Brain astrocytoma, including Hilmo

C3_ASTROCYTOMA_WIDE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

  • HLP_C3_ASTROCYTOMA
157

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 C71
  • Hospital discharge: ICD-9 191
  • Hospital discharge: ICD-8 191
  • Cause of death: ICD-10 C71
  • Cause of death: ICD-9 191
  • Cause of death: ICD-8 191
  • Cancer registry: Topography ICD-O-3 C71
  • Cancer registry: Morphology ICD-O-3 9400
  • Cancer registry: Behaviour codes 3

3 out of 7 registries used, show all original rules.

157

4. Check minimum number of events

None

157

5. Include endpoints

157

6. Filter based on genotype QC (FinnGen only)

151

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE
Control conditions
not HLP_C3_ASTROCYTOMA

Extra metadata

First used in FinnGen datafreeze
DF12

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 151 73 78
Unadjusted period prevalence (%) 0.03 0.03 0.04
Median age at first event (years) 39.55 38.15 40.85

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
157
Matched controls
1570
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
185.7
223.8
123
30
N03AX14
ATC
levetiracetam; systemic
239.0
193.9
95
10
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
193.9
174.7
87
10
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
71.7
166.3
114
56
130
Kela drug reimbursment
Malignant tumour
+∞
161.7
126
*
L01AX03
ATC
temozolomide; systemic
+∞
148.5
118
*
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
1626.4
146.3
120
*
H02AB02
ATC
dexamethasone; systemic
525.1
131.8
115
8
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
54.7
103.4
63
19
A04AA02
ATC
granisetron; systemic, transdermal
1949.3
102.1
88
*
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
84.1
100.6
55
10
C71.11
ICD-10 Finland
Malignant tumor of frontal lobe grade II glioma
+∞
88.0
76
*
A03FA01
ATC
metoclopramide; systemic, rectal
20.6
86.3
99
120
N03AF02
ATC
oxcarbazepine; oral
31.8
82.5
60
30
XX3DW
NOMESCO Finland
Time consuming IT work
33.3
78.2
55
25
WF002
NOMESCO Finland
Radical radiotherapy
1143.9
74.6
67
*
A04AA01
ATC
ondansetron; systemic, rectal
39.0
71.9
47
17
R56.8
ICD-10 Finland
Other and unspecified convulsions
23.0
69.4
58
39
C71.10
ICD-10 Finland
Malignant tumor in frontal lobe without histology
+∞
68.9
61
*
9400/3-C71.9
ICD-O-3
Astrocytoma, NOS, of brain, NOS
+∞
64.0
57
*
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
148.4
62.5
63
7
D43.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, supratentorial
455.0
62.0
58
*
9400/3-C71.1
ICD-O-3
Astrocytoma, NOS, of frontal lobe
+∞
59.2
53
*
AA1AD
NOMESCO Finland
CT of head and brain
12.6
58.7
101
197
XA800
NOMESCO Finland
Neuropsychological investigation
19.9
58.1
51
37
C71.21
ICD-10 Finland
Malignant tumor of temporal lobe grade II glioma
+∞
54.4
49
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
53.2
48
*
G40.9
ICD-10 Finland
Epilepsy, unspecified
26.6
50.2
37
18
ZXC95
NOMESCO Finland
Use of surgical navigator
145.1
49.2
50
5
AAG50
NOMESCO Finland
Stereotactic intracranial radiotherapy
+∞
45.0
41
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
40.4
37
*
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
10.3
40.2
56
80
C71.20
ICD-10 Finland
Malignant tumor in temporal lobe without histology
+∞
36.9
34
*
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
+∞
34.7
32
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
7.7
32.9
62
123
Z51.5
ICD-10 Finland
Palliative care
66.1
31.9
36
7
N03AX18
ATC
lacosamide; systemic
79.6
29.2
32
5
9400/3-C71.2
ICD-O-3
Astrocytoma, NOS, of temporal lobe
+∞
27.9
26
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
323.5
27.6
27
*
WZC00
NOMESCO Finland
Treatment plan or consultation
5.8
27.2
90
295
C71.12
ICD-10 Finland
Malignant tumor of frontal lobe grade III glioma
+∞
26.8
25
*
AAG00
NOMESCO Finland
Stereotactic intracranial biopsy
+∞
26.8
25
*
ZXC40
NOMESCO Finland
Use of ultrasound
161.8
26.5
27
*
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
67.5
25.0
28
5
C71.1
ICD-10 Finland
Malignant neoplasm: Frontal lobe
+∞
24.6
23
*
C71.2
ICD-10 Finland
Malignant neoplasm: Temporal lobe
+∞
22.4
21
*
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
253.9
22.2
22
*
WX882
NOMESCO Finland
High dependency care
42.1
20.5
25
7
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
120.4
20.1
21
*
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
227.5
20.0
20
*
N03AG01
ATC
valproic acid; systemic, rectal
7.5
19.3
31
50
C71.90
ICD-10 Finland
Malignant tumor in unspecified localization in the brain without histology
+∞
19.1
18
*
D43.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Central nervous system, unspecified
+∞
19.1
18
*
N03AB02
ATC
phenytoin; systemic
42.2
18.2
22
6
C71.22
ICD-10 Finland
Malignant tumor of temporal lobe grade III glioma
+∞
18.1
17
*
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
33.3
18.0
23
8
YX8VG
NOMESCO Finland
Stereotactic MRI exmaination with high intensity magnet for dose design of radiotherapy
+∞
17.0
16
*
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
189.3
16.8
17
*
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
34.3
16.6
21
7
A02BC02
ATC
pantoprazole; systemic
4.7
16.0
123
681
C71.31
ICD-10 Finland
Malignant tumor of the parietal lobe grand II glioma
+∞
15.9
15
*
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
+∞
15.9
15
*
WX402
NOMESCO Finland
General anaesthesia
4.2
15.1
53
170
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
88.6
14.9
16
*
ZX050
NOMESCO Finland
Stereotactic radiotherapy
+∞
14.8
14
*
YA1VG
NOMESCO Finland
MRI examination of head and neck with high intesity magnet for dose design of radiotherapy
164.7
14.7
15
*
N05BA09
ATC
clobazam; oral
30.6
14.7
19
7
ZXE20
NOMESCO Finland
More than three and less than five hours
5.5
14.5
32
70
N02AA05
ATC
oxycodone; systemic
5.5
14.5
32
70
WZC30
NOMESCO Finland
Teaching
4.9
14.3
37
93
YX8BD
NOMESCO Finland
Stereotactic extensive CT examination for dose design of radiotherapy
+∞
13.7
13
*
C71.29
ICD-10 Finland
Malignant tumor in temporal lobe other or unspecified histology
+∞
13.7
13
*
C71.19
ICD-10 Finland
Malignant tumor of frontal lobe other or unspecified histology
+∞
12.7
12
*
WF029
NOMESCO Finland
Radiotherapy of local residive tumor
+∞
12.7
12
*
C71.01
ICD-10 Finland
Malignant tumor of cerebellum except lobes and ventricles grade II glioma
+∞
12.7
12
*
C71.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of brain
+∞
12.7
12
*
H53.4
ICD-10 Finland
Visual field defects
23.6
12.3
17
8
N03AF01
ATC
carbamazepine; oral, rectal
10.6
12.0
23
25
G40.10
ICD-10 Finland
Simple partial seizures
70.4
11.8
13
*
WX408
NOMESCO Finland
General anesthesy, balanced
3.5
11.7
53
198
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
+∞
11.6
11
*
C71.23
ICD-10 Finland
Malignant tumor of temporal lobe grade IV glioma
+∞
11.6
11
*
C71.30
ICD-10 Finland
Malignant tumor in parietal lobe without histology
+∞
11.6
11
*
R4150
NOMESCO Finland
Neuropsychological rehabilitation
18.9
11.5
17
10
WC105
NOMESCO Finland
Simple cytostatic therapy of local tumor recidive
+∞
10.5
10
*
ZX070
NOMESCO Finland
Intensity modified radiotherapy
+∞
10.5
10
*
C71.99
ICD-10 Finland
Malignant tumor in unspecified localization in the brain other or unspecified histology
+∞
10.5
10
*
C71.81
ICD-10 Finland
Overall malignant tumor of the brain grade II glioma
+∞
10.5
10
*
AAA10
NOMESCO Finland
Biopsy through craniotomy
+∞
10.5
10
*
ZXM40
NOMESCO Finland
Use of fluorescent substance
+∞
10.5
10
*
C71.13
ICD-10 Finland
Malignant tumor of frontal lobe grade IV glioma
+∞
10.5
10
*
N05CD08
ATC
midazolam; nasal, systemic
20.5
10.5
15
8
WX872
NOMESCO Finland
Intensive care
8.5
9.8
21
28
ZX090
NOMESCO Finland
Other technic of radiotherapy
58.7
9.8
11
*
N03AX23
ATC
brivaracetam; systemic
106.2
9.5
10
*
9400/3-C71.0
ICD-O-3
Astrocytoma, NOS, of cerebrum
+∞
9.5
9
*
AA1BD
NOMESCO Finland
Extensive CT of head and brain
16.9
9.2
14
9
183
Kela drug reimbursment
Lamotrigin and topiramate
15.2
8.9
14
10
WX404
NOMESCO Finland
Intravenous generell anesthesy
3.2
8.8
41
154
R90.8
ICD-10 Finland
Other abnormal findings on diagnostic imaging of central nervous system
17.6
8.7
13
8
G91.1
ICD-10 Finland
Obstructive hydrocephalus
94.9
8.5
9
*
D43.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, unspecified
94.9
8.5
9
*
ZSA00
NOMESCO Finland
Procedure related to previous procedure classified in chapter A
+∞
8.4
8
*
ZXE30
NOMESCO Finland
More than five and less than seven hours
9.8
8.3
16
18
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
35.4
8.2
10
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.4
7.4
29
97
9400/3-C71.3
ICD-O-3
Astrocytoma, NOS, of parietal lobe
+∞
7.3
7
*
C71.00
ICD-10 Finland
Malignant tumor of the cerebrum except lobes and ventricles without histology
+∞
7.3
7
*
N76
ICPC
Neoplasm nervous system unspecified
+∞
7.3
7
*
R4120
NOMESCO Finland
Occupational therapy
4.5
7.3
19
47
G40
ICD-10 Finland
Epilepsy
14.7
7.0
11
8
R47.0
ICD-10 Finland
Dysphasia and aphasia
17.7
6.8
10
6
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
23.7
6.8
9
*
XX9BW
NOMESCO Finland
Submitting image material and/or investigation material to authority or other institution
23.7
6.8
9
*
D33.00
ICD-10 Finland
Medial pilosytic astrocytoma of the cerebrum
72.7
6.5
7
*
R4130
NOMESCO Finland
Speech therapy
8.7
6.5
13
16
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
3.1
6.5
31
117
H02AB09
ATC
hydrocortisone; systemic
9.9
6.4
12
13
Z73.3
ICD-10 Finland
Stress, not elsewhere classified
27.9
6.3
8
*
C71.80
ICD-10 Finland
Overall malignant tumor of the brain without histology
+∞
6.3
6
*
A79
ICPC
Malignancy NOS
+∞
6.3
6
*
C71.82
ICD-10 Finland
Overall malignant tumor of the brain grade III glioma
+∞
6.3
6
*
C71.40
ICD-10 Finland
Malignant tumor of the occipital lobe without histology
+∞
6.3
6
*
C71.91
ICD-10 Finland
Malignant tumor in unspecified location in the brain grade II glioma
+∞
6.3
6
*
AA5NK
NOMESCO Finland
Tractography within white matter of central nervous system
+∞
6.3
6
*
R4110
NOMESCO Finland
Physiotherapy
2.6
6.2
46
219
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.7
6.1
20
59

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
89
28
72.08
147.56
1.4
1.3
—
—
—
0
0
82
89
18.19
75.55
5.4
15.0
0.82
1.60
mmol/l
1.05
63
71
60
42
22.50
70.42
4.1
7.7
24.02
25.14
mmol/l
0.93
60
42
41
46
11.71
34.98
5.3
14.4
96.78
93.78
%
5.26
41
46
120
461
7.80
31.48
6.6
6.4
1.20
1.21
mmol/l
1.75
108
406
103
392
5.73
25.73
3.3
1.6
—
—
—
0
0
96
345
5.59
25.69
2.1
1.9
—
—
—
0
0
114
524
5.29
21.20
2.5
2.4
—
—
—
0
0
77
294
4.18
17.55
7.9
2.0
2.38
2.35
mmol/l
1.60
70
254
33
67
5.97
16.31
6.5
10.0
—
—
—
0
0
124
694
4.74
15.75
16.3
6.7
3.43
4.20
e9/l
4.14
105
607
26
44
6.88
15.34
6.9
22.8
—
—
—
0
0
86
401
3.53
13.76
4.0
8.9
1.04
1.20
inr
2.71
22
113
105
567
3.57
13.04
10.1
5.8
—
—
—
0
0
21
17
14.06
12.55
2.0
1.4
—
—
—
0
0
109
627
3.42
11.72
9.5
6.1
0.11
0.19
e9/l
12.20
90
562
107
609
3.38
11.70
9.5
5.7
0.53
0.55
e9/l
0.44
88
541
107
609
3.38
11.70
9.5
5.7
0.02
0.04
e9/l
5.83
87
541
24
50
5.49
11.38
5.4
15.1
—
—
—
0
0
99
561
3.07
10.48
9.6
6.0
0.46
0.67
%
4.06
99
526
101
579
3.09
10.47
9.9
6.2
9.32
8.31
%
2.70
101
552
77
381
3.00
10.42
1.3
1.6
—
—
—
0
0
100
575
3.04
10.22
9.7
5.8
1.96
2.90
%
5.89
100
546
106
631
3.09
10.14
9.7
5.8
1.43
1.91
e9/l
9.91
88
569
19
36
5.87
9.91
1.7
1.1
34.29
2.48
e6/l
1.22
14
27
101
591
2.99
9.87
9.7
5.7
60.59
56.78
%
2.14
101
564
17
15
12.55
9.83
1.9
1.3
—
—
—
0
0
101
599
2.92
9.48
9.9
5.8
25.71
29.29
%
2.31
101
573
21
31
7.65
9.21
1.9
1.2
—
—
—
0
0
59
279
2.79
8.33
2.5
2.6
7.41
7.40
ph
—
9
29
88
509
2.66
8.30
12.7
7.2
0.00
0.00
e9/l
0.48
66
412
50
229
2.74
7.39
3.3
3.8
—
—
—
0
0
54
278
2.44
6.14
9.0
5.5
—
—
—
0
0
9
6
15.79
5.98
1.8
4.0
—
—
—
0
0
9
6
15.79
5.98
3.6
8.0
—
—
—
0
0
101
1263
0.44
5.42
2.8
3.7
4.88
4.71
mmol/l
0.83
91
1197
101
1258
0.45
5.18
2.8
3.6
1.38
1.42
mmol/l
0.41
91
1190
103
1273
0.45
5.15
2.8
3.9
3.06
2.87
mmol/l
1.23
91
1199
45
245
2.17
4.31
3.2
3.2
—
—
—
0
0
61
382
1.98
3.98
2.6
2.8
13.30
36.90
ng/l
1.90
41
202
99
1212
0.50
3.93
2.7
3.3
1.34
1.27
mmol/l
0.32
89
1134
20
81
2.68
3.63
3.4
3.8
—
—
—
0
0
9
17
5.55
3.56
2.0
1.2
—
—
—
0
0
12
32
3.97
3.47
3.4
5.8
—
—
—
0
0
0
80
0.00
3.03
0.0
1.2
—
473.02
—
0
74
12
280
0.38
2.77
2.4
4.0
1.77
9.42
mg/mmol
—
6
188
17
75
2.42
2.62
3.8
4.0
1.60
0.53
%
—
10
17
7
16
4.53
2.50
3.1
2.1
8.81
8.44
kpa
—
7
16
7
16
4.53
2.50
3.1
2.1
5.19
4.85
kpa
—
7
16
7
16
4.53
2.50
3.1
2.1
2.27
1.95
mmol/l
—
7
10
141
1256
2.20
2.39
22.8
10.5
139.11
139.71
mmol/l
1.50
141
1223
12
47
2.68
2.33
3.5
2.7
1.22
1.22
mmol/l
0.26
12
39
141
1260
2.17
2.30
22.0
10.6
3.90
3.95
mmol/l
1.60
141
1224
28
160
1.91
2.29
2.6
2.3
4.28
2.53
e6/l
0.27
16
80
93
1104
0.61
2.26
3.1
4.6
35.74
38.58
mmol/mol
4.92
82
1053
5
9
5.69
2.23
1.4
1.1
93.04
91.83
%
—
5
9
26
147
1.92
2.19
1.2
1.6
—
—
—
0
0
101
1170
0.62
2.12
3.6
3.5
5.46
5.75
mmol/l
2.86
92
1084
90
724
1.57
2.03
3.3
3.7
—
48.10
—
0
10
0
52
0.00
1.92
0.0
1.1
—
—
—
0
0
6
17
3.63
1.85
2.8
2.0
—
—
—
0
0
39
265
1.63
1.77
2.2
2.6
—
—
—
0
0
12
233
0.47
1.72
1.7
1.4
—
—
—
0
0
10
43
2.41
1.62
2.4
1.8
21.10
20.84
s
—
10
37
14
71
2.07
1.59
3.4
4.1
0.14
0.08
%
—
7
12
89
743
1.46
1.51
2.8
2.9
—
—
—
0
0
6
137
0.42
1.49
1.0
1.2
—
—
—
0
0
40
286
1.53
1.46
2.5
2.4
0.15
0.21
e6/l
0.30
29
215
38
511
0.66
1.39
1.8
2.3
—
—
—
0
0
40
290
1.51
1.37
2.1
2.3
—
—
—
0
0
139
1285
1.71
1.33
20.6
9.7
19.48
20.53
mg/l
0.20
130
961
30
205
1.57
1.33
2.0
3.2
1555.67
687.57
ng/l
0.22
12
132
94
805
1.42
1.31
3.1
3.8
—
—
—
0
0
8
36
2.29
1.26
1.1
1.3
—
—
—
0
0
16
94
1.78
1.23
1.3
1.3
—
31.68
—
0
5
0
35
0.00
1.16
0.0
1.1
—
—
—
0
0
0
35
0.00
1.16
0.0
1.6
—
—
—
0
0
14
227
0.58
1.13
1.2
1.3
—
—
—
0
0
42
324
1.40
1.04
2.5
2.3
23.92
255.20
e6/l
0.61
31
250
141
1470
0.60
1.01
35.1
14.4
40.26
41.46
%
1.96
135
1397
12
69
1.80
0.99
3.3
4.1
1.10
0.37
%
—
5
16
17
252
0.64
0.96
1.2
1.8
—
—
—
0
0
12
70
1.77
0.95
3.3
4.1
0.00
0.08
%
—
5
13
9
152
0.57
0.94
2.2
2.0
—
—
—
0
0
142
1473
0.62
0.85
35.5
14.4
136.11
139.87
g/l
2.69
142
1452
112
1206
0.75
0.83
31.4
12.7
336.54
334.51
g/l
1.37
112
1201
142
1472
0.63
0.82
34.5
14.3
90.71
90.07
fl
1.07
142
1452
142
1472
0.63
0.82
34.4
14.3
30.54
30.19
pg
1.82
142
1452
0
24
0.00
0.80
0.0
1.1
—
—
—
0
0
11
172
0.61
0.79
2.3
2.4
0.65
0.75
ug/l
—
6
94
6
34
1.79
0.77
1.5
1.2
—
—
—
0
0
6
34
1.79
0.77
1.5
1.2
—
—
—
0
0
22
292
0.71
0.72
1.0
1.3
1.69
2.33
g/l
—
10
175
11
69
1.64
0.70
1.4
2.5
0.27
0.22
g/l
0.88
11
62
8
50
1.63
0.62
1.4
3.0
—
7.42
—
0
5
10
147
0.66
0.57
1.1
1.4
—
—
—
0
0
50
569
0.82
0.50
2.9
2.9
0.00
0.01
estimate
0.50
11
101
11
76
1.48
0.49
1.9
2.6
—
—
—
0
0
8
116
0.67
0.48
1.1
1.3
—
—
—
0
0
50
565
0.83
0.46
4.2
4.1
0.00
0.00
estimate
—
9
94
108
1141
0.83
0.46
3.8
4.3
1.64
1.74
mu/l
0.65
102
1064
9
126
0.70
0.45
1.3
1.5
—
—
—
0
0
9
126
0.70
0.45
1.4
1.5
—
—
—
0
0
10
69
1.48
0.45
2.0
2.3
—
—
—
0
0
51
572
0.84
0.43
2.9
3.0
0.00
0.00
estimate
—
9
92
21
258
0.79
0.42
2.7
2.9
—
—
—
0
0
0
15
0.00
0.41
0.0
1.3
—
76.80
—
0
15
0
15
0.00
0.41
0.0
3.9
—
—
—
0
0
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
7
105
0.65
0.41
2.1
1.6
—
—
—
0
0
5
35
1.44
0.39
1.6
2.9
—
—
—
0
0
5
36
1.40
0.38
2.4
10.2
—
—
—
0
0
9
68
1.34
0.38
1.7
1.3
18.59
21.95
iu/l
—
9
62
11
145
0.74
0.36
1.2
2.2
—
—
—
0
0
5
79
0.62
0.36
1.0
1.2
—
—
—
0
0
44
390
1.18
0.36
2.8
2.8
49.74
65.91
e6/l
0.15
32
267
7
100
0.69
0.31
2.1
1.5
—
—
—
0
0
8
106
0.74
0.30
2.0
1.6
—
—
—
0
0
7
57
1.24
0.29
1.7
1.4
10.24
6.30
u/l
—
7
47
8
63
1.28
0.28
1.1
1.1
—
—
—
0
0
17
141
1.23
0.27
1.9
1.6
1369.33
1073.21
nmol/l
—
9
111
5
72
0.68
0.26
1.0
1.4
—
—
—
0
0
5
72
0.68
0.26
1.0
1.4
—
—
—
0
0
5
74
0.67
0.26
1.0
1.5
—
—
—
0
0
52
562
0.89
0.25
2.0
2.7
84.45
84.77
ug/l
0.01
46
531
25
220
1.16
0.23
1.4
1.6
—
—
—
0
0
38
415
0.89
0.21
1.7
2.1
—
—
—
0
0
8
105
0.75
0.21
1.9
1.6
—
—
—
0
0
8
105
0.75
0.21
2.0
1.6
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
153.46
—
0
12
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
9.9
—
0.62
—
0
13
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
2.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
141
1385
1.18
0.19
17.8
7.6
28.65
28.30
u/l
0.08
141
1345
26
286
0.89
0.16
3.1
3.2
0.00
0.00
estimate
—
9
94
9
78
1.16
0.15
1.7
2.3
8.77
10.14
ug/l
—
9
69
112
1145
0.92
0.13
29.1
11.7
13.32
14.32
%
6.78
112
1130
31
332
0.92
0.12
2.8
2.6
—
—
—
0
0
14
124
1.14
0.11
1.0
1.2
—
—
—
0
0
136
1378
0.90
0.11
19.9
8.8
—
—
—
0
0
5
43
1.17
0.10
1.0
1.1
—
—
—
0
0
5
46
1.09
0.09
5.6
2.7
—
—
—
0
0
6
72
0.83
0.08
1.7
1.8
—
—
—
0
0
7
82
0.85
0.07
2.0
1.3
—
—
—
0
0
14
131
1.08
0.03
1.3
1.8
—
—
—
0
0
38
389
0.97
0.02
1.7
1.8
94.05
98.57
pmol/l
0.26
22
195
27
263
1.03
0.01
1.4
1.7
0.89
0.90
mg/l
0.01
16
194
15
149
1.01
0.00
2.1
2.3
11.90
6.46
umol/l
—
10
130
32
325
0.98
0.00
1.4
1.7
—
—
—
0
0
11
108
1.02
0.00
1.3
1.1
—
—
—
0
0
91
914
0.99
0.00
3.4
3.8
14.35
14.55
pmol/l
0.33
85
853
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
155.83
—
0
6
0
9
0.00
-0.00
0.0
4.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
4.7
—
8.07
—
0
7
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
3.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
206.14
—
0
7
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
14.95
—
0
8
0
8
0.00
-0.00
0.0
1.0
—
293.25
—
0
8
0
6
0.00
-0.00
0.0
4.2
—
3.55
—
0
6
9
91
0.99
-0.00
2.9
2.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: C3_ASTROCYTOMA_WIDE – Brain astrocytoma, including Hilmo

GWS hits: 1

This endpoint is excluded (different definition than used in FinnGen).