No definition available.
Other specified and unspecified disorders of conjunctiva
DOID EFO Endpoint Browser PheWeb
H7_CONJUNAS
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
329 |
4. Check minimum number of eventsNone |
329 |
5. Include endpointsNone |
329 |
6. Filter based on genotype QC (FinnGen only) |
329 |
Control definitions (FinnGen only)
- Control exclude
- H7_CONJUNCTIVA
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Other specified and unspecified disorders of conjunctiva
based on the number of shared cases.
Similar with more cases:
- Other disorders of conjunctiva
- Disorders of conjunctiva
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2409 | 1232 | 1163 |
| Only index persons | 2216 | 1153 | 1063 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.03 | 0.04 | 0.03 |
| Only index persons | 0.04 | 0.04 | 0.04 |
| Median age at first event (years) | |||
| Whole population | 49.21 | 51.60 | 46.86 |
| Only index persons | 50.48 | 52.87 | 47.88 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 329 | 184 | 145 |
| Unadjusted period prevalence (%) | 0.06 | 0.06 | 0.06 |
| Median age at first event (years) | 58.44 | 56.88 | 60.41 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 281
- Matched controls
- 2811
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H11.8
ICD-10 Finland
Other specified disorders of conjunctiva
2644.5
156.8
137
*
H11.9
ICD-10 Finland
Disorder of conjunctiva, unspecified
+∞
144.6
126
*
CFC00
NOMESCO Finland
Excision of lesion of conjunctiva
433.3
39.1
38
*
CFA20
NOMESCO Finland
Biopsy of conjunctiva
393.8
35.8
35
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
3.2
18.8
144
692
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
3.0
15.5
123
585
D31.0
ICD-10 Finland
Benign neoplasm: Conjunctiva
21.6
15.4
22
11
H11.4
ICD-10 Finland
Other conjunctival vascular disorders and cysts
+∞
13.6
13
*
3728X
ICD-9 Finland
Disorders of conjunctiva, Other disorders of conjunctiva
+∞
13.6
13
*
S01GX01
ATC
cromoglicic acid; ophthalmic
3.8
13.6
62
194
CD2S4
NOMESCO Finland
Photography of eye
42.3
13.3
16
*
H04.10
ICD-10 Finland
Dry eye syndrome
4.6
12.7
45
111
CF2S4
NOMESCO Finland
Photography of conjunctiva
+∞
12.6
12
*
WX100
NOMESCO Finland
Conjunctival surface anesthesia
4.0
11.6
48
137
CBA10
NOMESCO Finland
Biopsy of eyelid
62.4
10.7
12
*
H11.0
ICD-10 Finland
Pterygium
+∞
10.5
10
*
3401
FHL
Removal of local modification or taking a specimen in the operating room
+∞
9.4
9
*
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
5.9
9.2
25
46
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
5.2
8.6
26
54
S01XA18
ATC
ciclosporin; ophthalmic
92.7
8.5
9
*
F02
ICPC
Red eye
6.2
7.8
20
34
H11.1
ICD-10 Finland
Conjunctival degenerations and deposits
+∞
7.3
7
*
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
3.5
7.3
33
102
H01.0
ICD-10 Finland
Blepharitis
4.8
7.3
23
51
Z96.1
ICD-10 Finland
Presence of intraocular lens
2.8
6.4
41
163
CFA12
NOMESCO Finland
Resection of conjunctiva
+∞
6.3
6
*
Mortality – FinRegistry
↥Association
Association between endpoint H7_CONJUNAS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_CONJUNAS | 0.931 [0.7, 1.24] | 0.623 |
| Birth year | 0.999 [0.99, 1.01] | 0.831 |
During the follow-up period (1.1.1998 — 31.12.2019), 71 out of 895 females with H7_CONJUNAS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_CONJUNAS | 1.148 [0.85, 1.55] | 0.366 |
| Birth year | 0.983 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 107 out of 871 males with H7_CONJUNAS died.
Mortality risk
Mortality risk for people of age
years, who have H7_CONJUNAS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.09% | 0.194% |
| 5 | 0.57% | 1.137% |
| 10 | 1.522% | 2.871% |
| 15 | 3.012% | 5.649% |
| 20 | 5.316% | 9.392% |
Relationships between endpoints
↥Index endpoint: H7_CONJUNAS – Other specified and unspecified disorders of conjunctiva
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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