Brain glioblastoma and astrocytoma

C3_GBM_ASTROCYTOMA

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

  • HLP_C3_GBM
  • or HLP_C3_ASTROCYTOMA
654

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 C71
  • Cause of death: ICD-9 191
  • Cause of death: ICD-8 191
  • Cancer registry: Topography ICD-O-3 C71
  • Cancer registry: Morphology ICD-O-3 9400|9440
  • Cancer registry: Behaviour codes 3

2 out of 7 registries used, show all original rules.

654

4. Check minimum number of events

None

654

5. Include endpoints

654

6. Filter based on genotype QC (FinnGen only)

618

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy
C
First used in FinnGen datafreeze
DF9

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 618 260 358
Unadjusted period prevalence (%) 0.13 0.09 0.16
Median age at first event (years) 62.05 61.49 62.46

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
654
Matched controls
6540
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
WF002
NOMESCO Finland
Radical radiotherapy
1262.1
320.4
287
*
ZXC95
NOMESCO Finland
Use of surgical navigator
99.5
307.7
170
23
A03FA01
ATC
metoclopramide; systemic, rectal
27.4
307.7
423
409
130
Kela drug reimbursment
Malignant tumour
+∞
307.7
520
*
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
84.0
307.7
272
55
Z51.5
ICD-10 Finland
Palliative care
58.2
307.7
278
82
A04AA01
ATC
ondansetron; systemic, rectal
53.2
307.7
206
56
L01AX03
ATC
temozolomide; systemic
+∞
307.7
467
*
H02AB02
ATC
dexamethasone; systemic
1235.5
307.7
559
31
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
2650.5
307.7
493
7
N03AX14
ATC
levetiracetam; systemic
135.8
307.7
367
61
A04AA02
ATC
granisetron; systemic, transdermal
4616.7
307.7
288
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
45.2
307.7
397
216
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
51.8
307.7
360
151
XX3DW
NOMESCO Finland
Time consuming IT work
26.2
293.3
227
130
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
35.8
267.1
177
67
D43.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, supratentorial
641.2
258.8
240
6
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
39.5
243.7
155
51
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
211.2
191
*
C71.23
ICD-10 Finland
Malignant tumor of temporal lobe grade IV glioma
+∞
211.2
191
*
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
32.7
205.5
138
53
C71.2
ICD-10 Finland
Malignant neoplasm: Temporal lobe
+∞
189.0
172
*
AAG50
NOMESCO Finland
Stereotactic intracranial radiotherapy
1178.8
187.2
174
*
9440/3-C71.9
ICD-O-3
Glioblastoma, NOS, of brain, NOS
+∞
185.5
169
*
N03AX18
ATC
lacosamide; systemic
69.3
181.8
100
17
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
+∞
176.2
161
*
C71.13
ICD-10 Finland
Malignant tumor of frontal lobe grade IV glioma
+∞
172.8
158
*
C71.10
ICD-10 Finland
Malignant tumor in frontal lobe without histology
+∞
170.5
156
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
168.2
154
*
N03AF02
ATC
oxcarbazepine; oral
19.5
162.1
135
86
C71.1
ICD-10 Finland
Malignant neoplasm: Frontal lobe
+∞
161.3
148
*
C71.20
ICD-10 Finland
Malignant tumor in temporal lobe without histology
+∞
160.2
147
*
AA1AD
NOMESCO Finland
CT of head and brain
7.4
146.3
398
1137
C71.90
ICD-10 Finland
Malignant tumor in unspecified localization in the brain without histology
+∞
143.1
132
*
WX882
NOMESCO Finland
High dependency care
25.1
133.4
97
45
9440/3-C71.2
ICD-O-3
Glioblastoma, NOS, of temporal lobe
+∞
130.7
121
*
R56.8
ICD-10 Finland
Other and unspecified convulsions
11.1
121.9
145
164
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
278.4
115.9
115
5
AAG00
NOMESCO Finland
Stereotactic intracranial biopsy
+∞
112.9
105
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
6.4
110.5
248
568
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
411.6
105.5
103
*
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
10.7
105.0
126
143
9440/3-C71.1
ICD-O-3
Glioblastoma, NOS, of frontal lobe
+∞
102.9
96
*
YX8VG
NOMESCO Finland
Stereotactic MRI exmaination with high intensity magnet for dose design of radiotherapy
1080.2
97.6
93
*
N02AA05
ATC
oxycodone; systemic
6.3
96.7
207
448
C71.33
ICD-10 Finland
Malignant tumor of parietal lobe grade IV glioma
+∞
95.2
89
*
N05CD08
ATC
midazolam; nasal, systemic
16.9
94.6
82
55
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
6.7
90.8
172
329
C71.11
ICD-10 Finland
Malignant tumor of frontal lobe grade II glioma
+∞
87.5
82
*
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
33.9
86.7
56
18
YX8BD
NOMESCO Finland
Stereotactic extensive CT examination for dose design of radiotherapy
477.2
86.2
84
*
ZX095
NOMESCO Finland
Combined chemoradiotherapy
+∞
84.2
79
*
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
39.4
82.5
51
14
G40.9
ICD-10 Finland
Epilepsy, unspecified
10.3
80.4
96
107
AA1BD
NOMESCO Finland
Extensive CT of head and brain
18.2
79.9
66
40
C71.30
ICD-10 Finland
Malignant tumor in parietal lobe without histology
+∞
79.9
75
*
WZC00
NOMESCO Finland
Treatment plan or consultation
4.5
78.4
321
1161
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
425.2
77.5
76
*
C71.3
ICD-10 Finland
Malignant neoplasm: Parietal lobe
+∞
74.4
70
*
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
40.2
73.2
45
12
WZC30
NOMESCO Finland
Teaching
5.4
72.3
173
406
ZX050
NOMESCO Finland
Stereotactic radiotherapy
+∞
72.2
68
*
XA800
NOMESCO Finland
Neuropsychological investigation
9.0
71.6
95
121
ZXC40
NOMESCO Finland
Use of ultrasound
105.7
69.5
75
8
D43.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Central nervous system, unspecified
368.4
67.9
67
*
N74
ICPC
Malignant neoplasm nervous system
681.4
64.0
62
*
C71.21
ICD-10 Finland
Malignant tumor of temporal lobe grade II glioma
+∞
63.6
60
*
WX402
NOMESCO Finland
General anaesthesia
4.4
63.2
213
652
C71.83
ICD-10 Finland
Overall malignant tumor of the brain grade IV glioma
+∞
62.5
59
*
C71.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of brain
+∞
60.4
57
*
9400/3-C71.9
ICD-O-3
Astrocytoma, NOS, of brain, NOS
+∞
60.4
57
*
D43.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, unspecified
608.9
57.6
56
*
N03AB02
ATC
phenytoin; systemic
17.2
56.9
48
30
ZXM40
NOMESCO Finland
Use of fluorescent substance
597.0
56.5
55
*
9400/3-C71.1
ICD-O-3
Astrocytoma, NOS, of frontal lobe
+∞
56.1
53
*
YA1VG
NOMESCO Finland
MRI examination of head and neck with high intesity magnet for dose design of radiotherapy
203.7
54.9
56
*
C71.99
ICD-10 Finland
Malignant tumor in unspecified localization in the brain other or unspecified histology
+∞
53.9
51
*
9440/3-C71.3
ICD-O-3
Glioblastoma, NOS, of parietal lobe
+∞
52.8
50
*
H53.4
ICD-10 Finland
Visual field defects
13.1
52.8
52
43
A02BC02
ATC
pantoprazole; systemic
4.3
50.1
532
3308
R90.8
ICD-10 Finland
Other abnormal findings on diagnostic imaging of central nervous system
18.5
49.3
40
23
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
21.7
49.0
37
18
ZX070
NOMESCO Finland
Intensity modified radiotherapy
502.8
48.0
47
*
ZXE20
NOMESCO Finland
More than three and less than five hours
4.3
47.6
145
404
JN4BD
NOMESCO Finland
Extensive body CT
6.8
46.6
78
128
C71.29
ICD-10 Finland
Malignant tumor in temporal lobe other or unspecified histology
+∞
46.4
44
*
A28
ICPC
Limited function/disability NOS
3.8
46.3
176
574
R4120
NOMESCO Finland
Occupational therapy
5.7
45.7
93
185
WX872
NOMESCO Finland
Intensive care
5.7
43.5
87
170
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
17.3
43.0
36
22
A79
ICPC
Malignancy NOS
+∞
42.1
40
*
ZX090
NOMESCO Finland
Other technic of radiotherapy
114.9
40.2
43
*
C71.12
ICD-10 Finland
Malignant tumor of frontal lobe grade III glioma
+∞
40.0
38
*
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
37.9
36
*
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
9.0
36.9
47
56
C79.30
ICD-10 Finland
Secondary malignant tumor of the cerebrum
+∞
36.8
35
*
WX408
NOMESCO Finland
General anesthesy, balanced
3.1
36.2
207
856
C71.22
ICD-10 Finland
Malignant tumor of temporal lobe grade III glioma
+∞
35.8
34
*
A98
ICPC
Health maint/preventive medicine
0.3
35.6
478
5872
C71.93
ICD-10 Finland
Malignant tumor in an unspecified localization in the brain grade IV glioma
+∞
34.7
33
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
3.2
33.4
163
612
C71.19
ICD-10 Finland
Malignant tumor of frontal lobe other or unspecified histology
+∞
32.6
31
*
AAA10
NOMESCO Finland
Biopsy through craniotomy
+∞
32.6
31
*
C71.80
ICD-10 Finland
Overall malignant tumor of the brain without histology
+∞
32.6
31
*
JN4AD
NOMESCO Finland
Body CT examination
5.3
31.6
68
141
C71.43
ICD-10 Finland
Malignant tumor of the occipital lobe grade IV glioma
+∞
31.5
30
*
R4110
NOMESCO Finland
Physiotherapy
2.8
30.6
218
1003
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.1
30.0
158
616
G40.10
ICD-10 Finland
Simple partial seizures
42.3
29.3
36
9
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
108.3
28.9
31
*
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
8.3
28.4
38
48
C71.00
ICD-10 Finland
Malignant tumor of the cerebrum except lobes and ventricles without histology
+∞
28.3
27
*
C71.40
ICD-10 Finland
Malignant tumor of the occipital lobe without histology
+∞
28.3
27
*
N05CF01
ATC
zopiclone; oral
2.5
28.3
261
1353
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
9.2
28.3
35
40
WC105
NOMESCO Finland
Simple cytostatic therapy of local tumor recidive
293.5
28.0
28
*
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
30.1
27.9
37
13
9400/3-C71.2
ICD-O-3
Astrocytoma, NOS, of temporal lobe
+∞
27.3
26
*
C71.9
ICD-10 Finland
Malignant neoplasm: Brain, unspecified
+∞
27.3
26
*
WF029
NOMESCO Finland
Radiotherapy of local residive tumor
+∞
27.3
26
*
N76
ICPC
Neoplasm nervous system unspecified
+∞
27.3
26
*
B01AB10
ATC
tinzaparin; parenteral
4.0
26.5
81
222
N05BA09
ATC
clobazam; oral
25.3
25.9
36
15
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
270.8
25.9
26
*
WX704
NOMESCO Finland
Intubation
4.1
25.5
75
200
N03AG01
ATC
valproic acid; systemic, rectal
4.0
25.4
77
210
R4130
NOMESCO Finland
Speech therapy
7.3
25.3
38
55
D43.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, infratentorial
135.2
24.8
26
*
TPH04
NOMESCO Finland
Cathetrisation of vein
2.7
24.2
170
764
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
+∞
24.1
23
*
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
7.7
23.1
33
45
R90.0
ICD-10 Finland
Intracranial space-occupying lesion
+∞
23.1
22
*
H02AB04
ATC
methylprednisolone; systemic
2.9
22.6
124
489
ZXE30
NOMESCO Finland
More than five and less than seven hours
5.4
22.4
46
91
C71.01
ICD-10 Finland
Malignant tumor of cerebellum except lobes and ventricles grade II glioma
+∞
22.0
21
*
9440/3-C71.0
ICD-O-3
Glioblastoma, NOS, of cerebrum
+∞
22.0
21
*
H02AB09
ATC
hydrocortisone; systemic
7.4
21.8
32
45
C71.03
ICD-10 Finland
Malignant tumor of cerebellum except lobes and ventricles grade IV glioma
+∞
20.9
20
*
C71.31
ICD-10 Finland
Malignant tumor of the parietal lobe grand II glioma
+∞
20.9
20
*
9440/3-C71.8
ICD-O-3
Glioblastoma, NOS, of overlapping lesion of brain
+∞
20.9
20
*
C71.4
ICD-10 Finland
Malignant neoplasm: Occipital lobe
+∞
19.9
19
*
G41.9
ICD-10 Finland
Status epilepticus, unspecified
27.0
19.3
26
10
XX9BW
NOMESCO Finland
Submitting image material and/or investigation material to authority or other institution
16.5
19.0
30
19
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
18.8
18
*
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
14.7
18.7
31
22
C61
ICD-10 Finland
Malignant neoplasm of prostate
195.4
18.6
19
*
G40.19
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
18.2
18.4
28
16
N05BA04
ATC
oxazepam; oral
2.2
17.4
191
1031
115
Kela drug reimbursment
Breast cancer
+∞
16.7
16
*
N03AF01
ATC
carbamazepine; oral, rectal
3.6
16.3
56
166
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
0.2
16.1
23
1025
N03AX23
ATC
brivaracetam; systemic
27.0
15.7
21
8
WF049
NOMESCO Finland
Radiotherapy of metastasis
87.2
15.6
17
*
TPH07
NOMESCO Finland
Cathetrisation of artery
2.9
15.4
80
304
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.9
15.2
76
283
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
3.7
15.0
49
140
ZXD10
NOMESCO Finland
Scheduled procedure
2.0
14.9
248
1546
9440/3-C71.4
ICD-O-3
Glioblastoma, NOS, of occipital lobe
+∞
14.6
14
*
C71.0
ICD-10 Finland
Malignant neoplasm: Cerebrum, except lobes and ventricles
+∞
14.6
14
*
PJA12
NOMESCO Finland
Sentinel node biopsy
153.3
14.5
15
*
G40.11
ICD-10 Finland
Simple partial epileptic seizure that develops into a complex partial seizure
27.9
14.3
19
7
R4150
NOMESCO Finland
Neuropsychological rehabilitation
11.2
14.1
26
24
WX110
NOMESCO Finland
Infiltration anesthesia
2.0
14.1
460
3561
YX8AD
NOMESCO Finland
Stereotactic CT examination for dose design of radiotherapy
76.8
13.6
15
*
C71.39
ICD-10 Finland
Malignant tumor of parietal lobe other or unspecified histology
+∞
13.6
13
*
AWB00
NOMESCO Finland
Reoperation for superficial infection in surgery of the nervous system
+∞
13.6
13
*
C71.32
ICD-10 Finland
Malignant tumor of parietal lobe grade III glioma
+∞
13.6
13
*
ZSA00
NOMESCO Finland
Procedure related to previous procedure classified in chapter A
26.4
13.4
18
7
C10AA07
ATC
rosuvastatin; oral
0.4
13.3
66
1497
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
11.9
12.9
23
20
N05BA06
ATC
lorazepam; systemic, sublingual
3.4
12.7
48
151
R47.0
ICD-10 Finland
Dysphasia and aphasia
9.6
12.6
25
27
WX725
NOMESCO Finland
Noninvasive ventilation
3.4
12.6
46
142
YX9BD
NOMESCO Finland
Other extensive CT eamination for dose design of radiotherapy
+∞
12.5
12
*
C71
ICD-10 Finland
Malignant neoplasm of brain
+∞
12.5
12
*
G93.6
ICD-10 Finland
Cerebral oedema
+∞
12.5
12
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
12.5
12
*
XF400
NOMESCO Finland
ECG with 12 standard connections
2.2
12.1
116
585
Z73.3
ICD-10 Finland
Stress, not elsewhere classified
13.7
12.0
20
15
G41.2
ICD-10 Finland
Complex partial status epilepticus
66.2
11.6
13
*
WW200, ,
SPAT
0.3
11.6
35
1020
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.5
11.6
80
350
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
11.5
11
*
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
0.5
11.3
130
2168
GD1AA, ,
SPAT
0.1
11.0
6
425
SPAT1245
SPAT
Provision of support and information to patient’s family members
3.8
10.9
34
94
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
0.3
10.8
38
1029
183
Kela drug reimbursment
Lamotrigin and topiramate
9.8
10.8
21
22
TKC20
NOMESCO Finland
Catheterisation of bladder
2.8
10.8
54
201
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.1
10.7
111
575
D69.5
ICD-10 Finland
Secondary thrombocytopenia
61.0
10.7
12
*
M25.5
ICD-10 Finland
Pain in joint
0.4
10.5
68
1402
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
111.7
10.4
11
*
ZX080
NOMESCO Finland
Image guided radiotherapy
+∞
10.4
10
*
Z51.0
ICD-10 Finland
Radiotherapy session
+∞
10.4
10
*
C71.81
ICD-10 Finland
Overall malignant tumor of the brain grade II glioma
+∞
10.4
10
*
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
0.4
10.2
47
1122
I61.9
ICD-10 Finland
Intracerebral haemorrhage, unspecified
5.4
10.2
20
38
WX892
NOMESCO Finland
Monitored bed care
2.6
10.1
62
256
M79.6
ICD-10 Finland
Pain in limb
0.5
10.1
110
1884
WPA10
NOMESCO Finland
Proactive palliative care treatment plan
55.8
9.7
11
*
C10AX09
ATC
ezetimibe; oral
0.2
9.7
18
694
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
101.5
9.4
10
*
G91.1
ICD-10 Finland
Obstructive hydrocephalus
17.8
9.4
14
8
WPA15
NOMESCO Finland
Palliative care consultation with the patient and loved ones
30.5
9.4
12
*
AA5BD
NOMESCO Finland
CT of cerebral ischaemia
4.1
9.4
26
66
OAA41
NOMESCO Finland
Health check based on individual needs
+∞
9.4
9
*
9400/3-C71.0
ICD-O-3
Astrocytoma, NOS, of cerebrum
+∞
9.4
9
*
SAA01
NOMESCO Finland
Simple examination of mouth
0.6
9.2
291
3737
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
9.1
212
1424
G40.89
ICD-10 Finland
Other epilepsy
18.9
9.0
13
7
L02BA01
ATC
tamoxifen; oral
24.4
8.9
12
5
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.6
8.9
53
216
A10BK03
ATC
empagliflozin; oral
0.2
8.7
7
383
SPAT1109
SPAT
Analgesia with portable analgesic pump
50.7
8.7
10
*
HAB40
NOMESCO Finland
Wedge excision of mammary gland
20.3
8.5
12
6
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
2.6
8.4
49
197
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
6.8
8.4
20
30
XA400
NOMESCO Finland
EEG
13.0
8.4
14
11
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
8.3
8
*
C71.02
ICD-10 Finland
Malignant tumor of the cerebrum except lobes and ventricles grade III glioma
+∞
8.3
8
*
WB401
NOMESCO Finland
Simple antibody therapy of primary tumour
+∞
8.3
8
*
A04AA55
ATC
palonosetron, combinations; systemic
+∞
8.3
8
*
C50.40
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, no histological veryfication
+∞
8.3
8
*
AA5FG
NOMESCO Finland
Functional MRI examination of brain with high intensity magnet
+∞
8.3
8
*
C50.99
ICD-10 Finland
Breast, unspecified
+∞
8.3
8
*
C71.50
ICD-10 Finland
Malignant tumor of cerebral ventricle without histology
+∞
8.3
8
*
C71.91
ICD-10 Finland
Malignant tumor in unspecified location in the brain grade II glioma
+∞
8.3
8
*
JN4CD
NOMESCO Finland
Very extensive body CT
7.2
8.3
19
27
SAA02
NOMESCO Finland
Basic examination of mouth
0.6
8.3
255
3338
C07AB07
ATC
bisoprolol; oral
0.6
8.2
160
2346
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
0.5
8.1
67
1280
Z02.4
ICD-10 Finland
Examination for driving licence
0.5
8.1
63
1230
Z76.0
ICD-10 Finland
Issue of repeat prescription
0.4
8.0
40
930
206
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
0.3
7.8
29
773
A10AB05
ATC
insulin aspart; parenteral
2.3
7.8
57
256
I26.0
ICD-10 Finland
Pulmonary embolism with mention of acute cor pulmonale
4.4
7.7
19
44
I25.1
ICD-10 Finland
Atherosclerotic heart disease
0.4
7.7
44
970
B01AB05
ATC
enoxaparin; parenteral
1.7
7.7
170
1118
L17
ICPC
Foot/toe symptom/complaint
0.5
7.7
63
1209
M54.4
ICD-10 Finland
Lumbago with sciatica
0.3
7.7
27
738
G40.21
ICD-10 Finland
Partial epileptic seizure with cloudiness and automatism
25.3
7.6
10
*
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
2.1
7.6
75
381
U07.2
ICD-10 Finland
COVID-19, virus not identified
0.3
7.5
28
744
R51.80
ICD-10 Finland
Headache
1.9
7.4
101
574
ZXH01
NOMESCO Finland
Procedure performed within operation theatre
81.0
7.4
8
*
2151
FHL
Resection, big brain
81.0
7.4
8
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
81.0
7.4
8
*
SPAT1290
SPAT
Preparation of deceased person
81.0
7.4
8
*
WZC00, ,
SPAT
0.2
7.4
7
347
SDA03
NOMESCO Finland
Periodontal treatment
0.6
7.4
113
1786
R83
ICPC
Respiratory infection other
0.4
7.3
50
1029
F80.1
ICD-10 Finland
Expressive language disorder
11.0
7.3
13
12
C71.09
ICD-10 Finland
Malignant tumor of the cerebrum except lobes and ventricles other or unspecified histology
+∞
7.3
7
*
9400/3-C71.3
ICD-O-3
Astrocytoma, NOS, of parietal lobe
+∞
7.3
7
*
OAB38
NOMESCO Finland
Psychosocial guidance and counselling
+∞
7.3
7
*
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
+∞
7.3
7
*
C71.82
ICD-10 Finland
Overall malignant tumor of the brain grade III glioma
+∞
7.3
7
*
EB1VA, ,
NOMESCO Finland
0.2
7.3
10
470
N02BF01
ATC
gabapentin; oral
0.1
7.2
*
279
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
3.1
7.1
29
96
OAB42, ,
SPAT
0.2
7.1
9
375
HA1AA
NOMESCO Finland
X-ray mammography
3.7
7.1
22
61
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
2.7
7.1
38
147
N05AD01
ATC
haloperidol; systemic
3.4
7.0
25
76
N19
ICPC
Speech disorder
6.4
7.0
17
27
C01DA14
ATC
isosorbide mononitrate; oral
0.3
6.9
19
592
R41.0
ICD-10 Finland
Disorientation, unspecified
3.2
6.9
27
87
A10BA02
ATC
metformin; oral
0.5
6.8
72
1274
L03AA02
ATC
filgrastim; parenteral
40.5
6.8
8
*
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
0.3
6.7
22
626
M75.1
ICD-10 Finland
Rotator cuff syndrome
0.5
6.7
58
1098
D33.00
ICD-10 Finland
Medial pilosytic astrocytoma of the cerebrum
22.8
6.7
9
*
N03AX22
ATC
perampanel; oral
22.8
6.7
9
*
WX002
NOMESCO Finland
Sedation and analgesia
1.8
6.6
116
714
C10AA05
ATC
atorvastatin; oral
0.6
6.5
134
1972
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
3.7
6.5
20
55
R93.0
ICD-10 Finland
Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified
70.5
6.4
7
*
XX1AD
NOMESCO Finland
Other CT-examination
70.5
6.4
7
*
H25.1
ICD-10 Finland
Senile nuclear cataract
0.5
6.4
56
1058
L03
ICPC
Low back symptom/complaint
0.5
6.3
64
1149
N03AF04
ATC
eslicarbazepine; oral
+∞
6.3
6
*
HA003
NOMESCO Finland
Radiotherapy after partial ablation of mammary gland
+∞
6.3
6
*
C50.21
ICD-10 Finland
Malignant tumor of the upper inner quadrant of the mammary gland,ductal tumor
+∞
6.3
6
*
AA5NK
NOMESCO Finland
Tractography within white matter of central nervous system
+∞
6.3
6
*
WD505
NOMESCO Finland
Simple enzyme inhibitor or similar therapy of methastized malignancy
+∞
6.3
6
*
AA003
NOMESCO Finland
Adjuvant radiotherapy of brain
+∞
6.3
6
*
C72.9
ICD-10 Finland
Malignant neoplasm: Central nervous system, unspecified
+∞
6.3
6
*
C71.89
ICD-10 Finland
Overall malignant tumor of the brain other or unspecified histology
+∞
6.3
6
*
1CD02, ,
NOMESCO Finland
+∞
6.3
6
*
THW99
NOMESCO Finland
Other minor procedure in surgery of mammary gland
26.9
6.2
8
*
L03AA13
ATC
pegfilgrastim; parenteral
26.9
6.2
8
*
M01AC06
ATC
meloxicam; systemic, rectal
0.6
6.0
109
1663
205
Kela drug reimbursment
Chronic hypertension
0.5
6.0
61
1100
SPAT1229
SPAT
Assessment of need for aid
2.3
6.0
47
217

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
388
127
73.66
307.65
1.3
1.3
—
—
—
0
0
217
224
14.00
199.10
4.4
9.0
24.42
24.83
mmol/l
1.19
217
219
302
522
9.89
186.46
5.1
7.7
0.98
1.44
mmol/l
1.83
234
421
302
523
9.87
186.12
5.1
7.7
4.91
5.18
kpa
5.15
295
503
302
523
9.87
186.12
5.1
7.7
18.35
11.61
kpa
40.06
295
505
316
740
7.33
142.01
1.8
1.8
26.70
29.55
s
8.73
305
714
421
1538
5.88
109.75
3.2
1.6
—
—
—
0
0
383
1352
5.42
102.26
2.1
2.1
—
—
—
0
0
328
1047
5.28
98.30
1.9
2.0
—
—
—
0
0
380
1582
4.35
75.86
2.6
2.2
180.49
272.66
u/l
0.82
372
1476
441
2045
4.55
75.67
5.9
5.1
1.19
1.21
mmol/l
9.21
432
1835
310
1159
4.18
70.94
3.6
3.3
96.98
88.77
%
8.89
303
1124
66
50
14.57
70.88
1.7
1.2
—
—
—
0
0
455
2254
4.35
68.80
6.7
5.6
1.20
1.21
mmol/l
4.52
416
1953
183
473
4.98
67.87
5.9
8.0
98.00
95.12
%
7.78
178
457
435
2129
4.12
65.93
2.4
2.3
—
—
—
0
0
491
2683
4.33
61.74
17.7
6.6
4.52
4.29
e9/l
1.32
419
2357
56
44
13.83
58.70
1.7
1.1
—
—
—
0
0
76
97
8.73
56.90
1.7
1.1
—
—
—
0
0
429
2232
3.68
55.86
10.7
5.8
—
—
—
0
0
416
2145
3.58
54.46
9.9
5.7
0.39
0.69
%
22.94
411
2002
419
2220
3.47
51.44
10.0
5.6
1.44
2.99
%
46.37
413
2074
431
2392
3.35
47.57
10.0
5.4
0.54
0.58
e9/l
4.14
359
2094
431
2400
3.33
47.14
10.0
5.4
0.03
0.04
e9/l
21.72
357
2106
308
1422
3.20
46.39
9.4
2.0
2.36
2.35
mmol/l
1.08
290
1193
437
2485
3.29
45.46
10.6
5.7
0.09
0.20
e9/l
55.81
362
2208
133
365
4.32
44.38
5.0
7.1
—
—
—
0
0
431
2458
3.21
44.07
10.2
5.5
1.35
1.88
e9/l
36.01
365
2186
289
1327
3.11
43.28
1.2
1.4
—
—
—
0
0
103
235
5.02
43.26
6.3
11.1
—
—
—
0
0
70
114
6.76
42.05
1.7
1.2
43.35
6.73
e6/l
1.12
51
94
70
114
6.76
42.05
1.8
1.3
3792.53
1604.08
e6/l
0.38
53
97
394
5356
0.33
38.65
3.0
4.5
4.86
4.63
mmol/l
3.64
354
4976
409
5438
0.34
36.96
3.2
5.0
3.00
2.76
mmol/l
4.74
364
5040
255
1179
2.91
36.47
3.2
3.8
—
—
—
0
0
43
47
9.72
36.02
2.0
1.2
—
—
—
0
0
394
5315
0.35
35.76
3.0
4.4
1.42
1.43
mmol/l
0.11
357
4923
382
2252
2.67
32.94
6.8
14.5
1.09
1.29
inr
6.36
105
645
115
390
3.36
27.47
1.9
6.6
6.23
9.48
mmol/l
8.06
108
371
225
1102
2.59
27.33
12.6
5.1
—
—
—
0
0
389
5125
0.41
26.63
2.9
4.0
1.31
1.32
mmol/l
0.14
353
4714
398
5190
0.40
26.39
3.9
4.5
5.93
5.97
mmol/l
0.17
354
4758
369
4959
0.41
26.22
3.7
5.7
38.82
39.85
mmol/mol
1.47
338
4619
326
1929
2.38
25.77
5.1
3.9
34.66
36.19
g/l
5.21
314
1778
246
1297
2.44
25.13
3.1
3.1
7.40
7.40
ph
0.23
38
203
152
654
2.73
23.58
2.0
2.8
0.87
0.82
mmol/l
4.37
147
608
508
3751
2.59
22.99
16.1
5.3
67.19
74.82
u/l
10.31
503
3462
93
315
3.28
22.06
6.1
6.1
—
—
—
0
0
90
304
3.27
21.42
7.7
8.7
24.93
24.71
mmol/l
0.30
85
292
41
1425
0.24
20.03
1.3
1.7
1.24
1.43
mmol/l
1.13
35
1203
55
141
4.17
19.61
7.8
9.1
1.95
1.27
mmol/l
1.77
50
128
111
445
2.80
19.48
2.1
1.7
301.76
364.76
nmol/l
2.64
101
413
324
2143
2.01
17.00
15.8
7.8
0.00
0.00
e9/l
1.76
242
1770
158
795
2.30
17.00
3.5
2.0
2.44
2.43
mmol/l
0.94
145
673
89
347
2.81
16.35
2.9
4.0
1.78
0.82
%
3.66
67
86
136
709
2.16
13.11
2.1
2.7
2.88
1.71
e6/l
0.81
73
379
204
1241
1.94
12.81
2.3
2.8
0.44
0.38
e6/l
0.19
150
932
20
13
15.82
12.68
1.4
1.6
0.08
0.17
e9/l
0.96
20
13
77
320
2.59
12.41
2.7
4.0
1.43
0.49
%
1.46
56
79
217
1364
1.88
12.24
2.4
2.9
30.27
90.69
e6/l
0.67
160
1041
206
1285
1.88
11.83
2.3
3.0
—
—
—
0
0
197
1217
1.89
11.63
2.2
2.7
—
—
—
0
0
80
1592
0.43
11.41
2.6
3.3
56.64
133.40
mg/l
0.68
51
1036
166
977
1.94
11.31
2.9
3.7
200.26
660.20
ng/l
1.45
121
753
23
834
0.25
11.25
1.1
1.2
1.03
8.78
u/ml
—
9
318
91
1708
0.46
11.05
2.4
3.2
9.01
8.04
mmol/l
0.70
75
1451
115
1978
0.49
10.84
2.1
2.8
—
—
—
0
0
90
1674
0.46
10.56
3.0
3.8
9.17
8.14
mg/mmol
0.09
46
1077
136
764
1.98
10.55
2.1
2.5
1.46
0.99
e6/l
0.42
72
432
538
5915
0.49
10.08
38.6
16.9
40.06
41.05
%
4.75
502
5501
539
5921
0.49
10.02
38.2
16.8
7.30
6.67
e9/l
7.82
519
5737
539
5921
0.49
10.02
38.2
16.8
4.41
4.59
e12/l
13.48
518
5737
539
5921
0.49
10.02
38.2
16.7
30.90
30.39
pg
9.89
534
5811
15
9
17.03
9.91
1.2
1.8
5.47
5.89
%
—
15
9
15
9
17.03
9.91
1.2
1.8
—
—
—
0
0
539
5917
0.49
9.83
38.3
16.8
232.45
246.85
e9/l
4.67
520
5744
29
82
3.65
9.04
2.6
3.6
2.56
2.35
mmol/l
0.14
22
51
72
335
2.29
9.04
3.0
4.1
0.14
0.08
%
0.48
50
73
34
875
0.36
8.55
1.1
1.3
12.42
37.06
iu/ml
—
6
265
228
1605
1.65
7.99
2.6
3.4
43.64
92.54
e6/l
1.39
163
1128
404
4738
0.61
7.97
3.8
4.4
1.72
2.16
mu/l
1.05
370
4326
19
31
6.28
7.59
1.4
1.8
37.29
41.49
%
0.52
19
31
42
170
2.57
7.15
6.1
2.8
0.17
0.25
g/l
0.90
37
61
141
2078
0.59
7.05
2.1
2.7
175.11
125.06
ug/l
1.09
123
1910
76
1335
0.51
7.05
1.9
2.2
6429.77
7084.87
umol/l
0.04
65
1170
86
1436
0.54
6.72
2.0
2.9
475.76
1266.88
ng/l
8.56
75
1207
316
3853
0.65
6.68
3.5
3.6
14.60
14.80
pmol/l
0.63
291
3500
309
3769
0.66
6.39
2.6
3.9
11.09
10.88
mm/h
0.09
282
3457
18
35
5.26
6.36
3.3
5.5
—
—
—
0
0
138
2002
0.61
6.30
1.8
2.2
73.37
76.54
nmol/l
0.69
126
1783
144
2065
0.61
6.26
3.1
3.5
2.30
1.78
ug/l
0.73
123
1859
14
22
6.48
5.88
1.1
1.2
—
—
—
0
0
8
316
0.24
5.81
1.0
1.3
90.13
313.91
u/ml
—
8
292
26
614
0.40
5.30
1.6
1.6
—
—
—
0
0
78
455
1.81
5.27
3.1
3.3
—
—
—
0
0
68
1139
0.55
5.22
3.1
3.5
1.02
1.02
kg/l
0.36
17
153
60
325
1.93
5.10
3.1
4.1
0.08
0.12
%
0.16
38
65
10
12
8.44
5.07
3.4
8.2
—
—
—
0
0
10
12
8.44
5.07
1.7
4.1
—
—
—
0
0
255
1994
1.46
5.02
3.3
3.5
16.57
75.97
ng/l
1.54
206
1377
152
2073
0.65
5.00
1.7
1.9
92.50
95.56
pmol/l
0.41
77
1056
23
84
2.80
4.82
1.9
3.4
—
—
—
0
0
130
897
1.56
4.64
2.4
2.5
557.09
537.44
mosm/kgh2o
0.47
116
754
68
1092
0.58
4.42
1.1
1.2
0.47
2.19
u/ml
3.17
14
312
35
679
0.49
4.26
1.0
1.2
—
—
—
0
0
76
1166
0.61
4.11
1.4
1.5
17.67
20.68
nmol/l
1.50
67
993
81
514
1.66
4.07
2.0
2.3
5.74
7.97
umol/l
0.90
71
440
512
5507
0.68
3.92
21.1
11.0
—
—
—
0
0
12
28
4.35
3.83
1.8
13.8
—
—
—
0
0
16
400
0.38
3.74
1.1
1.4
—
—
—
0
0
32
155
2.12
3.73
1.4
1.7
0.13
1.63
ug/l
3.21
27
140
78
1156
0.63
3.61
2.2
2.5
0.61
0.71
ug/l
1.06
48
715
70
442
1.65
3.60
2.0
3.0
2.20
2.20
mmol/l
0.01
65
367
90
1287
0.65
3.52
3.2
3.6
0.00
0.01
estimate
0.50
34
386
153
1973
0.71
3.46
2.6
3.1
6.04
5.82
ph
0.52
12
153
23
479
0.46
3.44
1.4
1.4
—
—
—
0
0
28
544
0.49
3.43
1.2
1.3
—
—
—
0
0
69
1039
0.62
3.41
1.4
1.7
474.60
32515056.78
pmol/l
1.19
57
855
20
82
2.48
3.41
1.7
2.4
20.22
16.70
%
—
5
45
7
10
7.06
3.37
1.0
1.0
—
—
—
0
0
41
227
1.86
3.32
2.2
1.5
3.45
2.73
ug/l
0.42
23
174
37
200
1.90
3.23
4.0
4.8
—
—
—
0
0
12
35
3.47
3.12
1.4
1.5
—
—
—
0
0
16
368
0.42
3.11
1.4
1.5
—
—
—
0
0
10
25
4.05
3.09
2.0
1.6
466.80
787.56
e6/l
—
10
25
5
5
10.06
2.98
1.0
1.0
—
—
—
0
0
381
3367
1.32
2.96
3.7
3.9
—
—
—
0
0
6
10
6.04
2.70
1.0
1.0
—
—
—
0
0
36
599
0.58
2.67
2.4
2.5
167.13
139.35
ug/g
0.23
31
477
5
7
7.19
2.55
1.4
1.0
—
—
—
0
0
5
7
7.19
2.55
1.4
1.0
—
—
—
0
0
5
7
7.19
2.55
1.4
1.0
—
—
—
0
0
6
11
5.49
2.55
1.0
1.1
—
—
—
0
0
201
2400
0.77
2.55
2.8
3.3
0.00
0.01
estimate
0.74
40
419
9
222
0.40
2.47
1.1
1.1
—
88.50
titre
—
0
6
203
2393
0.78
2.26
4.0
4.6
0.00
0.00
estimate
-0.00
37
395
194
1612
1.29
2.26
6.2
2.8
27.35
33.51
u/l
3.55
187
1525
88
1165
0.72
2.22
1.7
2.1
2.66
2.94
mg/l
0.51
70
973
123
1532
0.76
2.06
2.1
2.3
53.36
60.50
u/l
1.23
115
1411
69
937
0.71
2.03
1.1
1.3
1.98
2.63
g/l
4.07
36
577
8
26
3.10
2.02
1.1
1.1
34.31
33.96
mmol/l
—
8
26
50
338
1.52
2.01
1.3
1.3
—
55.10
—
0
21
32
507
0.61
1.99
1.1
1.3
—
—
—
0
0
19
98
1.97
1.97
2.2
2.0
15.29
62.34
u/ml
0.46
14
78
209
2424
0.80
1.96
2.8
3.3
0.00
0.01
estimate
0.50
35
382
9
199
0.44
1.86
1.1
1.1
—
—
—
0
0
8
28
2.88
1.86
3.3
2.5
—
—
—
0
0
5
135
0.37
1.77
1.2
1.2
—
2.77
—
0
16
12
244
0.48
1.77
1.3
1.6
—
—
—
0
0
34
514
0.64
1.75
1.2
1.4
—
—
—
0
0
117
943
1.29
1.70
2.2
2.2
7.06
4.73
e6/l
0.79
108
841
28
429
0.64
1.55
3.1
2.9
—
—
—
0
0
11
51
2.18
1.51
1.3
1.3
0.52
1.42
promille
1.37
11
41
20
327
0.60
1.46
1.1
1.2
—
—
—
0
0
7
28
2.52
1.45
1.4
1.8
—
—
—
0
0
34
230
1.50
1.42
2.0
2.2
0.66
0.63
%
0.24
34
230
17
96
1.79
1.40
1.1
1.1
—
—
—
0
0
41
292
1.43
1.34
2.9
2.6
—
—
—
0
0
9
42
2.16
1.34
3.3
2.4
—
—
—
0
0
0
41
0.00
1.31
0.0
1.2
—
1.30
—
0
24
16
267
0.59
1.29
1.4
1.2
—
—
—
0
0
108
1289
0.81
1.26
2.9
3.0
—
—
—
0
0
34
237
1.46
1.25
2.0
2.2
1.21
1.35
%
0.38
34
237
6
25
2.41
1.24
2.7
2.5
—
—
—
0
0
10
49
2.06
1.22
2.4
1.7
—
—
—
0
0
8
37
2.18
1.21
3.4
1.7
16.75
20.25
nmol/l
—
8
31
8
152
0.52
1.15
1.5
1.6
—
—
—
0
0
167
1464
1.19
1.13
3.6
3.8
—
—
—
0
0
16
255
0.62
1.10
1.1
1.1
—
—
—
0
0
9
163
0.55
1.10
1.4
1.1
—
—
—
0
0
8
41
1.96
1.09
1.0
1.4
13.41
11.20
%
—
8
41
11
191
0.57
1.05
1.2
1.2
—
0.31
—
0
12
10
178
0.55
1.04
1.7
1.6
—
—
—
0
0
96
1135
0.82
1.03
2.3
3.4
—
—
—
0
0
7
34
2.07
1.03
1.0
1.2
—
—
—
0
0
69
558
1.26
1.02
1.5
1.7
—
—
—
0
0
14
225
0.61
1.01
1.4
1.9
43.36
37.66
nmol/l
0.60
14
218
0
30
0.00
0.97
0.0
1.1
—
227.62
—
0
30
11
185
0.59
0.95
1.1
1.2
—
—
—
0
0
35
463
0.74
0.94
1.7
2.4
15.69
14.84
nmol/l
0.23
30
426
6
28
2.15
0.91
1.5
2.3
—
—
—
0
0
5
104
0.48
0.89
1.0
1.9
4.21
5.10
mmol/24h
—
5
93
8
42
1.92
0.89
1.3
1.3
—
—
—
0
0
10
56
1.80
0.88
1.0
1.1
—
—
—
0
0
8
43
1.87
0.87
2.5
2.6
—
—
—
0
0
30
396
0.75
0.82
1.0
1.2
—
—
—
0
0
76
896
0.83
0.81
1.6
1.7
980.74
1185.59
nmol/l
1.50
53
677
12
188
0.63
0.81
5.8
8.2
—
—
—
0
0
32
242
1.34
0.80
2.5
2.8
25.58
25.24
mmol/l
0.30
32
233
9
151
0.59
0.79
2.0
1.8
—
—
—
0
0
0
24
0.00
0.79
0.0
1.3
—
181.44
—
0
24
0
24
0.00
0.79
0.0
1.2
—
—
—
0
0
51
623
0.80
0.77
1.4
2.3
2.28
2.33
g/l
0.23
46
581
39
306
1.29
0.77
2.1
2.7
137.90
133.12
g/l
0.95
39
300
47
576
0.80
0.74
1.5
2.4
26.26
24.31
%
0.37
39
493
7
39
1.80
0.72
1.4
1.4
—
—
—
0
0
7
39
1.80
0.72
1.0
1.1
—
—
—
0
0
22
160
1.39
0.71
1.1
1.1
—
—
—
0
0
5
27
1.86
0.68
1.0
3.4
343.80
676.26
u/ml
—
5
27
18
127
1.43
0.68
4.1
3.0
—
—
—
0
0
42
341
1.25
0.65
1.1
1.5
—
—
—
0
0
17
122
1.40
0.60
3.1
4.3
—
—
—
0
0
0
20
0.00
0.60
0.0
3.2
—
29.10
—
0
5
12
80
1.51
0.60
2.6
2.9
5.85
4.29
e9/l
0.57
12
80
6
35
1.72
0.58
1.3
1.1
—
—
—
0
0
12
81
1.49
0.57
2.8
3.2
64.25
57.32
%
0.73
12
81
25
316
0.78
0.54
1.1
1.2
113.92
117.94
iu/ml
—
6
134
532
5200
1.12
0.54
25.7
11.4
17.65
22.89
mg/l
6.80
509
3932
45
378
1.20
0.53
1.2
1.1
—
—
—
0
0
10
66
1.52
0.52
4.1
2.1
—
—
—
0
0
18
135
1.34
0.51
1.2
1.1
—
—
—
0
0
6
41
1.47
0.50
1.0
1.1
—
—
—
0
0
364
3501
1.09
0.50
3.9
3.0
66.66
47.26
u/l
1.22
349
3271
10
68
1.48
0.47
4.1
2.1
103.70
105.66
mmol/l
—
10
68
10
68
1.48
0.47
4.1
2.1
4.08
4.06
mmol/l
—
10
68
12
86
1.40
0.44
1.1
1.2
—
—
—
0
0
17
130
1.32
0.44
1.6
1.2
17.58
24.29
iu/l
0.51
17
108
13
95
1.38
0.44
1.2
1.1
212.93
271.41
u/ml
—
8
54
36
424
0.84
0.43
1.2
1.8
—
—
—
0
0
14
105
1.34
0.41
1.2
2.5
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
37.45
—
0
11
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.6
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
0
17
0.00
0.40
0.0
1.2
—
—
—
0
0
28
234
1.21
0.38
1.8
3.4
—
—
—
0
0
15
191
0.78
0.37
2.1
1.7
—
—
—
0
0
6
87
0.69
0.33
1.2
1.0
—
—
—
0
0
25
293
0.85
0.30
1.1
1.4
—
—
—
0
0
21
250
0.83
0.30
2.1
2.3
—
—
—
0
0
15
120
1.26
0.30
2.5
2.3
—
—
—
0
0
12
94
1.28
0.28
1.6
1.9
—
—
—
0
0
11
139
0.79
0.27
1.2
2.1
29.63
11.53
mg/l
0.46
11
130
5
73
0.68
0.26
1.0
1.0
1.41
1.49
g/l
—
5
68
19
161
1.19
0.24
1.4
1.6
—
—
—
0
0
54
495
1.10
0.24
1.4
2.5
3.67
7.90
ug/l
3.95
46
439
0
11
0.00
0.21
0.0
1.0
—
16.52
—
0
11
0
10
0.00
0.21
0.0
6.1
—
—
—
0
0
0
10
0.00
0.21
0.0
2.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
7.9
—
—
—
0
0
0
12
0.00
0.21
0.0
4.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
0.80
—
0
7
0
13
0.00
0.21
0.0
1.0
—
10.83
—
0
7
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
7.9
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
1.36
—
0
14
43
395
1.09
0.19
2.0
3.3
53.97
186.31
ng/l
8.51
36
364
56
601
0.93
0.19
1.3
1.5
—
—
—
0
0
361
3674
0.96
0.18
3.0
3.7
—
—
—
0
0
7
59
1.19
0.18
1.4
1.1
—
—
—
0
0
39
358
1.10
0.18
1.6
2.2
0.28
0.21
g/l
4.13
39
320
7
60
1.17
0.18
1.4
1.4
—
—
—
0
0
16
138
1.16
0.17
1.3
2.0
—
—
—
0
0
27
243
1.12
0.17
3.3
2.6
0.86
0.17
e6/l
0.52
27
233
7
63
1.11
0.17
3.6
1.3
21.83
58.26
mu/l
—
7
58
8
68
1.18
0.16
1.3
1.3
—
—
—
0
0
27
245
1.11
0.15
4.3
3.2
—
—
—
0
0
6
80
0.75
0.15
1.0
1.0
—
—
—
0
0
9
80
1.13
0.15
1.3
1.1
—
—
—
0
0
9
81
1.11
0.15
1.3
1.1
—
—
—
0
0
7
87
0.80
0.14
1.0
1.4
—
—
—
0
0
7
87
0.80
0.14
1.3
1.2
—
—
—
0
0
7
87
0.80
0.14
1.0
1.4
—
—
—
0
0
7
89
0.78
0.14
1.0
1.5
—
—
—
0
0
10
84
1.19
0.14
1.2
2.4
—
—
—
0
0
46
432
1.07
0.13
2.1
2.2
33.97
31.49
u/l
0.33
39
359
15
132
1.14
0.13
1.3
1.3
7.35
7.62
u/l
0.04
15
109
71
678
1.05
0.13
1.4
2.0
—
—
—
0
0
57
544
1.05
0.11
1.2
1.6
—
—
—
0
0
53
505
1.05
0.10
1.8
2.0
2.08
1.69
%
1.06
45
446
21
194
1.09
0.09
1.4
1.7
—
—
—
0
0
64
664
0.96
0.09
1.3
1.6
—
—
—
0
0
6
56
1.07
0.08
1.5
1.4
—
—
nmol/l
—
0
0
7
64
1.09
0.08
1.4
1.4
1.09
0.69
nmol/l
—
7
59
88
856
1.03
0.08
1.4
1.9
—
—
—
0
0
6
75
0.80
0.07
1.2
1.2
—
—
—
0
0
8
75
1.07
0.07
1.1
2.7
—
—
—
0
0
22
206
1.07
0.07
1.4
1.7
—
—
—
0
0
22
207
1.06
0.06
1.4
1.7
—
—
—
0
0
109
1072
1.02
0.05
1.5
1.6
2.76
1.04
mg/l
1.54
87
804
21
203
1.04
0.01
1.3
1.7
—
—
—
0
0
21
204
1.03
0.00
1.4
1.7
—
—
—
0
0
34
335
1.02
0.00
1.8
1.6
65.38
67.82
g/l
0.85
29
302
37
373
0.99
0.00
2.9
3.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
5
51
0.98
-0.00
1.0
2.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
2.00
—
0
5
0
7
0.00
-0.00
0.0
1.3
—
69.86
—
0
7
5
52
0.96
-0.00
2.2
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
15.83
—
0
6
37
370
1.00
-0.00
1.9
2.0
69.26
67.85
e9/l
0.07
22
284
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
2.42
—
0
8
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: C3_GBM_ASTROCYTOMA – Brain glioblastoma and astrocytoma

GWS hits: 3

This endpoint is excluded from FinRegistry analyses (omitted endpoint).