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Haemorrhagic and haematological disorders of fetus and newborn

P16_HAEMORRHAGIC_HAEMATOL_DISORD_FETUS_NEWBO

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 P50-P61
  • Cause of death: ICD-10 P50-P61

2 out of 7 registries used, show all original rules.

708

4. Check minimum number of events

None

708

5. Include endpoints

708

6. Filter based on genotype QC (FinnGen only)

708

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
P
Name in latin
Morbositates haemorrhagicae et haematologicae fetus et neonati

Similar endpoints

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 708 379 329
Unadjusted period prevalence (%) 0.14 0.13 0.15
Median age at first event (years) 0.01 0.01 0.01

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
613
Matched controls
5832
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
P59.9
ICD-10 Finland
Neonatal jaundice, unspecified
2485.5
315.9
283
*
P59.0
ICD-10 Finland
Neonatal jaundice associated with preterm delivery
+∞
186.3
172
*
P07.3
ICD-10 Finland
Other preterm infants
19.1
124.2
202
146
Z87.6
ICD-10 Finland
Personal history of certain conditions arising in the perinatal period
8.4
60.8
147
212
P22.0
ICD-10 Finland
Respiratory distress syndrome of newborn
13.9
20.9
36
26
P70.4
ICD-10 Finland
Other neonatal hypoglycaemia
6.2
20.8
58
97
P07.11
ICD-10 Finland
Other low birth weight 1500-1999 g
13.5
20.1
35
26
P59.3
ICD-10 Finland
Neonatal jaundice from breast milk inhibitor
+∞
19.5
19
*
P55.1
ICD-10 Finland
ABO isoimmunization of fetus and newborn
+∞
19.5
19
*
P52.0
ICD-10 Finland
Intraventricular (nontraumatic) haemorrhage, grade 1, of fetus and newborn
+∞
16.4
16
*
P07.2
ICD-10 Finland
Extreme immaturity
13.7
14.7
25
18
AA5HE
NOMESCO Finland
Brain ultrasound examination in a child
3.4
14.3
71
214
P52.2
ICD-10 Finland
Intraventricular (nontraumatic) haemorrhage, grade 3, and grade 4 of fetus and newborn
+∞
13.3
13
*
P61.1
ICD-10 Finland
Polycythaemia neonatorum
+∞
13.3
13
*
P61.0
ICD-10 Finland
Transient neonatal thrombocytopenia
+∞
13.3
13
*
602
Kela drug reimbursment
Children's severe malnutrition
3.5
13.1
62
180
P61.4
ICD-10 Finland
Other congenital anaemias, not elsewhere classified
+∞
12.3
12
*
P55.0
ICD-10 Finland
Rh isoimmunization of fetus and newborn
+∞
12.3
12
*
WX722
NOMESCO Finland
PEEP
4.4
12.3
45
104
P59.8
ICD-10 Finland
Neonatal jaundice from other specified causes
+∞
11.3
11
*
P27.1
ICD-10 Finland
Bronchopulmonary dysplasia originating in the perinatal period
10.3
11.0
21
20
P07.10
ICD-10 Finland
Other low birth weight 1000-1499 g
13.8
10.2
17
12
WX882
NOMESCO Finland
High dependency care
2.3
10.2
102
469
P22.8
ICD-10 Finland
Other respiratory distress of newborn
9.3
10.0
20
21
P01.5
ICD-10 Finland
Fetus and newborn affected by multiple pregnancy
8.5
9.5
20
23
P22.1
ICD-10 Finland
Transient tachypnoea of newborn
3.6
8.4
37
103
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
8.3
208
1336
P07.1
ICD-10 Finland
Other low birth weight
19.4
8.3
12
6
P00.0
ICD-10 Finland
Fetus and newborn affected by maternal hypertensive disorders
6.7
8.3
20
29
P61.2
ICD-10 Finland
Anaemia of prematurity
+∞
8.2
8
*
AA7AA
NOMESCO Finland
Liquor cerebri shunt X-ray examinatin without contrast
14.0
8.0
13
9
P70.0
ICD-10 Finland
Syndrome of infant of mother with gestational diabetes
4.5
8.0
27
59
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.8
7.9
143
830
R4110
NOMESCO Finland
Physiotherapy
1.7
7.4
166
1026
P61.3
ICD-10 Finland
Congenital anaemia from fetal blood loss
+∞
7.2
7
*
P29.30
ICD-10 Finland
Delayed closure of the ductus arteriosus
7.4
7.1
16
21
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.2
7.1
77
364
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.8
7.0
133
779
JKD50
NOMESCO Finland
Hepatoportoenterostomy
13.3
6.7
11
8
AAF20
NOMESCO Finland
Revision of shunt of ventricle of brain
13.3
6.7
11
8
Q44.29
ICD-10 Finland
Atresia of bile ducts
13.3
6.7
11
8
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
5.0
6.7
20
39
H35.1
ICD-10 Finland
Retinopathy of prematurity
9.0
6.6
13
14
WW805
NOMESCO Finland
Transfer from treating institution to lower-Level care, accompanied by paramedic/nurse
9.0
6.6
13
14
G80.1
ICD-10 Finland
Spastic diplegic cerebral palsy
11.8
6.4
11
9
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
9.7
6.3
12
12

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
41
144
2.82
8.27
5.9
4.2
22.8
24.5
umol/l
0.49
41
144
109
618
1.81
6.87
16.3
7.9
13.7
6.1
umol/l
0.91
101
514
232
1613
1.56
6.67
17.9
8.9
43.6
23.5
umol/l
3.81
220
1466
34
130
2.57
5.88
4.4
5.9
76.8
16.6
u/ml
0.85
34
123
18
59
2.96
4.17
2.5
1.9
—
—
—
0
0
375
3118
1.32
3.24
13.3
11.7
0.0
0.0
e9/l
0.75
295
2353
56
328
1.68
3.19
1.6
1.3
—
—
—
0
0
37
193
1.88
3.10
8.2
6.2
1.2
1.2
mmol/l
0.18
32
175
114
797
1.44
2.97
16.8
14.7
0.8
0.8
mmol/l
0.47
114
764
531
4668
1.36
2.96
12.5
9.2
27.0
25.2
u/l
0.91
514
4509
156
1153
1.37
2.95
3.7
3.0
2.4
2.4
mmol/l
0.19
146
1050
574
5126
1.38
2.75
22.1
16.1
13.3
13.1
%
2.46
563
5033
42
240
1.71
2.65
4.9
3.1
35.7
35.1
umol/l
0.10
42
215
12
41
2.82
2.63
3.3
3.3
—
—
—
0
0
57
356
1.57
2.56
1.4
1.4
608.8
21003592.6
pmol/l
0.50
51
319
11
37
2.87
2.48
1.7
2.5
—
—
—
0
0
108
773
1.39
2.48
6.6
5.7
1.3
1.9
mg/l
0.87
75
550
48
295
1.59
2.33
10.3
5.6
0.0
0.1
%
0.49
14
84
311
2598
1.26
2.31
12.3
10.5
—
—
—
0
0
571
5135
1.33
2.28
11.1
8.1
—
—
—
0
0
34
193
1.72
2.23
2.7
2.2
—
—
—
0
0
34
193
1.72
2.23
2.7
2.2
—
—
—
0
0
34
193
1.72
2.23
2.7
2.2
—
—
—
0
0
34
193
1.72
2.23
2.7
2.2
—
—
—
0
0
10
34
2.83
2.22
4.7
1.8
33.1
31.5
pg
—
10
34
117
864
1.35
2.22
5.5
4.5
—
—
—
0
0
390
3354
1.25
2.21
12.1
9.7
37.6
36.1
%
1.74
374
3228
383
3288
1.25
2.20
11.9
9.6
47.0
48.3
%
1.11
370
3169
376
3236
1.24
2.05
12.6
9.9
8.3
8.3
%
0.08
357
3105
27
147
1.78
2.05
2.3
1.9
—
—
—
0
0
53
345
1.50
2.02
2.4
1.8
2.4
2.4
mmol/l
0.04
41
285
55
361
1.49
2.02
4.1
8.9
0.3
0.5
g/l
0.66
41
303
49
314
1.53
2.01
2.7
2.4
77.6
80.4
u/ml
—
5
15
8
25
3.08
1.99
1.3
1.4
—
—
—
0
0
46
292
1.54
1.97
9.0
4.9
0.2
0.4
%
0.76
12
73
24
129
1.80
1.91
2.0
1.3
337.3
386.3
ug/g
0.52
15
66
372
3213
1.22
1.91
12.4
9.9
3.1
3.3
%
0.65
358
3085
390
3389
1.22
1.87
12.3
10.8
0.2
0.2
e9/l
0.01
339
2853
23
123
1.81
1.87
2.7
2.0
—
—
—
0
0
6
16
3.60
1.85
1.8
1.8
—
—
—
0
0
364
3147
1.22
1.82
12.5
10.0
0.6
0.6
%
0.48
351
3030
15
70
2.07
1.78
11.7
9.4
—
—
—
0
0
388
3381
1.21
1.77
11.7
9.7
2.5
2.4
e9/l
0.91
337
2877
62
429
1.42
1.76
2.1
2.1
176.1
170.7
u/ml
0.04
30
194
105
791
1.31
1.76
1.9
1.8
—
—
—
0
0
48
317
1.48
1.74
2.8
2.4
—
—
—
0
0
46
302
1.49
1.72
10.8
5.6
0.0
0.1
%
0.64
14
96
48
318
1.47
1.71
10.7
5.5
0.2
0.5
%
1.26
15
103
25
143
1.69
1.65
3.1
2.7
—
—
—
0
0
398
3498
1.20
1.59
14.7
11.5
3.3
3.4
e9/l
0.15
332
2885
7
25
2.69
1.56
1.1
1.2
—
—
—
0
0
158
1272
1.24
1.55
16.2
9.8
—
—
—
0
0
16
81
1.91
1.55
1.9
1.7
—
—
—
0
0
377
3302
1.19
1.55
11.7
9.8
0.6
0.6
e9/l
1.48
317
2726
377
3302
1.19
1.55
11.7
9.8
0.0
0.0
e9/l
1.67
317
2727
172
1399
1.23
1.54
3.5
3.6
3.0
2.7
mg/l
0.56
155
1265
23
132
1.69
1.51
5.3
4.4
—
—
—
0
0
80
594
1.32
1.50
7.9
5.1
76.3
61.9
e9/l
1.19
57
361
7
26
2.58
1.49
1.1
1.2
—
—
—
0
0
93
707
1.29
1.47
2.0
1.7
—
—
—
0
0
150
1210
1.23
1.45
3.4
5.2
7.8
8.7
mmol/l
0.96
145
1151
141
1130
1.24
1.45
4.1
3.6
582.8
608.0
mosm/kgh2o
0.53
123
988
315
2727
1.19
1.45
12.2
8.6
5.9
6.0
mmol/l
0.16
296
2581
7
27
2.49
1.43
1.0
1.1
—
—
—
0
0
18
98
1.77
1.42
8.1
7.4
10.1
9.2
kpa
1.06
18
98
18
98
1.77
1.42
4.3
4.0
1.5
4.5
%
—
8
39
18
98
1.77
1.42
8.1
7.8
1.8
1.6
mmol/l
—
9
48
18
98
1.77
1.42
8.1
7.8
5.0
4.9
kpa
0.29
18
98
10
44
2.19
1.38
1.4
1.3
—
—
—
0
0
137
1100
1.23
1.38
5.1
3.8
—
—
—
0
0
234
1981
1.19
1.37
10.0
9.4
—
—
—
0
0
647
6011
1.37
1.37
22.5
16.3
6.9
6.9
e9/l
0.08
621
5655
47
326
1.40
1.36
1.7
1.5
—
—
—
0
0
310
2695
1.18
1.32
9.0
5.6
147.9
133.8
u/l
1.50
296
2535
15
79
1.83
1.32
9.5
3.2
24.8
23.0
mmol/l
0.71
15
74
14
72
1.87
1.32
7.4
2.4
—
—
—
0
0
158
1294
1.21
1.32
15.3
12.1
1.4
1.4
mmol/l
0.55
153
1239
141
1144
1.22
1.29
5.0
3.7
6.6
6.4
e6/l
0.07
125
1000
6
23
2.50
1.29
1.7
1.1
—
—
—
0
0
92
713
1.27
1.27
2.1
1.9
—
—
—
0
0
15
81
1.78
1.23
1.1
1.1
—
—
—
0
0
39
268
1.41
1.21
1.9
1.9
—
—
—
0
0
173
1442
1.19
1.20
17.2
9.9
5.1
5.0
kpa
0.89
165
1395
173
1442
1.19
1.20
17.3
9.9
7.4
7.4
ph
—
6
44
644
5995
1.32
1.18
22.6
16.4
273.0
273.2
e9/l
0.02
620
5648
22
135
1.57
1.16
15.7
5.9
—
—
—
0
0
644
5997
1.32
1.16
22.5
16.3
85.8
85.6
fl
0.34
636
5891
152
1257
1.20
1.15
5.7
3.9
—
—
—
0
0
0
35
0.00
1.13
0.0
1.2
—
—
—
0
0
13
69
1.81
1.13
1.7
1.2
—
—
—
0
0
289
2523
1.16
1.13
21.5
14.8
1.2
1.2
mmol/l
0.16
277
2422
644
6000
1.31
1.13
22.5
16.3
28.9
28.8
pg
0.38
636
5897
45
322
1.36
1.12
5.4
3.8
—
—
—
0
0
644
6001
1.31
1.12
22.6
16.3
4.6
4.6
e12/l
0.01
615
5636
18
107
1.62
1.08
8.1
7.4
7.4
7.4
ph
0.01
18
98
48
350
1.33
1.06
1.0
1.0
8.9
8.8
mu/l
0.04
41
304
644
6006
1.30
1.06
23.3
16.7
133.1
132.5
g/l
0.42
638
5905
87
686
1.24
1.06
1.2
1.2
—
56.8
—
0
7
12
64
1.80
1.04
1.0
1.0
—
—
—
0
0
121
992
1.20
1.01
5.2
4.9
1.1
1.1
inr
0.89
36
258
206
1770
1.16
0.98
5.7
4.8
20.1
25.2
e6/l
0.28
154
1341
30
206
1.41
0.97
5.5
4.6
—
—
—
0
0
0
30
0.00
0.96
0.0
1.0
—
—
—
0
0
7
35
1.92
0.95
1.0
1.0
—
—
—
0
0
90
722
1.22
0.95
1.5
1.5
233.2
360.6
u/ml
0.76
80
683
33
232
1.38
0.94
1.5
1.6
—
—
—
0
0
129
1072
1.18
0.93
1.2
1.2
—
—
—
0
0
193
1659
1.15
0.91
6.2
4.4
—
—
—
0
0
6
27
2.13
0.91
1.0
1.1
—
—
—
0
0
18
253
0.67
0.89
1.1
1.0
—
—
—
0
0
12
68
1.70
0.88
2.2
1.8
—
—
—
0
0
12
68
1.70
0.88
1.5
1.4
—
—
—
0
0
12
68
1.70
0.88
1.5
1.4
—
—
—
0
0
20
130
1.48
0.86
7.5
5.7
—
—
—
0
0
12
69
1.67
0.84
1.5
1.4
—
—
—
0
0
6
108
0.53
0.84
1.3
1.8
—
—
—
0
0
21
139
1.46
0.83
4.7
3.9
—
—
—
0
0
71
565
1.22
0.83
1.5
1.4
23.1
18.6
nmol/l
1.55
57
502
232
2034
1.13
0.82
6.6
5.7
77.2
51.4
e6/l
0.34
160
1384
293
2606
1.13
0.81
19.3
13.6
1.2
1.2
mmol/l
0.22
269
2434
181
1564
1.14
0.79
1.6
1.5
—
—
—
0
0
0
25
0.00
0.78
0.0
2.0
—
1.2
—
0
17
14
86
1.56
0.78
1.1
1.1
—
—
—
0
0
10
56
1.71
0.77
1.8
1.5
—
—
—
0
0
8
127
0.60
0.74
1.8
1.7
—
—
—
0
0
16
103
1.49
0.74
5.6
3.3
17.2
17.9
%
0.46
11
69
151
1296
1.14
0.73
14.6
11.9
—
—
—
0
0
5
24
2.00
0.72
13.4
3.4
10.6
11.6
mmol/l
—
5
19
5
24
2.00
0.72
13.4
3.4
108.0
106.1
mmol/l
—
5
19
11
163
0.64
0.72
1.9
1.3
—
—
—
0
0
39
465
0.79
0.72
1.2
1.1
2.3
8.9
u/ml
—
9
119
318
2858
1.11
0.72
4.8
3.9
575.2
207.5
e6/l
0.27
11
25
120
1015
1.15
0.72
8.4
5.4
—
—
—
0
0
113
953
1.16
0.70
4.4
3.0
—
—
—
0
0
192
1680
1.13
0.69
5.4
4.6
0.7
0.2
e6/l
0.68
139
1256
9
56
1.54
0.69
19.1
8.4
1.3
1.2
mmol/l
—
9
51
9
56
1.54
0.69
8.7
2.6
1.1
1.3
mmol/l
—
9
49
18
121
1.43
0.68
3.4
3.7
3.5
3.3
e9/l
0.22
18
121
5
88
0.54
0.67
4.4
2.4
—
—
—
0
0
7
41
1.64
0.67
1.0
1.2
210.0
259.2
iu/ml
—
7
41
589
5492
1.15
0.66
20.7
15.7
39.3
39.1
%
0.63
540
4923
56
447
1.21
0.66
2.5
2.3
5.6
7.8
iu/l
0.76
36
284
7
42
1.60
0.65
1.1
1.0
—
78.5
—
0
8
107
905
1.15
0.65
4.7
3.1
62.0
56.3
u/l
0.18
101
843
192
1687
1.12
0.65
5.4
4.5
—
—
—
0
0
11
67
1.58
0.64
1.0
1.1
—
—
—
0
0
130
1116
1.14
0.64
4.0
4.1
2.9
2.8
e6/l
0.05
77
644
61
495
1.19
0.62
2.6
2.3
4.9
5.6
u/l
0.41
39
297
11
68
1.55
0.61
1.0
1.3
—
—
—
0
0
562
5234
1.13
0.60
16.4
11.2
24.4
23.7
mg/l
0.16
375
3467
18
125
1.38
0.59
4.7
4.0
50.4
50.2
%
0.02
18
125
90
758
1.15
0.59
3.5
2.9
323.0
336.0
nmol/l
0.29
85
732
0
22
0.00
0.58
0.0
2.7
—
—
—
0
0
29
218
1.28
0.58
5.7
4.4
40.0
6.2
e6/l
0.42
22
155
29
219
1.28
0.56
5.7
4.4
347.9
936.1
e6/l
0.49
22
162
153
1339
1.12
0.56
12.0
10.0
23.7
23.6
mmol/l
0.09
147
1307
15
102
1.41
0.55
1.3
1.4
—
—
—
0
0
356
3250
1.09
0.55
5.3
4.6
7.1
7.0
mm/h
0.05
328
3029
11
152
0.69
0.55
1.4
2.1
—
—
—
0
0
9
58
1.49
0.54
1.0
1.3
—
—
—
0
0
47
378
1.20
0.54
2.6
2.2
9.4
9.0
nmol/l
0.10
35
291
6
37
1.55
0.53
1.0
1.1
—
—
—
0
0
9
59
1.46
0.53
2.1
2.5
—
—
—
0
0
326
2970
1.09
0.52
4.9
4.4
—
—
—
0
0
53
588
0.85
0.52
3.9
3.9
552.7
1473.7
ng/l
1.74
29
338
6
38
1.51
0.52
1.5
1.3
—
—
—
0
0
15
104
1.38
0.51
2.5
2.8
—
—
—
0
0
26
197
1.27
0.50
5.0
3.6
68.8
65.2
%
0.43
26
197
44
494
0.84
0.50
1.2
1.2
10.0
14.8
iu/ml
1.22
11
89
7
43
1.56
0.49
1.0
1.1
317.3
276.8
mg/l
—
7
43
266
2409
1.09
0.48
3.5
2.7
1.1
1.1
mmol/l
0.12
252
2282
7
44
1.52
0.48
1.4
1.5
—
—
—
0
0
7
44
1.52
0.48
1.4
1.5
—
—
—
0
0
7
44
1.52
0.48
1.4
1.5
—
—
—
0
0
25
190
1.27
0.48
4.6
9.7
25.0
23.9
mmol/l
0.97
25
179
7
45
1.49
0.47
8.3
7.3
—
—
—
0
0
54
446
1.17
0.47
1.6
1.9
—
—
—
0
0
37
295
1.21
0.47
24.1
16.4
16.1
16.0
kpa
0.02
37
285
16
114
1.35
0.47
1.1
1.1
—
—
—
0
0
24
182
1.27
0.47
5.6
5.0
—
—
—
0
0
130
1140
1.11
0.47
3.0
2.5
—
—
—
0
0
37
296
1.20
0.46
24.1
16.4
5.2
5.4
kpa
0.45
37
286
276
2762
0.92
0.46
2.5
2.2
5.3
5.3
mmol/l
0.22
243
2517
34
270
1.21
0.45
1.0
1.0
3.0
3.2
kpa
0.58
28
224
107
931
1.11
0.45
1.6
1.7
—
—
—
0
0
13
167
0.74
0.45
1.5
1.8
—
—
—
0
0
26
202
1.24
0.43
4.9
3.6
1.8
1.5
e9/l
0.56
21
138
60
505
1.15
0.42
2.5
2.7
—
—
—
0
0
5
31
1.54
0.42
1.0
1.4
—
—
—
0
0
0
16
0.00
0.41
0.0
1.8
—
22.0
—
0
11
34
274
1.19
0.40
1.0
1.0
-1.9
-2.4
mmol/l
—
8
69
34
274
1.19
0.40
1.0
1.0
—
—
—
0
0
34
274
1.19
0.40
1.0
1.0
7.5
7.3
kpa
0.27
28
227
130
1150
1.10
0.40
3.2
3.5
76.0
103.6
ug/g
0.98
108
898
0
17
0.00
0.40
0.0
1.0
—
—
—
0
0
18
135
1.28
0.39
1.1
1.2
—
—
—
0
0
24
187
1.23
0.39
4.5
3.6
29.0
24.9
%
0.48
24
187
0
18
0.00
0.39
0.0
2.0
—
—
—
0
0
0
18
0.00
0.39
0.0
2.0
—
—
—
0
0
115
1016
1.10
0.37
6.8
4.0
7.4
7.4
ph
0.33
28
157
9
66
1.31
0.37
1.3
1.2
—
—
—
0
0
185
1669
1.08
0.37
3.5
3.4
—
—
—
0
0
31
347
0.85
0.36
1.2
1.1
9.4
7.2
u/ml
0.16
18
197
10
69
1.39
0.36
1.1
1.1
156.6
185.1
mg/l
—
10
64
158
1419
1.08
0.35
12.4
10.9
0.9
1.1
mmol/l
0.38
138
1119
32
261
1.18
0.35
1.7
1.5
—
—
—
0
0
279
2560
1.07
0.35
4.3
3.4
53.9
51.1
ug/l
0.17
263
2434
153
1375
1.08
0.34
12.5
10.7
5.1
5.2
kpa
0.21
153
1341
125
1274
0.92
0.33
3.0
3.4
—
—
—
0
0
158
1424
1.08
0.33
12.5
10.9
5.7
5.8
kpa
0.99
158
1386
60
518
1.12
0.31
2.7
2.4
2326.4
7900.5
u/l
—
9
128
7
93
0.72
0.31
1.0
1.3
—
—
—
0
0
25
202
1.19
0.31
4.7
3.6
471.7
373.2
e6/l
0.29
18
133
59
510
1.11
0.30
2.5
1.9
—
—
—
0
0
23
259
0.84
0.30
1.1
1.2
—
—
—
0
0
12
89
1.29
0.29
2.2
2.3
—
—
—
0
0
18
207
0.83
0.29
1.7
4.2
—
—
—
0
0
43
366
1.13
0.28
6.3
4.6
21.6
24.0
nmol/l
0.43
43
360
13
98
1.27
0.28
1.1
1.2
—
—
—
0
0
201
1838
1.06
0.28
2.5
2.0
—
—
—
0
0
9
112
0.76
0.27
1.1
1.3
13.2
15.3
u/ml
—
9
102
9
113
0.76
0.27
1.1
1.6
—
—
—
0
0
492
4614
1.06
0.27
20.6
13.7
4.0
3.9
mmol/l
0.59
475
4453
24
196
1.17
0.27
4.5
3.6
757.4
526.5
e6/l
0.89
18
140
52
546
0.90
0.27
1.2
1.2
6.7
4.2
u/ml
0.23
16
186
26
214
1.17
0.27
31.3
21.7
97.0
95.9
%
1.55
26
214
25
206
1.16
0.26
1.4
1.2
—
—
—
0
0
9
71
1.21
0.25
3.2
4.7
26.9
25.9
ug/l
—
9
71
13
100
1.25
0.25
4.8
8.5
—
—
—
0
0
10
74
1.29
0.25
1.1
1.0
—
—
—
0
0
10
74
1.29
0.25
1.5
1.1
—
—
—
0
0
30
252
1.14
0.25
3.7
7.3
175.7
232.4
ng/l
0.32
25
233
24
198
1.16
0.24
4.5
3.6
0.2
0.2
e9/l
0.32
18
141
26
216
1.15
0.24
31.3
21.4
0.8
0.8
%
0.23
26
216
25
207
1.16
0.24
1.4
1.2
—
—
—
0
0
79
808
0.92
0.24
1.5
1.8
—
—
—
0
0
183
1677
1.06
0.24
2.0
1.8
—
—
—
0
0
19
212
0.85
0.23
1.6
2.1
—
—
—
0
0
93
943
0.93
0.23
1.8
1.6
—
—
—
0
0
109
984
1.07
0.23
4.5
3.6
0.0
0.0
estimate
0.00
44
332
12
140
0.81
0.23
41.4
25.6
10.4
11.5
%
0.61
12
140
5
38
1.26
0.22
3.8
2.5
30.6
18.2
umol/l
—
5
38
5
38
1.26
0.22
4.6
2.9
1043.2
1339.0
u/ml
—
5
38
5
38
1.26
0.22
3.0
6.0
202.6
226.7
ug/l
—
5
38
5
39
1.23
0.22
1.4
1.0
—
—
—
0
0
29
246
1.13
0.21
1.6
1.4
1.6
3.0
u/ml
0.70
18
179
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
32
340
0.89
0.21
1.7
1.4
—
—
—
0
0
34
292
1.12
0.21
1.9
1.8
—
—
—
0
0
0
12
0.00
0.21
0.0
2.6
—
—
—
0
0
0
13
0.00
0.20
0.0
7.8
—
—
—
0
0
66
588
1.08
0.20
20.5
17.1
1.1
1.3
mmol/l
2.10
61
529
6
46
1.25
0.20
1.0
1.2
—
—
—
0
0
137
1363
0.95
0.20
2.0
2.1
—
—
—
0
0
6
49
1.17
0.19
1.7
1.8
—
—
—
0
0
87
787
1.06
0.18
1.8
1.9
1.2
1.2
mmol/l
0.18
81
734
25
214
1.12
0.17
1.2
1.2
—
—
—
0
0
5
66
0.72
0.17
1.4
1.1
—
—
—
0
0
59
599
0.93
0.16
1.3
1.3
3.7
2.9
u/ml
0.18
39
402
28
294
0.91
0.16
1.1
1.1
1.8
0.4
u/ml
0.36
14
137
33
343
0.91
0.16
1.7
2.4
—
—
—
0
0
8
69
1.11
0.16
4.6
3.1
—
—
—
0
0
406
3820
1.03
0.15
4.0
3.2
14.3
14.4
pmol/l
0.58
369
3431
25
216
1.11
0.15
1.2
1.1
8.6
5.9
iu/ml
—
5
31
14
153
0.87
0.14
1.6
1.7
7.4
6.4
u/ml
—
5
37
11
89
1.18
0.14
1.1
1.3
13.4
3.5
u/ml
—
5
53
69
691
0.95
0.13
1.5
1.9
—
—
—
0
0
15
126
1.14
0.13
2.2
1.6
—
—
—
0
0
17
145
1.12
0.12
3.2
3.1
—
650.9
—
0
9
270
2532
1.03
0.12
3.3
2.7
2.5
2.6
mmol/l
0.23
252
2365
70
698
0.95
0.12
1.5
1.9
—
—
—
0
0
251
2439
0.97
0.12
1.9
1.9
2.8
3.7
u/ml
0.43
43
422
31
318
0.93
0.12
1.1
1.1
4.8
10.5
u/ml
0.93
17
198
24
210
1.09
0.12
22.6
14.4
113.8
123.2
g/l
1.25
24
204
27
238
1.09
0.11
1.4
1.6
1418.6
1069.3
nmol/l
0.99
20
178
222
2078
1.03
0.11
4.0
3.5
0.0
0.0
estimate
0.00
41
324
26
229
1.09
0.11
1.6
1.5
16.7
14.1
u/ml
0.06
17
162
22
192
1.10
0.11
28.7
20.3
—
—
—
0
0
43
388
1.06
0.11
1.7
1.4
—
—
—
0
0
70
695
0.96
0.10
1.5
1.9
—
—
—
0
0
99
973
0.97
0.09
1.7
1.5
90.3
97.9
pmol/l
0.76
54
514
30
305
0.94
0.09
1.1
1.4
—
—
—
0
0
20
207
0.92
0.09
1.1
1.3
140.6
219.4
miu/ml
—
10
85
44
400
1.05
0.09
3.5
4.0
1331.9
150.9
mg/l
0.44
39
328
31
314
0.94
0.09
1.4
1.1
—
—
—
0
0
488
4624
1.02
0.09
20.8
13.8
139.5
139.4
mmol/l
0.35
471
4488
239
2315
0.98
0.09
4.1
3.1
35.3
36.1
mmol/mol
0.56
220
2180
450
4261
1.02
0.08
4.1
3.6
2.1
2.0
mu/l
0.70
420
4002
28
251
1.07
0.08
1.3
1.2
—
—
—
0
0
25
223
1.07
0.08
1.1
1.1
—
—
—
0
0
6
56
1.02
0.08
1.3
1.2
—
—
—
0
0
57
565
0.96
0.08
1.2
1.2
5.9
6.4
u/ml
0.11
40
423
10
84
1.14
0.08
1.2
1.1
—
—
—
0
0
220
2069
1.02
0.08
5.8
5.2
0.0
0.0
estimate
0.00
44
353
109
1016
1.03
0.07
2.9
3.0
1.0
1.0
kg/l
0.29
22
194
6
69
0.83
0.07
1.0
1.1
—
—
—
0
0
6
69
0.83
0.07
1.5
2.8
8.8
122.0
u/ml
—
6
57
75
737
0.97
0.07
1.7
1.6
—
—
—
0
0
17
150
1.08
0.07
1.6
1.3
—
—
—
0
0
70
687
0.97
0.06
1.5
1.9
—
—
—
0
0
9
96
0.89
0.06
1.0
1.1
—
—
—
0
0
34
310
1.05
0.06
19.9
16.9
122.8
126.8
g/l
0.50
34
301
11
115
0.91
0.05
1.2
1.2
—
—
—
0
0
18
183
0.94
0.05
1.3
1.2
1.0
1.1
u/ml
—
5
56
266
2516
1.01
0.05
3.3
2.7
1.3
1.4
mmol/l
1.93
248
2365
48
472
0.97
0.05
1.4
1.3
158.3
165.0
iu/ml
0.04
18
131
18
182
0.94
0.04
1.4
1.2
—
—
—
0
0
71
664
1.02
0.04
2.0
1.6
380.0
586.4
titre
—
8
106
18
163
1.06
0.03
1.1
1.1
—
—
—
0
0
67
651
0.98
0.03
1.5
1.9
—
—
—
0
0
51
476
1.02
0.03
1.3
2.5
—
—
—
0
0
242
2323
0.99
0.02
1.8
1.7
1.4
1.5
g/l
0.13
115
1162
273
2593
1.01
0.02
3.5
2.9
4.2
4.2
mmol/l
0.81
254
2459
219
2078
1.01
0.02
4.1
3.6
0.0
0.0
estimate
0.00
45
344
11
98
1.07
0.02
1.1
1.5
—
238.6
—
0
7
11
111
0.94
0.01
4.3
4.8
—
—
—
0
0
11
99
1.06
0.01
1.7
1.6
—
—
—
0
0
22
204
1.03
0.01
3.6
3.9
—
—
—
0
0
36
338
1.02
0.00
1.2
1.1
—
19.4
—
0
5
18
176
0.98
0.00
1.3
1.2
—
—
—
0
0
12
112
1.02
0.00
1.6
1.2
—
0.2
—
0
6
58
554
1.00
0.00
1.2
1.2
1.0
1.1
u/ml
0.10
39
396
19
184
0.99
0.00
27.7
21.2
72.1
71.1
%
0.10
19
184
42
396
1.01
0.00
3.9
4.5
3.8
44.6
mg/mmol
0.63
37
324
15
144
0.99
0.00
6.2
5.8
3.7
2.0
ug/l
1.33
15
144
15
144
0.99
0.00
1.3
1.4
—
—
—
0
0
25
242
0.99
0.00
1.1
1.1
—
—
—
0
0
13
129
0.96
0.00
1.6
1.4
—
—
—
0
0
21
198
1.01
0.00
37.3
19.9
—
—
—
0
0
18
177
0.97
0.00
6.1
5.5
—
—
—
0
0
58
555
1.00
0.00
1.5
2.0
—
—
—
0
0
10
100
0.95
0.00
4.5
4.9
—
—
—
0
0
62
595
0.99
0.00
2.7
2.4
12.4
53.1
ng/l
1.75
30
209
85
810
1.00
0.00
1.5
1.4
113.0
243.3
titre
—
5
32
14
129
1.04
0.00
2.4
1.8
111.0
137.6
ng/l
1.28
14
121
14
132
1.01
0.00
2.4
2.5
1.3
2.1
mmol/l
—
9
105
6
62
0.92
0.00
5.5
2.4
3.0
1.6
ug/l
—
6
56
5
55
0.87
0.00
1.2
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
2.2
—
1492.7
—
0
6
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
2.3
—
—
—
0
0
9
85
1.01
0.00
1.1
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
2.5
—
—
—
0
0
6
64
0.89
0.00
3.2
6.9
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
2.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
7.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
232.5
—
0
6
0
9
0.00
0.00
0.0
15.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
4.2
—
6.9
—
0
5
5
53
0.90
0.00
26.2
3.8
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: P16_HAEMORRHAGIC_HAEMATOL_DISORD_FETUS_NEWBO – Haemorrhagic and haematological disorders of fetus and newborn

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).