nodular goiter: Goiter characterized by discrete tissue mass(es) that may or may not produce thyroid hormones.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
2981 |
4. Check minimum number of eventsNone |
2981 |
5. Include endpointsNone |
2981 |
6. Filter based on genotype QC (FinnGen only) |
2884 |
Control definitions (FinnGen only)
- Control exclude
- E4_THYROID
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- E04
- Name in latin
- Struma atoxica uninodularis
Similar endpoints
↥List of similar endpoints to
Nontoxic single thyroid nodule
based on the number of shared cases.
Similar with more cases:
- Nontoxic goitre/thyroid nodule
- Disorders of the thyroid gland
- Used for control exclusion in common control thyroid runs
- Endocrine, nutritional and metabolic diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 17821 | 14391 | 3351 |
| Only index persons | 16839 | 13735 | 3104 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.35 | 0.41 | 0.09 |
| Only index persons | 0.43 | 0.50 | 0.12 |
| Median age at first event (years) | |||
| Whole population | 51.50 | 50.54 | 55.53 |
| Only index persons | 50.93 | 50.05 | 54.82 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2884 | 2332 | 552 |
| Unadjusted period prevalence (%) | 0.72 | 0.83 | 0.25 |
| Median age at first event (years) | 51.58 | 49.65 | 59.74 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 2981
- Matched controls
- 29810
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D44.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Thyroid gland
56.1
307.7
271
53
E04.1
ICD-10 Finland
Nontoxic single thyroid nodule
6983.9
307.7
2587
28
E03
ICD-10 Finland
Other hypothyroidism
84.2
307.7
233
30
E04.2
ICD-10 Finland
Nontoxic multinodular goitre
218.4
307.7
740
45
T86
ICPC
Hypothyroidism/myxoedema
62.8
307.7
183
31
BA1AE
NOMESCO Finland
Thyroiid ultrasound examination
49.9
307.7
305
68
2410A
ICD-9 Finland
Non-toxic nodular goitre, Non-toxic uninodular goitre
+∞
307.7
318
*
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
127.5
307.7
560
54
E03.89
ICD-10 Finland
Other specified hypothyroidism
92.6
307.7
199
23
H03AA01
ATC
levothyroxine sodium; systemic
60.4
307.7
1282
368
BAA40
NOMESCO Finland
Unilateral lobectomy of thyroid gland
434.6
307.7
969
33
E04.9
ICD-10 Finland
Nontoxic goitre, unspecified
65.9
307.7
410
72
104
Kela drug reimbursment
Thyroid insufficiency
658.9
307.7
450
8
BA3AT
NOMESCO Finland
Cytology of thyroid with ultrasound quidance
56.2
307.7
421
87
EP1AE
NOMESCO Finland
Neck ultrasound examination
9.8
307.7
543
662
E04.0
ICD-10 Finland
Nontoxic diffuse goitre
187.0
307.7
176
10
D34
ICD-10 Finland
Benign neoplasm of thyroid gland
50.8
291.0
168
35
2504
FHL
Unilateral resection or enucleation
334.8
272.2
272
9
E89.01
ICD-10 Finland
Postsurgical hypothyroidism
2533.1
255.8
244
*
BAA60
NOMESCO Finland
Total thyroidectomy
486.0
229.3
226
5
H03BB01
ATC
carbimazole; oral
55.3
215.1
122
23
C73.91
ICD-10 Finland
Papillary carcinoma of the thyroid gland (thyroid gland)
323.5
180.2
181
6
8260/3-C73.9
ICD-O-3
Papillary adenocarcinoma, NOS, of thyroid gland
509.2
147.9
146
*
BAA20
NOMESCO Finland
Unilateral partial excision of thyroid gland
269.9
127.1
129
5
2505
FHL
Bilateral resection (also used if total removal has been performed on the other side)
215.4
101.2
104
5
R22.1
ICD-10 Finland
Localized swelling, mass and lump, neck
4.9
101.1
234
509
E04
ICD-10 Finland
Other nontoxic goitre
44.7
96.0
57
13
2462A
ICD-9 Finland
Other disorders of thyroid, Cyst of thyroid
+∞
90.0
86
*
E05.0
ICD-10 Finland
Thyrotoxicosis with diffuse goitre
894.6
89.2
87
*
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
8.0
83.2
114
147
E05.9
ICD-10 Finland
Thyrotoxicosis, unspecified
147.5
81.4
86
6
XX7CT
NOMESCO Finland
Radioiodine therapy of thydoid tissue
809.8
80.8
79
*
BA1AE, ,
SPAT
10.0
74.2
85
87
E05.2
ICD-10 Finland
Thyrotoxicosis with toxic multinodular goitre
256.4
73.7
75
*
T81
ICPC
Goitre
22.4
57.1
42
19
JN5PN
NOMESCO Finland
Isotope imaging of secondary neoplasms of thyroid origin
+∞
55.4
53
*
C73.92
ICD-10 Finland
Follicular carcinoma of the thyroid gland
281.4
54.4
55
*
E04.8
ICD-10 Finland
Other specified nontoxic goitre
90.0
48.0
53
6
EP1AE, ,
SPAT
4.8
42.1
96
205
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.8
41.6
218
812
C73.90
ICD-10 Finland
Malignant tumor of the thyroid gland (thyroid gland) without histology
111.6
40.8
44
*
E03.80
ICD-10 Finland
Hypothyroidism caused by autoimmune thyroiditis
76.3
40.0
45
6
8330/3-C73.9
ICD-O-3
Follicular carcinoma, NOS, of thyroid gland
392.5
39.2
39
*
Z01.8
ICD-10 Finland
Other specified special examinations
1.8
37.5
708
4393
24199
ICD-8 Finland
Non-toxic nodular goitre, Unspecified
+∞
36.5
35
*
A02BC05
ATC
esomeprazole; systemic
1.6
36.4
1258
9180
QX3LT
NOMESCO Finland
Subcutaneous sclerotherapy
69.1
36.0
41
6
BAA30
NOMESCO Finland
Excision of thyroid isthmus
182.1
34.8
36
*
E05.1
ICD-10 Finland
Thyrotoxicosis with toxic single thyroid nodule
+∞
33.4
32
*
TBA20
NOMESCO Finland
Aspiration cytology of thyroid gland
+∞
33.4
32
*
E05.80
ICD-10 Finland
Subacute thyrotoxicosis
36.8
31.5
40
11
XW1AT
NOMESCO Finland
Biopsy from other organ close to skin with ultrasound quidance
7.2
30.5
45
63
R13
ICD-10 Finland
Dysphagia
2.4
30.5
227
1001
E89.2
ICD-10 Finland
Postprocedural hypoparathyroidism
57.3
29.1
34
6
E06.1
ICD-10 Finland
Subacute thyroiditis
+∞
28.2
27
*
E07.9
ICD-10 Finland
Disorder of thyroid, unspecified
31.2
28.1
37
12
C73.99
ICD-10 Finland
Malignant tumor of the thyroid gland (thyroid gland), other or unspecified histology
141.3
26.6
28
*
106
Kela drug reimbursment
Hypoparathyroidism
40.5
25.8
32
8
BAA50
NOMESCO Finland
Lobectomy and resection of contralateral lobe of thyroid gland
262.9
25.7
26
*
C73
ICD-10 Finland
Malignant neoplasm of thyroid gland
136.2
25.6
27
*
BAA25
NOMESCO Finland
Bilateral partial excision of thyroid gland
+∞
25.0
24
*
E06.3
ICD-10 Finland
Autoimmune thyroiditis
26.4
24.8
34
13
E89.00
ICD-10 Finland
Postirradiation hypothyroidism
252.2
24.7
25
*
R49.08
ICD-10 Finland
Other specified dysphonia
3.2
22.5
89
283
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
2.8
21.7
110
403
N02BE01
ATC
paracetamol; systemic, rectal
1.8
21.5
2637
24230
E07.89
ICD-10 Finland
Other specified disorders of thyroid
50.4
21.1
25
5
T71
ICPC
Malignant neoplasm thyroid
+∞
20.9
20
*
E06.9
ICD-10 Finland
Thyroiditis, unspecified
37.5
20.8
26
7
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
20.2
1047
8059
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.8
20.1
313
1806
J37.0
ICD-10 Finland
Chronic laryngitis
2.6
19.9
113
439
2506
FHL
Thyroidectomy
201.3
19.6
20
*
4CJ01, ,
NOMESCO Finland
+∞
18.8
18
*
BAA99
NOMESCO Finland
Other operation on thyroid gland
+∞
18.8
18
*
T72
ICPC
Benign neoplasm thyroid
16.3
18.3
29
18
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.5
18.1
685
4931
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
18.0
796
5911
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.5
18.0
784
5809
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.5
17.9
597
4183
JN5AQ
NOMESCO Finland
SPECT of thyroid metastasis with low-dose CT
+∞
17.7
17
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.4
17.7
1005
7822
E89.09
ICD-10 Finland
Postprocedural hypothyroidism, other or several procedures
181.0
17.5
18
*
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
6.8
17.4
27
40
R49.01
ICD-10 Finland
Functional dysphonia
2.5
17.0
107
437
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
3.9
17.0
50
131
1930A
ICD-9 Finland
Malignant neoplasm of thyroid gland[CARCINOMA PAPILLARE THYREOIDEAE]
+∞
16.7
16
*
R07.4
ICD-10 Finland
Chest pain, unspecified
1.5
16.4
745
5547
BA2AT
NOMESCO Finland
Biopsy of thyroid with ultrasound quidance
40.3
16.3
20
5
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
16.1
700
5167
M54.5
ICD-10 Finland
Low back pain
1.4
15.8
997
7865
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.5
15.7
504
3494
M01AE02
ATC
naproxen; oral, rectal
1.4
15.2
1589
13576
SPAT1263
SPAT
Sampling
1.4
15.1
1129
9142
A06AC01
ATC
ispaghula (psylla seeds); oral
1.4
15.1
742
5595
Z00.0
ICD-10 Finland
General medical examination
1.5
14.8
511
3594
R03AC02
ATC
salbutamol; inhalant
1.4
14.8
1532
13048
UKC02
NOMESCO Finland
Cystoscopy
1.6
14.7
347
2240
BWD00
NOMESCO Finland
Reoperation for deep haemorrhage in endocrine surgery
+∞
14.6
14
*
2419X
ICD-9 Finland
Non-toxic nodular goitre, Unspecified non-toxic nodular goitre
+∞
14.6
14
*
R01AD09
ATC
mometasone; nasal
1.4
14.2
1277
10614
R51.80
ICD-10 Finland
Headache
1.5
14.0
428
2929
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
1.7
13.9
253
1525
J01FA10
ATC
azithromycin; systemic
1.3
13.8
1609
13887
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
1.9
13.8
168
895
T85
ICPC
Hyperthyroidism/thyrotoxicosis
23.9
13.8
19
8
S04
ICPC
Lump/swelling localized
1.7
13.7
286
1787
ZX114
NOMESCO Finland
Intramuscular
3.7
13.6
42
114
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.5
13.6
488
3456
BA1NN
NOMESCO Finland
I-131 dose capsel measurement
+∞
13.5
13
*
E03.0
ICD-10 Finland
Congenital hypothyroidism with diffuse goitre
+∞
13.5
13
*
R42
ICD-10 Finland
Dizziness and giddiness
1.4
13.5
611
4525
A11CC03
ATC
alfacalcidol; systemic
3.0
13.5
59
200
BA4KT
NOMESCO Finland
Sclerotherapy of thyroid
140.6
13.5
14
*
J01DB01
ATC
cefalexin; oral
1.4
13.4
2336
21419
EN1AD
NOMESCO Finland
CT examination of mouth and soft tissues of neck
4.0
13.3
37
93
R21
ICPC
Throat symptom/complaint
1.5
13.3
534
3864
E21.09
ICD-10 Finland
Other primary hyperparathyroidism
3.0
13.1
56
187
E05
ICD-10 Finland
Thyrotoxicosis [hyperthyroidism]
15.1
13.1
21
14
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.6
13.1
362
2423
A11CC02
ATC
dihydrotachysterol; oral
22.6
12.9
18
8
A77
ICPC
Viral disease other/NOS
2.3
12.8
94
413
A02BC02
ATC
pantoprazole; systemic
1.3
12.8
1909
16997
G44.2
ICD-10 Finland
Tension-type headache
1.5
12.7
389
2661
ZSB00
NOMESCO Finland
Procedure related to previous procedure classified in chapter B
32.2
12.6
16
5
8341/3-C73.9
ICD-O-3
Papillary microcarcinoma of thyroid gland
+∞
12.5
12
*
2411A
ICD-9 Finland
Non-toxic nodular goitre, Non-toxic multinodular goitre
+∞
12.5
12
*
8340/3-C73.9
ICD-O-3
Papillary carcinoma, follicular variant of thyroid gland
+∞
12.5
12
*
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.6
12.4
266
1675
C07AA05
ATC
propranolol; systemic
1.4
12.3
537
3943
Z50.5
ICD-10 Finland
Speech therapy
3.5
12.2
41
118
R01AD08
ATC
fluticasone; nasal
1.4
12.2
784
6151
BBA30
NOMESCO Finland
Excision of lesion of parathyroid gland
3.4
12.2
43
128
Z01.2
ICD-10 Finland
Dental examination
1.3
12.2
1234
10368
XKD00
NOMESCO Finland
Uroflowmetry
1.6
12.1
260
1637
G47.3
ICD-10 Finland
Sleep apnoea
1.5
12.1
500
3634
J01FA09
ATC
clarithromycin; systemic
1.4
12.0
854
6806
R52.9
ICD-10 Finland
Pain, unspecified
1.6
12.0
261
1648
R53
ICD-10 Finland
Malaise and fatigue
1.4
12.0
597
4488
C05AA08
ATC
fluocortolone; rectal, topical
1.5
11.9
367
2512
R49.8
ICD-10 Finland
Other and unspecified voice disturbances
3.5
11.8
40
116
L03
ICPC
Low back symptom/complaint
1.4
11.5
747
5865
E05.89
ICD-10 Finland
Other thyrotoxicosis
+∞
11.5
11
*
H06.2*E05.9
ICD-10 Finland
Dysthyroid exophthalmos
+∞
11.5
11
*
ZXA05
NOMESCO Finland
Left side
1.4
11.4
645
4948
UJF32
NOMESCO Finland
Coloscopy
1.4
11.4
683
5289
GB1AA
NOMESCO Finland
Tracheal X-ray examination
120.5
11.4
12
*
E03.2
ICD-10 Finland
Hypothyroidism due to medicaments and other exogenous substances
120.5
11.4
12
*
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
11.3
1282
10901
J01AA02
ATC
doxycycline; systemic
1.4
11.3
2217
20331
WZC00
NOMESCO Finland
Treatment plan or consultation
1.3
11.3
960
7843
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.5
11.3
362
2500
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.3
11.2
1388
11946
R07.0
ICD-10 Finland
Pain in throat
1.8
11.1
174
1005
K30
ICD-10 Finland
Functional dyspepsia
1.6
11.1
306
2045
M25.5
ICD-10 Finland
Pain in joint
1.3
11.0
883
7148
D25.9
ICD-10 Finland
Leiomyoma of uterus, unspecified
1.6
10.9
278
1824
ZXA00
NOMESCO Finland
Right side
1.4
10.8
688
5373
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.3
10.8
1563
13698
ZXE10
NOMESCO Finland
More than one and less than three hours
1.3
10.7
941
7715
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
1.8
10.6
163
936
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.6
10.6
231
1461
R00.2
ICD-10 Finland
Palpitations
1.7
10.6
212
1312
WZC30
NOMESCO Finland
Teaching
1.5
10.5
402
2874
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
3.5
10.4
35
101
E83.51
ICD-10 Finland
Hypocalcemia
5.4
10.4
20
37
R01AD12
ATC
fluticasone furoate; nasal
1.3
10.3
832
6733
WX402
NOMESCO Finland
General anaesthesia
1.4
10.2
545
4133
D17.1
ICD-10 Finland
Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
2.1
10.2
93
448
A02BC01
ATC
omeprazole; systemic
1.3
10.2
707
5593
M79.0
ICD-10 Finland
Rheumatism, unspecified
2.0
10.0
106
539
SPAT1153
SPAT
Removal of sutures
1.3
9.9
812
6574
EP2AT
NOMESCO Finland
Neck soft tissue cytology with ultrasound guidance
12.2
9.8
17
14
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.3
9.8
826
6711
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.4
9.8
545
4161
E21.0
ICD-10 Finland
Primary hyperparathyroidism
2.6
9.7
56
221
SPAT1312
SPAT
General health counselling
1.3
9.7
809
6565
M79.6
ICD-10 Finland
Pain in limb
1.3
9.5
1143
9727
R06.0
ICD-10 Finland
Dyspnoea
1.3
9.5
660
5212
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
9.5
1080
9126
N03AX16
ATC
[U] pregabalin
1.4
9.5
604
4710
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
1.6
9.4
213
1360
E89.0
ICD-10 Finland
Postprocedural hypothyroidism
+∞
9.4
9
*
A12AA04
ATC
calcium carbonate; oral
3.1
9.4
38
124
J02AC01
ATC
fluconazole; systemic
1.3
9.3
1180
10103
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
9.3
1962
17877
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.3
9.2
1149
9813
A98
ICPC
Health maint/preventive medicine
1.8
9.2
2868
27806
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.3
9.2
750
6061
M03BX02
ATC
tizanidine; oral
1.3
9.0
1712
15369
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
1.7
8.9
147
863
C07AB07
ATC
bisoprolol; oral
1.3
8.9
1191
10250
UJF30
NOMESCO Finland
Ileoscopy through colon
1.5
8.9
262
1777
K11.2
ICD-10 Finland
Sialoadenitis
2.0
8.7
85
421
SPAT1249
SPAT
Treatment-related counselling outside office
1.3
8.7
1010
8535
R12
ICD-10 Finland
Heartburn
1.6
8.6
205
1324
N06AX11
ATC
mirtazapine; oral
1.3
8.6
869
7215
P01AB01
ATC
metronidazole; oral, rectal
1.3
8.5
1120
9600
E06
ICD-10 Finland
Thyroiditis
27.6
8.5
11
*
A02BC04
ATC
rabeprazole; oral
1.5
8.4
236
1585
TEA00
NOMESCO Finland
Biopsy of lip
3.3
8.3
31
96
L01
ICPC
Neck symptom/complaint
1.4
8.3
413
3088
24110
ICD-8 Finland
Non-toxic nodular goitre, Sporadic
+∞
8.3
8
*
C739, ,
ICD-10 Finland
+∞
8.3
8
*
DFF00
NOMESCO Finland
Pure tone audiometry
1.5
8.3
246
1670
SPAT1375
SPAT
Structural ultrasound screening, weeks 18+0-21+6
3.6
8.3
26
72
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.3
8.3
1052
8975
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
2.6
8.3
45
173
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.3
8.3
736
6005
G04CB01
ATC
finasteride; oral
1.7
8.2
140
831
M70.6
ICD-10 Finland
Trochanteric bursitis
1.4
8.2
384
2846
-60
ICPC
Result test/procedure
1.7
8.2
143
855
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.3
8.1
568
4479
XA402
NOMESCO Finland
ENMG
2.2
8.1
67
311
T15
ICPC
THYROID LUMP/MASS
17.2
8.1
12
7
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
1.6
8.0
209
1380
BBA40
NOMESCO Finland
Subtotal parathyroidectomy
4.1
8.0
21
51
L72.1
ICD-10 Finland
Trichilemmal cyst
1.6
8.0
162
1007
M01AE03
ATC
ketoprofen; systemic, rectal
1.3
8.0
937
7911
SPAT1211
SPAT
Application of soft bandage
1.5
8.0
215
1430
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
1.6
8.0
173
1094
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.3
7.9
643
5178
M54.4
ICD-10 Finland
Lumbago with sciatica
1.4
7.9
453
3467
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
1.9
7.9
92
486
BA3AT, ,
SPAT
13.1
7.9
13
10
M01AH05
ATC
etoricoxib; oral
1.2
7.9
1701
15380
R02
ICPC
Shortness of breath/dyspnoea
1.4
7.8
306
2193
J01EA01
ATC
trimethoprim; systemic
1.3
7.8
741
6089
M01AB05
ATC
diclofenac; systemic, rectal
1.2
7.8
1806
16448
SPAT1310
SPAT
Counselling related to known health issue
1.3
7.8
798
6624
L13
ICPC
Hip symptom/complaint
1.3
7.7
497
3872
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.6
7.7
196
1287
R01AD58
ATC
fluticasone, combinations; nasal
1.3
7.6
620
4989
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.4
7.6
346
2547
H43.8
ICD-10 Finland
Other disorders of vitreous body
1.5
7.6
258
1799
H02AB06
ATC
prednisolone; systemic
1.2
7.6
1224
10698
N40
ICD-10 Finland
Hyperplasia of prostate
1.5
7.6
268
1884
UDH02
NOMESCO Finland
Rhinopharyngoscopy
1.6
7.6
161
1012
C07AB02
ATC
metoprolol; systemic
1.4
7.6
445
3417
PH2DE
NOMESCO Finland
Ultrasound examination of bloodflow in veins of lower extremity with Doppler method
2.0
7.5
75
376
A02BA02
ATC
ranitidine; systemic
1.3
7.5
469
3639
J01DA01
ATC
[U] cefalexin
1.2
7.4
1656
14981
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
2.2
7.4
58
265
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
2.0
7.3
72
359
E05.4
ICD-10 Finland
Thyrotoxicosis factitia
+∞
7.3
7
*
L15
ICPC
Knee symptom/complaint
1.3
7.2
631
5122
SPAT1058
SPAT
PEF monitoring instruction
1.5
7.2
204
1373
EP1AT
NOMESCO Finland
Punction of soft tissue of neck with ultrasound guidance
30.1
7.1
9
*
J01FA06
ATC
roxithromycin; oral
1.2
7.1
1054
9111
G43.9
ICD-10 Finland
Migraine, unspecified
1.6
7.1
142
880
XX9KE
NOMESCO Finland
Ultrasound examination with contrast
12.0
7.1
12
10
A04
ICPC
Weakness/tiredness general
1.4
7.0
337
2505
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.2
7.0
1256
11079
S18
ICPC
Laceration/cut
1.2
7.0
1156
10109
R4110, ,
SPAT
1.5
7.0
223
1539
R03BA05
ATC
fluticasone; inhalant
1.3
6.9
447
3479
H25.8
ICD-10 Finland
Other senile cataract
1.5
6.9
251
1775
R49.03
ICD-10 Finland
Atrophic dysphonia
2.9
6.8
30
103
M01AH01
ATC
celecoxib; oral
1.3
6.8
458
3585
J05AB01
ATC
aciclovir; systemic
1.3
6.8
577
4663
C08CA05
ATC
nifedipine; systemic
1.7
6.8
131
805
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.6
6.8
142
891
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
1.7
6.8
123
744
R01BA52
ATC
pseudoephedrine, combinations; oral
1.3
6.8
817
6895
2502
FHL
Thyroid exploration and possible biopsy
40.1
6.8
8
*
K07.60
ICD-10 Finland
Snapping jaw
1.6
6.7
140
877
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.4
6.7
309
2280
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.3
6.7
417
3229
A12AA06
ATC
calcium lactate gluconate; oral
22.6
6.7
9
*
H04.10
ICD-10 Finland
Dry eye syndrome
1.4
6.7
299
2197
UDC00
NOMESCO Finland
Ear microscopy
1.6
6.7
168
1102
R4135
NOMESCO Finland
Rehabilitation for hearing problems
2.4
6.6
42
175
G25.8
ICD-10 Finland
Other specified extrapyramidal and movement disorders
2.0
6.6
69
352
A02BC03
ATC
lansoprazole; oral
1.3
6.6
726
6059
G04CA02
ATC
tamsulosin; oral
1.4
6.6
303
2236
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
1.8
6.6
98
561
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
1.6
6.5
143
909
62630
ICD-8 Finland
Disorders of menstruation, Painful
2.9
6.5
29
101
R05
ICD-10 Finland
Cough
1.3
6.4
535
4310
PJD71
NOMESCO Finland
Extended sparing excision of cervical lymph nodes
5.7
6.4
17
30
F29
ICPC
Eye symptom/complaint other
1.4
6.4
234
1656
K11.5
ICD-10 Finland
Sialolithiasis
2.5
6.4
38
153
SAA02
NOMESCO Finland
Basic examination of mouth
1.2
6.4
1775
16301
Z85.8
ICD-10 Finland
Personal history of malignant neoplasms of other organs and systems
14.3
6.4
10
7
J01MA02
ATC
ciprofloxacin; systemic
1.2
6.4
934
8042
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.2
6.4
1177
10381
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.4
6.4
253
1820
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
1.4
6.3
357
2724
J01CA04
ATC
amoxicillin; systemic
1.3
6.3
2253
21229
8290/3-C73.9
ICD-O-3
Oxyphilic adenocarcinoma of thyroid gland
+∞
6.3
6
*
E03.8
ICD-10 Finland
Other specified hypothyroidism
+∞
6.3
6
*
HMAK, ,
NOMESCO Finland
1.4
6.2
281
2067
R4130
NOMESCO Finland
Speech therapy
2.1
6.1
57
279
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.3
6.1
631
5221
D24
ICD-10 Finland
Benign neoplasm of breast
2.0
6.1
62
314
DE2BG
NOMESCO Finland
Acoustic channel MRI examination with high intensity magnet
2.8
6.0
29
105
DAX00
NOMESCO Finland
Adjustment or review of hearing aid
1.7
6.0
112
682
DAX08
NOMESCO Finland
Fitting of hearing aid
1.7
6.0
116
713
L57.0
ICD-10 Finland
Actinic keratosis
1.4
6.0
241
1736
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
502
780
7.54
317.76
4.0
1.6
4.57
4.43
pmol/l
2.41
455
685
486
570
9.99
307.65
1.5
1.3
—
—
—
0
0
183
70
27.79
267.90
6.4
1.2
176.04
287.15
u/ml
—
59
8
2670
19017
4.87
175.84
6.6
2.6
15.32
14.42
pmol/l
59.00
2514
17142
387
1233
3.46
99.07
1.3
1.1
90.79
74.95
iu/ml
0.39
131
390
153
246
6.50
91.46
1.5
1.1
3.75
1.88
iu/l
1.05
35
46
2787
23202
4.09
88.96
7.9
3.5
1.87
2.06
mu/l
0.64
2624
21169
1773
12141
2.14
85.91
6.4
6.1
1.22
1.22
mmol/l
0.13
1509
10310
1560
10972
1.88
61.25
5.4
5.5
1.22
1.22
mmol/l
0.42
1426
9974
2248
18690
1.82
42.33
4.5
4.1
11.07
12.48
mm/h
5.82
2087
17279
367
1754
2.25
41.19
2.9
3.6
64.16
88.32
ng/l
10.52
302
1501
1435
10704
1.66
38.86
2.4
2.2
80.86
78.64
nmol/l
2.24
1283
9622
530
3094
1.87
33.81
4.8
4.4
33.18
32.93
%
0.21
387
2054
2223
19311
1.59
26.07
7.7
7.4
76.13
77.45
u/l
0.84
2107
18129
1159
8882
1.50
23.88
3.7
3.4
38.92
96.05
ng/l
0.53
771
5821
1476
11898
1.48
23.48
2.4
2.5
—
—
—
0
0
1466
11922
1.45
21.56
5.9
6.1
28.86
28.13
%
1.86
1372
11172
2603
23841
1.72
21.31
13.7
12.3
80.26
81.07
ml/min/173m2
1.26
2277
19561
1447
11780
1.44
20.91
5.6
5.8
56.47
57.22
%
1.69
1358
11017
1430
11632
1.44
20.67
5.9
6.3
8.32
8.42
%
0.62
1336
10878
2711
25166
1.85
20.61
14.3
13.3
18.19
23.06
mg/l
14.23
2210
19707
1008
7707
1.47
20.10
2.5
2.5
55.35
69.77
u/l
0.77
941
7106
1539
12731
1.43
20.04
5.7
6.0
0.19
0.19
e9/l
0.14
1380
11147
1418
11570
1.43
19.85
5.7
6.0
2.84
2.81
%
0.22
1320
10800
335
1994
1.77
19.37
4.3
3.5
1.23
1.23
mmol/l
0.08
305
1729
1089
8522
1.44
18.90
2.9
3.4
2.34
2.36
mmol/l
4.75
943
7461
1483
12305
1.41
18.30
5.6
5.8
0.04
0.04
e9/l
0.20
1325
10602
2643
24499
1.70
18.27
5.0
4.4
5.84
5.85
mmol/l
0.15
2405
22344
1479
12273
1.41
18.21
5.6
5.8
0.56
0.56
e9/l
0.30
1328
10582
343
2092
1.72
18.16
2.4
2.0
365.17
370.66
nmol/l
0.21
314
1918
1513
12627
1.40
17.89
5.7
5.8
1.87
1.92
e9/l
0.75
1370
11157
2757
25889
1.86
17.88
15.9
14.8
139.90
139.70
mmol/l
4.06
2699
25223
2762
25965
1.87
17.64
16.0
15.0
3.93
3.95
mmol/l
2.71
2698
25236
1361
11204
1.40
17.18
5.8
6.0
0.70
0.68
%
0.76
1259
10433
1657
14147
1.39
16.53
3.9
4.3
6.50
6.59
mmol/l
1.27
1574
13181
2670
24931
1.68
16.49
4.8
4.2
4.78
4.80
mmol/l
0.55
2462
23091
2573
23830
1.58
16.18
4.3
3.8
1.27
1.26
mmol/l
0.43
2345
21762
1531
12961
1.37
15.77
5.6
6.0
10.39
10.81
umol/l
1.01
1442
12302
2823
26841
1.98
15.71
11.1
10.2
24.44
24.49
u/l
0.06
2727
25875
2489
22921
1.52
15.66
5.9
5.3
39.17
39.23
mmol/mol
0.12
2290
21169
1865
16311
1.38
15.61
3.1
3.0
42.38
44.79
u/l
0.70
1729
15136
2651
24769
1.63
15.58
4.8
4.2
1.53
1.55
mmol/l
2.13
2433
22814
801
6103
1.43
15.42
2.2
2.2
—
—
—
0
0
926
7250
1.40
15.23
2.0
2.1
144.49
198.40
u/l
2.47
864
6792
1322
10975
1.37
15.18
11.4
13.6
1.19
1.23
inr
1.00
407
3170
2701
25398
1.68
14.95
5.2
4.7
2.83
2.83
mmol/l
0.04
2479
23390
620
4584
1.45
13.86
1.3
1.3
21.27
32.67
iu/ml
4.05
190
1481
831
6471
1.39
13.85
3.2
2.8
1004.99
1170.44
ng/l
0.81
705
5518
589
4350
1.44
13.17
1.3
1.2
7.24
11.57
u/ml
1.17
230
1689
1654
14408
1.33
12.96
8.6
9.1
3.87
4.01
e9/l
2.23
1489
12556
1271
10673
1.33
12.78
3.1
2.7
112.58
110.86
ug/l
0.10
1178
9901
2901
28040
2.29
12.54
22.2
19.6
257.68
258.30
e9/l
0.21
2850
27314
102
469
2.22
12.49
3.5
3.1
7.03
7.55
mmol/l
1.10
102
463
2902
28064
2.29
12.35
22.2
19.7
134.73
133.30
g/l
7.98
2875
27654
2901
28054
2.27
12.28
22.1
19.6
6.49
6.64
e9/l
2.94
2844
27230
2901
28057
2.27
12.23
22.1
19.6
4.49
4.43
e12/l
9.70
2842
27244
104
492
2.15
11.88
3.5
3.0
1.41
1.57
mmol/l
1.41
104
483
2895
28010
2.16
11.62
21.9
19.6
39.83
39.64
%
0.88
2773
26173
719
5640
1.36
11.05
1.3
1.3
0.93
1.58
u/ml
2.12
188
1464
95
449
2.15
10.90
2.3
1.8
5.52
4.96
mmol/24h
0.65
80
388
1183
10049
1.29
10.19
2.0
1.9
99.99
96.81
pmol/l
1.33
603
4925
204
1265
1.66
10.08
2.7
3.6
1.60
1.95
mmol/l
0.75
140
956
1280
11018
1.28
9.83
9.7
9.0
0.00
0.00
e9/l
1.00
1115
8927
212
1341
1.63
9.69
2.8
3.6
5.08
5.18
kpa
1.02
200
1276
146
838
1.78
9.56
2.9
4.0
24.84
25.02
mmol/l
0.34
133
774
640
5037
1.34
9.43
1.7
1.6
44055018.68
45714039.98
pmol/l
0.02
513
4176
1401
12347
1.25
8.35
5.8
4.9
0.00
0.00
estimate
0.80
278
2197
1093
9381
1.26
8.13
4.4
3.8
—
—
—
0
0
155
951
1.66
8.03
4.3
3.7
45.68
48.81
%
0.91
155
942
1411
12482
1.25
8.01
4.2
3.7
0.00
0.00
estimate
1.08
278
2191
47
192
2.47
7.65
1.2
1.2
72.50
61.73
u/ml
—
6
11
405
3081
1.36
7.32
2.2
2.2
103.48
111.18
ug/g
0.25
307
2413
157
993
1.61
7.24
1.8
1.9
—
—
—
0
0
530
4208
1.32
7.17
1.7
1.7
1042.20
1177.45
nmol/l
2.87
407
3161
1383
12312
1.23
7.07
4.2
3.7
0.00
0.00
estimate
1.23
308
2357
16
23
6.99
6.99
1.9
1.2
—
—
—
0
0
230
1598
1.48
6.94
1.3
1.3
22.84
51.95
au/ml
—
8
95
121
725
1.70
6.89
1.4
1.2
26.26
32.88
u/ml
—
9
43
680
5608
1.28
6.85
1.5
1.5
20.93
20.92
nmol/l
0.01
579
4720
72
368
1.98
6.84
1.2
1.4
24.30
31.17
u/l
0.81
59
307
249
1763
1.45
6.82
2.4
2.3
19.75
25.63
au/ml
0.50
16
134
111
656
1.72
6.66
1.4
1.3
1.70
7.90
u/ml
0.74
14
67
112
665
1.71
6.61
1.4
1.3
2.86
4.75
u/ml
0.95
25
118
83
454
1.85
6.46
1.2
1.3
13.57
13.52
u/l
0.01
69
369
839
7142
1.24
6.37
4.0
3.7
10.08
8.37
mg/mmol
0.30
487
4265
592
4865
1.27
6.06
1.5
1.4
2.24
2.38
g/l
1.05
370
2883
701
5884
1.25
5.98
2.2
2.2
2.94
2.98
mg/l
0.18
606
5022
378
2933
1.33
5.97
5.3
5.3
1.03
1.04
mmol/l
0.25
343
2715
68
359
1.92
5.93
1.5
1.4
—
—
—
0
0
115
709
1.65
5.93
1.3
1.4
327.67
288.51
ug/g
1.43
62
394
279
2068
1.39
5.92
1.9
1.9
—
—
—
0
0
190
1332
1.46
5.52
3.4
3.0
130.35
127.55
g/l
1.07
190
1307
138
907
1.55
5.47
1.7
1.8
—
—
—
0
0
50
245
2.06
5.40
1.3
1.2
—
—
—
0
0
832
7201
1.22
5.21
3.2
3.1
6.95
7.00
mmol/l
0.14
703
6048
89
532
1.69
5.20
1.3
1.2
1.14
4.14
u/ml
—
9
41
127
834
1.55
5.08
2.0
2.0
12.07
11.65
nmol/l
0.20
108
732
466
3804
1.27
4.99
3.1
3.2
0.83
0.81
mmol/l
1.57
438
3562
1807
16817
1.19
4.96
5.0
4.4
1944.30
2236.10
e6/l
0.08
20
202
124
817
1.54
4.90
2.1
2.1
4063.02
4429.22
u/l
0.06
43
328
121
794
1.55
4.87
1.9
1.9
—
—
—
0
0
149
1024
1.48
4.83
1.3
1.3
0.22
1.01
u/ml
1.69
13
96
147
1009
1.48
4.79
2.9
2.6
0.64
0.65
%
0.23
147
1004
23
84
2.75
4.77
1.9
1.3
145.04
73.87
nmol/24h
0.45
23
84
655
5583
1.22
4.72
2.1
1.7
0.96
1.10
mg/l
0.79
522
4254
301
2341
1.32
4.68
1.9
2.0
—
—
—
0
0
148
1029
1.46
4.54
2.9
2.7
1.12
1.20
%
0.36
148
1021
257
1964
1.34
4.52
4.3
3.6
1.89
2.03
mmol/l
0.30
229
1682
64
364
1.77
4.50
1.3
1.3
0.22
0.42
nmol/l
—
5
21
779
6782
1.20
4.49
3.3
3.2
609.82
375.79
mg/l
0.49
434
4072
214
1595
1.37
4.43
1.2
1.3
102.73
201.69
u/ml
3.41
191
1474
1171
10591
1.17
4.30
4.0
4.6
36.04
35.59
g/l
2.30
1084
9842
275
2144
1.31
4.22
3.5
3.1
0.83
0.77
ug/l
0.26
194
1469
143
1007
1.44
4.13
1.7
2.0
38.81
39.55
u/l
0.18
127
901
823
7247
1.19
4.13
3.5
3.1
26.42
69.63
e6/l
3.01
663
5433
54
300
1.81
4.13
1.7
1.5
—
—
—
0
0
54
305
1.78
3.93
1.8
1.5
—
—
—
0
0
53
298
1.79
3.92
1.5
2.1
28.43
25.92
mg/l
—
10
73
53
299
1.79
3.88
1.8
1.5
—
—
—
0
0
52
294
1.78
3.78
1.8
1.5
—
—
—
0
0
52
294
1.78
3.78
1.8
1.5
—
—
—
0
0
52
294
1.78
3.78
1.8
1.5
—
—
—
0
0
179
1344
1.35
3.59
1.1
1.0
—
—
—
0
0
241
1889
1.30
3.59
2.3
2.7
67.04
66.57
g/l
0.50
214
1720
394
3278
1.23
3.56
2.5
2.3
2.37
2.35
g/l
0.42
365
3037
25
112
2.24
3.48
2.1
1.6
4.89
4.25
nmol/l
0.09
19
91
439
3710
1.21
3.40
5.7
5.1
2.48
2.88
ug/l
0.57
389
3295
522
4491
1.20
3.35
1.6
1.5
—
—
—
0
0
25
115
2.18
3.28
1.8
1.8
—
—
—
0
0
29
142
2.05
3.26
1.6
1.3
—
—
—
0
0
13
40
3.26
3.13
1.8
1.4
118.62
90.67
ng/l
0.27
13
40
422
3585
1.21
3.10
2.6
2.4
13.13
13.17
umol/l
0.04
393
3342
111
792
1.42
3.07
1.9
1.8
—
—
—
0
0
682
6052
1.16
3.01
2.5
2.4
8414.63
4793.24
umol/l
0.96
588
5296
35
191
1.84
2.92
2.2
2.0
2.15
2.05
u/field
0.04
13
73
79
534
1.49
2.91
3.0
3.3
26.02
26.82
mg/l
0.05
40
327
68
449
1.53
2.80
2.3
2.8
8.26
8.14
kpa
0.23
68
440
218
1748
1.27
2.77
1.6
1.7
—
—
—
0
0
297
2472
1.22
2.70
2.9
3.2
—
—
—
0
0
360
3059
1.20
2.65
2.6
2.4
22.57
22.74
%
0.10
321
2610
351
2980
1.20
2.61
4.6
4.4
21.18
21.16
%
0.01
190
1486
96
690
1.40
2.60
1.3
1.3
—
—
—
0
0
721
6509
1.14
2.47
4.5
4.1
0.00
0.00
estimate
1.28
276
2166
15
63
2.39
2.46
1.1
1.1
5.29
14.12
u/ml
—
9
45
1676
15929
1.12
2.42
3.0
2.9
—
—
—
0
0
220
1798
1.24
2.40
2.7
2.7
10.19
10.44
g/l
0.48
197
1653
60
404
1.50
2.31
1.1
1.1
5.96
4.64
u/ml
0.17
30
197
75
532
1.42
2.23
2.2
2.9
24.27
24.90
mmol/l
0.64
75
520
291
2468
1.20
2.22
2.2
2.5
1.72
1.81
%
0.80
260
2192
10
35
2.86
2.20
1.6
1.6
—
—
—
0
0
433
3800
1.16
2.20
3.0
2.7
3.31
3.37
e6/l
0.04
286
1979
21
107
1.97
2.20
1.8
1.4
—
—
—
0
0
21
107
1.97
2.20
1.8
1.4
—
—
—
0
0
76
543
1.41
2.18
1.7
1.4
—
—
—
0
0
77
552
1.41
2.17
1.4
1.2
26.72
44.41
u/ml
—
9
70
19
94
2.03
2.15
1.1
1.2
159.53
145.61
mmol/24h
0.38
19
94
223
1849
1.22
2.15
2.8
3.7
89.12
56.21
u/ml
0.25
215
1787
104
786
1.33
2.12
2.0
1.7
1.15
1.18
g/l
0.47
93
744
298
2547
1.19
2.10
5.5
4.1
235.00
249.44
u/l
0.90
277
2406
101
764
1.33
2.06
2.0
1.7
0.23
0.23
g/l
0.35
91
723
19
97
1.96
2.00
2.3
1.7
—
—
—
0
0
19
97
1.96
2.00
2.3
1.7
—
—
—
0
0
19
97
1.96
2.00
2.3
1.7
—
—
—
0
0
175
1430
1.24
1.96
2.1
1.8
1.39
1.39
g/l
0.00
155
1312
17
84
2.03
1.95
1.3
1.6
0.55
0.37
ug/l
0.76
11
58
95
719
1.33
1.94
1.5
1.3
—
—
—
0
0
36
226
1.60
1.93
2.9
2.7
—
—
—
0
0
317
2746
1.17
1.92
3.5
4.0
22.25
19.02
ug/l
0.11
243
2192
559
5051
1.13
1.87
2.9
2.5
7.98
6.57
e6/l
0.41
501
4481
218
1835
1.20
1.84
2.2
2.6
70.85
70.63
e9/l
0.03
171
1353
873
8102
1.11
1.83
3.0
3.2
32.45
33.04
u/l
0.09
832
7697
5
12
4.17
1.82
1.2
1.3
199.00
329.75
u/l
—
5
12
19
102
1.87
1.76
1.7
2.1
20.51
97.57
ug/l
0.50
19
91
14
67
2.09
1.76
1.1
1.2
180.42
146.09
pmol/l
0.50
14
67
14
67
2.09
1.76
4.1
3.2
—
—
—
0
0
34
517
0.65
1.70
3.6
6.5
105.59
105.09
mmol/l
0.33
29
460
25
149
1.68
1.66
1.2
1.5
81.72
76.07
umol/l
0.34
25
149
2241
21826
1.11
1.65
16.9
15.8
15.65
14.94
%
4.82
2206
21444
150
1232
1.23
1.65
1.4
1.3
29.48
32.84
iu/l
0.60
133
1073
424
3799
1.14
1.63
1.8
1.8
—
—
—
0
0
51
360
1.42
1.63
1.0
1.0
1.00
2.83
u/ml
1.96
15
156
25
150
1.67
1.63
1.7
1.3
—
—
—
0
0
5
14
3.58
1.61
1.2
1.1
—
—
—
0
0
734
6799
1.11
1.58
1.6
1.6
1.32
1.35
mmol/l
0.53
616
5724
6
20
3.00
1.58
1.0
1.1
—
—
—
0
0
90
700
1.29
1.57
2.9
3.2
1.38
1.82
ratio
—
8
50
92
720
1.29
1.54
2.9
3.2
44.70
60.67
mg/l
0.75
76
587
65
484
1.35
1.54
3.2
3.8
55.63
57.69
%
0.69
65
484
5
15
3.34
1.52
1.0
1.0
—
—
—
0
0
44
307
1.44
1.52
1.4
1.3
267.11
291.36
pmol/l
0.20
39
266
24
146
1.65
1.50
1.8
1.4
—
—
—
0
0
92
724
1.28
1.49
2.9
3.2
35.95
47.00
mg/l
0.56
75
592
722
6703
1.10
1.48
3.4
3.0
0.36
0.45
e6/l
0.68
583
4988
20
116
1.73
1.48
2.3
1.6
—
—
—
0
0
20
116
1.73
1.48
2.3
1.6
—
—
—
0
0
40
276
1.46
1.47
2.0
2.1
8.13
6.74
umol/l
0.18
25
193
81
630
1.29
1.44
1.8
2.1
10.64
11.60
mg/l
0.54
71
580
216
1866
1.17
1.41
2.2
2.3
7.01
6.41
ug/l
0.17
180
1622
78
606
1.29
1.40
1.8
1.7
—
—
—
0
0
96
766
1.26
1.40
1.7
1.5
1.44
7.89
iu/ml
0.40
21
159
114
928
1.24
1.40
2.4
2.3
3.64
3.63
g/l
0.01
103
842
108
875
1.24
1.39
2.4
2.4
2.84
2.97
g/l
0.71
98
789
62
468
1.33
1.37
1.1
1.1
1.51
2.09
u/ml
0.24
30
235
65
495
1.32
1.36
2.0
2.4
99.02
76.59
ug/min
0.34
38
292
23
359
0.64
1.35
1.3
1.5
—
—
—
0
0
106
860
1.24
1.35
2.4
2.3
10.17
10.26
g/l
0.07
93
769
157
1328
1.19
1.33
1.6
1.5
—
—
—
0
0
113
927
1.23
1.31
2.4
2.3
—
—
—
0
0
6
24
2.50
1.30
1.8
2.1
—
—
—
0
0
113
928
1.23
1.30
2.4
2.3
7.25
7.46
g/l
0.73
103
842
89
712
1.26
1.29
2.7
2.3
0.03
0.00
g/l
0.39
83
655
166
1416
1.18
1.28
1.6
1.6
—
—
—
0
0
5
18
2.78
1.28
1.2
1.3
—
—
—
0
0
52
387
1.35
1.28
1.1
1.1
1.27
1.06
u/ml
0.15
22
157
11
55
2.00
1.27
1.1
1.8
0.56
1.18
mmol/l
0.27
11
50
450
4115
1.11
1.26
2.8
2.5
1.03
1.39
e6/l
1.21
299
2279
98
796
1.24
1.25
2.5
2.4
0.85
0.92
g/l
0.08
87
699
18
107
1.69
1.25
2.3
2.5
—
—
—
0
0
6
25
2.40
1.24
1.3
3.0
1.33
0.80
u/field
—
6
25
60
460
1.31
1.22
1.4
1.2
—
—
—
0
0
60
461
1.31
1.21
2.0
2.6
16.13
15.89
%
0.17
34
226
6
26
2.31
1.18
1.0
1.0
—
—
—
0
0
94
766
1.23
1.18
1.3
1.3
253.70
226.55
miu/ml
0.30
47
369
19
117
1.63
1.18
2.4
3.0
971.74
881.89
u/ml
0.08
19
117
84
677
1.25
1.17
1.2
1.1
—
—
—
0
0
11
57
1.93
1.17
1.4
1.5
30.59
22.61
%
0.37
11
50
91
741
1.24
1.16
2.6
2.2
39.07
37.67
g/l
1.41
81
654
34
241
1.42
1.13
1.1
1.2
—
—
—
0
0
27
183
1.48
1.13
2.1
2.4
747.30
654.70
ml
0.54
20
124
32
225
1.43
1.12
2.7
3.7
—
—
—
0
0
51
388
1.32
1.12
1.1
1.1
—
—
—
0
0
212
1875
1.14
1.06
7.8
7.1
9.31
9.23
mmol/l
0.06
198
1803
395
3623
1.10
1.06
2.6
2.0
29.15
29.52
s
0.83
384
3500
118
1390
0.84
1.05
5.6
6.4
24.21
24.61
mmol/l
0.69
110
1307
567
5291
1.09
1.05
4.3
4.0
1.02
1.02
kg/l
0.52
107
798
11
60
1.84
1.02
1.4
1.5
0.50
3.11
%
1.36
11
50
113
959
1.19
0.98
1.6
1.7
3.74
4.05
mg/l
0.13
91
720
5
23
2.18
0.98
1.2
1.0
—
—
—
0
0
7
36
1.95
0.97
1.4
1.1
—
—
—
0
0
15
93
1.62
0.93
1.0
1.1
94.62
209.29
iu/ml
2.33
15
93
102
863
1.19
0.93
1.8
2.0
1.51
2.32
ug/l
0.52
85
772
12
70
1.72
0.92
1.3
1.5
60.50
65.86
%
0.22
12
56
87
726
1.20
0.92
1.1
1.1
0.88
6.42
u/ml
—
6
75
6
28
2.15
0.91
1.8
2.0
—
—
—
0
0
55
437
1.26
0.91
1.5
1.2
249.14
263.38
u/ml
0.17
36
261
80
663
1.21
0.91
2.8
2.4
0.00
0.00
g/l
-0.00
74
609
19
126
1.51
0.91
1.5
1.8
0.43
4.66
u/field
1.62
14
82
233
2582
0.89
0.91
5.0
6.8
5.04
5.11
kpa
0.63
218
2458
233
2581
0.89
0.90
5.0
6.8
13.53
12.69
kpa
1.35
218
2459
27
193
1.40
0.90
2.0
1.5
—
—
—
0
0
27
193
1.40
0.90
2.0
1.5
—
—
—
0
0
27
193
1.40
0.90
2.0
1.5
—
—
—
0
0
11
63
1.75
0.90
1.1
1.1
—
—
—
0
0
79
656
1.21
0.89
2.8
2.4
0.00
0.00
g/l
-0.00
74
608
19
127
1.50
0.88
1.1
1.1
—
—
—
0
0
22
152
1.45
0.88
1.1
1.1
0.16
18.40
nmol/l
—
7
25
35
263
1.33
0.87
1.1
1.0
—
—
—
0
0
45
352
1.28
0.85
1.4
1.4
0.31
0.40
nmol/l
0.60
33
265
233
2568
0.90
0.83
5.0
6.9
0.94
1.17
mmol/l
0.43
178
2022
214
2369
0.90
0.83
2.4
2.3
36.08
39.63
u/l
0.46
177
2013
496
4653
1.08
0.83
2.8
3.0
2.44
2.46
mmol/l
1.57
439
4090
19
129
1.48
0.83
2.2
1.5
0.99
1.30
nmol/l
0.51
14
96
568
5357
1.07
0.83
1.4
1.4
—
—
—
0
0
6
32
1.88
0.81
1.0
1.0
—
—
—
0
0
46
365
1.26
0.80
1.1
1.1
0.76
1.69
u/ml
0.69
22
170
16
106
1.51
0.78
2.4
3.3
—
—
—
0
0
27
199
1.36
0.78
1.2
1.2
—
—
titre
—
0
0
50
403
1.24
0.77
1.7
1.6
—
—
—
0
0
26
191
1.36
0.77
1.2
1.3
—
—
—
0
0
6
34
1.77
0.76
1.2
1.1
—
—
—
0
0
308
2845
1.09
0.76
2.4
2.7
6.31
7.74
umol/l
1.28
266
2457
30
226
1.33
0.76
2.7
3.5
54.36
56.14
%
0.13
25
194
5
24
2.09
0.74
3.2
2.2
—
—
—
0
0
46
369
1.25
0.74
2.6
3.6
3.02
1.45
%
0.74
40
332
255
2339
1.10
0.74
2.2
2.2
0.22
0.21
g/l
1.17
242
2206
8
133
0.60
0.73
1.0
1.2
—
—
—
0
0
324
3006
1.09
0.73
6.3
6.4
—
—
—
0
0
10
159
0.63
0.72
1.4
1.3
—
—
—
0
0
32
246
1.30
0.72
1.5
1.3
273.78
275.83
mosm/kgh2o
0.23
27
187
11
171
0.64
0.72
1.1
1.6
—
—
—
0
0
662
6310
1.06
0.71
3.5
3.6
93.85
92.96
%
0.42
647
6142
21
151
1.39
0.71
1.3
1.3
—
—
—
0
0
5
26
1.92
0.70
1.2
1.3
—
—
—
0
0
32
247
1.30
0.70
2.1
1.6
—
—
—
0
0
7
41
1.71
0.70
1.1
1.5
—
—
—
0
0
13
85
1.53
0.69
4.2
1.9
—
—
—
0
0
21
153
1.38
0.67
1.3
1.3
—
—
—
0
0
16
111
1.44
0.65
1.0
1.4
—
72.73
%
—
0
15
7
44
1.59
0.65
1.0
1.0
—
—
—
0
0
86
989
0.87
0.65
1.4
1.5
—
—
—
0
0
30
233
1.29
0.64
2.2
1.6
—
—
—
0
0
58
688
0.84
0.64
1.5
1.2
—
—
—
0
0
8
127
0.63
0.64
1.6
1.7
—
—
—
0
0
20
146
1.37
0.63
1.1
1.4
—
719.17
—
0
12
23
172
1.34
0.63
1.3
1.6
—
—
—
0
0
214
1965
1.10
0.63
5.0
6.6
1.21
1.32
mmol/l
1.06
209
1924
75
645
1.17
0.63
1.3
1.4
—
—
—
0
0
93
1059
0.87
0.62
1.5
1.5
—
—
—
0
0
5
30
1.67
0.61
1.0
1.4
—
—
—
0
0
40
326
1.23
0.59
1.4
1.3
24.02
45.67
u/ml
—
5
18
217
2001
1.09
0.59
2.9
2.5
66.18
66.98
ml/min/173m2
0.12
101
776
0
22
0.00
0.59
0.0
2.1
—
0.85
—
0
15
11
72
1.53
0.59
1.1
1.2
—
—
—
0
0
42
508
0.82
0.58
1.4
1.3
—
—
—
0
0
42
508
0.82
0.58
1.4
1.3
—
—
—
0
0
244
2627
0.92
0.58
1.7
1.7
—
—
—
0
0
19
140
1.36
0.58
3.8
2.6
0.27
0.21
e9/l
0.89
19
121
36
291
1.24
0.58
1.3
1.7
90.60
89.98
%
0.20
36
286
32
255
1.26
0.58
1.3
1.6
—
—
—
0
0
6
36
1.67
0.56
1.0
1.0
—
—
—
0
0
194
2105
0.92
0.56
5.2
7.7
121.26
120.00
g/l
0.36
188
2039
229
2126
1.08
0.55
1.7
1.7
—
—
—
0
0
41
339
1.21
0.54
1.0
1.1
48.00
29562.54
iu/ml
—
8
79
25
317
0.79
0.54
2.4
2.1
748.22
1223.55
u/ml
0.18
25
312
13
182
0.71
0.54
1.1
1.5
—
—
—
0
0
208
2244
0.92
0.53
5.2
7.4
96.46
95.94
%
0.93
197
2155
44
368
1.20
0.53
1.1
1.1
—
—
—
0
0
33
268
1.23
0.52
2.2
2.2
—
—
—
0
0
9
64
1.41
0.51
1.0
1.1
—
—
—
0
0
25
197
1.27
0.51
1.5
1.2
0.46
1.01
u/ml
—
10
101
15
109
1.38
0.51
1.1
1.5
—
—
—
0
0
63
547
1.16
0.50
1.6
1.5
—
—
—
0
0
45
380
1.19
0.50
1.1
1.1
—
—
—
0
0
66
754
0.87
0.49
1.2
1.2
—
—
—
0
0
19
145
1.31
0.48
1.2
1.6
7.79
8.09
mmol/l
0.23
19
137
25
199
1.26
0.48
1.2
1.1
—
—
—
0
0
25
200
1.25
0.46
1.2
1.1
—
—
—
0
0
50
430
1.17
0.46
1.2
1.2
—
—
—
0
0
40
338
1.19
0.45
1.3
1.2
21.64
43.70
u/l
1.16
35
285
69
776
0.89
0.43
1.7
1.8
—
—
—
0
0
12
87
1.38
0.42
12.7
13.9
0.67
0.60
mmol/l
0.96
12
79
12
87
1.38
0.42
1.4
2.6
—
34354.64
—
0
14
8
57
1.40
0.42
1.5
1.2
—
—
—
0
0
36
304
1.19
0.42
1.5
1.5
52.59
58.93
%
0.47
22
191
22
176
1.25
0.41
1.5
1.6
8.55
6.13
u/l
0.37
16
145
62
548
1.13
0.41
1.6
1.5
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
45.46
—
0
5
0
17
0.00
0.40
0.0
1.2
—
22.16
—
0
9
59
521
1.14
0.40
3.0
3.1
30.55
950.99
u/ml
1.16
52
475
36
306
1.18
0.39
1.3
1.5
—
—
—
0
0
38
325
1.17
0.39
1.1
1.4
—
—
—
0
0
21
169
1.24
0.38
1.1
1.1
—
—
—
0
0
44
382
1.15
0.38
1.2
1.2
8.63
5.04
u/ml
0.50
19
134
67
747
0.89
0.37
1.2
1.2
—
—
—
0
0
55
486
1.13
0.37
1.5
1.5
—
—
—
0
0
86
782
1.10
0.37
2.0
2.2
240.53
756.54
ug/l
1.15
77
730
5
77
0.65
0.35
3.4
2.4
110.60
147.44
nmol/l
—
5
66
18
144
1.25
0.35
1.0
1.4
—
54.67
—
0
15
51
575
0.88
0.35
1.3
1.5
—
—
—
0
0
24
199
1.21
0.35
1.2
1.1
—
—
—
0
0
16
200
0.80
0.34
1.5
1.5
6.23
6.55
mmol/l
0.20
16
191
24
200
1.20
0.33
1.2
1.1
—
—
—
0
0
24
200
1.20
0.33
1.2
1.1
—
—
—
0
0
12
155
0.77
0.33
1.3
1.3
1.66
1.62
g/l
0.15
12
155
42
477
0.88
0.33
1.8
1.6
—
—
—
0
0
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
10
74
1.35
0.32
1.2
1.1
115.40
117.45
%
—
10
69
43
486
0.88
0.32
1.3
1.5
—
—
—
0
0
7
52
1.35
0.31
2.1
4.2
—
—
—
0
0
7
52
1.35
0.31
2.1
4.2
—
—
—
0
0
36
411
0.87
0.31
1.5
1.7
—
—
—
0
0
42
372
1.13
0.30
1.8
1.4
—
—
—
0
0
42
372
1.13
0.30
1.8
1.4
—
—
—
0
0
22
185
1.19
0.29
1.3
1.6
—
—
—
0
0
52
468
1.11
0.29
1.5
1.3
—
19.60
—
0
12
17
139
1.22
0.29
1.4
1.4
5.82
5.79
mmol/l
0.05
17
132
8
109
0.73
0.29
13.1
12.2
825.63
873.06
nmol/l
—
8
103
55
497
1.11
0.28
1.8
2.3
130.74
126.69
g/l
0.54
42
347
19
227
0.84
0.28
1.5
1.5
56201.08
46557.99
e6/l
0.07
12
125
36
406
0.89
0.27
1.5
1.6
—
—
—
0
0
12
95
1.26
0.26
1.2
1.1
1781.83
1556.21
miu/ml
0.21
12
95
12
148
0.81
0.24
1.4
1.3
9.00
10.80
u/l
0.45
12
137
20
170
1.18
0.24
3.6
1.9
—
—
—
0
0
19
223
0.85
0.24
1.1
1.0
—
—
—
0
0
43
389
1.11
0.23
1.3
1.2
5.63
4.44
u/ml
0.13
16
111
48
437
1.10
0.23
1.3
2.2
0.82
0.81
nmol/l
0.04
37
364
17
143
1.19
0.23
1.1
1.6
—
—
—
0
0
11
88
1.25
0.22
1.3
1.6
—
—
—
0
0
57
618
0.92
0.22
3.9
3.5
15.51
29.67
u/ml
4.02
57
602
46
420
1.10
0.21
1.3
1.3
104.18
122.91
u/ml
0.50
11
85
10
124
0.81
0.21
3.0
2.5
44.20
44.27
%
—
5
68
19
163
1.17
0.21
1.1
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
2.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
5.1
—
365.20
—
0
10
0
13
0.00
0.21
0.0
2.8
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
254
2625
0.96
0.21
1.7
1.7
—
—
—
0
0
14
117
1.20
0.20
1.1
1.3
—
—
—
0
0
14
117
1.20
0.20
1.1
1.3
—
—
—
0
0
21
240
0.87
0.20
1.0
1.1
—
85.00
—
0
5
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
6
49
1.22
0.20
1.0
1.3
—
—
—
0
0
64
597
1.07
0.19
1.7
1.6
14264.06
10851.11
e6/l
0.24
48
443
107
1016
1.06
0.19
1.8
1.7
1.55
1.55
g/l
0.01
92
873
6
51
1.18
0.19
1.0
1.1
—
—
—
0
0
25
222
1.13
0.19
1.2
1.4
37.95
32.88
%
0.29
14
135
472
4621
1.03
0.19
3.8
3.4
187.33
336.70
ng/l
0.54
328
3430
52
559
0.93
0.18
1.3
1.6
—
—
—
0
0
141
1469
0.96
0.18
1.7
1.8
—
—
—
0
0
69
649
1.06
0.17
1.8
1.4
—
—
—
0
0
7
62
1.13
0.17
1.1
1.0
—
—
—
0
0
7
63
1.11
0.17
1.0
1.3
—
—
—
0
0
7
63
1.11
0.17
1.1
1.1
—
—
—
0
0
23
257
0.89
0.17
1.3
1.3
—
—
—
0
0
23
257
0.89
0.17
1.3
1.3
—
—
—
0
0
23
256
0.90
0.16
1.4
1.5
6041.24
2324.36
e6/l
0.34
17
182
13
111
1.17
0.15
1.2
1.2
—
—
—
0
0
8
73
1.10
0.15
1.0
1.0
—
—
—
0
0
112
1168
0.96
0.15
6.4
9.0
24.58
24.43
mmol/l
0.23
105
1146
61
575
1.06
0.15
3.3
3.2
1.60
1.50
mg/l
0.36
51
535
9
81
1.11
0.15
1.1
1.1
—
—
—
0
0
13
150
0.87
0.14
1.1
1.1
—
—
—
0
0
46
431
1.07
0.14
3.0
3.1
0.83
0.81
nmol/l
0.11
34
335
16
141
1.14
0.14
1.0
1.0
—
—
—
0
0
21
232
0.90
0.13
1.4
1.6
—
—
—
0
0
38
355
1.07
0.12
1.7
1.5
—
—
—
0
0
126
1302
0.97
0.12
1.5
1.4
—
—
—
0
0
16
179
0.89
0.12
1.6
1.4
291.63
328.55
u/l
0.17
16
174
11
95
1.16
0.11
3.7
4.9
—
—
—
0
0
32
298
1.07
0.11
1.0
1.1
0.90
4.42
u/ml
2.20
11
113
29
269
1.08
0.11
1.0
1.0
0.03
0.31
u/ml
—
6
77
12
105
1.14
0.11
1.2
1.1
—
—
—
0
0
65
679
0.96
0.11
1.9
1.6
—
—
—
0
0
11
125
0.88
0.10
1.0
1.1
—
—
—
0
0
14
125
1.12
0.10
1.1
1.3
120.86
135.67
nmol/l
0.61
14
125
14
125
1.12
0.10
1.0
1.1
—
—
—
0
0
5
45
1.11
0.09
1.0
1.2
—
—
—
0
0
74
768
0.96
0.09
2.4
2.7
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
75
724
1.04
0.09
2.9
2.8
0.33
0.37
u/ml
0.75
49
403
119
1159
1.03
0.09
1.6
1.7
—
—
—
0
0
51
531
0.96
0.08
1.5
1.4
—
—
—
0
0
6
72
0.83
0.07
1.3
1.2
—
—
—
0
0
51
530
0.96
0.07
1.5
1.4
—
—
—
0
0
51
530
0.96
0.07
1.5
1.4
—
—
—
0
0
8
77
1.04
0.07
1.0
1.3
—
—
—
0
0
8
77
1.04
0.07
1.4
1.5
7.66
8.95
ug/l
—
8
77
8
78
1.03
0.07
1.0
1.1
—
—
—
0
0
51
529
0.96
0.07
1.5
1.4
—
—
—
0
0
55
531
1.04
0.07
1.3
1.4
8.32
30.30
e6/l
1.46
44
395
9
101
0.89
0.06
1.2
1.1
—
—
—
0
0
55
532
1.03
0.06
1.4
1.5
1016.52
1311.07
e6/l
0.16
48
420
190
1928
0.98
0.06
3.2
2.7
198.20
173.35
ng/l
0.37
172
1751
96
942
1.02
0.05
3.2
3.4
200.99
2051.73
u/ml
1.00
76
798
13
140
0.93
0.04
1.3
1.5
9.77
12.69
u/l
1.33
13
134
28
269
1.04
0.04
1.1
1.5
1.87
4.03
ug/l
1.31
22
226
22
210
1.05
0.03
1.0
1.1
—
—
—
0
0
25
260
0.96
0.03
1.4
1.2
—
—
—
0
0
29
281
1.03
0.02
1.1
1.1
—
—
—
0
0
25
242
1.03
0.02
1.5
1.3
14166.83
58239.66
e6/l
0.70
18
167
10
93
1.08
0.02
1.7
1.2
—
—
—
0
0
31
302
1.03
0.02
1.1
1.4
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
14
133
1.05
0.01
1.0
1.1
—
—
—
0
0
35
357
0.98
0.01
1.1
1.4
—
—
—
0
0
13
124
1.05
0.00
1.5
1.5
—
—
—
0
0
13
124
1.05
0.00
1.1
1.6
—
—
—
0
0
30
306
0.98
0.00
1.2
1.1
—
—
—
0
0
13
125
1.04
0.00
1.1
1.7
—
—
—
0
0
13
134
0.97
0.00
1.0
1.0
1.27
1.05
u/l
—
6
72
263
2625
1.00
0.00
1.6
1.7
1.42
1.43
%
0.21
232
2303
33
326
1.01
0.00
1.0
1.0
1.25
2.83
u/ml
1.56
13
142
14
138
1.01
0.00
1.1
1.1
—
—
—
0
0
17
168
1.01
0.00
1.0
1.0
328.08
351.04
ng/l
0.21
12
114
17
172
0.99
0.00
1.0
1.0
47.14
47.66
ng/l
0.02
12
116
42
417
1.01
0.00
1.1
1.4
—
—
—
0
0
118
1177
1.00
0.00
1.3
1.4
—
—
—
0
0
8
87
0.92
0.00
1.0
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
3.9
—
—
—
0
0
5
59
0.85
-0.00
1.0
1.1
—
—
—
0
0
5
56
0.89
-0.00
1.4
1.3
—
—
—
0
0
17
170
1.00
-0.00
1.0
1.0
693.58
733.38
ng/l
0.14
12
112
0
5
0.00
-0.00
0.0
1.2
—
1.26
—
0
5
0
5
0.00
-0.00
0.0
1.6
—
32.40
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint E4_GOITRENOD and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_GOITRENOD | 0.933 [0.84, 1.03] | 0.168 |
| Birth year | 0.994 [0.99, 1.0] | 0.161 |
During the follow-up period (1.1.1998 — 31.12.2019), 978 out of 10026 females with E4_GOITRENOD died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_GOITRENOD | 0.863 [0.76, 0.98] | 0.019 |
| Birth year | 0.993 [0.98, 1.0] | 0.145 |
During the follow-up period (1.1.1998 — 31.12.2019), 395 out of 2426 males with E4_GOITRENOD died.
Mortality risk
Mortality risk for people of age
years, who have E4_GOITRENOD.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.064% | 0.205% |
| 5 | 0.56% | 1.157% |
| 10 | 1.27% | 3.068% |
| 15 | 2.514% | 5.741% |
| 20 | 4.303% | 10.132% |
Relationships between endpoints
↥Index endpoint: E4_GOITRENOD – Nontoxic single thyroid nodule
GWS hits: 5
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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