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Haemorrhagic and haematological disorders of fetus and newborn

P16_HAEMORRHAGIC_HAEMATOL_DISORD_FETUS_NEWBO

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 P50-P61
  • Cause of death: ICD-10 P50-P61

2 out of 7 registries used, show all original rules.

708

4. Check minimum number of events

None

708

5. Include endpoints

708

6. Filter based on genotype QC (FinnGen only)

661

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
P
Name in latin
Morbositates haemorrhagicae et haematologicae fetus et neonati

Similar endpoints

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 661 353 308
Unadjusted period prevalence (%) 0.13 0.13 0.14
Median age at first event (years) 0.01 0.01 0.01

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
699
Matched controls
6671
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
P59.9
ICD-10 Finland
Neonatal jaundice, unspecified
2801.7
307.7
320
*
P07.3
ICD-10 Finland
Other preterm infants
18.9
256.2
240
180
P59.0
ICD-10 Finland
Neonatal jaundice associated with preterm delivery
+∞
223.0
205
*
Z87.6
ICD-10 Finland
Personal history of certain conditions arising in the perinatal period
9.0
118.1
171
231
P22.0
ICD-10 Finland
Respiratory distress syndrome of newborn
13.5
44.7
44
33
P70.4
ICD-10 Finland
Other neonatal hypoglycaemia
6.1
37.0
69
118
P07.11
ICD-10 Finland
Other low birth weight 1500-1999 g
10.0
32.0
38
38
P59.3
ICD-10 Finland
Neonatal jaundice from breast milk inhibitor
+∞
22.6
22
*
P55.1
ICD-10 Finland
ABO isoimmunization of fetus and newborn
+∞
21.6
21
*
WX722
NOMESCO Finland
PEEP
4.5
21.2
54
121
AA5HE
NOMESCO Finland
Brain ultrasound examination in a child
3.5
21.2
80
239
602
Kela drug reimbursment
Children's severe malnutrition
3.5
19.2
70
204
P07.12
ICD-10 Finland
Other low birth weight 2000-2499 g
5.7
18.7
36
63
P52.0
ICD-10 Finland
Intraventricular (nontraumatic) haemorrhage, grade 1, of fetus and newborn
+∞
18.5
18
*
P07.2
ICD-10 Finland
Extreme immaturity
16.9
18.3
29
17
P52.2
ICD-10 Finland
Intraventricular (nontraumatic) haemorrhage, grade 3, and grade 4 of fetus and newborn
+∞
15.4
15
*
P61.1
ICD-10 Finland
Polycythaemia neonatorum
+∞
15.4
15
*
P61.0
ICD-10 Finland
Transient neonatal thrombocytopenia
+∞
15.4
15
*
P01.5
ICD-10 Finland
Fetus and newborn affected by multiple pregnancy
6.5
14.9
25
38
P22.1
ICD-10 Finland
Transient tachypnoea of newborn
3.7
13.9
45
121
P70.0
ICD-10 Finland
Syndrome of infant of mother with gestational diabetes
4.6
13.2
32
69
P61.4
ICD-10 Finland
Other congenital anaemias, not elsewhere classified
+∞
12.3
12
*
P55.0
ICD-10 Finland
Rh isoimmunization of fetus and newborn
+∞
12.3
12
*
P59.8
ICD-10 Finland
Neonatal jaundice from other specified causes
+∞
12.3
12
*
P27.1
ICD-10 Finland
Bronchopulmonary dysplasia originating in the perinatal period
9.8
12.2
24
24
P07.10
ICD-10 Finland
Other low birth weight 1000-1499 g
11.5
11.0
20
17
Z2446
NOMESCO Finland
Social worker
1.9
10.7
156
868
WX882
NOMESCO Finland
High dependency care
2.1
10.5
106
517
P22.8
ICD-10 Finland
Other respiratory distress of newborn
8.9
10.2
21
23
P00.0
ICD-10 Finland
Fetus and newborn affected by maternal hypertensive disorders
4.8
9.6
22
45
WX730
NOMESCO Finland
Conventional respirator
4.7
9.4
22
46
P05.0
ICD-10 Finland
Light for gestational age
8.2
9.3
20
24
P61.2
ICD-10 Finland
Anaemia of prematurity
+∞
9.2
9
*
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.8
9.0
160
943
R4110
NOMESCO Finland
Physiotherapy
1.7
8.9
193
1205
P05.1
ICD-10 Finland
Small for gestational age
4.1
8.8
24
57
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
8.6
219
1427
A03FA02
ATC
cisapride; oral, rectal
3.2
8.3
33
102
Z3226
NOMESCO Finland
Physiotherapist
1.7
8.2
183
1148
P61.3
ICD-10 Finland
Congenital anaemia from fetal blood loss
+∞
8.2
8
*
P39.9
ICD-10 Finland
Infection specific to the perinatal period, unspecified
4.1
8.1
22
52
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
8.1
194
1241
H35.1
ICD-10 Finland
Retinopathy of prematurity
10.4
8.1
15
14
P36.90
ICD-10 Finland
Suspected bacterial sepsis of newborn
3.8
7.9
24
62
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
2.2
7.6
62
277
WW805
NOMESCO Finland
Transfer from treating institution to lower-Level care, accompanied by paramedic/nurse
10.5
7.6
14
13
P29.30
ICD-10 Finland
Delayed closure of the ductus arteriosus
8.2
7.6
16
19
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
4.0
7.5
21
51
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.7
7.4
153
937
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.7
7.4
161
1001
Z3231
NOMESCO Finland
Registered nurse
1.6
7.2
272
1933
P07.1
ICD-10 Finland
Other low birth weight
12.9
7.2
12
9
AAF20
NOMESCO Finland
Revision of shunt of ventricle of brain
12.9
7.2
12
9
P52.4
ICD-10 Finland
Intracerebral (nontraumatic) haemorrhage of fetus and newborn
+∞
7.2
7
*
Z31.5
ICD-10 Finland
Genetic counselling
2.0
7.0
73
360
P22.9
ICD-10 Finland
Respiratory distress of newborn, unspecified
3.6
7.0
23
63
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.0
6.8
75
377
P01.10
ICD-10 Finland
Fetus and newborn affected by premature rupture of membranes 1-7 days before delivery
4.2
6.8
18
42
F82
ICD-10 Finland
Specific developmental disorder of motor function
2.4
6.7
45
184
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
3.1
6.7
28
89
AA7AA
NOMESCO Finland
Liquor cerebri shunt X-ray examinatin without contrast
9.0
6.6
13
14
F83
ICD-10 Finland
Mixed specific developmental disorders
2.1
6.5
59
276
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.9
6.5
85
454
ZXD20
NOMESCO Finland
Day surgery
2.0
6.3
68
339
J45.8
ICD-10 Finland
Mixed asthma
3.0
6.2
27
88
P52.1
ICD-10 Finland
Intraventricular (nontraumatic) haemorrhage, grade 2, of fetus and newborn
+∞
6.1
6
*
Z2221
NOMESCO Finland
Medical doctor
1.6
6.1
171
1127
Q44.29
ICD-10 Finland
Atresia of bile ducts
8.9
6.1
12
13
JKD50
NOMESCO Finland
Hepatoportoenterostomy
8.9
6.1
12
13
A11JC
ATC
Vitamins, other combinations
5.3
6.1
17
31

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
41
144
2.82
8.27
5.9
4.2
22.80
24.48
umol/l
0.49
41
144
233
1616
1.56
6.79
17.8
8.9
43.45
23.47
umol/l
3.81
221
1472
109
621
1.80
6.76
16.3
7.9
13.71
6.10
umol/l
0.92
101
516
18
59
2.96
4.17
2.5
1.9
—
—
—
0
0
56
328
1.68
3.19
1.6
1.3
—
—
—
0
0
375
3123
1.31
3.18
13.3
11.7
0.00
0.01
e9/l
0.75
295
2358
532
4670
1.36
3.06
12.5
9.2
27.05
25.22
u/l
0.93
515
4511
37
195
1.86
3.02
8.2
6.2
1.23
1.23
mmol/l
0.15
32
177
114
799
1.43
2.93
16.8
14.7
0.82
0.81
mmol/l
0.38
114
770
156
1157
1.37
2.89
3.7
3.0
2.41
2.41
mmol/l
0.16
146
1058
576
5141
1.39
2.82
22.3
16.2
13.50
13.25
%
1.47
566
5050
12
41
2.82
2.63
3.3
3.3
—
—
—
0
0
42
241
1.71
2.62
4.9
3.1
35.71
34.77
umol/l
0.15
42
220
109
777
1.40
2.56
6.5
5.6
1.33
1.88
mg/l
0.87
75
552
57
362
1.55
2.40
1.4
1.4
608.84
20615842.10
pmol/l
0.50
51
325
11
37
2.87
2.35
1.7
2.5
—
—
—
0
0
571
5132
1.34
2.31
11.1
8.1
—
—
—
0
0
384
3290
1.25
2.27
11.9
9.6
47.06
48.33
%
1.11
371
3175
391
3358
1.25
2.26
12.1
9.7
37.52
36.03
%
1.72
376
3240
48
299
1.57
2.21
10.3
5.6
0.10
0.11
%
0.03
20
102
117
869
1.34
2.14
5.5
4.5
—
—
—
0
0
377
3239
1.24
2.12
12.6
10.0
8.26
8.31
%
0.14
358
3109
10
35
2.75
2.08
4.7
1.7
33.10
31.60
pg
—
10
35
27
147
1.78
2.05
2.3
1.9
—
—
—
0
0
8
25
3.08
1.99
1.3
1.4
—
—
—
0
0
49
315
1.52
1.99
2.7
2.4
77.60
80.45
u/ml
—
5
15
373
3217
1.23
1.96
12.4
9.9
3.14
3.31
%
0.62
359
3093
55
364
1.48
1.95
4.1
8.9
0.27
0.45
g/l
0.65
41
305
53
349
1.49
1.93
2.4
1.8
2.41
2.41
mmol/l
0.04
41
289
24
130
1.79
1.87
2.0
1.3
337.33
382.93
ug/g
0.47
15
67
7
21
3.20
1.87
1.6
2.9
61.71
24.19
u/l
—
7
21
46
296
1.52
1.87
9.0
4.8
0.22
0.37
%
0.60
18
119
23
123
1.81
1.87
2.7
2.0
—
—
—
0
0
6
16
3.60
1.85
1.2
1.7
1717.17
1680.44
ml
—
6
16
6
16
3.60
1.85
1.8
2.1
6.68
4.39
mmol/24h
—
6
16
390
3393
1.22
1.84
12.3
10.8
0.22
0.22
e9/l
0.00
339
2858
389
3385
1.22
1.82
11.7
9.7
2.49
2.38
e9/l
0.88
338
2888
364
3150
1.21
1.79
12.5
10.0
0.65
0.62
%
0.47
351
3033
15
70
2.07
1.78
11.7
9.4
—
—
—
0
0
105
792
1.31
1.74
1.9
1.8
—
—
—
0
0
48
318
1.47
1.71
2.8
2.4
—
—
—
0
0
7
23
2.92
1.71
1.7
1.7
—
—
—
0
0
62
432
1.41
1.70
2.1
2.1
176.15
168.98
u/ml
0.05
30
195
46
305
1.47
1.64
10.8
5.6
0.00
0.04
%
0.64
18
113
48
321
1.46
1.64
10.7
5.5
0.33
0.49
%
0.42
21
128
25
144
1.68
1.61
3.1
2.7
—
—
—
0
0
378
3306
1.20
1.59
11.6
9.8
0.60
0.56
e9/l
1.43
318
2731
158
1271
1.24
1.57
16.2
9.8
—
—
—
0
0
7
25
2.69
1.56
1.1
1.2
—
—
—
0
0
398
3502
1.20
1.55
14.7
11.5
3.33
3.39
e9/l
0.17
332
2890
16
81
1.91
1.55
1.9
1.7
—
—
—
0
0
377
3305
1.19
1.52
11.7
9.8
0.04
0.04
e9/l
1.66
317
2731
172
1402
1.23
1.51
3.5
3.5
3.01
2.68
mg/l
0.55
155
1267
316
2730
1.19
1.50
12.2
8.6
5.88
5.97
mmol/l
0.18
297
2585
7
26
2.58
1.49
1.1
1.2
—
—
—
0
0
80
595
1.32
1.48
7.9
5.0
76.27
62.01
e9/l
1.17
57
361
23
133
1.67
1.48
5.3
4.4
—
—
—
0
0
18
97
1.79
1.46
4.3
4.0
1.54
4.49
%
—
8
39
150
1210
1.23
1.45
3.4
5.2
7.82
8.65
mmol/l
0.94
145
1157
7
27
2.49
1.43
1.0
1.1
—
—
—
0
0
93
712
1.28
1.40
2.0
1.7
—
—
—
0
0
354
3101
1.18
1.40
13.6
10.5
—
—
—
0
0
647
6009
1.37
1.39
22.5
16.4
6.90
6.94
e9/l
0.09
621
5652
10
44
2.19
1.38
1.4
1.3
—
—
—
0
0
18
99
1.75
1.38
8.1
7.8
5.01
4.86
kpa
0.28
18
99
18
99
1.75
1.38
8.1
7.8
1.76
1.59
mmol/l
—
9
49
18
99
1.75
1.38
8.1
7.4
10.06
9.17
kpa
1.09
18
99
311
2699
1.18
1.37
9.0
5.6
147.89
133.40
u/l
1.58
296
2541
234
1982
1.19
1.37
10.0
9.4
—
—
—
0
0
137
1102
1.23
1.36
5.1
3.8
—
—
—
0
0
141
1138
1.23
1.36
4.1
3.6
585.46
605.55
mosm/kgh2o
0.39
123
995
15
79
1.83
1.32
9.5
3.2
24.77
23.03
mmol/l
0.71
15
74
158
1294
1.21
1.32
15.3
12.1
1.39
1.36
mmol/l
0.58
153
1240
141
1144
1.22
1.29
5.0
3.7
6.61
6.43
e6/l
0.05
126
1018
92
712
1.27
1.29
2.1
1.9
—
—
—
0
0
47
330
1.39
1.28
1.7
1.5
—
—
—
0
0
15
80
1.81
1.28
1.1
1.1
—
—
—
0
0
14
73
1.85
1.27
7.4
2.4
—
—
—
0
0
6
24
2.40
1.23
1.7
1.1
—
—
—
0
0
173
1443
1.19
1.19
17.3
9.9
7.41
7.41
ph
—
6
45
173
1443
1.19
1.19
17.2
9.9
5.09
5.00
kpa
0.91
165
1399
39
269
1.41
1.19
1.9
1.9
—
—
—
0
0
644
5995
1.32
1.18
22.7
16.5
272.66
273.19
e9/l
0.07
620
5648
644
5997
1.32
1.16
22.5
16.4
85.78
85.59
fl
0.39
636
5891
0
35
0.00
1.13
0.0
1.2
—
—
—
0
0
13
69
1.81
1.13
1.7
1.2
—
—
—
0
0
22
136
1.56
1.13
15.6
5.9
—
—
—
0
0
152
1259
1.19
1.13
5.7
3.9
—
—
—
0
0
644
6000
1.31
1.13
22.5
16.3
28.87
28.78
pg
0.45
636
5897
644
6001
1.31
1.12
22.6
16.4
4.62
4.62
e12/l
0.02
615
5636
289
2525
1.16
1.11
21.5
14.7
1.23
1.23
mmol/l
0.16
277
2427
87
685
1.24
1.07
1.2
1.2
—
56.79
—
0
7
48
350
1.33
1.06
1.0
1.0
8.94
8.83
mu/l
0.04
41
304
45
325
1.34
1.06
5.3
3.8
—
—
—
0
0
644
6006
1.30
1.06
23.3
16.8
133.06
132.48
g/l
0.42
638
5905
643
5996
1.29
1.06
24.3
17.6
39.58
39.38
%
0.52
626
5741
18
108
1.61
1.05
8.1
7.4
7.40
7.40
ph
0.02
18
101
236
2039
1.16
1.05
4.6
3.8
69.38
68.06
nmol/l
0.34
221
1938
12
64
1.80
1.04
1.0
1.0
—
—
—
0
0
131
1082
1.19
1.01
5.3
5.8
1.09
1.10
inr
0.15
39
280
206
1770
1.16
0.98
5.7
4.8
20.06
25.24
e6/l
0.28
154
1341
30
206
1.41
0.97
5.5
4.5
—
—
—
0
0
0
30
0.00
0.96
0.0
1.0
—
—
—
0
0
194
1662
1.16
0.96
5.1
3.7
—
—
—
0
0
90
722
1.22
0.95
1.5
1.5
233.24
360.64
u/ml
0.76
80
683
6
115
0.49
0.94
1.3
2.0
—
—
—
0
0
6
26
2.21
0.93
5.7
2.8
3.82
3.83
mmol/l
—
6
26
129
1073
1.18
0.93
1.2
1.2
—
—
—
0
0
6
27
2.13
0.91
1.0
1.1
—
—
—
0
0
33
234
1.36
0.90
1.5
1.6
—
—
—
0
0
18
253
0.67
0.89
1.1
1.0
—
—
—
0
0
12
68
1.70
0.88
1.5
1.4
—
—
—
0
0
12
68
1.70
0.88
1.5
1.4
—
—
—
0
0
12
68
1.70
0.88
2.2
1.8
—
—
—
0
0
72
570
1.23
0.87
1.5
1.4
22.99
18.52
nmol/l
1.55
58
504
182
1564
1.15
0.86
1.6
1.5
—
—
—
0
0
12
69
1.67
0.84
1.5
1.4
—
—
—
0
0
21
139
1.46
0.83
4.7
3.9
—
—
—
0
0
232
2033
1.13
0.82
6.6
5.7
77.17
51.41
e6/l
0.34
160
1383
20
132
1.46
0.81
7.4
5.7
—
—
—
0
0
293
2607
1.13
0.81
19.3
13.6
1.23
1.23
mmol/l
0.19
269
2439
14
85
1.58
0.81
1.1
1.1
—
—
—
0
0
0
25
0.00
0.78
0.0
2.0
—
1.18
—
0
17
10
56
1.71
0.77
1.8
1.5
—
—
—
0
0
151
1294
1.14
0.75
14.6
11.9
—
—
—
0
0
39
466
0.79
0.73
1.2
1.1
2.26
9.39
u/ml
—
9
120
7
37
1.81
0.73
1.0
1.1
—
—
—
0
0
5
24
2.00
0.72
13.4
3.4
108.00
106.11
mmol/l
—
5
19
5
24
2.00
0.72
13.4
3.4
10.60
11.63
mmol/l
—
5
19
11
163
0.64
0.72
1.9
1.3
—
—
—
0
0
318
2861
1.11
0.70
4.8
3.9
575.18
207.48
e6/l
0.27
11
25
9
56
1.54
0.69
19.1
8.4
1.27
1.22
mmol/l
—
9
51
9
56
1.54
0.69
8.7
2.8
1.07
1.31
mmol/l
—
9
49
192
1681
1.12
0.69
5.4
4.6
0.68
0.18
e6/l
0.68
139
1262
16
105
1.46
0.68
5.6
3.3
17.16
17.89
%
0.46
11
70
5
88
0.54
0.67
4.4
2.4
—
—
—
0
0
61
490
1.21
0.67
13.3
14.2
106.64
105.81
mmol/l
0.93
61
490
56
446
1.22
0.67
2.5
2.3
5.62
7.83
iu/l
0.77
36
283
7
41
1.64
0.67
1.0
1.2
210.00
259.24
iu/ml
—
7
41
113
958
1.15
0.66
4.4
3.0
—
—
—
0
0
563
5235
1.14
0.65
16.4
11.3
24.39
23.75
mg/l
0.15
375
3472
7
42
1.60
0.65
1.1
1.0
—
78.50
—
0
8
130
1115
1.14
0.65
4.0
4.1
2.87
2.77
e6/l
0.05
77
643
192
1688
1.12
0.64
5.4
4.5
—
—
—
0
0
8
125
0.61
0.64
1.8
1.7
—
—
—
0
0
18
123
1.41
0.64
3.4
3.7
3.49
3.27
e9/l
0.22
18
123
107
907
1.15
0.63
4.7
3.1
61.96
56.28
u/l
0.18
101
845
61
495
1.19
0.62
2.6
2.3
4.91
5.67
u/l
0.42
39
297
11
68
1.55
0.61
1.0
1.3
—
—
—
0
0
0
22
0.00
0.58
0.0
2.7
—
—
—
0
0
29
218
1.28
0.58
5.7
4.4
40.05
6.21
e6/l
0.42
22
155
153
1336
1.12
0.58
12.0
10.0
23.56
23.50
mmol/l
0.12
153
1336
357
3254
1.10
0.58
5.3
4.6
7.18
7.06
mm/h
0.08
329
3030
29
219
1.28
0.56
5.7
4.4
347.86
936.14
e6/l
0.49
22
162
90
761
1.15
0.56
3.5
2.9
322.99
335.82
nmol/l
0.28
85
734
49
394
1.20
0.56
2.6
2.6
35.52
26.86
u/l
0.28
42
322
15
102
1.41
0.55
1.3
1.4
—
—
—
0
0
327
2974
1.09
0.55
4.9
4.4
—
—
—
0
0
18
127
1.36
0.55
4.7
4.0
50.39
50.25
%
0.01
18
127
11
152
0.69
0.55
1.4
2.1
—
—
—
0
0
9
58
1.49
0.54
1.0
1.3
—
—
—
0
0
47
378
1.20
0.54
2.6
2.2
7.96
8.23
nmol/l
0.07
42
331
6
37
1.55
0.53
1.0
1.1
—
—
—
0
0
6
38
1.51
0.52
1.5
1.3
—
—
—
0
0
15
104
1.38
0.51
2.5
2.8
—
—
—
0
0
44
495
0.84
0.51
1.2
1.2
10.03
16.62
iu/ml
1.44
11
91
26
197
1.27
0.50
4.9
3.6
13.65
8.99
%
0.64
26
197
26
197
1.27
0.50
5.0
3.6
68.81
65.21
%
0.43
26
197
267
2416
1.09
0.49
3.5
2.7
1.10
1.08
mmol/l
0.19
253
2284
126
1100
1.11
0.49
4.0
3.9
0.77
0.87
e6/l
0.22
71
626
7
43
1.56
0.49
1.0
1.1
317.29
276.79
mg/l
—
7
43
7
44
1.52
0.48
1.4
1.5
—
—
—
0
0
7
44
1.52
0.48
1.4
1.5
—
—
—
0
0
7
44
1.52
0.48
1.4
1.5
—
—
—
0
0
25
190
1.27
0.48
4.6
9.7
24.95
23.91
mmol/l
0.97
25
179
7
45
1.49
0.47
8.3
7.3
—
—
—
0
0
37
295
1.21
0.47
24.1
16.5
16.09
16.02
kpa
0.02
37
285
16
114
1.35
0.47
1.1
1.1
—
—
—
0
0
24
182
1.27
0.47
5.6
5.0
—
—
—
0
0
54
447
1.17
0.46
1.6
1.9
—
—
—
0
0
37
296
1.20
0.46
24.1
16.5
5.21
5.36
kpa
0.45
37
286
34
270
1.21
0.45
1.0
1.0
2.98
3.24
kpa
0.58
28
224
13
167
0.74
0.45
1.5
1.8
—
—
—
0
0
277
2767
0.93
0.44
2.5
2.2
5.25
5.29
mmol/l
0.22
244
2522
54
588
0.87
0.43
4.0
3.9
534.47
1469.87
ng/l
1.81
30
339
26
202
1.24
0.43
4.9
3.6
1.83
1.44
e9/l
0.58
21
147
107
934
1.11
0.43
1.6
1.7
—
—
—
0
0
130
1148
1.10
0.42
3.2
3.5
76.04
103.35
ug/g
0.96
108
896
130
1148
1.10
0.42
3.0
2.5
—
—
—
0
0
18
134
1.29
0.41
1.1
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
0
16
0.00
0.41
0.0
1.8
—
22.02
—
0
11
34
274
1.19
0.40
1.0
1.0
-1.88
-2.39
mmol/l
—
8
69
34
274
1.19
0.40
1.0
1.0
7.54
7.34
kpa
0.27
28
227
34
274
1.19
0.40
1.0
1.0
—
—
—
0
0
24
187
1.23
0.39
4.5
3.6
28.96
24.89
%
0.48
24
187
0
18
0.00
0.39
0.0
2.0
—
—
—
0
0
60
510
1.13
0.38
2.5
2.7
—
—
—
0
0
280
2564
1.07
0.37
4.3
3.4
54.52
51.32
ug/l
0.19
264
2436
158
1416
1.08
0.37
12.4
10.9
0.91
1.09
mmol/l
0.32
138
1119
9
66
1.31
0.37
1.9
1.9
—
—
—
0
0
31
347
0.85
0.36
1.2
1.1
9.41
7.10
u/ml
0.17
18
226
115
1018
1.09
0.36
6.8
4.0
7.38
7.39
ph
0.33
28
159
10
69
1.39
0.36
1.1
1.1
156.60
185.11
mg/l
—
10
64
153
1372
1.08
0.36
12.5
10.7
5.10
5.17
kpa
0.20
153
1338
31
252
1.18
0.35
3.6
7.3
173.46
232.44
ng/l
0.35
26
233
158
1421
1.08
0.34
12.5
10.9
5.70
5.80
kpa
0.98
158
1383
32
262
1.17
0.33
1.7
1.5
—
—
—
0
0
125
1274
0.92
0.33
3.0
3.4
—
—
—
0
0
60
518
1.12
0.31
2.7
2.4
2326.40
7900.51
u/l
—
9
128
7
94
0.71
0.31
1.0
1.3
—
—
—
0
0
25
202
1.19
0.31
4.7
3.6
471.67
373.16
e6/l
0.29
18
133
18
208
0.82
0.30
1.7
4.2
—
—
—
0
0
493
4617
1.06
0.30
20.6
13.8
3.96
3.94
mmol/l
0.59
476
4457
59
510
1.11
0.30
2.5
1.9
—
—
—
0
0
23
259
0.84
0.30
1.1
1.2
—
—
—
0
0
236
2165
1.06
0.29
10.2
4.9
40.49
26.34
u/l
1.91
225
2082
12
89
1.29
0.29
2.2
2.3
—
—
—
0
0
202
1846
1.06
0.28
2.5
2.0
—
—
—
0
0
29
240
1.16
0.28
1.3
1.1
5.37
14.80
u/ml
—
6
30
43
367
1.13
0.28
6.3
4.6
21.58
24.02
nmol/l
0.43
43
361
9
112
0.76
0.27
1.1
1.3
13.19
15.31
u/ml
—
9
102
9
113
0.76
0.27
1.1
1.6
—
—
—
0
0
24
196
1.17
0.27
4.5
3.6
757.39
526.51
e6/l
0.89
18
140
52
546
0.90
0.27
1.2
1.2
9.53
3.31
u/ml
1.25
38
408
184
1680
1.06
0.27
2.0
1.8
—
—
—
0
0
13
99
1.26
0.27
1.1
1.2
—
—
—
0
0
25
206
1.16
0.26
1.4
1.2
—
—
—
0
0
79
809
0.92
0.25
1.5
1.8
—
—
—
0
0
10
74
1.29
0.25
1.5
1.1
—
—
—
0
0
10
74
1.29
0.25
1.1
1.0
—
—
—
0
0
9
72
1.20
0.25
3.2
4.7
26.91
25.72
ug/l
—
9
72
24
198
1.16
0.24
4.5
3.6
0.23
0.19
e9/l
0.32
18
141
26
216
1.15
0.24
31.3
21.5
0.79
0.75
%
0.23
26
216
25
207
1.16
0.24
1.4
1.2
—
—
—
0
0
19
212
0.85
0.23
1.6
2.1
—
—
—
0
0
13
101
1.23
0.23
4.8
8.4
—
—
—
0
0
5
37
1.29
0.23
3.0
5.9
202.60
232.32
ug/l
—
5
37
93
942
0.93
0.23
1.8
1.6
—
—
—
0
0
29
245
1.14
0.22
1.6
1.4
1.64
2.93
u/ml
0.65
18
180
5
38
1.26
0.22
4.6
2.9
1043.20
1339.00
u/ml
—
5
38
5
38
1.26
0.22
3.8
2.5
30.62
18.22
umol/l
—
5
38
5
39
1.23
0.22
1.4
1.0
—
—
—
0
0
109
987
1.06
0.21
4.5
3.6
0.00
0.00
estimate
-0.00
44
334
5
40
1.19
0.21
1.0
1.8
196.80
147.22
pmol/l
—
5
40
0
10
0.00
0.21
0.0
13.7
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
2.6
—
—
—
0
0
137
1365
0.95
0.20
2.0
2.1
—
—
—
0
0
0
13
0.00
0.20
0.0
7.8
—
—
—
0
0
12
138
0.83
0.20
41.4
26.0
10.43
11.49
%
0.60
12
138
6
46
1.25
0.20
1.0
1.2
—
—
—
0
0
6
49
1.17
0.19
1.7
1.8
—
—
—
0
0
34
294
1.11
0.19
1.9
1.8
—
—
—
0
0
87
787
1.06
0.18
1.8
1.9
1.18
1.24
mmol/l
0.19
81
733
195
1805
1.04
0.18
3.4
3.3
6.21
6.32
ph
0.25
21
208
25
214
1.12
0.17
1.2
1.2
—
—
—
0
0
5
66
0.72
0.17
1.4
1.1
—
—
—
0
0
33
344
0.91
0.17
1.7
1.4
—
—
—
0
0
28
294
0.91
0.16
1.1
1.1
1.82
0.41
u/ml
0.35
14
141
407
3827
1.04
0.16
4.0
3.2
14.26
14.39
pmol/l
0.59
369
3439
59
598
0.94
0.16
1.3
1.3
3.51
3.29
u/ml
0.05
43
429
33
343
0.91
0.16
1.7
2.4
—
—
—
0
0
8
69
1.11
0.16
4.6
3.1
—
—
—
0
0
25
216
1.11
0.15
1.2
1.1
8.62
5.94
iu/ml
—
5
31
69
691
0.95
0.13
1.5
1.9
—
—
—
0
0
22
190
1.11
0.13
28.6
20.4
—
—
—
0
0
21
181
1.11
0.13
1.3
1.1
25.45
6.04
u/ml
—
6
49
271
2539
1.03
0.13
3.3
2.8
2.54
2.57
mmol/l
0.23
253
2377
11
90
1.17
0.12
1.1
1.3
13.40
3.47
u/ml
—
5
53
70
698
0.95
0.12
1.5
1.9
—
—
—
0
0
251
2439
0.97
0.12
1.9
1.9
2.78
3.64
u/ml
0.42
43
425
31
318
0.93
0.12
1.1
1.1
4.84
10.47
u/ml
0.93
17
198
26
229
1.09
0.11
1.6
1.5
16.74
14.06
u/ml
0.06
17
162
489
4627
1.03
0.11
20.7
13.8
139.48
139.40
mmol/l
0.37
472
4493
24
211
1.09
0.11
22.6
14.5
113.83
122.90
g/l
1.19
24
206
15
128
1.12
0.10
2.2
1.6
—
—
—
0
0
70
695
0.96
0.10
1.5
1.9
—
—
—
0
0
31
316
0.93
0.10
1.4
1.1
—
—
—
0
0
43
389
1.06
0.10
1.7
1.4
—
—
—
0
0
451
4267
1.02
0.10
4.1
3.6
2.12
2.04
mu/l
0.68
420
4007
27
240
1.08
0.10
1.4
1.6
1418.56
1079.37
nmol/l
0.95
20
179
30
305
0.94
0.09
1.1
1.4
—
—
—
0
0
222
2084
1.02
0.09
4.0
3.5
0.00
0.00
estimate
-0.00
44
345
20
207
0.92
0.09
1.1
1.3
140.56
219.37
miu/ml
—
10
85
25
223
1.07
0.08
1.1
1.1
—
—
—
0
0
6
56
1.02
0.08
1.3
1.2
—
—
—
0
0
10
84
1.14
0.08
1.2
1.1
—
—
—
0
0
75
738
0.97
0.08
1.7
1.6
—
—
—
0
0
34
308
1.06
0.08
19.9
17.0
122.76
126.72
g/l
0.49
34
299
57
564
0.96
0.07
1.2
1.2
5.87
6.36
u/ml
0.11
40
423
240
2321
0.98
0.07
4.1
3.1
35.32
36.10
mmol/mol
0.54
220
2185
109
1016
1.03
0.07
2.9
3.0
1.02
1.02
kg/l
0.29
22
194
6
69
0.83
0.07
1.0
1.1
—
—
—
0
0
6
70
0.82
0.07
1.5
2.8
8.83
122.02
u/ml
—
6
57
28
252
1.06
0.07
1.3
1.2
—
—
—
0
0
100
978
0.97
0.07
1.7
1.5
90.35
98.05
pmol/l
0.78
54
517
11
117
0.90
0.07
1.2
1.2
—
—
—
0
0
17
150
1.08
0.07
1.6
1.3
—
—
—
0
0
70
687
0.97
0.06
1.5
1.9
—
—
—
0
0
9
96
0.89
0.06
1.0
1.1
—
—
—
0
0
220
2074
1.02
0.06
5.8
5.2
0.00
0.00
estimate
-0.00
44
355
26
235
1.06
0.06
27.9
8.0
22.87
22.96
mmol/l
0.08
26
227
48
474
0.96
0.06
1.4
1.3
158.29
167.46
iu/ml
0.06
18
132
267
2523
1.02
0.06
3.3
2.7
1.32
1.39
mmol/l
2.34
249
2374
18
182
0.94
0.04
1.4
1.2
—
—
—
0
0
18
163
1.06
0.03
1.1
1.1
—
—
—
0
0
11
97
1.08
0.03
1.1
1.5
—
238.57
—
0
7
274
2599
1.01
0.03
3.5
2.9
4.15
4.24
mmol/l
0.84
255
2469
242
2325
0.99
0.03
1.8
1.7
1.43
1.46
g/l
0.13
115
1164
67
651
0.98
0.03
1.5
1.9
—
—
—
0
0
51
476
1.02
0.03
1.3
2.4
—
—
—
0
0
71
666
1.02
0.03
2.0
1.6
380.00
583.93
titre
—
8
107
18
179
0.96
0.02
6.1
5.5
—
—
—
0
0
11
111
0.94
0.01
4.2
4.5
—
—
—
0
0
11
99
1.06
0.01
1.7
1.6
—
—
—
0
0
22
204
1.03
0.01
3.4
3.6
—
—
—
0
0
219
2083
1.00
0.01
4.1
3.6
0.00
0.00
estimate
-0.00
45
346
14
128
1.04
0.00
2.4
1.8
111.04
138.20
ng/l
1.32
14
120
36
338
1.02
0.00
1.2
1.1
—
19.42
—
0
5
62
597
0.99
0.00
2.7
2.4
12.38
52.54
ng/l
1.74
30
211
15
145
0.99
0.00
6.2
5.8
3.71
2.03
ug/l
1.34
15
145
12
112
1.02
0.00
1.6
1.2
—
0.20
—
0
6
85
811
1.00
0.00
1.5
1.4
113.00
250.84
titre
—
5
31
18
175
0.98
0.00
1.3
1.2
—
—
—
0
0
15
144
0.99
0.00
1.3
1.4
—
—
—
0
0
25
242
0.99
0.00
1.1
1.1
—
—
—
0
0
13
129
0.96
0.00
1.6
1.4
—
—
—
0
0
21
198
1.01
0.00
37.3
19.9
—
—
—
0
0
27
260
0.99
0.00
19.5
17.1
0.60
0.64
%
0.24
27
260
58
555
1.00
0.00
1.5
2.0
—
—
—
0
0
42
397
1.01
0.00
3.8
4.4
3.77
44.65
mg/mmol
0.63
37
324
19
182
1.00
0.00
27.7
21.4
72.09
71.12
%
0.09
19
182
10
100
0.95
0.00
4.4
4.9
—
—
—
0
0
58
553
1.00
0.00
1.2
1.2
1.00
1.15
u/ml
0.10
39
396
14
132
1.01
0.00
2.4
2.5
1.35
2.09
mmol/l
—
9
105
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
7.4
—
—
—
0
0
0
5
0.00
0.00
0.0
4.0
—
6.92
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
6
64
0.89
-0.00
3.2
6.9
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
232.50
—
0
6
0
6
0.00
-0.00
0.0
2.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
9
85
1.01
-0.00
1.1
1.1
—
—
—
0
0
5
55
0.87
-0.00
1.2
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.2
—
—
—
0
0
5
53
0.90
-0.00
26.0
3.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
6
62
0.92
-0.00
5.5
2.4
3.00
1.61
ug/l
—
6
56
0
6
0.00
-0.00
0.0
2.2
—
1492.67
—
0
6
0
6
0.00
-0.00
0.0
2.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: P16_HAEMORRHAGIC_HAEMATOL_DISORD_FETUS_NEWBO – Haemorrhagic and haematological disorders of fetus and newborn

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).