
445.81
17631582.97
pmol/l
1.25
357
1849
828
10353
0.58
29.99
3.5
3.8
1.20
1.24
mmol/l
1.05
711
9078
445
2482
1.88
27.74
2.5
1.7
281.16
180.63
u/l
1.96
406
2231
704
4621
1.67
24.46
2.1
1.9
96.86
92.07
pmol/l
1.62
351
2238
297
4578
0.54
20.53
1.9
2.2
—
—
—
0
0
633
4196
1.61
20.32
4.1
3.6
62.42
73.65
ng/l
0.31
459
3163
576
3743
1.63
19.99
2.1
3.6
2.35
2.35
mmol/l
0.57
472
3176
409
2452
1.72
19.23
1.5
1.5
20.33
19.87
nmol/l
0.24
353
2026
363
2149
1.72
17.73
2.4
3.2
2.44
2.47
mmol/l
7.53
288
1810
377
2267
1.70
17.36
5.4
3.8
1.02
1.02
kg/l
0.73
57
377
22
7
29.91
16.53
1.5
1.4
—
—
—
0
0
48
123
3.74
15.27
1.7
2.6
31.24
36.84
umol/l
0.51
42
106
981
11010
0.69
15.07
4.2
4.5
6.20
6.01
mmol/l
2.31
842
9651
28
24
11.13
14.94
1.4
1.0
—
—
—
0
0
959
7323
1.45
14.39
5.7
4.2
2024.35
2816.63
e6/l
0.22
40
113
225
3433
0.57
14.08
3.0
3.0
—
—
—
0
0
12
0
+∞
12.23
14.2
0.0
718.50
—
nmol/l
—
12
0
172
909
1.86
12.16
3.7
3.0
—
—
—
0
0
47
1194
0.36
11.95
1.3
1.4
—
—
—
0
0
665
4871
1.43
11.85
3.4
4.4
34.88
34.14
g/l
2.39
575
4423
932
10330
0.72
11.58
5.9
5.7
42.44
40.48
mmol/mol
4.72
795
9228
52
168
2.97
11.56
1.1
1.2
—
—
—
0
0
532
3755
1.46
11.53
3.7
3.1
—
—
—
0
0
270
3758
0.63
11.33
3.3
3.6
7.02
8.41
mg/mmol
0.23
165
2311
246
3492
0.62
11.23
2.8
3.1
50.27
278.77
mg/l
3.03
153
2153
478
3320
1.47
11.22
3.8
3.9
—
—
—
0
0
176
2696
0.58
10.87
1.5
1.6
1.28
1.28
mmol/l
0.03
150
2189
380
4864
0.67
10.54
8.5
9.0
0.00
0.00
e9/l
0.26
294
3887
87
1632
0.48
10.46
1.3
1.4
—
—
—
0
0
256
3524
0.64
10.06
2.6
2.9
7.14
6.90
mmol/l
0.42
192
2844
221
1334
1.63
9.74
1.6
2.0
29.51
30.63
s
1.95
212
1285
404
2786
1.46
9.68
5.1
3.8
0.00
0.00
estimate
0.50
73
874
196
2840
0.61
9.60
1.2
1.3
—
—
—
0
0
17
14
11.52
9.48
1.1
1.1
127.65
145.07
nmol/l
0.40
17
14
420
5181
0.70
9.27
2.3
2.5
—
—
—
0
0
727
5598
1.35
8.98
4.9
6.0
1.22
1.21
mmol/l
5.02
604
4686
69
1328
0.47
8.90
1.2
1.2
6.02
18.62
u/ml
2.29
24
466
873
9507
0.76
8.10
19.1
17.2
15.22
15.12
%
0.21
829
9233
93
1552
0.54
7.71
2.2
4.2
16.13
24.23
ug/l
0.31
76
1305
730
8107
0.76
7.66
3.8
3.8
—
—
—
0
0
1149
12012
0.77
7.50
7.9
9.6
22.97
24.33
u/l
1.06
1051
11361
167
1006
1.61
7.42
2.6
2.3
6.82
6.81
ug/l
0.00
112
852
22
56
3.73
7.17
3.4
2.9
—
—
—
0
0
543
4144
1.32
6.73
4.4
3.3
5.82
5.83
ph
0.01
17
212
644
5037
1.30
6.66
4.6
5.3
1.22
1.21
mmol/l
2.10
552
4532
88
1429
0.56
6.63
1.2
1.2
19.88
43.73
iu/ml
2.65
26
464
59
269
2.10
6.48
2.0
2.4
1452.82
364.94
ug/l
1.12
52
259
340
2445
1.37
6.21
5.0
3.3
—
—
—
0
0
10
7
13.51
6.17
1.2
1.0
—
—
—
0
0
422
4933
0.75
6.07
5.1
5.4
59.94
58.82
%
0.99
375
4516
27
89
2.88
5.92
1.1
1.1
358.81
333.73
nmol/l
0.23
22
66
42
814
0.47
5.58
1.4
1.5
—
—
—
0
0
188
2468
0.69
5.55
2.7
3.2
0.98
0.92
ug/l
0.13
129
1746
533
4168
1.28
5.31
1.9
2.0
77.84
80.47
nmol/l
1.09
431
3603
413
4762
0.77
5.22
4.6
5.4
0.63
0.65
%
0.33
363
4346
441
5040
0.77
5.20
5.0
5.6
25.37
25.86
%
0.39
390
4625
415
4770
0.77
5.10
4.5
5.8
—
—
—
0
0
236
2938
0.72
5.09
2.1
2.7
2852.48
7877.72
umol/l
1.79
192
2476
428
4896
0.78
5.06
4.9
5.4
2.80
2.83
%
0.08
378
4471
65
1058
0.56
4.97
1.2
1.2
515.56
517.93
titre
—
9
232
470
5301
0.78
4.93
5.2
5.2
1.71
1.83
e9/l
1.84
389
4540
432
4916
0.78
4.87
5.4
5.7
8.62
8.92
%
0.88
385
4493
13
24
5.13
4.66
1.2
1.0
—
—
—
0
0
10
13
7.27
4.64
2.8
1.7
39190.00
26222.15
ug/l
—
10
13
458
5151
0.79
4.64
5.1
5.1
0.58
0.62
e9/l
2.23
377
4280
91
534
1.63
4.59
2.4
3.9
7.43
7.40
ph
—
7
59
566
6203
0.80
4.53
7.0
8.4
4.47
4.29
e9/l
0.87
472
5269
479
5331
0.80
4.38
5.2
5.2
0.18
0.20
e9/l
1.13
391
4492
91
541
1.61
4.37
2.4
3.9
5.16
5.11
kpa
0.29
80
504
59
312
1.80
4.33
2.6
4.1
24.27
24.41
mmol/l
0.14
52
269
463
5165
0.80
4.31
5.1
5.1
0.04
0.04
e9/l
2.25
380
4287
221
2707
0.74
4.25
2.1
2.4
—
—
—
0
0
638
5217
1.22
4.10
4.6
3.6
0.00
0.00
estimate
0.50
91
1033
763
6352
1.21
4.09
4.4
3.9
7.17
6.85
mmol/l
2.44
690
5928
314
3622
0.78
3.84
2.1
2.4
—
—
—
0
0
27
113
2.27
3.77
30.0
6.9
7.90
7.11
mmol/l
0.56
20
91
672
5570
1.20
3.69
15.9
18.6
1.33
1.49
inr
1.40
156
1510
67
387
1.65
3.65
2.4
3.9
—
—
—
0
0
18
405
0.41
3.64
1.5
1.4
—
—
—
0
0
10
19
4.98
3.63
1.2
1.0
1726.90
1931.63
miu/ml
—
10
19
8
236
0.32
3.58
1.9
1.4
—
—
—
0
0
148
1875
0.72
3.54
3.0
2.8
3.17
2.85
e6/l
0.15
82
1071
129
1666
0.71
3.47
2.1
2.4
21.55
21.27
%
0.08
90
1421
407
3228
1.24
3.44
2.2
2.3
58.70
63.55
u/l
0.57
366
2952
52
809
0.59
3.43
2.3
3.8
0.86
0.71
%
0.08
14
281
60
901
0.62
3.43
2.5
3.8
2.24
0.95
%
0.45
19
325
631
5244
1.19
3.30
6.0
5.0
0.00
0.00
estimate
-0.00
81
916
13
40
3.07
3.27
1.2
1.2
—
—
—
0
0
58
864
0.62
3.22
2.6
3.8
0.12
0.11
%
0.02
17
291
22
432
0.47
3.16
1.1
1.8
—
20.22
—
0
17
29
519
0.52
3.16
1.2
1.4
—
—
—
0
0
0
77
0.00
3.15
0.0
1.3
—
—
—
0
0
885
7597
1.17
3.11
4.7
4.1
—
—
—
0
0
52
788
0.61
3.11
2.6
3.9
0.08
0.14
%
0.23
12
236
635
5309
1.19
3.06
4.7
3.6
0.00
0.00
estimate
0.50
80
927
14
47
2.82
3.06
1.2
1.2
—
—
—
0
0
78
1077
0.67
3.05
4.2
5.5
12.53
12.54
mmol/l
0.00
69
998
31
530
0.54
2.93
1.9
1.8
1.96
1.44
g/l
0.39
24
462
14
49
2.70
2.85
1.2
1.2
—
—
—
0
0
14
49
2.70
2.85
1.2
1.2
—
—
—
0
0
143
1753
0.75
2.78
1.9
2.3
2.19
2.24
g/l
0.48
115
1601
381
4166
0.83
2.75
4.0
5.3
3.57
5.98
ug/l
1.58
325
3662
6
175
0.32
2.68
1.2
1.8
2.35
5.00
mmol/24h
—
6
143
163
1951
0.77
2.67
2.7
2.7
1.71
1.29
e6/l
0.75
96
1141
118
1462
0.75
2.49
4.0
4.7
1.04
1.06
mmol/l
0.30
102
1329
85
1109
0.71
2.49
1.2
1.3
—
—
—
0
0
15
59
2.40
2.46
1.5
1.8
—
—
—
0
0
60
830
0.67
2.43
1.4
1.4
—
—
—
0
0
13
48
2.56
2.42
1.2
1.2
—
—
—
0
0
109
766
1.36
2.39
1.4
1.4
—
—
—
0
0
148
1090
1.30
2.36
4.4
4.0
—
—
—
0
0
52
319
1.55
2.33
3.6
3.2
35.62
28.59
mg/l
0.48
40
212
43
253
1.61
2.29
1.2
1.1
—
—
—
0
0
290
3199
0.83
2.29
3.2
3.1
0.58
0.62
e6/l
0.11
233
2429
7
17
3.89
2.23
1.7
1.3
—
—
—
0
0
405
3342
1.18
2.22
2.5
3.9
7.41
7.40
ph
0.63
63
613
94
657
1.36
2.16
1.6
2.4
415.24
397.55
nmol/l
0.33
74
601
6
159
0.35
2.14
1.0
1.3
—
—
—
0
0
81
1026
0.73
2.02
1.8
2.5
65.42
65.55
g/l
0.05
67
907
6
152
0.37
2.02
1.8
1.2
—
—
—
0
0
16
292
0.51
1.96
1.7
1.5
—
—
—
0
0
127
1504
0.78
1.96
1.5
1.5
2.63
2.72
g/l
0.17
67
844
77
973
0.74
1.91
1.7
2.1
0.19
0.20
g/l
0.38
66
901
44
613
0.67
1.90
1.3
1.2
—
—
—
0
0
13
250
0.49
1.87
1.2
1.1
—
—
—
0
0
22
114
1.83
1.87
1.8
1.9
—
—
—
0
0
47
641
0.68
1.83
3.2
6.5
24.87
24.90
mmol/l
0.02
47
635
12
235
0.48
1.83
1.6
1.6
111.08
262.41
pmol/l
1.78
12
227
17
296
0.54
1.82
1.1
3.1
16.61
988.13
u/ml
1.44
12
277
164
1867
0.81
1.80
1.9
2.3
11.82
11.85
umol/l
0.01
132
1726
48
649
0.69
1.79
1.3
1.6
1.58
1.52
g/l
0.14
30
550
61
412
1.41
1.77
5.8
3.3
—
—
—
0
0
5
129
0.36
1.76
1.2
1.3
0.39
0.74
g/l
—
5
96
5
130
0.36
1.75
1.0
1.1
—
—
—
0
0
15
268
0.52
1.75
1.1
1.3
—
—
—
0
0
31
451
0.64
1.68
1.3
2.1
10.72
10.71
g/l
0.01
25
383
25
381
0.61
1.66
1.3
2.0
38.51
36.85
g/l
0.76
19
318
338
3579
0.87
1.62
4.0
3.8
—
—
—
0
0
16
272
0.55
1.61
1.1
1.4
—
11.91
—
0
7
290
2396
1.16
1.58
2.7
2.5
6.28
5.82
e6/l
0.23
257
2098
46
609
0.70
1.56
8.6
8.1
—
—
—
0
0
10
196
0.48
1.56
1.7
1.4
—
—
—
0
0
7
149
0.44
1.55
2.3
3.5
2.70
48.43
nmol/l
—
7
144
10
42
2.25
1.53
5.4
40.0
—
—
—
0
0
23
346
0.62
1.47
2.3
3.3
—
—
—
0
0
1275
12457
0.90
1.45
23.1
20.5
242.66
243.17
e9/l
0.10
1178
11925
1276
12463
0.90
1.44
23.1
20.7
129.65
132.25
g/l
7.56
1192
12139
1276
12460
0.90
1.42
23.0
20.5
4.30
4.38
e12/l
6.75
1169
11878
1276
12458
0.90
1.41
22.9
20.5
30.31
30.37
pg
0.56
1195
12127
10
188
0.50
1.41
1.7
1.5
—
—
—
0
0
1276
12457
0.90
1.41
23.0
20.5
91.48
91.67
fl
0.75
1196
12126
9
168
0.50
1.40
2.1
2.0
12.04
22.27
ug/l
—
9
161
117
903
1.23
1.37
2.4
2.7
4.18
4.28
kpa
0.22
107
861
1277
12457
0.91
1.36
23.1
20.5
7.06
6.82
e9/l
2.31
1171
11871
353
2992
1.13
1.36
2.1
2.2
3.19
3.15
mg/l
0.10
274
2493
0
35
0.00
1.35
0.0
1.4
—
—
—
0
0
57
708
0.75
1.33
4.0
3.6
—
—
—
0
0
1276
12441
0.91
1.33
23.0
20.7
38.05
39.03
%
4.02
1113
11400
292
3077
0.88
1.31
3.1
3.0
—
—
—
0
0
21
312
0.63
1.30
1.3
1.1
—
—
—
0
0
100
1153
0.81
1.30
2.0
2.7
10.83
10.66
umol/l
0.02
78
997
9
162
0.52
1.30
1.7
1.3
—
—
—
0
0
1217
11034
1.10
1.28
16.9
14.0
31.49
28.75
mg/l
1.32
966
8641
5
17
2.77
1.27
1.6
1.5
—
—
—
0
0
7
137
0.48
1.20
1.6
1.2
—
—
—
0
0
36
470
0.72
1.19
1.2
1.1
56.99
146.60
iu/ml
1.97
18
154
10
175
0.54
1.16
2.0
1.4
—
—
—
0
0
30
402
0.70
1.15
1.6
1.2
—
—
—
0
0
264
2774
0.88
1.15
5.3
6.4
—
—
—
0
0
1181
11518
0.92
1.14
16.3
13.4
—
—
—
0
0
0
34
0.00
1.14
0.0
1.0
—
—
—
0
0
153
1667
0.85
1.11
2.2
2.9
0.83
0.82
mmol/l
0.80
136
1522
12
194
0.58
1.08
1.5
1.9
—
—
—
0
0
5
20
2.36
1.07
1.4
1.2
—
—
—
0
0
50
608
0.77
1.05
5.4
7.9
24.73
24.32
mmol/l
0.46
42
576
22
137
1.52
1.04
2.0
2.0
1.83
1.51
u/field
—
6
39
38
265
1.36
1.01
1.2
1.1
—
—
—
0
0
11
178
0.58
1.00
1.7
2.6
—
—
—
0
0
855
7689
1.08
1.00
3.4
3.5
15.13
15.10
pmol/l
0.08
731
6723
13
200
0.61
0.98
1.8
1.7
—
—
—
0
0
0
28
0.00
0.98
0.0
1.2
—
147.54
—
0
28
99
1104
0.84
0.97
1.9
2.4
62.62
65.80
e9/l
0.48
80
827
12
186
0.61
0.94
1.3
2.7
—
—
—
0
0
8
134
0.56
0.93
1.3
2.2
—
—
—
0
0
6
26
2.18
0.92
1.2
1.3
—
—
—
0
0
11
59
1.76
0.91
1.9
1.7
0.17
4.54
u/field
—
6
39
138
1132
1.16
0.90
1.5
1.7
—
—
—
0
0
9
146
0.58
0.88
1.6
1.4
—
—
—
0
0
7
121
0.54
0.88
1.3
1.2
—
—
—
0
0
7
123
0.53
0.88
1.4
1.1
—
—
—
0
0
70
795
0.82
0.85
1.8
2.4
—
—
—
0
0
18
113
1.50
0.85
1.1
1.0
—
—
—
0
0
11
167
0.62
0.81
1.0
1.0
—
—
—
0
0
202
2105
0.89
0.81
1.5
1.5
1.78
1.63
mg/l
0.10
138
1618
0
23
0.00
0.79
0.0
1.2
—
—
—
0
0
0
24
0.00
0.79
0.0
1.1
—
—
—
0
0
0
24
0.00
0.79
0.0
1.2
—
—
—
0
0
0
24
0.00
0.79
0.0
1.1
—
—
—
0
0
0
24
0.00
0.79
0.0
1.1
—
—
—
0
0
14
199
0.66
0.78
1.1
1.2
—
121.25
—
0
8
41
487
0.79
0.77
1.2
1.3
—
—
—
0
0
132
1096
1.14
0.76
2.5
3.3
1.95
2.06
mmol/l
0.12
108
867
35
254
1.30
0.76
1.2
1.4
294.64
269.46
ug/g
0.33
22
152
15
207
0.68
0.74
1.1
1.2
—
1468.33
—
0
6
14
86
1.54
0.73
1.3
1.3
281.60
274.52
mosm/kgh2o
—
5
63
11
162
0.64
0.73
1.2
1.2
—
—
—
0
0
264
2694
0.91
0.72
3.1
3.6
85.82
84.30
%
0.38
251
2628
131
1096
1.13
0.69
2.5
3.3
5.80
5.80
kpa
0.01
122
1048
11
65
1.60
0.68
4.8
3.4
—
—
—
0
0
60
672
0.84
0.67
2.1
2.5
—
—
—
0
0
147
1537
0.89
0.65
1.9
1.8
—
—
—
0
0
86
703
1.16
0.64
9.4
5.3
24.70
24.17
mmol/l
0.67
80
664
116
969
1.14
0.64
3.6
5.9
1.62
1.39
mmol/l
1.25
108
933
12
74
1.53
0.63
1.1
1.1
—
—
—
0
0
85
918
0.87
0.63
4.4
3.7
—
—
—
0
0
805
7844
0.94
0.62
3.4
3.7
13.53
15.64
mm/h
3.30
706
7026
6
98
0.58
0.62
1.0
1.1
—
—
—
0
0
397
3952
0.93
0.60
2.9
3.0
2216.59
2259.26
ng/l
0.05
317
3423
0
19
0.00
0.60
0.0
1.2
—
—
—
0
0
50
562
0.83
0.60
1.1
1.2
—
—
—
0
0
58
641
0.85
0.58
1.8
2.8
10.18
10.74
g/l
0.60
47
577
45
351
1.21
0.58
4.3
3.2
—
—
—
0
0
16
206
0.73
0.57
2.1
4.0
0.77
1.39
%
0.57
11
166
5
83
0.57
0.56
1.0
1.3
170.00
267.71
pmol/l
—
5
70
16
205
0.73
0.55
3.3
3.4
59.50
59.27
%
0.04
16
205
21
258
0.76
0.55
1.2
1.8
—
—
—
0
0
81
866
0.88
0.54
2.8
3.5
89.33
97.39
ng/l
0.27
58
723
60
654
0.86
0.52
3.6
2.8
4.72
6.03
e9/l
0.63
42
492
15
192
0.73
0.52
1.5
1.6
1.73
4.80
iu/l
—
6
64
7
103
0.64
0.48
1.3
1.3
—
—
—
0
0
312
3104
0.94
0.48
2.5
2.9
36.05
37.30
u/l
0.11
287
2906
41
456
0.84
0.47
4.2
4.0
—
—
—
0
0
44
486
0.85
0.47
1.3
1.4
—
—
—
0
0
52
565
0.86
0.45
2.2
1.9
11.36
11.48
nmol/l
0.04
46
493
60
494
1.15
0.45
2.3
1.8
1.36
3.00
ug/l
0.92
45
424
63
674
0.88
0.45
1.6
1.4
—
—
—
0
0
42
463
0.85
0.44
3.0
3.1
4.28
4.43
pmol/l
0.43
35
408
37
411
0.85
0.43
2.4
2.0
—
—
—
0
0
6
88
0.64
0.42
1.0
1.2
—
—
—
0
0
6
89
0.63
0.42
1.0
1.2
—
—
—
0
0
131
1136
1.09
0.42
2.4
3.4
—
7.41
—
0
6
0
14
0.00
0.41
0.0
1.3
—
41.18
—
0
9
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
0.73
—
0
5
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
20
235
0.80
0.40
1.4
2.7
—
—
—
0
0
92
786
1.11
0.40
4.0
3.4
—
—
—
0
0
24
184
1.23
0.39
2.0
3.3
—
—
—
0
0
68
712
0.90
0.37
1.6
1.4
—
—
—
0
0
47
503
0.88
0.36
2.4
2.9
—
—
—
0
0
10
127
0.74
0.36
1.1
1.0
—
—
—
0
0
57
478
1.13
0.35
1.2
1.2
—
—
—
0
0
9
115
0.74
0.35
1.1
1.1
—
—
—
0
0
10
126
0.75
0.34
2.8
2.5
—
—
—
0
0
60
627
0.90
0.32
1.5
1.4
—
—
—
0
0
119
1203
0.93
0.32
2.5
2.7
236.77
335.74
ng/l
1.67
99
1081
6
44
1.29
0.32
1.0
1.1
—
—
—
0
0
11
135
0.77
0.32
1.9
1.4
—
—
—
0
0
29
233
1.17
0.32
2.1
4.1
—
—
—
0
0
228
2252
0.95
0.31
3.4
3.6
289.97
622.73
ng/l
1.27
182
1951
10
70
1.35
0.31
1.1
1.2
—
—
—
0
0
7
92
0.72
0.31
1.0
1.8
—
—
—
0
0
422
4102
0.96
0.30
2.5
2.6
131.18
165.11
ug/l
2.54
353
3677
25
276
0.85
0.30
1.6
1.6
—
—
—
0
0
643
5918
1.03
0.28
2.9
2.6
45.85
55.11
u/l
2.27
570
5289
94
952
0.93
0.28
2.3
3.5
1.23
1.23
mmol/l
0.18
76
817
10
121
0.78
0.27
1.1
1.1
—
—
—
0
0
93
939
0.93
0.26
1.9
2.2
82.49
36.42
u/l
0.38
76
800
606
5836
0.97
0.26
3.7
6.0
12.49
12.78
umol/l
0.18
543
5504
5
68
0.69
0.26
1.4
1.7
—
—
—
0
0
150
1489
0.94
0.26
2.0
2.3
1.66
1.72
%
0.24
117
1307
116
1159
0.94
0.25
6.2
6.1
94.37
95.14
%
0.47
110
1106
9
72
1.18
0.24
2.0
1.7
72.89
90.36
umol/l
—
9
72
183
1648
1.05
0.24
1.2
1.2
2.49
2.14
u/ml
0.08
54
404
5
35
1.35
0.23
2.2
2.0
—
—
—
0
0
985
9152
1.03
0.23
20.9
18.8
330.65
330.69
g/l
0.04
928
9022
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
8.6
—
—
—
0
0
5
40
1.18
0.21
1.0
1.0
—
—
—
0
0
13
147
0.83
0.21
1.9
2.7
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
0.37
—
0
5
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.20
0.0
1.0
—
—
—
0
0
6
47
1.20
0.19
1.0
1.1
—
—
—
0
0
917
8745
0.98
0.19
4.8
7.0
80.38
85.04
u/l
1.74
817
8072
6
48
1.18
0.19
1.2
1.1
—
—
—
0
0
96
954
0.95
0.19
3.8
7.0
—
—
—
0
0
366
3531
0.97
0.19
3.2
3.1
87.70
174.37
e6/l
1.14
290
2696
132
1299
0.95
0.19
1.3
1.2
—
—
—
0
0
7
55
1.20
0.18
1.4
2.1
—
—
—
0
0
26
273
0.90
0.18
3.0
2.7
—
—
—
0
0
20
213
0.88
0.17
2.2
2.5
16.39
15.15
%
—
8
89
7
59
1.12
0.17
1.4
1.9
1.04
4.65
ug/l
—
7
53
79
704
1.06
0.17
2.5
2.8
126.92
124.63
g/l
0.51
79
681
16
173
0.87
0.16
1.7
1.4
—
—
—
0
0
6
74
0.76
0.15
1.0
1.1
—
—
—
0
0
253
2442
0.97
0.14
3.0
2.9
569.01
540.26
mosm/kgh2o
1.29
206
2055
7
81
0.81
0.14
1.0
1.1
—
—
—
0
0
7
81
0.81
0.14
1.0
1.1
—
—
—
0
0
435
4027
1.02
0.14
3.8
3.5
372.67
189.68
e6/l
0.59
312
2880
11
121
0.86
0.14
1.1
1.2
—
—
—
0
0
15
125
1.13
0.12
1.1
1.3
233.00
153.48
miu/ml
—
5
50
31
312
0.93
0.10
10.4
9.7
—
—
—
0
0
6
51
1.11
0.09
1.3
1.3
—
—
—
0
0
92
892
0.97
0.08
2.0
2.1
106.07
161.81
ug/g
1.51
66
700
5
59
0.80
0.08
6.8
2.0
1.29
0.96
e9/l
—
5
52
43
387
1.05
0.08
2.0
3.0
0.18
0.34
g/l
—
8
161
6
69
0.82
0.07
2.5
1.8
—
—
—
0
0
15
129
1.10
0.07
4.4
3.1
—
—
—
0
0
9
81
1.05
0.07
1.4
1.2
—
—
nmol/l
—
0
0
8
86
0.88
0.06
3.1
2.3
—
—
—
0
0
110
1058
0.98
0.06
1.2
1.4
—
—
—
0
0
80
735
1.03
0.06
6.2
3.6
—
—
—
0
0
38
372
0.96
0.05
3.2
3.1
0.82
0.81
nmol/l
0.08
25
274
54
524
0.97
0.05
2.4
3.8
24.47
24.15
mmol/l
0.26
48
508
303
2832
1.01
0.04
3.9
3.5
—
—
—
0
0
1035
9775
0.99
0.04
4.3
4.1
1.94
2.26
mu/l
1.36
892
8538
1267
11959
0.99
0.04
19.1
16.8
3.99
4.00
mmol/l
0.48
1174
11512
138
1315
0.99
0.03
5.9
5.8
1.24
1.02
mmol/l
0.29
106
993
28
255
1.03
0.02
2.8
4.5
2.74
2.87
mmol/l
0.11
22
181
138
1312
0.99
0.02
5.8
5.8
4.98
5.07
kpa
0.43
124
1226
12
106
1.07
0.02
1.1
1.2
—
—
—
0
0
138
1311
0.99
0.02
5.8
5.8
11.78
11.87
kpa
0.05
124
1224
28
256
1.03
0.02
2.8
4.5
5.22
5.00
kpa
0.45
28
250
13
129
0.95
0.01
1.8
5.1
—
—
—
0
0
1267
11921
1.00
0.01
19.2
16.6
140.01
139.57
mmol/l
5.36
1179
11495
12
107
1.06
0.01
2.1
1.9
732.14
662.24
ml
—
7
55
31
286
1.02
0.00
2.0
2.1
19.03
94.57
ug/min
2.54
14
154
21
198
1.00
0.00
1.9
2.4
—
—
—
0
0
34
322
0.99
0.00
3.0
3.1
8.83
7.95
mmol/l
0.62
34
313
18
172
0.99
0.00
1.3
1.3
80.92
62.65
mmol/l
0.82
13
135
0
5
0.00
-0.00
0.0
1.2
—
374.80
—
0
5
0
7
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
63
0.90
-0.00
3.3
7.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
6.2
—
0.15
—
0
5
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
6
61
0.93
-0.00
1.2
1.2
1.03
1.63
nmol/l
—
6
56
0
9
0.00
-0.00
0.0
2.3
—
—
—
0
0
9
89
0.95
-0.00
1.8
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
1.55
—
0
5
0
5
0.00
-0.00
0.0
1.4
—
389.80
—
0
5
0
8
0.00
-0.00
0.0
2.8
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: AD_EO_EXMORE – Alzheimer’s disease (Early onset), excluding more controls

GWS hits: 5

This endpoint is excluded (different definition than used in FinnGen).