Other specified and unspecified disorders of conjunctiva

H7_CONJUNAS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H11.8, H11.9
  • Hospital discharge: ICD-9 372[8-9]
  • Cause of death: ICD-10 H11.8, H11.9
  • Cause of death: ICD-9 372[8-9]

2 out of 7 registries used, show all original rules.

370

4. Check minimum number of events

None

370

5. Include endpoints

None

370

6. Filter based on genotype QC (FinnGen only)

363

Control definitions (FinnGen only)

Control exclude
H7_CONJUNCTIVA

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2409 1232 1163
Only index persons 2216 1153 1063
Unadjusted period prevalence (%)
Whole population 0.03 0.04 0.03
Only index persons 0.04 0.04 0.04
Median age at first event (years)
Whole population 49.21 51.60 46.86
Only index persons 50.48 52.87 47.88

-FinnGen-

Key figures

All Female Male
Number of individuals 363 206 157
Unadjusted period prevalence (%) 0.07 0.07 0.07
Median age at first event (years) 58.15 56.88 59.80

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
370
Matched controls
3700
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H11.8
ICD-10 Finland
Other specified disorders of conjunctiva
+∞
234.0
199
*
H11.9
ICD-10 Finland
Disorder of conjunctiva, unspecified
2590.9
172.0
153
*
CFA20
NOMESCO Finland
Biopsy of conjunctiva
255.3
45.0
45
*
CFC00
NOMESCO Finland
Excision of lesion of conjunctiva
174.5
44.9
46
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
3.2
27.2
199
982
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
7.3
27.0
42
64
S01GX01
ATC
cromoglicic acid; ophthalmic
3.9
24.7
88
275
D31.0
ICD-10 Finland
Benign neoplasm: Conjunctiva
52.2
24.7
29
6
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
3.1
24.1
164
764
H11.4
ICD-10 Finland
Other conjunctival vascular disorders and cysts
+∞
23.2
22
*
H04.10
ICD-10 Finland
Dry eye syndrome
4.0
20.5
65
186
CD2S4
NOMESCO Finland
Photography of eye
70.2
17.9
20
*
WX100
NOMESCO Finland
Conjunctival surface anesthesia
3.3
15.4
65
223
CF2S4
NOMESCO Finland
Photography of conjunctiva
+∞
14.7
14
*
3728X
ICD-9 Finland
Disorders of conjunctiva, Other disorders of conjunctiva
+∞
14.7
14
*
H11.0
ICD-10 Finland
Pterygium
155.9
14.6
15
*
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
4.5
14.5
37
89
H11.1
ICD-10 Finland
Conjunctival degenerations and deposits
+∞
13.6
13
*
CBB30
NOMESCO Finland
Excision of lesion of eyelid
5.8
12.8
24
44
XCK10
NOMESCO Finland
Photography of fundus of eye
3.1
11.7
52
183
H01.0
ICD-10 Finland
Blepharitis
3.6
10.3
35
104
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.4
9.8
81
392
H10.4
ICD-10 Finland
Chronic conjunctivitis
102.6
9.5
10
*
3401
FHL
Removal of local modification or taking a specimen in the operating room
+∞
9.4
9
*
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
4.2
9.2
25
63
S01XA18
ATC
ciclosporin; ophthalmic
37.7
9.1
11
*
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
2.8
8.9
47
182
L04AA06
ATC
mycophenolic acid; systemic
10.4
8.6
16
16
127
Kela drug reimbursment
Transplant complication
11.1
8.4
15
14
CFA12
NOMESCO Finland
Resection of conjunctiva
+∞
8.4
8
*
S01GX02
ATC
levocabastine; ophthalmic
4.2
8.2
22
55
WX110
NOMESCO Finland
Infiltration anesthesia
2.0
8.1
270
2123
F01
ICPC
Eye pain
4.6
8.0
19
43
F02
ICPC
Red eye
3.7
7.7
25
72
H15.1
ICD-10 Finland
Episcleritis
10.3
7.6
14
14
TPH04
NOMESCO Finland
Cathetrisation of vein
2.1
7.5
88
486
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
3.2
7.5
30
99
CBA10
NOMESCO Finland
Biopsy of eyelid
13.7
7.4
12
9
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
30.7
7.2
9
*
S01GX09
ATC
olopatadine; ophthalmic
8.2
7.2
15
19
H10.0
ICD-10 Finland
Mucopurulent conjunctivitis
3.3
7.0
27
87
H16.0
ICD-10 Finland
Corneal ulcer
3.2
6.9
27
88
H26.4
ICD-10 Finland
After-cataract
2.7
6.9
38
151
H57.1
ICD-10 Finland
Ocular pain
3.6
6.4
21
61
H02.0
ICD-10 Finland
Entropion and trichiasis of eyelid
6.1
6.4
16
27
H01.80
ICD-10 Finland
Prolonged inflammation in the edge of the eyelid
18.4
6.3
9
5
F29
ICPC
Eye symptom/complaint other
2.5
6.3
42
183
3729X
ICD-9 Finland
Disorders of conjunctiva, Unspecified disorder of conjunctiva
+∞
6.3
6
*
CGE55
NOMESCO Finland
Excision of pterygium with transplanation of conjunctiva
+∞
6.3
6
*
CFD10
NOMESCO Finland
Repair of conjunctiva
+∞
6.3
6
*
WX002
NOMESCO Finland
Sedation and analgesia
2.0
6.2
75
417
WX402
NOMESCO Finland
General anaesthesia
2.0
6.1
79
449

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
236
1715
2.04
9.65
11.2
9.1
3.93
4.06
e9/l
0.44
212
1511
207
1453
1.96
9.16
7.5
5.7
0.58
0.57
e9/l
0.20
182
1264
211
1494
1.96
9.07
7.6
5.7
1.86
1.94
e9/l
0.32
191
1332
207
1458
1.95
9.01
7.5
5.7
0.04
0.04
e9/l
0.34
181
1269
211
1496
1.96
9.01
7.9
6.0
0.18
0.18
e9/l
0.14
187
1323
199
1388
1.94
8.87
9.5
6.2
—
—
—
0
0
178
1214
1.90
8.33
7.5
4.5
35.87
35.74
g/l
0.11
162
1151
48
198
2.64
8.05
4.9
2.8
262.83
176.81
ng/l
0.47
48
181
184
1289
1.85
7.74
11.2
5.8
1.21
1.21
mmol/l
0.10
167
1189
96
549
2.01
7.43
5.3
3.7
827.45
297.55
ng/l
0.30
68
423
187
1330
1.82
7.37
7.6
5.8
0.58
0.66
%
1.40
173
1243
189
1350
1.82
7.33
13.0
11.7
1.14
1.24
inr
0.96
40
398
192
1379
1.82
7.30
8.8
6.0
8.62
8.61
%
0.01
179
1297
195
1418
1.79
7.02
8.3
5.8
27.80
27.99
%
0.08
183
1336
190
1373
1.79
6.97
8.5
5.7
2.78
2.73
%
0.10
177
1289
192
1397
1.78
6.84
8.3
5.6
57.20
57.03
%
0.07
180
1315
46
202
2.46
6.78
6.0
3.8
97.37
75.61
ng/l
0.50
38
179
343
3048
2.72
6.25
20.5
13.1
20.84
23.50
mg/l
0.90
267
2370
114
732
1.81
6.06
3.0
2.6
350.33
6395.18
umol/l
2.86
105
642
274
2254
1.83
6.04
5.0
3.7
14.82
14.77
pmol/l
0.15
248
2040
224
1749
1.71
5.83
8.3
4.6
6.57
6.58
mmol/l
0.02
209
1616
267
2200
1.77
5.61
4.9
3.8
11.08
11.91
mm/h
0.48
253
2034
186
1411
1.64
5.17
13.8
6.6
1.22
1.21
mmol/l
0.73
165
1200
272
2275
1.74
5.17
10.2
7.3
77.63
79.64
u/l
0.38
262
2144
314
2754
1.93
4.92
5.9
4.4
1.83
1.88
mu/l
0.35
287
2512
59
330
1.94
4.75
2.4
1.7
—
—
—
0
0
99
651
1.71
4.70
3.8
1.7
2.31
1.27
mg/l
0.38
76
502
110
745
1.68
4.68
7.3
6.7
—
—
—
0
0
137
983
1.63
4.64
5.1
3.2
2.36
2.35
mmol/l
0.33
120
880
22
81
2.82
4.60
1.9
2.2
10.30
13.09
mg/l
0.66
22
76
43
217
2.11
4.59
1.5
1.6
—
—
—
0
0
125
881
1.63
4.53
7.2
3.8
7.40
7.40
ph
0.13
19
171
200
1578
1.58
4.50
8.4
6.1
10.95
10.98
umol/l
0.02
192
1498
76
472
1.77
4.39
6.9
3.5
0.82
0.82
mmol/l
0.02
68
446
149
1110
1.57
4.23
2.4
1.9
93.62
93.79
pmol/l
0.01
74
557
12
25
4.92
4.22
1.1
1.4
—
—
—
0
0
115
807
1.62
4.19
3.9
2.8
—
—
—
0
0
31
142
2.29
4.18
21.2
11.1
—
—
—
0
0
113
793
1.61
4.11
4.0
3.0
1745.79
1115.41
ng/l
0.71
97
676
13
32
4.17
3.94
1.4
1.4
—
—
—
0
0
42
223
2.00
3.92
2.4
2.5
9.40
10.31
g/l
0.88
37
205
165
1274
1.53
3.91
3.3
2.6
137.01
116.31
ug/l
0.57
157
1176
12
28
4.39
3.85
2.2
2.9
—
—
—
0
0
248
2098
1.55
3.80
4.9
3.7
—
—
—
0
0
59
355
1.79
3.78
1.8
1.6
—
—
—
0
0
70
443
1.72
3.76
2.8
2.8
3.51
2.21
e6/l
0.47
39
236
120
870
1.56
3.75
3.0
2.0
215.14
288.02
u/l
0.33
109
821
20
79
2.62
3.69
2.2
3.1
—
—
—
0
0
16
56
2.94
3.67
2.1
1.4
114.00
99.45
u/ml
—
5
11
153
1178
1.51
3.60
2.4
2.0
—
—
—
0
0
61
376
1.75
3.60
3.8
2.1
22.96
23.22
%
0.04
47
327
113
816
1.55
3.57
3.9
2.9
0.33
0.49
e6/l
0.68
87
616
64
403
1.71
3.50
3.6
2.1
2.23
2.38
g/l
1.24
59
376
41
225
1.92
3.50
18.6
7.4
—
—
—
0
0
48
278
1.83
3.48
3.4
2.2
40.67
202.68
u/l
0.46
40
238
57
348
1.75
3.47
1.9
1.4
—
—
—
0
0
121
898
1.52
3.34
3.9
3.0
30.76
118.12
e6/l
0.63
97
689
344
3198
2.08
3.31
18.8
12.2
—
—
—
0
0
15
54
2.85
3.29
1.1
1.2
—
—
—
0
0
38
209
1.91
3.23
1.6
1.4
—
—
—
0
0
12
34
3.61
3.22
1.8
2.3
—
—
—
0
0
137
1052
1.48
3.18
4.4
3.5
38.34
77.91
e6/l
0.76
101
739
151
1183
1.47
3.16
2.6
2.3
78.03
77.26
nmol/l
0.12
134
1067
360
3418
2.97
3.16
30.4
19.2
40.27
40.42
%
0.19
333
3225
360
3419
2.96
3.13
28.9
19.2
244.28
248.65
e9/l
0.71
353
3337
77
524
1.59
3.11
2.7
2.8
2.45
2.45
mmol/l
0.07
66
464
64
417
1.65
3.08
3.1
2.1
—
—
—
0
0
360
3423
2.91
3.05
28.8
19.1
4.50
4.52
e12/l
0.30
353
3332
360
3423
2.91
3.05
28.8
19.1
6.59
6.64
e9/l
0.21
353
3331
16
63
2.61
3.00
2.1
1.4
—
—
—
0
0
94
676
1.52
2.97
3.6
3.4
—
—
—
0
0
26
131
2.06
2.83
8.4
3.4
24.06
24.42
mmol/l
0.27
26
131
73
502
1.57
2.81
1.8
1.7
991.55
1208.83
nmol/l
1.50
58
370
5
6
8.42
2.75
2.2
1.0
—
—
—
0
0
57
371
1.63
2.75
1.4
1.2
—
—
—
0
0
58
381
1.62
2.70
1.4
1.4
528.00
450.60
titre
—
10
83
238
2067
1.42
2.68
5.5
3.9
—
—
—
0
0
105
793
1.45
2.58
7.1
4.2
—
—
—
0
0
17
75
2.33
2.55
1.1
1.1
—
—
—
0
0
12
45
2.72
2.47
11.3
1.6
53.80
60.16
%
0.39
12
45
167
1380
1.38
2.44
4.2
2.5
—
—
—
0
0
5
8
6.32
2.38
1.2
1.1
—
—
—
0
0
43
271
1.66
2.36
1.4
1.4
—
—
—
0
0
91
681
1.45
2.33
1.9
1.5
23.98
20.75
nmol/l
0.64
81
571
80
584
1.47
2.32
4.0
2.7
591.97
554.97
mosm/kgh2o
0.69
66
505
55
372
1.56
2.28
1.5
2.3
102.43
127.27
ug/g
0.40
42
297
6
13
4.67
2.28
1.2
1.5
—
—
—
0
0
67
474
1.50
2.27
2.0
1.7
—
—
—
0
0
51
343
1.56
2.17
16.2
6.2
104.27
104.50
mmol/l
0.12
51
343
9
30
3.05
2.16
1.6
1.1
—
—
—
0
0
7
19
3.73
2.16
2.3
1.4
9.71
11.83
%
—
7
19
83
619
1.44
2.15
3.5
2.5
4.46
5.14
e6/l
0.26
74
563
17
82
2.12
2.10
1.2
1.4
286.00
320.89
ug/g
—
10
50
90
687
1.41
2.05
2.2
2.0
2.58
3.06
mg/l
1.82
79
595
20
104
1.98
2.04
1.6
2.3
624.74
4510.37
u/l
—
10
38
14
63
2.27
2.03
3.4
1.6
4.21
5.87
iu/l
—
7
19
8
26
3.12
2.02
2.6
2.9
—
—
—
0
0
19
98
1.99
1.99
1.2
1.2
—
—
—
0
0
7
21
3.38
1.97
1.7
2.8
596.57
606.57
u/ml
—
7
21
139
1146
1.34
1.96
4.6
3.5
54.62
61.37
ng/l
0.07
89
781
313
2917
1.47
1.96
4.9
4.3
6.01
5.92
mmol/l
0.59
286
2667
9
33
2.77
1.94
1.8
1.7
13.63
13.05
%
—
9
33
117
943
1.35
1.91
4.7
2.5
58.56
60.89
u/l
0.14
108
879
19
100
1.95
1.89
1.4
1.3
—
—
—
0
0
21
115
1.88
1.87
1.0
1.2
—
—
—
0
0
158
1335
1.32
1.86
10.4
9.1
0.00
0.00
e9/l
0.61
126
1102
48
331
1.52
1.84
15.3
8.1
0.88
1.20
mmol/l
0.23
43
267
320
3005
1.48
1.82
4.5
4.2
4.56
4.69
mmol/l
1.58
300
2793
9
35
2.61
1.81
1.1
1.1
—
—
—
0
0
319
2996
1.47
1.79
4.4
4.2
1.44
1.47
mmol/l
0.52
296
2775
34
219
1.61
1.75
4.4
4.0
0.69
0.52
%
0.36
13
73
230
2060
1.31
1.72
3.9
3.0
55.75
46.69
u/l
0.50
213
1931
308
2881
1.41
1.70
4.0
3.8
1.31
1.29
mmol/l
0.20
281
2662
324
3062
1.47
1.65
5.3
4.7
2.72
2.79
mmol/l
0.76
304
2833
76
586
1.37
1.63
2.2
1.8
—
—
—
0
0
5
14
3.60
1.62
1.6
1.2
27.00
29.21
umol/l
—
5
14
10
43
2.36
1.60
1.0
1.2
—
—
—
0
0
8
33
2.45
1.54
1.4
1.2
—
—
—
0
0
110
906
1.30
1.51
3.3
2.3
—
—
—
0
0
6
21
2.89
1.51
1.2
2.0
10.58
12.66
umol/l
—
6
21
47
338
1.45
1.49
1.8
1.6
—
—
—
0
0
34
229
1.53
1.48
1.1
1.1
—
—
—
0
0
37
255
1.50
1.45
9.9
3.2
1.89
2.12
mmol/l
0.16
32
200
108
892
1.30
1.45
4.1
2.9
6.94
7.60
mmol/l
1.20
92
763
5
16
3.15
1.44
1.0
1.1
—
—
—
0
0
94
1139
0.77
1.43
3.1
2.7
—
—
—
0
0
296
2774
1.34
1.42
6.4
5.3
39.85
39.60
mmol/mol
0.18
278
2596
23
142
1.66
1.42
2.0
2.2
—
—
—
0
0
5
17
2.97
1.36
1.0
1.2
—
—
—
0
0
32
217
1.52
1.36
3.1
2.5
58.46
66.43
e9/l
1.15
26
165
168
1477
1.25
1.34
4.0
3.4
0.00
0.00
estimate
0.50
28
311
13
69
1.92
1.30
1.2
1.1
—
—
—
0
0
5
18
2.80
1.29
1.0
1.1
—
—
—
0
0
11
55
2.03
1.28
12.6
2.5
—
—
—
0
0
19
115
1.69
1.27
1.1
1.1
—
—
—
0
0
35
246
1.47
1.27
4.7
4.0
1.00
1.06
%
0.07
13
91
102
853
1.27
1.23
5.1
3.6
4.27
10.17
mg/mmol
2.12
72
534
17
101
1.72
1.22
1.3
1.5
241.00
246.52
miu/ml
—
5
52
19
117
1.66
1.20
2.7
1.9
1.60
1.56
g/l
0.07
19
103
102
858
1.26
1.17
3.2
2.8
—
—
—
0
0
94
783
1.27
1.17
1.7
1.6
1.22
1.43
mmol/l
2.63
88
658
337
3245
1.43
1.17
14.2
9.8
26.31
26.74
u/l
0.19
331
3131
96
803
1.26
1.15
4.3
3.1
581.36
385.81
mg/l
0.13
70
525
5
20
2.52
1.15
3.0
3.3
—
—
—
0
0
38
277
1.41
1.15
1.6
1.4
—
—
—
0
0
7
30
2.36
1.13
1.6
1.0
—
—
—
0
0
18
112
1.64
1.11
1.3
1.7
—
—
—
0
0
167
1491
1.22
1.10
4.0
3.4
0.00
0.00
estimate
-0.00
26
280
5
21
2.40
1.09
1.2
1.2
—
—
—
0
0
165
1476
1.21
1.05
5.2
4.5
0.00
0.00
estimate
0.50
28
291
28
198
1.45
1.01
1.1
1.2
127.44
134.01
iu/ml
0.04
11
82
99
844
1.24
1.01
1.6
1.5
—
—
—
0
0
26
182
1.46
0.99
3.2
2.6
3.17
5.95
e9/l
1.20
19
150
5
23
2.19
0.98
1.2
1.0
—
—
—
0
0
30
217
1.42
0.97
4.1
4.3
0.75
0.17
%
—
8
66
0
31
0.00
0.97
0.0
1.5
—
—
—
0
0
7
37
1.91
0.94
1.4
1.4
—
—
—
0
0
28
203
1.41
0.90
5.5
6.7
—
—
—
0
0
20
136
1.50
0.88
8.0
2.2
1.13
1.28
%
0.23
20
136
77
648
1.24
0.88
4.1
3.6
1.01
1.02
kg/l
—
7
74
11
65
1.71
0.83
2.5
2.7
1.42
2.43
mmol/l
—
6
40
39
304
1.32
0.82
1.7
1.7
—
—
—
0
0
11
66
1.69
0.79
1.5
1.9
—
—
—
0
0
9
54
1.68
0.75
1.2
1.3
—
—
—
0
0
63
530
1.23
0.73
2.1
2.8
0.57
0.77
ug/l
2.37
42
329
17
117
1.47
0.73
3.3
2.0
7.24
3.67
ug/l
0.32
17
109
19
134
1.44
0.73
8.2
2.2
0.51
0.66
%
2.19
19
134
25
187
1.36
0.70
1.3
1.2
—
—
—
0
0
31
241
1.31
0.68
5.1
3.1
—
—
—
0
0
67
572
1.21
0.68
1.5
1.8
213793510.84
437.39
pmol/l
0.49
58
477
30
233
1.31
0.67
4.2
4.2
0.00
0.15
%
—
8
78
13
87
1.51
0.64
11.2
2.1
1589.00
770.93
ug/l
0.24
13
81
5
29
1.73
0.64
1.2
1.1
—
—
—
0
0
31
246
1.28
0.60
5.7
4.1
—
—
—
0
0
0
20
0.00
0.60
0.0
2.0
—
3.43
—
0
20
46
386
1.22
0.57
1.2
1.2
—
—
—
0
0
6
36
1.68
0.57
4.5
4.2
375.17
356.13
umol/l
—
6
31
13
90
1.46
0.56
1.5
1.6
—
—
—
0
0
38
313
1.24
0.56
2.7
4.0
19.03
20.92
ug/l
0.03
27
263
6
37
1.63
0.56
1.0
1.4
—
—
nmol/l
—
0
0
6
37
1.63
0.56
1.0
1.1
—
—
—
0
0
100
903
1.15
0.53
3.9
4.6
1.46
2.30
ug/l
1.61
93
814
9
63
1.44
0.52
2.8
1.7
—
—
—
0
0
9
64
1.42
0.52
1.6
1.8
—
—
—
0
0
6
40
1.51
0.52
1.0
1.3
—
—
—
0
0
75
838
0.87
0.49
4.2
3.0
—
—
—
0
0
7
47
1.50
0.48
1.1
1.3
214.31
14.24
u/l
—
7
40
10
68
1.48
0.47
3.1
2.2
—
—
—
0
0
27
330
0.80
0.47
1.1
1.4
—
—
—
0
0
7
49
1.44
0.46
1.0
1.0
—
—
—
0
0
10
69
1.46
0.44
2.3
2.0
123.60
131.62
g/l
—
5
48
17
218
0.77
0.44
1.4
1.4
—
—
—
0
0
5
33
1.52
0.41
1.2
1.5
71.65
16.49
ug/l
—
5
33
5
33
1.52
0.41
1.2
1.8
87.78
89.27
%
—
5
33
5
33
1.52
0.41
1.2
1.2
—
—
—
0
0
8
59
1.36
0.41
1.0
1.1
—
—
—
0
0
8
59
1.36
0.41
2.4
2.0
6.62
5.08
mmol/24h
—
8
51
0
17
0.00
0.40
0.0
1.7
—
—
—
0
0
0
17
0.00
0.40
0.0
1.6
—
—
—
0
0
5
34
1.48
0.40
1.6
2.5
—
—
—
0
0
10
137
0.72
0.40
9.6
3.8
—
—
—
0
0
5
35
1.43
0.39
1.0
1.4
0.19
0.42
nmol/l
—
5
28
9
66
1.37
0.38
1.0
1.2
—
—
—
0
0
5
37
1.36
0.37
3.8
1.4
—
—
—
0
0
9
70
1.29
0.37
2.4
4.2
—
—
—
0
0
10
135
0.73
0.37
1.7
1.7
—
—
—
0
0
6
42
1.44
0.35
1.2
1.1
—
—
—
0
0
6
42
1.44
0.35
1.2
1.1
—
—
—
0
0
17
137
1.25
0.32
3.2
3.2
—
—
—
0
0
14
110
1.28
0.32
5.4
3.4
0.19
0.22
g/l
—
7
44
13
102
1.28
0.30
1.8
2.9
—
—
—
0
0
13
105
1.25
0.25
7.0
8.8
—
—
—
0
0
76
813
0.92
0.25
3.3
3.7
—
—
—
0
0
52
476
1.11
0.24
1.3
1.3
9.37
8.06
u/ml
0.06
23
189
5
40
1.25
0.22
4.8
3.3
—
—
—
0
0
5
42
1.19
0.21
1.4
3.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
1.88
—
0
5
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
2.0
—
43.67
—
0
6
0
10
0.00
0.21
0.0
1.5
—
135.57
—
0
10
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
2.4
—
33400.50
—
0
10
73
685
1.08
0.21
1.4
1.2
0.59
1.08
u/ml
1.71
12
207
0
14
0.00
0.20
0.0
1.5
—
—
—
0
0
7
63
1.11
0.17
10.7
1.3
0.95
0.97
nmol/l
—
7
54
54
507
1.08
0.16
1.4
1.3
10.84
32.81
iu/ml
4.14
19
165
21
187
1.13
0.16
1.3
1.2
—
—
—
0
0
65
617
1.06
0.15
1.5
1.4
2.27
2.36
g/l
0.08
36
391
33
306
1.09
0.13
1.4
1.4
—
—
—
0
0
12
105
1.15
0.11
2.4
1.6
—
—
—
0
0
20
183
1.10
0.10
1.7
2.3
—
—
—
0
0
6
56
1.07
0.08
8.5
3.4
3.39
4.65
e9/l
—
6
56
28
270
1.04
0.03
5.8
3.4
—
—
—
0
0
81
820
0.98
0.02
5.3
3.6
0.00
0.01
estimate
0.80
27
288
13
137
0.95
0.01
2.3
1.6
—
—
—
0
0
13
137
0.95
0.01
2.3
1.6
—
—
—
0
0
13
137
0.95
0.01
2.3
1.6
—
—
—
0
0
13
137
0.95
0.01
2.3
1.6
—
—
—
0
0
32
326
0.98
0.00
1.3
1.3
—
—
—
0
0
12
118
1.02
0.00
4.7
5.2
—
—
—
0
0
20
199
1.01
0.00
1.6
2.3
—
—
—
0
0
10
95
1.05
0.00
2.7
1.9
—
—
—
0
0
12
125
0.96
0.00
2.4
1.7
—
—
—
0
0
13
134
0.97
0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
76.88
—
0
5
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
7
73
0.96
0.00
1.7
1.5
—
—
—
0
0
0
8
0.00
0.00
0.0
2.1
—
1.17
—
0
8
0
5
0.00
0.00
0.0
1.0
—
15.12
—
0
5
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
7
70
1.00
-0.00
1.7
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
70
1.00
-0.00
1.6
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
8
84
0.95
-0.00
9.5
3.3
1.91
1.40
mg/l
—
8
74
0
6
0.00
-0.00
0.0
1.5
—
40.00
—
0
6
0
6
0.00
-0.00
0.0
1.5
—
20.13
—
0
6
6
60
1.00
-0.00
1.2
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
54
0.92
-0.00
3.8
2.3
—
—
—
0
0
6
65
0.92
-0.00
1.5
1.5
—
—
—
0
0
6
60
1.00
-0.00
10.0
3.8
56.50
60.03
%
—
6
60
5
50
1.00
-0.00
9.6
2.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint H7_CONJUNAS and mortality.

Females

Parameter HR [95% CI] p-value
H7_CONJUNAS 0.931 [0.7, 1.24] 0.623
Birth year 0.999 [0.99, 1.01] 0.831

During the follow-up period (1.1.1998 — 31.12.2019), 71 out of 895 females with H7_CONJUNAS died.

Males

Parameter HR [95% CI] p-value
H7_CONJUNAS 1.148 [0.85, 1.55] 0.366
Birth year 0.983 [0.97, 0.99] < 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 107 out of 871 males with H7_CONJUNAS died.

Mortality risk

Mortality risk for people of age

years, who have H7_CONJUNAS.

N-year risk Females Males
1 0.09% 0.194%
5 0.57% 1.137%
10 1.522% 2.871%
15 3.012% 5.649%
20 5.316% 9.392%

Relationships between endpoints

Index endpoint: H7_CONJUNAS – Other specified and unspecified disorders of conjunctiva

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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