No definition available.
Neonatal jaundice from other and unspecified causes
P16_NEONTAL_JAUND_OTH_UNSP_CAUSES
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
536 |
4. Check minimum number of eventsNone |
536 |
5. Include endpointsNone |
536 |
6. Filter based on genotype QC (FinnGen only) |
536 |
Control definitions (FinnGen only)
- Control exclude
- P16_HAEMORRHAGIC_HAEMATOL_DISORD_FETUS_NEWBO
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- P[5-6]
- Name in latin
- Icterus neonatalis ex causis aliis et non specificatis
Similar endpoints
↥List of similar endpoints to
Neonatal jaundice from other and unspecified causes
based on the number of shared cases.
Similar with more cases:
- Haemorrhagic and haematological disorders of fetus and newborn
- Certain conditions originating in the perinatal period
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 54258 | 22632 | 31624 |
| Only index persons | 20837 | 8616 | 12221 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.79 | 0.65 | 0.88 |
| Only index persons | 0.40 | 0.32 | 0.47 |
| Median age at first event (years) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.01 | 0.01 | 0.01 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 536 | 278 | 258 |
| Unadjusted period prevalence (%) | 0.10 | 0.09 | 0.11 |
| Median age at first event (years) | 0.01 | 0.01 | 0.01 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 459
- Matched controls
- 4456
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
P59.9
ICD-10 Finland
Neonatal jaundice, unspecified
3535.7
323.0
283
*
P59.0
ICD-10 Finland
Neonatal jaundice associated with preterm delivery
+∞
191.9
172
*
P07.3
ICD-10 Finland
Other preterm infants
18.8
100.8
165
129
Z87.6
ICD-10 Finland
Personal history of certain conditions arising in the perinatal period
6.8
35.2
96
167
P59.3
ICD-10 Finland
Neonatal jaundice from breast milk inhibitor
+∞
19.7
19
*
P70.4
ICD-10 Finland
Other neonatal hypoglycaemia
6.8
17.9
46
72
P07.11
ICD-10 Finland
Other low birth weight 1500-1999 g
11.9
16.0
29
25
P22.0
ICD-10 Finland
Respiratory distress syndrome of newborn
9.7
11.6
23
24
P59.8
ICD-10 Finland
Neonatal jaundice from other specified causes
+∞
11.4
11
*
AA5HE
NOMESCO Finland
Brain ultrasound examination in a child
2.6
7.2
52
206
P22.8
ICD-10 Finland
Other respiratory distress of newborn
8.3
7.2
15
18
WX722
NOMESCO Finland
PEEP
3.5
7.2
32
93
R17
ICD-10 Finland
Hyperbilirubinaemia, with or without jaundice, not elsewhere classified
11.9
7.0
12
10
602
Kela drug reimbursment
Children's severe malnutrition
2.8
6.8
41
149
P01.5
ICD-10 Finland
Fetus and newborn affected by multiple pregnancy
6.1
6.7
17
28
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
5.9
6.5
17
29
P07.10
ICD-10 Finland
Other low birth weight 1000-1499 g
9.9
6.4
12
12
P00.0
ICD-10 Finland
Fetus and newborn affected by maternal hypertensive disorders
6.8
6.4
15
22
WX882
NOMESCO Finland
High dependency care
2.0
6.3
79
414
Mortality – FinRegistry
↥Association
Association between endpoint P16_NEONTAL_JAUND_OTH_UNSP_CAUSES and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| P16_NEONTAL_JAUND_OTH_UNSP_CAUSES | 0.886 [0.66, 1.18] | 0.414 |
| Birth year | 0.992 [0.98, 1.0] | 0.071 |
During the follow-up period (1.1.1998 — 31.12.2019), 56 out of 21667 females with P16_NEONTAL_JAUND_OTH_UNSP_CAUSES died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| P16_NEONTAL_JAUND_OTH_UNSP_CAUSES | 1.62 [1.3, 2.02] | < 0.001 |
| Birth year | 0.984 [0.97, 0.99] | 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 98 out of 30217 males with P16_NEONTAL_JAUND_OTH_UNSP_CAUSES died.
Mortality risk
Mortality risk for people of age
years, who have P16_NEONTAL_JAUND_OTH_UNSP_CAUSES.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.074% | 0.285% |
| 5 | 0.496% | 1.797% |
| 10 | 1.153% | 4.374% |
| 15 | 2.246% | 8.121% |
| 20 | 4.072% | 13.464% |
Relationships between endpoints
↥Index endpoint: P16_NEONTAL_JAUND_OTH_UNSP_CAUSES – Neonatal jaundice from other and unspecified causes
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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