Neonatal jaundice from other and unspecified causes

P16_NEONTAL_JAUND_OTH_UNSP_CAUSES

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 P59
  • Cause of death: ICD-10 P59

2 out of 7 registries used, show all original rules.

536

4. Check minimum number of events

None

536

5. Include endpoints

None

536

6. Filter based on genotype QC (FinnGen only)

536

Control definitions (FinnGen only)

Control exclude
P16_HAEMORRHAGIC_HAEMATOL_DISORD_FETUS_NEWBO

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
P[5-6]
Name in latin
Icterus neonatalis ex causis aliis et non specificatis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 54258 22632 31624
Only index persons 20837 8616 12221
Unadjusted period prevalence (%)
Whole population 0.79 0.65 0.88
Only index persons 0.40 0.32 0.47
Median age at first event (years)
Whole population 0.01 0.01 0.01
Only index persons 0.01 0.01 0.01

-FinnGen-

Key figures

All Female Male
Number of individuals 536 278 258
Unadjusted period prevalence (%) 0.10 0.09 0.11
Median age at first event (years) 0.01 0.01 0.01

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
459
Matched controls
4456
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
P59.9
ICD-10 Finland
Neonatal jaundice, unspecified
3535.7
323.0
283
*
P59.0
ICD-10 Finland
Neonatal jaundice associated with preterm delivery
+∞
191.9
172
*
P07.3
ICD-10 Finland
Other preterm infants
18.8
100.8
165
129
Z87.6
ICD-10 Finland
Personal history of certain conditions arising in the perinatal period
6.8
35.2
96
167
P59.3
ICD-10 Finland
Neonatal jaundice from breast milk inhibitor
+∞
19.7
19
*
P70.4
ICD-10 Finland
Other neonatal hypoglycaemia
6.8
17.9
46
72
P07.11
ICD-10 Finland
Other low birth weight 1500-1999 g
11.9
16.0
29
25
P22.0
ICD-10 Finland
Respiratory distress syndrome of newborn
9.7
11.6
23
24
P59.8
ICD-10 Finland
Neonatal jaundice from other specified causes
+∞
11.4
11
*
AA5HE
NOMESCO Finland
Brain ultrasound examination in a child
2.6
7.2
52
206
P22.8
ICD-10 Finland
Other respiratory distress of newborn
8.3
7.2
15
18
WX722
NOMESCO Finland
PEEP
3.5
7.2
32
93
R17
ICD-10 Finland
Hyperbilirubinaemia, with or without jaundice, not elsewhere classified
11.9
7.0
12
10
602
Kela drug reimbursment
Children's severe malnutrition
2.8
6.8
41
149
P01.5
ICD-10 Finland
Fetus and newborn affected by multiple pregnancy
6.1
6.7
17
28
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
5.9
6.5
17
29
P07.10
ICD-10 Finland
Other low birth weight 1000-1499 g
9.9
6.4
12
12
P00.0
ICD-10 Finland
Fetus and newborn affected by maternal hypertensive disorders
6.8
6.4
15
22
WX882
NOMESCO Finland
High dependency care
2.0
6.3
79
414

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
35
113
3.14
8.44
6.5
4.6
22.4
24.7
umol/l
0.63
35
113
18
51
3.50
5.35
2.5
2.0
—
—
—
0
0
171
1256
1.47
3.96
20.2
9.5
51.8
27.1
umol/l
3.52
163
1141
36
210
1.71
2.27
5.4
3.3
35.8
35.6
umol/l
0.03
36
190
45
279
1.61
2.26
1.7
1.3
—
—
—
0
0
39
234
1.66
2.23
10.4
5.8
0.0
0.0
%
—
9
69
19
91
2.06
2.17
2.9
2.0
—
—
—
0
0
6
14
4.18
2.09
1.8
1.9
—
—
—
0
0
38
234
1.62
1.99
9.2
4.9
0.1
0.5
%
—
8
58
291
2516
1.26
1.92
13.3
11.9
0.0
0.0
e9/l
0.78
224
1889
8
28
2.79
1.79
5.3
1.9
32.9
31.6
pg
—
8
28
9
34
2.59
1.79
1.9
2.7
—
—
—
0
0
395
3565
1.28
1.72
13.1
9.4
26.9
25.6
u/l
0.51
386
3439
6
18
3.25
1.69
1.7
1.1
—
—
—
0
0
37
239
1.54
1.62
11.0
5.8
0.0
0.1
%
—
9
79
39
255
1.52
1.62
10.8
5.7
0.2
0.6
%
—
10
86
83
625
1.34
1.59
1.9
1.9
—
—
—
0
0
80
601
1.34
1.56
7.5
6.4
1.3
2.1
mg/l
1.29
60
435
20
111
1.77
1.55
2.1
1.3
335.8
386.1
ug/g
0.44
12
60
68
505
1.35
1.44
1.7
1.6
—
—
—
0
0
12
58
2.03
1.38
1.1
1.1
—
—
—
0
0
65
485
1.34
1.34
6.0
5.4
70.1
60.8
e9/l
0.95
45
296
11
53
2.03
1.28
7.4
9.0
—
—
—
0
0
300
2673
1.20
1.26
12.1
9.9
38.6
36.7
%
1.99
289
2573
294
2618
1.19
1.23
12.0
9.8
45.8
47.5
%
1.36
286
2524
12
61
1.92
1.23
1.1
1.1
—
—
—
0
0
434
4014
1.25
1.22
22.4
16.9
13.3
13.2
%
1.47
426
3943
8
37
2.11
1.18
2.1
2.5
—
—
—
0
0
5
19
2.56
1.17
13.4
3.7
108.0
106.4
mmol/l
—
5
14
5
19
2.56
1.17
13.4
3.7
10.6
11.9
mmol/l
—
5
14
0
34
0.00
1.15
0.0
1.1
—
—
—
0
0
47
343
1.36
1.14
2.3
2.2
133.3
172.5
u/ml
0.50
23
149
87
692
1.26
1.14
5.9
4.6
—
—
—
0
0
240
2111
1.18
1.13
12.4
10.6
—
—
—
0
0
289
2583
1.18
1.12
12.5
10.2
8.4
8.4
%
0.01
276
2477
5
20
2.43
1.11
1.0
1.4
—
—
—
0
0
15
87
1.69
1.05
4.5
4.0
1.6
4.6
%
—
7
38
286
2565
1.17
1.03
12.4
10.1
3.3
3.3
%
0.17
278
2459
111
917
1.22
1.03
3.4
3.6
610.6
598.0
mosm/kgh2o
0.19
97
796
298
2687
1.17
0.99
11.7
9.9
2.6
2.4
e9/l
1.08
257
2275
111
921
1.21
0.99
3.6
3.6
6.6
6.4
e6/l
0.05
98
799
10
52
1.88
0.98
2.0
1.9
—
—
—
0
0
87
706
1.23
0.97
2.9
3.0
—
—
—
0
0
53
405
1.30
0.97
1.2
1.4
23.5
18.8
nmol/l
1.33
44
355
280
2517
1.16
0.96
12.5
10.2
0.6
0.6
%
0.24
273
2425
6
27
2.16
0.92
1.0
1.0
—
—
—
0
0
27
357
0.72
0.91
1.3
1.1
2.6
10.4
u/ml
—
7
94
48
366
1.30
0.90
2.7
2.4
2984.4
10237.9
u/l
—
7
95
13
199
0.62
0.90
1.1
1.0
—
—
—
0
0
5
101
0.47
0.90
1.4
10.7
—
1.3
—
0
16
291
2632
1.15
0.89
11.5
10.0
0.6
0.6
e9/l
1.56
244
2155
33
239
1.36
0.87
3.3
3.8
—
—
—
0
0
6
29
2.01
0.87
1.5
1.4
—
—
—
0
0
19
124
1.50
0.86
3.4
2.7
—
—
—
0
0
290
2630
1.15
0.84
11.6
10.0
0.0
0.0
e9/l
1.20
243
2155
297
2699
1.15
0.83
12.4
11.1
0.2
0.2
e9/l
0.28
257
2263
11
63
1.70
0.82
1.0
1.0
—
—
—
0
0
35
260
1.32
0.80
2.9
2.4
—
—
—
0
0
79
649
1.21
0.80
19.5
15.5
0.8
0.8
mmol/l
0.27
79
622
0
25
0.00
0.79
0.0
1.2
—
—
—
0
0
304
2775
1.14
0.78
14.8
11.9
3.3
3.3
e9/l
0.09
252
2278
38
289
1.29
0.75
3.4
9.2
0.3
0.4
g/l
0.24
29
248
423
3956
1.17
0.75
10.8
8.4
—
—
—
0
0
17
113
1.47
0.73
5.4
4.6
—
—
—
0
0
17
113
1.47
0.73
7.9
5.8
—
—
—
0
0
29
213
1.34
0.72
1.9
2.0
—
—
—
0
0
5
25
1.94
0.71
1.4
1.0
—
—
—
0
0
139
1212
1.15
0.70
1.6
1.5
—
—
—
0
0
5
91
0.53
0.67
1.2
1.8
—
—
—
0
0
12
75
1.56
0.67
4.8
7.6
2.5
1.5
mmol/l
—
5
35
12
75
1.56
0.67
4.8
7.6
5.1
4.8
kpa
0.42
12
75
12
75
1.56
0.67
4.8
7.6
9.8
9.0
kpa
0.71
12
75
63
714
0.83
0.66
1.7
1.5
95.3
99.2
pmol/l
0.22
33
366
7
42
1.62
0.66
10.9
2.8
1.0
1.3
mmol/l
—
7
35
24
175
1.34
0.64
3.1
2.2
—
—
—
0
0
24
175
1.34
0.64
3.1
2.2
—
—
—
0
0
24
175
1.34
0.64
3.1
2.2
—
—
—
0
0
24
175
1.34
0.64
3.1
2.2
—
—
—
0
0
36
431
0.79
0.64
2.9
2.3
10.8
61.5
ng/l
1.50
19
149
226
2045
1.12
0.63
9.0
5.5
159.9
141.7
u/l
1.64
218
1917
10
61
1.60
0.61
8.0
2.6
—
—
—
0
0
13
85
1.49
0.61
1.0
1.1
—
—
—
0
0
160
1421
1.13
0.61
4.8
4.8
18.5
23.2
e6/l
0.20
119
1078
126
1103
1.14
0.60
3.7
3.6
2.7
2.7
mg/l
0.03
113
999
19
135
1.38
0.60
2.3
1.9
—
—
—
0
0
0
21
0.00
0.60
0.0
1.0
—
—
—
0
0
28
212
1.29
0.59
2.2
2.9
5.6
5.2
pmol/l
0.49
28
194
43
344
1.23
0.59
1.0
1.0
8.2
8.8
mu/l
0.33
36
298
197
2040
0.90
0.58
2.4
2.1
5.2
5.3
mmol/l
0.69
172
1854
8
52
1.50
0.58
18.5
8.9
1.3
1.2
mmol/l
—
8
47
8
52
1.50
0.58
1.0
1.2
—
—
—
0
0
356
3569
0.89
0.57
21.8
14.8
139.3
139.4
mmol/l
0.03
344
3470
44
355
1.22
0.56
10.7
7.0
264.9
274.2
umol/l
0.28
44
337
40
465
0.82
0.56
4.5
4.3
459.9
1247.0
ng/l
2.41
24
275
80
682
1.16
0.56
1.6
1.7
—
—
—
0
0
6
36
1.62
0.55
1.7
1.4
—
—
—
0
0
11
154
0.68
0.55
1.8
4.3
—
—
—
0
0
32
380
0.80
0.55
1.2
1.2
10.3
15.0
iu/ml
—
9
72
70
592
1.17
0.54
1.4
1.5
279.5
301.3
u/ml
0.08
63
558
37
295
1.23
0.53
2.8
2.2
9.2
8.4
nmol/l
0.17
27
218
22
272
0.77
0.52
1.2
1.1
11.3
7.8
u/ml
0.22
15
157
11
72
1.49
0.52
1.8
1.7
—
—
—
0
0
9
62
1.41
0.51
1.1
1.0
—
—
—
0
0
9
62
1.41
0.51
1.4
1.1
—
—
—
0
0
6
39
1.49
0.51
1.2
1.1
—
87.4
—
0
7
32
253
1.24
0.50
3.0
1.8
2.4
2.4
mmol/l
0.23
27
205
10
65
1.50
0.49
9.4
3.6
25.7
23.3
mmol/l
—
10
60
94
1005
0.88
0.48
3.1
3.4
—
—
—
0
0
150
1346
1.11
0.48
4.8
4.6
0.9
0.2
e6/l
0.74
107
1008
12
82
1.43
0.47
1.3
1.4
—
—
—
0
0
12
82
1.43
0.47
4.8
7.2
7.4
7.4
ph
0.13
12
75
7
46
1.48
0.47
1.9
1.3
—
—
—
0
0
7
46
1.48
0.47
1.9
1.3
—
—
—
0
0
19
235
0.77
0.46
1.2
1.1
2.3
0.4
u/ml
0.38
11
113
7
47
1.45
0.46
1.9
1.4
—
—
—
0
0
181
1862
0.91
0.46
1.8
1.7
1.3
1.4
g/l
0.50
87
919
10
137
0.70
0.46
2.0
1.3
—
—
—
0
0
15
191
0.75
0.45
1.1
1.1
—
—
—
0
0
12
83
1.41
0.45
2.7
2.8
—
—
—
0
0
178
1617
1.10
0.44
9.7
9.6
—
—
—
0
0
33
266
1.21
0.44
1.8
1.5
—
—
—
0
0
5
31
1.57
0.42
1.0
1.2
207.0
235.9
iu/ml
—
5
31
487
4648
1.17
0.41
22.6
17.0
7.0
7.0
e9/l
0.07
465
4363
101
895
1.11
0.41
4.0
4.1
3.1
2.5
e6/l
0.28
58
520
0
15
0.00
0.41
0.0
1.8
—
—
—
0
0
0
15
0.00
0.41
0.0
1.8
—
—
—
0
0
0
16
0.00
0.41
0.0
2.8
—
—
—
0
0
0
16
0.00
0.41
0.0
20.5
—
—
—
0
0
190
1940
0.92
0.40
1.9
1.9
2.3
4.0
u/ml
1.12
35
327
42
351
1.17
0.40
2.8
2.4
4.7
6.3
iu/l
0.79
27
217
21
163
1.26
0.40
1.6
1.6
—
—
—
0
0
149
1350
1.09
0.39
4.8
4.5
—
—
—
0
0
8
59
1.32
0.39
1.6
1.2
—
—
—
0
0
8
59
1.32
0.39
3.5
5.3
28.1
25.6
ug/l
—
8
59
0
18
0.00
0.39
0.0
2.4
—
1.4
—
0
13
5
34
1.43
0.39
1.0
1.1
314.8
284.8
mg/l
—
5
34
96
852
1.11
0.38
1.3
1.2
—
—
—
0
0
233
2156
1.08
0.38
14.4
9.4
5.9
5.9
mmol/l
0.13
221
2045
11
142
0.74
0.37
1.3
1.2
—
—
—
0
0
13
95
1.33
0.37
2.7
3.6
3.5
3.2
e9/l
0.26
13
95
48
525
0.87
0.36
1.6
1.8
—
—
—
0
0
178
1632
1.08
0.36
5.8
5.7
79.3
51.7
e6/l
0.30
124
1111
6
40
1.46
0.36
9.2
7.9
—
—
—
0
0
193
1776
1.08
0.36
3.5
2.8
1.1
1.1
mmol/l
0.50
183
1684
9
121
0.71
0.35
1.3
1.9
—
—
—
0
0
21
166
1.23
0.35
6.2
5.3
—
—
—
0
0
359
3561
0.92
0.35
21.5
14.8
4.0
4.0
mmol/l
0.17
347
3436
11
140
0.76
0.34
1.4
1.8
—
—
—
0
0
65
693
0.89
0.34
1.7
1.6
—
—
—
0
0
6
44
1.32
0.33
1.0
1.1
—
—
—
0
0
238
2213
1.07
0.33
4.0
3.8
788.6
237.8
e6/l
—
8
21
49
531
0.88
0.33
1.6
1.8
—
—
—
0
0
49
529
0.89
0.31
1.6
1.8
—
—
—
0
0
112
1157
0.92
0.31
14.3
11.0
5.1
5.2
kpa
0.53
112
1126
13
98
1.29
0.31
2.8
4.0
49.8
49.9
%
0.01
13
98
7
96
0.70
0.31
5.4
5.1
—
—
—
0
0
7
97
0.69
0.31
2.9
1.7
292.9
296.1
mosm/kgh2o
—
7
70
25
283
0.85
0.30
3.5
4.3
2.1
60.2
mg/mmol
0.66
25
236
19
152
1.22
0.29
5.1
10.3
24.9
23.8
mmol/l
0.72
19
143
7
54
1.26
0.29
1.0
1.1
—
—
—
0
0
140
1283
1.08
0.29
6.2
4.6
—
—
—
0
0
15
117
1.25
0.29
5.0
4.5
—
—
—
0
0
13
100
1.26
0.27
1.2
1.2
—
—
—
0
0
49
523
0.90
0.27
1.6
1.7
—
—
—
0
0
22
249
0.85
0.27
1.2
1.1
5.8
10.5
u/ml
0.51
13
157
10
124
0.78
0.27
9.5
5.3
—
—
—
0
0
19
218
0.84
0.27
1.1
1.4
—
—
—
0
0
484
4636
1.12
0.26
22.7
17.1
276.2
274.8
e9/l
0.15
465
4355
9
70
1.25
0.25
1.0
1.2
—
—
—
0
0
9
72
1.21
0.25
1.0
1.1
—
—
—
0
0
484
4638
1.11
0.25
22.6
17.0
85.3
85.2
fl
0.08
478
4555
109
996
1.07
0.25
5.4
4.2
—
—
—
0
0
24
267
0.86
0.25
1.9
2.1
—
—
—
0
0
14
164
0.82
0.24
4.4
4.1
—
—
—
0
0
22
246
0.86
0.24
1.2
1.2
—
—
—
0
0
85
771
1.08
0.23
8.4
5.5
—
—
—
0
0
484
4640
1.11
0.23
22.6
17.0
28.7
28.7
pg
0.09
478
4560
31
266
1.14
0.23
1.0
1.0
2.9
3.2
kpa
1.08
25
220
117
1191
0.94
0.23
14.2
11.3
5.7
5.8
kpa
0.51
117
1158
10
76
1.28
0.23
2.4
2.2
—
—
—
0
0
22
184
1.16
0.23
33.3
22.0
97.0
95.7
%
1.57
22
184
484
4641
1.10
0.23
22.6
17.0
4.6
4.6
e12/l
0.38
460
4347
7
88
0.77
0.22
5.4
5.2
—
—
—
0
0
14
162
0.83
0.22
1.0
1.1
—
—
—
0
0
44
388
1.11
0.22
2.8
2.4
4.9
5.1
u/l
0.07
27
225
12
141
0.82
0.22
1.7
1.3
—
—
—
0
0
22
185
1.16
0.22
33.3
21.9
0.8
0.8
%
0.02
22
185
0
11
0.00
0.21
0.0
2.7
—
—
—
0
0
0
11
0.00
0.21
0.0
1.6
—
82.3
—
0
11
117
1187
0.94
0.21
14.1
11.3
1.0
1.0
mmol/l
0.12
100
923
484
4644
1.10
0.21
23.5
17.5
132.8
131.7
g/l
0.81
479
4566
6
46
1.26
0.20
6.2
5.9
190.2
134.3
umol/l
—
6
23
47
493
0.91
0.20
1.6
1.8
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
32
279
1.12
0.20
1.6
1.4
—
—
—
0
0
31
270
1.12
0.19
1.0
1.0
—
—
—
0
0
31
270
1.12
0.19
1.0
1.0
-1.9
-2.4
mmol/l
—
8
68
31
270
1.12
0.19
1.0
1.0
7.6
7.3
kpa
0.42
25
223
15
123
1.19
0.19
6.2
6.0
3.7
2.1
ug/l
1.23
15
123
19
210
0.87
0.19
1.1
1.2
—
—
—
0
0
6
51
1.14
0.19
1.5
1.1
—
—
—
0
0
171
1709
0.95
0.18
3.8
3.1
35.1
35.9
mmol/mol
0.46
160
1612
14
158
0.85
0.17
2.7
2.2
1.3
0.4
nmol/l
0.68
14
142
42
438
0.92
0.16
1.2
1.2
8.2
4.5
u/ml
0.29
13
151
139
1390
0.96
0.15
2.6
2.0
—
—
—
0
0
192
1906
0.96
0.15
3.5
2.9
4.2
4.2
mmol/l
0.21
181
1811
35
312
1.09
0.15
6.7
4.4
18.9
23.2
nmol/l
1.35
35
307
264
2505
1.04
0.15
5.5
4.5
7.2
7.1
mm/h
0.05
247
2337
242
2293
1.04
0.15
4.2
4.4
—
—
—
0
0
9
79
1.10
0.15
1.1
1.4
—
290.0
—
0
5
7
84
0.80
0.14
2.1
1.5
—
—
—
0
0
7
85
0.79
0.14
1.1
1.6
—
—
—
0
0
85
789
1.05
0.13
5.7
5.0
1.1
1.1
inr
1.35
25
196
332
3255
0.96
0.13
4.2
3.5
2.1
2.1
mu/l
0.18
313
3059
12
100
1.16
0.13
6.3
5.4
—
—
—
0
0
20
175
1.11
0.12
24.3
14.7
116.5
123.7
g/l
0.80
20
169
24
253
0.91
0.12
1.7
1.4
—
—
—
0
0
21
185
1.10
0.11
1.2
1.2
—
—
—
0
0
104
974
1.04
0.11
2.0
2.0
—
—
—
0
0
64
592
1.05
0.11
1.9
1.9
—
—
—
0
0
437
4259
0.96
0.11
22.1
16.7
39.3
38.8
%
1.69
402
3854
136
1282
1.04
0.11
3.1
3.3
—
—
—
0
0
41
420
0.94
0.11
1.6
1.8
—
—
—
0
0
212
2088
0.97
0.11
21.2
14.5
1.2
1.2
mmol/l
0.50
195
1950
55
508
1.05
0.10
2.1
1.5
251.4
415.8
titre
—
7
76
12
131
0.88
0.10
1.2
1.1
—
—
—
0
0
110
1094
0.97
0.10
16.6
12.1
—
—
—
0
0
5
42
1.15
0.10
1.6
1.9
—
—
—
0
0
24
215
1.08
0.10
1.7
1.4
1.8
2.4
u/ml
0.28
16
157
5
45
1.08
0.09
1.2
1.2
—
—
—
0
0
27
244
1.07
0.09
29.8
17.4
16.3
15.8
kpa
0.14
27
235
27
244
1.07
0.09
2.0
1.9
—
—
—
0
0
80
749
1.04
0.09
3.1
3.6
0.0
0.0
estimate
0.00
34
259
27
245
1.07
0.08
29.8
17.3
5.2
5.4
kpa
0.61
27
236
5
59
0.82
0.08
1.0
2.4
9.4
19.7
u/ml
—
5
48
169
1608
1.02
0.08
3.3
3.5
0.0
0.0
estimate
0.00
32
252
96
906
1.03
0.07
3.0
3.4
67.3
95.7
ug/g
0.95
80
708
8
72
1.08
0.07
1.3
1.1
—
—
—
0
0
114
1080
1.03
0.07
17.7
10.4
—
—
—
0
0
9
85
1.02
0.07
1.2
1.2
—
—
—
0
0
35
354
0.95
0.06
1.7
2.0
—
—
—
0
0
9
99
0.88
0.06
1.1
1.3
13.2
12.5
u/ml
—
9
89
115
1134
0.98
0.06
13.4
10.3
23.7
23.6
mmol/l
0.20
109
1103
299
2917
0.98
0.06
4.0
3.2
14.3
14.4
pmol/l
0.41
273
2626
141
1343
1.02
0.06
2.0
1.8
—
—
—
0
0
48
480
0.96
0.06
1.3
1.3
4.0
2.9
u/ml
0.24
34
326
16
145
1.07
0.04
1.1
1.3
145.4
220.1
miu/ml
—
7
61
57
565
0.97
0.04
1.5
1.8
—
—
—
0
0
22
203
1.05
0.04
1.7
1.5
—
—
—
0
0
22
204
1.05
0.03
1.7
1.5
17.5
6.0
u/ml
0.31
16
147
25
251
0.96
0.03
26.1
18.7
122.1
126.2
g/l
0.45
25
244
46
455
0.98
0.02
1.2
1.2
4.7
6.4
u/ml
0.47
34
349
44
416
1.03
0.02
2.7
1.9
—
—
—
0
0
11
114
0.93
0.02
45.1
28.4
10.9
11.5
%
0.30
11
114
37
367
0.97
0.02
2.2
2.6
—
—
—
0
0
19
176
1.05
0.02
1.5
1.3
—
—
—
0
0
36
357
0.97
0.02
1.4
1.3
187.0
164.3
iu/ml
0.13
15
91
166
1617
0.99
0.02
3.4
3.6
0.0
0.0
estimate
0.00
35
274
167
1606
1.01
0.01
5.2
5.3
0.0
0.0
estimate
0.00
34
278
15
152
0.95
0.01
33.6
22.9
74.4
71.3
%
0.41
15
152
19
177
1.04
0.01
1.4
1.3
—
—
—
0
0
17
158
1.04
0.01
4.9
3.7
32.5
24.8
%
0.75
17
158
16
161
0.96
0.01
1.3
1.2
1.0
1.1
u/ml
—
5
53
417
4042
0.99
0.01
16.7
11.7
23.6
24.0
mg/l
0.08
280
2699
190
1846
0.99
0.01
3.2
2.7
1.3
1.4
mmol/l
0.92
178
1744
19
178
1.03
0.00
6.7
5.0
2.4
7.2
e6/l
0.59
13
126
202
1961
0.99
0.00
4.0
3.5
49.0
49.8
ug/l
0.04
192
1867
211
2035
1.01
0.00
23.4
15.9
1.2
1.2
mmol/l
0.34
203
1949
19
179
1.03
0.00
6.7
5.0
439.3
958.8
e6/l
0.32
13
129
17
164
1.00
0.00
1.6
2.0
—
—
—
0
0
19
188
0.98
0.00
1.3
1.3
—
—
—
0
0
17
166
0.99
0.00
5.5
3.7
68.6
65.0
%
0.29
17
166
17
166
0.99
0.00
5.5
3.7
12.4
8.6
%
0.31
17
159
16
159
0.97
0.00
39.1
21.8
—
—
—
0
0
12
111
1.05
0.00
1.1
1.4
—
—
—
0
0
89
860
1.00
0.00
2.9
2.4
—
—
—
0
0
18
169
1.03
0.00
40.7
20.5
—
—
—
0
0
46
446
1.00
0.00
1.2
1.2
1.1
1.2
u/ml
0.03
32
330
80
770
1.01
0.00
2.3
2.9
1.0
1.0
kg/l
0.07
17
146
13
127
0.99
0.00
1.0
1.2
—
—
—
0
0
12
119
0.98
0.00
3.3
3.1
—
691.3
—
0
6
16
153
1.01
0.00
6.4
5.7
—
—
—
0
0
81
781
1.00
0.00
4.8
4.0
7.4
7.4
ph
0.46
20
129
192
1855
1.00
0.00
3.2
2.8
2.5
2.6
mmol/l
0.13
180
1740
56
542
1.00
0.00
1.7
1.6
—
—
—
0
0
17
169
0.97
0.00
5.4
3.7
645.0
384.7
e6/l
0.64
12
109
11
102
1.04
0.00
1.7
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.8
—
—
—
0
0
0
5
0.00
0.00
0.0
2.6
—
—
—
0
0
6
59
0.98
0.00
2.8
3.1
—
—
—
0
0
0
8
0.00
0.00
0.0
3.4
—
—
—
0
0
8
83
0.93
0.00
1.8
1.2
—
0.2
—
0
6
0
9
0.00
0.00
0.0
15.0
—
13.3
—
0
9
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
7
70
0.97
0.00
1.1
1.1
—
—
—
0
0
5
53
0.91
0.00
1.4
1.2
—
—
—
0
0
5
48
1.01
0.00
26.2
4.0
—
—
—
0
0
36
352
0.99
0.00
1.3
2.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
21.8
—
—
—
0
0
0
8
0.00
0.00
0.0
10.3
—
—
—
0
0
0
7
0.00
0.00
0.0
3.4
—
—
—
0
0
0
6
0.00
0.00
0.0
2.2
—
1492.7
—
0
6
6
64
0.91
0.00
1.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
2.2
—
—
—
0
0
8
84
0.92
0.00
2.3
8.7
—
—
—
0
0
7
70
0.97
0.00
2.1
1.6
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint P16_NEONTAL_JAUND_OTH_UNSP_CAUSES and mortality.

Females

Parameter HR [95% CI] p-value
P16_NEONTAL_JAUND_OTH_UNSP_CAUSES 0.886 [0.66, 1.18] 0.414
Birth year 0.992 [0.98, 1.0] 0.071

During the follow-up period (1.1.1998 — 31.12.2019), 56 out of 21667 females with P16_NEONTAL_JAUND_OTH_UNSP_CAUSES died.

Males

Parameter HR [95% CI] p-value
P16_NEONTAL_JAUND_OTH_UNSP_CAUSES 1.62 [1.3, 2.02] < 0.001
Birth year 0.984 [0.97, 0.99] 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 98 out of 30217 males with P16_NEONTAL_JAUND_OTH_UNSP_CAUSES died.

Mortality risk

Mortality risk for people of age

years, who have P16_NEONTAL_JAUND_OTH_UNSP_CAUSES.

N-year risk Females Males
1 0.074% 0.285%
5 0.496% 1.797%
10 1.153% 4.374%
15 2.246% 8.121%
20 4.072% 13.464%

Relationships between endpoints

Index endpoint: P16_NEONTAL_JAUND_OTH_UNSP_CAUSES – Neonatal jaundice from other and unspecified causes

GWS hits: 2

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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