Arnold-Chiari syndrome

Q17_ARNOLD_CHIARI_SYNDROME

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 Q07.0
  • Cause of death: ICD-10 Q07.0

2 out of 7 registries used, show all original rules.

347

4. Check minimum number of events

None

347

5. Include endpoints

None

347

6. Filter based on genotype QC (FinnGen only)

337

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 337 275 62
Unadjusted period prevalence (%) 0.08 0.10 0.03
Median age at first event (years) 32.63 32.91 31.40

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
347
Matched controls
3470
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q07.0
ICD-10 Finland
Arnold-Chiari syndrome
+∞
307.7
346
*
ABE50
NOMESCO Finland
Occipitocervical decompression
+∞
111.6
101
*
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
12.9
75.3
81
80
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
7.1
54.4
99
184
R51.80
ICD-10 Finland
Headache
5.2
50.4
160
490
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
17.4
50.3
43
28
G95.0
ICD-10 Finland
Syringomyelia and syringobulbia
244.5
42.9
43
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
6.0
39.6
83
174
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
5.6
29.9
64
135
N03AX12
ATC
[U] gabapentin; oral
4.4
28.7
86
240
R42
ICD-10 Finland
Dizziness and giddiness
3.9
27.8
104
340
AA1AD
NOMESCO Finland
CT of head and brain
3.9
26.5
100
328
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
20.6
21.7
32
17
G44.2
ICD-10 Finland
Tension-type headache
3.4
21.0
96
352
R20.2
ICD-10 Finland
Paraesthesia of skin
4.5
20.6
56
143
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
20.2
19.0
28
15
Z01.8
ICD-10 Finland
Other specified special examinations
3.0
18.0
103
428
N03AX16
ATC
[U] pregabalin
3.1
16.6
85
330
N06AX21
ATC
duloxetine; oral
3.4
16.3
66
222
NA7BG
NOMESCO Finland
Spine and spinal cord MRI examination with high intensity magnet
22.3
16.2
23
11
R51
ICD-10 Finland
Headache
4.0
15.1
46
127
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
3.2
14.9
69
251
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
3.2
14.1
63
224
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
4.4
13.9
37
92
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
3.6
13.8
50
156
TAB00
NOMESCO Finland
Lumbar puncture
4.4
13.4
35
86
N02AX02
ATC
tramadol; systemic, rectal
2.4
12.9
134
728
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.6
12.4
92
428
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.2
12.2
167
1015
A02BC02
ATC
pantoprazole; systemic
2.2
11.7
209
1405
G47.3
ICD-10 Finland
Sleep apnoea
2.6
10.3
66
284
L28
ICPC
Limited function/disability (L)
2.9
10.0
51
195
AAF20
NOMESCO Finland
Revision of shunt of ventricle of brain
56.6
9.7
11
*
L01
ICPC
Neck symptom/complaint
2.4
9.6
79
381
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.2
9.3
100
541
SPAT1310
SPAT
Counselling related to known health issue
2.1
9.3
136
828
A01
ICPC
Pain general/multiple sites
3.0
9.2
42
150
R96
ICPC
Asthma
3.1
9.1
41
146
N03AX11
ATC
topiramate; oral
4.5
9.0
22
51
M54.5
ICD-10 Finland
Low back pain
2.0
9.0
135
827
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.3
8.9
34
109
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
2.6
8.9
57
245
J45.9
ICD-10 Finland
Asthma, unspecified
2.3
8.8
78
388
N06AX16
ATC
venlafaxine; oral
2.4
8.7
68
320
N02BF01
ATC
gabapentin; oral
3.2
8.7
35
116
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
3.6
8.6
29
86
N03AE01
ATC
clonazepam; systemic
3.9
8.5
25
67
R52.2
ICD-10 Finland
Other chronic pain
4.8
8.5
19
41
M03BX02
ATC
tizanidine; oral
2.0
8.4
208
1504
TPH04
NOMESCO Finland
Cathetrisation of vein
2.3
8.3
69
333
A04
ICPC
Weakness/tiredness general
2.3
8.2
71
349
XKD00
NOMESCO Finland
Uroflowmetry
3.4
8.1
30
94
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
12.1
8.1
14
12
N06CA01
ATC
amitriptyline and psycholeptics; systemic
3.0
8.1
37
132
WX402
NOMESCO Finland
General anaesthesia
2.1
8.1
87
468
N01
ICPC
Headache
2.1
8.0
90
492
M03BX01
ATC
baclofen; systemic
8.1
8.0
17
22
M35.7
ICD-10 Finland
Hypermobility syndrome
7.2
7.9
18
26
A02BC01
ATC
omeprazole; systemic
2.1
7.8
92
512
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.8
7.8
40
153
XX9AW
NOMESCO Finland
Production of copy from X-ray picture
4.2
7.7
21
53
M54.4
ICD-10 Finland
Lumbago with sciatica
2.2
7.5
70
354
SPAT1263
SPAT
Sampling
1.9
7.5
163
1115
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
3.3
7.5
29
94
SPAT1153
SPAT
Removal of sutures
2.1
7.4
90
506
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
4.5
7.3
18
42
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
4.1
7.3
20
51
G43.9
ICD-10 Finland
Migraine, unspecified
2.5
7.2
48
209
R4120
NOMESCO Finland
Occupational therapy
2.9
7.2
34
124
N99
ICPC
Neurological disease other
20.5
7.2
10
5
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.4
7.2
52
236
N06AA09
ATC
amitriptyline; systemic
3.2
7.1
29
97
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
2.1
7.1
84
466
M54
ICD-10 Finland
Dorsalgia
2.3
7.1
57
271
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
3.2
7.1
28
92
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
6.1
7.0
18
31
A02BC05
ATC
esomeprazole; systemic
1.9
7.0
119
749
SPAT1301
SPAT
No procedures
1.9
6.9
116
726
R03AC02
ATC
salbutamol; inhalant
1.8
6.9
211
1589
G44.8
ICD-10 Finland
Other specified headache syndromes
6.9
6.9
16
24
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.6
6.9
40
163
O99.3
ICD-10 Finland
Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
3.8
6.9
21
58
UKC02
NOMESCO Finland
Cystoscopy
2.9
6.8
32
116
ZXE20
NOMESCO Finland
More than three and less than five hours
2.5
6.8
45
195
G91.9
ICD-10 Finland
Hydrocephalus, unspecified
40.9
6.8
8
*
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
17.1
6.8
10
6
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
3.3
6.7
25
79
R56.8
ICD-10 Finland
Other and unspecified convulsions
3.2
6.7
27
90
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
4.3
6.6
17
41
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
2.1
6.6
74
402
N02BE01
ATC
paracetamol; systemic, rectal
2.2
6.6
292
2464
WX882
NOMESCO Finland
High dependency care
3.8
6.6
20
55
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
7.6
6.5
14
19
AAF25
NOMESCO Finland
Removal of shunt of ventricle of brain
71.1
6.4
7
*
S06.0
ICD-10 Finland
Concussion
2.3
6.4
49
227
M54.3
ICD-10 Finland
Sciatica
3.7
6.4
20
56
G56.0
ICD-10 Finland
Carpal tunnel syndrome
2.4
6.4
47
215
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.8
6.3
179
1304
M79.6
ICD-10 Finland
Pain in limb
1.8
6.3
144
985
Z01.1
ICD-10 Finland
Examination of ears and hearing
2.3
6.3
53
257
SPAT1255
SPAT
Intravenous administration of medicine
3.5
6.2
21
62
N03AX09
ATC
lamotrigine; oral
2.8
6.2
31
117
D06
ICPC
Abdominal pain localized other
2.4
6.2
44
198
H53.2
ICD-10 Finland
Diplopia
5.4
6.1
17
33
UJF32
NOMESCO Finland
Coloscopy
2.1
6.1
63
332
P01AB01
ATC
metronidazole; oral, rectal
1.8
6.1
138
942

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
198
1099
2.87
20.52
8.8
5.6
1.22
1.22
mmol/l
0.57
173
955
183
1003
2.74
18.99
8.6
5.4
1.22
1.22
mmol/l
0.47
169
941
35
65
5.88
18.48
1.5
2.1
—
—
—
0
0
36
72
5.46
17.56
2.1
2.0
76.52
6.96
e6/l
1.02
27
54
36
72
5.46
17.56
2.1
2.1
137.82
143.03
e6/l
0.02
28
58
223
1428
2.57
15.72
6.1
4.0
5.96
6.24
mmol/l
1.78
212
1271
118
575
2.59
14.77
2.1
2.0
243.90
259.79
u/l
0.03
112
554
51
163
3.50
13.52
5.3
7.5
0.39
0.80
mmol/l
0.40
34
122
330
2699
5.55
13.30
15.7
9.5
3.92
3.90
mmol/l
0.65
323
2598
261
1878
2.57
13.17
6.0
6.2
73.04
77.89
u/l
1.04
249
1763
22
36
6.46
13.09
1.4
2.8
—
—
—
0
0
329
2699
5.22
12.87
15.8
9.4
139.68
139.55
mmol/l
0.58
322
2609
23
24
10.18
11.93
2.8
1.5
—
—
—
0
0
138
802
2.20
10.98
5.9
8.0
1.04
1.09
inr
0.67
40
280
146
868
2.18
10.97
4.2
4.5
38.20
37.33
g/l
1.64
133
824
295
2341
2.74
10.63
5.2
4.1
14.47
14.37
pmol/l
0.31
277
2164
264
1993
2.36
10.62
4.1
3.6
8.35
8.87
mm/h
0.33
251
1857
137
810
2.14
10.30
2.1
1.7
99.18
99.15
pmol/l
0.00
82
414
50
186
2.97
10.26
12.8
6.1
24.04
25.03
mmol/l
1.50
50
186
319
2682
3.35
9.45
5.9
4.7
1.62
1.79
mu/l
2.47
304
2521
78
384
2.33
9.05
1.4
1.5
127692757.46
433.10
pmol/l
0.49
65
341
177
1195
1.98
8.91
5.5
5.2
10.24
11.06
umol/l
0.21
165
1118
21
32
6.92
8.80
1.5
2.2
—
—
—
0
0
113
655
2.08
8.69
3.2
2.8
18.78
23.58
ng/l
0.21
54
298
62
281
2.47
8.62
1.9
2.0
382.56
389.32
nmol/l
0.09
54
263
117
694
2.03
8.41
3.0
2.4
49.51
59.75
u/l
2.39
107
644
210
1522
1.96
8.40
2.9
2.7
—
—
—
0
0
112
657
2.04
8.28
2.2
2.1
2.89
2.78
mg/l
0.23
94
572
48
205
2.56
7.53
9.0
7.6
—
—
—
0
0
61
292
2.32
7.47
1.2
1.2
—
—
—
0
0
266
2164
1.98
6.75
4.3
4.0
36.81
37.36
mmol/mol
0.49
247
2048
106
650
1.91
6.69
3.7
3.3
7.39
7.40
ph
0.45
20
109
80
445
2.04
6.69
1.5
1.4
18.99
20.71
nmol/l
0.50
70
382
129
843
1.84
6.67
2.7
2.0
—
—
—
0
0
289
2434
2.12
6.47
3.8
3.2
5.57
5.57
mmol/l
0.01
271
2262
94
562
1.92
6.36
1.8
2.0
0.80
0.99
mg/l
0.37
63
394
160
1139
1.75
6.06
2.9
2.4
70.69
72.24
nmol/l
0.31
151
1050
116
763
1.78
5.71
2.2
2.7
2.35
2.36
mmol/l
0.22
105
695
190
1440
1.71
5.59
6.5
5.6
0.04
0.04
e9/l
0.10
168
1242
48
235
2.21
5.54
8.9
4.2
—
—
—
0
0
18
52
3.60
5.53
1.3
1.8
1008.00
186.10
ug/l
0.63
11
44
189
1436
1.69
5.46
6.5
5.6
0.52
0.53
e9/l
0.48
168
1242
58
310
2.05
5.35
1.7
1.5
1061.58
1113.02
nmol/l
0.19
48
242
19
59
3.35
5.25
3.5
3.9
—
—
—
0
0
192
1486
1.65
5.00
7.1
6.1
0.20
0.18
e9/l
0.64
177
1314
13
24
5.58
4.96
1.5
1.7
—
—
—
0
0
334
3067
3.38
4.95
14.0
8.8
—
—
—
0
0
46
233
2.12
4.88
9.2
4.2
1.87
1.52
mmol/l
0.40
40
177
208
1651
1.65
4.84
8.7
8.0
3.76
3.93
e9/l
0.58
187
1421
321
2897
2.44
4.82
15.7
9.7
15.80
19.71
mg/l
1.98
276
2172
177
1351
1.63
4.81
7.9
6.1
—
—
—
0
0
22
81
2.83
4.61
6.4
2.5
0.50
0.68
%
1.60
22
81
192
1508
1.61
4.55
6.5
5.5
2.13
2.07
e9/l
0.37
173
1342
115
799
1.66
4.47
3.5
2.3
—
—
—
0
0
199
1581
1.61
4.46
3.3
2.8
69.38
57.82
ug/l
0.59
191
1479
174
1340
1.60
4.44
2.9
2.4
—
—
—
0
0
77
482
1.77
4.36
3.8
2.4
530.65
575.53
mosm/kgh2o
0.86
69
407
26
112
2.43
4.03
17.2
5.9
9.76
9.08
kpa
0.86
26
107
58
343
1.83
3.95
1.9
2.2
2.40
2.41
mmol/l
0.46
52
300
52
304
1.84
3.67
1.3
1.3
112.22
151.67
iu/ml
0.49
20
124
74
480
1.69
3.66
2.4
2.5
80.72
84.93
ug/g
0.08
54
367
173
1371
1.52
3.64
6.6
5.7
7.73
7.89
%
0.34
165
1291
73
474
1.68
3.60
4.3
3.5
—
—
—
0
0
126
937
1.54
3.54
1.4
1.4
0.61
2.10
u/ml
1.94
34
232
13
36
3.71
3.53
1.5
1.9
16.00
16.33
%
—
8
14
20
81
2.56
3.53
3.0
4.2
—
—
—
0
0
171
1359
1.51
3.51
6.6
5.5
2.70
2.78
%
0.23
163
1273
29
142
2.14
3.37
14.3
5.7
—
—
—
0
0
88
609
1.60
3.36
4.6
2.9
1.02
1.02
kg/l
0.32
12
87
103
742
1.55
3.30
5.1
3.1
0.00
0.00
estimate
0.50
37
296
164
1304
1.49
3.30
6.7
5.6
0.59
0.66
%
1.01
155
1220
51
308
1.77
3.24
1.6
1.7
—
—
—
0
0
23
104
2.30
3.23
3.1
3.1
117.94
129.28
ng/l
0.08
18
94
36
195
1.94
3.21
1.6
1.8
3.65
6.69
e9/l
1.23
30
173
30
152
2.07
3.21
3.4
3.4
—
—
—
0
0
42
240
1.85
3.19
2.1
2.4
23.50
31.89
u/l
1.23
36
195
226
1924
1.50
3.19
3.5
2.8
28.90
32.89
u/l
0.80
216
1838
76
515
1.61
3.15
1.3
1.3
13.36
23.71
iu/ml
1.62
24
150
29
148
2.05
3.05
3.5
3.6
1.23
1.22
mmol/l
0.24
23
127
75
512
1.59
3.01
4.0
2.2
5.85
9.36
e6/l
1.19
69
444
36
200
1.89
2.99
2.2
2.9
0.22
0.23
g/l
0.43
30
193
76
524
1.58
2.92
3.3
2.9
—
—
—
0
0
171
1396
1.44
2.88
4.7
3.1
0.05
0.00
estimate
0.49
39
303
174
1427
1.44
2.85
6.4
5.3
52.79
54.99
%
1.68
166
1347
164
1331
1.44
2.84
10.2
7.5
0.00
0.00
e9/l
0.29
131
1069
10
28
3.65
2.80
1.0
1.4
—
—
nmol/l
—
0
0
75
522
1.56
2.77
2.0
2.7
297.06
3907.92
umol/l
1.58
67
469
19
85
2.31
2.75
2.9
2.3
—
—
—
0
0
89
647
1.51
2.69
4.4
3.1
—
—
—
0
0
95
701
1.49
2.67
4.3
2.7
—
—
—
0
0
8
20
4.07
2.58
7.7
4.8
1.86
2.14
ug/l
—
8
20
10
31
3.29
2.54
1.3
4.0
—
—
—
0
0
173
1438
1.40
2.52
6.6
5.5
32.57
31.15
%
0.98
164
1362
92
682
1.47
2.51
4.6
2.7
0.18
0.32
e6/l
0.60
72
502
107
817
1.45
2.51
1.8
1.5
1.76
1.96
g/l
1.23
70
475
11
37
3.04
2.51
10.5
2.6
—
—
—
0
0
171
1421
1.40
2.49
4.9
3.1
0.00
0.00
estimate
-0.00
38
283
32
184
1.81
2.42
2.3
3.8
—
—
—
0
0
16
71
2.31
2.38
2.4
2.3
—
—
—
0
0
5
8
6.32
2.38
2.6
3.0
55.00
56.63
nmol/l
—
5
8
168
1400
1.39
2.37
6.4
4.3
0.00
0.00
estimate
0.50
34
298
278
2529
1.50
2.36
3.8
3.5
2.80
2.81
mmol/l
0.10
261
2391
56
378
1.57
2.35
3.7
2.6
5.33
3.50
e6/l
0.59
32
194
52
345
1.60
2.35
2.5
2.3
4430.24
3471.72
u/l
0.10
14
151
9
29
3.16
2.24
12.7
2.5
70.22
62.47
%
—
9
29
26
144
1.87
2.21
1.3
1.4
—
—
—
0
0
6
14
4.34
2.16
2.0
2.9
1.37
2.53
nmol/l
—
6
14
40
254
1.65
2.16
1.4
1.5
18.87
19.94
iu/l
0.08
33
208
141
1156
1.37
2.14
4.3
2.9
5.84
5.99
ph
0.39
19
116
16
75
2.19
2.12
7.6
7.8
—
—
—
0
0
11
43
2.61
2.10
1.1
1.4
—
—
—
0
0
98
760
1.40
2.07
4.9
2.7
17.07
64.67
e6/l
2.48
77
566
30
178
1.75
2.06
6.2
3.9
0.00
0.04
%
—
7
45
120
964
1.37
2.05
5.2
3.2
61.11
55.70
e6/l
0.04
85
611
225
1996
1.36
2.00
5.6
3.8
—
—
—
0
0
31
189
1.70
1.95
6.0
3.9
0.00
0.65
%
—
7
57
83
632
1.41
1.94
3.7
3.4
7.02
8.26
mmol/l
1.47
75
560
9
34
2.69
1.88
1.4
1.2
—
—
—
0
0
21
115
1.88
1.87
1.7
1.7
—
—
—
0
0
273
2511
1.41
1.86
3.5
3.3
4.61
4.68
mmol/l
0.58
258
2389
59
425
1.47
1.85
1.4
1.4
280.00
512.64
titre
—
8
87
15
73
2.10
1.83
1.8
1.5
89.00
116.21
u/ml
—
7
13
33
209
1.64
1.82
1.5
1.4
—
—
—
0
0
261
2388
1.38
1.79
3.2
2.9
1.16
1.18
mmol/l
0.15
244
2249
8
30
2.70
1.73
2.1
2.1
37.87
40.33
%
—
8
30
17
89
1.96
1.73
2.5
1.4
—
—
—
0
0
7
24
2.95
1.73
1.3
1.5
5.83
5.61
mmol/l
—
7
18
5
13
3.89
1.72
2.6
1.5
0.20
0.22
e9/l
—
5
13
80
620
1.38
1.68
1.5
1.6
—
—
—
0
0
13
62
2.14
1.67
1.0
1.3
—
—
—
0
0
8
31
2.62
1.67
1.1
1.4
—
—
—
0
0
29
182
1.65
1.66
3.5
3.8
0.00
0.64
%
—
7
50
7
25
2.84
1.66
1.6
1.4
93.23
92.00
%
—
7
25
31
199
1.61
1.63
1.4
1.3
—
—
—
0
0
5
14
3.61
1.62
1.0
1.1
1562.80
1580.71
miu/ml
—
5
14
270
2499
1.36
1.60
3.5
3.2
1.48
1.50
mmol/l
0.32
253
2366
90
717
1.34
1.58
6.7
6.5
—
—
—
0
0
50
361
1.45
1.56
3.2
2.8
52.62
335.36
ng/l
2.25
24
192
20
115
1.78
1.56
1.1
1.1
—
—
—
0
0
28
178
1.62
1.54
1.3
1.2
—
—
—
0
0
15
79
1.94
1.52
4.9
10.7
—
—
—
0
0
40
278
1.50
1.51
2.2
1.6
—
—
—
0
0
44
312
1.47
1.51
1.8
1.5
—
—
—
0
0
15
80
1.91
1.47
1.8
1.5
—
—
—
0
0
40
280
1.48
1.46
2.2
1.6
—
—
—
0
0
40
281
1.48
1.44
2.2
1.6
—
—
—
0
0
6
22
2.76
1.44
1.3
2.2
—
—
—
0
0
9
40
2.28
1.41
1.8
1.7
—
—
—
0
0
21
128
1.68
1.36
2.9
2.0
—
—
—
0
0
14
75
1.90
1.36
2.6
2.3
—
—
—
0
0
9
42
2.17
1.34
1.1
1.0
—
—
—
0
0
15
83
1.84
1.33
1.0
1.0
—
—
—
0
0
15
83
1.84
1.33
1.0
1.0
—
—
—
0
0
66
517
1.34
1.30
1.3
1.3
1.76
11.43
u/ml
3.75
23
207
8
34
2.38
1.30
2.1
2.4
1.90
1.48
e9/l
—
8
27
5
18
2.80
1.29
22.0
3.2
13.06
11.32
%
—
5
18
17
100
1.74
1.26
1.8
2.0
9.61
6.50
iu/l
—
7
35
8
36
2.25
1.25
3.4
3.9
33.37
35.08
umol/l
—
8
36
6
25
2.42
1.25
1.7
2.6
—
—
—
0
0
9
45
2.03
1.24
1.3
1.9
—
—
—
0
0
5
19
2.65
1.22
1.4
1.6
0.77
0.95
g/l
—
5
19
24
158
1.56
1.18
2.9
2.0
—
—
—
0
0
38
277
1.42
1.16
2.3
1.6
—
—
—
0
0
5
20
2.52
1.15
1.8
2.7
—
—
—
0
0
5
20
2.52
1.15
1.2
1.5
683.00
374.60
mu/l
—
5
20
5
20
2.52
1.15
1.2
1.5
75.20
75.80
%
—
5
20
122
1055
1.24
1.11
1.9
1.9
—
—
—
0
0
286
2713
1.31
1.11
17.9
12.3
332.58
333.07
g/l
0.42
286
2696
12
66
1.85
1.10
1.8
1.8
—
—
—
0
0
12
66
1.85
1.10
1.1
1.2
—
—
—
0
0
29
404
0.69
1.10
1.2
1.3
—
—
—
0
0
31
222
1.44
1.05
2.3
1.6
—
—
—
0
0
13
75
1.76
1.04
1.1
1.1
—
—
—
0
0
47
363
1.34
1.03
1.2
1.2
—
—
—
0
0
25
174
1.47
0.98
1.1
1.1
—
—
—
0
0
0
31
0.00
0.97
0.0
1.3
—
—
—
0
0
14
219
0.62
0.94
1.4
1.4
—
—
—
0
0
25
176
1.45
0.93
1.4
1.7
7.01
9.66
u/l
1.02
17
140
8
43
1.88
0.88
2.4
1.7
4.63
4.97
kpa
—
8
43
8
43
1.88
0.88
2.4
1.7
9.68
9.54
kpa
—
8
43
6
30
2.02
0.87
1.0
1.1
—
—
—
0
0
54
437
1.28
0.87
3.7
3.6
1166.30
78.87
mg/l
0.46
38
294
15
96
1.59
0.86
1.8
1.6
242.67
211.25
u/ml
—
9
56
15
225
0.65
0.85
1.4
1.5
—
—
—
0
0
6
31
1.95
0.85
2.3
2.1
—
—
—
0
0
95
823
1.21
0.84
4.2
2.6
—
—
—
0
0
16
105
1.55
0.83
1.4
1.5
—
—
—
0
0
8
47
1.72
0.81
2.0
1.7
12.86
13.19
%
—
8
47
6
33
1.83
0.79
4.5
2.5
1.42
1.17
mmol/l
—
6
33
6
33
1.83
0.79
1.5
1.3
—
—
—
0
0
14
90
1.58
0.79
15.9
8.2
1.15
1.16
mg/l
0.03
14
85
15
219
0.67
0.76
1.4
1.4
—
—
—
0
0
17
116
1.49
0.75
1.4
1.2
—
—
—
0
0
55
455
1.25
0.75
4.0
4.1
4.33
12.50
mg/mmol
1.40
35
295
36
282
1.31
0.75
1.4
1.2
—
—
—
0
0
25
188
1.36
0.68
2.6
2.0
—
—
—
0
0
33
261
1.29
0.65
2.3
1.6
—
—
—
0
0
16
112
1.45
0.64
4.1
1.9
0.14
0.10
e6/l
0.18
16
106
0
21
0.00
0.60
0.0
3.0
—
45.50
—
0
10
0
22
0.00
0.59
0.0
1.1
—
—
—
0
0
47
400
1.20
0.52
1.6
2.1
—
—
—
0
0
14
101
1.40
0.50
3.8
2.6
—
—
—
0
0
12
85
1.43
0.47
1.3
1.2
—
1.94
—
0
5
7
49
1.44
0.46
1.3
1.3
—
—
—
0
0
29
239
1.23
0.44
1.3
1.3
—
—
—
0
0
5
31
1.62
0.43
2.0
2.1
1433.60
747.77
e6/l
—
5
31
59
522
1.16
0.43
1.9
1.6
—
—
—
0
0
5
32
1.57
0.42
4.6
2.5
5.84
6.63
mmol/l
—
5
32
5
32
1.57
0.42
2.2
2.3
970.00
594.44
e6/l
—
5
25
5
32
1.57
0.42
2.2
2.3
0.25
0.20
e9/l
—
5
25
14
105
1.35
0.41
1.4
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
7
55
1.28
0.30
2.7
2.7
—
—
—
0
0
90
963
0.91
0.29
1.9
1.8
—
—
—
0
0
32
280
1.16
0.28
4.4
3.1
—
—
—
0
0
26
225
1.17
0.27
3.9
3.8
4.64
4.84
pmol/l
0.43
26
202
12
95
1.27
0.26
2.3
5.1
0.12
0.30
g/l
—
5
52
23
199
1.17
0.24
1.4
1.4
218.08
276.25
miu/ml
0.31
12
96
20
171
1.18
0.24
1.7
1.4
—
—
—
0
0
5
38
1.32
0.23
1.0
1.3
—
—
—
0
0
80
849
0.92
0.22
1.8
1.7
—
—
—
0
0
5
41
1.22
0.22
7.6
3.7
—
—
—
0
0
21
241
0.86
0.22
1.5
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
26.22
—
0
10
115
1099
1.07
0.21
1.8
1.8
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
72.92
—
0
13
0
14
0.00
0.20
0.0
9.6
—
—
—
0
0
0
14
0.00
0.20
0.0
1.5
—
—
—
0
0
6
53
1.13
0.19
3.8
3.8
4.04
4.18
e9/l
—
6
53
6
53
1.13
0.19
4.0
3.9
55.17
57.11
%
—
6
53
36
329
1.11
0.18
1.6
1.5
—
—
—
0
0
7
61
1.15
0.17
1.4
2.0
6.93
9.20
mg/l
—
7
56
22
244
0.89
0.15
1.6
1.6
—
—
—
0
0
9
81
1.11
0.15
1.4
1.2
—
—
—
0
0
16
178
0.89
0.11
2.2
2.1
16.14
48.19
u/ml
1.43
16
170
5
48
1.04
0.09
1.6
1.6
0.16
7.82
ug/l
—
5
43
7
64
1.10
0.08
1.3
1.5
—
—
—
0
0
9
84
1.07
0.07
1.0
1.2
—
—
—
0
0
9
85
1.06
0.07
1.1
1.4
—
—
—
0
0
21
197
1.07
0.06
1.1
1.1
—
—
—
0
0
102
1002
1.03
0.05
2.0
2.1
—
—
—
0
0
63
614
1.03
0.05
1.6
1.6
1.33
1.32
mmol/l
0.05
57
546
31
298
1.04
0.04
1.1
1.2
—
—
—
0
0
23
222
1.04
0.02
1.0
1.2
—
105.63
—
0
8
120
1190
1.01
0.02
2.1
2.1
—
—
—
0
0
25
253
0.99
0.00
1.4
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.8
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.6
—
31.40
—
0
5
0
6
0.00
-0.00
0.0
5.7
—
—
—
0
0
8
81
0.99
-0.00
2.0
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
56
0.89
-0.00
1.6
1.1
—
—
—
0
0
5
54
0.92
-0.00
1.0
2.1
1.33
0.87
nmol/l
—
5
49
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.9
—
—
—
0
0
6
65
0.92
-0.00
1.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: Q17_ARNOLD_CHIARI_SYNDROME – Arnold-Chiari syndrome

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).