Other demyelinating diseases of the central nervous system

G6_OTHDEMYEL

Please describe the specific diseases included, such as NMOSD, MOGAD, or undiagnosed demyelinating diseases, etc., much appreciated!

Suggest a new description

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 G37
  • Hospital discharge: ICD-9 341[1-9]
  • Hospital discharge: ICD-8 3410[2-9]
  • Cause of death: ICD-10 G37
  • Cause of death: ICD-9 341[1-9]
  • Cause of death: ICD-8 3410[2-9]

2 out of 7 registries used, show all original rules.

1520

4. Check minimum number of events

None

1520

5. Include endpoints

None

1520

6. Filter based on genotype QC (FinnGen only)

1462

Control definitions (FinnGen only)

Control exclude
G6_DEMYEL

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
G35-G37
Name in latin
Alii morbi demyelinantes systematis nervosi centralis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 8543 5445 3043
Only index persons 7717 5057 2660
Unadjusted period prevalence (%)
Whole population 0.13 0.16 0.09
Only index persons 0.16 0.19 0.10
Median age at first event (years)
Whole population 39.82 38.63 41.86
Only index persons 39.14 38.08 41.15

-FinnGen-

Key figures

All Female Male
Number of individuals 1462 1064 398
Unadjusted period prevalence (%) 0.32 0.38 0.18
Median age at first event (years) 39.86 38.47 43.57

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1520
Matched controls
15200
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
39.1
322.8
201
59
N04BB01
ATC
amantadine; oral
43.3
314.0
190
50
N86
ICPC
Multiple sclerosis
2006.8
307.7
313
*
H46
ICD-10 Finland
Optic neuritis
147.7
307.7
278
23
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
23.9
307.7
770
627
G37.9
ICD-10 Finland
Demyelinating disease of central nervous system, unspecified
+∞
307.7
1190
*
TAB00
NOMESCO Finland
Lumbar puncture
30.8
307.7
583
301
109
Kela drug reimbursment
Multiple sclerosis
+∞
307.7
765
*
303
Kela drug reimbursment
Dimethyl fumarate, interferon beta, glatiramer acetate and teriflunomid (Multiple sclerosis)
+∞
307.7
654
*
G35
ICD-10 Finland
Multiple sclerosis
8132.6
307.7
1015
*
L03AB07
ATC
interferon beta-1a; parenteral
+∞
307.7
310
*
157
Kela drug reimbursment
Dimethyl fumarate, glatiramer acetate, interferon beta and teriflunomid (Multiple sclerosis)
+∞
307.7
653
*
L03AX13
ATC
glatiramer acetate; parenteral
+∞
287.9
267
*
M03BX01
ATC
baclofen; systemic
21.6
249.7
192
101
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
7.5
243.9
421
737
L04AX07
ATC
dimethyl fumarate; oral
+∞
243.4
227
*
R20.2
ICD-10 Finland
Paraesthesia of skin
7.8
234.0
382
628
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
17.0
205.6
177
117
L04AA31
ATC
[U] teriflunomide
+∞
204.9
192
*
164
Kela drug reimbursment
Fingolimod
+∞
203.8
191
*
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
18.8
198.7
162
96
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
27.0
185.8
129
52
353
Kela drug reimbursment
Cladribine and fingolimod
+∞
185.3
174
*
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
7.5
162.4
258
404
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
11.0
161.2
181
184
XA800
NOMESCO Finland
Neuropsychological investigation
8.1
141.5
205
288
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
11.9
140.9
148
136
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
5.6
138.2
304
652
L04AA27
ATC
[U] fingolimod
+∞
132.2
125
*
L03AB08
ATC
interferon beta-1b; parenteral
+∞
130.1
123
*
N07XX09
ATC
[U] dimethyl fumarate
+∞
129.0
122
*
XKD06
NOMESCO Finland
Physiologic investigation of micturition
12.2
128.6
133
119
XCK00
NOMESCO Finland
Perimetry
7.7
128.0
192
280
NA7BG
NOMESCO Finland
Spine and spinal cord MRI examination with high intensity magnet
29.8
123.0
82
29
G37.3
ICD-10 Finland
Acute transverse myelitis in demyelinating disease of central nervous system
+∞
120.4
114
*
G04BD12
ATC
mirabegron; oral
5.2
112.1
259
575
G04BD09
ATC
trospium; oral
16.2
111.0
96
63
N06BA07
ATC
modafinil; oral
37.7
104.6
65
18
2AB04, ,
NOMESCO Finland
184.0
99.6
103
6
NA2CG
NOMESCO Finland
Thoracal spine extensive MRI examination with high intensity magnet
20.5
98.8
76
39
G97.0
ICD-10 Finland
Cerebrospinal fluid leak from spinal puncture
11.7
97.1
102
93
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.6
97.1
418
1463
R90.8
ICD-10 Finland
Other abnormal findings on diagnostic imaging of central nervous system
15.5
96.2
85
58
ZX120
NOMESCO Finland
Intravenous
4.4
88.3
250
649
L04AK02
ATC
teriflunomide; oral
+∞
87.3
83
*
H53.2
ICD-10 Finland
Diplopia
7.4
84.9
128
186
G36.9
ICD-10 Finland
Acute disseminated demyelination, unspecified
+∞
84.1
80
*
L03AB13
ATC
peginterferon beta-1a; parenteral
+∞
77.8
74
*
XKD00
NOMESCO Finland
Uroflowmetry
4.2
76.1
224
596
N31.9
ICD-10 Finland
Neuromuscular dysfunction of bladder, unspecified
21.5
74.5
56
27
XKC03
NOMESCO Finland
Water cystometry
7.9
72.7
103
139
L04AG12
ATC
ofatumumab; parenteral
+∞
71.4
68
*
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
4.3
71.0
204
532
G37.2
ICD-10 Finland
Central pontine myelinolysis
+∞
67.2
64
*
N03AX12
ATC
[U] gabapentin; oral
3.1
67.2
357
1388
UKC02
NOMESCO Finland
Cystoscopy
3.6
66.7
255
811
TKC22
NOMESCO Finland
Catheterisation instruction
11.1
64.0
69
65
3419X
ICD-9 Finland
Other demyelinating diseases of central nervous system, Demyelinating disease of central nervous system, unspecified
+∞
62.9
60
*
N03AE01
ATC
clonazepam; systemic
4.6
62.7
162
388
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
16.0
62.5
54
35
TAB22
NOMESCO Finland
Stoppin epidural fluid escape with coagulated blood
9.5
60.8
73
80
F02.89*G35
ICD-10 Finland
Dementia in multiple sclerosis
+∞
59.8
57
*
G37.8
ICD-10 Finland
Other specified demyelinating diseases of central nervous system
+∞
59.8
57
*
R1250
NOMESCO Finland
Evaluation of functional capability
7.2
58.9
90
132
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
4.3
57.8
158
395
L04AA40
ATC
cladribine; oral
+∞
55.6
53
*
L04AA52
ATC
[U] ofatumumab; parenteral
+∞
54.5
52
*
KCV12
NOMESCO Finland
Urinary bladder endoscopic botulin therapy
21.6
53.4
40
19
N28
ICPC
Limited function/disability (N)
11.4
50.4
53
48
H02AB04
ATC
methylprednisolone; systemic
2.8
49.4
294
1199
4AA23, ,
NOMESCO Finland
+∞
47.1
45
*
XCD10
NOMESCO Finland
Electrophysiological examination of eye
7.4
46.9
69
97
G04BD08
ATC
solifenacin; oral
4.4
46.8
122
293
N03AX16
ATC
[U] pregabalin
2.4
45.5
411
2040
34109
ICD-8 Finland
Other demyelinating diseases of central nervous system, Unspecified
+∞
45.0
43
*
H49.2
ICD-10 Finland
Sixth [abducent] nerve palsy
14.0
44.3
41
30
H53.1
ICD-10 Finland
Subjective visual disturbances
3.5
44.2
161
491
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
10.7
43.0
47
45
N02BF01
ATC
gabapentin; oral
3.2
42.1
183
623
R33
ICD-10 Finland
Retention of urine
4.3
41.2
110
269
L04AE01
ATC
fingolimod; oral
+∞
40.8
39
*
XKD03
NOMESCO Finland
Urethral pressure profilometry
6.9
40.1
63
95
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
5.4
39.8
80
154
L28
ICPC
Limited function/disability (L)
2.7
39.6
245
1011
R4150
NOMESCO Finland
Neuropsychological rehabilitation
9.4
37.6
45
49
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
3.2
36.8
157
527
SPAT1215
SPAT
Assessment of need for medical rehabilitation
4.2
36.7
100
248
3400A
ICD-9 Finland
Multiple sclerosis[SCLEROSIS MULTIPLEX (DISSEMINATA)]
+∞
36.6
35
*
O99.3
ICD-10 Finland
Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
4.7
36.1
85
188
N29
ICPC
Neurological sympt/complt other
6.6
36.0
59
93
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.0
35.9
621
3908
C10AC01
ATC
colestyramine; oral
5.1
35.2
76
156
SPAT1229
SPAT
Assessment of need for aid
3.7
34.8
115
328
G04BD04
ATC
oxybutynin; oral, transdermal
4.1
34.7
99
254
R35
ICD-10 Finland
Polyuria
3.6
33.8
119
354
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
3.9
33.8
102
273
N99
ICPC
Neurological disease other
9.5
33.7
40
43
AA1AD
NOMESCO Finland
CT of head and brain
2.2
33.5
358
1877
R4120
NOMESCO Finland
Occupational therapy
3.2
32.5
137
456
H48.1*G35
ICD-10 Finland
Retrobulbar neuritis in multiple sclerosis
+∞
32.4
31
*
R26.8
ICD-10 Finland
Other and unspecified abnormalities of gait and mobility
7.0
32.4
50
74
N32.82
ICD-10 Finland
Instability of the detrusor vesicae muscle
9.1
31.7
39
44
G04.9
ICD-10 Finland
Encephalitis, myelitis and encephalomyelitis, unspecified
54.1
31.4
37
7
L04AX01
ATC
azathioprine; systemic
3.6
31.0
106
309
N31.2
ICD-10 Finland
Flaccid neuropathic bladder, not elsewhere classified
9.4
30.1
36
39
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
3.4
29.7
114
358
R20.1
ICD-10 Finland
Hypoaesthesia of skin
10.2
29.2
33
33
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.8
29.2
164
640
CS494
NOMESCO Finland
Other visual field testing
5.5
28.7
56
105
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.5
28.6
192
819
R4110
NOMESCO Finland
Physiotherapy
2.0
28.6
414
2412
J01EA01
ATC
trimethoprim; systemic
2.0
28.3
427
2522
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.0
27.9
411
2406
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.3
27.8
235
1112
TKC20
NOMESCO Finland
Catheterisation of bladder
3.5
27.7
99
297
G04BD07
ATC
tolterodine; oral
4.1
27.5
77
195
G36.0
ICD-10 Finland
Neuromyelitis optica [Devic]
+∞
27.2
26
*
A28
ICPC
Limited function/disability NOS
2.6
26.7
170
706
N06AX21
ATC
duloxetine; oral
2.3
26.5
239
1161
N06AX16
ATC
venlafaxine; oral
2.1
26.5
301
1602
N32.83
ICD-10 Finland
Nozzle synergy in the bladder neck
52.7
26.3
31
6
N05CF01
ATC
zopiclone; oral
1.9
26.1
464
2882
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
5.9
25.5
46
80
G04BD11
ATC
fesoterodine; oral
5.9
25.5
46
80
A02BC02
ATC
pantoprazole; systemic
1.8
24.4
995
7829
G37.0
ICD-10 Finland
Diffuse sclerosis
+∞
24.0
23
*
Z3226
NOMESCO Finland
Physiotherapist
2.0
23.5
284
1541
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
4.8
23.0
52
111
34099
ICD-8 Finland
Multiple sclerosis
+∞
23.0
22
*
L01BB04
ATC
cladribine; systemic
+∞
23.0
22
*
R42
ICD-10 Finland
Dizziness and giddiness
2.0
22.7
311
1760
SPAT1231
SPAT
Assessment of adjustments needed in living environment
7.6
22.5
32
43
G95.8
ICD-10 Finland
Other specified diseases of spinal cord
35.6
22.1
28
8
H51.2
ICD-10 Finland
Internuclear ophthalmoplegia
+∞
21.9
21
*
N03AF01
ATC
carbamazepine; oral, rectal
3.1
21.7
93
312
N31.1
ICD-10 Finland
Reflex neuropathic bladder, not elsewhere classified
21.1
21.3
31
15
Z3231
NOMESCO Finland
Registered nurse
1.8
21.2
398
2487
Z2445
NOMESCO Finland
Psychologist
3.0
21.1
97
339
R39.1
ICD-10 Finland
Other difficulties with micturition
4.4
21.0
53
124
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
3.3
20.9
82
261
N31.8
ICD-10 Finland
Other neuromuscular dysfunction of bladder
21.8
20.8
30
14
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.6
19.9
118
472
4AA36, ,
NOMESCO Finland
+∞
19.8
19
*
34108
ICD-8 Finland
Other demyelinating diseases of central nervous system, Alii definiti
+∞
19.8
19
*
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
3.7
19.7
62
171
G82.2
ICD-10 Finland
Paraplegia, unspecified
18.0
19.6
30
17
Z2446
NOMESCO Finland
Social worker
2.5
19.4
124
514
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
3.0
19.3
90
317
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.5
18.5
125
532
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.2
18.1
161
773
N39.4
ICD-10 Finland
Other specified urinary incontinence
2.5
17.8
121
517
G37.1
ICD-10 Finland
Central demyelination of corpus callosum
+∞
17.7
17
*
SPAT1216
SPAT
Assessment of functional ability
2.1
17.5
170
844
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.0
17.5
214
1157
G81.9
ICD-10 Finland
Hemiplegia, unspecified
6.0
17.5
31
53
G50.0
ICD-10 Finland
Trigeminal neuralgia
4.3
17.0
44
105
R20.0
ICD-10 Finland
Anaesthesia of skin
6.2
16.4
28
46
N03AF02
ATC
oxcarbazepine; oral
3.1
16.1
69
232
RS221, ,
NOMESCO Finland
4.9
15.7
34
70
G36.8
ICD-10 Finland
Other specified acute disseminated demyelination
+∞
15.6
15
*
L04AX09
ATC
diroximel fumarate; oral
+∞
15.6
15
*
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
15.6
334
2145
M03BX02
ATC
tizanidine; oral
1.6
15.6
985
8179
U13
ICPC
Bladder symptom/complaint other
3.6
15.5
51
145
N06AA09
ATC
amitriptyline; systemic
2.2
15.3
137
658
AA1BM
NOMESCO Finland
MRI examination of brain with 3 Tesla magnet
4.7
15.2
35
76
G04CA02
ATC
tamsulosin; oral
2.0
15.2
168
875
R56.8
ICD-10 Finland
Other and unspecified convulsions
2.7
15.2
81
307
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
2.5
15.1
93
379
N18
ICPC
Paralysis/weakness
5.2
15.1
31
61
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
3.7
15.0
47
129
H53.4
ICD-10 Finland
Visual field defects
4.2
15.0
40
98
N30.0
ICD-10 Finland
Acute cystitis
1.8
14.9
245
1456
XF400
NOMESCO Finland
ECG with 12 standard connections
2.0
14.8
182
984
N31.0
ICD-10 Finland
Uninhibited neuropathic bladder, not elsewhere classified
25.3
14.7
20
8
RS222, ,
NOMESCO Finland
5.6
14.3
27
49
H47.0
ICD-10 Finland
Disorders of optic nerve, not elsewhere classified
27.5
14.3
19
7
H55
ICD-10 Finland
Nystagmus and other irregular eye movements
13.5
14.2
24
18
R5110, ,
SPAT
2.6
13.9
82
327
R51.80
ICD-10 Finland
Headache
1.7
13.9
284
1794
R60.0
ICD-10 Finland
Localized oedema
2.0
13.6
146
752
G04.8
ICD-10 Finland
Other encephalitis, myelitis and encephalomyelitis
34.4
13.5
17
5
N02BF02
ATC
pregabalin; oral
2.3
13.2
98
435
G61.0
ICD-10 Finland
Guillain-Barré syndrome
12.3
13.1
23
19
U04
ICPC
Incontinence urine
2.8
13.1
64
232
R27.0
ICD-10 Finland
Ataxia, unspecified
22.7
12.9
18
8
H02AB06
ATC
prednisolone; systemic
1.5
12.9
656
5115
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
4.1
12.6
34
84
H02AB07
ATC
prednisone; oral
1.9
12.5
182
1039
Z2221
NOMESCO Finland
Medical doctor
1.6
12.5
415
2951
H53.9
ICD-10 Finland
Visual disturbance, unspecified
2.9
12.3
57
201
H47.2
ICD-10 Finland
Optic atrophy
16.0
12.1
19
12
R20.8
ICD-10 Finland
Other and unspecified disturbances of skin sensation
4.4
11.7
29
67
NA7CM
NOMESCO Finland
Spine and spinal cord extensive MRI examination with 3 Tesla magnet
65.5
11.6
13
*
XCK10
NOMESCO Finland
Photography of fundus of eye
2.1
11.6
112
555
36703
ICD-8 Finland
Inflammation of optic nerve and retina, Neuritis optica, retrobulbaris
+∞
11.5
11
*
R15
ICD-10 Finland
Faecal incontinence
3.5
11.4
39
114
G40.9
ICD-10 Finland
Epilepsy, unspecified
2.8
11.4
55
198
6BA02, ,
NOMESCO Finland
15.2
11.3
18
12
R26.0
ICD-10 Finland
Ataxic gait
35.3
11.3
14
*
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
9.7
11.3
22
23
A06AD11
ATC
lactulose; oral
1.9
11.2
142
774
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.9
11.2
145
797
H25.8
ICD-10 Finland
Other senile cataract
2.5
11.0
71
296
H30.2
ICD-10 Finland
Posterior cyclitis
14.0
11.0
18
13
H57.1
ICD-10 Finland
Ocular pain
2.4
10.9
74
316
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
1.9
10.8
136
740
J05AB11
ATC
valaciclovir; oral
1.7
10.8
216
1351
G97.1
ICD-10 Finland
Other reaction to spinal and lumbar puncture
17.9
10.7
16
9
J01CA08
ATC
pivmecillinam; oral
1.4
10.6
633
5036
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
2.4
10.5
75
328
3773B
ICD-9 Finland
Disorders of optic nerve and visual pathways, Optic neuritis[NEURITIS RETROBULBARIS]
110.8
10.4
11
*
TKC10
NOMESCO Finland
Percutaneous puncture of bladder
8.9
10.3
21
24
SPAT1167
SPAT
Insertion of urinary catheter
4.1
10.2
27
66
NA1CM
NOMESCO Finland
Cervical spine extensive MRI examination with 3 Tesla magnet
13.2
10.2
17
13
N02AX02
ATC
tramadol; systemic, rectal
1.4
10.1
536
4161
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.9
9.9
128
702
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
9.9
600
4765
WW400
NOMESCO Finland
Plasmaferesis
26.2
9.8
13
5
R32
ICD-10 Finland
Unspecified urinary incontinence
3.4
9.8
34
101
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
3.5
9.6
32
92
H50.52
ICD-10 Finland
Exophoria
3.7
9.6
30
83
N06AB04
ATC
citalopram; systemic
1.5
9.5
298
2075
SPAT1293
SPAT
Other function in accordance with rehabilitation guidance nomenclature
9.1
9.5
19
21
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
3.0
9.4
42
145
G95.9
ICD-10 Finland
Disease of spinal cord, unspecified
17.6
9.4
14
8
G37.5
ICD-10 Finland
Concentric sclerosis [Baló]
+∞
9.4
9
*
3418X
ICD-9 Finland
Other demyelinating diseases of central nervous system
+∞
9.4
9
*
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.9
9.3
117
636
SPAT1301
SPAT
No procedures
1.5
9.3
380
2795
C03CA01
ATC
furosemide; systemic
1.6
9.1
215
1400
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
10.1
9.0
17
17
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
2.4
8.9
61
262
J01MA02
ATC
ciprofloxacin; systemic
1.4
8.9
465
3581
N06
ICPC
Sensation disturbance other
4.0
8.9
25
64
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
2.3
8.8
66
295
R13
ICD-10 Finland
Dysphagia
2.1
8.8
87
435
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.6
8.7
203
1318
G57.3
ICD-10 Finland
Lesion of lateral popliteal nerve
3.5
8.7
29
84
H20.1
ICD-10 Finland
Chronic iridocyclitis
4.4
8.6
21
48
K59.09
ICD-10 Finland
Constipation, unspecified
2.2
8.6
73
344
ABD30
NOMESCO Finland
Implantation of spinal stimulation device
4.8
8.6
19
40
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.8
8.5
128
738
H04.10
ICD-10 Finland
Dry eye syndrome
1.7
8.5
160
984
N06AB10
ATC
escitalopram; oral
1.5
8.5
344
2524
KA1AE
NOMESCO Finland
Kidney ultrasound examination
3.2
8.4
33
106
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.6
8.4
217
1445
D64.9
ICD-10 Finland
Anaemia, unspecified
2.0
8.3
89
458
N06AX11
ATC
mirtazapine; oral
1.4
8.3
460
3570
R25.2
ICD-10 Finland
Cramp and spasm
3.0
8.3
36
123
N02BE01
ATC
paracetamol; systemic, rectal
1.5
8.2
1277
11779
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
2.7
8.2
44
169
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
3.2
8.1
31
98
R2120
NOMESCO Finland
Counselling and guidance concerning rehabilitation services and social security
6.9
8.1
19
28
SPAT1263
SPAT
Sampling
1.4
8.0
560
4516
R52.2
ICD-10 Finland
Other chronic pain
2.3
8.0
60
269
Z3229
NOMESCO Finland
Other healthcare associate professional
1.9
8.0
97
523
U08
ICPC
Urinary retention
4.3
7.9
20
47
TPH04
NOMESCO Finland
Cathetrisation of vein
1.5
7.9
254
1773
ZXE21
NOMESCO Finland
Procedure duration at least 3 but less than 4 hours
6.6
7.9
19
29
U29
ICPC
Urinary symptom/complaint other
2.8
7.9
37
132
Z43.5
ICD-10 Finland
Attention to cystostomy
13.1
7.9
13
10
RS121, ,
NOMESCO Finland
6.1
7.8
20
33
S97
ICPC
Chronic ulcer skin
2.3
7.8
56
246
N04BD01
ATC
selegiline; oral
4.5
7.7
18
40
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.4
7.6
481
3808
J01MA12
ATC
levofloxacin; systemic
1.6
7.6
197
1312
WX110
NOMESCO Finland
Infiltration anesthesia
1.4
7.6
1067
9571
N30.9
ICD-10 Finland
Cystitis, unspecified
2.0
7.6
82
425
E87.6
ICD-10 Finland
Hypokalaemia
2.5
7.5
45
182
359
Kela drug reimbursment
Mirabegroni
10.1
7.5
14
14
JC2KB
NOMESCO Finland
Functional X-ray examination of swallowing
4.3
7.5
19
45
N04BC05
ATC
pramipexole; oral
2.0
7.5
84
441
XA402
NOMESCO Finland
ENMG
2.6
7.4
41
160
R53
ICD-10 Finland
Malaise and fatigue
1.4
7.4
326
2423
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
2.1
7.4
70
346
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.0
7.3
82
431
N05BA01
ATC
diazepam; systemic, rectal
1.6
7.2
162
1042
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.4
7.2
328
2451
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
4.5
7.2
17
38
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
2.7
7.2
38
145
WX408
NOMESCO Finland
General anesthesy, balanced
1.4
7.1
321
2397
F10.25
ICD-10 Finland
Alcohol dependence continuous use
3.1
7.0
28
91
U07
ICPC
Urine symptom/complaint other
2.0
7.0
78
408
A02BA02
ATC
ranitidine; systemic
1.5
7.0
205
1402
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
2.5
7.0
43
177
U05
ICPC
Urination problems other
2.3
6.9
51
228
XX1ZW
NOMESCO Finland
Very extensive written report from radiologist
8.3
6.8
14
17
N05BA04
ATC
oxazepam; oral
1.4
6.8
343
2606
119
Kela drug reimbursment
Trigeminal neuralgia or glossofaryngeusneuralgia
9.4
6.8
13
14
J01AA02
ATC
doxycycline; systemic
1.4
6.8
1074
9710
Z01.2
ICD-10 Finland
Dental examination
1.3
6.8
663
5590
R4110, ,
SPAT
1.8
6.8
102
589
SPAT1234
SPAT
Support of social functional capacity
2.2
6.7
53
243
R93.0
ICD-10 Finland
Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified
16.8
6.7
10
6
G96.9
ICD-10 Finland
Disorder of central nervous system, unspecified
16.8
6.7
10
6
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.3
6.7
809
7023
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
2.2
6.7
52
238
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.6
6.7
164
1079
N03AX14
ATC
levetiracetam; systemic
2.6
6.6
38
151
G51.0
ICD-10 Finland
Bell palsy
2.5
6.6
39
157
G04BD10
ATC
darifenacin; oral
7.8
6.6
14
18
R60.9
ICD-10 Finland
Oedema, unspecified
2.1
6.6
61
299
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.6
6.6
142
905
ZXA10
NOMESCO Finland
Bilateral
1.5
6.5
192
1315
X59
ICD-10 Finland
Exposure to unspecified factor
1.5
6.5
249
1800
R2110
NOMESCO Finland
Giving the first information
1.7
6.5
105
620
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.4
6.5
321
2432
F10.31
ICD-10 Finland
Withdrawal symptoms caused by alcohol with seizures
5.7
6.5
17
30
NGF00
NOMESCO Finland
Excision of plica of synovy of knee
2.7
6.4
33
124
RS340, ,
NOMESCO Finland
70.1
6.4
7
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.4
6.4
329
2505
A06AC51
ATC
ispaghula, combinations; oral
2.1
6.4
60
295
SPAT1262
SPAT
Handing over of treatment supplies
1.5
6.4
179
1211
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.7
6.4
119
731
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
1.9
6.3
83
459
OAB50, ,
SPAT
2.0
6.3
64
325
ABD40
NOMESCO Finland
Implantation of spinal injection device
+∞
6.3
6
*
G37.4
ICD-10 Finland
Subacute necrotizing myelitis
+∞
6.3
6
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.6
6.2
144
933
Z93.5
ICD-10 Finland
Cystostomy status
26.8
6.2
8
*
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
2.8
6.2
29
104
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
4.0
6.2
17
43
Z73.6
ICD-10 Finland
Limitation of activities due to disability
6.3
6.2
15
24
TNX34
NOMESCO Finland
Major custom molded cast, unspecified region
3.4
6.1
21
62
M79.6
ICD-10 Finland
Pain in limb
1.3
6.1
559
4646
H47.1
ICD-10 Finland
Papilloedema, unspecified
4.1
6.1
16
39
WX100
NOMESCO Finland
Conjunctival surface anesthesia
1.9
6.1
78
429
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
2.8
6.1
29
105
XF600
NOMESCO Finland
Bloodpressure measurement
1.9
6.1
70
372
CA1CM
NOMESCO Finland
Eye and orbita extensive MRI examination with 3 Tesla magnet
10.1
6.0
11
11
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.2
6.0
50
235
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.6
6.0
145
949

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
324
194
20.95
307.65
1.2
1.2
—
—
—
0
0
337
127
33.81
307.65
1.1
1.1
—
—
—
0
0
602
917
10.21
307.65
3.3
2.6
10.16
10.60
g/l
1.89
549
843
354
272
16.66
307.65
1.2
1.5
9.10
14.43
e6/l
0.67
263
218
373
248
19.61
307.65
1.2
1.6
—
—
—
0
0
367
95
50.61
307.65
1.1
1.1
210.38
228.39
mg/l
0.57
323
80
377
102
48.82
307.65
1.2
1.2
50.45
36.53
mg/l
2.10
301
84
419
300
18.90
307.65
1.2
1.4
412.89
501.08
mg/l
2.21
408
284
341
276
15.64
307.65
1.2
1.3
3.53
3.72
mmol/l
1.99
320
259
354
272
16.66
307.65
1.2
1.6
617.93
1885.48
e6/l
0.58
278
224
306
84
45.36
307.65
1.8
1.5
—
—
—
0
0
216
116
21.54
278.95
1.2
1.7
—
—
—
0
0
197
90
25.00
272.14
3.7
2.2
1.37
1.30
e9/l
0.32
173
82
141
20
77.61
262.68
1.0
1.1
4.97
5.47
mg/g
0.38
132
20
158
64
27.44
227.78
4.2
2.2
0.25
0.20
e9/l
2.10
134
57
159
66
26.79
227.18
4.2
2.2
446.51
583.18
e6/l
1.15
134
57
445
923
6.40
215.98
2.6
2.3
26.46
22.87
au/ml
0.17
14
97
427
854
6.56
215.12
1.4
1.3
12.74
38.78
au/ml
—
8
53
182
128
16.02
204.58
1.3
1.8
—
—
—
0
0
365
721
6.35
184.33
3.2
1.7
1.19
1.38
g/l
0.86
359
668
125
59
23.00
169.25
1.2
1.1
1463.76
1497.47
miu/ml
0.07
125
59
1115
5824
4.43
152.95
12.3
6.2
—
—
—
0
0
132
91
15.79
149.25
1.2
1.5
1.68
1.91
mmol/l
2.30
126
86
1067
5570
4.07
142.31
11.3
5.8
0.76
0.68
%
6.34
1044
5231
1133
6197
4.25
140.19
11.6
5.7
0.56
0.55
e9/l
1.96
1039
5476
1132
6205
4.23
139.18
11.6
5.7
0.04
0.04
e9/l
0.09
1037
5473
86
24
37.92
138.56
3.2
1.5
42.97
210.00
e6/l
1.86
37
14
1084
5802
4.03
137.28
11.3
5.7
2.96
2.80
%
1.80
1062
5471
1088
5846
4.03
136.79
11.4
6.0
8.95
8.11
%
18.10
1066
5530
1142
6437
4.11
131.33
11.7
6.0
0.18
0.18
e9/l
0.01
1052
5777
1139
6422
4.09
130.60
11.6
5.7
1.71
1.97
e9/l
12.86
1049
5814
87
32
28.78
128.86
2.2
2.1
—
—
—
0
0
1097
6067
3.90
128.69
11.3
5.7
26.93
29.16
%
10.97
1075
5753
1083
5992
3.81
125.73
10.9
5.5
58.40
56.57
%
6.58
1060
5672
91
58
16.63
106.81
1.1
1.6
95.53
71.56
%
—
15
9
1158
7091
3.66
105.89
12.6
8.8
3.79
4.01
e9/l
3.60
1060
6260
651
2877
3.21
104.09
4.0
2.6
—
—
—
0
0
690
3166
3.16
103.19
4.3
2.8
15.07
107.88
e6/l
2.25
579
2378
541
2170
3.32
101.45
3.4
2.3
4.79
7.13
e6/l
3.59
510
1933
647
2887
3.16
101.15
4.1
2.7
0.13
0.34
e6/l
5.73
537
2135
752
3891
2.85
86.41
5.3
3.2
41.86
74.04
e6/l
1.11
602
2588
491
2047
3.07
83.75
3.5
2.5
537.68
535.44
mosm/kgh2o
0.08
452
1764
352
1213
3.48
82.47
1.3
1.5
—
—
—
0
0
872
4964
2.77
81.79
2.5
2.2
86.07
74.05
nmol/l
20.89
817
4607
802
4427
2.72
79.14
3.8
4.6
37.35
36.61
g/l
3.56
750
4158
1155
7876
2.94
71.72
7.4
3.7
46.50
558.77
e6/l
—
10
80
890
5465
2.52
66.17
12.7
8.3
0.00
0.00
e9/l
0.38
755
4499
1190
8410
2.91
65.83
6.8
3.8
—
—
—
0
0
53
41
13.36
55.61
1.2
1.1
185.69
576.13
ng/l
—
16
8
410
1881
2.62
55.11
1.5
1.6
—
—
—
0
0
574
3119
2.35
52.91
3.9
2.4
—
—
—
0
0
339
1510
2.60
47.66
1.7
2.1
29.20
29.41
s
0.39
322
1461
365
1692
2.52
47.15
3.5
2.4
0.85
1.24
e6/l
0.63
208
917
236
886
2.97
46.00
5.4
4.2
0.02
0.46
%
0.60
44
210
241
932
2.88
44.42
5.5
4.2
0.02
0.15
%
3.62
49
254
248
983
2.82
43.61
5.4
4.1
0.73
1.05
%
0.68
56
307
230
901
2.83
41.22
5.3
4.0
0.22
0.73
%
4.13
49
261
884
6134
2.05
40.11
5.4
3.1
0.00
0.01
estimate
1.06
249
1123
187
663
3.08
40.08
1.7
2.6
68.67
67.98
g/l
0.65
176
622
333
1592
2.40
39.49
3.8
2.5
5.34
3.07
e6/l
1.83
179
824
875
6078
2.04
39.24
5.3
3.1
0.00
0.00
estimate
0.80
255
1217
101
240
4.44
39.22
3.8
4.0
3.87
4.17
e9/l
0.74
101
240
874
6086
2.03
38.71
6.8
4.2
0.00
0.00
estimate
0.35
252
1183
379
1937
2.27
38.37
1.4
1.4
425.00
547.99
titre
1.08
88
383
101
246
4.33
37.98
3.9
4.3
59.58
57.17
%
1.21
101
246
522
3041
2.09
37.80
2.4
2.1
144.77
194.08
u/l
1.04
501
2888
910
6465
2.02
37.64
5.1
4.4
6.15
6.50
mmol/l
6.90
860
5928
510
2957
2.09
37.31
1.7
1.7
—
—
—
0
0
115
324
3.76
35.40
1.3
1.2
—
—
—
0
0
481
2780
2.07
35.10
2.3
1.4
2.14
2.28
g/l
1.39
371
1795
53
79
6.92
34.10
4.2
2.6
50.41
46.23
%
0.81
41
40
732
4943
1.93
33.77
4.3
2.9
5.89
5.90
ph
0.01
51
534
63
115
5.67
33.19
1.1
1.9
—
—
—
0
0
655
4350
1.89
30.99
7.2
9.1
1.12
1.12
inr
0.06
229
1406
811
5824
1.84
29.38
5.0
5.9
9.49
10.44
umol/l
3.69
788
5520
228
1082
2.30
26.71
6.7
3.3
—
—
—
0
0
654
4514
1.79
25.96
6.4
5.6
1.22
1.21
mmol/l
0.21
588
4175
1111
8971
1.89
25.82
6.5
7.1
72.70
74.54
u/l
1.08
1053
8494
476
3021
1.84
24.71
7.9
6.6
—
—
—
0
0
547
3621
1.80
24.70
1.9
1.9
—
—
—
0
0
138
540
2.71
24.36
1.8
2.2
—
—
—
0
0
431
2695
1.84
23.24
4.7
3.1
—
—
—
0
0
204
977
2.26
23.23
2.5
2.2
687.50
5367.64
u/l
5.90
59
407
702
5062
1.72
23.02
7.2
6.2
1.22
1.21
mmol/l
0.59
563
4315
450
2862
1.81
22.89
3.7
3.5
97.13
96.17
%
0.40
438
2770
1424
12770
2.82
22.82
14.6
11.1
17.63
20.23
mg/l
2.45
1138
9849
1096
9049
1.76
20.85
3.8
3.8
10.32
9.90
mm/h
0.54
1021
8498
1393
12498
2.37
19.87
14.7
11.5
139.56
139.58
mmol/l
0.14
1369
12180
1395
12538
2.37
19.56
14.7
11.6
3.91
3.93
mmol/l
1.76
1366
12196
473
3192
1.70
18.88
6.8
3.3
0.00
0.01
estimate
1.49
254
1163
446
3010
1.68
17.57
3.4
3.7
7.40
7.40
ph
0.48
101
598
62
188
3.40
17.08
1.3
1.9
—
1462.86
—
0
7
1460
13550
2.96
16.46
14.8
8.9
26.40
26.29
u/l
0.09
1430
13192
411
2776
1.66
15.88
3.2
3.0
—
—
—
0
0
556
4060
1.58
15.53
1.8
1.8
96.26
97.79
pmol/l
0.36
306
2194
486
3525
1.56
13.58
5.1
2.7
—
—
—
0
0
1078
9284
1.55
13.22
4.2
2.9
40.26
40.49
u/l
0.04
1032
8867
564
4293
1.50
12.30
3.7
3.3
27.94
29.85
u/l
1.37
548
4098
45
138
3.33
12.23
1.4
1.4
6.42
6.74
g/l
0.22
32
94
45
138
3.33
12.23
1.4
1.4
2.99
2.99
g/l
0.00
32
93
45
138
3.33
12.23
1.4
1.4
0.31
0.39
g/l
1.19
32
93
45
142
3.24
11.70
1.5
1.4
—
—
—
0
0
28
66
4.30
11.04
1.6
3.6
718.96
820.65
u/ml
0.14
28
66
57
215
2.72
10.85
1.6
1.7
0.64
0.78
g/l
0.45
42
161
499
3780
1.48
10.83
3.1
2.9
36.83
32.44
ng/l
0.10
279
2017
1254
11386
1.58
10.21
20.1
13.2
14.36
14.40
%
0.10
1240
11195
348
2489
1.52
9.87
4.4
4.0
—
—
—
0
0
248
1646
1.61
9.79
3.2
3.4
0.82
0.83
mmol/l
0.21
233
1569
1292
11854
1.60
9.60
5.3
4.7
1.72
2.12
mu/l
1.33
1213
11189
77
355
2.23
9.56
1.3
1.3
55.00
92.56
titre
—
10
39
156
922
1.77
9.52
2.8
2.4
4.06
6.01
e9/l
1.84
133
810
57
236
2.47
9.04
1.6
1.8
39.26
38.91
g/l
0.15
52
219
235
1568
1.59
9.04
1.6
1.6
1132.06
1193.73
nmol/l
0.31
177
1243
1433
13588
1.95
8.60
14.1
10.2
—
—
—
0
0
13
8
16.38
8.55
1.3
4.0
—
—
—
0
0
99
526
1.94
8.47
1.6
1.3
—
—
—
0
0
62
282
2.25
7.99
1.7
1.9
11.57
10.67
g/l
0.49
57
264
458
3588
1.40
7.75
2.4
2.5
52.59
55.67
u/l
1.51
427
3359
136
822
1.72
7.68
3.0
3.2
1.22
1.23
mmol/l
0.90
117
715
65
307
2.17
7.66
1.9
2.8
—
—
—
0
0
301
2195
1.46
7.56
1.5
1.4
19.35
20.84
nmol/l
1.06
271
1945
196
1333
1.54
6.87
2.1
2.8
6.12
7.37
umol/l
0.76
170
1143
1068
11602
0.73
6.77
21.5
13.7
332.59
332.89
g/l
0.53
1061
11520
29
99
2.97
6.71
1.1
1.1
—
—
—
0
0
182
1228
1.55
6.61
6.1
5.8
1.00
1.04
mmol/l
1.30
169
1159
443
3539
1.36
6.43
2.4
3.2
2.34
2.35
mmol/l
0.48
387
3234
76
409
1.90
6.32
1.3
1.2
95.40
32.38
u/ml
—
5
24
49
225
2.22
6.24
1.4
2.0
—
3.40
—
0
5
147
968
1.57
5.95
4.7
3.6
—
—
—
0
0
18
49
3.71
5.93
4.1
2.4
—
—
—
0
0
10
9
11.17
5.79
1.1
1.0
—
—
—
0
0
52
254
2.08
5.70
1.1
1.1
—
—
—
0
0
1112
10217
1.33
5.58
4.3
4.1
14.71
14.39
pmol/l
4.19
1019
9582
42
190
2.24
5.57
1.6
1.3
—
—
—
0
0
1488
14478
2.32
5.53
26.0
16.3
40.59
40.80
%
0.26
1422
13796
1178
12512
0.74
5.40
3.7
3.7
1.49
1.49
mmol/l
0.00
1090
11887
44
208
2.15
5.26
1.4
1.4
—
—
—
0
0
120
776
1.59
5.26
6.8
8.0
7.28
7.96
mmol/l
0.76
115
745
1487
14488
2.21
5.09
25.7
16.3
265.71
261.12
e9/l
2.04
1471
14215
12
19
6.36
5.08
1.1
1.0
87.00
61.83
%
—
6
6
1488
14503
2.23
5.06
25.6
16.2
90.65
90.27
fl
2.98
1477
14363
1488
14505
2.23
5.03
25.5
16.2
30.21
30.13
pg
1.15
1477
14363
1488
14507
2.22
4.99
25.7
16.3
4.53
4.54
e12/l
0.47
1472
14215
31
129
2.43
4.98
1.3
1.5
49.17
71.26
mmol/l
2.90
23
113
1488
14508
2.22
4.97
25.8
16.3
6.57
6.70
e9/l
1.21
1469
14209
125
829
1.55
4.93
6.0
3.2
—
—
—
0
0
1488
14513
2.20
4.88
25.8
16.4
135.92
136.14
g/l
0.29
1477
14369
66
376
1.79
4.66
1.4
1.3
3.96
9.78
u/ml
—
10
65
1204
12690
0.75
4.58
4.0
4.0
2.87
2.89
mmol/l
0.35
1110
12032
24
93
2.61
4.48
1.1
1.2
—
—
—
0
0
47
244
1.96
4.43
1.2
1.3
3.83
5.75
u/ml
0.47
18
102
169
1221
1.43
4.39
2.2
2.1
359.92
372.92
nmol/l
0.43
155
1142
87
545
1.63
4.38
1.6
1.6
—
—
—
0
0
190
1404
1.40
4.36
1.4
1.4
—
—
—
0
0
1191
12553
0.76
4.34
3.7
3.8
4.75
4.80
mmol/l
1.07
1109
11965
33
151
2.21
4.32
1.2
1.7
—
21.00
—
0
9
104
683
1.56
4.31
1.1
1.3
235.80
217.51
miu/ml
0.18
42
359
64
371
1.76
4.29
1.4
1.3
2.14
2.57
u/ml
—
7
40
184
1368
1.39
4.07
2.6
1.6
—
—
—
0
0
24
99
2.45
3.98
3.7
3.6
—
—
—
0
0
71
1123
0.61
3.96
1.6
1.7
—
—
—
0
0
1140
12049
0.78
3.94
3.4
3.4
1.24
1.27
mmol/l
0.67
1055
11410
143
1957
0.70
3.92
1.2
1.3
—
—
—
0
0
58
336
1.75
3.92
1.4
1.9
1.43
1.42
g/l
0.05
51
293
133
940
1.45
3.90
2.3
2.4
0.22
0.23
g/l
0.09
127
883
236
1838
1.34
3.90
3.1
3.3
237.13
492.77
ng/l
0.81
125
1118
97
643
1.54
3.88
2.4
2.7
67.80
74.68
e9/l
1.13
66
472
8
11
7.31
3.86
1.1
1.0
—
—
—
0
0
32
153
2.11
3.80
1.5
1.2
—
—
—
0
0
16
55
2.93
3.74
1.3
1.1
—
—
—
0
0
268
2140
1.31
3.71
1.6
1.6
456.26
26168155.97
pmol/l
2.06
232
1884
71
444
1.63
3.64
1.2
1.2
—
—
—
0
0
8
13
6.18
3.50
1.5
1.2
—
—
—
0
0
40
215
1.88
3.47
2.6
2.8
2.50
2.25
mmol/l
0.29
31
132
17
64
2.67
3.40
1.4
1.7
140.59
141.84
nmol/l
0.04
17
64
44
246
1.81
3.38
1.0
1.1
—
—
—
0
0
8
14
5.74
3.34
1.5
1.1
—
—
—
0
0
461
5293
0.81
3.31
2.3
2.4
—
—
—
0
0
13
38
3.44
3.31
1.2
1.2
—
—
—
0
0
66
420
1.60
3.19
4.1
3.2
—
—
—
0
0
55
335
1.67
3.16
2.1
2.1
2.84
2.41
ug/l
0.07
42
307
17
67
2.55
3.13
2.1
2.0
2.56
2.76
u/field
—
9
34
9
20
4.52
3.11
2.2
1.1
—
—
—
0
0
50
299
1.70
3.08
2.8
2.1
—
—
—
0
0
19
80
2.39
3.06
4.7
3.0
38178.95
39560.60
ug/l
0.26
19
80
73
481
1.54
3.06
1.6
2.1
20.87
20.93
s
0.05
62
410
195
1531
1.31
3.05
2.2
1.9
—
—
—
0
0
14
340
0.41
3.02
1.1
1.1
0.28
1.81
u/ml
—
7
155
148
1118
1.36
3.01
1.2
1.2
—
—
—
0
0
43
250
1.74
2.94
2.5
2.7
7.43
7.42
ph
1.15
43
225
21
95
2.23
2.90
2.7
2.8
1.44
1.55
g/24h
—
9
53
12
300
0.40
2.79
1.1
1.0
3.61
2.88
u/ml
—
7
136
80
1141
0.68
2.79
1.5
1.4
—
—
—
0
0
130
975
1.36
2.78
12.8
9.1
5.00
5.08
kpa
0.44
119
934
130
975
1.36
2.78
12.8
9.1
12.64
12.97
kpa
0.32
120
937
38
217
1.77
2.78
1.2
1.9
4.09
5.31
mmol/24h
1.84
33
195
125
933
1.37
2.76
3.2
2.5
1.63
1.79
%
1.45
109
844
69
463
1.51
2.69
16.3
12.8
—
—
—
0
0
189
1509
1.29
2.63
2.5
2.2
2.39
2.42
g/l
0.34
176
1407
28
148
1.91
2.61
1.8
1.6
—
—
—
0
0
10
30
3.35
2.60
3.8
2.2
—
—
—
0
0
7
15
4.68
2.60
2.0
2.5
0.43
0.73
u/field
—
7
15
17
74
2.31
2.58
1.5
1.2
—
—
—
0
0
326
2778
1.22
2.56
2.2
2.0
2.79
2.81
mg/l
0.03
285
2415
5
7
7.16
2.55
1.0
1.0
—
—
—
0
0
128
972
1.35
2.55
12.9
9.1
1.26
0.90
mmol/l
0.48
97
761
340
2912
1.22
2.54
1.6
1.8
0.88
0.91
mg/l
0.07
223
2163
21
101
2.09
2.53
2.3
2.8
—
—
—
0
0
20
95
2.12
2.49
1.1
1.0
—
—
—
0
0
43
265
1.64
2.43
1.8
2.3
—
—
—
0
0
173
1381
1.29
2.42
2.6
2.3
23.64
24.27
%
0.21
150
1204
32
182
1.77
2.40
1.3
1.3
—
41.25
—
0
12
204
1665
1.26
2.38
2.6
2.2
13.63
14.38
umol/l
0.76
192
1562
25
133
1.89
2.32
2.5
2.8
—
—
—
0
0
12
275
0.43
2.31
1.1
1.1
4.17
4.61
u/ml
—
5
103
301
2573
1.21
2.29
6.2
3.3
1.02
1.02
kg/l
0.11
38
351
21
392
0.53
2.27
1.1
1.1
0.15
2.69
u/ml
—
8
192
163
2017
0.79
2.25
1.4
1.5
—
—
—
0
0
80
575
1.41
2.25
4.1
3.1
7.44
7.41
ph
0.68
11
71
570
5164
1.17
2.20
2.0
2.0
—
—
—
0
0
855
7992
1.16
2.17
3.2
3.0
—
—
—
0
0
111
848
1.33
2.16
14.0
9.9
96.39
96.32
%
0.05
105
825
8
25
3.21
2.09
8.0
9.9
—
—
—
0
0
18
89
2.03
2.06
1.1
1.0
—
—
—
0
0
35
215
1.64
2.04
3.7
3.7
35.00
38.34
mg/l
0.20
30
174
35
215
1.64
2.04
3.7
3.7
24.96
30.25
mg/l
0.69
30
173
370
3257
1.18
2.03
1.3
1.3
1.43
1.53
u/ml
0.06
85
919
31
186
1.68
1.98
2.5
2.1
15.77
16.65
%
0.40
11
86
128
1015
1.29
1.92
1.2
1.3
84.15
228.02
u/ml
4.38
115
948
8
28
2.87
1.86
1.0
1.1
—
—
—
0
0
8
28
2.87
1.86
1.0
1.1
—
—
—
0
0
8
28
2.87
1.86
1.0
1.1
—
—
—
0
0
17
87
1.96
1.80
1.5
1.4
15.84
28.70
umol/l
1.69
17
82
103
804
1.30
1.76
15.2
10.0
122.43
123.30
g/l
0.18
98
786
19
334
0.56
1.73
1.1
1.1
0.04
1.38
u/ml
—
6
139
21
357
0.58
1.70
1.0
1.1
0.85
6.53
u/ml
—
10
189
20
112
1.80
1.65
1.2
1.1
—
—
—
0
0
5
14
3.58
1.61
1.2
1.3
—
—
—
0
0
6
20
3.01
1.58
1.7
2.4
—
—
—
0
0
674
6293
1.13
1.54
2.9
2.8
96.46
89.26
ug/l
0.39
644
5944
20
115
1.75
1.53
1.6
1.7
269.40
283.63
mosm/kgh2o
0.65
15
92
0
42
0.00
1.52
0.0
2.0
—
78.77
—
0
5
279
2466
1.16
1.45
1.3
1.3
18.47
28.24
iu/ml
0.93
67
792
6
22
2.73
1.43
2.8
1.3
2.35
2.49
mmol/l
—
6
22
211
1826
1.18
1.43
2.1
2.5
88.95
108.26
ug/g
0.54
152
1470
9
40
2.26
1.40
1.0
1.3
—
—
—
0
0
7
29
2.42
1.39
2.3
1.4
—
—
—
0
0
17
97
1.76
1.35
1.2
2.8
—
—
—
0
0
13
68
1.92
1.33
1.1
3.3
—
—
—
0
0
63
484
1.31
1.27
2.5
2.2
—
—
—
0
0
99
1205
0.81
1.25
2.9
2.5
0.67
0.69
ug/l
0.14
70
683
238
2104
1.16
1.25
2.3
3.0
638.16
796.09
ng/l
0.53
197
1726
96
781
1.24
1.24
4.4
3.4
1.49
1.82
mmol/l
0.43
86
648
18
108
1.67
1.22
1.2
1.1
1.04
1.05
ratio
—
6
50
46
341
1.36
1.19
8.6
8.0
0.93
0.92
%
0.09
41
319
46
341
1.36
1.19
8.6
8.0
1.81
1.65
%
0.55
41
319
73
579
1.27
1.18
2.1
2.9
80.03
144.04
ng/l
2.34
64
512
92
752
1.24
1.16
3.8
2.1
—
—
—
0
0
29
199
1.47
1.15
3.4
2.6
—
—
—
0
0
98
809
1.23
1.13
14.1
7.4
1.25
1.33
mmol/l
0.25
93
790
68
538
1.28
1.13
6.1
6.6
—
—
—
0
0
7
30
2.34
1.12
1.1
1.2
—
—
—
0
0
7
30
2.34
1.12
4.1
2.3
—
—
—
0
0
45
593
0.75
1.10
1.3
1.4
—
—
—
0
0
17
104
1.64
1.09
1.1
1.1
—
—
—
0
0
8
41
1.96
1.09
1.3
1.0
—
—
—
0
0
40
295
1.37
1.08
1.2
1.3
329.19
253.21
u/ml
0.49
26
190
9
165
0.54
1.08
1.2
1.4
—
—
—
0
0
130
1109
1.19
1.08
2.7
2.4
28.54
40.28
u/l
1.85
114
948
45
590
0.76
1.07
1.3
1.4
—
—
—
0
0
85
697
1.23
1.06
4.7
3.7
87.94
78.42
ng/l
0.37
74
630
19
122
1.56
1.02
1.1
1.1
—
—
—
0
0
18
115
1.57
0.99
1.1
1.5
10.92
10.39
umol/l
0.15
18
106
44
335
1.32
0.99
1.1
1.4
25.72
22.75
u/l
0.30
35
278
256
2822
0.89
0.98
4.8
3.9
15.10
9.33
mg/mmol
0.43
162
1816
27
190
1.43
0.97
3.1
2.9
—
—
—
0
0
23
157
1.47
0.96
1.5
1.3
—
0.53
nmol/l
—
0
6
13
77
1.69
0.95
2.0
2.2
11.83
11.55
%
0.07
13
77
35
260
1.35
0.93
1.3
1.4
81.27
106.50
u/ml
—
6
50
250
2266
1.12
0.93
1.5
1.7
—
—
—
0
0
13
78
1.67
0.91
1.8
1.1
—
—
—
0
0
87
729
1.21
0.91
16.7
9.0
—
—
—
0
0
48
607
0.78
0.90
1.3
1.5
—
—
—
0
0
11
180
0.61
0.86
1.9
1.6
—
—
—
0
0
63
515
1.23
0.85
9.2
8.9
24.36
24.31
mmol/l
0.04
57
489
52
416
1.26
0.84
4.3
3.6
23.93
24.07
mmol/l
0.15
52
409
28
377
0.74
0.84
1.2
1.7
38.00
39.65
nmol/l
0.18
28
367
46
363
1.28
0.83
3.5
3.5
0.42
0.25
g/l
0.68
19
153
93
793
1.18
0.82
1.5
1.4
—
—
—
0
0
13
81
1.61
0.81
1.3
2.0
—
—
—
0
0
18
259
0.69
0.80
1.4
1.8
218.00
205.23
pmol/l
0.18
18
247
295
3188
0.91
0.79
4.2
3.2
7.49
8.01
mmol/l
1.14
246
2785
63
523
1.21
0.75
1.2
1.2
—
—
—
0
0
13
83
1.57
0.75
2.8
2.4
—
—
—
0
0
28
369
0.75
0.75
1.4
1.4
0.40
0.45
nmol/l
0.23
21
302
5
24
2.09
0.74
1.4
1.2
—
—
—
0
0
36
280
1.29
0.74
1.3
1.4
—
—
—
0
0
286
3078
0.91
0.71
1.5
1.6
1.47
1.42
mmol/l
0.41
234
2674
20
143
1.40
0.70
1.5
1.3
—
—
—
0
0
14
93
1.51
0.69
2.9
2.1
—
—
—
0
0
5
93
0.54
0.67
1.2
1.2
—
—
—
0
0
38
303
1.26
0.67
8.8
9.0
1.16
1.22
mmol/l
0.16
32
262
48
394
1.23
0.66
4.2
2.4
0.68
0.66
%
0.15
48
394
12
78
1.54
0.65
1.2
1.1
—
—
—
0
0
18
247
0.73
0.64
2.3
2.4
42.92
114.69
ug/min
1.16
12
151
251
2702
0.91
0.64
4.2
3.3
641.42
360.14
mg/l
0.30
158
1759
48
398
1.21
0.61
1.1
1.1
—
—
—
0
0
0
20
0.00
0.60
0.0
1.6
—
—
—
0
0
19
140
1.36
0.58
1.4
1.3
—
—
nmol/l
—
0
0
0
23
0.00
0.58
0.0
2.1
—
1.19
—
0
23
176
1617
1.10
0.56
1.2
1.2
—
—
—
0
0
33
406
0.81
0.55
7.0
7.9
—
—
—
0
0
57
487
1.18
0.54
3.2
2.6
—
—
—
0
0
30
240
1.26
0.54
1.2
1.2
—
—
—
0
0
131
1188
1.11
0.54
1.2
1.2
159.03
146.47
iu/ml
0.14
50
465
187
1728
1.09
0.53
2.3
2.6
2.43
2.43
mmol/l
0.16
164
1521
6
39
1.54
0.53
8.5
3.8
—
—
—
0
0
73
830
0.87
0.51
1.6
1.6
347.80
302.53
mu/l
0.35
64
745
9
64
1.41
0.51
1.1
1.1
5.00
6.49
mmol/l
—
9
57
13
92
1.42
0.50
1.0
1.5
—
—
—
0
0
46
541
0.85
0.50
1.1
1.3
12.28
10.66
u/l
0.29
38
449
6
41
1.47
0.50
1.2
1.3
—
—
—
0
0
32
262
1.23
0.48
2.3
1.5
—
—
—
0
0
7
46
1.52
0.48
1.0
1.1
—
—
—
0
0
90
807
1.12
0.47
1.3
1.2
—
—
—
0
0
43
365
1.18
0.46
4.5
3.0
—
—
—
0
0
386
4034
0.94
0.46
1.6
1.6
—
—
—
0
0
127
1385
0.91
0.46
1.4
1.3
—
—
—
0
0
21
165
1.28
0.45
4.5
4.1
—
—
—
0
0
17
220
0.77
0.45
2.9
3.3
39.14
23.80
mg/l
—
7
142
7
51
1.37
0.44
1.3
1.5
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
0.26
—
0
7
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
8
61
1.31
0.39
1.8
2.8
1736.25
1989.41
ml
—
8
56
5
35
1.43
0.39
1.0
1.1
0.02
0.12
u/ml
—
5
35
37
316
1.18
0.39
1.1
1.1
—
—
—
0
0
60
674
0.89
0.38
1.2
1.1
—
—
—
0
0
34
289
1.18
0.38
1.7
1.7
—
—
—
0
0
76
839
0.90
0.37
3.2
4.4
6.10
18.40
ug/l
0.90
56
645
599
5832
1.04
0.35
2.4
2.4
—
—
—
0
0
13
99
1.32
0.35
1.5
1.8
—
—
—
0
0
6
43
1.40
0.35
4.7
1.5
—
—
—
0
0
6
43
1.40
0.35
2.5
1.2
—
—
—
0
0
15
189
0.79
0.34
1.4
1.6
—
—
—
0
0
11
82
1.34
0.34
6.0
7.1
—
—
—
0
0
6
45
1.33
0.33
1.0
1.0
—
—
—
0
0
6
45
1.33
0.33
2.2
1.5
—
—
—
0
0
6
45
1.33
0.33
1.2
1.1
—
—
—
0
0
17
136
1.25
0.33
1.4
1.7
—
—
—
0
0
13
100
1.30
0.33
1.4
1.3
1.54
1.59
g/l
0.33
13
100
102
945
1.09
0.32
3.1
3.4
4.41
4.57
pmol/l
1.28
88
850
7
54
1.30
0.30
1.6
1.8
—
—
—
0
0
36
316
1.14
0.29
1.1
1.1
—
—
—
0
0
11
85
1.30
0.28
1.3
1.4
21.80
38.09
%
—
5
53
106
1131
0.93
0.27
1.3
1.3
27.06
25.54
iu/l
0.19
100
978
13
104
1.25
0.26
1.0
1.2
—
—
—
0
0
18
213
0.84
0.25
5.8
3.2
—
—
—
0
0
42
378
1.11
0.25
1.8
2.0
8.15
4.41
iu/l
0.62
13
145
138
1313
1.06
0.23
1.4
1.3
—
—
—
0
0
15
125
1.20
0.22
1.3
1.6
64.33
53.53
%
—
9
86
0
11
0.00
0.21
0.0
2.5
—
36.91
—
0
11
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
2.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.9
—
153.60
—
0
10
5
43
1.16
0.21
2.0
3.4
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
2.1
—
1.25
—
0
8
6
49
1.23
0.20
1.5
1.5
62.50
83.35
nmol/24h
—
6
49
287
2791
1.03
0.19
2.2
2.1
—
—
—
0
0
7
58
1.21
0.18
1.3
1.4
—
—
—
0
0
7
59
1.19
0.18
1.1
1.1
484.19
166.93
iu/ml
—
7
59
7
61
1.15
0.17
1.3
1.5
—
—
—
0
0
10
82
1.22
0.17
1.4
1.4
—
—
—
0
0
5
69
0.72
0.17
1.0
1.1
—
—
—
0
0
1199
11916
1.03
0.17
3.8
3.7
5.66
5.74
mmol/l
1.57
1102
11175
5
70
0.71
0.16
1.2
2.6
24.16
129.03
ug/l
—
5
64
61
574
1.07
0.16
5.8
2.9
—
—
—
0
0
6
76
0.79
0.15
1.7
2.5
1154.83
615.92
ml
—
6
50
6
78
0.77
0.15
1.0
1.3
158.73
166.44
pmol/l
—
6
78
210
2043
1.03
0.15
4.0
3.9
1.55
1.90
ug/l
0.97
181
1863
28
256
1.10
0.14
1.1
1.0
1.61
2.18
u/ml
0.36
12
132
79
758
1.04
0.12
3.9
2.2
—
—
—
0
0
13
114
1.14
0.11
1.6
1.5
0.89
0.96
g/l
0.29
13
114
64
668
0.96
0.10
1.1
1.1
—
—
—
0
0
28
261
1.07
0.10
1.1
1.1
—
—
—
0
0
5
46
1.09
0.09
1.4
1.3
—
—
—
0
0
294
2897
1.02
0.09
2.5
2.3
2923.21
4146.35
umol/l
0.33
260
2607
11
124
0.89
0.09
1.1
1.1
—
—
—
0
0
6
56
1.07
0.08
1.2
1.5
—
—
—
0
0
98
953
1.03
0.08
1.2
1.4
—
—
—
0
0
5
63
0.79
0.08
1.2
1.1
—
—
—
0
0
5
63
0.79
0.08
2.0
2.5
60.20
49.51
umol/l
—
5
56
159
1559
1.02
0.08
1.3
1.2
—
—
—
0
0
64
662
0.97
0.07
1.9
2.1
7.29
7.00
ug/l
0.05
54
599
74
763
0.97
0.07
1.9
2.1
12.45
12.36
nmol/l
0.03
67
703
20
186
1.08
0.07
1.2
1.2
—
—
—
0
0
7
82
0.85
0.07
1.1
1.2
—
—
—
0
0
22
206
1.07
0.07
2.5
2.5
—
—
—
0
0
24
226
1.06
0.06
1.0
1.1
1.14
2087.26
iu/ml
—
7
63
35
335
1.05
0.06
1.3
1.3
—
—
—
0
0
22
207
1.06
0.06
2.8
2.6
—
—
—
0
0
379
3757
1.01
0.06
2.2
2.1
—
—
—
0
0
10
110
0.91
0.05
1.0
1.0
—
—
—
0
0
87
854
1.02
0.04
1.2
1.2
—
—
—
0
0
10
91
1.10
0.04
1.2
1.5
5.53
6.02
mmol/l
—
10
66
10
92
1.09
0.03
1.7
1.3
75.00
72.28
umol/l
—
10
92
80
812
0.98
0.03
3.9
2.2
—
—
—
0
0
38
390
0.97
0.02
1.2
1.5
58.33
112.47
pmol/l
1.04
38
384
13
122
1.07
0.02
1.2
1.8
20.62
19.89
nmol/l
0.16
13
115
64
650
0.98
0.02
4.4
2.2
—
—
—
0
0
236
2373
0.99
0.02
1.3
1.3
3.42
10.27
u/ml
3.61
84
1000
10
93
1.08
0.02
2.5
2.3
—
—
—
0
0
30
307
0.98
0.01
1.8
3.4
1.26
1.38
mg/l
0.49
24
286
10
106
0.94
0.01
1.0
1.2
—
—
—
0
0
17
164
1.04
0.00
2.8
2.7
7.65
7.12
mmol/l
0.49
17
159
27
264
1.02
0.00
1.1
1.1
—
—
—
0
0
174
1746
1.00
0.00
1.7
1.9
—
—
—
0
0
10
96
1.04
0.00
2.5
2.3
4.19
3.97
mmol/l
—
10
96
10
96
1.04
0.00
2.5
2.3
103.30
105.51
mmol/l
—
10
96
10
96
1.04
0.00
3.3
7.0
6.74
7.16
mmol/l
—
10
77
12
124
0.97
0.00
1.2
1.1
—
—
—
0
0
81
806
1.01
0.00
3.5
2.1
—
—
—
0
0
32
318
1.01
0.00
1.2
1.2
—
—
—
0
0
33
328
1.01
0.00
6.7
4.6
—
—
—
0
0
40
398
1.01
0.00
1.2
1.2
—
—
—
0
0
11
109
1.01
0.00
3.2
3.3
16.60
62.27
u/ml
1.70
11
109
18
179
1.01
0.00
2.8
2.6
1.72
1.49
mmol/l
0.28
18
171
32
319
1.00
0.00
1.5
1.4
313.66
307.91
ug/g
0.05
17
176
82
821
1.00
0.00
3.9
2.1
—
—
—
0
0
82
819
1.00
0.00
3.8
2.1
—
—
—
0
0
1099
10989
1.00
0.00
4.5
4.6
37.49
38.40
mmol/mol
2.80
1015
10415
10
103
0.97
0.00
1.8
2.0
32.90
32.40
pg
—
10
103
55
545
1.01
0.00
1.6
1.6
—
—
—
0
0
15
145
1.03
0.00
1.5
1.5
—
—
—
0
0
15
145
1.03
0.00
3.1
2.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.2
—
197.17
—
0
6
0
5
0.00
-0.00
0.0
6.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.3
—
—
—
0
0
9
99
0.91
-0.00
1.2
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
53
0.94
-0.00
64.0
31.2
8.70
7.37
ug/l
—
5
46
6
62
0.97
-0.00
1.2
1.4
81.00
172.66
mmol/24h
—
6
62
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
8
82
0.98
-0.00
3.0
2.7
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
74
0.95
-0.00
1.3
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint G6_OTHDEMYEL and mortality.

Females

Parameter HR [95% CI] p-value
G6_OTHDEMYEL 2.092 [1.77, 2.47] < 0.001
Birth year 0.994 [0.98, 1.0] 0.142

During the follow-up period (1.1.1998 — 31.12.2019), 246 out of 4099 females with G6_OTHDEMYEL died.

Males

Parameter HR [95% CI] p-value
G6_OTHDEMYEL 2.444 [2.08, 2.87] < 0.001
Birth year 0.983 [0.97, 0.99] < 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 304 out of 2166 males with G6_OTHDEMYEL died.

Mortality risk

Mortality risk for people of age

years, who have G6_OTHDEMYEL.

N-year risk Females Males
1 0.224% 0.37%
5 1.238% 2.478%
10 2.828% 5.803%
15 5.52% 11.151%
20 9.909% 18.746%

Relationships between endpoints

Index endpoint: G6_OTHDEMYEL – Other demyelinating diseases of the central nervous system

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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