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Alzheimer’s disease (Early onset)

AD_EO

Alzheimer's disease: A progressive, neurodegenerative disease characterized by loss of function and death of nerve cells in several areas of the brain leading to loss of cognitive function such as memory and language.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

2035

4. Check minimum number of events

None

2035

5. Include endpoints

None

2035

6. Filter based on genotype QC (FinnGen only)

1965

Control definitions (FinnGen only)

Control exclude
G6_ALZHEIMER

Extra metadata

First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 1965 967 998
Unadjusted period prevalence (%) 0.40 0.34 0.46
Median age at first event (years) 75.62 73.65 77.54

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2035
Matched controls
20349
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
N06DA02
ATC
donepezil; oral
62.6
307.7
1094
371
N06DX01
ATC
memantine; oral
64.3
307.7
1244
486
F00.10*G30.1
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset without additional symptoms
77.0
307.7
536
94
G30
ICD-10 Finland
Alzheimer disease
95.2
307.7
236
28
F00.00*G30.0
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset without additional symptoms
2250.9
307.7
726
5
G30.8
ICD-10 Finland
Other Alzheimer disease
56.0
307.7
238
48
N06DA04
ATC
galantamine; oral
24.2
307.7
305
147
G30.0
ICD-10 Finland
Alzheimer disease with early onset
16384.0
307.7
1154
*
G30.1
ICD-10 Finland
Alzheimer disease with late onset
90.4
307.7
952
196
N05AX08
ATC
risperidone; systemic
11.1
307.7
694
910
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
7.8
307.7
627
1094
N06DA03
ATC
rivastigmine; oral, transdermal
36.1
307.7
687
283
G30.9
ICD-10 Finland
Alzheimer disease, unspecified
472.9
307.7
820
29
307
Kela drug reimbursment
Tacrine, donepezil, rivastigmine, galantamine and other major and expensive drugs used to treat Alzheimer's disease
145.1
307.7
1131
174
F00.10
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset without additional symptoms
81.9
307.7
226
31
F0009, G300,
ICD-10 Finland
+∞
296.3
277
*
P70
ICPC
Dementia
14.7
293.3
276
215
P20
ICPC
Memory disturbance
5.4
275.2
743
1956
F03
ICD-10 Finland
Unspecified dementia
6.9
258.2
461
823
TAB00
NOMESCO Finland
Lumbar puncture
13.2
252.9
253
217
N05AH04
ATC
quetiapine; oral
5.3
229.9
590
1465
F00.00
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset without additional symptoms
740.7
207.3
201
*
F00.20*G30.8
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type without additional symptoms
18.9
207.1
167
96
F0019, G301,
ICD-10 Finland
+∞
199.3
188
*
F00.9
ICD-10 Finland
Dementia in Alzheimer disease, unspecified
91.3
198.3
104
12
XA800
NOMESCO Finland
Neuropsychological investigation
12.6
195.6
199
174
F009, G309,
ICD-10 Finland
+∞
139.2
132
*
F06.7
ICD-10 Finland
Mild cognitive disorder
7.0
119.9
193
301
SPAT1053
SPAT
Memory test
3.2
108.2
552
2116
N03AG01
ATC
valproic acid; systemic, rectal
5.5
100.7
208
413
Z75.5
ICD-10 Finland
Holiday relief care
8.1
83.0
114
148
F00.20
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type without additional symptoms
26.9
79.9
55
21
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
4.4
79.6
213
523
SPAT1245
SPAT
Provision of support and information to patient’s family members
4.1
77.8
237
641
R41.3
ICD-10 Finland
Other amnesia
5.9
77.4
145
262
F05.1
ICD-10 Finland
Delirium superimposed on dementia
13.2
77.1
74
58
N05BA04
ATC
oxazepam; oral
2.4
68.8
673
3483
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
3.6
63.5
226
678
N05AD01
ATC
haloperidol; systemic
4.3
60.4
165
410
N05AH03
ATC
olanzapine; systemic
4.6
57.7
142
325
F00.09
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset information on additional symptoms is lacking
+∞
53.4
51
*
WYA20
NOMESCO Finland
Home visit
5.3
47.6
99
196
R53
ICD-10 Finland
Malaise and fatigue
2.1
44.4
600
3431
Z2445
NOMESCO Finland
Psychologist
5.9
44.4
81
142
N05BA06
ATC
lorazepam; systemic, sublingual
3.2
43.6
188
633
N06AB10
ATC
escitalopram; oral
2.4
43.3
353
1647
SPAT1234
SPAT
Support of social functional capacity
2.9
42.1
213
785
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.9
39.5
799
5202
A28
ICPC
Limited function/disability NOS
2.0
38.2
548
3176
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
2.5
37.8
272
1195
N06AX11
ATC
mirtazapine; oral
1.9
37.7
688
4320
F00.01
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset other additional symptoms, mainly paranoidism
+∞
37.6
36
*
N06AB04
ATC
citalopram; systemic
2.0
36.9
495
2796
F0029, G308,
ICD-10 Finland
+∞
35.5
34
*
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
2.3
33.9
287
1352
SPAT1216
SPAT
Assessment of functional ability
2.0
33.2
443
2487
R41.0
ICD-10 Finland
Disorientation, unspecified
3.3
33.1
132
423
R56.8
ICD-10 Finland
Other and unspecified convulsions
3.3
32.7
127
400
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.8
30.6
161
604
F0014, G301,
ICD-10 Finland
+∞
30.3
29
*
SAB01
NOMESCO Finland
Restricted oral and dental health check by dental hygienist or dental assistant
2.9
30.2
145
517
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
5.1
30.2
64
129
N07AA05, ,
ATC
306.8
29.9
30
*
N05AD03
ATC
melperone; systemic
4.2
28.7
77
188
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.7
27.4
768
5354
A06AD11
ATC
lactulose; oral
1.8
26.3
504
3151
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
2.8
26.2
138
517
SPAT1254
SPAT
Administration of medicine
1.9
26.2
391
2262
F00
ICD-10 Finland
Dementia in Alzheimer disease
23.5
26.1
37
16
F0004, G300,
ICD-10 Finland
+∞
26.1
25
*
F00.04
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset other additional symptoms of mixed type
+∞
26.1
25
*
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.9
25.8
392
2280
Z02.4
ICD-10 Finland
Examination for driving licence
0.4
25.4
145
3248
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.4
25.0
175
755
F00.0
ICD-10 Finland
Dementia in Alzheimer disease with early onset
253.2
24.7
25
*
F001, G301,
ICD-10 Finland
253.2
24.7
25
*
F00.1
ICD-10 Finland
Dementia in Alzheimer disease with late onset
91.2
24.7
27
*
G91.2
ICD-10 Finland
Normal-pressure hydrocephalus
4.2
23.7
63
153
N02AJ06
ATC
codeine and paracetamol; systemic
0.5
23.2
247
4413
F00.14
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset other additional symptoms of mixed type
65.7
22.9
26
*
F00.19
ICD-10 Finland
Dementia in Alzheimer's disease with late onset without information about additional symptoms
84.4
22.7
25
*
G40.9
ICD-10 Finland
Epilepsy, unspecified
3.1
22.3
93
306
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.8
21.7
418
2601
G31.0
ICD-10 Finland
Circumscribed brain atrophy
7.2
21.6
32
45
AA5DR
NOMESCO Finland
Brain metabolism PET with CT
212.1
20.6
21
*
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
2.5
20.6
132
546
H04AA01
ATC
glucagon; nasal, parenteral
6.4
20.6
34
54
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.2
20.2
181
867
S18
ICPC
Laceration/cut
0.6
20.0
386
5844
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.8
19.9
385
2391
F000, G300,
ICD-10 Finland
+∞
18.8
18
*
N02AA05
ATC
oxycodone; systemic
1.7
18.2
439
2890
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.7
17.9
396
2547
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.6
17.8
496
3380
N06AX26
ATC
vortioxetine; oral
2.7
17.8
97
370
F00.02
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset other additional symptoms, mainly illusions
181.5
17.5
18
*
G31.8
ICD-10 Finland
Other specified degenerative diseases of nervous system
7.4
17.4
25
34
Z13.3
ICD-10 Finland
Special screening examination for mental and behavioural disorders
171.3
16.5
17
*
S72.0
ICD-10 Finland
Fracture of neck of femur
2.1
16.3
169
855
E86
ICD-10 Finland
Volume depletion
2.7
16.2
90
347
130
Kela drug reimbursment
Malignant tumour
0.2
16.2
30
1210
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
0.5
16.0
166
3043
F0009, G309,
ICD-10 Finland
+∞
15.6
15
*
F0001, G300,
ICD-10 Finland
+∞
15.6
15
*
SPAT1251
SPAT
Organisation of medication
2.3
15.4
121
548
R55
ICD-10 Finland
Syncope and collapse
1.7
14.4
274
1683
R23.8
ICD-10 Finland
Other and unspecified skin changes
0.4
14.3
99
2095
LAITO, ,
NOMESCO Finland
13.5
14.2
24
18
SPAT1153
SPAT
Removal of sutures
0.6
14.0
249
3922
A10AB05
ATC
insulin aspart; parenteral
2.0
13.7
156
817
3310A
ICD-9 Finland
Other cerebral degenerations, Alzheimer's disease
+∞
13.6
13
*
R99
ICD-10 Finland
Other ill-defined and unspecified causes of mortality
2.7
13.4
71
268
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
2.7
13.3
73
280
R1250
NOMESCO Finland
Evaluation of functional capability
3.5
13.3
46
135
N06AB06
ATC
sertraline; oral
2.0
13.0
152
802
GD1AA
NOMESCO Finland
Thorax X-ray examination
0.7
12.9
529
6948
F00.11
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset other additional symptoms, mainly paranoidism
50.3
12.8
15
*
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
0.5
12.7
153
2693
-, ,
ICD-10 Finland
2.7
12.4
65
244
L82
ICD-10 Finland
Seborrhoeic keratosis
0.5
12.4
102
2033
SPAT1229
SPAT
Assessment of need for aid
1.8
12.2
193
1125
SPAT1172
SPAT
Guidance concerning hydration
2.4
12.1
80
337
NFB20
NOMESCO Finland
Primary partial prosthetic replacement of hip joint using cement, other or unspecified
2.1
11.8
106
509
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
0.6
11.6
173
2869
E87.0
ICD-10 Finland
Hyperosmolality and hypernatraemia
5.7
11.5
21
37
M79.6
ICD-10 Finland
Pain in limb
0.7
11.5
354
4945
N07AA06, ,
ATC
+∞
11.5
11
*
F22.0
ICD-10 Finland
Delusional disorder
3.6
11.5
37
104
A03FA01
ATC
metoclopramide; systemic, rectal
0.6
11.4
181
2957
G40.2
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
4.5
11.4
27
60
L17
ICPC
Foot/toe symptom/complaint
0.6
11.4
204
3228
WX402
NOMESCO Finland
General anaesthesia
0.5
11.2
80
1681
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.6
11.1
263
1707
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
0.5
10.9
139
2417
N05AH02
ATC
clozapine; systemic
5.4
10.9
21
39
J01CA08
ATC
pivmecillinam; oral
1.4
10.7
738
5925
Z29
ICPC
Social problem NOS
3.0
10.6
47
161
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
3.0
10.6
46
156
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
0.5
10.6
100
1907
K86
ICPC
Hypertension uncomplicated
0.5
10.5
77
1603
F0001, G301,
ICD-10 Finland
+∞
10.4
10
*
Z28
ICPC
Limited function/disability (Z)
5.2
10.3
21
41
207
Kela drug reimbursment
Chronic arrhythmias
0.6
10.2
185
2927
SPAT1360
SPAT
Extensive global examination
1.9
10.2
131
715
N04BA02
ATC
levodopa and decarboxylase inhibitor; oral
2.0
10.0
102
513
H02AB02
ATC
dexamethasone; systemic
0.4
10.0
45
1142
F05.9
ICD-10 Finland
Delirium, unspecified
2.3
10.0
71
309
M01AH05
ATC
etoricoxib; oral
0.7
10.0
553
6978
G31.1
ICD-10 Finland
Senile degeneration of brain, not elsewhere classified
16.8
9.9
15
9
R41
ICD-10 Finland
Other symptoms and signs involving cognitive functions and awareness
4.3
9.8
25
59
S70.0
ICD-10 Finland
Contusion of hip
2.0
9.8
105
539
L57.0
ICD-10 Finland
Actinic keratosis
0.5
9.7
90
1730
L28
ICPC
Limited function/disability (L)
1.5
9.6
405
2971
JN4AD
NOMESCO Finland
Body CT examination
0.4
9.6
40
1049
G31.9
ICD-10 Finland
Degenerative disease of nervous system, unspecified
8.4
9.6
20
24
SPAT1252
SPAT
Overall medication plan or its review
1.8
9.4
156
920
F0011, G301,
ICD-10 Finland
100.5
9.4
10
*
B01AF02
ATC
apixaban; oral
0.5
9.4
108
1938
C04AE01
ATC
ergoloid mesylates; systemic
3.2
9.3
35
109
N02BE01
ATC
paracetamol; systemic, rectal
1.4
9.2
1557
14231
SPAT1301
SPAT
No procedures
1.4
9.2
540
4200
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
3.3
9.2
34
105
B03BA03
ATC
hydroxocobalamin; parenteral
1.7
9.1
152
900
AA1AD
NOMESCO Finland
CT of head and brain
1.4
9.0
539
4200
F02.09*G31.0
ICD-10 Finland
Dementia in Pick's disease without information on additional symptoms
18.7
8.9
13
7
N02AX02
ATC
tramadol; systemic, rectal
0.7
8.9
530
6642
SAD01
NOMESCO Finland
Assessment of need for oral health care, standard
1.7
8.8
161
976
R05
ICPC
Cough
0.6
8.8
147
2380
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
0.7
8.8
252
3601
C08CA01
ATC
amlodipine; oral
0.7
8.8
526
6591
C03DA01
ATC
spironolactone; oral
0.6
8.7
136
2240
L08
ICPC
Shoulder symptom/complaint
0.6
8.7
135
2226
R06.0
ICD-10 Finland
Dyspnoea
0.7
8.6
301
4140
WZC30
NOMESCO Finland
Teaching
0.5
8.6
77
1494
S06.0
ICD-10 Finland
Concussion
1.6
8.6
186
1181
R4110
NOMESCO Finland
Physiotherapy
0.7
8.6
247
3528
E000001, ,
ATC
1.5
8.5
328
2363
S72.1
ICD-10 Finland
Pertrochanteric fracture
2.0
8.5
89
454
K85
ICPC
Elevated blood pressure
0.6
8.5
127
2114
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.5
8.4
252
1724
F0003, G300,
ICD-10 Finland
+∞
8.3
8
*
F00.03
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenil onset other additional symptoms, mainly depression
+∞
8.3
8
*
F0002, G300,
ICD-10 Finland
+∞
8.3
8
*
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.5
8.2
239
1623
W19
ICD-10 Finland
Unspecified fall
1.6
8.2
195
1264
T36
ICD-10 Finland
Poisoning by systemic antibiotics
2.4
8.2
53
222
NFJ54
NOMESCO Finland
Internal fixation of fracture of upper femur with intramedullary nail
2.3
8.2
62
279
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.0
8.1
84
427
H02AB06
ATC
prednisolone; systemic
0.7
8.0
590
7195
R03AC02
ATC
salbutamol; inhalant
0.7
7.9
595
7244
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
2.8
7.9
38
137
N30.9
ICD-10 Finland
Cystitis, unspecified
1.7
7.9
141
850
A10BK03
ATC
empagliflozin; oral
0.4
7.8
34
872
L03
ICPC
Low back symptom/complaint
0.6
7.7
184
2739
SPAT1246
SPAT
Screening of depression or other psychiatric problem
2.6
7.6
42
163
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.5
7.6
290
2083
4340A
ICD-9 Finland
Occlusion of cerebral arteries, Cerebral thrombosis
0.1
7.6
*
250
F009, F03,
ICD-10 Finland
25.1
7.6
10
*
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
0.5
7.6
52
1108
SPAT1304
SPAT
Counselling and guidance related to ageing
1.6
7.5
183
1194
SPAT1279
SPAT
Preparation of immediate hospitalisation
2.6
7.5
42
164
N05CD07
ATC
temazepam; oral
1.4
7.5
328
2415
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
2.4
7.5
51
219
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
0.7
7.4
198
2881
M17
ICD-10 Finland
Gonarthrosis [arthrosis of knee]
0.5
7.4
68
1309
F29
ICD-10 Finland
Unspecified nonorganic psychosis
2.7
7.4
37
137
Q90.9
ICD-10 Finland
Down syndrome, unspecified
+∞
7.3
7
*
F0009, G301,
ICD-10 Finland
+∞
7.3
7
*
L89
ICD-10 Finland
Decubitus ulcer and pressure area
2.3
7.2
54
242
XX3DW
NOMESCO Finland
Time consuming IT work
0.5
7.1
52
1081
A10AE04
ATC
insulin glargine; parenteral
1.6
7.1
173
1131
J01EA01
ATC
trimethoprim; systemic
1.3
7.1
546
4404
H81
ICPC
Excessive ear wax
0.6
7.0
157
2371
SPAT1101
SPAT
Orthostatic test
1.8
7.0
110
642
C09CA06
ATC
candesartan; oral
0.7
6.9
195
2810
L15
ICPC
Knee symptom/complaint
0.6
6.9
167
2483
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
0.4
6.8
37
862
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
1.6
6.8
169
1110
F00.13
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset other additional symptoms, mainly depression
40.2
6.8
8
*
N30.0
ICD-10 Finland
Acute cystitis
1.4
6.8
291
2136
WW200, ,
SPAT
0.6
6.7
141
2166
M54.5
ICD-10 Finland
Low back pain
0.7
6.7
296
3931
N03AX14
ATC
levetiracetam; systemic
2.3
6.7
46
199
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
0.2
6.6
7
327
F06.9
ICD-10 Finland
Unspecified mental disorder due to brain damage and dysfunction and to physical disease
8.7
6.5
13
15
P28
ICPC
Limited function/disability (P)
5.3
6.5
18
34
S06.2
ICD-10 Finland
Diffuse brain injury
3.5
6.4
21
60
N28
ICPC
Limited function/disability (N)
2.7
6.4
33
124
N39.9
ICD-10 Finland
Disorder of urinary system, unspecified
2.3
6.4
47
210
U04
ICPC
Incontinence urine
1.7
6.3
112
675
EBA15
NOMESCO Finland
Extraction of multiple teeth
2.0
6.3
65
331
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
3.9
6.3
18
47
A04
ICPC
Weakness/tiredness general
1.4
6.3
264
1930
F0023, G308,
ICD-10 Finland
+∞
6.3
6
*
F0024, G308,
ICD-10 Finland
+∞
6.3
6
*
F009, G300,
ICD-10 Finland
+∞
6.3
6
*
F0019, G300,
ICD-10 Finland
+∞
6.3
6
*
F0010, G300,
ICD-10 Finland
+∞
6.3
6
*
DFF00
NOMESCO Finland
Pure tone audiometry
0.5
6.2
61
1146
R74
ICPC
Upper respiratory infection acute
0.6
6.2
136
2064
A02BC02
ATC
pantoprazole; systemic
0.8
6.2
927
10448
S21
ICPC
Skin texture symptom/complaint
0.6
6.1
84
1434
WF049
NOMESCO Finland
Radiotherapy of metastasis
0.2
6.1
8
330
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
4.1
6.1
16
39
R4110, ,
SPAT
0.4
6.1
34
781
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
3.2
6.0
23
73

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
238
39
68.97
307.65
1.0
1.0
411.35
229.79
ng/l
7.43
189
19
243
39
70.62
307.65
1.0
1.0
532.54
796.00
ng/l
2.23
189
20
239
225
11.90
224.45
1.1
1.2
433.26
570.41
mg/l
3.36
228
216
227
198
12.78
224.00
1.1
1.2
3.75
3.87
mmol/l
0.64
216
185
224
196
12.72
220.54
1.2
1.3
124.42
1070.46
e6/l
0.87
179
164
224
196
12.72
220.54
1.1
1.2
2.26
36.24
e6/l
1.36
171
158
180
173
11.32
165.86
1.1
1.2
—
—
—
0
0
104
86
12.69
105.13
1.2
1.2
—
—
—
0
0
74
88
8.69
57.74
1.1
1.2
—
—
—
0
0
86
149
5.98
47.74
3.4
4.4
322.13
346.31
umol/l
0.67
70
124
861
11731
0.54
39.50
3.9
4.5
1.50
1.46
mmol/l
2.23
751
10452
877
11866
0.54
39.02
3.9
4.6
4.56
4.48
mmol/l
1.20
773
10688
917
12242
0.54
38.89
4.3
5.1
2.66
2.59
mmol/l
1.42
799
10940
830
11377
0.54
38.14
3.5
4.1
1.20
1.28
mmol/l
3.40
713
10061
39
35
11.34
37.17
1.1
1.1
—
71.60
%
—
0
5
556
3444
1.85
30.60
1.8
1.8
1201.79
1172.24
nmol/l
0.33
399
2561
938
11779
0.62
23.77
5.8
6.4
42.40
41.26
mmol/mol
1.92
798
10601
986
12204
0.63
23.03
4.2
4.9
6.20
6.10
mmol/l
0.77
846
10757
301
5033
0.53
22.86
1.9
2.3
—
—
—
0
0
422
6181
0.60
18.90
2.3
2.7
—
—
—
0
0
246
4132
0.54
18.18
2.8
3.1
50.27
214.34
mg/l
2.81
153
2622
270
4410
0.55
18.10
3.3
3.6
7.02
10.96
mg/mmol
0.85
165
2747
422
6115
0.61
17.80
5.1
5.4
59.94
59.08
%
0.68
375
5631
256
4184
0.56
17.02
2.6
3.0
7.14
6.79
mmol/l
0.69
192
3393
428
6093
0.62
16.38
4.9
5.4
2.80
2.82
%
0.06
378
5593
441
6234
0.63
16.36
5.0
5.6
25.37
25.55
%
0.12
390
5734
470
6533
0.64
16.10
5.2
5.3
1.71
1.85
e9/l
1.62
389
5644
432
6118
0.63
16.09
5.4
5.7
8.62
8.90
%
0.80
385
5621
413
5904
0.62
16.01
4.6
5.4
0.63
0.63
%
0.05
363
5413
415
5922
0.62
15.94
4.5
5.7
—
—
—
0
0
380
5527
0.62
15.82
8.5
10.1
0.00
0.00
e9/l
0.13
294
4460
479
6604
0.64
15.69
5.2
5.3
0.18
0.20
e9/l
0.98
391
5657
69
1759
0.37
15.65
1.2
1.2
6.02
14.32
u/ml
1.40
24
611
458
6371
0.64
15.61
5.1
5.1
0.58
0.62
e9/l
2.46
377
5381
463
6397
0.64
15.18
5.1
5.1
0.04
0.04
e9/l
1.41
380
5408
733
9207
0.68
14.78
3.8
4.2
—
—
—
0
0
568
7472
0.67
14.46
7.0
7.9
4.47
4.33
e9/l
0.57
474
6430
176
3064
0.53
14.21
1.5
1.6
1.28
1.34
mmol/l
0.42
150
2532
237
3713
0.59
12.92
2.1
2.7
2839.59
8311.61
umol/l
2.14
193
3125
1155
13230
0.71
12.83
7.9
10.7
22.94
24.30
u/l
1.05
1055
12605
88
1829
0.46
11.99
1.2
1.2
19.88
37.75
iu/ml
1.94
26
593
225
3508
0.60
11.91
3.0
3.2
—
—
—
0
0
876
10438
0.72
11.82
19.0
20.9
15.22
15.51
%
0.75
831
10151
400
5452
0.67
11.46
3.0
3.3
2217.34
2316.02
ng/l
0.13
319
4708
316
4506
0.65
11.26
2.1
2.5
—
—
—
0
0
26
57
4.61
11.19
1.0
1.1
37.94
42.25
mg/l
0.20
19
48
291
4203
0.64
10.96
3.2
3.4
0.58
0.56
e6/l
0.06
234
3287
222
3389
0.61
10.64
2.1
2.4
—
—
—
0
0
22
44
5.04
10.52
1.5
1.5
—
—
—
0
0
47
1171
0.39
10.04
1.3
1.4
—
—
—
0
0
810
9625
0.74
9.92
3.4
4.1
13.56
15.68
mm/h
3.42
708
8751
65
1398
0.45
9.67
1.2
1.3
515.56
540.32
titre
—
9
309
21
27
7.85
9.61
1.2
1.2
—
17.00
%
—
0
5
87
1680
0.50
9.54
1.3
1.4
—
—
—
0
0
130
2213
0.56
9.43
2.1
2.5
21.55
20.69
%
0.27
90
1867
120
2061
0.56
8.97
4.0
4.8
1.04
1.05
mmol/l
0.14
103
1866
150
2421
0.59
8.89
3.0
3.1
3.80
2.51
e6/l
0.66
83
1374
144
2343
0.59
8.80
1.9
2.4
2.19
2.27
g/l
0.91
115
2136
424
5468
0.72
8.36
2.5
2.8
130.96
145.21
ug/l
0.78
354
4872
164
2545
0.61
8.26
2.7
2.9
1.71
1.45
e6/l
0.34
96
1487
197
2927
0.64
8.19
1.2
1.3
—
—
—
0
0
293
4015
0.68
8.15
3.2
3.4
—
—
—
0
0
42
1003
0.41
8.14
1.4
1.5
—
—
—
0
0
165
2531
0.62
7.89
1.9
2.4
11.82
11.60
umol/l
0.13
132
2319
436
3356
1.38
7.73
1.7
1.7
445.55
10067295.23
pmol/l
1.57
358
2692
608
7350
0.75
7.63
3.7
5.6
12.49
12.57
umol/l
0.04
544
6919
93
1638
0.55
7.57
2.2
3.6
16.13
21.12
ug/l
0.18
76
1367
153
2340
0.63
7.19
2.2
2.9
0.83
0.81
mmol/l
1.29
136
2126
342
4476
0.72
7.18
4.0
4.4
—
—
—
0
0
921
10474
0.78
6.99
4.8
7.1
80.33
82.78
u/l
0.70
818
9706
79
1418
0.54
6.86
4.2
5.9
12.53
12.11
mmol/l
0.14
69
1317
203
2870
0.67
6.53
1.5
1.7
1.78
1.42
mg/l
0.27
138
2226
127
1967
0.62
6.29
1.5
1.4
2.63
2.63
g/l
0.01
67
1127
380
2950
1.35
6.28
5.4
4.7
1.02
1.02
kg/l
0.70
57
493
81
1403
0.56
6.22
1.8
2.3
65.42
65.67
g/l
0.11
67
1234
60
1125
0.52
6.03
2.5
3.9
2.24
0.94
%
0.45
19
433
52
1006
0.50
5.77
2.3
3.8
0.86
0.64
%
0.13
14
371
368
4623
0.75
5.72
3.2
3.5
87.36
82.77
e6/l
0.06
292
3622
188
2617
0.69
5.52
2.7
3.3
0.98
0.85
ug/l
0.33
129
1823
264
3461
0.73
5.43
3.1
3.8
85.82
83.55
%
0.66
251
3349
58
1060
0.53
5.38
2.6
3.9
0.12
0.11
%
0.01
17
371
228
3051
0.72
5.33
3.4
4.5
289.97
307.47
ng/l
0.05
182
2667
52
978
0.52
5.30
2.6
4.0
0.08
0.44
%
0.62
12
299
1042
11493
0.81
5.27
4.3
4.7
1.94
2.15
mu/l
0.92
897
10191
647
7495
0.80
5.13
2.9
3.1
45.76
55.46
u/l
2.56
572
6788
52
266
1.98
5.04
1.1
1.3
—
—
—
0
0
78
1286
0.59
5.01
1.7
1.9
0.19
0.20
g/l
0.24
67
1182
365
2907
1.31
4.99
2.4
3.0
2.44
2.47
mmol/l
6.34
289
2490
31
681
0.45
4.97
1.9
1.7
1.96
1.54
g/l
0.30
24
609
579
4901
1.25
4.85
2.1
3.2
2.35
2.35
mmol/l
0.24
474
4169
70
1175
0.58
4.83
1.8
2.1
—
—
—
0
0
22
545
0.40
4.76
1.1
1.4
—
8.73
—
0
6
255
3294
0.74
4.72
3.0
3.1
568.65
530.17
mosm/kgh2o
2.12
208
2819
1189
12872
0.82
4.72
16.3
17.3
—
—
—
0
0
174
1249
1.43
4.58
3.7
3.6
—
—
—
0
0
17
54
3.17
4.48
1.1
1.1
127.65
132.41
nmol/l
0.23
17
54
60
1028
0.57
4.48
1.4
1.5
—
—
—
0
0
101
1525
0.64
4.48
2.0
2.5
10.83
10.25
umol/l
0.08
78
1314
99
1494
0.65
4.38
1.9
2.4
62.62
68.47
e9/l
1.15
80
1161
8
273
0.29
4.24
1.9
1.4
—
—
—
0
0
438
5207
0.80
4.20
3.8
4.0
370.59
127.98
e6/l
0.90
314
3861
85
1311
0.63
4.16
1.2
1.3
—
—
—
0
0
312
3847
0.78
4.06
2.5
3.0
36.05
34.81
u/l
0.16
287
3627
48
849
0.55
4.05
1.3
1.6
1.58
1.55
g/l
0.08
30
715
150
2056
0.71
4.02
1.9
1.9
—
—
—
0
0
1283
13701
0.83
4.00
23.1
25.9
242.49
241.58
e9/l
0.19
1185
13206
1284
13704
0.83
3.95
23.1
26.1
129.62
130.52
g/l
1.28
1199
13368
1284
13702
0.83
3.93
23.0
25.9
4.30
4.33
e12/l
1.53
1176
13146
1284
13701
0.83
3.92
22.9
25.8
91.48
91.74
fl
1.21
1203
13347
1284
13700
0.83
3.91
22.9
25.8
30.30
30.36
pg
0.50
1202
13346
47
825
0.56
3.87
3.2
6.3
24.87
24.94
mmol/l
0.05
47
816
1284
13694
0.83
3.86
23.0
25.9
38.05
38.54
%
1.30
1120
12559
1285
13702
0.83
3.85
23.1
25.9
7.06
6.97
e9/l
0.61
1177
13145
31
615
0.50
3.81
1.3
2.1
10.72
10.46
g/l
0.16
25
530
49
273
1.81
3.76
1.7
2.7
31.24
33.71
umol/l
0.20
42
235
150
2032
0.72
3.76
2.0
2.3
1.66
1.81
%
0.85
117
1765
16
403
0.39
3.67
1.7
1.4
—
—
—
0
0
708
6272
1.20
3.60
2.1
2.1
96.91
92.29
pmol/l
1.59
352
3198
265
3278
0.78
3.51
5.3
6.1
—
—
—
0
0
678
7603
0.84
3.46
16.1
20.3
1.33
1.41
inr
1.13
156
2079
381
4514
0.81
3.45
4.0
5.4
3.57
4.96
ug/l
0.66
325
3961
57
920
0.61
3.44
4.0
4.1
—
—
—
0
0
46
784
0.58
3.44
8.6
8.3
—
—
—
0
0
44
755
0.57
3.38
1.3
1.2
—
—
—
0
0
6
208
0.29
3.35
1.2
1.6
2.35
4.72
mmol/24h
—
6
176
83
1224
0.66
3.34
2.8
3.5
88.52
96.73
ng/l
0.28
59
1016
25
506
0.49
3.30
1.3
2.1
38.51
36.61
g/l
0.93
19
423
14
48
2.93
3.30
3.6
3.0
28.00
30.40
umol/l
—
6
35
116
1599
0.71
3.24
6.2
6.3
94.37
94.99
%
0.36
110
1525
6
204
0.29
3.21
1.0
1.5
—
—
—
0
0
861
9420
0.85
3.19
3.4
3.9
15.13
15.13
pmol/l
0.01
736
8316
119
1628
0.71
3.18
2.5
3.3
236.77
320.97
ng/l
1.45
99
1470
0
84
0.00
3.10
0.0
1.2
—
—
—
0
0
50
805
0.61
3.02
5.4
7.7
24.73
24.61
mmol/l
0.11
42
756
10
26
3.86
2.98
1.2
1.0
1726.90
1798.38
miu/ml
—
10
26
132
1744
0.74
2.85
1.3
1.2
—
—
—
0
0
356
4170
0.82
2.84
2.1
2.3
3.19
3.23
mg/l
0.12
274
3475
138
1802
0.75
2.76
5.9
6.0
1.24
1.34
mmol/l
0.12
106
1400
60
904
0.65
2.73
2.1
2.5
—
—
—
0
0
138
1796
0.75
2.70
5.8
6.1
11.78
11.66
kpa
0.08
124
1685
138
1795
0.75
2.69
5.8
6.1
4.98
5.08
kpa
0.53
124
1683
16
342
0.46
2.53
1.1
1.3
—
7.48
—
0
6
1275
13413
0.87
2.47
19.1
21.5
4.00
4.01
mmol/l
0.85
1181
12947
96
1295
0.73
2.41
3.8
6.5
—
—
—
0
0
50
760
0.65
2.40
1.1
1.1
—
—
—
0
0
18
360
0.50
2.38
1.5
1.4
—
—
—
0
0
13
292
0.44
2.36
1.2
1.1
—
—
—
0
0
766
8325
0.87
2.35
4.4
4.6
7.18
6.90
mmol/l
1.96
693
7838
1275
13388
0.87
2.31
19.2
21.3
140.00
139.42
mmol/l
8.73
1186
12940
9
218
0.41
2.30
1.7
1.4
—
—
—
0
0
58
846
0.68
2.29
1.8
2.7
10.18
10.71
g/l
0.61
47
758
37
592
0.62
2.25
2.4
2.1
—
—
—
0
0
406
3560
1.18
2.21
5.1
4.5
0.00
0.00
estimate
0.69
73
1147
131
1664
0.77
2.18
2.4
3.2
—
7.38
—
0
13
60
860
0.69
2.17
1.5
1.4
—
—
—
0
0
94
1247
0.74
2.14
2.3
3.7
1.23
1.22
mmol/l
0.30
76
1075
10
36
2.79
2.13
2.8
2.5
39190.00
40794.58
ug/l
—
10
36
23
410
0.56
2.13
2.3
3.1
—
—
—
0
0
110
1423
0.76
2.10
1.2
1.4
—
—
—
0
0
36
568
0.63
2.08
1.2
1.2
56.99
137.68
iu/ml
1.86
18
202
183
2222
0.81
2.08
1.2
1.2
2.49
1.75
u/ml
0.20
54
579
29
478
0.60
2.02
1.2
1.4
—
—
—
0
0
5
145
0.34
2.01
1.2
1.7
0.39
0.97
g/l
—
5
109
85
1130
0.74
1.98
4.4
4.5
—
—
—
0
0
60
843
0.70
1.97
3.6
3.2
4.72
6.15
e9/l
0.76
42
608
93
1218
0.75
1.96
1.9
2.3
82.49
39.30
u/l
0.35
76
1025
41
618
0.66
1.95
1.2
1.2
—
—
—
0
0
12
255
0.47
1.93
1.5
2.0
—
—
—
0
0
303
3482
0.85
1.93
3.9
4.1
—
—
—
0
0
13
58
2.25
1.91
1.2
1.2
—
—
—
0
0
0
50
0.00
1.88
0.0
1.5
—
—
—
0
0
80
1060
0.74
1.84
6.2
4.1
—
—
—
0
0
5
12
4.17
1.82
1.0
1.0
—
—
—
0
0
18
327
0.55
1.82
1.3
1.3
80.92
60.67
mmol/l
0.96
13
258
14
275
0.51
1.81
1.1
1.1
—
85.50
—
0
20
54
760
0.70
1.81
2.4
3.1
24.47
24.19
mmol/l
0.23
48
730
15
287
0.52
1.80
1.1
1.3
—
—
—
0
0
15
286
0.52
1.78
1.1
1.2
—
1062.00
—
0
10
5
136
0.37
1.75
1.0
1.3
170.00
287.03
pmol/l
—
5
117
15
74
2.03
1.75
1.2
1.8
19.16
31.50
umol/l
—
5
8
9
193
0.46
1.73
1.6
1.5
—
—
—
0
0
131
1613
0.80
1.72
2.5
3.2
5.80
5.83
kpa
0.12
122
1550
291
3323
0.85
1.72
2.7
2.7
6.28
5.02
e6/l
1.02
258
2983
63
855
0.73
1.71
1.6
1.5
—
—
—
0
0
10
213
0.47
1.65
1.7
1.6
—
—
—
0
0
38
560
0.67
1.65
3.2
3.2
0.82
0.85
nmol/l
0.18
25
429
43
618
0.69
1.64
3.0
3.0
4.28
4.38
pmol/l
0.28
36
525
10
41
2.45
1.64
1.2
1.2
—
—
—
0
0
5
131
0.38
1.62
3.8
1.7
314.80
291.74
mu/l
—
5
121
47
661
0.70
1.60
2.4
2.7
—
—
—
0
0
79
1023
0.76
1.58
2.5
3.0
126.92
125.55
g/l
0.28
79
998
132
1605
0.81
1.57
2.5
3.2
1.95
2.06
mmol/l
0.13
108
1296
52
373
1.40
1.55
3.6
3.8
35.62
30.24
mg/l
0.35
40
262
10
207
0.48
1.54
2.0
1.4
—
—
—
0
0
11
220
0.50
1.54
1.0
1.1
—
—
—
0
0
93
1174
0.78
1.54
1.9
2.0
106.07
150.87
ug/g
1.17
66
914
10
206
0.48
1.53
1.7
1.5
—
—
—
0
0
6
144
0.41
1.51
1.8
1.1
—
—
—
0
0
1225
12747
0.90
1.50
16.9
17.9
31.54
27.13
mg/l
2.91
972
10565
0
45
0.00
1.49
0.0
1.0
—
—
—
0
0
409
3692
1.13
1.49
1.5
1.6
20.33
20.07
nmol/l
0.13
353
3074
14
72
1.95
1.48
1.2
1.2
—
—
—
0
0
12
228
0.52
1.45
1.3
2.9
—
—
—
0
0
20
328
0.61
1.44
2.3
2.6
16.39
15.36
%
—
8
173
892
9418
0.91
1.44
4.7
4.9
—
—
—
0
0
7
151
0.46
1.43
1.6
1.3
—
—
—
0
0
140
1673
0.82
1.42
1.5
1.7
—
—
—
0
0
26
399
0.65
1.41
3.0
2.9
—
—
—
0
0
6
137
0.44
1.40
1.0
1.1
—
—
—
0
0
14
74
1.90
1.39
1.2
1.2
—
—
—
0
0
14
74
1.90
1.39
1.2
1.2
—
—
—
0
0
68
880
0.76
1.39
1.6
1.4
—
—
—
0
0
25
385
0.64
1.39
1.6
1.6
—
—
—
0
0
11
210
0.52
1.36
1.7
2.8
—
—
—
0
0
20
322
0.62
1.35
1.4
2.2
—
—
—
0
0
27
175
1.55
1.34
1.1
1.2
358.81
326.54
nmol/l
0.33
22
138
0
40
0.00
1.32
0.0
1.3
—
170.49
—
0
40
10
193
0.52
1.29
1.1
1.1
—
—
—
0
0
17
281
0.60
1.29
1.1
2.9
16.61
1363.80
u/ml
0.86
12
263
13
69
1.89
1.28
1.2
1.2
—
—
—
0
0
11
205
0.53
1.28
1.2
1.2
—
—
—
0
0
16
267
0.60
1.26
2.1
3.5
0.77
1.45
%
0.62
11
227
41
562
0.72
1.25
4.2
5.0
—
—
—
0
0
30
434
0.69
1.25
1.6
1.2
—
—
—
0
0
5
118
0.42
1.24
1.0
1.1
—
—
—
0
0
23
148
1.56
1.20
3.3
3.2
—
—
—
0
0
7
145
0.48
1.20
1.4
1.2
—
—
—
0
0
16
262
0.61
1.18
3.3
3.4
59.50
60.26
%
0.13
16
262
9
171
0.52
1.18
2.1
1.5
12.04
18.88
ug/l
—
9
164
52
679
0.76
1.17
2.2
2.2
11.36
11.65
nmol/l
0.10
46
579
0
35
0.00
1.15
0.0
1.1
—
0.74
—
0
18
13
72
1.81
1.15
1.2
1.2
—
—
—
0
0
15
247
0.60
1.14
1.5
1.7
1.73
5.08
iu/l
—
6
81
13
222
0.58
1.14
1.9
2.4
—
—
—
0
0
18
283
0.63
1.13
1.1
1.1
—
—
—
0
0
342
3118
1.12
1.08
5.0
4.1
—
—
—
0
0
16
253
0.63
1.05
1.7
1.5
—
—
—
0
0
8
148
0.54
1.03
1.3
2.0
—
—
—
0
0
7
135
0.52
0.98
1.3
1.4
—
—
—
0
0
0
29
0.00
0.97
0.0
1.9
—
—
—
0
0
0
30
0.00
0.97
0.0
1.1
—
—
—
0
0
116
1353
0.85
0.96
3.6
5.6
1.62
1.42
mmol/l
1.05
108
1297
407
4383
0.91
0.95
2.2
2.4
58.70
78.52
u/l
0.54
366
4022
31
420
0.73
0.94
10.4
12.7
—
—
—
0
0
21
303
0.69
0.92
1.9
2.4
—
—
—
0
0
15
94
1.60
0.90
1.5
1.8
—
—
—
0
0
94
1106
0.84
0.88
1.6
1.9
415.24
385.79
nmol/l
0.65
74
979
11
180
0.61
0.86
1.9
1.3
—
—
—
0
0
86
1012
0.84
0.82
9.4
6.0
24.70
24.44
mmol/l
0.27
80
962
28
206
1.36
0.81
29.3
7.2
7.91
7.49
mmol/l
0.25
20
174
21
294
0.71
0.80
1.2
1.7
—
—
—
0
0
638
6070
1.07
0.79
4.1
4.4
62.36
60.97
ng/l
0.04
461
4726
117
1339
0.87
0.79
2.4
2.7
4.18
4.39
kpa
0.63
107
1280
34
441
0.77
0.79
3.0
3.5
8.83
7.82
mmol/l
0.75
34
434
17
247
0.69
0.79
1.7
1.9
1.99
1.68
mmol/l
0.42
17
240
21
293
0.71
0.79
1.3
1.2
—
—
—
0
0
406
4334
0.92
0.78
2.5
3.8
7.41
7.40
ph
1.10
63
833
5
97
0.51
0.78
1.4
1.4
—
—
—
0
0
23
165
1.40
0.77
2.0
2.0
—
—
—
0
0
0
27
0.00
0.77
0.0
1.1
—
—
—
0
0
0
27
0.00
0.77
0.0
1.1
—
—
—
0
0
0
27
0.00
0.77
0.0
1.1
—
—
—
0
0
668
6375
1.07
0.76
3.4
4.3
34.89
34.19
g/l
2.20
577
5804
6
107
0.56
0.72
1.0
1.2
—
—
—
0
0
10
159
0.63
0.72
2.8
2.6
—
—
—
0
0
6
110
0.54
0.72
2.5
1.5
—
—
—
0
0
24
321
0.74
0.71
2.0
2.8
—
—
—
0
0
44
541
0.81
0.69
1.3
1.3
—
—
—
0
0
7
42
1.67
0.68
2.0
1.7
—
—
—
0
0
92
1056
0.87
0.68
2.4
3.6
5.16
5.20
kpa
0.22
80
983
7
120
0.58
0.67
1.3
1.3
—
—
—
0
0
10
156
0.64
0.67
1.1
1.3
—
—
—
0
0
58
689
0.84
0.65
1.2
1.3
—
—
—
0
0
13
188
0.69
0.62
1.8
1.8
—
—
—
0
0
6
102
0.59
0.62
1.2
1.2
1.03
1.53
nmol/l
—
6
91
6
105
0.57
0.61
1.0
1.2
—
—
—
0
0
9
137
0.66
0.60
1.8
1.2
—
—
—
0
0
9
140
0.64
0.60
1.1
1.1
—
—
—
0
0
28
356
0.78
0.60
2.8
4.6
5.22
5.02
kpa
0.40
28
348
637
6629
0.94
0.60
4.7
4.3
0.00
0.00
estimate
0.80
80
1203
0
21
0.00
0.60
0.0
1.0
—
30.44
—
0
16
0
21
0.00
0.60
0.0
1.0
—
93.68
—
0
12
28
355
0.79
0.59
2.8
4.6
2.74
2.85
mmol/l
0.10
22
238
968
9407
1.06
0.59
5.7
5.3
2024.35
1639.45
e6/l
0.11
40
168
0
23
0.00
0.58
0.0
1.1
—
—
—
0
0
6
35
1.72
0.57
1.2
1.3
—
—
—
0
0
547
5235
1.06
0.57
4.4
3.9
5.82
5.85
ph
0.05
17
239
92
1040
0.88
0.57
2.4
3.6
7.43
7.40
ph
—
7
125
6
36
1.67
0.56
1.5
1.3
—
—
—
0
0
44
366
1.21
0.55
1.2
1.2
—
—
—
0
0
170
1563
1.10
0.52
2.6
2.5
6.77
6.35
ug/l
0.08
113
1272
6
96
0.62
0.52
1.3
1.4
—
—
—
0
0
9
132
0.68
0.52
1.4
1.2
—
—
nmol/l
—
0
0
10
145
0.69
0.50
1.1
1.1
—
—
—
0
0
7
107
0.65
0.48
1.0
1.5
—
—
—
0
0
647
6690
0.95
0.48
4.6
5.6
1.22
1.21
mmol/l
1.88
555
5983
61
698
0.87
0.47
2.2
1.8
1.36
2.45
ug/l
0.57
45
582
7
47
1.49
0.47
1.7
2.2
—
—
—
0
0
5
82
0.61
0.45
6.8
1.9
1.29
1.13
e9/l
—
5
76
634
6551
0.95
0.45
6.0
5.8
0.00
0.00
estimate
-0.00
81
1214
481
4621
1.05
0.45
3.8
4.2
—
—
—
0
0
13
175
0.74
0.44
1.8
3.7
—
—
—
0
0
11
78
1.41
0.43
1.9
1.7
0.17
3.32
u/field
—
6
54
92
1015
0.90
0.42
4.0
3.6
—
—
—
0
0
5
33
1.52
0.41
1.4
1.3
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
0.59
—
0
5
0
16
0.00
0.41
0.0
1.3
—
156.00
—
0
7
0
16
0.00
0.41
0.0
1.8
—
0.25
—
0
11
0
18
0.00
0.40
0.0
1.4
—
—
—
0
0
35
411
0.85
0.40
1.2
1.5
294.64
270.43
ug/g
0.32
22
253
44
507
0.86
0.40
2.1
2.9
0.18
0.28
g/l
—
8
186
109
999
1.10
0.39
1.4
1.4
—
—
—
0
0
0
19
0.00
0.39
0.0
1.2
—
1.81
—
0
19
68
759
0.89
0.39
2.3
3.7
—
—
—
0
0
9
66
1.37
0.38
1.9
3.3
13.44
13.26
%
—
9
66
29
341
0.85
0.35
2.1
3.9
—
—
—
0
0
6
44
1.36
0.34
1.0
1.0
—
—
—
0
0
22
182
1.21
0.33
2.0
2.2
1.83
2.77
u/field
—
6
48
6
86
0.70
0.33
1.0
1.1
—
—
—
0
0
221
2320
0.95
0.31
1.6
1.9
29.51
30.04
s
0.68
212
2235
7
99
0.71
0.30
1.0
1.1
—
—
—
0
0
7
99
0.71
0.30
1.0
1.1
—
—
—
0
0
642
6570
0.97
0.29
4.6
4.3
0.00
0.00
estimate
0.69
91
1348
45
503
0.89
0.29
4.3
3.6
—
—
—
0
0
12
150
0.80
0.27
1.1
1.2
—
—
—
0
0
5
73
0.68
0.26
1.0
1.1
—
5.97
—
0
13
730
7440
0.97
0.26
4.9
6.3
1.22
1.21
mmol/l
4.21
607
6224
534
5462
0.97
0.24
1.9
2.2
77.95
79.66
nmol/l
0.60
432
4702
11
88
1.25
0.22
4.8
3.8
—
—
—
0
0
5
40
1.25
0.22
1.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
6.53
—
0
5
0
13
0.00
0.21
0.0
10.7
—
6.25
—
0
13
989
10010
0.98
0.20
20.9
23.4
330.60
330.28
g/l
0.51
931
9828
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
12
99
1.21
0.19
1.1
1.1
—
—
—
0
0
447
4566
0.97
0.19
2.5
2.1
280.05
215.21
u/l
0.92
408
4234
31
343
0.90
0.19
2.0
2.3
19.03
76.83
ug/min
3.95
14
201
536
5264
1.02
0.18
3.7
3.7
—
—
—
0
0
150
1558
0.96
0.17
4.4
4.5
—
—
—
0
0
39
360
1.08
0.16
1.2
1.2
—
—
—
0
0
15
172
0.87
0.15
4.4
3.5
—
—
—
0
0
14
161
0.87
0.15
1.3
1.3
281.60
275.29
mosm/kgh2o
—
5
107
8
100
0.80
0.13
3.1
2.3
—
—
—
0
0
60
571
1.05
0.12
2.0
2.2
1452.82
505.07
ug/l
0.90
52
531
60
628
0.95
0.11
2.6
4.0
24.22
24.98
mmol/l
1.63
53
552
12
106
1.13
0.09
2.1
2.3
732.14
636.38
ml
—
7
63
10
114
0.88
0.09
5.4
16.9
—
—
—
0
0
11
124
0.89
0.09
1.1
1.1
—
—
—
0
0
6
55
1.09
0.09
3.3
6.7
—
—
—
0
0
5
65
0.77
0.08
6.8
1.8
75.60
71.18
%
—
5
60
7
82
0.85
0.07
1.4
1.8
—
—
—
0
0
7
83
0.84
0.07
1.4
2.0
1.04
3.06
ug/l
—
7
75
9
84
1.07
0.07
2.0
1.8
72.89
92.42
umol/l
—
9
84
61
625
0.98
0.04
5.8
4.2
—
—
—
0
0
15
149
1.01
0.00
1.1
1.2
233.00
143.86
miu/ml
—
5
51
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
62
0.97
-0.00
1.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
2.30
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
5.0
—
382.00
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
68
0.88
-0.00
1.2
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
33.50
—
0
6
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
5
58
0.86
-0.00
2.2
2.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
13.7
—
307.17
—
0
6
0
9
0.00
-0.00
0.0
11.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
4.3
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: AD_EO – Alzheimer’s disease (Early onset)

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).