brain glioblastoma: A WHO grade IV malignant astrocytic tumor that arises from the brain, usually the cerebral hemispheres. It is characterized by the presence of poorly differentiated astrocytes, cellular polymorphism, nuclear atypia, and increased mitotic activity. The prognosis is poor.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditions
|
497 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
497 |
4. Check minimum number of eventsNone |
497 |
5. Include endpoints |
497 |
6. Filter based on genotype QC (FinnGen only) |
467 |
Control definitions (FinnGen only)
- Control exclude
- C3_CANCER, C3_CANCER_WIDE
- Control conditions
- not HLP_C3_GBM
Extra metadata
- Level in the ICD hierarchy
- C
- First used in FinnGen datafreeze
- DF8
Similar endpoints
↥List of similar endpoints to
Brain glioblastoma
based on the number of shared cases.
Similar with more cases:
- Brain glioblastoma and astrocytoma
- Malignant neoplasm of brain
- Malignant neoplasm of eye, brain and central nervous system
- Malignant neoplasm of brain, including Hilmo
- Solid cancers, helper endpoint
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 467 | 187 | 280 |
| Unadjusted period prevalence (%) | 0.10 | 0.07 | 0.13 |
| Median age at first event (years) | 65.42 | 65.77 | 65.18 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 497
- Matched controls
- 4970
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
62.1
317.5
185
47
130
Kela drug reimbursment
Malignant tumour
+∞
307.7
394
*
N03AX14
ATC
levetiracetam; systemic
121.4
307.7
272
49
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
39.5
307.7
283
161
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
37.5
307.7
237
118
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
2162.6
307.7
373
7
Z51.5
ICD-10 Finland
Palliative care
66.4
307.7
242
70
L01AX03
ATC
temozolomide; systemic
+∞
307.7
349
*
A03FA01
ATC
metoclopramide; systemic, rectal
29.8
307.7
324
294
H02AB02
ATC
dexamethasone; systemic
1884.1
307.7
444
22
A04AA01
ATC
ondansetron; systemic, rectal
55.2
268.5
159
42
WF002
NOMESCO Finland
Radical radiotherapy
967.0
244.3
220
*
ZXC95
NOMESCO Finland
Use of surgical navigator
92.7
227.0
120
17
A04AA02
ATC
granisetron; systemic, transdermal
3566.0
224.7
200
*
XX3DW
NOMESCO Finland
Time consuming IT work
25.5
219.6
172
101
C71.23
ICD-10 Finland
Malignant tumor of temporal lobe grade IV glioma
+∞
202.3
180
*
D43.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, supratentorial
578.1
195.6
182
5
9440/3-C71.9
ICD-O-3
Glioblastoma, NOS, of brain, NOS
+∞
189.0
169
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
171.0
154
*
C71.2
ICD-10 Finland
Malignant neoplasm: Temporal lobe
+∞
167.4
151
*
C71.13
ICD-10 Finland
Malignant tumor of frontal lobe grade IV glioma
+∞
163.9
148
*
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
28.7
160.8
114
51
AAG50
NOMESCO Finland
Stereotactic intracranial radiotherapy
900.3
142.4
133
*
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
+∞
141.6
129
*
C71.1
ICD-10 Finland
Malignant neoplasm: Frontal lobe
+∞
137.0
125
*
9440/3-C71.2
ICD-O-3
Glioblastoma, NOS, of temporal lobe
+∞
132.4
121
*
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
27.3
129.2
92
41
C71.90
ICD-10 Finland
Malignant tumor in unspecified localization in the brain without histology
+∞
124.3
114
*
C71.20
ICD-10 Finland
Malignant tumor in temporal lobe without histology
+∞
123.2
113
*
N03AX18
ATC
lacosamide; systemic
52.4
117.0
68
15
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
115.2
106
*
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
24.1
111.4
83
41
9440/3-C71.1
ICD-O-3
Glioblastoma, NOS, of frontal lobe
+∞
103.9
96
*
C71.10
ICD-10 Finland
Malignant tumor in frontal lobe without histology
+∞
102.8
95
*
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
12.4
101.8
112
114
AA1AD
NOMESCO Finland
CT of head and brain
6.4
95.6
297
932
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
288.9
95.2
94
*
C71.33
ICD-10 Finland
Malignant tumor of parietal lobe grade IV glioma
+∞
94.9
88
*
WX882
NOMESCO Finland
High dependency care
20.9
91.5
72
40
AAG00
NOMESCO Finland
Stereotactic intracranial biopsy
+∞
86.0
80
*
N02AA05
ATC
oxycodone; systemic
6.6
83.5
175
376
YX8VG
NOMESCO Finland
Stereotactic MRI exmaination with high intensity magnet for dose design of radiotherapy
906.4
80.8
77
*
ZX095
NOMESCO Finland
Combined chemoradiotherapy
+∞
79.3
74
*
N03AF02
ATC
oxcarbazepine; oral
14.3
77.9
75
61
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
6.0
77.4
186
451
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
298.2
76.8
76
*
N05CD08
ATC
midazolam; nasal, systemic
16.7
76.4
67
46
YX8BD
NOMESCO Finland
Stereotactic extensive CT examination for dose design of radiotherapy
408.4
72.7
71
*
C71.3
ICD-10 Finland
Malignant neoplasm: Parietal lobe
+∞
70.5
66
*
C71.30
ICD-10 Finland
Malignant tumor in parietal lobe without histology
+∞
68.3
64
*
AA1BD
NOMESCO Finland
Extensive CT of head and brain
17.0
60.5
52
34
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
335.7
59.7
59
*
N74
ICPC
Malignant neoplasm nervous system
639.6
59.0
57
*
C71.83
ICD-10 Finland
Overall malignant tumor of the brain grade IV glioma
+∞
58.5
55
*
R56.8
ICD-10 Finland
Other and unspecified convulsions
7.9
57.5
87
130
ZX050
NOMESCO Finland
Stereotactic radiotherapy
+∞
57.4
54
*
WZC30
NOMESCO Finland
Teaching
5.5
57.3
136
318
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
5.9
54.6
116
245
WZC00
NOMESCO Finland
Treatment plan or consultation
4.2
53.2
231
860
9440/3-C71.3
ICD-O-3
Glioblastoma, NOS, of parietal lobe
+∞
53.1
50
*
WX402
NOMESCO Finland
General anaesthesia
4.5
50.4
160
471
D43.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Central nervous system, unspecified
539.4
50.3
49
*
D43.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, unspecified
514.9
48.2
47
*
C71.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of brain
+∞
47.7
45
*
ZXM40
NOMESCO Finland
Use of fluorescent substance
490.6
46.1
45
*
ZXC40
NOMESCO Finland
Use of ultrasound
88.5
43.7
48
6
C71.99
ICD-10 Finland
Malignant tumor in unspecified localization in the brain other or unspecified histology
+∞
43.4
41
*
JN4BD
NOMESCO Finland
Extensive body CT
7.3
42.9
68
106
G40.9
ICD-10 Finland
Epilepsy, unspecified
7.7
39.9
59
85
YA1VG
NOMESCO Finland
MRI examination of head and neck with high intesity magnet for dose design of radiotherapy
148.6
39.4
41
*
A28
ICPC
Limited function/disability NOS
3.9
38.9
152
510
R4120
NOMESCO Finland
Occupational therapy
5.9
37.7
74
143
ZX070
NOMESCO Finland
Intensity modified radiotherapy
395.5
37.5
37
*
JN4AD
NOMESCO Finland
Body CT examination
6.4
36.5
65
114
A79
ICPC
Malignancy NOS
+∞
35.9
34
*
C79.30
ICD-10 Finland
Secondary malignant tumor of the cerebrum
+∞
35.9
34
*
A02BC02
ATC
pantoprazole; systemic
4.2
35.5
409
2623
ZXE20
NOMESCO Finland
More than three and less than five hours
4.1
34.6
113
332
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
33.7
32
*
A98
ICPC
Health maint/preventive medicine
0.3
33.3
343
4400
C71.29
ICD-10 Finland
Malignant tumor in temporal lobe other or unspecified histology
+∞
32.7
31
*
C71.93
ICD-10 Finland
Malignant tumor in an unspecified localization in the brain grade IV glioma
+∞
32.7
31
*
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
9.7
31.6
38
42
H53.4
ICD-10 Finland
Visual field defects
10.4
30.7
35
36
C71.43
ICD-10 Finland
Malignant tumor of the occipital lobe grade IV glioma
+∞
30.5
29
*
WX872
NOMESCO Finland
Intensive care
5.2
29.9
66
141
ZX090
NOMESCO Finland
Other technic of radiotherapy
85.4
29.1
32
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
3.3
26.4
122
445
C71.80
ICD-10 Finland
Overall malignant tumor of the brain without histology
+∞
26.3
25
*
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
25.8
26.1
36
15
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.1
26.0
136
534
B01AB10
ATC
tinzaparin; parenteral
4.5
25.9
69
172
N05CF01
ATC
zopiclone; oral
2.7
25.5
216
1096
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
45.4
24.8
30
7
WX408
NOMESCO Finland
General anesthesy, balanced
2.9
24.5
154
667
R4110
NOMESCO Finland
Physiotherapy
2.8
23.9
172
799
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
251.6
23.9
24
*
C71.9
ICD-10 Finland
Malignant neoplasm: Brain, unspecified
+∞
23.1
22
*
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
+∞
23.1
22
*
TPH04
NOMESCO Finland
Cathetrisation of vein
2.8
22.3
141
610
AAA10
NOMESCO Finland
Biopsy through craniotomy
+∞
22.0
21
*
C71.40
ICD-10 Finland
Malignant tumor of the occipital lobe without histology
+∞
22.0
21
*
9440/3-C71.0
ICD-O-3
Glioblastoma, NOS, of cerebrum
+∞
22.0
21
*
XA800
NOMESCO Finland
Neuropsychological investigation
5.5
21.6
44
87
WX704
NOMESCO Finland
Intubation
4.4
21.6
58
145
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
8.3
21.5
29
37
9440/3-C71.8
ICD-O-3
Glioblastoma, NOS, of overlapping lesion of brain
+∞
21.0
20
*
C71.00
ICD-10 Finland
Malignant tumor of the cerebrum except lobes and ventricles without histology
+∞
21.0
20
*
C71.03
ICD-10 Finland
Malignant tumor of cerebellum except lobes and ventricles grade IV glioma
+∞
19.9
19
*
C71.19
ICD-10 Finland
Malignant tumor of frontal lobe other or unspecified histology
+∞
19.9
19
*
N76
ICPC
Neoplasm nervous system unspecified
+∞
19.9
19
*
C71.4
ICD-10 Finland
Malignant neoplasm: Occipital lobe
+∞
18.9
18
*
G40.10
ICD-10 Finland
Simple partial seizures
40.1
18.7
23
6
D43.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, infratentorial
197.1
18.7
19
*
G41.9
ICD-10 Finland
Status epilepticus, unspecified
31.4
18.5
24
8
H02AB04
ATC
methylprednisolone; systemic
2.9
18.5
101
400
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
20.3
18.4
27
14
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
69.2
17.8
20
*
R90.0
ICD-10 Finland
Intracranial space-occupying lesion
+∞
17.8
17
*
C71.22
ICD-10 Finland
Malignant tumor of temporal lobe grade III glioma
+∞
17.8
17
*
WC105
NOMESCO Finland
Simple cytostatic therapy of local tumor recidive
186.4
17.6
18
*
R90.8
ICD-10 Finland
Other abnormal findings on diagnostic imaging of central nervous system
17.8
17.6
27
16
WF049
NOMESCO Finland
Radiotherapy of metastasis
175.7
16.6
17
*
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
21.8
16.1
23
11
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
15.7
15
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
165.0
15.6
16
*
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
0.1
15.1
12
794
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
7.0
15.0
23
34
N05BA04
ATC
oxazepam; oral
2.3
14.8
150
791
WF029
NOMESCO Finland
Radiotherapy of local residive tumor
+∞
14.7
14
*
115
Kela drug reimbursment
Breast cancer
+∞
14.7
14
*
9440/3-C71.4
ICD-O-3
Glioblastoma, NOS, of occipital lobe
+∞
14.7
14
*
N03AB02
ATC
phenytoin; systemic
10.5
13.6
26
26
C71.12
ICD-10 Finland
Malignant tumor of frontal lobe grade III glioma
+∞
13.6
13
*
XX9BW
NOMESCO Finland
Submitting image material and/or investigation material to authority or other institution
16.8
13.6
21
13
SPAT1245
SPAT
Provision of support and information to patient’s family members
4.6
13.5
33
76
R4130
NOMESCO Finland
Speech therapy
5.8
13.5
25
45
C10AA07
ATC
rosuvastatin; oral
0.3
13.2
51
1267
G40.19
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
15.6
13.2
21
14
A10AB05
ATC
insulin aspart; parenteral
3.1
12.9
56
193
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
14.6
12.9
21
15
C71.0
ICD-10 Finland
Malignant neoplasm: Cerebrum, except lobes and ventricles
+∞
12.5
12
*
PJA12
NOMESCO Finland
Sentinel node biopsy
133.2
12.5
13
*
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
3.7
12.4
41
119
ZXE30
NOMESCO Finland
More than five and less than seven hours
4.6
12.3
30
69
WW200, ,
SPAT
0.2
12.3
19
798
N03AG01
ATC
valproic acid; systemic, rectal
3.3
11.9
46
148
TPH07
NOMESCO Finland
Cathetrisation of artery
2.8
11.7
65
257
WX110
NOMESCO Finland
Infiltration anesthesia
2.0
11.7
345
2626
ZXD10
NOMESCO Finland
Scheduled procedure
2.0
11.7
194
1216
G93.6
ICD-10 Finland
Cerebral oedema
+∞
11.5
11
*
YX9BD
NOMESCO Finland
Other extensive CT eamination for dose design of radiotherapy
+∞
11.5
11
*
C71.39
ICD-10 Finland
Malignant tumor of parietal lobe other or unspecified histology
+∞
11.5
11
*
C71.21
ICD-10 Finland
Malignant tumor of temporal lobe grade II glioma
+∞
11.5
11
*
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.7
11.3
68
280
N05BA09
ATC
clobazam; oral
17.6
11.3
17
10
WX725
NOMESCO Finland
Noninvasive ventilation
3.5
10.9
38
114
D69.5
ICD-10 Finland
Secondary thrombocytopenia
+∞
10.4
10
*
C71
ICD-10 Finland
Malignant neoplasm of brain
+∞
10.4
10
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
10.4
10
*
AWB00
NOMESCO Finland
Reoperation for superficial infection in surgery of the nervous system
+∞
10.4
10
*
GD1AA, ,
SPAT
0.1
10.3
*
312
G40.11
ICD-10 Finland
Simple partial epileptic seizure that develops into a complex partial seizure
23.9
10.3
14
6
M79.6
ICD-10 Finland
Pain in limb
0.4
10.3
77
1466
WX892
NOMESCO Finland
Monitored bed care
2.8
10.0
52
198
XF400
NOMESCO Finland
ECG with 12 standard connections
2.2
10.0
96
487
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
0.3
9.8
32
885
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
15.4
9.6
15
10
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
101.9
9.4
10
*
L02BA01
ATC
tamoxifen; oral
101.9
9.4
10
*
I26.0
ICD-10 Finland
Pulmonary embolism with mention of acute cor pulmonale
5.3
9.4
19
37
C71.32
ICD-10 Finland
Malignant tumor of parietal lobe grade III glioma
+∞
9.4
9
*
C71.01
ICD-10 Finland
Malignant tumor of cerebellum except lobes and ventricles grade II glioma
+∞
9.4
9
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
9.4
9
*
M25.5
ICD-10 Finland
Pain in joint
0.4
9.3
47
1061
EB1VA, ,
NOMESCO Finland
0.1
9.3
*
332
TKC20
NOMESCO Finland
Catheterisation of bladder
2.9
9.3
46
171
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
0.4
9.1
41
975
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.9
9.1
45
167
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
0.4
8.9
54
1130
C10AX09
ATC
ezetimibe; oral
0.2
8.7
15
599
H02AB09
ATC
hydrocortisone; systemic
7.1
8.6
20
29
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
0.5
8.5
83
1460
N05BA06
ATC
lorazepam; systemic, sublingual
3.1
8.4
36
123
ZX080
NOMESCO Finland
Image guided radiotherapy
+∞
8.4
8
*
WB401
NOMESCO Finland
Simple antibody therapy of primary tumour
+∞
8.4
8
*
C50.40
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, no histological veryfication
+∞
8.4
8
*
AA5BD
NOMESCO Finland
CT of cerebral ischaemia
4.0
8.2
23
59
HA1AA
NOMESCO Finland
X-ray mammography
4.5
8.2
20
46
I61.9
ICD-10 Finland
Intracerebral haemorrhage, unspecified
6.5
8.1
20
32
XA400
NOMESCO Finland
EEG
15.3
7.7
12
8
WPA10
NOMESCO Finland
Proactive palliative care treatment plan
45.7
7.7
9
*
YX8AD
NOMESCO Finland
Stereotactic CT examination for dose design of radiotherapy
45.7
7.7
9
*
SPAT1109
SPAT
Analgesia with portable analgesic pump
45.7
7.7
9
*
R41.0
ICD-10 Finland
Disorientation, unspecified
3.6
7.6
25
72
HAB40
NOMESCO Finland
Wedge excision of mammary gland
18.7
7.6
11
6
SAA02
NOMESCO Finland
Basic examination of mouth
0.6
7.5
173
2383
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
7.5
167
1115
G41.2
ICD-10 Finland
Complex partial status epilepticus
81.3
7.4
8
*
Z25.8
ICD-10 Finland
Need for immunization against other specified single viral diseases
0.2
7.4
5
305
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.6
7.4
43
174
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
2.6
7.4
43
174
C71.50
ICD-10 Finland
Malignant tumor of cerebral ventricle without histology
+∞
7.3
7
*
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
7.3
7
*
OAA41
NOMESCO Finland
Health check based on individual needs
+∞
7.3
7
*
Z51.0
ICD-10 Finland
Radiotherapy session
+∞
7.3
7
*
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
+∞
7.3
7
*
L02BG04
ATC
letrozole; oral
16.0
7.3
11
7
C07AB07
ATC
bisoprolol; oral
0.6
7.3
137
1995
Z76.0
ICD-10 Finland
Issue of repeat prescription
0.3
7.1
26
689
R03BB04
ATC
tiotropium bromide; inhalant
0.2
7.0
7
335
206
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
0.3
7.0
26
685
L17
ICPC
Foot/toe symptom/complaint
0.4
7.0
46
946
Z02.4
ICD-10 Finland
Examination for driving licence
0.5
7.0
56
1069
A10BK03
ATC
empagliflozin; oral
0.2
7.0
6
314
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
3.4
6.9
25
77
N03AX23
ATC
brivaracetam; systemic
14.0
6.9
11
8
SAA01
NOMESCO Finland
Simple examination of mouth
0.6
6.9
212
2740
H25.1
ICD-10 Finland
Senile nuclear cataract
0.4
6.9
47
951
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
3.2
6.8
27
88
Z73.3
ICD-10 Finland
Stress, not elsewhere classified
11.1
6.8
12
11
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
9.5
6.8
13
14
N02BF01
ATC
gabapentin; oral
0.1
6.8
*
224
ZSA00
NOMESCO Finland
Procedure related to previous procedure classified in chapter A
17.0
6.8
10
6
OAB42, ,
SPAT
0.1
6.7
*
266
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
3.1
6.6
27
90
L03
ICPC
Low back symptom/complaint
0.4
6.6
40
849
B01AB05
ATC
enoxaparin; parenteral
1.7
6.5
139
913
SPAT1290
SPAT
Preparation of deceased person
70.7
6.4
7
*
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
0.3
6.4
19
562
SDA03
NOMESCO Finland
Periodontal treatment
0.5
6.4
78
1300
M54.4
ICD-10 Finland
Lumbago with sciatica
0.3
6.3
19
558
I25.1
ICD-10 Finland
Atherosclerotic heart disease
0.4
6.3
41
850
C71.11
ICD-10 Finland
Malignant tumor of frontal lobe grade II glioma
+∞
6.3
6
*
1CD02, ,
NOMESCO Finland
+∞
6.3
6
*
C50.21
ICD-10 Finland
Malignant tumor of the upper inner quadrant of the mammary gland,ductal tumor
+∞
6.3
6
*
C10AA05
ATC
atorvastatin; oral
0.6
6.2
114
1696
THW99
NOMESCO Finland
Other minor procedure in surgery of mammary gland
27.0
6.2
8
*
SPAT1229
SPAT
Assessment of need for aid
2.4
6.1
42
184
PA6AD
NOMESCO Finland
CT of neck arteries
3.4
6.1
21
63
U07.2
ICD-10 Finland
COVID-19, virus not identified
0.3
6.1
12
443
R47.0
ICD-10 Finland
Dysphasia and aphasia
6.2
6.0
15
25
SFA10
NOMESCO Finland
One-surface restoration
0.6
6.0
139
1952
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
146
26
79.10
267.64
1.7
2.8
—
—
—
0
0
211
0
+∞
240.83
1.0
0.0
—
—
—
0
0
220
425
8.49
120.98
4.9
7.9
4.89
5.21
kpa
5.33
215
409
220
425
8.49
120.98
4.9
7.9
17.89
11.76
kpa
24.90
215
411
220
428
8.43
120.10
4.9
7.9
1.04
1.57
mmol/l
1.76
171
341
254
592
7.73
116.04
1.8
1.8
26.46
29.57
s
12.81
245
572
100
0
+∞
108.39
1.1
0.0
—
—
—
0
0
242
798
4.96
68.72
1.9
2.1
—
—
—
0
0
325
1618
3.91
47.13
5.9
5.2
1.19
1.21
mmol/l
6.45
319
1448
321
1590
3.88
46.80
2.4
2.3
—
—
—
0
0
367
2000
4.19
46.08
18.1
6.6
4.89
4.30
e9/l
4.62
314
1753
279
1273
3.72
45.89
2.8
2.2
138.60
232.29
u/l
2.39
274
1182
45
38
12.92
45.15
1.6
1.2
—
—
—
0
0
335
1786
3.69
41.87
6.7
5.6
1.20
1.21
mmol/l
3.01
308
1553
319
1666
3.55
40.84
10.1
5.5
1.27
3.05
%
44.14
313
1546
293
4108
0.30
35.99
3.1
4.7
4.85
4.63
mmol/l
2.74
263
3792
325
1826
3.25
34.68
10.4
5.5
1.33
1.86
e9/l
26.40
277
1616
306
4179
0.30
34.61
3.3
5.3
2.98
2.74
mmol/l
3.47
273
3853
328
1864
3.23
34.09
11.0
5.6
0.09
0.20
e9/l
46.86
272
1652
293
4076
0.32
33.38
3.1
4.7
1.44
1.44
mmol/l
0.00
266
3751
231
1141
2.91
29.77
9.9
2.0
2.36
2.35
mmol/l
0.26
220
950
276
3894
0.35
29.11
3.9
6.0
39.80
40.23
mmol/mol
0.32
256
3612
51
88
6.34
28.96
1.7
1.2
46.78
5.41
e6/l
0.86
37
73
51
88
6.34
28.96
1.8
1.3
4884.61
2056.29
e6/l
0.35
38
75
54
99
6.00
28.85
1.5
1.2
862.98
455.81
mg/l
1.87
54
93
297
4032
0.35
28.05
4.0
4.7
6.09
6.02
mmol/l
0.21
262
3676
290
3942
0.37
25.53
3.0
4.2
1.30
1.33
mmol/l
0.39
264
3606
296
1806
2.58
23.24
7.6
15.6
1.10
1.31
inr
4.85
83
508
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
49
108
4.92
21.27
2.8
2.6
0.37
0.36
u/ml
0.15
36
62
32
18
18.90
21.15
1.6
1.1
—
—
—
0
0
86
302
3.23
19.46
2.0
6.6
6.80
9.82
mmol/l
4.84
80
285
30
18
17.65
19.41
1.5
1.1
—
—
—
0
0
129
580
2.65
18.52
1.8
1.8
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
28
16
18.45
18.45
1.5
1.2
—
—
—
0
0
249
1520
2.28
17.93
5.3
3.8
33.99
35.95
g/l
6.55
241
1398
25
12
21.85
17.46
1.4
2.0
—
—
—
0
0
24
36
6.95
15.43
1.3
1.0
—
—
—
0
0
27
46
6.15
15.41
1.3
1.1
—
—
—
0
0
26
44
6.18
14.93
1.3
1.1
—
—
—
0
0
93
415
2.53
13.21
1.6
1.7
—
—
—
0
0
91
410
2.49
12.64
1.5
1.8
—
—
—
0
0
78
327
2.64
12.57
1.7
1.7
285.26
360.47
nmol/l
2.68
70
300
50
165
3.26
12.38
2.0
2.4
150.51
328.64
ug/l
2.10
50
152
26
53
5.12
12.29
2.2
5.0
128.17
142.14
iu/ml
—
6
7
164
972
2.03
11.54
2.2
2.9
0.51
0.42
e6/l
0.24
121
727
175
1065
1.99
11.41
2.4
3.0
31.80
95.28
e6/l
0.52
129
816
108
567
2.16
10.38
1.9
2.8
2.48
1.57
e6/l
0.68
57
309
20
22
9.42
10.10
1.1
1.3
—
—
—
0
0
136
787
2.00
10.04
3.1
3.8
51.04
521.69
ng/l
3.85
109
627
397
4454
0.46
10.02
39.6
17.7
7.55
6.66
e9/l
11.29
379
4306
397
4454
0.46
10.02
39.6
17.7
4.38
4.57
e12/l
11.42
379
4303
55
217
2.73
9.93
1.4
1.6
—
—
—
0
0
397
4450
0.46
9.81
39.7
17.7
226.19
245.09
e9/l
8.22
380
4310
397
4449
0.46
9.76
39.8
17.7
39.99
40.93
%
3.49
367
4120
119
667
2.03
9.55
3.9
2.1
2.45
2.44
mmol/l
0.82
109
565
296
3619
0.55
9.24
3.8
4.4
1.75
2.29
mu/l
0.95
268
3284
12
5
24.52
8.94
1.2
1.8
—
—
—
0
0
54
227
2.55
8.59
1.4
1.4
—
—
—
0
0
78
1395
0.48
8.38
3.0
3.7
10.28
7.23
mg/mmol
0.27
40
892
108
613
1.97
8.26
1.9
2.6
1.68
0.99
e6/l
0.50
56
352
225
2925
0.58
8.16
3.5
3.6
14.71
14.88
pmol/l
0.42
206
2631
89
1506
0.50
8.03
2.2
2.6
229.27
135.17
ug/l
1.51
77
1377
78
1375
0.49
7.94
2.5
3.0
8.99
7.95
mmol/l
0.70
64
1150
20
640
0.28
7.93
1.1
1.3
0.94
9.96
u/ml
—
8
247
37
134
2.90
7.83
1.9
1.5
—
—
—
0
0
187
1296
1.71
7.34
2.4
2.9
—
—
—
0
0
96
1536
0.54
7.01
1.6
2.2
72.07
77.46
nmol/l
1.11
89
1354
13
14
9.50
6.82
1.5
1.1
—
—
—
0
0
71
1227
0.51
6.56
2.0
2.9
505.75
1295.71
ng/l
6.88
62
1040
13
16
8.31
6.37
1.2
1.1
—
—
—
0
0
9
5
18.29
6.28
1.1
1.4
—
—
—
0
0
11
11
10.19
6.06
1.2
1.2
—
—
—
0
0
60
1071
0.50
6.05
2.0
2.3
8105.31
7524.72
umol/l
0.03
51
927
17
34
5.14
5.92
1.2
1.4
—
—
—
0
0
50
942
0.48
5.90
1.4
1.5
17.82
21.03
nmol/l
1.32
45
804
121
1750
0.59
5.84
3.1
3.6
2.14
1.86
ug/l
0.41
102
1570
168
2238
0.62
5.71
2.7
2.6
—
—
—
0
0
235
2905
0.64
5.70
2.6
4.0
11.88
11.49
mm/h
0.14
212
2653
10
10
10.18
5.55
1.0
1.2
—
—
—
0
0
21
67
3.23
5.53
1.4
1.4
—
—
—
0
0
21
67
3.23
5.53
1.4
1.4
—
—
—
0
0
92
1412
0.57
5.50
3.0
3.5
22.09
23.75
%
0.68
42
614
114
1654
0.60
5.48
1.7
2.0
91.89
95.70
pmol/l
0.46
55
841
10
11
9.25
5.31
1.0
1.2
—
—
—
0
0
14
26
5.51
5.26
1.0
1.0
1.11
1.04
u/l
—
8
14
48
875
0.50
5.06
3.1
3.6
1.02
1.02
kg/l
0.02
13
121
98
1451
0.60
5.00
3.2
3.5
—
—
—
0
0
40
194
2.15
4.64
2.3
1.4
3.45
2.55
ug/l
0.56
23
150
41
766
0.49
4.62
1.1
1.2
0.47
1.94
u/ml
1.87
11
219
32
145
2.29
4.38
2.2
1.6
—
—
—
0
0
13
29
4.57
4.27
1.8
1.9
—
—
—
0
0
66
397
1.76
4.12
1.9
2.1
4.73
7.73
umol/l
2.64
61
341
8
10
8.11
4.07
2.4
1.9
—
—
—
0
0
13
32
4.14
3.93
1.2
1.4
—
—
—
0
0
8
11
7.37
3.87
1.3
1.2
—
—
—
0
0
8
11
7.37
3.87
1.3
1.2
—
—
—
0
0
64
997
0.59
3.84
3.2
3.6
0.00
0.01
estimate
0.50
25
284
52
856
0.56
3.84
1.3
1.7
484.05
22111711.31
pmol/l
0.69
42
701
8
12
6.75
3.68
1.3
1.2
—
—
—
0
0
8
12
6.75
3.68
1.3
1.1
—
—
—
0
0
11
27
4.14
3.41
1.0
1.0
—
—
—
0
0
6
7
8.66
3.27
1.2
1.3
—
—
—
0
0
67
990
0.63
3.18
2.2
2.5
0.60
0.71
ug/l
1.25
42
635
6
8
7.57
3.06
1.5
1.4
—
—
—
0
0
5
5
10.08
2.98
1.2
1.0
—
—
—
0
0
5
5
10.08
2.98
2.0
1.0
—
—
—
0
0
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
5
5
10.08
2.98
1.0
6.4
202.80
87.40
%
—
5
5
8
17
4.76
2.93
2.3
1.8
452.63
738.47
e6/l
—
8
17
17
70
2.48
2.91
1.2
1.8
—
—
—
0
0
19
83
2.34
2.87
2.2
1.7
15.29
74.17
u/ml
0.48
14
64
346
3787
0.72
2.86
26.5
10.9
88.28
79.40
ml/min/173m2
17.50
305
3047
7
14
5.05
2.73
1.3
1.1
—
—
—
0
0
7
14
5.05
2.73
1.0
1.1
—
—
—
0
0
194
1595
1.35
2.71
3.5
3.6
17.38
62.12
ng/l
1.44
165
1154
151
1850
0.74
2.53
2.7
3.4
0.00
0.01
estimate
0.74
29
314
11
37
3.02
2.50
1.1
1.1
—
—
—
0
0
21
105
2.04
2.34
1.3
1.5
—
—
—
0
0
153
1848
0.75
2.26
3.9
4.7
0.00
0.00
estimate
-0.00
28
292
12
261
0.45
2.11
1.6
1.9
—
—
—
0
0
53
361
1.52
2.09
3.7
3.0
—
—
—
0
0
5
10
5.04
2.07
1.0
3.4
126.00
90.30
%
—
5
10
36
551
0.63
1.98
7.8
6.7
—
—
—
0
0
158
1872
0.77
1.95
2.8
3.5
0.00
0.01
estimate
0.50
26
285
68
912
0.71
1.94
1.5
2.1
2.80
3.01
mg/l
0.27
54
758
31
189
1.68
1.92
1.9
2.2
0.64
0.63
%
0.07
31
189
0
50
0.00
1.89
0.0
1.4
—
64.06
—
0
34
94
1191
0.74
1.88
2.2
2.3
52.50
61.80
u/l
1.37
88
1095
13
59
2.24
1.85
1.2
1.3
—
—
—
0
0
11
234
0.46
1.84
1.5
1.8
—
—
—
0
0
31
196
1.62
1.70
1.9
2.3
1.25
1.33
%
0.19
31
196
36
531
0.65
1.69
1.1
1.4
—
—
—
0
0
32
480
0.64
1.63
1.4
1.8
1.34
1.55
%
1.24
24
417
16
84
1.93
1.61
1.1
1.1
—
—
—
0
0
143
1205
1.26
1.53
6.2
2.8
28.01
33.18
u/l
2.06
138
1140
23
366
0.61
1.52
1.6
1.9
—
—
—
0
0
15
79
1.93
1.51
1.3
1.4
—
—
—
0
0
9
37
2.46
1.48
1.3
1.4
0.63
1.40
promille
—
9
32
15
80
1.90
1.46
1.2
1.3
—
—
—
0
0
11
53
2.10
1.39
1.2
1.4
—
—
—
0
0
11
53
2.10
1.39
1.2
1.4
—
—
—
0
0
14
75
1.89
1.35
1.2
1.5
—
—
—
0
0
0
38
0.00
1.35
0.0
1.4
—
155.67
—
0
38
20
121
1.68
1.32
1.6
3.5
—
—
—
0
0
24
154
1.59
1.28
4.1
3.9
1.56
1.42
mmol/l
0.36
24
149
33
464
0.69
1.25
1.5
2.3
28.31
24.27
%
0.73
26
397
9
45
2.02
1.24
1.4
1.3
—
—
—
0
0
5
21
2.39
1.09
1.2
1.2
—
—
—
0
0
8
41
1.97
1.09
1.0
1.4
—
—
—
0
0
8
41
1.97
1.09
1.0
1.4
—
—
—
0
0
59
736
0.77
1.05
1.5
1.7
901.25
1199.19
nmol/l
2.92
44
553
33
239
1.41
1.03
1.6
3.4
1.75
2.17
mmol/l
0.34
28
177
40
525
0.74
1.03
3.3
4.7
29.53
31.69
%
0.88
30
350
7
34
2.07
1.03
1.1
1.6
—
—
—
0
0
5
106
0.47
1.02
1.2
1.2
—
2.85
—
0
6
34
249
1.39
1.01
1.3
1.4
—
50.82
—
0
17
9
159
0.56
1.00
1.0
1.0
—
—
—
0
0
0
29
0.00
0.98
0.0
1.1
—
—
—
0
0
0
30
0.00
0.97
0.0
1.7
—
25.33
—
0
6
9
51
1.78
0.95
1.4
1.3
—
—
—
0
0
37
280
1.35
0.91
2.3
2.6
—
21.44
—
0
15
7
129
0.54
0.89
1.7
1.4
—
—
—
0
0
27
198
1.38
0.82
2.6
2.8
25.87
25.45
mmol/l
0.35
27
192
0
24
0.00
0.79
0.0
1.1
—
244.48
—
0
24
0
26
0.00
0.78
0.0
9.6
—
37.08
—
0
12
5
100
0.49
0.78
1.2
1.2
—
4.65
—
0
17
10
59
1.71
0.76
1.1
1.1
—
—
—
0
0
9
56
1.62
0.72
3.0
3.2
68.00
59.05
%
—
9
56
11
68
1.63
0.72
1.2
1.4
—
—
—
0
0
5
95
0.52
0.67
1.0
1.1
—
13.64
—
0
8
15
213
0.70
0.66
1.2
1.2
122.30
101.66
iu/ml
—
5
91
0
22
0.00
0.59
0.0
1.3
—
—
—
0
0
8
55
1.46
0.56
4.3
2.0
102.50
105.62
mmol/l
—
8
55
32
393
0.80
0.55
1.2
1.4
—
—
—
0
0
6
39
1.54
0.53
1.3
1.1
—
—
—
0
0
7
50
1.41
0.45
1.3
1.4
—
—
—
0
0
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
7
102
0.68
0.40
1.9
1.5
—
—
—
0
0
8
111
0.72
0.37
1.5
1.1
—
—
—
0
0
5
37
1.35
0.37
1.4
1.7
—
—
—
0
0
12
90
1.34
0.36
1.2
1.3
—
—
—
0
0
37
320
1.17
0.36
1.8
2.1
32.59
31.93
u/l
0.06
32
266
6
46
1.31
0.33
1.7
1.3
—
—
—
0
0
270
2611
1.07
0.32
4.1
3.0
73.93
49.39
u/l
1.14
261
2427
7
54
1.30
0.30
1.6
1.5
—
—
—
0
0
19
157
1.22
0.30
2.0
3.8
25.02
25.04
mmol/l
0.01
19
147
7
57
1.23
0.29
1.6
1.4
—
—
—
0
0
14
173
0.80
0.29
1.5
1.3
—
—
—
0
0
8
62
1.30
0.28
1.5
1.3
16.45
24.51
iu/l
—
8
53
6
83
0.72
0.24
1.2
1.5
—
—
—
0
0
45
409
1.11
0.23
1.4
2.5
2.43
7.95
ug/l
7.32
37
360
25
218
1.15
0.23
1.1
1.5
—
—
—
0
0
5
41
1.22
0.22
1.8
2.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
9.37
—
0
11
5
43
1.16
0.21
1.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
3.5
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
3.5
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
9
111
0.81
0.20
1.4
1.1
—
—
—
0
0
22
194
1.14
0.19
2.9
2.5
1.05
0.21
e6/l
0.52
22
187
8
68
1.18
0.16
1.5
1.1
—
—
—
0
0
6
77
0.78
0.15
1.0
1.2
—
—
—
0
0
12
140
0.85
0.15
1.2
1.4
—
—
—
0
0
6
54
1.11
0.09
1.5
1.5
1.10
0.70
nmol/l
—
6
49
6
55
1.09
0.09
1.0
1.1
—
—
—
0
0
9
102
0.88
0.06
1.2
1.3
—
1.07
—
0
14
10
92
1.09
0.03
1.0
1.4
—
—
—
0
0
31
313
0.99
0.00
5.9
2.1
73.50
64.20
ml/min/173m2
0.79
14
123
82
824
0.99
0.00
1.6
1.6
3.18
1.09
mg/l
1.54
71
631
28
278
1.01
0.00
1.6
2.1
0.28
0.21
g/l
3.51
28
249
393
3933
1.00
0.00
27.5
12.0
17.02
23.22
mg/l
7.68
379
2975
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
6.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
2.76
—
0
8
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
53
0.94
-0.00
1.0
1.2
7.00
7.55
mmol/l
—
5
43
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.0
—
0.40
—
0
5
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
107.75
—
0
8
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: C3_GBM – Brain glioblastoma
GWS hits: 3
This endpoint is excluded from FinRegistry analyses (omitted endpoint).