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Malignant neoplasm of other and unspecified urinary organs, including Hilmo

C3_URINARY_TRACT_NAS_WIDE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 C68
  • Hospital discharge: ICD-9 189[4-9]
  • Hospital discharge: ICD-8 1899
  • Cause of death: ICD-10 C68
  • Cause of death: ICD-9 189[4-9]
  • Cause of death: ICD-8 1899
  • Cancer registry: Topography ICD-O-3 C68
  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes 3

3 out of 7 registries used, show all original rules.

268

4. Check minimum number of events

None

268

5. Include endpoints

None

268

6. Filter based on genotype QC (FinnGen only)

256

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

First used in FinnGen datafreeze
DF12

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 256 62 194
Unadjusted period prevalence (%) 0.07 0.02 0.09
Median age at first event (years) 71.01 69.11 71.61

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
268
Matched controls
2680
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
UKC02
NOMESCO Finland
Cystoscopy
21.0
143.8
194
297
C67.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of bladder
+∞
140.3
122
*
KCD02
NOMESCO Finland
Transurethral resection of bladder
376.1
118.2
111
5
130
Kela drug reimbursment
Malignant tumour
+∞
98.1
88
*
H02AB02
ATC
dexamethasone; systemic
56.1
93.3
54
12
R31
ICD-10 Finland
Unspecified haematuria
11.3
87.6
129
203
C67.9
ICD-10 Finland
Malignant neoplasm: Bladder, unspecified
919.9
73.9
69
*
C68.0
ICD-10 Finland
Malignant neoplasm: Urethra
+∞
73.4
67
*
C68.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of urinary organs
+∞
66.5
61
*
Z51.5
ICD-10 Finland
Palliative care
14.4
62.8
63
56
KCD05
NOMESCO Finland
Excision of bladder lesion during urinary tract endoscopy with photodynamic diagnosis (PDD)
748.5
62.4
59
*
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
17.5
62.3
55
39
C61
ICD-10 Finland
Malignant neoplasm of prostate
716.2
60.2
57
*
A03FA01
ATC
metoclopramide; systemic, rectal
9.2
60.2
91
142
C68.9
ICD-10 Finland
Malignant neoplasm: Urinary organ, unspecified
+∞
59.6
55
*
A04AA01
ATC
ondansetron; systemic, rectal
31.2
59.3
40
15
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
57.4
53
*
KBJ10
NOMESCO Finland
Cutaneous ureteroenterostomy
+∞
54.0
50
*
UKC05
NOMESCO Finland
Cystoscopy and bladder biopsy
219.1
53.0
53
*
8120/3-C67.9
ICD-O-3
Transitional cell carcinoma, NOS, of bladder, NOS
+∞
51.8
48
*
D41.4
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bladder
109.7
49.9
53
6
JN4AD
NOMESCO Finland
Body CT examination
10.3
49.6
63
78
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
+∞
49.5
46
*
WX302
NOMESCO Finland
Thoracal epidural anesthesy
21.3
47.4
37
20
C65
ICD-10 Finland
Malignant neoplasm of renal pelvis
+∞
45.1
42
*
KCD32
NOMESCO Finland
Cystoscopic destruction of tumour of bladder
131.0
42.2
44
*
B01AB10
ATC
tinzaparin; parenteral
8.9
41.2
58
81
JN4BD
NOMESCO Finland
Extensive body CT
9.7
40.3
52
65
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
8.6
38.9
56
80
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
38.5
36
*
C66
ICD-10 Finland
Malignant neoplasm of ureter
+∞
37.4
35
*
ZX136
NOMESCO Finland
Intravesicalis
138.0
34.6
36
*
8120/3-C68.9
ICD-O-3
Transitional cell carcinoma, NOS, of urinary system, NOS
+∞
34.1
32
*
C67.2
ICD-10 Finland
Malignant neoplasm: Lateral wall of bladder
+∞
34.1
32
*
WX408
NOMESCO Finland
General anesthesy, balanced
4.7
33.0
110
344
UKB02
NOMESCO Finland
Retrograde ureteroscopy
71.1
33.0
37
6
KAC20
NOMESCO Finland
Nephroureterectomy
+∞
31.9
30
*
PJD54
NOMESCO Finland
Block dissection of iliac lymph nodes
+∞
31.9
30
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
351.8
31.5
31
*
C64
ICD-10 Finland
Malignant neoplasm of kidney, except renal pelvis
+∞
30.8
29
*
A04AA02
ATC
granisetron; systemic, transdermal
+∞
30.8
29
*
XX3DW
NOMESCO Finland
Time consuming IT work
8.9
29.7
40
52
KCC10
NOMESCO Finland
Cystoprostatectomy
+∞
29.7
28
*
KBV02
NOMESCO Finland
Cystoscopic insertion of stent into ureter
31.3
28.9
38
14
TKC20
NOMESCO Finland
Catheterisation of bladder
6.0
28.8
59
121
116
Kela drug reimbursment
Prostate cancer
+∞
28.7
27
*
KH1CD
NOMESCO Finland
Very extensive urinary tract ultrasound examination
53.5
28.2
33
7
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
27.6
26
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
5.0
25.7
65
160
N13.3
ICD-10 Finland
Other and unspecified hydronephrosis
29.7
25.6
34
13
JN4CD
NOMESCO Finland
Very extensive body CT
23.5
24.6
35
17
8312/3-C64.9
ICD-O-3
Renal cell carcinoma, NOS, of kidney, NOS
+∞
24.3
23
*
J01MA02
ATC
ciprofloxacin; systemic
3.6
24.1
155
734
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
4.2
23.6
80
246
8130/2-C67.9
ICD-O-3
Papillary urothelial carcinoma, non-invasive of bladder, NOS
+∞
23.3
22
*
N02AA05
ATC
oxycodone; systemic
4.2
22.8
78
241
J01EA01
ATC
trimethoprim; systemic
3.8
22.7
96
344
ZXE30
NOMESCO Finland
More than five and less than seven hours
8.8
22.6
30
38
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
+∞
22.2
21
*
KA1AE
NOMESCO Finland
Kidney ultrasound examination
9.5
21.0
26
30
D41.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Renal pelvis
226.9
20.9
21
*
WZC00
NOMESCO Finland
Treatment plan or consultation
3.6
20.8
97
368
TPH07
NOMESCO Finland
Cathetrisation of artery
4.4
20.2
59
161
D41.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Urethra
+∞
20.0
19
*
KCC20
NOMESCO Finland
Cystoprostatourethrectomy
+∞
20.0
19
*
KH1BT
NOMESCO Finland
Urinary tract cathetrisation with X-ray guidance
79.4
20.0
22
*
WF002
NOMESCO Finland
Radical radiotherapy
113.5
19.9
21
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
215.2
19.8
20
*
D41.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Kidney
20.7
19.1
28
15
D41.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Ureter
+∞
19.0
18
*
WC305
NOMESCO Finland
Simple therapy of local tumor recidive with biomodifiers
+∞
19.0
18
*
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
19.0
18
*
U76
ICPC
Malignant neoplasm of bladder
+∞
19.0
18
*
C67.0
ICD-10 Finland
Malignant neoplasm: Trigone of bladder
+∞
19.0
18
*
8120/3-C68.0
ICD-O-3
Transitional cell carcinoma, NOS, of urethra
+∞
19.0
18
*
TJF80
NOMESCO Finland
Ostomy education
107.7
18.8
20
*
WX402
NOMESCO Finland
General anaesthesia
4.0
18.5
63
192
XKD00
NOMESCO Finland
Uroflowmetry
3.3
17.7
90
356
J01MA12
ATC
levofloxacin; systemic
3.4
17.3
82
310
L02AE02
ATC
leuprorelin; implant, parenteral
+∞
16.8
16
*
8310/3-C64.9
ICD-O-3
Clear cell adenocarcinoma, NOS, of kidney, NOS
+∞
16.8
16
*
A04AD12
ATC
aprepitant; systemic
+∞
16.8
16
*
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
7.9
16.8
24
33
U06
ICPC
Haematuria
13.4
16.8
29
24
JN3AD
NOMESCO Finland
Abdominal CT examination
4.3
16.1
47
127
KAC21
NOMESCO Finland
Percutaneous endoscopic nephroureterectomy
+∞
15.8
15
*
R82.8
ICD-10 Finland
Abnormal findings on cytological and histological examination of urine
+∞
15.8
15
*
WZC30
NOMESCO Finland
Teaching
3.9
15.7
52
154
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
169.5
15.6
16
*
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
3.2
15.2
75
288
N30.0
ICD-10 Finland
Acute cystitis
3.8
14.9
52
160
KCC30
NOMESCO Finland
Cystectomy with excision of female internal genital organs
+∞
14.7
14
*
KAC10
NOMESCO Finland
Total nephrectomy with capsule
+∞
14.7
14
*
8120/3-C68.8
ICD-O-3
Transitional cell carcinoma, NOS, of overlapping lesion of urinary organs
+∞
14.7
14
*
308
Kela drug reimbursment
Alprostadil, sildenafil and combination product containing aviptadil and phentolamine
+∞
14.7
14
*
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
+∞
14.7
14
*
YL1BD
NOMESCO Finland
Extensive CT examination of pelvis for dose design of radiotherapy
+∞
14.7
14
*
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
+∞
14.7
14
*
UKA02
NOMESCO Finland
Retrograde ureteronephroscopy
158.3
14.6
15
*
WX320
NOMESCO Finland
Spinalanesthesy
2.9
14.1
93
419
JN3BD
NOMESCO Finland
Extensive abdominal CT
4.2
14.0
41
111
KH1BD
NOMESCO Finland
Extensive urinary tract CT examination
56.5
14.0
16
*
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
+∞
13.7
13
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
13.7
13
*
WC105
NOMESCO Finland
Simple cytostatic therapy of local tumor recidive
+∞
13.7
13
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
3.3
13.4
59
210
B01AB05
ATC
enoxaparin; parenteral
2.7
12.7
99
482
KC1GB
NOMESCO Finland
Cystography with X-ray
73.4
12.7
14
*
KCB00
NOMESCO Finland
Biopsy of bladder
73.4
12.7
14
*
KBV12
NOMESCO Finland
Transluminal endoscopic removal of stent from ureter
18.5
12.7
19
11
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
12.6
12
*
L01BC06
ATC
capecitabine; oral
+∞
12.6
12
*
L03AA02
ATC
filgrastim; parenteral
+∞
12.6
12
*
8000/3-C68.9
ICD-O-3
Neoplasm, malignant of urinary system, NOS
+∞
12.6
12
*
B02AA02
ATC
tranexamic acid; systemic
4.1
12.6
38
105
R33
ICD-10 Finland
Retention of urine
3.2
12.5
57
207
JEA00
NOMESCO Finland
Appendectomy
6.2
12.5
22
38
KDD32
NOMESCO Finland
Urethroscopic destruction of tumour of urethra
+∞
11.5
11
*
ZX070
NOMESCO Finland
Intensity modified radiotherapy
+∞
11.5
11
*
YL1AD
NOMESCO Finland
CT examination of pelvis for dose design of radiotherapy
+∞
11.5
11
*
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
+∞
11.5
11
*
TPH04
NOMESCO Finland
Cathetrisation of vein
2.7
11.4
75
333
KH1AD
NOMESCO Finland
CT of urinary organs
5.9
11.4
21
38
SPAT1125
SPAT
Stoma care and guidance
15.0
10.6
17
12
ZX090
NOMESCO Finland
Other technic of radiotherapy
114.3
10.5
11
*
KDC00
NOMESCO Finland
Urethrectomy
+∞
10.5
10
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
10.5
10
*
A04AA55
ATC
palonosetron, combinations; systemic
+∞
10.5
10
*
C67
ICD-10 Finland
Malignant neoplasm of bladder
+∞
10.5
10
*
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
34.0
10.4
13
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.3
10.4
146
911
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
5.3
10.2
21
42
J01CA08
ATC
pivmecillinam; oral
2.5
10.2
82
400
KCW02
NOMESCO Finland
Lavation of bladder for coagulated blood
12.9
10.0
17
14
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
5.0
10.0
22
47
TKW99
NOMESCO Finland
Other minor surgical procedure in urology
21.0
9.9
14
7
N17.9
ICD-10 Finland
Acute renal failure, unspecified
4.3
9.8
26
65
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
9.6
9.7
19
21
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
4.3
9.6
26
66
JN2CG
NOMESCO Finland
Extensive MRI examination of lower part of abdoment with high intensity magnet
31.3
9.5
12
*
7125
FHL
Nephrectomy (extrrafascial)
103.5
9.5
10
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
9.4
9
*
1899X
ICD-9 Finland
Malignant neoplasm of kidney and other and unspecified urinary organs, Urinary organ, site unspecified[NEOPLASMA MAL ORG URIN NUD,EI HIST VAHV]
+∞
9.4
9
*
KBD00
NOMESCO Finland
Partial excision of ureter
+∞
9.4
9
*
A79
ICPC
Malignancy NOS
+∞
9.4
9
*
L02BB03
ATC
bicalutamide; oral
+∞
9.4
9
*
ZX120
NOMESCO Finland
Intravenous
3.6
9.4
32
96
ZXE10
NOMESCO Finland
More than one and less than three hours
2.3
9.3
105
590
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
9.6
9.2
18
20
UKD02
NOMESCO Finland
Urethroscopy
25.0
9.0
12
5
Z3231
NOMESCO Finland
Registered nurse
2.3
8.8
83
431
KED22
NOMESCO Finland
Transurethral resection of prostate
3.0
8.7
41
151
WW500
NOMESCO Finland
Blood transfusion
7.8
8.6
19
26
ZXE20
NOMESCO Finland
More than three and less than five hours
2.8
8.6
49
200
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.6
8.6
56
245
PJD44
NOMESCO Finland
Excision of iliac lymph nodes
92.9
8.5
9
*
Y77
ICPC
Malignant neoplasm prostate
92.9
8.5
9
*
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
7.5
8.4
19
27
8120/3-C65.9
ICD-O-3
Transitional cell carcinoma, NOS, of renal pelvis
+∞
8.4
8
*
C67.1
ICD-10 Finland
Malignant neoplasm: Dome of bladder
+∞
8.4
8
*
KH1YT
NOMESCO Finland
Percutaneous implantation of endoprothesis with radiological guidance
+∞
8.4
8
*
WB121
NOMESCO Finland
Demanding neoadjuvant cytostatic therapy
+∞
8.4
8
*
YJ2VG
NOMESCO Finland
MRI examination of pelvis with high intensity magnet for dose design of radiotherapy
+∞
8.4
8
*
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
+∞
8.4
8
*
WD505
NOMESCO Finland
Simple enzyme inhibitor or similar therapy of methastized malignancy
+∞
8.4
8
*
C67.4
ICD-10 Finland
Malignant neoplasm: Posterior wall of bladder
+∞
8.4
8
*
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
8.4
8
*
KDV12
NOMESCO Finland
Urethroscopic internal urethrotomy
17.8
8.1
12
7
N30.9
ICD-10 Finland
Cystitis, unspecified
3.9
7.9
24
66
JFB00
NOMESCO Finland
Partial resection of small intestine
15.6
7.8
12
8
U07
ICPC
Urine symptom/complaint other
3.5
7.8
28
87
ZXD10
NOMESCO Finland
Scheduled procedure
2.1
7.7
109
662
KEC00
NOMESCO Finland
Retropubic radical prostatectomy
+∞
7.3
7
*
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
+∞
7.3
7
*
KH1FT
NOMESCO Finland
Exchange of urinary catheter with radiological guidance
+∞
7.3
7
*
C67.6
ICD-10 Finland
Malignant neoplasm: Ureteric orifice
+∞
7.3
7
*
U77
ICPC
Malignant neopl urinary tract other
+∞
7.3
7
*
KDD30
NOMESCO Finland
Destruction of tumour of urethra
+∞
7.3
7
*
KDD96
NOMESCO Finland
Other partial excision of urethra
+∞
7.3
7
*
8070/3-C68.0
ICD-O-3
Squamous cell carcinoma, NOS, of urethra
+∞
7.3
7
*
1890B
ICD-9 Finland
Malignant neoplasm of kidney and other and unspecified urinary organs, Kidney, except pelvis[NEOPL MAL RENIS PELVI EXCEPTO,ADENOCARCINOMA]
+∞
7.3
7
*
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
4.7
7.3
17
38
KA1FN
NOMESCO Finland
Isotope renography
30.9
7.2
9
*
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
3.4
7.2
26
81
U99
ICPC
Urinary disease other
12.5
7.1
12
10
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.9
7.1
36
138
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.7
6.9
39
158
TKC50
NOMESCO Finland
Training of urinary bladder
41.1
6.8
8
*
WX702
NOMESCO Finland
Supraglottic ventilation device
4.2
6.7
18
45
TKD00
NOMESCO Finland
Dilatation of urethra
23.2
6.7
9
*
ZXE00
NOMESCO Finland
One hour or less
2.0
6.7
103
637
R4110
NOMESCO Finland
Physiotherapy
2.1
6.7
76
421
KE1AT
NOMESCO Finland
Biopsy of prostata with ultrasoudnguidance
4.4
6.7
17
41
U05
ICPC
Urination problems other
3.4
6.6
24
75
G04BE03
ATC
sildenafil; oral
71.5
6.5
7
*
8120/2-C67.9
ICD-O-3
Urothelial carcinoma in situ of bladder, NOS
71.5
6.5
7
*
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
71.5
6.5
7
*
ZXD05
NOMESCO Finland
Urgent procedure
2.0
6.4
86
507
KBJ60
NOMESCO Finland
Anastomosis of ureter to urethra with interposition of ileum
+∞
6.3
6
*
PJA12
NOMESCO Finland
Sentinel node biopsy
+∞
6.3
6
*
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
+∞
6.3
6
*
KDW96
NOMESCO Finland
Other operations on urethra
+∞
6.3
6
*
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
+∞
6.3
6
*
D09.0
ICD-10 Finland
Carcinoma in situ: Bladder
+∞
6.3
6
*
180
Kela drug reimbursment
Interferon alfa
+∞
6.3
6
*
KAC00
NOMESCO Finland
Nephrectomy
+∞
6.3
6
*
D41.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Urinary organ, unspecified
+∞
6.3
6
*
KAC11
NOMESCO Finland
Total nephrectomy with capsule, transcutaneous
+∞
6.3
6
*
1888X
ICD-9 Finland
Malignant neoplasm of bladder, Other specified sites of bladder
+∞
6.3
6
*
KA3EB
NOMESCO Finland
Antegrade pyelography
+∞
6.3
6
*
115
Kela drug reimbursment
Breast cancer
+∞
6.3
6
*
C64.80
ICD-10 Finland
Wilms tumour
+∞
6.3
6
*
KA3GB
NOMESCO Finland
Retrograde pyelography
+∞
6.3
6
*
159
Kela drug reimbursment
Pazopanib
+∞
6.3
6
*
R50.9
ICD-10 Finland
Fever, unspecified
2.4
6.2
44
199
ZXA05
NOMESCO Finland
Left side
2.0
6.2
79
455
R60.0
ICD-10 Finland
Localized oedema
2.5
6.2
42
186
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
4.3
6.2
16
39

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
132
72
35.16
178.10
5.7
1.8
—
—
—
0
0
59
44
16.91
65.15
1.5
1.2
—
—
—
0
0
69
125
7.09
38.73
1.7
1.1
—
—
—
0
0
140
506
4.70
35.18
3.9
1.6
—
—
—
0
0
89
253
4.77
29.81
10.8
6.3
105.64
104.75
mmol/l
0.92
89
253
141
586
3.97
27.71
7.3
3.0
—
—
—
0
0
138
605
3.64
24.25
8.8
3.1
195.35
191.99
e6/l
0.01
116
473
109
420
3.69
23.20
5.1
2.4
5.44
3.97
e6/l
0.54
103
376
63
166
4.65
22.71
11.7
8.0
—
—
—
0
0
127
547
3.51
22.60
8.8
3.0
0.46
0.43
e6/l
0.09
110
418
132
585
3.48
22.39
6.8
3.8
—
—
—
0
0
126
548
3.45
21.94
3.5
2.1
—
—
—
0
0
161
816
3.44
21.76
3.8
2.4
—
—
—
0
0
85
292
3.80
21.25
6.6
2.7
0.80
0.83
mmol/l
1.54
78
264
120
520
3.37
20.80
9.0
2.9
—
—
—
0
0
44
94
5.40
20.21
3.4
1.4
9.45
2.76
ug/l
1.35
33
72
103
414
3.42
20.06
3.2
2.1
—
—
—
0
0
102
408
3.42
20.01
6.0
2.8
516.78
552.57
mosm/kgh2o
1.05
96
340
141
701
3.13
18.93
9.8
3.6
389.23
101.24
e6/l
0.82
117
506
77
266
3.66
18.86
7.8
5.0
1.07
1.01
mmol/l
0.73
72
241
80
316
3.18
15.52
9.0
2.9
1.34
1.79
e6/l
0.31
56
185
56
188
3.50
14.03
10.3
6.8
13.30
11.91
mmol/l
0.45
51
179
59
208
3.35
13.66
6.3
3.7
5.88
5.79
kpa
0.30
59
199
59
209
3.34
13.55
6.3
3.7
1.45
1.88
mmol/l
0.39
51
172
93
439
2.71
12.71
5.7
3.2
86.10
82.46
%
0.72
93
427
38
107
3.97
12.23
12.7
9.4
—
—
—
0
0
147
877
2.50
12.18
11.3
5.3
1.21
1.21
mmol/l
0.01
136
762
158
977
2.50
12.07
14.7
5.3
4.97
4.57
e9/l
0.84
136
851
141
828
2.48
12.05
8.7
3.4
32.31
35.03
g/l
5.82
132
757
65
272
2.83
11.04
9.5
6.2
-0.92
1.39
mmol/l
5.07
53
212
43
142
3.42
10.93
2.2
1.8
0.21
0.20
g/l
0.53
35
121
151
953
2.34
10.49
12.0
5.8
1.20
1.21
mmol/l
0.22
129
805
197
1423
2.45
9.64
12.8
4.9
92.48
77.36
u/l
1.39
188
1286
186
1321
2.33
9.29
9.0
4.1
—
—
—
0
0
100
554
2.28
9.18
7.5
3.2
7.38
7.40
ph
2.26
22
89
155
1044
2.15
8.53
17.8
18.3
1.40
1.45
inr
0.22
38
297
127
805
2.10
8.06
6.8
5.1
8.95
8.90
%
0.06
115
739
107
636
2.14
8.04
7.1
2.0
2.35
2.34
mmol/l
0.22
96
513
76
399
2.26
7.75
12.8
4.2
—
—
—
0
0
13
11
12.35
7.66
1.2
1.2
—
—
—
0
0
125
799
2.06
7.65
6.7
4.9
2.97
3.05
%
0.12
112
734
127
819
2.05
7.56
6.8
5.1
19.39
25.22
%
7.61
115
753
122
776
2.05
7.54
6.8
4.8
0.56
0.62
%
0.53
110
713
125
810
2.02
7.27
6.6
4.9
64.38
59.04
%
4.28
113
749
133
891
1.98
6.94
8.0
5.3
0.00
0.00
estimate
-0.00
32
142
133
895
1.96
6.82
5.9
3.9
0.00
0.00
estimate
-0.00
37
162
121
789
1.97
6.79
6.8
5.1
—
—
—
0
0
132
899
1.92
6.41
7.2
4.8
0.21
0.22
e9/l
0.18
110
779
132
908
1.89
6.14
5.9
3.9
0.00
0.00
estimate
-0.00
35
138
39
172
2.48
5.80
6.2
3.8
4.92
5.13
kpa
0.98
39
166
126
866
1.86
5.77
7.0
4.6
0.68
0.63
e9/l
1.02
102
747
126
869
1.85
5.69
6.9
4.6
0.04
0.04
e9/l
0.42
102
753
38
170
2.44
5.48
6.2
3.9
7.41
7.41
ph
—
8
21
21
68
3.27
5.47
1.1
1.4
—
—
—
0
0
54
282
2.15
5.43
3.0
1.8
—
—
—
0
0
126
884
1.80
5.26
7.1
4.7
1.51
1.79
e9/l
3.43
105
777
11
15
7.59
5.19
1.1
1.1
—
—
—
0
0
26
100
2.77
5.06
1.5
1.6
1.99
1.57
g/l
1.00
20
89
21
73
3.04
4.88
2.5
1.7
—
—
—
0
0
72
437
1.89
4.72
5.4
3.9
—
—
—
0
0
51
276
2.05
4.65
3.4
2.5
18.55
23.55
%
2.59
44
242
19
67
2.98
4.32
2.5
2.2
0.30
0.29
g/l
0.03
13
19
21
79
2.80
4.27
2.4
1.8
2.58
3.21
ug/l
0.09
16
65
31
144
2.30
4.12
1.3
1.4
—
—
—
0
0
11
22
5.17
4.05
3.1
1.4
42.40
57.66
u/ml
0.14
11
22
103
723
1.69
4.04
5.9
3.6
6.10
5.87
ph
—
5
39
35
173
2.18
4.02
4.4
3.2
4.78
4.57
kpa
0.23
35
163
23
94
2.58
4.00
7.2
4.9
23.84
24.86
mmol/l
1.13
23
88
36
182
2.13
3.91
5.4
3.2
—
—
—
0
0
27
121
2.37
3.89
6.3
4.1
—
—
—
0
0
14
44
3.30
3.83
4.2
3.3
—
—
—
0
0
82
550
1.71
3.76
2.6
2.1
3.16
2.89
mg/l
0.57
62
457
108
782
1.64
3.68
14.8
8.4
0.00
0.00
e9/l
0.51
83
638
212
1851
1.70
3.09
33.5
14.2
41.28
26.86
mg/l
6.43
198
1439
62
407
1.68
3.02
5.7
2.0
2.49
2.43
mmol/l
2.37
54
332
72
495
1.62
2.93
6.5
4.1
0.00
0.00
estimate
-0.00
24
139
5
7
7.25
2.56
1.4
1.0
3.48
5.96
nmol/l
—
5
7
67
472
1.56
2.43
5.7
3.5
—
—
—
0
0
39
240
1.73
2.39
1.1
1.2
—
—
—
0
0
22
112
2.05
2.38
3.5
3.7
0.30
0.09
%
—
10
34
30
171
1.85
2.36
1.7
1.6
65.61
66.50
g/l
0.27
24
149
24
127
1.98
2.35
1.3
1.4
—
—
—
0
0
23
121
1.99
2.29
3.4
3.6
1.09
0.80
%
0.24
11
43
73
532
1.51
2.26
3.9
2.6
402.92
9076.72
umol/l
2.73
62
450
27
152
1.86
2.22
6.2
3.6
—
—
—
0
0
20
103
2.02
2.11
3.8
3.9
1.75
0.64
%
—
8
36
10
37
2.77
2.09
5.1
2.8
65.10
65.45
%
—
10
37
55
383
1.55
2.09
1.7
1.7
2.02
1.40
mg/l
0.63
50
296
96
751
1.43
2.05
3.6
2.7
237.65
143.91
ug/l
1.07
88
679
112
901
1.42
2.05
4.9
4.2
36.25
52.59
ng/l
1.31
101
694
8
28
2.91
1.87
1.1
1.1
—
—
—
0
0
11
46
2.45
1.87
4.1
3.3
—
—
—
0
0
35
226
1.63
1.82
2.1
1.8
—
—
—
0
0
28
173
1.69
1.72
1.4
1.6
—
—
—
0
0
5
13
3.90
1.72
1.0
1.2
7.90
286.98
u/ml
—
5
13
7
25
2.85
1.66
1.0
1.3
—
—
—
0
0
112
927
1.36
1.65
2.3
2.1
92.45
91.68
pmol/l
0.06
81
487
19
107
1.83
1.59
3.8
3.7
0.00
0.07
%
—
7
30
32
210
1.59
1.57
2.0
2.0
65.41
64.33
e9/l
0.06
24
166
40
278
1.52
1.54
1.8
1.9
1.84
1.65
%
0.43
33
247
5
15
3.38
1.53
1.0
1.0
—
—
—
0
0
11
51
2.21
1.52
3.6
2.1
—
—
—
0
0
0
44
0.00
1.52
0.0
1.8
—
—
—
0
0
7
27
2.63
1.52
1.6
2.6
64.29
60.81
%
—
7
27
9
38
2.41
1.47
2.6
1.2
—
—
—
0
0
6
22
2.77
1.44
1.3
1.4
—
—
—
0
0
27
174
1.61
1.44
7.3
5.7
23.36
24.29
mmol/l
0.64
27
167
18
104
1.78
1.41
5.2
2.8
0.62
0.64
%
0.12
18
104
7
29
2.45
1.40
1.6
1.3
—
—
—
0
0
7
29
2.45
1.40
2.0
3.2
—
—
—
0
0
7
29
2.45
1.40
2.0
3.7
—
—
—
0
0
5
17
2.98
1.36
1.2
1.9
11.86
10.96
%
—
5
17
0
37
0.00
1.35
0.0
1.2
—
—
—
0
0
27
177
1.58
1.35
1.3
1.3
—
—
—
0
0
29
194
1.55
1.34
5.3
3.4
—
—
—
0
0
20
123
1.68
1.28
7.1
3.2
—
—
—
0
0
8
36
2.26
1.25
1.1
1.2
—
—
—
0
0
6
25
2.43
1.25
1.2
1.2
—
—
—
0
0
61
478
1.36
1.25
1.9
1.8
1036.43
1155.35
nmol/l
0.39
46
373
211
1966
1.34
1.18
15.5
8.9
23.91
25.24
u/l
0.60
202
1856
57
447
1.35
1.16
5.9
4.0
74.97
345.57
ng/l
2.21
49
386
214
2004
1.34
1.11
41.6
17.7
138.74
139.80
mmol/l
5.75
208
1927
214
2005
1.33
1.09
42.0
17.8
4.08
4.03
mmol/l
2.02
207
1930
9
47
1.95
1.03
1.1
1.1
—
—
—
0
0
42
538
0.74
1.00
3.8
3.5
—
—
—
0
0
216
2038
1.31
0.96
48.5
20.6
91.51
91.68
fl
0.19
210
1982
216
2038
1.31
0.96
48.6
20.7
246.23
233.85
e9/l
1.70
207
1961
216
2039
1.31
0.95
48.9
20.8
123.37
135.63
g/l
18.65
211
1982
216
2039
1.31
0.95
50.2
20.8
37.03
39.81
%
8.28
206
1854
216
2039
1.31
0.95
48.4
20.6
30.21
30.52
pg
1.59
210
1983
216
2039
1.31
0.95
48.6
20.7
4.18
4.47
e12/l
10.63
204
1945
216
2040
1.30
0.94
48.5
20.6
7.47
6.97
e9/l
2.87
204
1949
19
276
0.66
0.93
1.1
1.3
25.00
38.27
iu/ml
—
6
85
176
1883
0.81
0.87
5.1
5.5
2.42
2.50
mmol/l
0.63
155
1688
162
1747
0.82
0.86
4.3
4.4
1.36
1.26
mmol/l
1.11
139
1550
168
1805
0.81
0.86
4.6
4.9
1.35
1.39
mmol/l
0.65
148
1614
127
1139
1.22
0.85
5.1
4.1
4.99
2.14
ug/l
0.96
105
993
10
57
1.78
0.85
4.0
2.7
—
—
—
0
0
24
172
1.43
0.84
6.0
3.9
—
—
—
0
0
55
450
1.28
0.84
1.4
1.3
—
—
—
0
0
169
1811
0.82
0.82
8.0
6.8
42.48
41.44
mmol/mol
0.59
148
1637
203
1915
1.25
0.81
30.7
13.7
—
—
—
0
0
12
74
1.65
0.79
1.1
1.2
—
—
—
0
0
171
1824
0.83
0.75
4.6
4.9
4.27
4.31
mmol/l
0.21
150
1650
6
108
0.55
0.74
1.0
1.3
—
—
—
0
0
22
295
0.72
0.72
2.0
1.2
2.56
2.97
g/l
0.31
11
170
65
554
1.23
0.71
1.7
1.6
19.15
20.07
nmol/l
0.18
54
463
7
41
1.73
0.70
2.3
3.0
—
—
—
0
0
5
27
1.87
0.69
1.6
1.9
3.56
5.23
e9/l
—
5
27
149
1383
1.17
0.63
5.1
4.3
—
—
—
0
0
12
80
1.52
0.61
1.2
1.3
—
—
—
0
0
0
20
0.00
0.60
0.0
1.0
—
278.86
—
0
14
19
140
1.38
0.60
2.0
1.3
—
—
—
0
0
142
1319
1.16
0.58
4.9
3.5
15.29
15.05
pmol/l
0.52
121
1153
27
213
1.30
0.56
2.0
1.4
—
—
—
0
0
74
660
1.17
0.50
5.4
4.4
—
—
—
0
0
18
137
1.34
0.48
1.8
2.2
9.25
14.90
nmol/l
2.29
13
114
41
479
0.83
0.48
1.8
1.7
1.29
1.31
mmol/l
0.08
34
380
68
606
1.16
0.47
2.8
2.8
1.08
0.78
ug/l
0.32
52
428
14
185
0.74
0.44
1.8
1.5
—
—
—
0
0
14
104
1.37
0.44
6.7
3.7
—
—
—
0
0
8
58
1.39
0.42
4.7
3.4
—
—
—
0
0
0
17
0.00
0.41
0.0
1.2
—
—
—
0
0
5
35
1.44
0.39
1.2
1.2
14.88
23.50
u/l
—
5
28
5
35
1.44
0.39
1.2
1.1
—
—
—
0
0
9
69
1.31
0.37
11.9
3.5
—
—
—
0
0
16
127
1.28
0.34
1.9
1.6
—
—
—
0
0
77
712
1.11
0.31
3.2
3.2
6.95
7.65
mmol/l
0.88
67
580
7
53
1.33
0.31
1.6
3.1
0.80
0.95
nmol/l
—
7
38
81
754
1.11
0.29
3.7
3.9
18.78
8.97
mg/mmol
0.93
66
478
76
706
1.11
0.28
3.4
3.3
116.42
244.12
mg/l
0.48
61
456
145
1392
1.09
0.27
4.6
4.1
20.22
13.24
mm/h
3.60
136
1239
5
75
0.66
0.26
1.4
1.4
—
—
—
0
0
47
427
1.12
0.26
6.8
4.4
1.02
1.02
kg/l
—
6
69
16
134
1.21
0.23
1.9
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
147.73
—
0
11
0
11
0.00
0.21
0.0
1.3
—
0.99
—
0
11
0
11
0.00
0.21
0.0
1.1
—
150.64
—
0
11
0
10
0.00
0.21
0.0
1.3
—
1.51
—
0
10
0
12
0.00
0.21
0.0
1.3
—
156.94
—
0
12
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
15
127
1.19
0.20
2.9
2.4
—
—
—
0
0
181
1850
0.93
0.18
5.4
5.1
6.28
6.18
mmol/l
0.35
156
1632
29
319
0.90
0.17
1.3
1.2
1.12
1.40
u/ml
—
6
87
17
148
1.16
0.17
3.0
3.0
—
—
—
0
0
7
90
0.77
0.14
5.0
2.5
860.57
433.03
ug/l
—
7
82
10
115
0.86
0.11
1.2
1.2
—
—
—
0
0
11
97
1.14
0.09
1.1
1.3
—
27.60
—
0
8
5
64
0.78
0.08
1.4
1.3
—
—
—
0
0
169
1710
0.97
0.07
5.8
4.3
2.04
2.00
mu/l
0.16
147
1495
50
490
1.03
0.02
2.0
1.8
325641364.38
414.67
pmol/l
0.49
39
394
5
52
0.96
0.00
1.4
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
29.20
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
5.5
—
—
—
0
0
5
57
0.87
-0.00
4.2
3.5
7.43
7.42
ph
—
5
48
0
5
0.00
-0.00
0.0
1.0
—
2975.20
—
0
5
0
7
0.00
-0.00
0.0
1.1
—
12.79
—
0
7
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
54.29
—
0
7
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
60
1.00
-0.00
1.8
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.8
—
46.00
—
0
6
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: C3_URINARY_TRACT_NAS_WIDE – Malignant neoplasm of other and unspecified urinary organs, including Hilmo

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).