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This is a non-core endpoint: only basic statistics are computed.

Malignant neoplasm of other and unspecified urinary organs

C3_URINARY_TRACT_NAS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 C68
  • Cause of death: ICD-9 189[4-9]
  • Cause of death: ICD-8 1899
  • Cancer registry: Topography ICD-O-3 C68
  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes 3

2 out of 7 registries used, show all original rules.

105

4. Check minimum number of events

None

105

5. Include endpoints

None

105

6. Filter based on genotype QC (FinnGen only)

99

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF9

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 99 31 68
Unadjusted period prevalence (%) 0.02 0.01 0.03
Median age at first event (years) 73.66 70.71 75.00

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
105
Matched controls
1050
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
UKC02
NOMESCO Finland
Cystoscopy
43.1
75.5
89
120
C67.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of bladder
+∞
55.1
48
*
KCD02
NOMESCO Finland
Transurethral resection of bladder
674.7
46.0
42
*
R31
ICD-10 Finland
Unspecified haematuria
13.7
41.9
58
87
130
Kela drug reimbursment
Malignant tumour
+∞
35.4
32
*
8120/3-C68.9
ICD-O-3
Transitional cell carcinoma, NOS, of urinary system, NOS
+∞
35.4
32
*
C65
ICD-10 Finland
Malignant neoplasm of renal pelvis
+∞
29.6
27
*
C67.9
ICD-10 Finland
Malignant neoplasm: Bladder, unspecified
+∞
28.4
26
*
KBJ10
NOMESCO Finland
Cutaneous ureteroenterostomy
+∞
26.1
24
*
KCD05
NOMESCO Finland
Excision of bladder lesion during urinary tract endoscopy with photodynamic diagnosis (PDD)
324.0
25.9
25
*
H02AB02
ATC
dexamethasone; systemic
324.0
25.9
25
*
JN4AD
NOMESCO Finland
Body CT examination
12.5
25.7
29
31
C68.0
ICD-10 Finland
Malignant neoplasm: Urethra
+∞
23.9
22
*
UKB02
NOMESCO Finland
Retrograde ureteroscopy
107.9
23.8
25
*
A03FA01
ATC
metoclopramide; systemic, rectal
9.4
23.8
35
53
UKC05
NOMESCO Finland
Cystoscopy and bladder biopsy
153.7
23.7
24
*
KAC20
NOMESCO Finland
Nephroureterectomy
+∞
22.7
21
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
+∞
21.6
20
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
21.6
20
*
C66
ICD-10 Finland
Malignant neoplasm of ureter
+∞
20.5
19
*
Z51.5
ICD-10 Finland
Palliative care
19.5
19.6
30
21
D41.4
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bladder
86.4
19.5
21
*
WX408
NOMESCO Finland
General anesthesy, balanced
6.3
19.5
48
123
KCD32
NOMESCO Finland
Cystoscopic destruction of tumour of bladder
122.2
19.3
20
*
8120/3-C68.0
ICD-O-3
Transitional cell carcinoma, NOS, of urethra
+∞
18.2
17
*
B01AB10
ATC
tinzaparin; parenteral
9.7
18.2
24
31
ZX136
NOMESCO Finland
Intravesicalis
+∞
17.1
16
*
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
17.1
16
*
KBV02
NOMESCO Finland
Cystoscopic insertion of stent into ureter
48.7
17.0
20
5
N13.3
ICD-10 Finland
Other and unspecified hydronephrosis
36.9
16.9
21
7
WX302
NOMESCO Finland
Thoracal epidural anesthesy
30.4
15.4
20
8
XKD00
NOMESCO Finland
Uroflowmetry
5.3
15.0
42
117
8120/3-C68.8
ICD-O-3
Transitional cell carcinoma, NOS, of overlapping lesion of urinary organs
+∞
14.9
14
*
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
7.9
14.8
23
36
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
19.5
14.7
22
14
J01EA01
ATC
trimethoprim; systemic
5.0
14.6
47
147
JN4CD
NOMESCO Finland
Very extensive body CT
40.0
14.0
17
5
C67.2
ICD-10 Finland
Malignant neoplasm: Lateral wall of bladder
+∞
13.8
13
*
C68.9
ICD-10 Finland
Malignant neoplasm: Urinary organ, unspecified
+∞
13.8
13
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
13.8
13
*
XX3DW
NOMESCO Finland
Time consuming IT work
16.0
13.7
22
17
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
5.0
13.5
40
116
KH1CD
NOMESCO Finland
Very extensive urinary tract ultrasound examination
79.8
12.9
14
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
+∞
12.8
12
*
8000/3-C68.9
ICD-O-3
Neoplasm, malignant of urinary system, NOS
+∞
12.8
12
*
KCC10
NOMESCO Finland
Cystoprostatectomy
+∞
12.8
12
*
D41.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Renal pelvis
146.8
12.7
13
*
KH1BT
NOMESCO Finland
Urinary tract cathetrisation with X-ray guidance
146.8
12.7
13
*
R33
ICD-10 Finland
Retention of urine
5.2
12.6
32
81
J01MA02
ATC
ciprofloxacin; systemic
4.2
12.0
65
291
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
5.5
11.8
27
62
A04AA02
ATC
granisetron; systemic, transdermal
+∞
11.7
11
*
KAC21
NOMESCO Finland
Percutaneous endoscopic nephroureterectomy
+∞
11.7
11
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
11.7
11
*
TKC20
NOMESCO Finland
Catheterisation of bladder
5.8
11.4
24
51
C67.0
ICD-10 Finland
Malignant neoplasm: Trigone of bladder
+∞
10.6
10
*
D41.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Urethra
+∞
10.6
10
*
WZC00
NOMESCO Finland
Treatment plan or consultation
4.0
10.2
39
134
J01CA08
ATC
pivmecillinam; oral
3.7
9.6
45
177
PJD54
NOMESCO Finland
Block dissection of iliac lymph nodes
+∞
9.5
9
*
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
9.5
9
*
116
Kela drug reimbursment
Prostate cancer
+∞
9.5
9
*
J01MA12
ATC
levofloxacin; systemic
3.9
9.5
37
128
TPH07
NOMESCO Finland
Cathetrisation of artery
4.8
9.2
24
61
A04AA01
ATC
ondansetron; systemic, rectal
15.9
9.0
14
10
N30.0
ICD-10 Finland
Acute cystitis
4.5
9.0
26
72
WF002
NOMESCO Finland
Radical radiotherapy
54.7
8.8
10
*
JN4BD
NOMESCO Finland
Extensive body CT
8.3
8.7
19
27
D41.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Ureter
+∞
8.4
8
*
R82.8
ICD-10 Finland
Abnormal findings on cytological and histological examination of urine
+∞
8.4
8
*
WC305
NOMESCO Finland
Simple therapy of local tumor recidive with biomodifiers
+∞
8.4
8
*
TJF80
NOMESCO Finland
Ostomy education
+∞
8.4
8
*
KCC30
NOMESCO Finland
Cystectomy with excision of female internal genital organs
+∞
8.4
8
*
WX402
NOMESCO Finland
General anaesthesia
4.3
8.1
24
67
ZXE30
NOMESCO Finland
More than five and less than seven hours
10.1
7.9
15
17
WZC30
NOMESCO Finland
Teaching
4.5
7.8
22
59
ZXE10
NOMESCO Finland
More than one and less than three hours
3.1
7.6
50
236
KH1BD
NOMESCO Finland
Extensive urinary tract CT examination
85.9
7.5
8
*
8070/3-C68.0
ICD-O-3
Squamous cell carcinoma, NOS, of urethra
+∞
7.4
7
*
C68.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of urinary organs
+∞
7.4
7
*
308
Kela drug reimbursment
Alprostadil, sildenafil and combination product containing aviptadil and phentolamine
+∞
7.4
7
*
UKA02
NOMESCO Finland
Retrograde ureteronephroscopy
+∞
7.4
7
*
YL1BD
NOMESCO Finland
Extensive CT examination of pelvis for dose design of radiotherapy
+∞
7.4
7
*
ZX070
NOMESCO Finland
Intensity modified radiotherapy
+∞
7.4
7
*
KA1AE
NOMESCO Finland
Kidney ultrasound examination
13.4
7.3
12
10
ZXE20
NOMESCO Finland
More than three and less than five hours
3.8
7.1
25
79
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
42.9
6.9
8
*
N02AA05
ATC
oxycodone; systemic
3.4
6.7
30
111
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
15.6
6.5
10
7
TKW99
NOMESCO Finland
Other minor surgical procedure in urology
74.2
6.5
7
*
U99
ICPC
Urinary disease other
28.6
6.3
8
*
KCC20
NOMESCO Finland
Cystoprostatourethrectomy
+∞
6.3
6
*
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
+∞
6.3
6
*
L01BC06
ATC
capecitabine; oral
+∞
6.3
6
*
YL1AD
NOMESCO Finland
CT examination of pelvis for dose design of radiotherapy
+∞
6.3
6
*
L02AE02
ATC
leuprorelin; implant, parenteral
+∞
6.3
6
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
6.3
6
*
U76
ICPC
Malignant neoplasm of bladder
+∞
6.3
6
*
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
+∞
6.3
6
*
ZX090
NOMESCO Finland
Other technic of radiotherapy
+∞
6.3
6
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
6.3
6
*
A04AD12
ATC
aprepitant; systemic
+∞
6.3
6
*
C67
ICD-10 Finland
Malignant neoplasm of bladder
+∞
6.3
6
*
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
3.8
6.1
21
65
SPAT1125
SPAT
Stoma care and guidance
16.2
6.0
9
6

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
55
29
38.73
75.45
6.1
2.0
—
—
—
0
0
68
235
6.37
19.84
7.1
3.3
—
—
—
0
0
28
47
7.76
17.06
1.5
1.0
—
—
—
0
0
24
18
16.89
15.14
1.6
1.1
—
—
—
0
0
52
193
4.36
12.60
3.6
1.5
—
—
—
0
0
32
95
4.41
10.18
12.7
5.8
105.59
104.38
mmol/l
0.53
32
95
55
250
3.52
9.29
9.1
3.1
335.70
370.00
e6/l
0.04
50
193
52
236
3.38
8.68
6.4
3.9
—
—
—
0
0
22
55
4.80
8.57
18.5
9.0
—
—
—
0
0
49
221
3.28
8.16
3.0
2.1
—
—
—
0
0
80
490
3.66
7.84
12.4
4.8
—
29.77
—
0
13
46
210
3.12
7.36
10.1
2.8
—
—
—
0
0
55
278
3.05
7.36
10.7
3.8
781.20
85.72
e6/l
0.86
50
202
25
78
3.89
7.26
8.8
4.4
5.91
5.77
kpa
0.29
25
72
78
508
3.08
6.15
8.2
4.3
—
—
—
0
0
57
318
2.73
6.01
7.6
3.2
32.29
34.79
g/l
2.66
52
295
31
125
3.10
5.99
9.8
3.2
2.45
2.07
e6/l
0.11
22
69
59
348
2.59
5.39
6.9
4.0
0.00
0.00
estimate
-0.00
21
61
32
145
2.74
4.92
2.3
1.7
29.91
29.04
s
0.50
32
139
58
354
2.43
4.73
9.4
5.2
0.00
0.00
estimate
-0.00
18
53
60
375
2.40
4.60
14.0
5.2
4.91
4.46
e9/l
0.46
53
322
58
358
2.39
4.57
6.9
3.9
0.00
0.00
estimate
-0.00
19
48
61
387
2.38
4.48
14.9
5.8
1.22
1.21
mmol/l
0.18
48
332
14
35
4.45
4.29
18.5
8.0
—
—
—
0
0
41
229
2.30
3.94
8.8
3.5
7.37
7.39
ph
1.28
12
37
15
50
3.33
3.87
7.6
3.5
—
—
—
0
0
31
156
2.40
3.75
6.0
4.0
—
—
—
0
0
23
101
2.64
3.69
13.6
6.3
-1.62
1.50
mmol/l
2.17
16
80
63
431
2.15
3.56
16.7
18.5
1.36
1.42
inr
0.18
17
123
47
307
1.96
2.83
7.4
5.1
—
—
—
0
0
47
308
1.95
2.80
6.9
4.8
0.65
0.63
%
0.08
41
279
48
320
1.92
2.69
6.7
4.9
3.05
3.10
%
0.04
42
290
48
322
1.90
2.63
6.9
5.2
9.25
8.82
%
0.42
42
290
15
63
2.61
2.60
6.5
3.4
—
—
—
0
0
51
350
1.89
2.60
7.0
4.5
0.20
0.20
e9/l
0.12
44
296
9
27
3.55
2.46
1.1
1.2
—
—
—
0
0
48
329
1.85
2.41
7.1
5.1
19.38
25.23
%
2.76
42
301
33
202
1.92
2.33
7.6
4.2
0.00
0.00
estimate
-0.00
14
53
47
325
1.81
2.26
6.7
4.8
64.38
58.91
%
1.85
41
295
5
9
5.77
2.24
1.2
3.3
59.80
61.44
%
—
5
9
48
335
1.80
2.23
7.2
4.5
0.72
0.62
e9/l
1.10
39
285
48
336
1.79
2.21
7.1
4.5
0.04
0.04
e9/l
0.62
39
285
26
152
1.94
2.08
9.3
4.0
—
—
—
0
0
48
343
1.74
2.01
7.2
4.6
1.52
1.78
e9/l
1.54
41
298
5
11
4.71
1.96
1.2
1.1
—
—
—
0
0
25
149
1.89
1.89
2.8
2.2
2.48
2.43
mmol/l
0.96
20
120
11
48
2.44
1.77
1.6
1.3
—
—
—
0
0
5
13
3.98
1.73
3.4
1.2
34.60
85.69
u/ml
—
5
13
41
291
1.67
1.71
18.8
8.3
0.00
0.00
e9/l
-0.00
35
234
20
115
1.91
1.67
3.5
1.9
—
—
—
0
0
11
51
2.29
1.57
3.3
3.9
0.50
1.00
%
—
6
17
13
66
2.11
1.51
7.2
3.4
4.61
4.59
kpa
0.01
13
60
31
216
1.62
1.35
2.6
2.2
3.20
2.87
mg/l
0.39
23
181
29
199
1.63
1.34
7.1
3.6
—
—
—
0
0
10
48
2.20
1.32
3.5
4.1
0.20
0.14
%
—
5
14
9
44
2.14
1.30
5.2
4.0
—
—
—
0
0
6
25
2.48
1.26
9.7
5.1
1.62
1.15
mmol/l
—
6
25
8
37
2.26
1.24
5.0
4.0
—
—
—
0
0
8
37
2.26
1.24
9.1
2.9
0.64
0.58
%
—
8
37
6
26
2.38
1.20
10.3
4.0
—
—
—
0
0
12
65
1.96
1.19
5.5
4.1
—
—
—
0
0
8
39
2.14
1.18
9.1
2.9
1.18
1.04
%
—
8
39
23
154
1.63
1.16
1.2
1.2
—
—
—
0
0
5
20
2.57
1.16
5.2
3.1
—
—
—
0
0
64
541
1.47
1.09
4.9
4.3
—
—
—
0
0
9
47
2.00
1.05
1.8
1.4
—
—
—
0
0
12
70
1.81
0.97
6.0
1.7
500.50
361.52
nmol/l
1.08
12
62
33
258
1.41
0.81
4.5
4.4
—
—
—
0
0
81
735
1.45
0.81
32.3
14.4
—
—
—
0
0
0
24
0.00
0.80
0.0
4.4
—
28.60
—
0
16
83
758
1.45
0.78
42.1
17.7
128.48
87.87
umol/l
3.83
83
758
9
53
1.76
0.78
1.8
1.4
—
—
—
0
0
11
71
1.61
0.65
3.8
3.1
—
—
—
0
0
13
88
1.54
0.64
1.1
1.2
—
—
—
0
0
43
364
1.31
0.62
1.9
2.1
94.85
89.74
pmol/l
0.33
28
186
0
20
0.00
0.61
0.0
1.3
—
2.29
—
0
14
0
20
0.00
0.61
0.0
1.4
—
128.27
—
0
15
0
21
0.00
0.60
0.0
1.0
—
—
—
0
0
84
784
1.36
0.56
52.6
21.5
35.59
39.69
%
5.03
78
705
7
46
1.56
0.49
8.9
3.3
—
—
—
0
0
5
31
1.64
0.43
5.6
1.2
—
—
—
0
0
8
59
1.38
0.42
1.5
1.2
—
—
—
0
0
5
33
1.54
0.42
1.0
1.2
38.72
35.84
g/l
—
5
25
5
33
1.54
0.42
2.4
1.7
—
—
—
0
0
0
15
0.00
0.41
0.0
1.6
—
5.17
—
0
15
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
5
36
1.41
0.38
3.6
2.1
431.60
65.01
ug/min
—
5
27
11
81
1.40
0.38
1.3
1.5
—
—
—
0
0
12
92
1.34
0.33
2.8
1.9
—
—
—
0
0
17
204
0.80
0.30
3.0
3.7
—
—
—
0
0
8
62
1.31
0.29
1.3
1.3
—
—
—
0
0
49
530
0.86
0.28
5.3
3.4
15.16
14.88
pmol/l
0.30
41
464
75
718
1.16
0.23
5.2
5.2
5.98
6.15
mmol/l
0.57
64
636
44
407
1.14
0.22
4.7
4.1
6.89
2.31
ug/l
0.52
34
361
0
11
0.00
0.21
0.0
1.9
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
22
194
1.17
0.20
1.8
1.9
1137.24
1142.35
nmol/l
0.01
17
147
64
667
0.90
0.17
5.5
4.4
2.20
2.02
mu/l
0.34
53
585
40
374
1.11
0.16
5.7
4.0
49.13
57.06
ng/l
0.17
35
283
5
44
1.14
0.10
6.6
2.0
8.17
11.11
g/l
—
5
39
71
693
1.08
0.09
4.4
5.0
1.39
1.41
mmol/l
0.12
65
626
23
216
1.08
0.07
3.0
2.6
0.75
0.79
ug/l
0.10
17
154
29
305
0.93
0.07
3.7
3.8
24.85
7.25
mg/mmol
0.57
23
182
69
704
0.94
0.06
7.6
7.2
41.48
41.88
mmol/mol
0.12
61
644
74
728
1.06
0.05
4.7
5.7
2.34
2.50
mmol/l
0.90
67
660
68
670
1.04
0.03
4.4
4.5
1.21
1.22
mmol/l
0.11
62
600
71
701
1.04
0.02
4.6
5.0
4.16
4.30
mmol/l
0.59
65
639
20
208
0.95
0.02
1.9
2.0
299.20
408.39
pmol/l
2.98
15
169
28
283
0.99
0.00
2.9
3.1
6.04
7.34
mmol/l
1.36
23
233
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
93.20
—
0
5
0
6
0.00
-0.00
0.0
4.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.5
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
413.42
—
0
9
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
10.33
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
259.67
—
0
6
0
6
0.00
-0.00
0.0
2.8
—
8.20
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
191.00
—
0
5
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: C3_URINARY_TRACT_NAS – Malignant neoplasm of other and unspecified urinary organs

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).