Ectropion of eyelid

H7_ECTROPION

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H02.1
  • Hospital discharge: ICD-9 3741
  • Hospital discharge: ICD-8 37811
  • Cause of death: ICD-10 H02.1
  • Cause of death: ICD-9 3741
  • Cause of death: ICD-8 37811

2 out of 7 registries used, show all original rules.

1482

4. Check minimum number of events

None

1482

5. Include endpoints

None

1482

6. Filter based on genotype QC (FinnGen only)

1482

Control definitions (FinnGen only)

Control exclude
H7_LIDLACRIMALORBIT

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H02
Name in latin
Ectropium (palpebrae)

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 12729 5446 7166
Only index persons 10216 4586 5630
Unadjusted period prevalence (%)
Whole population 0.18 0.16 0.20
Only index persons 0.19 0.17 0.21
Median age at first event (years)
Whole population 77.77 79.83 76.20
Only index persons 77.93 79.92 76.30

-FinnGen-

Key figures

All Female Male
Number of individuals 1482 486 996
Unadjusted period prevalence (%) 0.35 0.17 0.44
Median age at first event (years) 76.16 76.27 76.11

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1318
Matched controls
13180
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H02.1
ICD-10 Finland
Ectropion of eyelid
4503599627370496.0
323.0
1272
5
CBN30
NOMESCO Finland
Shortening of canthal ligament
2585.1
243.3
228
*
CBF99
NOMESCO Finland
Other operation for ectropion
2445.5
232.2
218
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
6.6
217.3
926
3460
H02.3
ICD-10 Finland
Blepharochalasis
333.0
200.1
198
7
CBF10
NOMESCO Finland
Shortening of canthal ligaments and tarsal plate for ectropion
+∞
194.7
182
*
H02.0
ICD-10 Finland
Entropion and trichiasis of eyelid
380.5
167.2
165
5
CBF20
NOMESCO Finland
Resection of part of tarsus for ectropion
1692.1
155.3
148
*
CBN99
NOMESCO Finland
Other operation on eyelid for malposition
+∞
140.1
132
*
H04.10
ICD-10 Finland
Dry eye syndrome
15.2
119.9
206
158
H02.4
ICD-10 Finland
Ptosis of eyelid
159.3
98.6
103
7
XCC00
NOMESCO Finland
Investigative irrigation of lacrimal passages
264.2
97.0
98
*
CBB10
NOMESCO Finland
Excision of redundant skin of eyelid
508.4
96.7
95
*
H04.5
ICD-10 Finland
Stenosis and insufficiency of lacrimal passages
261.3
96.0
97
*
H02.2
ICD-10 Finland
Lagophthalmos
871.5
84.5
82
*
WX110
NOMESCO Finland
Local anesthesy
3.1
82.3
860
4952
CBF30
NOMESCO Finland
Excision of tarsus and skin for ectropion
826.1
80.3
78
*
CBN20
NOMESCO Finland
Shortening of eyelid retractors
399.5
76.6
76
*
H01.0
ICD-10 Finland
Blepharitis
14.9
75.4
129
95
CBN50
NOMESCO Finland
Excision of tarsus and skin
+∞
72.6
69
*
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
2.8
67.8
712
3898
ZXA10
NOMESCO Finland
Bilateral
3.2
62.4
400
1563
S18
ICPC
Laceration/cut
2.5
55.0
646
3615
CBB11
NOMESCO Finland
Resection of lax skin in upper eyelid
93.8
49.2
54
6
TQW40
NOMESCO Finland
Remowal of suture of skin
5.0
45.4
157
350
TCC10
NOMESCO Finland
Probing of lacrimal canaliculus/duct
162.2
45.1
47
*
ZXA05
NOMESCO Finland
Left side
2.5
44.0
467
2394
ZXA00
NOMESCO Finland
Right side
2.4
43.0
483
2540
CBB20
NOMESCO Finland
Correction of lax skin of eyelid and resection of herniated fat
221.9
42.1
43
*
WX002
NOMESCO Finland
Sedation and analgesia
2.7
40.0
333
1478
SPAT1153
SPAT
Removal of sutures
2.3
38.4
483
2652
H04.2
ICD-10 Finland
Epiphora
388.0
38.2
38
*
H10.0
ICD-10 Finland
Mucopurulent conjunctivitis
6.1
38.2
109
193
3741A
ICD-9 Finland
Other disorders of eyelids, Ectropion
+∞
36.6
35
*
J01DB01
ATC
cefalexin; oral
2.2
35.7
998
7688
CBB30
NOMESCO Finland
Excision of lesion of eyelid
6.9
33.7
86
131
H00.1
ICD-10 Finland
Chalazion
16.5
33.5
54
34
CCA20
NOMESCO Finland
Incision of lacrimal punctum or canaliculus
+∞
33.5
32
*
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
2.0
33.3
684
4565
G51.0
ICD-10 Finland
Bell palsy
7.3
32.9
81
117
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
3.0
32.3
213
807
F29
ICPC
Eye symptom/complaint other
4.0
32.3
138
375
S01GX01
ATC
cromoglicic acid; ophthalmic
3.0
32.1
203
747
CBK11
NOMESCO Finland
Operation for lagophtalmus with implant
169.0
31.8
33
*
N02BE01
ATC
paracetamol; systemic, rectal
2.2
30.0
1088
8938
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
5.4
29.6
92
181
37811
ICD-8 Finland
Other diseases of eye, Ectropion palpebrae
+∞
29.3
28
*
E0000UV
ATC
NA
2.0
28.2
488
2981
A98
ICPC
Health maint/preventive medicine
2.1
28.1
1066
8748
CBN40
NOMESCO Finland
Excision of tarsus
287.1
27.8
28
*
H25.1
ICD-10 Finland
Senile nuclear cataract
1.9
26.1
568
3750
TCC30
NOMESCO Finland
Intubation of lacrimal canaliculus/duct
265.4
25.8
26
*
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
5.3
24.9
78
155
CBH25
NOMESCO Finland
Tarsorrhaphy
254.6
24.7
25
*
CBJ50
NOMESCO Finland
Operation for ptosis of eyebrow
254.6
24.7
25
*
F03
ICPC
Eye discharge
4.5
24.3
88
204
H16.0
ICD-10 Finland
Corneal ulcer
5.3
24.2
76
151
CBJ40
NOMESCO Finland
Resection of levator muscle of eyelid
+∞
24.0
23
*
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.5
23.7
198
856
L57.0
ICD-10 Finland
Actinic keratosis
2.4
23.2
221
1024
CBB00
NOMESCO Finland
Excision of chalazion
63.6
21.9
25
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.3
21.8
230
1118
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
2.7
21.4
159
642
CBA10
NOMESCO Finland
Biopsy of eyelid
10.5
21.2
41
40
XCK10
NOMESCO Finland
Photography of fundus of eye
2.4
21.0
188
842
H10.5
ICD-10 Finland
Blepharoconjunctivitis
14.3
20.9
35
25
CBE20
NOMESCO Finland
Shortening of eyelid retractors for entropion
+∞
20.9
20
*
CBH10
NOMESCO Finland
Plactic repair of canthus
213.1
20.6
21
*
D23.1
ICD-10 Finland
Benign neoplasm: Skin of eyelid, including canthus
4.4
20.4
76
182
S01AA01
ATC
chloramphenicol; ophthalmic (antibiotics)
3.6
20.3
96
284
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.5
20.0
171
747
CBN00
NOMESCO Finland
Eversion suture of eyelid
202.8
19.6
20
*
H10
ICD-10 Finland
Conjunctivitis
4.4
19.4
72
172
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
5.8
19.3
55
98
F16
ICPC
Eyelid symptom/complaint
4.1
19.2
76
193
WX408
NOMESCO Finland
General anesthesy, balanced
1.9
19.2
334
1985
QAE40
NOMESCO Finland
Repair of anomaly or lesion after disease of skin of head or neck
34.9
18.9
24
7
D07AB02
ATC
hydrocortisone butyrate; topical
1.9
18.9
349
2117
QAJ10
NOMESCO Finland
Browlift
+∞
18.8
18
*
CBJ30
NOMESCO Finland
Plastic repair of levator aponeurosis of eyelid
+∞
18.8
18
*
CBB50
NOMESCO Finland
Excision of lesion of eyelid and reconstruction using graft or flap
17.4
18.7
29
17
C44.11
ICD-10 Finland
Basocellular carcinoma of the skin of the eyelids including the corner of the eye
7.4
18.6
44
61
CBD99
NOMESCO Finland
Other plastic reconstruction of eyelid
192.5
18.6
19
*
WX100
NOMESCO Finland
Conjunctival surface anesthesia
2.2
18.5
215
1086
H01.80
ICD-10 Finland
Prolonged inflammation in the edge of the eyelid
53.2
18.0
21
*
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.8
17.8
362
2264
CBG99
NOMESCO Finland
Other operation for trichiasis
+∞
17.7
17
*
ZZA50
NOMESCO Finland
Full thickness skin graft
9.0
17.2
36
41
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.7
17.2
611
4511
Z96.1
ICD-10 Finland
Presence of intraocular lens
1.9
17.0
276
1591
SAA01
NOMESCO Finland
Simple examination of mouth
1.6
16.9
625
4655
QA4S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in face
20.3
16.4
24
12
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
2.8
16.0
106
398
QAJ30
NOMESCO Finland
Other facelift
33.8
15.7
20
6
H02AB06
ATC
prednisolone; systemic
1.6
15.5
601
4493
CBH30
NOMESCO Finland
Tarsorraphy
161.7
15.5
16
*
ZZC00
NOMESCO Finland
Graft of fascia
45.5
15.1
18
*
H10.4
ICD-10 Finland
Chronic conjunctivitis
18.6
14.7
22
12
CB9S4
NOMESCO Finland
Photography of eyelids and eyebrows
25.3
14.7
20
8
CBE40
NOMESCO Finland
Combined correction of entropion
+∞
14.6
14
*
CBG00
NOMESCO Finland
Epilation of cilia by electrolysis
+∞
14.6
14
*
TQW99
NOMESCO Finland
Other minor procedure on skin
2.8
14.5
97
367
CBD10
NOMESCO Finland
Plastic reconstruction of eyelid using graft or flap
151.5
14.5
15
*
K02.1
ICD-10 Finland
Caries of dentine
1.6
14.1
479
3434
QAE20
NOMESCO Finland
Excision and repair of scar or web of skin of head or neck
15.9
13.9
22
14
H00.00
ICD-10 Finland
Hordeolum
5.9
13.8
38
66
CCD60
NOMESCO Finland
Transnasal dacryocystorhinostomy
+∞
13.6
13
*
H04.4
ICD-10 Finland
Chronic inflammation of lacrimal passages
+∞
13.6
13
*
CBC00
NOMESCO Finland
Suturation or/and revision of eyelid
34.4
13.5
17
5
C44.10
ICD-10 Finland
Malignant tumor of the skin of the eyelids including the corner of the eye without histology
10.2
13.5
26
26
E85.80
ICD-10 Finland
Meretoja sick
141.3
13.5
14
*
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.8
13.1
232
1367
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.9
12.5
187
1039
S29
ICPC
Skin symptom/complaint other
1.9
12.5
208
1201
A28
ICPC
Limited function/disability NOS
1.7
12.3
305
1993
D07AC01
ATC
betamethasone; topical
1.6
12.2
407
2881
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
2.2
12.0
127
611
I10
ICD-10 Finland
Essential (primary) hypertension
1.5
12.0
851
7160
A02BC02
ATC
pantoprazole; systemic
1.5
12.0
763
6266
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
3.4
11.8
57
174
AA1AD
NOMESCO Finland
CT of head and brain
1.6
11.8
354
2436
H26.4
ICD-10 Finland
After-cataract
1.9
11.6
187
1063
N06AX11
ATC
mirtazapine; oral
1.6
11.5
338
2310
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.6
11.5
412
2960
CCD50
NOMESCO Finland
Dacryocystorhinostomy with insertion of tube
+∞
11.5
11
*
3231
FHL
Abbreviation for eyelid
+∞
11.5
11
*
CBW99
NOMESCO Finland
Other operation on eyelid
+∞
11.5
11
*
CBF40
NOMESCO Finland
Plastic repair of eyelid for cicatricial ectropion
120.9
11.4
12
*
QAJ20
NOMESCO Finland
Subperiosteal facelift
120.9
11.4
12
*
EBA00
NOMESCO Finland
Extraction of tooth
1.6
11.4
326
2210
M79.6
ICD-10 Finland
Pain in limb
1.6
11.4
366
2556
S01AX11
ATC
[U] ofloxacin; ophthalmic
2.7
11.4
76
289
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.6
11.3
315
2121
R06AE07
ATC
cetirizine; oral
1.6
11.1
392
2801
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.9
11.0
179
1021
ZZR00
NOMESCO Finland
Flap of skin
3.1
10.9
59
196
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.5
10.9
449
3328
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.7
10.6
71
270
XCH00
NOMESCO Finland
Eye pressure measurement
2.8
10.6
70
263
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.5
10.6
429
3160
A29
ICPC
General symptom/complaint other
1.9
10.5
164
920
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.7
10.5
257
1668
F72
ICPC
Blepharitis/stye/chalazion
6.2
10.5
27
44
H19.8*E85.80
ICD-10 Finland
Reticular keratitis in Meretoja's patients
110.8
10.4
11
*
F02
ICPC
Red eye
3.2
10.4
53
169
H02.5
ICD-10 Finland
Other disorders affecting eyelid function
+∞
10.4
10
*
CBE99
NOMESCO Finland
Other operation for entropion
+∞
10.4
10
*
CBK99
NOMESCO Finland
Other operation for retraction of eyelid
+∞
10.4
10
*
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.5
10.4
476
3601
H16.9
ICD-10 Finland
Keratitis, unspecified
6.9
10.4
25
37
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.5
10.4
459
3444
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
2.8
10.3
64
233
ZZF00
NOMESCO Finland
Graft of adipose tissue
18.9
10.3
15
8
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
3.2
10.1
52
167
QAB10
NOMESCO Finland
Major dressing of wound of skin of head or neck
6.0
10.1
27
46
L08
ICPC
Shoulder symptom/complaint
1.8
10.1
195
1179
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.5
10.0
439
3283
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.7
10.0
205
1259
SPAT1301
SPAT
No procedures
1.5
10.0
413
3050
J01DA01
ATC
[U] cefalexin; systemic
1.5
9.9
729
6057
ZXC50
NOMESCO Finland
Cryotherapy
2.8
9.7
61
224
J05AB11
ATC
valaciclovir; oral
2.0
9.6
131
702
L03
ICPC
Low back symptom/complaint
1.7
9.6
225
1440
J01AA02
ATC
doxycycline; systemic
1.5
9.5
904
7879
CBG20
NOMESCO Finland
Plastic repair of margin of eyelid for trichiasis
100.7
9.4
10
*
S01ED51
ATC
timolol, combinations; ophthalmic
1.9
9.4
133
722
CBB21
NOMESCO Finland
Correction of lax skin and resection of herniated fat in upper eyelid
+∞
9.4
9
*
8090/3-C44.1
ICD-O-3
Basal cell carcinoma, NOS, of eyelid
5.9
9.4
25
43
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
2.6
9.2
67
270
H81
ICPC
Excessive ear wax
1.6
9.2
240
1578
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.7
9.2
190
1172
J05AB01
ATC
aciclovir; systemic
1.7
9.1
199
1247
S01.1
ICD-10 Finland
Open wound of eyelid and periocular area
3.5
9.1
41
120
J01CE02
ATC
phenoxymethylpenicillin; oral
1.4
9.1
672
5550
CG2S4
NOMESCO Finland
Photography of cornea
11.5
9.1
16
14
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.9
9.0
139
781
CFA20
NOMESCO Finland
Biopsy of conjunctiva
18.7
8.9
13
7
E000001
ATC
NA
1.6
8.9
223
1452
SPAT1234
SPAT
Support of social functional capacity
2.1
8.9
99
490
R5140
NOMESCO Finland
Monitoring the use of the aid
2.0
8.9
113
588
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.5
8.9
336
2419
L17
ICPC
Foot/toe symptom/complaint
1.6
8.8
270
1852
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.6
8.8
230
1512
S01EE05
ATC
tafluprost; ophthalmic
2.8
8.7
55
202
CD2S4
NOMESCO Finland
Photography of eye
14.1
8.7
14
10
N05CF01
ATC
zopiclone; oral
1.5
8.7
440
3368
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
1.9
8.7
118
633
D07AB08
ATC
desonide; topical
1.9
8.6
123
669
SAA02
NOMESCO Finland
Basic examination of mouth
1.4
8.6
500
3930
WX199
NOMESCO Finland
Other local analgesia
3.1
8.6
46
154
ELB50
NOMESCO Finland
Total parotidectomy
16.4
8.6
13
8
317
Kela drug reimbursment
Topical pimecrolimus and tacrolimus
9.0
8.5
17
19
H10.2
ICD-10 Finland
Other acute conjunctivitis
9.0
8.5
17
19
L82
ICD-10 Finland
Seborrhoeic keratosis
1.7
8.5
174
1066
S01XA18
ATC
ciclosporin; ophthalmic
20.1
8.5
12
6
J01CA04
ATC
amoxicillin; systemic
1.4
8.5
832
7202
H13
ICPC
Plugged feeling ear
1.6
8.5
240
1612
S97
ICPC
Chronic ulcer skin
2.1
8.5
96
480
CBH99
NOMESCO Finland
Other operation on canthus
90.6
8.4
9
*
UKC02
NOMESCO Finland
Cystoscopy
1.6
8.4
273
1896
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.9
8.4
125
694
CBK10
NOMESCO Finland
Operation for lagophtalmus
+∞
8.3
8
*
3232
FHL
Eyelid shortening and skin plastic
+∞
8.3
8
*
CBE10
NOMESCO Finland
Orbicularis muscle operation for entropion
+∞
8.3
8
*
SPAT1101
SPAT
Orthostatic test
2.1
8.3
90
440
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
3.1
8.3
44
147
SPAT1254
SPAT
Administration of medicine
1.6
8.2
224
1489
L28
ICPC
Limited function/disability (L)
1.6
8.1
252
1728
H10.1
ICD-10 Finland
Acute atopic conjunctivitis
4.9
8.1
25
52
CG2T4
NOMESCO Finland
Topography assessment of cornea
6.9
8.1
19
28
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.6
8.1
223
1486
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.4
8.1
405
3087
S01AD03
ATC
aciclovir; ophthalmic
2.9
8.0
46
160
H57.1
ICD-10 Finland
Ocular pain
4.6
8.0
26
57
D07AA02
ATC
hydrocortisone; topical
1.8
8.0
148
883
N03AX12
ATC
gabapentin; oral
1.8
7.9
151
906
SPAT1053
SPAT
Memory test
1.5
7.9
275
1940
XCK00
NOMESCO Finland
Perimetry
2.0
7.9
95
484
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.5
7.8
349
2595
SPAT1263
SPAT
Sampling
1.4
7.8
481
3805
D33.30
ICD-10 Finland
Acoustic neuroma
9.5
7.8
15
16
X59
ICD-10 Finland
Exposure to unspecified factor
1.7
7.8
180
1144
H18.5
ICD-10 Finland
Hereditary corneal dystrophies
7.0
7.8
18
26
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.6
7.8
217
1448
SPAT1325
SPAT
Vaccination
1.4
7.8
458
3595
R02
ICPC
Shortness of breath/dyspnoea
1.7
7.7
151
915
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.5
7.7
292
2096
J01FF01
ATC
clindamycin; systemic
1.5
7.7
284
2025
SAA03
NOMESCO Finland
Extended examination of mouth
1.5
7.7
297
2139
R01AD08
ATC
fluticasone; nasal
1.6
7.7
233
1590
B01AB05
ATC
enoxaparin; parenteral
1.4
7.6
369
2789
CAC10
NOMESCO Finland
Reconstruction of orbital wall using bone graft or plate
18.5
7.6
11
6
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.6
7.6
235
1608
M25.5
ICD-10 Finland
Pain in joint
1.6
7.6
225
1524
S15
ICPC
Foreign body in skin
2.3
7.5
70
320
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.7
7.5
170
1075
K85
ICPC
Elevated blood pressure
1.6
7.5
191
1246
S01GX08
ATC
ketotifen; ophthalmic
3.4
7.4
34
102
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
2.3
7.4
65
290
WX320
NOMESCO Finland
Spinalanesthesy
1.5
7.4
266
1884
H05.2
ICD-10 Finland
Exophthalmic conditions
80.5
7.4
8
*
R13
ICD-10 Finland
Dysphagia
2.0
7.4
88
449
KMAK
NOMESCO Finland
NA
1.4
7.4
407
3145
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
4.4
7.3
25
58
S01GX02
ATC
levocabastine; ophthalmic
2.6
7.3
51
201
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
2.2
7.3
74
353
CBN60
NOMESCO Finland
Excision of scar of eyelid and plastic reconstruction
+∞
7.3
7
*
H06.2*E05.9
ICD-10 Finland
Dysthyroid exophthalmos
+∞
7.3
7
*
CJB10
NOMESCO Finland
Laser discission of secondary cataract
1.7
7.3
150
920
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
2.5
7.3
55
228
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.8
7.3
130
765
Z02.4
ICD-10 Finland
Examination for driving licence
1.5
7.3
330
2454
H02AB07
ATC
prednisone; oral
1.6
7.3
193
1272
S02.30
ICD-10 Finland
Fracture of orbital floor, closed
6.3
7.2
18
29
114
Kela drug reimbursment
Glaucoma
1.7
7.2
156
972
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.6
7.2
218
1485
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
7.2
436
3429
R07.4
ICD-10 Finland
Chest pain, unspecified
1.5
7.2
325
2418
SPA47
NOMESCO Finland
Precision impression for denture
4.4
7.2
24
55
L12
ICPC
Hand/finger symptom/complaint
1.8
7.1
124
726
M48.0
ICD-10 Finland
Spinal stenosis
1.6
7.1
172
1105
S06.0
ICD-10 Finland
Concussion
1.8
7.1
118
677
S04
ICPC
Lump/swelling localized
2.0
7.1
90
471
S21
ICPC
Skin texture symptom/complaint
1.7
7.1
135
810
L20.0
ICD-10 Finland
Besnier prurigo
3.0
7.1
38
129
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
2.0
7.1
85
434
C08CA01
ATC
amlodipine; oral
1.4
7.1
505
4083
P01AB01
ATC
metronidazole; oral, rectal
1.4
7.0
363
2768
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.5
7.0
259
1846
R01AD09
ATC
mometasone; nasal
1.4
7.0
355
2695
R4110
NOMESCO Finland
Physiotherapy
1.5
6.9
284
2066
M54.5
ICD-10 Finland
Low back pain
1.5
6.9
284
2066
H20.1
ICD-10 Finland
Chronic iridocyclitis
6.4
6.9
17
27
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prothetic work
2.3
6.9
58
253
SPAT1249
SPAT
Treatment-related counselling outside office
1.4
6.9
408
3187
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.5
6.9
310
2300
SPAT1014
SPAT
Treatment of eyes
3.0
6.9
37
126
S01BA01
ATC
dexamethasone; ophthalmic (corticosteroids, plain)
2.5
6.8
52
217
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.6
6.8
194
1299
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
2.0
6.8
83
426
N03AX16
ATC
pregabalin; oral
1.5
6.8
240
1693
S86
ICPC
Dermatitis seborrhoeic
11.0
6.8
12
11
CBB99
NOMESCO Finland
Other excision or destruction of lesion of eyelid
11.0
6.8
12
11
ZXC20
NOMESCO Finland
Use of chemical agents
2.7
6.8
44
167
H11.0
ICD-10 Finland
Pterygium
5.3
6.8
19
36
SPAT1310
SPAT
Counselling related to known health issue
1.4
6.8
325
2442
D04.2
ICD-10 Finland
Carcinoma in situ: Skin of ear and external auricular canal
5.7
6.8
18
32
M54.2
ICD-10 Finland
Cervicalgia
2.2
6.8
63
291
S01.0
ICD-10 Finland
Open wound of scalp
1.8
6.8
108
614
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.4
6.7
370
2852
H91.1
ICD-10 Finland
Presbycusis
1.7
6.7
127
760
N17
ICPC
Vertigo/dizziness
1.7
6.7
137
841
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.4
6.7
425
3356
ZZA00
NOMESCO Finland
Split skin graft
2.4
6.7
53
224
D04.3
ICD-10 Finland
Carcinoma in situ: Skin of other and unspecified parts of face
2.5
6.6
48
196
TQW40
SPAT
NA
3.0
6.6
36
124
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
1.7
6.6
126
760
G47.3
ICD-10 Finland
Sleep apnoea
1.6
6.6
177
1170
C03CA01
ATC
furosemide; systemic
1.4
6.6
577
4811
P20
ICPC
Memory disturbance
1.5
6.5
222
1550
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
2.8
6.5
39
142
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
2.0
6.5
77
392
E000007
ATC
NA
2.4
6.5
52
220
R06AE09
ATC
levocetirizine; oral
1.8
6.5
106
606
R03BB04
ATC
tiotropium bromide; inhalant
1.6
6.5
172
1133
S01EC04
ATC
brinzolamide; ophthalmic
2.2
6.5
65
308
S01AX12
ATC
[U] norfloxacin; ophthalmic
6.2
6.5
16
26
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
3.1
6.4
33
109
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
2.5
6.4
49
204
T81.3
ICD-10 Finland
Disruption of operation wound, not elsewhere classified
2.9
6.4
37
130
CBH40
NOMESCO Finland
Division of tarsorrhaphy
70.1
6.4
7
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.5
6.4
270
1976
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.2
6.4
63
298
Y94.0
ICD-10 Finland
Accident at home
3.1
6.4
32
104
H04.3
ICD-10 Finland
Acute and unspecified inflammation of lacrimal passages
14.4
6.4
10
7
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.4
6.4
473
3829
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.4
6.4
448
3595
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
1.6
6.4
145
919
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
6.4
310
2333
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
1.9
6.4
84
446
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
3.2
6.4
31
99
S01GX06
ATC
emedastine; ophthalmic
6.0
6.3
16
27
C10AA01
ATC
simvastatin; oral
1.3
6.3
656
5602
H02.6
ICD-10 Finland
Xanthelasma of eyelid
+∞
6.3
6
*
TCB10
NOMESCO Finland
Simple epilation of cilia
+∞
6.3
6
*
CBH05
NOMESCO Finland
Canthopexy
+∞
6.3
6
*
H04.0
ICD-10 Finland
Dacryoadenitis
+∞
6.3
6
*
CBE00
NOMESCO Finland
Suture of eyelid for entropion
+∞
6.3
6
*
H03.1*B02.3
ICD-10 Finland
Zoster blepharitis
+∞
6.3
6
*
CBJ99
NOMESCO Finland
Other operation for ptosis
+∞
6.3
6
*
C08CA13
ATC
lercanidipine; oral
1.6
6.2
185
1250
L29
ICPC
Musculoskeletal sympt/complt other
1.9
6.2
83
443
SAA04
NOMESCO Finland
Special inverstigation of mouth
2.4
6.2
47
196
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
2.9
6.1
35
122
D31.0
ICD-10 Finland
Benign neoplasm: Conjunctiva
7.7
6.1
13
17
SDA03
NOMESCO Finland
Demanding parodonthologic therapy
1.5
6.1
253
1842
F73
ICPC
Eye infection/inflammation other
4.7
6.1
19
41
D06BX01
ATC
metronidazole; topical
1.9
6.0
89
491
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.4
6.0
313
2382
CG2X4
NOMESCO Finland
Optical coherence tomography (OCT) of cornea
6.7
6.0
14
21
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.5
6.0
205
1432

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1213
9695
2.38
36.72
22.9
18.9
30.7
29.7
mg/l
0.41
1056
8126
989
7316
2.06
36.37
5.8
5.3
507.7
2265.3
e6/l
1.18
26
153
280
1291
2.44
35.78
1.9
1.8
—
—
—
0
0
1253
10201
2.48
35.62
27.8
23.0
4.0
4.0
mmol/l
0.64
1216
9845
1251
10188
2.46
35.35
27.4
22.8
139.6
139.5
mmol/l
0.99
1215
9844
1230
9978
2.37
34.47
12.8
11.0
22.3
23.9
u/l
2.68
1172
9441
1258
10355
2.42
33.21
33.1
27.5
230.9
234.8
e9/l
1.14
1212
9965
1258
10355
2.42
33.21
33.1
27.4
92.3
91.9
fl
1.60
1227
10072
1258
10355
2.42
33.21
33.0
27.4
30.5
30.4
pg
0.27
1228
10072
1258
10356
2.42
33.18
33.2
27.5
4.3
4.3
e12/l
0.99
1210
9924
1258
10358
2.42
33.13
33.4
27.7
129.7
130.5
g/l
0.85
1230
10076
1258
10360
2.42
33.09
33.2
27.5
7.2
7.2
e9/l
0.05
1209
9926
1042
8053
1.99
31.29
8.3
7.3
83.6
83.2
u/l
0.07
973
7440
586
3770
1.92
30.73
3.0
2.3
—
—
—
0
0
1194
9745
2.16
30.09
21.2
18.5
—
—
—
0
0
799
5705
1.87
30.03
8.9
7.9
4.5
4.5
e9/l
0.11
695
4941
819
5897
1.87
29.93
7.0
6.7
1.2
1.2
mmol/l
0.23
687
4872
723
5019
1.86
29.56
5.9
5.2
0.2
0.2
e9/l
0.01
632
4316
956
7248
1.90
29.51
5.1
4.7
—
—
—
0
0
1082
8554
1.98
29.32
4.9
4.5
2.1
2.1
mu/l
0.20
943
7503
702
4870
1.84
28.38
5.7
5.0
0.0
0.0
e9/l
0.95
608
4143
698
4853
1.83
27.84
5.7
5.0
0.7
0.6
e9/l
2.21
602
4107
880
6594
1.82
27.12
5.2
4.8
6.8
7.0
mmol/l
1.73
834
6210
705
4979
1.79
26.16
5.9
5.2
1.7
1.8
e9/l
1.33
627
4299
1101
8900
1.92
26.01
7.1
6.8
41.5
41.8
mmol/mol
0.44
984
7965
1127
9191
1.94
25.78
5.5
5.1
6.1
6.2
mmol/l
0.65
983
7986
949
7340
1.81
25.64
4.6
4.0
16.1
16.1
mm/h
0.00
871
6613
1124
9169
1.94
25.54
5.6
5.2
2.4
2.4
mmol/l
1.03
1011
8072
717
5113
1.78
25.53
4.9
4.6
33.7
34.0
g/l
0.52
662
4671
741
5335
1.78
25.53
6.6
5.8
1.2
1.2
mmol/l
0.05
662
4735
665
4653
1.78
25.16
6.6
5.6
9.3
9.0
%
1.06
611
4306
662
4632
1.78
25.00
6.3
5.3
2.8
2.8
%
0.00
607
4273
671
4733
1.76
24.48
6.5
5.6
24.0
24.7
%
0.80
615
4346
646
4509
1.77
24.43
6.3
5.3
0.6
0.6
%
0.08
595
4164
778
5740
1.75
24.09
6.5
5.8
12.7
12.9
umol/l
0.14
726
5405
659
4645
1.75
23.94
6.2
5.3
60.0
59.8
%
0.12
609
4297
886
6837
1.74
22.85
3.7
3.6
15.1
15.2
pmol/l
0.25
764
5962
1083
8858
1.83
22.75
5.0
4.6
4.2
4.3
mmol/l
1.61
983
7851
567
3887
1.74
22.29
4.6
4.3
—
—
—
0
0
1069
8743
1.80
22.05
4.8
4.6
1.4
1.4
mmol/l
1.51
955
7661
514
3449
1.75
21.66
2.8
2.7
—
—
—
0
0
901
7042
1.71
21.62
4.8
4.5
—
—
—
0
0
941
7459
1.72
21.27
31.6
25.2
329.8
330.6
g/l
1.98
922
7334
1038
8472
1.75
20.92
4.4
4.1
1.3
1.2
mmol/l
0.59
924
7348
1006
8146
1.73
20.79
25.7
20.7
37.7
37.4
%
0.32
592
4663
509
3456
1.72
20.27
6.0
5.2
—
—
—
0
0
707
5242
1.67
20.17
10.5
12.3
1.4
1.4
inr
0.29
170
1412
659
4798
1.67
20.17
4.4
4.5
—
—
—
0
0
605
4308
1.68
20.15
3.3
3.3
2019.9
2300.2
ng/l
0.92
528
3763
685
5051
1.66
19.86
2.4
2.2
86.1
91.4
pmol/l
2.17
374
2675
413
2665
1.76
19.59
4.4
4.0
79.0
80.1
%
0.39
401
2584
934
7485
1.67
19.31
28.2
23.0
14.4
14.1
%
5.95
916
7275
508
3487
1.70
19.21
5.0
3.8
7.4
7.4
ph
0.17
79
673
238
1322
1.95
18.10
1.8
1.4
—
—
—
0
0
494
3431
1.66
17.52
2.4
2.3
3.1
3.2
mg/l
0.29
417
2865
543
3882
1.63
17.06
3.3
3.3
2.3
2.3
mmol/l
0.02
453
3251
580
4217
1.62
17.00
3.1
2.8
162.2
158.5
ug/l
0.09
524
3749
502
3567
1.62
15.92
2.2
2.2
204.3
252.8
u/l
0.71
468
3292
564
4132
1.59
15.68
4.4
4.0
174.1
143.8
e6/l
0.29
431
3111
480
3391
1.61
15.51
2.7
2.4
55.8
56.9
u/l
0.24
439
3103
388
2602
1.67
15.42
2.9
2.6
—
—
—
0
0
453
3161
1.62
15.37
1.6
1.6
20.2
19.4
nmol/l
0.48
393
2635
281
1727
1.77
15.33
2.6
2.2
1.8
1.8
%
0.09
241
1497
516
3735
1.59
14.93
3.9
3.5
114.8
87.4
e6/l
0.24
415
2961
410
2816
1.63
14.72
3.2
2.9
6471.9
9705.6
umol/l
0.52
348
2328
366
2444
1.66
14.69
7.6
6.2
—
—
—
0
0
553
4080
1.57
14.67
2.3
2.2
80.5
78.7
nmol/l
0.74
472
3450
389
2646
1.64
14.49
2.8
2.7
5.0
4.4
e6/l
0.52
352
2339
541
3982
1.56
14.45
4.0
3.6
—
—
—
0
0
318
2060
1.69
14.28
2.5
2.5
11.2
11.5
umol/l
0.29
287
1860
291
1848
1.72
14.04
2.9
2.8
0.8
0.8
mmol/l
0.65
266
1690
653
5034
1.53
14.02
5.3
5.6
6.8
4.1
ug/l
0.68
565
4385
294
1884
1.70
13.69
2.4
2.5
2.2
2.2
g/l
0.80
268
1696
364
2467
1.63
13.64
5.0
4.2
784.5
327.2
ng/l
0.40
327
2193
224
1343
1.79
13.16
3.7
3.2
280.1
285.7
ng/l
0.04
212
1227
279
1792
1.69
12.81
2.5
2.6
20.5
21.3
%
0.48
237
1487
259
1639
1.70
12.54
2.1
2.0
—
—
—
0
0
462
3376
1.54
12.32
3.9
3.4
0.4
0.6
e6/l
0.68
372
2632
441
3191
1.54
12.29
3.9
3.4
—
—
—
0
0
256
1633
1.69
12.00
6.2
5.1
1.1
1.0
mmol/l
0.33
228
1477
555
4249
1.49
11.71
10.9
10.5
0.0
0.0
e9/l
0.88
461
3458
344
2379
1.58
11.62
3.3
3.1
2.5
2.5
mmol/l
0.40
274
2059
94
435
2.24
11.54
1.6
1.2
—
—
—
0
0
244
1558
1.68
11.36
5.1
6.0
1.7
1.2
mmol/l
0.97
186
1184
243
1556
1.67
11.18
5.1
6.0
11.8
11.5
kpa
0.37
230
1460
243
1556
1.67
11.18
5.1
6.0
5.1
5.1
kpa
0.21
230
1461
301
2041
1.60
10.99
3.4
3.0
1.5
1.3
e6/l
0.21
176
1214
406
2952
1.52
10.84
1.8
1.9
1095.8
1188.3
nmol/l
1.33
308
2171
309
2116
1.58
10.80
33.8
32.0
1.4
1.6
inr
0.69
46
263
177
1050
1.78
10.70
2.4
2.1
0.2
0.2
g/l
0.43
154
961
193
1180
1.73
10.50
2.4
2.5
12.5
11.1
umol/l
0.22
155
1018
609
4833
1.44
10.31
4.6
4.5
55.2
62.7
ng/l
0.29
505
3870
204
1294
1.67
9.66
2.4
2.5
4.7
6.3
ug/l
1.61
174
1061
347
2530
1.49
8.90
2.9
2.9
544.3
556.8
mosm/kgh2o
0.55
295
2165
200
1295
1.63
8.71
2.6
2.4
69.0
67.9
e9/l
0.16
147
1016
441
3384
1.43
8.61
3.4
3.1
7.0
7.1
mmol/l
0.33
364
2742
209
1384
1.59
8.29
5.4
6.3
95.2
95.0
%
0.08
203
1319
614
5021
1.38
8.18
4.8
4.2
0.0
0.0
estimate
0.50
108
937
276
1953
1.51
8.12
3.6
3.2
3.3
1.8
e6/l
1.46
152
1138
434
3365
1.41
7.87
3.5
3.2
315.3
317.6
mg/l
0.00
313
2237
459
3605
1.40
7.69
4.2
3.9
10.9
10.3
mg/mmol
0.13
320
2360
177
1147
1.62
7.67
6.1
6.2
12.0
12.3
mmol/l
0.14
165
1074
266
1896
1.49
7.52
1.9
1.9
30.8
30.3
s
0.68
261
1824
118
694
1.76
7.35
1.9
1.7
1.6
1.5
g/l
0.46
100
582
228
1588
1.51
7.19
5.6
6.2
104.5
104.3
mmol/l
0.17
218
1547
600
4962
1.35
7.16
4.8
4.1
0.0
0.0
estimate
0.00
107
965
598
4943
1.35
7.16
6.2
5.6
0.0
0.0
estimate
0.00
106
945
118
706
1.73
6.93
5.6
7.6
24.8
24.4
mmol/l
0.88
107
641
175
1165
1.57
6.76
1.8
2.5
65.9
65.7
g/l
0.15
152
1023
281
2069
1.44
6.67
1.8
1.6
2.1
1.6
mg/l
0.73
224
1610
149
970
1.60
6.33
1.3
1.2
814.4
541.2
titre
0.69
36
209
170
1146
1.55
6.21
4.9
5.7
1.3
1.5
mmol/l
1.33
162
1087
75
413
1.86
5.84
1.5
2.3
36.8
36.4
g/l
0.17
61
331
145
957
1.57
5.82
4.5
3.8
119.8
103.5
ng/l
0.90
130
787
143
941
1.58
5.81
4.0
4.1
—
—
—
0
0
308
2369
1.38
5.62
5.0
4.0
—
—
—
0
0
135
885
1.58
5.58
1.5
1.4
—
—
—
0
0
357
2819
1.35
5.50
3.2
3.3
0.8
0.8
ug/l
0.17
264
2024
141
937
1.56
5.50
2.4
2.3
39.9
36.8
u/l
0.18
122
774
186
1313
1.48
5.46
1.3
1.3
—
—
—
0
0
144
964
1.55
5.44
1.7
2.4
—
—
—
0
0
158
1084
1.51
5.33
6.3
6.8
—
—
—
0
0
61
325
1.91
5.28
1.8
1.8
21.5
21.8
s
0.15
54
299
188
1339
1.46
5.27
3.6
3.8
10.7
23.0
ug/l
0.82
165
1129
155
1065
1.51
5.20
1.6
1.4
—
—
—
0
0
130
868
1.55
4.98
5.7
5.9
24.9
24.5
mmol/l
0.61
123
807
28
111
2.55
4.97
4.0
3.8
—
—
—
0
0
183
1322
1.44
4.77
3.7
3.4
1.8
2.0
mmol/l
0.38
151
1025
121
808
1.54
4.64
1.6
1.5
—
—
—
0
0
186
1362
1.42
4.50
3.5
3.5
—
7.4
—
0
7
107
702
1.57
4.45
6.7
8.2
—
—
—
0
0
47
245
1.95
4.38
1.1
1.1
1.3
1.3
u/ml
—
6
24
77
472
1.67
4.23
1.4
1.3
—
—
—
0
0
65
382
1.73
4.16
1.2
1.2
482.2
241.9
u/ml
0.80
59
347
180
1331
1.40
4.12
3.7
3.4
5.8
5.8
kpa
0.17
174
1280
61
355
1.75
4.05
3.7
3.7
—
—
—
0
0
46
246
1.90
4.01
1.6
2.4
33.2
32.9
umol/l
0.03
39
193
415
3480
1.27
3.94
4.8
4.7
—
—
—
0
0
74
464
1.63
3.75
2.4
2.5
—
17.9
—
0
11
24
102
2.38
3.75
1.2
1.1
—
—
—
0
0
166
1233
1.39
3.71
4.3
4.7
—
—
—
0
0
40
211
1.92
3.65
3.2
3.9
3.9
1.9
%
0.72
30
153
12
35
3.45
3.62
1.8
2.3
—
—
—
0
0
124
879
1.45
3.61
4.0
3.9
5.2
5.2
kpa
0.21
109
792
189
1445
1.35
3.54
1.3
1.4
2.8
2.9
g/l
0.15
102
798
122
870
1.44
3.45
4.0
3.9
7.4
7.4
ph
0.49
12
92
278
2256
1.29
3.40
5.6
4.7
1.0
1.0
kg/l
0.87
37
377
68
434
1.59
3.25
4.4
5.4
1.4
1.4
mmol/l
0.01
68
376
28
136
2.08
3.23
3.9
3.9
62.4
55.6
%
0.69
17
83
21
91
2.33
3.18
1.5
1.2
—
—
—
0
0
95
657
1.48
3.16
2.1
2.6
11.2
11.0
g/l
0.11
87
583
15
55
2.74
3.16
4.0
3.9
—
—
—
0
0
13
44
2.97
3.14
1.7
1.7
—
35.7
—
0
8
90
617
1.49
3.13
3.1
2.8
—
—
—
0
0
136
1009
1.38
3.09
4.9
3.5
—
—
—
0
0
237
1908
1.29
3.08
4.6
4.2
—
—
—
0
0
20
86
2.34
3.08
1.3
1.1
—
—
—
0
0
44
256
1.74
3.00
1.2
1.2
—
—
—
0
0
27
134
2.03
2.97
1.7
2.1
—
—
—
0
0
121
888
1.39
2.94
3.5
3.8
0.8
0.9
%
0.13
53
290
91
634
1.46
2.94
4.3
3.3
24.2
24.0
mmol/l
0.14
84
565
44
258
1.73
2.93
1.3
1.2
—
—
—
0
0
93
653
1.45
2.89
1.9
1.5
—
—
—
0
0
58
368
1.60
2.87
2.4
3.5
24.7
25.2
mmol/l
0.34
47
313
98
696
1.44
2.87
1.7
1.5
—
—
—
0
0
133
999
1.36
2.82
1.3
1.3
—
—
—
0
0
329
2790
1.23
2.73
5.7
4.4
0.0
0.0
estimate
0.50
101
886
107
781
1.40
2.70
3.6
3.8
0.6
0.6
%
0.05
35
203
76
521
1.48
2.68
1.4
1.8
1.0
1.5
g/l
1.53
66
458
7
15
4.68
2.60
1.3
1.9
99.0
133.5
ng/l
—
7
15
16
68
2.37
2.56
1.3
1.1
—
—
—
0
0
15
62
2.43
2.54
2.3
1.6
8.6
9.3
mmol/l
—
8
51
44
270
1.65
2.52
3.1
2.8
1.8
1.9
mg/l
0.27
39
231
143
1108
1.32
2.49
3.1
2.9
4.5
4.4
kpa
0.11
134
1064
33
188
1.77
2.46
2.6
2.8
—
—
—
0
0
91
658
1.41
2.45
1.7
1.5
—
—
—
0
0
94
684
1.40
2.44
1.6
1.4
—
—
—
0
0
26
138
1.90
2.42
3.0
4.4
—
—
—
0
0
153
1204
1.30
2.39
1.3
1.2
43.6
37.6
iu/ml
0.19
54
382
48
307
1.58
2.35
2.2
2.3
106.2
90.4
ug/min
0.14
26
187
96
708
1.38
2.32
2.7
3.0
0.5
0.4
e6/l
0.19
96
689
14
59
2.39
2.29
1.2
1.6
—
—
—
0
0
50
325
1.56
2.29
2.6
3.2
7.6
7.7
kpa
0.20
43
293
28
156
1.81
2.26
1.5
2.1
—
—
—
0
0
12
48
2.51
2.19
1.4
1.9
21.2
16.5
%
—
6
22
47
305
1.56
2.18
3.4
3.9
—
—
—
0
0
23
122
1.90
2.16
1.0
1.1
—
—
—
0
0
192
1579
1.25
2.12
1.2
1.2
1.7
1.7
u/ml
0.01
43
380
106
807
1.34
2.11
1.8
1.8
133.1
161.9
ug/g
0.60
83
613
70
500
1.42
2.06
1.3
1.3
—
—
—
0
0
44
286
1.55
2.05
1.5
1.5
301.3
264.0
ug/g
0.64
30
183
142
1132
1.28
2.04
1.2
1.2
16.4
14.3
u/ml
0.10
50
386
84
621
1.37
2.03
3.0
3.3
4.2
4.3
e9/l
0.02
55
422
12
50
2.41
2.02
1.4
1.9
73.5
71.6
%
0.15
12
45
108
831
1.32
2.02
3.5
3.9
0.1
0.1
%
0.10
49
264
56
385
1.47
2.01
4.2
3.6
4.0
3.9
mmol/l
0.36
51
354
87
648
1.36
2.01
2.0
1.8
1.8
2.9
ug/l
0.51
77
536
14
63
2.23
2.01
1.2
1.2
—
—
—
0
0
58
402
1.46
2.01
1.5
1.3
—
—
—
0
0
59
413
1.45
1.95
2.8
3.0
4.5
4.2
pmol/l
1.13
52
355
8
27
2.97
1.93
1.0
1.4
—
—
—
0
0
11
45
2.46
1.93
1.0
1.1
—
—
—
0
0
43
284
1.53
1.88
1.9
2.3
121.1
125.5
g/l
0.52
29
209
66
475
1.41
1.88
2.0
3.2
87.9
81.4
mg/l
0.06
52
382
100
770
1.32
1.87
3.5
3.9
0.4
0.5
%
0.04
38
219
43
286
1.52
1.83
2.5
2.5
14.7
15.5
%
0.55
23
133
23
130
1.78
1.82
1.1
1.1
—
—
—
0
0
19
101
1.89
1.81
3.6
3.3
—
—
—
0
0
20
110
1.83
1.73
1.1
1.0
—
—
—
0
0
46
315
1.48
1.72
5.2
5.9
11.1
11.2
mmol/l
0.08
46
276
46
315
1.48
1.72
5.2
5.9
103.8
105.2
mmol/l
1.31
46
276
261
2262
1.19
1.72
1.7
1.6
1.3
1.3
mmol/l
0.53
222
1839
65
476
1.38
1.70
2.0
3.2
31.7
91.3
mg/l
1.39
52
386
70
519
1.37
1.70
4.6
4.2
—
—
—
0
0
16
82
1.96
1.70
1.3
1.1
—
—
—
0
0
85
650
1.33
1.69
2.7
2.4
1.3
1.1
%
1.89
85
645
7
25
2.81
1.65
1.3
1.2
—
—
—
0
0
25
150
1.68
1.64
5.0
6.0
13.7
12.7
mg/l
0.61
19
140
87
672
1.31
1.63
2.8
2.5
—
—
—
0
0
36
238
1.53
1.61
1.1
1.3
—
—
—
0
0
62
456
1.38
1.60
3.0
2.9
1896.4
3579.6
u/ml
0.26
54
387
70
528
1.34
1.55
5.2
4.2
25.7
24.9
mmol/l
0.75
63
476
15
78
1.93
1.54
1.1
1.1
—
—
—
0
0
106
850
1.27
1.51
2.8
2.0
408.2
378.3
nmol/l
0.67
96
756
27
170
1.60
1.49
4.4
2.7
—
—
—
0
0
18
101
1.79
1.49
1.2
1.2
218.4
231.4
pmol/l
0.11
13
74
39
268
1.47
1.47
2.0
3.2
—
—
—
0
0
7
28
2.51
1.45
1.1
1.1
—
—
—
0
0
7
28
2.51
1.45
1.3
1.1
—
—
—
0
0
27
173
1.57
1.40
1.6
1.3
—
—
—
0
0
82
644
1.29
1.39
4.7
3.9
—
—
—
0
0
257
2267
1.16
1.38
1.3
1.3
—
—
—
0
0
6
23
2.62
1.37
1.3
1.5
—
—
—
0
0
17
98
1.74
1.31
1.5
1.5
—
—
—
0
0
6
24
2.51
1.30
1.8
1.1
—
—
—
0
0
14
76
1.85
1.30
1.2
1.2
—
—
—
0
0
8
34
2.36
1.29
1.3
2.8
—
—
—
0
0
296
2652
1.15
1.29
4.2
3.9
—
—
—
0
0
12
63
1.91
1.23
1.2
1.2
1.9
0.9
promille
—
7
46
30
204
1.48
1.23
1.6
1.3
—
—
—
0
0
29
196
1.49
1.22
1.4
1.3
704.6
530.5
mg/l
0.70
29
184
11
56
1.97
1.22
3.6
5.7
15.7
19.7
u/ml
—
5
14
11
56
1.97
1.22
4.8
3.4
—
—
—
0
0
16
93
1.73
1.21
1.4
1.4
—
—
—
0
0
34
238
1.44
1.21
1.1
1.3
56.8
60.0
mmol/l
0.21
28
190
10
50
2.01
1.16
4.8
3.4
—
—
—
0
0
10
50
2.01
1.16
1.2
1.1
—
—
—
0
0
8
39
2.06
1.15
1.3
1.1
—
—
—
0
0
37
266
1.40
1.15
1.6
1.6
—
—
—
0
0
18
111
1.63
1.12
1.2
1.1
173.3
303.8
u/ml
1.68
12
52
37
268
1.39
1.11
1.9
1.6
9026.9
18080.9
e6/l
1.70
24
191
28
193
1.46
1.09
2.9
3.4
58.5
61.2
%
0.55
28
193
5
21
2.39
1.09
1.2
1.7
—
—
—
0
0
5
21
2.39
1.09
1.4
1.6
—
—
—
0
0
35
253
1.39
1.07
1.2
1.3
—
—
—
0
0
56
438
1.29
1.03
2.2
2.0
—
—
—
0
0
14
83
1.69
1.01
1.6
1.9
4.4
5.1
mg/l
0.56
14
78
9
48
1.88
1.00
1.2
1.1
—
—
—
0
0
25
172
1.46
1.00
1.4
1.4
184.3
421.0
e6/l
0.64
19
142
25
172
1.46
1.00
1.3
1.3
145.7
35.7
e6/l
0.34
17
137
17
107
1.60
0.99
2.1
1.6
—
—
—
0
0
18
115
1.57
0.99
1.3
1.5
—
—
—
0
0
18
115
1.57
0.99
1.3
1.5
—
—
—
0
0
18
115
1.57
0.99
1.3
1.5
—
—
—
0
0
18
115
1.57
0.99
1.3
1.5
—
—
—
0
0
9
50
1.80
0.96
1.2
1.2
—
—
—
0
0
12
69
1.75
0.96
1.2
1.1
—
—
—
0
0
9
51
1.77
0.94
1.2
1.1
—
—
—
0
0
9
51
1.77
0.94
1.2
1.1
—
—
—
0
0
9
51
1.77
0.94
1.2
1.1
—
—
—
0
0
7
37
1.90
0.94
1.0
1.0
—
—
—
0
0
69
562
1.24
0.94
1.2
1.2
—
—
—
0
0
96
811
1.20
0.92
3.0
3.3
—
—
—
0
0
26
184
1.42
0.92
2.9
3.0
4.3
4.7
e9/l
0.73
26
184
46
359
1.29
0.89
2.0
3.3
—
—
—
0
0
20
135
1.49
0.89
1.5
1.3
—
—
—
0
0
8
42
1.91
0.88
1.3
1.4
—
—
—
0
0
21
144
1.46
0.87
1.3
1.2
—
—
—
0
0
6
31
1.94
0.84
1.7
1.4
—
—
—
0
0
6
31
1.94
0.84
1.0
1.4
—
—
—
0
0
8
45
1.78
0.84
1.9
3.0
2115.0
1836.9
ml
—
8
35
304
2809
1.10
0.81
1.8
1.8
431.3
8694135.3
pmol/l
1.06
247
2243
6
33
1.82
0.79
1.5
1.2
—
—
—
0
0
6
34
1.77
0.76
1.0
1.0
—
—
—
0
0
7
38
1.85
0.73
1.9
1.6
—
—
—
0
0
116
1019
1.15
0.73
4.9
3.6
1.2
1.2
mmol/l
0.02
100
880
52
425
1.23
0.72
3.1
3.2
0.8
0.9
nmol/l
1.43
40
326
5
25
2.00
0.72
1.2
1.2
—
—
—
0
0
10
60
1.67
0.72
1.9
1.3
31.3
23.6
iu/l
—
10
49
17
117
1.46
0.72
1.1
1.0
—
—
—
0
0
14
93
1.51
0.69
1.2
1.2
—
—
nmol/l
—
0
0
45
365
1.24
0.68
1.2
1.1
21.8
131.4
iu/ml
—
9
118
7
44
1.59
0.65
5.1
1.9
11.0
15.2
nmol/l
—
7
38
41
332
1.24
0.64
1.2
1.4
—
—
—
0
0
13
87
1.50
0.63
2.0
1.5
8.7
10.4
%
0.96
13
87
20
150
1.34
0.56
1.3
1.2
—
—
—
0
0
13
90
1.45
0.55
1.0
1.1
—
—
—
0
0
9
61
1.48
0.53
1.6
1.5
—
—
—
0
0
17
125
1.36
0.53
1.1
1.1
—
—
—
0
0
15
108
1.39
0.53
1.1
1.3
—
—
—
0
0
13
91
1.43
0.53
1.1
1.4
—
—
—
0
0
9
63
1.43
0.52
1.1
1.2
—
—
—
0
0
11
75
1.47
0.50
1.2
2.4
—
—
—
0
0
7
45
1.56
0.49
5.1
6.2
—
—
—
0
0
99
893
1.12
0.46
5.3
4.2
—
—
—
0
0
43
366
1.18
0.45
5.3
4.5
7.4
7.4
ph
1.11
35
301
32
266
1.21
0.43
2.7
2.3
—
—
—
0
0
81
726
1.12
0.43
1.5
1.6
—
—
—
0
0
11
78
1.41
0.43
4.5
14.6
—
—
—
0
0
5
31
1.61
0.43
1.8
1.1
52.2
65.3
%
—
5
23
27
221
1.23
0.42
2.7
1.2
35.5
43.8
u/l
0.25
22
191
13
96
1.36
0.41
1.0
1.2
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
249.2
—
0
9
0
15
0.00
0.41
0.0
1.7
—
—
—
0
0
26
213
1.22
0.41
2.8
2.4
—
—
—
0
0
0
17
0.00
0.40
0.0
1.2
—
—
—
0
0
0
17
0.00
0.40
0.0
1.2
—
—
—
0
0
0
17
0.00
0.40
0.0
1.2
—
—
—
0
0
0
18
0.00
0.40
0.0
1.6
—
—
—
0
0
0
18
0.00
0.40
0.0
1.6
—
—
—
0
0
5
35
1.43
0.39
1.0
1.1
—
—
—
0
0
221
2337
0.94
0.39
3.7
3.4
—
—
—
0
0
0
19
0.00
0.39
0.0
1.6
—
—
—
0
0
27
224
1.21
0.38
2.3
1.9
1.8
1.7
mmol/l
0.20
27
215
9
66
1.37
0.38
1.4
2.6
—
—
—
0
0
12
89
1.35
0.38
1.2
1.2
1.8
6.7
u/ml
—
5
41
20
161
1.25
0.37
2.1
1.4
3.1
4.3
iu/l
—
8
42
36
309
1.17
0.36
5.2
4.8
2.5
2.7
mmol/l
0.16
26
207
6
44
1.37
0.34
1.0
1.0
—
—
—
0
0
6
44
1.37
0.34
1.2
1.3
—
—
—
0
0
10
133
0.75
0.33
1.2
1.7
—
—
—
0
0
12
92
1.31
0.32
1.3
1.2
—
—
—
0
0
13
101
1.29
0.31
1.3
1.6
0.7
1.0
g/l
—
8
79
17
138
1.23
0.30
1.5
1.4
—
—
—
0
0
7
54
1.30
0.30
1.0
1.1
—
—
—
0
0
7
55
1.27
0.30
2.0
2.2
—
—
—
0
0
36
316
1.14
0.29
14.8
13.4
—
—
—
0
0
8
62
1.29
0.28
2.3
2.1
—
—
—
0
0
21
177
1.19
0.27
1.1
1.1
—
—
—
0
0
9
116
0.77
0.27
2.2
1.9
164.2
210.7
pmol/l
—
9
107
29
327
0.88
0.23
1.0
1.2
—
—
—
0
0
19
221
0.86
0.22
1.4
1.3
—
—
—
0
0
17
144
1.18
0.22
1.1
1.1
—
—
—
0
0
5
42
1.19
0.21
1.4
1.7
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
2.0
—
15.0
—
0
10
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
8
105
0.76
0.21
1.6
1.8
—
—
—
0
0
0
13
0.00
0.21
0.0
7.1
—
—
—
0
0
6
49
1.23
0.20
1.0
1.2
196.7
133.1
nmol/l
—
6
49
6
50
1.20
0.19
1.2
1.0
—
—
—
0
0
15
127
1.18
0.19
2.3
2.0
—
—
—
0
0
47
436
1.08
0.17
2.8
2.6
0.3
0.3
g/l
0.25
20
164
16
139
1.15
0.16
3.0
2.7
—
—
—
0
0
29
265
1.10
0.14
1.8
2.3
—
—
—
0
0
15
171
0.88
0.14
1.5
1.4
—
—
—
0
0
9
83
1.08
0.14
1.3
1.1
—
232.1
—
0
18
25
233
1.07
0.09
1.4
1.4
1196.8
1571.5
e6/l
0.37
18
169
5
63
0.79
0.08
2.2
3.3
68.6
111.3
nmol/l
—
5
63
67
693
0.97
0.08
2.0
2.2
11.5
11.3
nmol/l
0.07
56
580
15
164
0.91
0.08
1.2
1.3
—
—
—
0
0
73
709
1.03
0.07
4.1
3.9
—
—
—
0
0
44
424
1.04
0.06
4.5
4.5
—
—
—
0
0
14
129
1.09
0.05
2.4
1.2
—
—
—
0
0
21
199
1.06
0.04
1.9
2.1
56.4
59.5
%
0.24
21
199
20
210
0.95
0.03
1.5
1.5
—
—
—
0
0
20
210
0.95
0.03
1.1
1.1
—
—
—
0
0
19
181
1.05
0.03
1.5
1.5
—
—
—
0
0
12
112
1.07
0.03
2.6
1.7
206.1
294.7
mu/l
1.91
12
100
28
288
0.97
0.02
4.1
3.8
25.2
31.2
mg/l
0.36
21
198
22
214
1.03
0.00
1.3
1.4
32468.9
66826.7
e6/l
0.65
12
130
22
214
1.03
0.00
1.6
1.6
—
—
—
0
0
13
126
1.03
0.00
1.0
1.2
—
—
—
0
0
16
158
1.01
0.00
1.4
1.4
—
—
—
0
0
17
167
1.02
0.00
1.4
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
3.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
8
80
1.00
0.00
1.4
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
6
61
0.98
0.00
1.3
1.2
—
—
—
0
0
7
75
0.93
0.00
2.9
2.2
—
—
—
0
0
7
76
0.92
0.00
1.7
1.4
—
—
—
0
0
5
56
0.89
0.00
1.0
1.0
283.4
294.5
mg/l
—
5
47
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint H7_ECTROPION and mortality.

Females

Parameter HR [95% CI] p-value
H7_ECTROPION 1.089 [0.97, 1.22] 0.15
Birth year 0.994 [0.99, 1.0] 0.15

During the follow-up period (1.1.1998 — 31.12.2019), 2074 out of 4377 females with H7_ECTROPION died.

Males

Parameter HR [95% CI] p-value
H7_ECTROPION 1.213 [1.06, 1.38] 0.004
Birth year 0.986 [0.98, 1.0] 0.003

During the follow-up period (1.1.1998 — 31.12.2019), 2725 out of 5467 males with H7_ECTROPION died.

Mortality risk

Mortality risk for people of age

years, who have H7_ECTROPION.

N-year risk Females Males
1 0.076% 0.239%
5 0.598% 1.342%
10 1.433% 3.469%
15 2.943% 6.614%
20 5.09% 11.054%

Relationships between endpoints

Index endpoint: H7_ECTROPION – Ectropion of eyelid

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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