This is a non-core endpoint: only basic statistics are computed.
See its core counterpart C3_BRAIN_EXALLC for full statistics.
Malignant neoplasm of brain
C3_BRAIN
brain neoplasm: A neoplasm (disease) that involves the brain.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1240 |
4. Check minimum number of eventsNone |
1240 |
5. Include endpointsNone |
1240 |
6. Filter based on genotype QC (FinnGen only) |
1240 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF9
Similar endpoints
↥List of similar endpoints to
Malignant neoplasm of brain
based on the number of shared cases.
Similar with more cases:
- Malignant neoplasm of eye, brain and central nervous system
- Malignant neoplasm of brain, excluding all cancers (controls excluding all cancers)
- Malignant neoplasm of eye, brain and central nervous system, excluding all cancers (controls excluding all cancers)
- Malignant neoplasm
- Any event in cancer register
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1240 | 541 | 699 |
| Unadjusted period prevalence (%) | 0.25 | 0.18 | 0.31 |
| Median age at first event (years) | 57.76 | 54.38 | 60.38 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1136
- Matched controls
- 11359
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L01AX03
ATC
temozolomide; systemic
2133.0
323.0
605
6
N03AX14
ATC
levetiracetam; systemic
92.7
323.0
511
99
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
35.0
323.0
657
428
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
1196.0
323.0
711
16
D43.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, supratentorial
541.4
323.0
338
9
H02AB02
ATC
dexamethasone; systemic
65.1
323.0
851
497
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
43.2
323.0
570
258
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
89.1
323.0
408
71
130
Kela drug reimbursment
Malignant tumour
42.2
323.0
712
434
A04AA02
ATC
granisetron; systemic, transdermal
25.2
282.7
415
253
C71.10
ICD-10 Finland
Malignant tumor in frontal lobe without histology
858.3
281.0
265
*
ZXC95
NOMESCO Finland
Use of surgical navigator
102.7
254.4
274
35
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
34.3
243.9
323
130
C71.20
ICD-10 Finland
Malignant tumor in temporal lobe without histology
+∞
222.4
206
*
A03FA01
ATC
metoclopramide; systemic, rectal
8.8
219.4
594
1261
WF002
NOMESCO Finland
Radical radiotherapy
19.9
217.4
344
242
C71.90
ICD-10 Finland
Malignant tumor in unspecified localization in the brain without histology
1246.5
217.0
205
*
AAG50
NOMESCO Finland
Stereotactic intracranial radiotherapy
257.0
210.4
210
10
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
42.6
207.0
259
78
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
36.0
195.0
254
90
WF003
NOMESCO Finland
Adjuvant radiotherapy
26.5
194.1
276
136
C71.11
ICD-10 Finland
Malignant tumor of frontal lobe grade II glioma
2217.3
188.9
178
*
C71.23
ICD-10 Finland
Malignant tumor of temporal lobe grade IV glioma
+∞
180.1
168
*
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
86.9
176.4
195
27
AA1AD
NOMESCO Finland
CT of head and brain
6.6
173.6
589
1589
AAG00
NOMESCO Finland
Stereotactic intracranial biopsy
1980.4
173.5
164
*
C71.13
ICD-10 Finland
Malignant tumor of frontal lobe grade IV glioma
+∞
163.6
153
*
YX8VG
NOMESCO Finland
Stereotactic MRI exmaination with high intensity magnet for dose design of radiotherapy
603.0
162.2
157
*
C71.1
ICD-10 Finland
Malignant neoplasm: Frontal lobe
+∞
151.5
142
*
Z51.5
ICD-10 Finland
Palliative care
13.4
151.3
281
272
N03AF02
ATC
oxcarbazepine; oral
19.6
146.9
230
145
YX8BD
NOMESCO Finland
Stereotactic extensive CT examination for dose design of radiotherapy
227.7
138.2
140
7
C71.2
ICD-10 Finland
Malignant neoplasm: Temporal lobe
+∞
137.3
129
*
C71.12
ICD-10 Finland
Malignant tumor of frontal lobe grade III glioma
+∞
135.1
127
*
XX3DW
NOMESCO Finland
Time consuming IT work
8.4
135.1
333
535
9440/3-C71.9
ICD-O-3
Glioblastoma, NOS, of brain, NOS
+∞
134.0
126
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
18.4
131.9
211
139
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
6.1
128.2
420
997
A04AA01
ATC
ondansetron; systemic, rectal
10.3
126.2
268
330
R56.8
ICD-10 Finland
Other and unspecified convulsions
11.5
117.9
234
251
ZXC40
NOMESCO Finland
Use of ultrasound
77.0
115.4
130
19
N03AX18
ATC
lacosamide; systemic
67.7
115.0
132
22
D43.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Central nervous system, unspecified
317.6
114.3
114
*
C71.30
ICD-10 Finland
Malignant tumor in parietal lobe without histology
581.0
108.7
106
*
C71.21
ICD-10 Finland
Malignant tumor of temporal lobe grade II glioma
1141.7
108.2
104
*
9440/3-C71.2
ICD-O-3
Glioblastoma, NOS, of temporal lobe
+∞
108.1
102
*
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
7.8
106.1
268
431
XA800
NOMESCO Finland
Neuropsychological investigation
11.6
100.3
196
200
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
44.5
97.1
120
30
C71.99
ICD-10 Finland
Malignant tumor in unspecified localization in the brain other or unspecified histology
216.5
97.0
99
5
C71.22
ICD-10 Finland
Malignant tumor of temporal lobe grade III glioma
+∞
96.2
91
*
C71.33
ICD-10 Finland
Malignant tumor of parietal lobe grade IV glioma
962.7
92.2
89
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
9.6
91.0
197
242
9440/3-C71.1
ICD-O-3
Glioblastoma, NOS, of frontal lobe
+∞
90.9
86
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
12.4
89.3
168
157
WX882
NOMESCO Finland
High dependency care
13.8
89.2
159
132
ZX050
NOMESCO Finland
Stereotactic radiotherapy
53.0
88.7
106
22
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
17.1
87.3
142
94
D43.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, unspecified
192.8
86.5
89
5
G40.9
ICD-10 Finland
Epilepsy, unspecified
12.0
86.0
164
157
9680/3-C71.9
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of brain, NOS
+∞
76.9
73
*
AA1BD
NOMESCO Finland
Extensive CT of head and brain
13.3
76.8
139
118
N74
ICPC
Malignant neoplasm nervous system
788.7
76.2
74
*
C71.29
ICD-10 Finland
Malignant tumor in temporal lobe other or unspecified histology
754.5
73.0
71
*
ZX095
NOMESCO Finland
Combined chemoradiotherapy
61.1
72.9
85
15
A02BC02
ATC
pantoprazole; systemic
3.3
72.9
841
5251
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
32.6
72.6
96
32
N03AB02
ATC
phenytoin; systemic
29.7
72.3
98
36
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
6.8
70.9
193
332
C71.00
ICD-10 Finland
Malignant tumor of the cerebrum except lobes and ventricles without histology
731.8
70.9
69
*
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
26.4
69.4
97
40
C71.19
ICD-10 Finland
Malignant tumor of frontal lobe other or unspecified histology
+∞
68.4
65
*
C71.3
ICD-10 Finland
Malignant neoplasm: Parietal lobe
+∞
65.2
62
*
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
3.1
63.6
505
2354
ZXE20
NOMESCO Finland
More than three and less than five hours
4.1
62.9
283
847
9380/3-C71.9
ICD-O-3
Glioma, malignant of brain, NOS
+∞
61.0
58
*
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
31.0
60.7
81
28
AAA10
NOMESCO Finland
Biopsy through craniotomy
166.5
60.6
63
*
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
14.6
59.9
103
77
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
17.5
59.4
95
59
YA1VG
NOMESCO Finland
MRI examination of head and neck with high intesity magnet for dose design of radiotherapy
54.6
56.5
67
13
ZXM40
NOMESCO Finland
Use of fluorescent substance
289.7
54.7
55
*
G40.10
ICD-10 Finland
Simple partial seizures
27.6
54.5
75
29
D43.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, infratentorial
101.8
53.3
58
6
C71.83
ICD-10 Finland
Overall malignant tumor of the brain grade IV glioma
+∞
52.5
50
*
ZX070
NOMESCO Finland
Intensity modified radiotherapy
14.3
51.5
89
67
9400/3-C71.9
ICD-O-3
Astrocytoma, NOS, of brain, NOS
+∞
50.4
48
*
C71.31
ICD-10 Finland
Malignant tumor of the parietal lobe grand II glioma
+∞
50.4
48
*
9440/3-C71.3
ICD-O-3
Glioblastoma, NOS, of parietal lobe
+∞
49.3
47
*
9400/3-C71.1
ICD-O-3
Astrocytoma, NOS, of frontal lobe
+∞
48.3
46
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
3.1
47.7
321
1284
WX402
NOMESCO Finland
General anaesthesia
3.3
47.4
280
1020
C71.9
ICD-10 Finland
Malignant neoplasm: Brain, unspecified
+∞
47.2
45
*
8000/3-C71.9
ICD-O-3
Neoplasm, malignant of brain, NOS
+∞
46.1
44
*
N05BA09
ATC
clobazam; oral
36.5
46.1
59
17
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
16.5
45.0
73
47
N02AA05
ATC
oxycodone; systemic
3.4
44.2
250
876
C71.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of brain
+∞
44.0
42
*
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
19.4
43.2
66
36
R90.8
ICD-10 Finland
Other abnormal findings on diagnostic imaging of central nervous system
20.2
43.1
65
34
9450/3-C71.1
ICD-O-3
Oligodendroglioma, NOS, of frontal lobe
+∞
43.0
41
*
N03AF01
ATC
carbamazepine; oral, rectal
5.6
42.8
133
264
N05CD08
ATC
midazolam; nasal, systemic
10.6
42.8
85
86
N03AG01
ATC
valproic acid; systemic, rectal
5.0
42.3
145
322
C71.32
ICD-10 Finland
Malignant tumor of parietal lobe grade III glioma
+∞
41.9
40
*
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
19.5
41.4
63
34
WX872
NOMESCO Finland
Intensive care
5.8
41.0
123
234
H53.4
ICD-10 Finland
Visual field defects
9.5
39.5
83
93
WZC30
NOMESCO Finland
Teaching
3.3
38.8
222
777
C71.40
ICD-10 Finland
Malignant tumor of the occipital lobe without histology
+∞
37.7
36
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.5
36.7
372
1856
WF004
NOMESCO Finland
Palliative radiotherapy
11.2
36.5
70
66
R90.0
ICD-10 Finland
Intracranial space-occupying lesion
368.4
36.2
36
*
N76
ICPC
Neoplasm nervous system unspecified
100.9
35.9
39
*
A28
ICPC
Limited function/disability NOS
3.1
35.9
227
851
C71.80
ICD-10 Finland
Overall malignant tumor of the brain without histology
357.7
35.1
35
*
ZX090
NOMESCO Finland
Other technic of radiotherapy
8.6
35.0
78
97
H02AB09
ATC
hydrocortisone; systemic
7.8
34.7
82
112
WF029
NOMESCO Finland
Radiotherapy of local residive tumor
35.1
34.3
44
13
183
Kela drug reimbursment
Lamotrigin and topiramate
21.7
34.2
50
24
C71.93
ICD-10 Finland
Malignant tumor in an unspecified localization in the brain grade IV glioma
+∞
33.5
32
*
ZXE30
NOMESCO Finland
More than five and less than seven hours
4.9
33.1
113
248
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.9
33.0
226
890
G40.19
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
23.3
32.9
47
21
C71.39
ICD-10 Finland
Malignant tumor of parietal lobe other or unspecified histology
+∞
32.4
31
*
C71.01
ICD-10 Finland
Malignant tumor of cerebellum except lobes and ventricles grade II glioma
325.7
32.0
32
*
C71.43
ICD-10 Finland
Malignant tumor of the occipital lobe grade IV glioma
+∞
31.4
30
*
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
4.7
30.6
110
255
WC105
NOMESCO Finland
Simple cytostatic therapy of local tumor recidive
31.8
30.5
40
13
R4150
NOMESCO Finland
Neuropsychological rehabilitation
21.7
30.2
44
21
TAB00
NOMESCO Finland
Lumbar puncture
5.0
30.0
101
218
9450/3-C71.9
ICD-O-3
Oligodendroglioma, NOS, of brain, NOS
+∞
29.3
28
*
C85.9
ICD-10 Finland
Non-Hodgkin lymphoma, unspecified
20.3
28.9
43
22
C83.3
ICD-10 Finland
Diffuse large B-cell lymphoma
34.7
28.8
37
11
TPH04
NOMESCO Finland
Cathetrisation of vein
2.4
28.4
284
1378
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
8.5
27.9
62
77
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
8.6
27.8
61
74
C79.30
ICD-10 Finland
Secondary malignant tumor of the cerebrum
14.7
26.3
44
31
G40.11
ICD-10 Finland
Simple partial epileptic seizure that develops into a complex partial seizure
74.4
25.9
29
*
N05CF01
ATC
zopiclone; oral
2.1
25.4
393
2309
G40.21
ICD-10 Finland
Partial epileptic seizure with cloudiness and automatism
51.2
25.3
30
6
G41.9
ICD-10 Finland
Status epilepticus, unspecified
26.9
25.0
34
13
A98
ICPC
Health maint/preventive medicine
0.5
24.6
836
9770
WX704
NOMESCO Finland
Intubation
3.5
24.5
120
367
AA5FG
NOMESCO Finland
Functional MRI examination of brain with high intensity magnet
+∞
24.0
23
*
9401/3-C71.1
ICD-O-3
Astrocytoma, anaplastic, NOS, of frontal lobe
+∞
24.0
23
*
C71.03
ICD-10 Finland
Malignant tumor of cerebellum except lobes and ventricles grade IV glioma
+∞
24.0
23
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.5
23.9
214
970
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
4.4
23.8
90
219
ZSA00
NOMESCO Finland
Procedure related to previous procedure classified in chapter A
20.6
23.1
34
17
R4110
NOMESCO Finland
Physiotherapy
2.1
22.7
326
1840
WX110
NOMESCO Finland
Local anesthesy
1.9
22.5
774
6010
A79
ICPC
Malignancy NOS
9.5
22.4
46
50
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
11.8
22.3
41
36
9400/3-C71.2
ICD-O-3
Astrocytoma, NOS, of temporal lobe
+∞
21.9
21
*
TPH07
NOMESCO Finland
Cathetrisation of artery
2.8
21.0
148
582
C71.89
ICD-10 Finland
Overall malignant tumor of the brain other or unspecified histology
+∞
20.9
20
*
9451/3-C71.1
ICD-O-3
Oligodendroglioma, anaplastic, NOS, of frontal lobe
+∞
20.9
20
*
C71.82
ICD-10 Finland
Overall malignant tumor of the brain grade III glioma
+∞
20.9
20
*
R4120
NOMESCO Finland
Occupational therapy
3.3
20.4
110
362
Z2445
NOMESCO Finland
Psychologist
4.2
20.3
79
198
C71
ICD-10 Finland
Malignant neoplasm of brain
+∞
19.8
19
*
9440/3-C71.0
ICD-O-3
Glioblastoma, NOS, of cerebrum
+∞
19.8
19
*
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
8.9
19.7
42
49
WW300
NOMESCO Finland
Transfer of autologic stem cells
19.8
19.6
29
15
JN4BD
NOMESCO Finland
Extensive body CT
2.6
19.4
151
627
L03AA02
ATC
filgrastim; parenteral
5.1
19.2
61
124
G91.1
ICD-10 Finland
Obstructive hydrocephalus
18.6
19.2
29
16
ZXE10
NOMESCO Finland
More than one and less than three hours
1.8
18.9
412
2683
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
8.5
18.8
41
50
C71.4
ICD-10 Finland
Malignant neoplasm: Occipital lobe
+∞
18.8
18
*
9401/3-C71.9
ICD-O-3
Astrocytoma, anaplastic, NOS, of brain, NOS
+∞
18.8
18
*
C71.60
ICD-10 Finland
Malignant tumor of cerebellum without histology
+∞
18.8
18
*
R4130
NOMESCO Finland
Speech therapy
6.4
18.7
49
79
R47.0
ICD-10 Finland
Dysphasia and aphasia
11.6
18.6
34
30
ZXD10
NOMESCO Finland
Scheduled procedure
1.8
18.5
429
2844
XF400
NOMESCO Finland
ECG with 12 standard connections
2.2
18.4
210
1061
XX9BW
NOMESCO Finland
Submitting image material and/or investigation material to authority or other institution
9.5
18.2
37
40
C71.0
ICD-10 Finland
Malignant neoplasm: Cerebrum, except lobes and ventricles
+∞
17.7
17
*
9401/3-C71.2
ICD-O-3
Astrocytoma, anaplastic, NOS, of temporal lobe
+∞
17.7
17
*
C71.70
ICD-10 Finland
Malignant tumor of the brainstem without histology
96.5
17.6
19
*
D33.00
ICD-10 Finland
Medial pilosytic astrocytoma of the cerebrum
64.3
16.8
19
*
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.7
16.6
123
497
PA7ST
NOMESCO Finland
Extensive medical infusion to cerebral artery
91.4
16.6
18
*
G40
ICD-10 Finland
Epilepsy
11.8
16.6
30
26
C71.65
ICD-10 Finland
Malignant tumor of the cerebellum primary neuroectodermal tumor
172.4
16.5
17
*
YX8AD
NOMESCO Finland
Stereotactic CT examination for dose design of radiotherapy
40.7
16.4
20
5
N03AX23
ATC
brivaracetam; systemic
40.7
16.4
20
5
WX725
NOMESCO Finland
Noninvasive ventilation
3.6
16.1
74
216
G40.2
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
13.8
16.0
27
20
C71.02
ICD-10 Finland
Malignant tumor of the cerebrum except lobes and ventricles grade III glioma
+∞
15.7
15
*
C71.81
ICD-10 Finland
Overall malignant tumor of the brain grade II glioma
+∞
15.7
15
*
9382/3-C71.1
ICD-O-3
Oligoastrocytoma, NOS, of frontal lobe
+∞
15.7
15
*
C71.50
ICD-10 Finland
Malignant tumor of cerebral ventricle without histology
+∞
15.7
15
*
D69.5
ICD-10 Finland
Secondary thrombocytopenia
26.7
15.6
21
8
C71.91
ICD-10 Finland
Malignant tumor in unspecified location in the brain grade II glioma
162.1
15.5
16
*
N05BA04
ATC
oxazepam; oral
1.9
15.1
278
1684
N03AX22
ATC
perampanel; oral
45.6
15.1
18
*
YX9BD
NOMESCO Finland
Other extensive CT eamination for dose design of radiotherapy
10.2
15.0
29
29
PA4AC
NOMESCO Finland
Vertebralis angiography with X-ray
32.2
14.8
19
6
C71.09
ICD-10 Finland
Malignant tumor of the cerebrum except lobes and ventricles other or unspecified histology
+∞
14.6
14
*
9440/3-C71.8
ICD-O-3
Glioblastoma, NOS, of overlapping lesion of brain
+∞
14.6
14
*
XA400
NOMESCO Finland
EEG
14.4
14.6
24
17
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
3.6
14.4
65
187
AWB00
NOMESCO Finland
Reoperation for superficial infection in surgery of the nervous system
27.6
14.3
19
7
PA3AC
NOMESCO Finland
Carotis angiography with X-ray
19.4
14.3
21
11
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
7.1
14.2
34
49
G40.89
ICD-10 Finland
Other epilepsy
14.6
14.1
23
16
AA5BD
NOMESCO Finland
CT of cerebral ischaemia
6.0
14.0
38
65
Z2446
NOMESCO Finland
Social worker
2.7
13.9
97
378
WW500
NOMESCO Finland
Blood transfusion
3.4
13.7
66
201
2151
FHL
Resection, big brain
141.6
13.5
14
*
PA7RT
NOMESCO Finland
Medical infusion to cerebral artery
141.6
13.5
14
*
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
2.3
13.4
126
579
G93.6
ICD-10 Finland
Cerebral oedema
50.6
12.9
15
*
WX892
NOMESCO Finland
Monitored bed care
2.6
12.8
100
414
9470/3-C71.6
ICD-O-3
Medulloblastoma, NOS, of cerebellum, NOS
+∞
12.5
12
*
C71.51
ICD-10 Finland
Malignant tumor of cerebral ventricle ependymoma
+∞
12.5
12
*
D33.08
ICD-10 Finland
Another benign tumor of the cerebral ventricle
+∞
12.5
12
*
C71.59
ICD-10 Finland
Malignant tumor of cerebral ventricle other or unspecified histology
+∞
12.5
12
*
9440/3-C71.4
ICD-O-3
Glioblastoma, NOS, of occipital lobe
+∞
12.5
12
*
N28
ICPC
Limited function/disability (N)
6.1
12.5
33
55
C71.69
ICD-10 Finland
Malignant tumor of the cerebellum other or unspecified histology
131.3
12.5
13
*
WX730
NOMESCO Finland
Conventional respirator
5.8
12.3
34
60
G41.2
ICD-10 Finland
Complex partial status epilepticus
38.0
12.2
15
*
AA5DR
NOMESCO Finland
Brain metabolism PET with CT
38.0
12.2
15
*
D70.82
ICD-10 Finland
Drug-induced neutropenia
5.9
12.1
33
57
Z73.3
ICD-10 Finland
Stress, not elsewhere classified
7.1
12.1
29
42
R51.80
ICD-10 Finland
Headache
2.0
12.0
162
870
PA2BD
NOMESCO Finland
Extensive CT angiography of brain
5.2
11.9
36
71
R41.0
ICD-10 Finland
Disorientation, unspecified
3.9
11.6
47
124
AA5JS
NOMESCO Finland
Extensive PET-MRI of brain metabolism
+∞
11.5
11
*
C71.74
ICD-10 Finland
Malignant tumor of the brainstem ependyoma
+∞
11.5
11
*
C71.6
ICD-10 Finland
Malignant neoplasm: Cerebellum
121.1
11.4
12
*
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
8.0
11.4
25
32
B01AB10
ATC
tinzaparin; parenteral
2.5
11.4
88
364
CS494
NOMESCO Finland
Other visual field testing
4.9
11.4
36
75
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
4.1
11.3
43
108
N18
ICPC
Paralysis/weakness
5.4
11.2
33
63
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
5.8
11.2
31
55
ZXM20
NOMESCO Finland
Intraoperative use of computerised tomography
8.1
11.1
24
30
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
9.3
11.0
22
24
TAA40
NOMESCO Finland
Cathetrisation of cerebrospinal fluid through skin
18.0
10.7
16
9
ZXY02
NOMESCO Finland
Neuropsychologist
13.0
10.7
18
14
G41.0
ICD-10 Finland
Grand mal status epilepticus
60.6
10.6
12
*
23810
ICD-8 Finland
Neoplasm of unspecified nature of eye, brain and other parts of nervous system, Brain
60.6
10.6
12
*
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.9
10.6
171
980
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
2.6
10.6
75
297
I61.9
ICD-10 Finland
Intracerebral haemorrhage, unspecified
5.5
10.5
30
56
9450/3-C71.3
ICD-O-3
Oligodendroglioma, NOS, of parietal lobe
+∞
10.4
10
*
9450/3-C71.2
ICD-O-3
Oligodendroglioma, NOS, of temporal lobe
+∞
10.4
10
*
9591/3-C71.9
ICD-O-3
Malignant lymphoma, non-Hodgkin, NOS, of brain, NOS
+∞
10.4
10
*
C71.7
ICD-10 Finland
Malignant neoplasm: Brain stem
+∞
10.4
10
*
9382/3-C71.9
ICD-O-3
Oligoastrocytoma, NOS, of brain, NOS
+∞
10.4
10
*
SPAT1245
SPAT
Provision of support and information to patient’s family members
3.1
10.1
55
185
L28
ICPC
Limited function/disability (L)
1.9
10.1
156
877
U07.2
ICD-10 Finland
COVID-19, virus not identified
0.4
10.1
48
1089
NA7BG
NOMESCO Finland
Spine and spinal cord MRI examination with high intensity magnet
9.2
10.0
20
22
Z51.0
ICD-10 Finland
Radiotherapy session
6.8
9.9
24
36
WW409
NOMESCO Finland
Other aferesis
16.9
9.9
15
9
ZXH01
NOMESCO Finland
Procedure performed within operation theatre
16.9
9.9
15
9
N03AX11
ATC
topiramate; oral
3.9
9.9
39
102
XX1ZW
NOMESCO Finland
Very extensive written report from radiologist
12.3
9.9
17
14
101
Kela drug reimbursment
Anterior pituitary hypofunction
8.2
9.8
21
26
TPX10
NOMESCO Finland
Implantation of vascular injection port
3.5
9.8
44
128
SAA01
NOMESCO Finland
Simple examination of mouth
0.7
9.7
502
6147
C01DA14
ATC
isosorbide mononitrate; oral
0.4
9.7
40
959
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
2.7
9.7
65
249
SPAT1153
SPAT
Removal of sutures
1.6
9.7
318
2239
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
3.7
9.6
40
110
F80.1
ICD-10 Finland
Expressive language disorder
9.2
9.5
19
21
G81.9
ICD-10 Finland
Hemiplegia, unspecified
7.2
9.5
22
31
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
3.9
9.5
37
96
22500
ICD-8 Finland
Benign neoplasm of brain and other parts of nervous system, Brain
100.8
9.4
10
*
C71.92
ICD-10 Finland
Malignant tumor in an unspecified localization in the brain grade III glioma
+∞
9.4
9
*
AA003
NOMESCO Finland
Adjuvant radiotherapy of brain
+∞
9.4
9
*
C71.61
ICD-10 Finland
Malignant tumor of cerebellum grade II glioma
+∞
9.4
9
*
D33.05
ICD-10 Finland
Other lateral benign tumor in temporal lobe
+∞
9.4
9
*
Z25.8
ICD-10 Finland
Need for immunization against other specified single viral diseases
0.3
9.4
26
738
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
2.7
9.3
62
236
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
9.3
433
3302
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
2.4
9.2
76
329
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
7.1
9.0
21
30
B01AB05
ATC
enoxaparin; parenteral
1.6
9.0
294
2062
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
5.1
9.0
27
54
ZXA00
NOMESCO Finland
Right side
1.6
8.9
269
1847
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
4.3
8.7
31
74
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
0.6
8.6
240
3331
M75.1
ICD-10 Finland
Rotator cuff syndrome
0.5
8.6
88
1555
N88
ICPC
Epilepsy
11.7
8.6
15
13
N80
ICPC
Head injury other
5.0
8.5
26
53
N19
ICPC
Speech disorder
5.4
8.5
24
45
RS221
NOMESCO Finland
NA
4.7
8.4
27
58
C71.42
ICD-10 Finland
Malignant tumor of the occipital lobe grade III glioma
90.7
8.4
9
*
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
2.8
8.4
51
186
2159
FHL
Other measure in this category
+∞
8.3
8
*
C71.49
ICD-10 Finland
Malignant tumor in occipital lobe other or unspecified histology
+∞
8.3
8
*
9445/3-C71.9
ICD-O-3
Glioblastoma, IDH-mutant of brain, NOS
+∞
8.3
8
*
9400/3-C71.0
ICD-O-3
Astrocytoma, NOS, of cerebrum
+∞
8.3
8
*
9391/3-C71.7
ICD-O-3
Ependymoma, NOS, of brain stem
+∞
8.3
8
*
AA5FK
NOMESCO Finland
Functional assessment (fMRI) of brain
+∞
8.3
8
*
I61.0
ICD-10 Finland
Intracerebral haemorrhage in hemisphere, subcortical
5.3
8.3
24
46
ZXE17
NOMESCO Finland
Procedure duration 150 to 179 minutes
5.3
8.3
24
46
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.0
8.3
114
613
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
0.4
8.3
33
801
R03AC02
ATC
salbutamol; inhalant
0.7
8.3
321
4188
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
0.5
8.3
82
1461
M25.5
ICD-10 Finland
Pain in joint
0.6
8.2
120
1930
ZXD05
NOMESCO Finland
Urgent procedure
1.5
8.2
323
2359
AA7AA
NOMESCO Finland
Liquor cerebri shunt X-ray examinatin without contrast
14.6
8.2
13
9
N02BE01
ATC
paracetamol; systemic, rectal
1.5
8.1
887
7959
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
5.1
8.0
24
48
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
3.3
8.0
38
117
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
0.5
8.0
77
1387
H53.2
ICD-10 Finland
Diplopia
3.2
7.7
39
126
N03AF04
ATC
eslicarbazepine; oral
45.3
7.7
9
*
A06AD11
ATC
lactulose; oral
1.8
7.7
145
871
ZXD35
NOMESCO Finland
Usual procedure
2.9
7.7
45
160
C10AX09
ATC
ezetimibe; oral
0.3
7.6
22
614
AAF25
NOMESCO Finland
Removal of shunt of ventricle of brain
18.5
7.6
11
6
G83.9
ICD-10 Finland
Paralytic syndrome, unspecified
18.5
7.6
11
6
D32.02
ICD-10 Finland
Benign tumor of the meninges at the base of the brain
8.1
7.6
16
20
C85.1
ICD-10 Finland
B-cell lymphoma, unspecified
11.9
7.6
13
11
2396A
ICD-9 Finland
Neoplasm of unspecified nature, Brain
80.6
7.4
8
*
C71.79
ICD-10 Finland
Malignant tumor of the brainstem other or unspecified histology
80.6
7.4
8
*
1911X
ICD-9 Finland
Malignant neoplasm of brain, Frontal lobe[AIVOJEN OTSALOHKON SYÖPÄ,EI HISTOLOGISTA VAHVISTUST]
80.6
7.4
8
*
R93.0
ICD-10 Finland
Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified
13.5
7.4
12
9
I25.1
ICD-10 Finland
Atherosclerotic heart disease
0.5
7.3
83
1430
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
3.6
7.3
31
88
8000/3-C71.2
ICD-O-3
Neoplasm, malignant of temporal lobe
+∞
7.3
7
*
8000/3-C71.1
ICD-O-3
Neoplasm, malignant of frontal lobe
+∞
7.3
7
*
9400/3-C71.3
ICD-O-3
Astrocytoma, NOS, of parietal lobe
+∞
7.3
7
*
D33.2
ICD-10 Finland
Benign neoplasm: Brain, unspecified
+∞
7.3
7
*
C71.73
ICD-10 Finland
Malignant tumor of the brain stem grade IV glioma
+∞
7.3
7
*
D43
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour of brain and central nervous system
+∞
7.3
7
*
19107
ICD-8 Finland
Malignant neoplasm of brain, Cerebelli
+∞
7.3
7
*
TPX15
NOMESCO Finland
Removal of vascular injection port
9.4
7.3
14
15
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
5.2
7.3
21
41
H01AC01
ATC
somatropin; parenteral
15.9
7.2
11
7
2152
FHL
Extraction, big brain
30.2
7.2
9
*
G40.1
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
12.1
7.1
12
10
SDA03
NOMESCO Finland
Demanding parodonthologic therapy
0.7
7.0
194
2720
N03AX09
ATC
lamotrigine; oral
2.5
7.0
52
211
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
5.2
6.9
20
39
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
2.6
6.9
48
189
M54.4
ICD-10 Finland
Lumbago with sciatica
0.5
6.8
51
991
G40.39
ICD-10 Finland
Other or unspecified generalized epileptic syndromes with atonic, clonic, myoclonic or tonic-clonic seizures
8.3
6.8
14
17
R1260
NOMESCO Finland
Evaluation of communicative skills
4.2
6.8
24
58
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
2.0
6.8
83
428
Z02.4
ICD-10 Finland
Examination for driving licence
0.6
6.8
91
1501
R83
ICPC
Respiratory infection other
0.6
6.8
104
1661
D42.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Cerebral meninges
40.3
6.8
8
*
AWC00
NOMESCO Finland
Reoperation of nervous system because of deep wound infection in the nervous system
16.8
6.7
10
6
102
Kela drug reimbursment
Diabetes insipidus
16.8
6.7
10
6
ZXA05
NOMESCO Finland
Left side
1.5
6.7
241
1717
YNB10
NOMESCO Finland
Collection of stem cells for transplant
22.6
6.7
9
*
9530/0-C70.0
ICD-O-3
Meningioma, NOS, of cerebral meninges
7.9
6.6
14
18
PA7CD
NOMESCO Finland
CT angiography of neck and brain, extensive
4.6
6.6
21
46
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.2
6.6
66
314
UJF32
NOMESCO Finland
Coloscopy
0.6
6.6
114
1766
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.6
6.6
161
1043
SPAT1325
SPAT
Vaccination
0.7
6.6
172
2436
D32.9
ICD-10 Finland
Benign neoplasm: Meninges, unspecified
8.7
6.6
13
15
K90
ICPC
Stroke/cerebrovascular accident
3.1
6.5
33
108
L03
ICPC
Low back symptom/complaint
0.6
6.5
96
1545
I48
ICD-10 Finland
Atrial fibrillation and flutter
0.6
6.5
89
1458
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
4.5
6.5
21
47
SPAT1229
SPAT
Assessment of need for aid
2.0
6.4
80
415
N75
ICPC
Benign neoplasm nervous system
70.2
6.4
7
*
ZX000
NOMESCO Finland
Simple adjustment of radiotherapy with simulator or with therapeutic device - isocentric therapy
70.2
6.4
7
*
AAF30
NOMESCO Finland
Implantation of intraventricular injection device
70.2
6.4
7
*
C72.9
ICD-10 Finland
Malignant neoplasm: Central nervous system, unspecified
70.2
6.4
7
*
C71.63
ICD-10 Finland
Malignant tumor of cerebellum grade IV glioma
70.2
6.4
7
*
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
0.4
6.4
31
701
R03DC03
ATC
montelukast; oral
0.5
6.4
51
974
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.0
6.4
82
432
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.7
6.4
138
865
A07AA02
ATC
nystatin; oral
2.2
6.3
64
305
H47.1
ICD-10 Finland
Papilloedema, unspecified
8.2
6.3
13
16
N29
ICPC
Neurological sympt/complt other
3.6
6.3
26
73
C72.3
ICD-10 Finland
Malignant neoplasm: Optic nerve
+∞
6.3
6
*
9380/3-C71.2
ICD-O-3
Glioma, malignant of temporal lobe
+∞
6.3
6
*
9382/3-C71.2
ICD-O-3
Oligoastrocytoma, NOS, of temporal lobe
+∞
6.3
6
*
C71.66
ICD-10 Finland
Malignant tumor of the cerebellum medullobastoma
+∞
6.3
6
*
9401/3-C71.3
ICD-O-3
Astrocytoma, anaplastic, NOS, of parietal lobe
+∞
6.3
6
*
1BC01
NOMESCO Finland
NA
+∞
6.3
6
*
C71.41
ICD-10 Finland
Malignant tumor of occipital lobe grade II glioma
+∞
6.3
6
*
9380/3-C71.1
ICD-O-3
Glioma, malignant of frontal lobe
+∞
6.3
6
*
1911A
ICD-9 Finland
Malignant neoplasm of brain, Frontal lobe[AIVOJEN OTSALOHKON SYÖPÄ,ASTROCYTOMA (GR I-II)]
+∞
6.3
6
*
9391/3-C71.5
ICD-O-3
Ependymoma, NOS, of ventricle, NOS
+∞
6.3
6
*
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
4.3
6.2
21
49
ZX131
NOMESCO Finland
Intrathecal
26.8
6.2
8
*
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
0.5
6.2
58
1053
R47.8
ICD-10 Finland
Other and unspecified speech disturbances
7.1
6.2
14
20
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
2.5
6.2
45
184
M17
ICD-10 Finland
Gonarthrosis [arthrosis of knee]
0.4
6.2
19
513
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
1.9
6.2
86
467
Z3226
NOMESCO Finland
Physiotherapist
1.6
6.1
186
1272
N05BA01
ATC
diazepam; systemic, rectal
1.7
6.1
129
800
R07.4
ICD-10 Finland
Chest pain, unspecified
0.6
6.0
126
1872
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: C3_BRAIN – Malignant neoplasm of brain
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).