Other specified and unspecified disorders of conjunctiva

H7_CONJUNAS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H11.8, H11.9
  • Hospital discharge: ICD-9 372[8-9]
  • Cause of death: ICD-10 H11.8, H11.9
  • Cause of death: ICD-9 372[8-9]

2 out of 7 registries used, show all original rules.

329

4. Check minimum number of events

None

329

5. Include endpoints

None

329

6. Filter based on genotype QC (FinnGen only)

329

Control definitions (FinnGen only)

Control exclude
H7_CONJUNCTIVA

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2409 1232 1163
Only index persons 2216 1153 1063
Unadjusted period prevalence (%)
Whole population 0.03 0.04 0.03
Only index persons 0.04 0.04 0.04
Median age at first event (years)
Whole population 49.21 51.60 46.86
Only index persons 50.48 52.87 47.88

-FinnGen-

Key figures

All Female Male
Number of individuals 329 184 145
Unadjusted period prevalence (%) 0.06 0.06 0.06
Median age at first event (years) 58.44 56.88 60.41

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
281
Matched controls
2811
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H11.8
ICD-10 Finland
Other specified disorders of conjunctiva
2644.5
156.8
137
*
H11.9
ICD-10 Finland
Disorder of conjunctiva, unspecified
+∞
144.6
126
*
CFC00
NOMESCO Finland
Excision of lesion of conjunctiva
433.3
39.1
38
*
CFA20
NOMESCO Finland
Biopsy of conjunctiva
393.8
35.8
35
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
3.2
18.8
144
692
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
3.0
15.5
123
585
D31.0
ICD-10 Finland
Benign neoplasm: Conjunctiva
21.6
15.4
22
11
3728X
ICD-9 Finland
Disorders of conjunctiva, Other disorders of conjunctiva
+∞
13.6
13
*
H11.4
ICD-10 Finland
Other conjunctival vascular disorders and cysts
+∞
13.6
13
*
S01GX01
ATC
cromoglicic acid; ophthalmic
3.8
13.6
62
194
CD2S4
NOMESCO Finland
Photography of eye
42.3
13.3
16
*
H04.10
ICD-10 Finland
Dry eye syndrome
4.6
12.7
45
111
CF2S4
NOMESCO Finland
Photography of conjunctiva
+∞
12.6
12
*
WX100
NOMESCO Finland
Conjunctival surface anesthesia
4.0
11.6
48
137
CBA10
NOMESCO Finland
Biopsy of eyelid
62.4
10.7
12
*
H11.0
ICD-10 Finland
Pterygium
+∞
10.5
10
*
3401
FHL
Removal of local modification or taking a specimen in the operating room
+∞
9.4
9
*
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
5.9
9.2
25
46
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
5.2
8.6
26
54
S01XA18
ATC
ciclosporin; ophthalmic
92.7
8.5
9
*
F02
ICPC
Red eye
6.2
7.8
20
34
H11.1
ICD-10 Finland
Conjunctival degenerations and deposits
+∞
7.3
7
*
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
3.5
7.3
33
102
H01.0
ICD-10 Finland
Blepharitis
4.8
7.3
23
51
Z96.1
ICD-10 Finland
Presence of intraocular lens
2.8
6.4
41
163
CFA12
NOMESCO Finland
Resection of conjunctiva
+∞
6.3
6
*

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
136
854
2.01
8.44
8.2
5.6
—
—
—
0
0
207
1534
1.94
7.62
10.9
9.4
4.0
4.1
e9/l
0.16
187
1349
43
183
2.55
6.81
5.8
3.8
99.5
76.3
ng/l
0.49
35
163
184
1345
1.84
6.72
7.4
5.8
1.9
1.9
e9/l
0.31
166
1190
180
1307
1.83
6.72
7.3
5.7
0.6
0.6
e9/l
0.18
158
1130
184
1349
1.83
6.62
7.7
6.0
0.2
0.2
e9/l
0.27
163
1192
156
1088
1.83
6.61
7.7
4.5
35.5
35.6
g/l
0.06
140
1028
180
1313
1.82
6.56
7.4
5.7
0.0
0.0
e9/l
0.13
157
1137
42
186
2.44
6.12
5.3
2.9
294.0
181.6
ng/l
0.57
42
170
162
1167
1.76
5.97
11.6
5.9
1.2
1.2
mmol/l
0.02
145
1074
84
500
1.91
5.76
5.4
3.7
958.2
246.2
ng/l
0.36
58
392
203
1570
1.77
5.75
8.6
4.7
6.6
6.6
mmol/l
0.06
190
1453
57
300
2.09
5.51
2.4
1.7
—
—
—
0
0
103
667
1.79
5.36
3.0
2.6
347.1
5510.8
umol/l
2.46
94
577
162
1194
1.70
5.30
7.5
5.9
0.6
0.7
%
1.37
148
1114
166
1240
1.68
5.11
8.6
6.0
8.6
8.6
%
0.00
153
1166
169
1274
1.67
4.98
8.1
5.8
28.0
27.9
%
0.04
155
1194
12
28
4.41
4.86
1.4
1.4
—
—
—
0
0
145
1057
1.66
4.82
10.6
7.9
1.2
1.2
inr
0.54
33
319
164
1234
1.66
4.81
8.4
5.7
2.7
2.7
%
0.08
151
1153
302
2707
2.41
4.80
21.2
13.5
21.1
23.9
mg/l
0.88
234
2107
166
1259
1.64
4.68
8.3
5.7
57.4
57.1
%
0.11
153
1185
242
2035
1.72
4.44
10.1
7.4
77.9
80.0
u/l
0.37
233
1915
239
2006
1.70
4.38
5.2
3.7
14.8
14.8
pmol/l
0.17
214
1806
10
23
4.45
4.11
1.1
1.5
—
—
—
0
0
86
569
1.69
4.01
4.0
1.7
2.6
1.3
mg/l
0.41
67
440
164
1272
1.58
4.01
14.4
6.6
1.2
1.2
mmol/l
0.54
147
1077
38
194
2.08
3.97
1.6
1.4
—
—
—
0
0
121
880
1.59
3.86
5.0
3.3
2.4
2.4
mmol/l
0.14
104
779
233
1974
1.62
3.80
4.9
3.8
11.0
12.1
mm/h
0.58
220
1816
54
317
1.84
3.79
1.9
1.4
—
—
—
0
0
149
1143
1.55
3.75
3.3
2.6
139.3
118.3
ug/l
0.51
141
1051
135
1016
1.56
3.68
2.3
1.9
90.3
93.4
pmol/l
0.28
66
507
276
2457
1.77
3.56
6.0
4.4
1.9
1.9
mu/l
0.05
249
2230
10
26
3.94
3.54
2.2
2.8
—
—
—
0
0
139
1060
1.54
3.54
2.4
2.0
—
—
—
0
0
176
1415
1.52
3.49
8.6
6.2
11.2
11.1
umol/l
0.04
168
1344
96
679
1.58
3.38
7.3
6.9
—
—
—
0
0
36
192
1.98
3.36
1.5
1.6
—
—
—
0
0
59
369
1.73
3.35
3.2
2.0
—
—
—
0
0
222
1891
1.53
3.25
4.9
3.7
—
—
—
0
0
10
28
3.65
3.22
1.8
2.3
—
—
—
0
0
10
28
3.65
3.22
1.4
1.3
—
—
—
0
0
19
80
2.46
3.12
6.4
11.4
1.1
1.4
mmol/l
0.73
19
68
15
56
2.76
3.10
7.0
13.8
104.1
104.8
mmol/l
0.17
15
49
15
56
2.76
3.10
7.0
13.8
11.0
11.4
mmol/l
0.17
15
49
18
75
2.48
3.02
2.6
3.1
—
—
—
0
0
14
51
2.82
3.02
2.1
1.4
114.0
99.5
u/ml
—
5
11
51
315
1.73
3.02
1.8
1.6
—
—
—
0
0
106
784
1.52
3.02
3.1
2.0
213.2
299.2
u/l
0.35
98
738
37
210
1.86
2.89
19.2
7.1
—
—
—
0
0
11
37
3.04
2.72
1.5
1.4
—
—
—
0
0
11
37
3.04
2.72
1.5
1.4
—
—
—
0
0
11
37
3.04
2.72
1.5
1.4
—
—
—
0
0
11
37
3.04
2.72
1.5
1.4
—
—
—
0
0
29
155
1.96
2.71
17.6
4.7
25.1
24.9
mmol/l
0.11
29
155
12
43
2.86
2.67
11.3
1.6
53.8
59.3
%
0.33
12
43
319
3032
2.71
2.66
29.2
19.6
242.0
248.1
e9/l
1.04
312
2957
98
730
1.49
2.65
4.0
2.8
—
—
—
0
0
319
3035
2.68
2.59
29.1
19.6
4.5
4.5
e12/l
0.32
312
2951
319
3036
2.67
2.57
29.2
19.6
6.6
6.6
e9/l
0.10
312
2950
56
371
1.61
2.55
3.6
2.1
2.2
2.4
g/l
1.05
51
347
304
2843
1.91
2.55
19.7
12.4
—
—
—
0
0
68
472
1.56
2.55
1.8
1.7
986.2
1209.8
nmol/l
1.47
54
351
53
347
1.63
2.53
3.7
2.2
23.9
23.6
%
0.05
42
306
129
1024
1.43
2.48
4.4
3.6
58.0
66.0
ng/l
0.08
84
708
14
57
2.52
2.48
2.1
1.5
—
—
—
0
0
52
341
1.62
2.47
1.4
1.4
444.4
444.8
titre
—
9
75
120
942
1.43
2.45
4.5
3.6
18.5
79.8
e6/l
2.21
92
661
83
608
1.49
2.42
3.5
3.4
—
—
—
0
0
42
262
1.69
2.41
3.7
2.2
42.6
213.8
u/l
0.46
35
223
5
8
6.32
2.38
1.2
1.1
—
—
—
0
0
104
799
1.44
2.37
7.4
3.9
7.4
7.4
ph
0.05
17
151
25
135
1.92
2.29
24.4
11.4
—
—
—
0
0
7
18
3.95
2.26
2.3
1.4
9.7
11.3
%
—
7
18
50
333
1.59
2.24
1.4
1.2
—
—
—
0
0
104
807
1.42
2.23
4.1
3.1
17.3
127.4
e6/l
0.76
88
617
13
54
2.47
2.22
3.6
1.6
4.5
6.4
iu/l
—
6
16
94
717
1.44
2.21
7.3
4.3
—
—
—
0
0
12
48
2.56
2.21
1.2
1.2
—
—
—
0
0
96
737
1.43
2.18
4.1
2.9
0.4
0.5
e6/l
0.42
77
553
61
429
1.52
2.15
8.2
3.5
0.8
0.8
mmol/l
0.27
55
404
8
25
3.25
2.11
3.0
2.7
—
—
—
0
0
17
82
2.13
2.11
1.6
2.2
620.0
5509.8
u/l
—
9
29
65
466
1.49
2.10
2.6
3.0
2.5
2.5
mmol/l
0.02
54
411
75
556
1.45
2.05
3.5
2.5
3.8
5.1
e6/l
0.77
66
496
210
1849
1.38
2.04
5.6
3.9
—
—
—
0
0
148
1243
1.35
1.91
7.1
4.0
—
—
—
0
0
70
523
1.43
1.83
3.9
2.6
577.4
563.4
mosm/kgh2o
0.21
56
445
105
841
1.37
1.83
4.9
2.6
58.5
56.4
u/l
0.18
96
780
81
624
1.40
1.78
2.1
2.0
2.6
3.1
mg/l
1.85
70
542
80
615
1.40
1.78
6.7
4.8
—
—
—
0
0
47
326
1.52
1.78
1.5
2.2
109.0
131.3
ug/g
0.29
35
260
32
204
1.63
1.73
1.2
1.2
—
—
—
0
0
80
618
1.39
1.73
1.8
1.5
24.3
20.9
nmol/l
0.59
70
515
5
13
3.89
1.72
1.0
1.1
—
—
—
0
0
30
190
1.64
1.67
4.3
4.0
0.4
0.5
%
—
5
48
37
248
1.55
1.64
1.5
1.4
—
—
—
0
0
5
14
3.61
1.62
1.0
1.2
—
—
—
0
0
80
1000
0.74
1.59
3.1
2.8
—
—
—
0
0
57
422
1.42
1.57
2.0
1.7
—
—
—
0
0
5
15
3.37
1.53
1.0
1.1
—
—
—
0
0
14
72
1.99
1.51
1.1
1.2
—
—
—
0
0
18
102
1.81
1.48
1.3
1.7
—
—
—
0
0
11
53
2.11
1.40
12.6
2.6
—
—
—
0
0
18
104
1.77
1.40
1.1
1.1
—
—
—
0
0
7
29
2.44
1.40
1.4
1.3
—
—
—
0
0
267
2500
1.36
1.38
26.6
14.1
39.4
40.3
%
0.92
194
1846
283
2678
1.41
1.34
4.6
4.3
4.6
4.7
mmol/l
1.41
263
2482
18
106
1.74
1.32
1.0
1.2
—
—
—
0
0
277
2614
1.38
1.31
5.1
4.3
6.0
5.9
mmol/l
0.43
250
2385
282
2669
1.40
1.31
4.5
4.2
1.5
1.5
mmol/l
0.36
259
2462
6
24
2.53
1.31
2.5
2.4
—
—
—
0
0
26
170
1.57
1.30
1.1
1.2
146.2
122.9
iu/ml
—
9
69
8
34
2.39
1.30
1.1
1.1
—
—
—
0
0
5
18
2.80
1.29
2.6
1.2
—
—
—
0
0
8
35
2.32
1.27
1.0
1.2
—
—
—
0
0
41
298
1.43
1.26
1.9
1.7
—
—
—
0
0
5
19
2.66
1.22
1.2
1.2
—
—
—
0
0
5
19
2.66
1.22
3.0
2.8
—
—
—
0
0
16
94
1.74
1.19
1.2
1.2
—
—
—
0
0
31
216
1.48
1.19
4.6
4.0
1.0
1.2
%
—
6
69
98
823
1.27
1.17
3.4
2.3
—
—
—
0
0
272
2573
1.33
1.16
4.1
3.9
1.3
1.3
mmol/l
0.21
247
2371
91
759
1.28
1.15
3.2
2.9
—
—
—
0
0
11
58
1.93
1.13
2.1
2.9
8.3
8.6
kpa
0.23
11
58
11
58
1.93
1.13
2.5
2.9
1.4
2.4
mmol/l
—
6
36
11
58
1.93
1.13
2.5
2.9
5.1
5.0
kpa
0.24
11
58
15
88
1.74
1.13
1.5
1.3
—
—
—
0
0
7
30
2.36
1.13
1.3
1.1
—
—
—
0
0
64
511
1.31
1.12
2.1
1.8
—
—
—
0
0
286
2734
1.35
1.05
5.4
4.8
2.7
2.8
mmol/l
0.77
266
2521
31
222
1.44
1.05
5.7
3.9
—
—
—
0
0
16
98
1.66
1.05
7.9
9.0
1.1
0.9
%
2.74
16
90
88
740
1.26
1.03
4.2
3.1
634.9
406.6
mg/l
0.14
64
484
95
808
1.25
1.01
4.2
2.9
6.9
7.7
mmol/l
1.57
81
680
0
30
0.00
0.97
0.0
1.5
—
—
—
0
0
92
784
1.24
0.96
5.2
3.8
4.3
9.4
mg/mmol
1.86
65
492
147
1315
1.21
0.96
4.0
3.4
0.0
0.0
estimate
0.00
23
265
17
109
1.59
0.95
3.3
2.0
7.2
3.8
ug/l
0.30
17
101
15
93
1.64
0.95
1.3
1.5
241.0
236.4
miu/ml
—
5
45
32
236
1.39
0.94
1.6
1.4
—
—
—
0
0
6
27
2.24
0.94
1.7
1.0
—
—
—
0
0
19
126
1.54
0.93
8.3
2.2
1.2
1.3
%
0.13
19
126
32
238
1.38
0.90
21.3
5.7
1.2
1.4
mmol/l
0.60
32
230
10
57
1.78
0.84
1.4
1.9
—
—
—
0
0
26
189
1.41
0.84
4.0
4.3
0.0
0.2
%
—
5
54
134
1202
1.19
0.83
10.5
9.2
0.0
0.0
e9/l
0.80
107
986
25
181
1.41
0.82
6.0
7.3
—
—
—
0
0
6
32
1.89
0.82
1.5
1.4
—
—
—
0
0
19
131
1.48
0.80
2.2
2.2
—
—
—
0
0
29
217
1.37
0.80
5.2
3.1
—
—
—
0
0
6
33
1.83
0.79
4.5
4.3
375.2
342.1
umol/l
—
6
28
33
253
1.34
0.79
1.6
1.7
—
—
—
0
0
68
574
1.23
0.78
4.1
3.6
1.0
1.0
kg/l
—
5
68
15
99
1.54
0.77
8.3
9.0
1.7
1.6
%
0.13
15
90
9
53
1.72
0.76
1.0
1.3
—
—
—
0
0
145
1320
1.18
0.74
5.2
4.5
0.0
0.0
estimate
0.50
23
259
13
84
1.57
0.73
1.5
1.6
—
—
—
0
0
261
2499
1.21
0.72
6.7
5.4
40.0
39.7
mmol/mol
0.20
243
2334
146
1334
1.17
0.70
4.0
3.4
0.0
0.0
estimate
0.00
22
250
7
41
1.72
0.70
1.0
1.0
—
—
—
0
0
23
170
1.38
0.69
3.3
2.6
3.1
3.8
e9/l
0.79
15
133
64
744
0.83
0.67
4.3
3.0
—
—
—
0
0
16
111
1.46
0.67
3.0
1.9
1.5
1.6
g/l
0.11
16
97
5
28
1.80
0.66
3.8
1.4
—
—
—
0
0
10
62
1.63
0.66
3.1
2.3
—
—
—
0
0
7
44
1.60
0.65
1.1
1.2
214.3
14.5
u/l
—
7
37
61
522
1.21
0.62
1.5
1.8
238461941.3
445.6
pmol/l
0.49
52
437
10
63
1.61
0.62
1.1
1.1
—
—
—
0
0
297
2895
1.27
0.59
14.2
9.9
26.1
26.6
u/l
0.17
291
2790
26
203
1.30
0.57
4.1
4.2
0.0
0.2
%
—
5
60
8
54
1.49
0.57
1.6
1.7
—
—
—
0
0
14
98
1.45
0.57
5.4
3.3
0.2
0.2
g/l
—
7
37
17
125
1.38
0.55
3.2
3.2
—
—
—
0
0
79
702
1.16
0.53
1.7
1.6
1.2
1.4
mmol/l
1.75
73
587
84
753
1.16
0.51
1.6
1.5
—
—
—
0
0
13
93
1.41
0.49
1.8
2.8
—
—
—
0
0
10
68
1.49
0.47
2.3
2.0
123.6
131.1
g/l
—
5
46
56
492
1.17
0.44
2.2
2.7
0.6
0.8
ug/l
2.22
40
305
21
166
1.28
0.44
1.3
1.2
—
—
—
0
0
7
51
1.38
0.44
1.0
1.1
—
—
—
0
0
5
31
1.62
0.43
1.2
1.8
87.8
89.7
%
—
5
31
5
31
1.62
0.43
1.2
1.2
—
—
—
0
0
8
56
1.44
0.43
1.1
1.3
3.6
3.7
mmol/l
—
8
50
5
32
1.57
0.42
1.6
2.6
—
—
—
0
0
15
194
0.76
0.41
1.4
1.4
—
—
—
0
0
11
79
1.41
0.41
13.0
2.2
1863.8
831.3
ug/l
0.26
11
74
0
16
0.00
0.41
0.0
1.7
—
—
—
0
0
0
17
0.00
0.41
0.0
1.6
—
—
—
0
0
0
18
0.00
0.40
0.0
2.1
—
3.6
—
0
18
48
423
1.16
0.38
1.3
1.2
9.7
9.0
u/ml
0.03
22
165
5
37
1.36
0.37
1.2
1.1
—
—
—
0
0
5
37
1.36
0.37
1.2
1.1
—
—
—
0
0
5
37
1.36
0.37
4.8
3.4
—
—
—
0
0
91
839
1.12
0.37
4.1
4.5
1.5
2.0
ug/l
2.28
84
753
21
171
1.24
0.36
1.3
1.2
—
—
—
0
0
24
282
0.84
0.31
1.1
1.3
—
—
—
0
0
12
93
1.30
0.30
7.4
9.2
—
—
—
0
0
8
63
1.28
0.28
2.6
4.0
—
—
—
0
0
9
116
0.77
0.28
1.8
1.7
—
—
—
0
0
9
120
0.74
0.27
1.0
1.1
—
—
—
0
0
49
444
1.12
0.27
1.4
1.3
11.2
34.6
iu/ml
3.94
16
150
19
160
1.20
0.26
1.2
1.3
—
49.6
—
0
13
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
14
166
0.84
0.21
8.3
3.6
5.2
5.1
kpa
0.20
14
158
6
48
1.25
0.20
1.2
1.4
—
—
—
0
0
6
49
1.23
0.20
3.7
1.6
—
—
—
0
0
68
721
0.93
0.19
3.5
3.7
—
—
—
0
0
21
185
1.14
0.18
2.1
2.4
—
22.5
—
0
7
10
121
0.82
0.18
9.6
3.9
—
—
—
0
0
7
59
1.19
0.18
10.7
1.3
1.0
0.9
nmol/l
—
7
50
7
61
1.15
0.17
1.6
1.5
—
—
—
0
0
7
61
1.15
0.17
1.7
1.5
—
—
—
0
0
32
293
1.10
0.16
2.2
4.1
21.7
22.2
ug/l
0.01
23
246
63
599
1.06
0.14
1.4
1.2
0.4
1.1
u/ml
—
9
178
8
98
0.81
0.14
3.1
1.6
—
—
—
0
0
19
170
1.12
0.14
1.5
2.3
—
—
—
0
0
9
106
0.84
0.13
2.9
1.6
—
—
—
0
0
9
106
0.84
0.13
2.9
1.6
—
—
—
0
0
9
106
0.84
0.13
2.9
1.6
—
—
—
0
0
9
107
0.84
0.13
2.9
1.6
—
—
—
0
0
56
537
1.05
0.09
1.5
1.4
2.2
2.4
g/l
0.12
31
335
37
351
1.06
0.09
1.2
1.2
—
—
—
0
0
7
64
1.10
0.08
1.7
1.6
—
—
—
0
0
27
286
0.94
0.07
1.4
1.3
—
—
—
0
0
23
241
0.95
0.04
6.0
3.3
—
—
—
0
0
11
102
1.08
0.03
4.9
5.4
—
—
—
0
0
26
259
1.00
0.00
1.4
1.4
—
—
—
0
0
73
734
0.99
0.00
5.1
3.6
0.0
0.0
estimate
0.50
22
257
0
5
0.00
0.00
0.0
1.4
—
76.9
—
0
5
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
6
64
0.94
0.00
3.0
2.3
23.0
24.9
mmol/l
—
6
56
5
55
0.91
0.00
1.2
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
15.1
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
0
8
0.00
0.00
0.0
2.1
—
1.2
—
0
8
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
2.1
—
0
5
0
8
0.00
0.00
0.0
1.6
—
162.2
—
0
8
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
5
50
1.00
0.00
3.8
2.2
—
—
—
0
0
7
72
0.97
0.00
9.4
3.4
2.0
1.4
mg/l
—
7
64
7
74
0.94
0.00
3.3
1.9
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
40.0
—
0
6
18
180
1.00
0.00
1.7
2.2
—
—
—
0
0
0
7
0.00
0.00
0.0
4.1
—
6.3
—
0
7
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
8
84
0.95
0.00
3.1
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
2.5
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint H7_CONJUNAS and mortality.

Females

Parameter HR [95% CI] p-value
H7_CONJUNAS 0.931 [0.7, 1.24] 0.623
Birth year 0.999 [0.99, 1.01] 0.831

During the follow-up period (1.1.1998 — 31.12.2019), 71 out of 895 females with H7_CONJUNAS died.

Males

Parameter HR [95% CI] p-value
H7_CONJUNAS 1.148 [0.85, 1.55] 0.366
Birth year 0.983 [0.97, 0.99] < 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 107 out of 871 males with H7_CONJUNAS died.

Mortality risk

Mortality risk for people of age

years, who have H7_CONJUNAS.

N-year risk Females Males
1 0.09% 0.194%
5 0.57% 1.137%
10 1.522% 2.871%
15 3.012% 5.649%
20 5.316% 9.392%

Relationships between endpoints

Index endpoint: H7_CONJUNAS – Other specified and unspecified disorders of conjunctiva

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data