Other complications of labour and delivery, not elsewhere classified

O15_LABOUR_OTHER

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

only females

293373

2. Check conditions

None

293373

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 O75
  • Hospital discharge: ICD-9 669
  • Cause of death: ICD-10 O75
  • Cause of death: ICD-9 669

2 out of 7 registries used, show all original rules.

5266

4. Check minimum number of events

None

5266

5. Include endpoints

None

5266

6. Filter based on genotype QC (FinnGen only)

5266

Control definitions (FinnGen only)

Control exclude
O15_COMPLIC_LAB_DELIV

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF3
Parent code in ICD-10
O60-O75
Name in latin
Aliae complicationes laborum et partus non alibi classificatae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 36529 36529 -
Only index persons 36229 36229 -
Unadjusted period prevalence (%)
Whole population 1.05 1.05 -
Only index persons 1.33 1.33 -
Median age at first event (years)
Whole population - 30.57 -
Only index persons - 30.55 -

-FinnGen-

Key figures

All Female Male
Number of individuals 5266 5266 -
Unadjusted period prevalence (%) 1.79 1.79 -
Median age at first event (years) 31.14 31.14 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
4557
Matched controls
45029
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
6.1
323.0
3431
15056
SPAT1380
SPAT
Postpartum check-up
4.4
323.0
2040
6993
O82.10
ICD-10 Finland
Delivery by emergency caesarean section
12.8
323.0
809
748
SPAT1197
SPAT
Extensive health check-up of expecting family
5.4
323.0
2720
9661
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
4.3
323.0
2474
9751
O72.1
ICD-10 Finland
Other immediate postpartum haemorrhage
564.2
323.0
320
6
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
3.6
323.0
2284
9908
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
7.0
323.0
1342
2548
WX307
NOMESCO Finland
Obstetric epidural analgesia
4.8
323.0
1796
5358
O75.7
ICD-10 Finland
Vaginal delivery following previous caesarean section
+∞
323.0
328
*
O68.0
ICD-10 Finland
Labour and delivery complicated by fetal heart rate anomaly
8076.4
323.0
705
*
W78
ICPC
Pregnancy
5.4
323.0
2994
11717
O75.0
ICD-10 Finland
Maternal distress during labour and delivery
+∞
323.0
1450
*
Z39.2
ICD-10 Finland
Routine postpartum follow-up
5.0
323.0
2488
8745
MAE00
NOMESCO Finland
Outlet vacuum delivery
81.8
323.0
1339
228
O34.2
ICD-10 Finland
Maternal care due to uterine scar from previous surgery
9.8
323.0
820
986
SPAT1379
SPAT
Health check-up of pregnant person
4.0
323.0
2208
8506
O63.1
ICD-10 Finland
Prolonged second stage (of labour)
+∞
323.0
623
*
O75.6
ICD-10 Finland
Delayed delivery after spontaneous or unspecified rupture of membranes
+∞
323.0
2169
*
O81.4
ICD-10 Finland
Vacuum extractor delivery
103.8
323.0
1667
249
O64.0
ICD-10 Finland
Obstructed labour due to incomplete rotation of fetal head
+∞
323.0
372
*
O70.1
ICD-10 Finland
Second degree perineal laceration during delivery
749.6
323.0
415
6
O63.0
ICD-10 Finland
Prolonged first stage (of labour)
+∞
323.0
351
*
MA5AE
NOMESCO Finland
Morphology ultrasound screening, weeks 18+0 to 21+6 of gestation
5.1
314.5
1142
2754
Z34.0
ICD-10 Finland
Supervision of normal first pregnancy
3.5
303.3
2014
8377
Z37.0
ICD-10 Finland
Single live birth
3.9
303.1
1615
5618
MA3AE
NOMESCO Finland
Combined first trimester screening
5.0
297.1
1106
2721
MA2JE
NOMESCO Finland
Ultrasound screening of fetal nuchal translucency
3.8
292.7
1564
5423
O72.0
ICD-10 Finland
Third-stage haemorrhage
+∞
264.0
252
*
O75.2
ICD-10 Finland
Pyrexia during labour, not elsewhere classified
+∞
261.9
250
*
WX306
NOMESCO Finland
Lumbar epidural anesthesy
4.8
255.8
983
2459
MAC40
NOMESCO Finland
Pharmacological induction or advancement of labor
9.8
249.4
533
599
Z34.9
ICD-10 Finland
Supervision of normal pregnancy, unspecified
3.3
246.3
1662
6735
ZXD05
NOMESCO Finland
Urgent procedure
3.1
245.1
1913
8584
Z34.8
ICD-10 Finland
Supervision of other normal pregnancy
3.0
237.8
1946
8962
O99.80
ICD-10 Finland
The fear of childbirth
4.8
232.0
882
2162
O60
ICD-10 Finland
Preterm labour and delivery
593.4
231.8
229
*
Z3232
NOMESCO Finland
Midwife
3.2
213.3
1420
5582
SPAT1317
SPAT
Planned health check-up monitoring, health check-up performed based on individual need
3.1
208.5
1447
5837
Z32.1
ICD-10 Finland
Pregnancy confirmed
3.0
198.7
1517
6488
O24.4
ICD-10 Finland
Diabetes mellitus arising in pregnancy
3.3
194.9
1167
4197
O75.3
ICD-10 Finland
Other infection during labour
+∞
193.3
185
*
SPAT1399
SPAT
Acceptance of acknowledgement of paternity of child born outside of marriage before the birth of the child at the maternity clinic. Paternity Act, Section 16.
4.1
192.5
855
2400
6690A
ICD-9 Finland
Other complications of labour and delivery, not elsewhere classified, Maternal distress
+∞
187.0
179
*
O42.9
ICD-10 Finland
Premature rupture of membranes, unspecified
5.0
178.4
627
1386
TMA00
NOMESCO Finland
Episiotomy
5.0
175.8
623
1388
SPAT1195
SPAT
Antenatal classes
4.6
170.8
657
1592
Z34
ICD-10 Finland
Supervision of normal pregnancy
3.7
170.6
872
2738
MAC10
NOMESCO Finland
Antepartum dilatation of cervical canal
5.9
163.3
493
908
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
3.2
162.9
1020
3727
MAC01
NOMESCO Finland
Rupture of aminiotic membrane for induction of labor
6.8
162.1
436
690
WX322
NOMESCO Finland
Combined spinal-epidural analgesia in obstetrics
6.3
159.6
454
774
MA1AE
NOMESCO Finland
Ultrasound examination of early pregnancy (before 12. postmenstrual week)
2.6
151.9
1452
6889
W92
ICPC
Compl labour/ delivery livebirth
7.4
149.2
378
547
W85
ICPC
Gestational diabetes
3.8
147.4
711
2106
O61.0
ICD-10 Finland
Failed medical induction of labour
+∞
138.6
133
*
MBC30
NOMESCO Finland
Repair of partial rupture of perineum
10.8
136.3
272
262
O64.1
ICD-10 Finland
Obstructed labour due to breech presentation
1289.6
130.3
127
*
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
2.7
129.7
1052
4470
MAX99
NOMESCO Finland
Assistance to normal delivery
2.4
128.7
1430
7223
O72.2
ICD-10 Finland
Delayed and secondary postpartum haemorrhage
68.6
127.9
148
22
WX600
NOMESCO Finland
Single shot through catheter
9.5
123.4
264
289
O62.1
ICD-10 Finland
Secondary uterine inertia
+∞
121.9
117
*
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
2.6
119.9
1065
4741
MBA30
NOMESCO Finland
Manual removal of placenta from delivered uterus
33.3
113.1
150
46
O70.0
ICD-10 Finland
First degree perineal laceration during delivery
560.1
111.9
111
*
W84
ICPC
Pregnancy high risk
3.3
99.1
563
1858
OAA11
SPAT
NA
3.4
98.3
522
1639
OAA12
SPAT
NA
5.1
97.4
329
680
O80.8
ICD-10 Finland
Other single spontaneous delivery
3.0
96.4
636
2330
ZXE00
NOMESCO Finland
One hour or less
1.9
91.1
1888
12040
O68.1
ICD-10 Finland
Labour and delivery complicated by meconium in amniotic fluid
+∞
90.5
87
*
O68.8
ICD-10 Finland
Labour and delivery complicated by other evidence of fetal stress
+∞
87.4
84
*
WX321
NOMESCO Finland
Acute spinal anesthesia for delivery
2.8
87.2
632
2448
O71.4
ICD-10 Finland
Obstetric high vaginal laceration
+∞
81.1
78
*
O62.0
ICD-10 Finland
Primary inadequate contractions
+∞
79.0
76
*
O41.1
ICD-10 Finland
Infection of amniotic sac and membranes
14.0
78.9
138
100
MA2DE
NOMESCO Finland
Detailed ultrasound examination of fetus including color doppler method
2.2
78.4
969
4951
R3110
NOMESCO Finland
Psychosocial training
5.1
76.5
255
517
O64.8
ICD-10 Finland
Obstructed labour due to other malposition and malpresentation
690.6
69.9
69
*
O75.5
ICD-10 Finland
Delayed delivery after artificial rupture of membranes
+∞
69.6
67
*
W90
ICPC
Uncompl labour/delivery livebirth
2.3
67.7
703
3284
MBA04
NOMESCO Finland
Curettage of uterus after delivery
41.2
65.2
82
20
MBC33
NOMESCO Finland
Repair of complete rupture of perineum
100.4
63.7
70
7
O69.1
ICD-10 Finland
Labour and delivery complicated by cord around neck, with compression
+∞
63.4
61
*
SPAT1200
SPAT
Guidance for breast-feeding and breast care
3.0
63.3
397
1387
WX320
NOMESCO Finland
Spinalanesthesy
2.2
63.1
720
3507
Z39.1
ICD-10 Finland
Care and examination of lactating mother
3.9
63.0
280
752
O36.6
ICD-10 Finland
Maternal care for excessive fetal growth
3.0
62.4
384
1324
O73.0
ICD-10 Finland
Retained placenta without haemorrhage
+∞
62.4
60
*
O68.2
ICD-10 Finland
Labour and delivery complicated by fetal heart rate anomaly with meconium in amniotic fluid
+∞
61.3
59
*
MAC96
NOMESCO Finland
Other induction or advancement of labour
3.4
59.4
313
965
MAW96
NOMESCO Finland
Other operation in pregnancy or at delivery
11.0
59.4
116
107
O68.3
ICD-10 Finland
Labour and delivery complicated by biochemical evidence of fetal stress
+∞
58.2
56
*
WX230
NOMESCO Finland
Plexus blockade of nervus pudendus
4.4
57.2
218
508
8811
FHL
Cesarean section
6.7
55.6
147
224
O42.1
ICD-10 Finland
Premature rupture of membranes, onset of labour after 24 hours
5.5
55.3
171
318
Z36.0
ICD-10 Finland
Antenatal screening for chromosomal anomalies
2.3
54.4
588
2780
W29
ICPC
Pregnancy symptom/complaint other
2.8
54.1
379
1417
SPAT1373
SPAT
Combined screening in early pregnancy
3.5
54.0
272
809
Z35.0
ICD-10 Finland
Supervision of pregnancy with history of infertility
3.1
54.0
326
1108
Z32.0
ICD-10 Finland
Pregnancy, not (yet) confirmed
2.9
53.0
357
1301
O70.2
ICD-10 Finland
Third degree perineal laceration during delivery
+∞
53.0
51
*
SPAT1246
SPAT
Screening of depression or other psychiatric problem
2.4
51.6
502
2252
Z35.2
ICD-10 Finland
Supervision of pregnancy with other poor reproductive or obstetric history
4.2
51.4
207
508
O99.89
ICD-10 Finland
Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
3.4
50.9
266
814
O26.82
ICD-10 Finland
Exhaustion and fatigue pregnancy-related
3.3
49.4
270
854
O80.0
ICD-10 Finland
Spontaneous vertex delivery
1.6
49.0
2396
18514
MAE03
NOMESCO Finland
Mid-cavity or high vacuum delivery
69.9
48.9
56
8
SPAT1196
SPAT
Monitoring of normal pregnancy
1.9
48.6
838
4777
O73.1
ICD-10 Finland
Retained portions of placenta and membranes, without haemorrhage
+∞
47.8
46
*
O82.11
ICD-10 Finland
Childbirth with an emergency caesarean section in an emergency
17.3
47.7
76
44
O62.2
ICD-10 Finland
Other uterine inertia
127.4
47.6
51
*
MAA40
NOMESCO Finland
Puncture of fetus
8.8
47.0
103
118
O66.5
ICD-10 Finland
Failed application of vacuum extractor and forceps, unspecified
+∞
46.7
45
*
O61.1
ICD-10 Finland
Failed instrumental induction of labour
+∞
45.7
44
*
O66.0
ICD-10 Finland
Obstructed labour due to shoulder dystocia
+∞
45.7
44
*
O48
ICD-10 Finland
Prolonged pregnancy
2.6
44.8
343
1350
MBC10
NOMESCO Finland
Repair of obstetric laceration of vagina
3.6
44.3
210
595
8801
FHL
Suction cup delivery
10.2
43.6
88
87
O86.0
ICD-10 Finland
Infection of obstetric surgical wound
6.5
43.2
116
181
O32.1
ICD-10 Finland
Maternal care for breech presentation
2.4
42.6
381
1632
Z35.9
ICD-10 Finland
Supervision of high-risk pregnancy, unspecified
2.6
41.1
331
1339
O70.21
ICD-10 Finland
III degree perineal tear involving less than one half of external anal sphincter thickness torn during childbirth
+∞
40.5
39
*
Z36.8
ICD-10 Finland
Other antenatal screening
3.1
40.1
234
772
MA2XE
NOMESCO Finland
Other obstetric ultrasound examination
1.9
39.4
631
3478
OAA10
SPAT
NA
2.9
38.7
250
886
O61.8
ICD-10 Finland
Other failed induction of labour
+∞
38.4
37
*
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
3.2
37.7
208
662
O65.4
ICD-10 Finland
Obstructed labour due to fetopelvic disproportion, unspecified
132.9
37.6
40
*
WW500
NOMESCO Finland
Blood transfusion
4.5
36.2
131
291
SPAT1189
SPAT
Other ultrasound examination during pregnancy
2.2
36.1
406
1938
B01AB05
ATC
enoxaparin; parenteral
1.8
35.6
771
4689
O23.5
ICD-10 Finland
Infections of the genital tract in pregnancy
3.9
34.8
149
388
MAE20
NOMESCO Finland
Failed vacuum delivery
122.8
34.5
37
*
OAB30
SPAT
NA
5.4
34.5
107
201
WYA40
NOMESCO Finland
Assessment of oral health and treatment needs for family expecting first child
2.8
34.5
239
886
O36.9
ICD-10 Finland
Maternal care for fetal problem, unspecified
4.0
34.4
141
353
O42.0
ICD-10 Finland
Premature rupture of membranes, onset of labour within 24 hours
3.4
34.4
177
536
SPAT1315
SPAT
Periodic health check-up of children and adolescents
2.1
34.2
401
1947
O21.9
ICD-10 Finland
Vomiting of pregnancy, unspecified
3.1
33.4
193
636
O80.9
ICD-10 Finland
Single spontaneous delivery, unspecified
4.0
33.3
136
340
O99.3
ICD-10 Finland
Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
2.8
33.2
221
798
SPAT1357
SPAT
Monitoring of problem during pregnancy
2.3
32.3
317
1417
ZXD00
NOMESCO Finland
Emergency procedure
3.6
31.9
149
418
O02.1
ICD-10 Finland
Missed abortion
1.9
31.8
480
2578
O20.9
ICD-10 Finland
Haemorrhage in early pregnancy, unspecified
2.4
30.8
288
1256
6611B
ICD-9 Finland
Abnormality of forces of labour, Secondary uterine inertia
+∞
30.1
29
*
A02BC01
ATC
omeprazole; systemic
1.6
29.7
876
5789
6500B
ICD-9 Finland
Delivery in a completely normal case[PARTUS SINE COMPLICATIONE]
0.4
29.1
135
3125
Z35
ICD-10 Finland
Supervision of high-risk pregnancy
3.5
28.8
138
396
O13
ICD-10 Finland
Gestational [pregnancy-induced] hypertension
2.0
28.6
374
1898
6698X
ICD-9 Finland
Other complications of labour and delivery, not elsewhere classified, Other complications of labour and delivery
+∞
28.0
27
*
TQW30
NOMESCO Finland
Acupuncture
4.9
28.0
93
190
Z39
ICD-10 Finland
Postpartum care and examination
3.2
28.0
151
475
O35.1
ICD-10 Finland
Maternal care for (suspected) chromosomal abnormality in fetus
3.0
27.6
167
569
W19
ICPC
Lactation symptom/complaint
4.9
26.9
90
185
SPAT1249
SPAT
Treatment-related counselling outside office
1.4
26.5
1907
15194
O82.0
ICD-10 Finland
Delivery by elective caesarean section
2.1
26.3
314
1533
O47.9
ICD-10 Finland
False labour, unspecified
2.8
26.3
178
651
OAA41
SPAT
NA
3.5
25.9
126
367
OAA70
SPAT
NA
3.8
25.8
111
292
N97.9
ICD-10 Finland
Female infertility, unspecified
1.7
25.8
551
3315
Z32
ICD-10 Finland
Pregnancy examination and test
3.4
25.0
127
382
O35.8
ICD-10 Finland
Maternal care for other (suspected) fetal abnormality and damage
2.6
25.0
195
775
6622B
ICD-9 Finland
Long labour, Prolonged second stage
+∞
24.9
24
*
MBA40
NOMESCO Finland
Pharmacological evacuation of uterus after abortion
2.5
24.8
194
772
Z87.5
ICD-10 Finland
Personal history of complications of pregnancy, childbirth and the puerperium
4.1
24.7
99
245
G03GA05
ATC
follitropin alfa; parenteral
2.1
24.1
299
1483
MBC20
NOMESCO Finland
Repair of obstetric laceration of vulva
7.5
24.0
57
76
N61
ICD-10 Finland
Inflammatory disorders of breast
2.2
23.5
244
1119
WX234
NOMESCO Finland
Paracervical blockade
2.0
23.4
297
1488
O70.22
ICD-10 Finland
III degree perineal tear involving one half or more of external anal sphincter thickness torn during childbirth
+∞
22.8
22
*
Z2221
NOMESCO Finland
Medical doctor
1.4
22.8
1257
9465
O67.9
ICD-10 Finland
Intrapartum haemorrhage, unspecified
+∞
21.8
21
*
O75.8
ICD-10 Finland
Other specified complications of labour and delivery
+∞
21.8
21
*
O86.1
ICD-10 Finland
Other infection of genital tract following delivery
4.0
21.2
85
211
O41.8
ICD-10 Finland
Other specified disorders of amniotic fluid and membranes
7.7
20.8
48
62
O26.88
ICD-10 Finland
Other specified pregnancy-related conditions
2.7
20.7
148
562
O46.9
ICD-10 Finland
Antepartum haemorrhage, unspecified
2.6
20.3
152
590
LA2AE
NOMESCO Finland
Ultrasound examination of ovarian cyst
2.1
20.2
238
1155
P01AB01
ATC
metronidazole; oral, rectal
1.4
19.6
1629
13092
O61.9
ICD-10 Finland
Failed induction of labour, unspecified
198.4
19.5
20
*
G03GA01
ATC
chorionic gonadotrophin; parenteral
1.9
19.4
319
1760
SPAT1381
SPAT
Extensive health check-up at 4 months of age
3.7
19.0
84
228
O99.0
ICD-10 Finland
Anaemia complicating pregnancy, childbirth and the puerperium
3.1
18.9
103
329
O03.9
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, without complication
1.8
18.7
366
2136
O75.4
ICD-10 Finland
Other complications of obstetric surgery and procedures
+∞
18.7
18
*
WZB00
SPAT
NA
0.5
18.3
116
2408
O65.5
ICD-10 Finland
Obstructed labour due to abnormality of maternal pelvic organs
+∞
17.6
17
*
MBA05
NOMESCO Finland
Curettage of uterus after abortion
2.8
17.6
116
419
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
0.5
17.4
105
2216
W05
ICPC
Pregnancy vomiting/nausea
2.8
17.2
112
403
OAA48
SPAT
NA
3.3
17.2
86
259
TLW00
NOMESCO Finland
Insemination
2.1
17.2
204
995
O40
ICD-10 Finland
Polyhydramnios
3.1
17.1
95
309
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.4
16.9
1167
9050
O21
ICD-10 Finland
Excessive vomiting in pregnancy
2.9
16.8
100
340
O91.2
ICD-10 Finland
Nonpurulent mastitis associated with childbirth
2.5
16.8
130
515
6699X
ICD-9 Finland
Other complications of labour and delivery, not elsewhere classified, Unspecified complication of labour and delivery
+∞
16.6
16
*
6441A
ICD-9 Finland
Early or threatened labour, Other threatened labour
+∞
16.6
16
*
O64.3
ICD-10 Finland
Obstructed labour due to brow presentation
168.6
16.4
17
*
O71.3
ICD-10 Finland
Obstetric laceration of cervix
168.6
16.4
17
*
O47
ICD-10 Finland
False labour
2.8
15.9
102
362
SPAT1375
SPAT
Structural ultrasound screening, weeks 18+0-21+6
2.6
15.9
121
476
N02BE01
ATC
paracetamol; systemic, rectal
1.3
15.9
3410
31065
6660A
ICD-9 Finland
Postpartum haemorrhage, Third-stage haemorrhage[HAEMORRHAGIA POST PARTUM STADII III]
+∞
15.6
15
*
N05AX12
ATC
aripiprazole; systemic
0.4
15.5
75
1712
O99.1
ICD-10 Finland
Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
3.2
15.4
82
259
F29
ICD-10 Finland
Unspecified nonorganic psychosis
0.4
15.2
53
1372
MWA00
NOMESCO Finland
Repair of wound dehiscence in obstetric surgery
10.3
15.0
29
28
L02BG04
ATC
letrozole; oral
1.8
14.9
267
1514
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
2.1
14.8
166
790
6522B
ICD-9 Finland
Malposition and malpresentation of foetus, Breech presentation without mention of version[PRAESENTATIO CLUNIUM,SYNNYTYKSEN AIKANA]
+∞
14.5
14
*
W18
ICPC
Post-partum symptom/complaint other
3.5
14.5
68
196
LAA10
NOMESCO Finland
Percutaneous or transvaginal puncture and recovery of oocyte
1.8
14.4
230
1259
O85
ICD-10 Finland
Puerperal sepsis
3.0
14.3
82
271
SPAT1389
SPAT
Visit based on need for special support
1.9
14.3
209
1106
MAA00
NOMESCO Finland
Amniocentesis
2.2
14.1
145
667
J01DB01
ATC
cefalexin; oral
1.3
14.1
3509
32272
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.5
14.1
483
3267
N05AH03
ATC
olanzapine; systemic
0.5
13.9
94
1908
N05AH04
ATC
quetiapine; oral
0.7
13.4
473
6449
MBC00
NOMESCO Finland
Repair of obstetric laceration of cervix uteri
33.7
13.4
17
5
O16
ICD-10 Finland
Unspecified maternal hypertension
4.4
13.3
47
106
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
1.6
13.1
337
2126
O26.7
ICD-10 Finland
Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium
2.5
13.1
101
403
SPAT1312
SPAT
General health counselling
1.3
13.1
1456
12023
NE1AG
NOMESCO Finland
MRI pelvimetry with high intensity magnet
3.1
13.0
69
219
N05AH02
ATC
clozapine; systemic
0.2
13.0
9
551
TLW10
NOMESCO Finland
Transfer of fresh embryo
2.0
12.9
161
802
H01CC01
ATC
ganirelix; parenteral
1.8
12.8
218
1221
Z30.1
ICD-10 Finland
Insertion of (intrauterine) contraceptive device
1.3
12.7
1129
9031
6620B
ICD-9 Finland
Long labour, Prolonged first stage
+∞
12.4
12
*
6631A
ICD-9 Finland
Umbilical cord complications, Cord around neck, with compression
+∞
12.4
12
*
6694X
ICD-9 Finland
Other complications of labour and delivery, not elsewhere classified, Other complications of obstetrical surgery and procedures
+∞
12.4
12
*
O64.9
ICD-10 Finland
Obstructed labour due to malposition and malpresentation, unspecified
+∞
12.4
12
*
O47.1
ICD-10 Finland
False labour at or after 37 completed weeks of gestation
1.6
12.4
295
1820
O41.0
ICD-10 Finland
Oligohydramnios
2.1
12.4
144
697
Z39.0
ICD-10 Finland
Care and examination immediately after delivery
2.4
12.3
102
424
H01CA02
ATC
nafarelin; nasal
1.9
12.2
191
1039
O14.9
ICD-10 Finland
Pre-eclampsia, unspecified
2.3
12.2
110
477
TLW12
NOMESCO Finland
Insertion of frozen embryo
2.0
12.1
153
766
E66.01
ICD-10 Finland
Obesity due to excess calories
1.5
11.9
387
2584
ZXE10
NOMESCO Finland
More than one and less than three hours
1.3
11.9
1004
7962
O24
ICD-10 Finland
Diabetes mellitus in pregnancy
4.0
11.9
46
114
TMW99
NOMESCO Finland
Other minor surgical procedure in obstetrics
2.9
11.8
71
246
O20.0
ICD-10 Finland
Threatened abortion
1.9
11.7
167
881
A98
ICPC
Health maint/preventive medicine
2.2
11.6
4489
43578
MBA03
NOMESCO Finland
Curettage of uterus after delivery or abortion
2.1
11.6
134
652
SPAT1382
SPAT
Extensive health check-up at 18 months of age
2.9
11.5
67
227
O69.0
ICD-10 Finland
Labour and delivery complicated by prolapse of cord
+∞
11.4
11
*
O68.9
ICD-10 Finland
Labour and delivery complicated by fetal stress, unspecified
+∞
11.4
11
*
6528B
ICD-9 Finland
Malposition and malpresentation of foetus, Other specified malposition or malpresentation[MUUT VIRHEASENNOT JA -TARJONNAT, SYNNYTYKSEN AIKANA]
+∞
11.4
11
*
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.3
11.3
1310
10829
R52.0
ICD-10 Finland
Acute pain
2.0
11.2
146
745
SPAT1391
SPAT
Counselling and guidance related to family situation
2.1
10.9
117
551
N06AX12
ATC
bupropion; oral
0.6
10.8
178
2827
O90.8
ICD-10 Finland
Other complications of the puerperium, not elsewhere classified
6.8
10.7
26
38
W78
ICD-10 Finland
Inhalation of gastric contents
5.0
10.6
33
66
O20.8
ICD-10 Finland
Other haemorrhage in early pregnancy
3.2
10.6
53
163
O10.0
ICD-10 Finland
Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium
2.3
10.5
96
419
O75.9
ICD-10 Finland
Complication of labour and delivery, unspecified
+∞
10.4
10
*
O69.2
ICD-10 Finland
Labour and delivery complicated by other cord entanglement, with compression
+∞
10.4
10
*
O67.8
ICD-10 Finland
Other intrapartum haemorrhage
+∞
10.4
10
*
6440B
ICD-9 Finland
Early or threatened labour, Threatened premature labour[PARTUS PRAEMATURUS]
+∞
10.4
10
*
O03.4
ICD-10 Finland
Spontaneous abortion, Incomplete, without complication
1.8
10.3
168
928
W27
ICPC
Fear of complications of pregnancy
2.2
10.2
102
466
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
0.2
10.2
7
432
MBA96
NOMESCO Finland
Other removal of retained products of conception after delivery or abortion
2.0
10.0
124
621
LA2HE
NOMESCO Finland
Repeated measurement of ovarian cyst
2.5
10.0
78
316
N05AX08
ATC
risperidone; systemic
0.5
9.9
92
1698
N96
ICD-10 Finland
Habitual aborter
2.6
9.9
71
275
O32.2
ICD-10 Finland
Maternal care for transverse and oblique lie
3.1
9.7
51
163
N03AX09
ATC
lamotrigine; oral
0.6
9.7
124
2096
O86.8
ICD-10 Finland
Other specified puerperal infections
4.1
9.7
36
87
O36.8
ICD-10 Finland
Maternal care for other specified fetal problems
2.0
9.6
124
632
F20.9
ICD-10 Finland
Schizophrenia, unspecified
0.2
9.6
9
453
SPAT1273
SPAT
Structured assessment of psychoactive substance / tobacco use
1.6
9.5
232
1445
MAC02
NOMESCO Finland
Rupture of aminiotic membrane for advancement of labor
3.0
9.5
53
177
LGA10
NOMESCO Finland
Sterilisation by destruction or division of Fallopian tubes
3.9
9.4
37
94
H3603, E103
ICD-10 Finland
NA
0.0
9.4
*
267
Z35.5
ICD-10 Finland
Supervision of elderly primigravida
3.6
9.4
40
109
O70.3
ICD-10 Finland
Fourth degree perineal laceration during delivery
99.0
9.4
10
*
O02.0
ICD-10 Finland
Blighted ovum and nonhydatidiform mole
1.7
9.3
197
1179
A10AE04
ATC
insulin glargine; parenteral
0.5
9.3
57
1196
O66.4
ICD-10 Finland
Failed trial of labour, unspecified
+∞
9.3
9
*
O66.2
ICD-10 Finland
Obstructed labour due to unusually large fetus
+∞
9.3
9
*
6542B
ICD-9 Finland
Abnormality of organs and soft tissues of pelvis, Previous Caesarean delivery[CICATRIX UTERI POSTOPERATIVA, SYNNYTYKSEN AIKANA]
8.6
9.2
19
22
P72
ICPC
Schizophrenia
0.2
9.1
6
380
Z76.0
ICD-10 Finland
Issue of repeat prescription
0.7
8.8
357
4775
XMA22
NOMESCO Finland
General examination of pregnant woman
1.4
8.7
399
2855
N81.6
ICD-10 Finland
Rectocele
2.0
8.7
112
572
N97.0
ICD-10 Finland
Female infertility associated with anovulation
1.7
8.6
180
1077
O99.4
ICD-10 Finland
Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
2.8
8.6
52
184
O99.5
ICD-10 Finland
Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium
2.6
8.6
60
232
N06AX16
ATC
venlafaxine; oral
0.7
8.5
399
5222
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.2
8.5
1737
15174
65000
ICD-8 Finland
Delivery without mention of complication, Occipital presentation
0.4
8.5
46
1006
Z36.4
ICD-10 Finland
Antenatal screening for fetal growth retardation using ultrasound and other physical methods
2.1
8.4
92
439
SPAT1192
SPAT
Gynaecological examination
1.3
8.4
937
7661
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
0.2
8.4
8
398
Z71.8
ICD-10 Finland
Other specified counselling
1.2
8.4
1107
9236
MAB20
NOMESCO Finland
Failed external version
2.1
8.3
87
409
LC2HE
NOMESCO Finland
Hystero-salpingography with ultrasound
1.5
8.3
311
2141
Z20.2
ICD-10 Finland
Contact with and exposure to infections with a predominantly sexual mode of transmission
0.5
8.3
72
1351
6610B
ICD-9 Finland
Abnormality of forces of labour, Primary uterine inertia
+∞
8.3
8
*
6534B
ICD-9 Finland
Disproportion, Foetopelvic disproportion[DISPROPORTIO FOETOPELVICA,SYNNYTYKSEN AIKANA]
+∞
8.3
8
*
MA4AT
NOMESCO Finland
Chorion biopsy with ultrasound guidance
2.9
8.3
48
165
D25.9
ICD-10 Finland
Leiomyoma of uterus, unspecified
0.6
8.2
114
1884
XCK10
NOMESCO Finland
Photography of fundus of eye
0.5
8.2
58
1156
F20.30
ICD-10 Finland
Undifferentiated schizophrenia continuous
0.1
8.2
5
333
W82
ICPC
Abortion spontaneous
2.2
8.2
80
364
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
0.4
8.2
34
818
O35.9
ICD-10 Finland
Maternal care for (suspected) fetal abnormality and damage, unspecified
2.2
8.1
77
347
RD211
NOMESCO Finland
NA
1.8
8.1
125
683
LFE20
NOMESCO Finland
Suture of perineum
17.0
8.0
12
7
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
0.5
8.0
57
1131
O90.2
ICD-10 Finland
Haematoma of obstetric wound
8.8
8.0
16
18
103
Kela drug reimbursment
Diabetes, insulin-treated
0.6
7.8
166
2498
WZA10
SPAT
NA
0.2
7.8
9
403
MAA10
NOMESCO Finland
Biopsy of chorionic villus
3.8
7.8
31
81
SPAT1190
SPAT
Insertion or removal of intrauterine contraceptive device
1.3
7.8
539
4136
G03GA06
ATC
follitropin beta; parenteral
1.7
7.7
142
819
W94
ICPC
Puerperal mastitis
2.2
7.7
74
334
O81.0
ICD-10 Finland
Low forceps delivery
44.5
7.7
9
*
MAC99
NOMESCO Finland
Other augmentation of labor
44.5
7.7
9
*
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
0.4
7.7
38
853
SPAT1128
SPAT
Instruction of pelvic floor / sphincter exercises
2.3
7.7
69
304
SPAT1393
SPAT
Guidance to support interaction between parent and child
2.5
7.6
54
211
G03GA02
ATC
human menopausal gonadotrophin; parenteral
1.7
7.6
160
960
MAB10
NOMESCO Finland
External version
2.5
7.6
56
221
Z36
ICD-10 Finland
Antenatal screening
4.2
7.6
27
64
O34.1
ICD-10 Finland
Maternal care for tumour of corpus uteri
3.3
7.6
35
104
O24.9
ICD-10 Finland
Diabetes mellitus in pregnancy, unspecified
1.8
7.5
120
661
N05BA06
ATC
lorazepam; systemic, sublingual
0.4
7.5
28
700
MWE00
NOMESCO Finland
Reoperation for deep haemorrhage in obstetric surgery
7.9
7.5
16
20
SPAT1308
SPAT
Sexual health counselling
1.2
7.5
1286
11011
Z35.1
ICD-10 Finland
Supervision of pregnancy with history of abortive outcome
2.7
7.4
46
167
215
Kela drug reimbursment
Diabetes, non-insulin-treated
0.7
7.4
166
2465
O66.9
ICD-10 Finland
Obstructed labour, unspecified
79.3
7.4
8
*
J01FA10
ATC
azithromycin; systemic
1.2
7.4
2657
24341
W03
ICPC
Antepartum bleeding
2.2
7.4
73
338
O66.8
ICD-10 Finland
Other specified obstructed labour
+∞
7.3
7
*
O64.2
ICD-10 Finland
Obstructed labour due to face presentation
+∞
7.3
7
*
O62.3
ICD-10 Finland
Precipitate labour
+∞
7.3
7
*
O69.8
ICD-10 Finland
Labour and delivery complicated by other cord complications
+∞
7.3
7
*
H01CC02
ATC
cetrorelix; parenteral
2.9
7.2
42
145
SPAT1383
SPAT
Extensive health check-up at 4 years of age
2.0
7.2
83
409
Z36.2
ICD-10 Finland
Other antenatal screening based on amniocentesis
4.8
7.2
22
45
IHZ02
SPAT
NA
0.3
7.1
11
417
O26.6
ICD-10 Finland
Liver disorders in pregnancy, childbirth and the puerperium
1.9
7.1
99
521
MWC00
NOMESCO Finland
Reoperation for deep infection in obstetric surgery
29.7
7.1
9
*
R2110
NOMESCO Finland
Giving the first information
1.4
7.1
306
2170
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.2
7.1
1552
13591
E66.9
ICD-10 Finland
Obesity, unspecified
1.7
7.1
143
852
OAB31
SPAT
NA
6.5
7.0
17
26
OAB36
SPAT
NA
0.3
7.0
15
478
O20
ICD-10 Finland
Haemorrhage in early pregnancy
3.3
6.9
32
96
N71.0
ICD-10 Finland
Acute inflammatory disease of uterus
1.5
6.9
203
1333
H04AA01
ATC
glucagon; nasal, parenteral
0.4
6.8
35
774
CKC12
NOMESCO Finland
Photocoagulation of retina
0.3
6.8
16
489
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
1.3
6.8
630
5030
O36.5
ICD-10 Finland
Maternal care for poor fetal growth
1.6
6.7
182
1171
O03.1
ICD-10 Finland
Spontaneous abortion, Incomplete, complicated by delayed or excessive haemorrhage
1.8
6.7
106
585
J01CA08
ATC
pivmecillinam; oral
1.2
6.7
2094
18881
O71.8
ICD-10 Finland
Other specified obstetric trauma
39.5
6.7
8
*
O90.9
ICD-10 Finland
Complication of the puerperium, unspecified
4.5
6.7
22
49
O70.9
ICD-10 Finland
Perineal laceration during delivery, unspecified
22.3
6.6
9
*
ZYC02
SPAT
NA
0.5
6.6
40
838
O44.0
ICD-10 Finland
Placenta praevia specified as without haemorrhage
2.3
6.6
56
240
O32.0
ICD-10 Finland
Maternal care for unstable lie
3.1
6.5
33
106
F34.1
ICD-10 Finland
Dysthymia
0.5
6.5
63
1141
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
1.3
6.5
701
5701
J02AC01
ATC
fluconazole; systemic
1.2
6.5
2021
18206
O44.1
ICD-10 Finland
Placenta praevia with haemorrhage
2.8
6.4
38
135
R01AD01
ATC
beclometasone; nasal
1.3
6.4
520
4080
O71.7
ICD-10 Finland
Obstetric haematoma of pelvis
69.1
6.4
7
*
A10AE05
ATC
insulin detemir; parenteral
0.5
6.4
46
910
W45
ICPC
Pregnancy, Observ/health educat/advice/diet
2.7
6.3
41
151
T89
ICPC
Diabetes insulin dependent
0.5
6.3
44
879
O26.9
ICD-10 Finland
Pregnancy-related condition, unspecified
2.6
6.3
43
167
MBB96
NOMESCO Finland
Other manual procedure on delivered uterus
+∞
6.2
6
*
O71.1
ICD-10 Finland
Rupture of uterus during labour
+∞
6.2
6
*
O74.5
ICD-10 Finland
Spinal and epidural anaesthesia-induced headache during labour and delivery
+∞
6.2
6
*
SPAT1307
SPAT
Psychosocial counselling and guidance
1.3
6.2
430
3297
JHC00
NOMESCO Finland
Suture of anal sphincter
26.4
6.2
8
*
N76.0
ICD-10 Finland
Acute vaginitis
1.3
6.2
479
3737
O99.6
ICD-10 Finland
Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
2.1
6.1
68
330
N06AB10
ATC
escitalopram; oral
0.8
6.1
800
9273
W12
ICPC
Contraception intrauterine
1.2
6.1
882
7407

Mortality – FinRegistry

Association

Association between endpoint O15_LABOUR_OTHER and mortality.

Females

Parameter HR [95% CI] p-value
O15_LABOUR_OTHER 0.505 [0.38, 0.67] < 0.001
Birth year 0.995 [0.99, 1.0] 0.223

During the follow-up period (1.1.1998 — 31.12.2019), 66 out of 28717 females with O15_LABOUR_OTHER died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have O15_LABOUR_OTHER.

N-year risk Females Males
1 0.062% No data
5 0.287% No data
10 0.734% No data
15 1.451% No data
20 2.483% No data

Relationships between endpoints

Index endpoint: O15_LABOUR_OTHER – Other complications of labour and delivery, not elsewhere classified

GWS hits: 2

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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