Neonatal jaundice from other and unspecified causes

P16_NEONTAL_JAUND_OTH_UNSP_CAUSES

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 P59
  • Cause of death: ICD-10 P59

2 out of 7 registries used, show all original rules.

536

4. Check minimum number of events

None

536

5. Include endpoints

None

536

6. Filter based on genotype QC (FinnGen only)

499

Control definitions (FinnGen only)

Control exclude
P16_HAEMORRHAGIC_HAEMATOL_DISORD_FETUS_NEWBO

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
P[5-6]
Name in latin
Icterus neonatalis ex causis aliis et non specificatis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 54258 22632 31624
Only index persons 20837 8616 12221
Unadjusted period prevalence (%)
Whole population 0.79 0.65 0.88
Only index persons 0.40 0.32 0.47
Median age at first event (years)
Whole population 0.01 0.01 0.01
Only index persons 0.01 0.01 0.01

-FinnGen-

Key figures

All Female Male
Number of individuals 499 259 240
Unadjusted period prevalence (%) 0.10 0.09 0.11
Median age at first event (years) 0.01 0.01 0.01

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
530
Matched controls
5128
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
P59.9
ICD-10 Finland
Neonatal jaundice, unspecified
3866.4
307.7
320
*
P59.0
ICD-10 Finland
Neonatal jaundice associated with preterm delivery
+∞
229.1
205
*
P07.3
ICD-10 Finland
Other preterm infants
20.0
216.3
199
150
Z87.6
ICD-10 Finland
Personal history of certain conditions arising in the perinatal period
7.1
65.3
114
191
P07.11
ICD-10 Finland
Other low birth weight 1500-1999 g
10.6
28.1
32
31
P70.4
ICD-10 Finland
Other neonatal hypoglycaemia
5.5
25.6
53
102
P59.3
ICD-10 Finland
Neonatal jaundice from breast milk inhibitor
+∞
22.8
22
*
P07.12
ICD-10 Finland
Other low birth weight 2000-2499 g
5.8
17.0
32
56
P22.0
ICD-10 Finland
Respiratory distress syndrome of newborn
11.9
15.4
28
24
WX722
NOMESCO Finland
PEEP
3.9
13.6
41
107
P59.8
ICD-10 Finland
Neonatal jaundice from other specified causes
+∞
12.4
12
*
AA5HE
NOMESCO Finland
Brain ultrasound examination in a child
2.8
11.5
60
221
P70.0
ICD-10 Finland
Syndrome of infant of mother with gestational diabetes
4.4
9.9
25
57
602
Kela drug reimbursment
Children's severe malnutrition
2.7
8.1
46
177
P01.5
ICD-10 Finland
Fetus and newborn affected by multiple pregnancy
6.2
7.9
20
32
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
4.6
7.6
18
39
A03FA02
ATC
cisapride; oral, rectal
3.6
7.3
24
67
P22.8
ICD-10 Finland
Other respiratory distress of newborn
7.2
7.1
16
22
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.8
7.0
124
746
P07.10
ICD-10 Finland
Other low birth weight 1000-1499 g
8.7
6.9
14
16
WW805
NOMESCO Finland
Transfer from treating institution to lower-Level care, accompanied by paramedic/nurse
10.8
6.7
12
11
P00.0
ICD-10 Finland
Fetus and newborn affected by maternal hypertensive disorders
4.3
6.7
17
39
WX882
NOMESCO Finland
High dependency care
1.9
6.6
83
446
P22.1
ICD-10 Finland
Transient tachypnoea of newborn
2.9
6.6
31
108
P07.2
ICD-10 Finland
Extreme immaturity
8.6
6.4
13
15
A11JC
ATC
Vitamins, other combinations
6.1
6.3
16
26
Q44.29
ICD-10 Finland
Atresia of bile ducts
10.8
6.2
11
10
JKD50
NOMESCO Finland
Hepatoportoenterostomy
10.8
6.2
11
10
P55.1
ICD-10 Finland
ABO isoimmunization of fetus and newborn
+∞
6.2
6
*

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
35
113
3.14
8.44
6.5
4.6
22.40
24.68
umol/l
0.63
35
113
18
51
3.50
5.35
2.5
2.0
—
—
—
0
0
171
1256
1.47
3.96
20.2
9.5
51.86
27.10
umol/l
3.52
163
1142
36
210
1.71
2.27
5.4
3.3
35.81
35.34
umol/l
0.06
36
193
45
279
1.61
2.26
1.7
1.3
—
—
—
0
0
39
235
1.65
2.20
10.4
5.8
0.14
0.02
%
0.61
14
84
19
91
2.06
2.17
2.9
2.0
—
—
—
0
0
38
235
1.61
1.95
9.2
4.9
0.23
0.43
%
0.71
13
100
291
2516
1.26
1.92
13.3
11.9
0.00
0.01
e9/l
0.78
224
1889
8
28
2.79
1.79
5.3
1.9
32.88
31.57
pg
—
8
28
9
34
2.59
1.79
1.9
2.7
—
—
—
0
0
395
3565
1.28
1.72
13.1
9.4
26.91
25.65
u/l
0.51
386
3439
6
18
3.25
1.69
1.7
1.1
—
—
—
0
0
37
239
1.54
1.62
11.0
5.8
0.00
0.05
%
0.64
12
93
39
255
1.52
1.62
10.8
5.7
0.40
0.56
%
0.30
15
108
6
19
3.08
1.60
1.8
1.8
—
—
—
0
0
6
19
3.08
1.60
1.3
2.8
66.67
24.74
u/l
—
6
19
83
626
1.34
1.57
1.9
1.9
—
—
—
0
0
20
111
1.77
1.55
2.1
1.3
335.83
386.12
ug/g
0.44
12
60
80
602
1.34
1.54
7.5
6.4
1.27
2.14
mg/l
1.28
60
436
68
505
1.35
1.44
1.7
1.6
—
—
—
0
0
12
58
2.03
1.38
1.1
1.1
—
—
—
0
0
436
4020
1.28
1.36
22.7
17.0
13.47
13.23
%
1.31
428
3950
65
485
1.34
1.34
5.9
5.4
70.13
60.79
e9/l
0.95
45
296
11
53
2.03
1.28
7.4
9.0
—
—
—
0
0
300
2675
1.20
1.24
12.1
9.9
38.55
36.66
%
1.98
290
2581
12
61
1.92
1.23
1.1
1.1
—
—
—
0
0
294
2619
1.19
1.22
12.1
9.8
45.83
47.51
%
1.38
286
2527
5
19
2.56
1.17
13.4
3.7
108.00
106.36
mmol/l
—
5
14
5
19
2.56
1.17
13.4
3.7
10.60
11.86
mmol/l
—
5
14
0
34
0.00
1.15
0.0
1.1
—
—
—
0
0
87
692
1.26
1.14
5.9
4.6
—
—
—
0
0
289
2584
1.18
1.11
12.6
10.2
8.36
8.36
%
0.00
276
2479
5
20
2.43
1.11
1.0
1.4
—
—
—
0
0
47
347
1.34
1.07
2.3
2.2
133.28
170.21
u/ml
0.46
23
150
15
87
1.69
1.05
4.5
4.0
1.61
4.58
%
—
7
38
286
2567
1.17
1.02
12.4
10.1
3.27
3.34
%
0.16
278
2464
111
920
1.21
1.00
3.4
3.6
613.91
597.62
mosm/kgh2o
0.26
97
799
111
921
1.21
0.99
3.6
3.6
6.60
6.45
e6/l
0.04
99
816
10
52
1.88
0.98
2.0
1.9
—
—
—
0
0
298
2689
1.17
0.98
11.7
9.9
2.59
2.44
e9/l
1.08
257
2280
87
706
1.23
0.97
2.9
3.0
—
—
—
0
0
53
405
1.30
0.97
1.2
1.4
23.45
18.76
nmol/l
1.33
44
355
280
2518
1.16
0.95
12.5
10.2
0.63
0.61
%
0.24
273
2426
6
27
2.16
0.92
1.0
1.0
—
—
—
0
0
27
357
0.72
0.91
1.3
1.1
2.61
10.44
u/ml
—
7
94
48
366
1.30
0.90
2.7
2.4
2984.37
10131.30
u/l
—
7
96
13
199
0.62
0.90
1.1
1.0
—
—
—
0
0
291
2634
1.15
0.88
11.5
10.0
0.62
0.57
e9/l
1.55
244
2158
33
239
1.36
0.87
3.3
3.8
—
—
—
0
0
6
29
2.01
0.87
1.5
1.4
—
—
—
0
0
19
124
1.50
0.86
3.4
2.7
—
—
—
0
0
290
2631
1.15
0.83
11.6
10.0
0.04
0.04
e9/l
1.19
243
2156
11
63
1.70
0.82
1.0
1.0
—
—
—
0
0
297
2701
1.15
0.82
12.4
11.1
0.23
0.22
e9/l
0.28
257
2265
35
260
1.32
0.80
2.9
2.4
—
—
—
0
0
79
649
1.21
0.80
19.5
15.5
0.81
0.81
mmol/l
0.19
79
624
0
25
0.00
0.79
0.0
1.2
—
—
—
0
0
5
97
0.49
0.78
1.2
1.9
—
—
—
0
0
423
3952
1.18
0.78
10.8
8.4
—
—
—
0
0
304
2776
1.14
0.77
14.8
11.9
3.28
3.32
e9/l
0.09
252
2279
38
289
1.29
0.75
3.4
9.2
0.27
0.36
g/l
0.24
29
248
17
113
1.47
0.73
5.4
4.6
—
—
—
0
0
17
113
1.47
0.73
7.8
5.8
—
—
—
0
0
29
213
1.34
0.72
1.9
2.0
—
—
—
0
0
139
1212
1.15
0.70
1.6
1.5
—
—
—
0
0
5
26
1.87
0.69
1.4
1.0
—
—
—
0
0
12
75
1.56
0.67
4.8
7.6
2.48
1.53
mmol/l
—
5
35
12
75
1.56
0.67
4.8
7.6
9.85
9.03
kpa
0.71
12
75
12
75
1.56
0.67
4.8
7.6
5.11
4.84
kpa
0.42
12
75
63
714
0.83
0.66
1.7
1.5
95.30
99.21
pmol/l
0.22
33
366
7
42
1.62
0.66
10.9
3.1
1.00
1.26
mmol/l
—
7
35
36
432
0.79
0.65
2.9
2.3
10.78
61.49
ng/l
1.50
19
149
226
2045
1.12
0.63
9.0
5.5
159.86
141.60
u/l
1.65
218
1919
10
61
1.60
0.61
8.0
2.6
—
—
—
0
0
13
85
1.49
0.61
1.0
1.1
—
—
—
0
0
160
1421
1.13
0.61
4.8
4.8
18.49
23.19
e6/l
0.20
119
1078
126
1103
1.14
0.60
3.7
3.6
2.70
2.68
mg/l
0.03
113
999
19
135
1.38
0.60
2.3
1.9
—
—
—
0
0
0
21
0.00
0.60
0.0
1.0
—
—
—
0
0
28
212
1.29
0.59
2.2
2.9
5.63
5.21
pmol/l
0.49
28
194
43
344
1.23
0.59
1.0
1.0
8.16
8.77
mu/l
0.33
36
298
197
2040
0.90
0.58
2.4
2.1
5.19
5.28
mmol/l
0.69
172
1854
8
52
1.50
0.58
18.5
8.9
1.26
1.22
mmol/l
—
8
47
356
3569
0.89
0.57
21.8
14.8
139.34
139.35
mmol/l
0.03
344
3470
80
681
1.16
0.57
1.6
1.7
—
—
—
0
0
44
355
1.22
0.56
10.7
7.0
264.86
273.62
umol/l
0.26
44
337
40
465
0.82
0.56
4.5
4.3
459.88
1247.00
ng/l
2.41
24
275
6
36
1.62
0.55
1.7
1.4
—
—
—
0
0
11
154
0.68
0.55
1.8
4.2
—
—
—
0
0
32
380
0.80
0.55
1.2
1.2
10.26
14.94
iu/ml
—
9
73
70
592
1.17
0.54
1.4
1.5
279.50
301.28
u/ml
0.08
63
558
270
2483
1.11
0.54
13.7
10.7
—
—
—
0
0
66
557
1.17
0.53
1.2
1.2
—
7.92
—
0
6
22
272
0.77
0.52
1.2
1.1
11.26
7.74
u/ml
0.22
15
179
11
72
1.49
0.52
1.8
1.7
—
—
—
0
0
9
62
1.41
0.51
1.1
1.0
—
—
—
0
0
9
62
1.41
0.51
1.4
1.1
—
—
—
0
0
6
39
1.49
0.51
1.2
1.1
—
87.43
—
0
7
10
65
1.50
0.49
9.4
3.6
25.71
23.31
mmol/l
—
10
60
32
254
1.23
0.49
3.0
1.8
2.43
2.42
mmol/l
0.24
27
206
94
1005
0.88
0.48
3.1
3.4
—
—
—
0
0
150
1346
1.11
0.48
4.8
4.6
0.88
0.18
e6/l
0.74
107
1011
12
82
1.43
0.47
1.3
1.4
—
—
—
0
0
12
82
1.43
0.47
4.8
7.2
7.40
7.40
ph
0.14
12
76
7
46
1.48
0.47
1.9
1.3
—
—
—
0
0
7
46
1.48
0.47
1.9
1.3
—
—
—
0
0
181
1864
0.91
0.47
1.8
1.7
1.33
1.42
g/l
0.52
87
921
19
235
0.77
0.46
1.2
1.1
2.31
0.37
u/ml
0.38
11
116
7
47
1.45
0.46
1.9
1.4
—
—
—
0
0
10
137
0.70
0.46
2.0
1.3
—
—
—
0
0
15
191
0.75
0.45
1.1
1.1
—
—
—
0
0
12
83
1.41
0.45
2.7
2.8
—
—
—
0
0
178
1617
1.10
0.44
9.7
9.6
—
—
—
0
0
33
266
1.21
0.44
1.8
1.5
—
—
—
0
0
487
4646
1.17
0.43
22.6
17.0
6.99
7.02
e9/l
0.07
465
4361
5
31
1.57
0.42
1.0
1.2
207.00
235.95
iu/ml
—
5
31
190
1943
0.92
0.42
1.9
1.9
2.28
3.97
u/ml
1.11
35
328
101
895
1.11
0.41
4.0
4.1
3.12
2.49
e6/l
0.28
58
520
0
15
0.00
0.41
0.0
1.8
—
—
—
0
0
0
16
0.00
0.41
0.0
20.5
—
—
—
0
0
0
16
0.00
0.41
0.0
2.8
—
—
—
0
0
42
351
1.17
0.40
2.8
2.4
4.69
6.26
iu/l
0.79
27
217
21
163
1.26
0.40
1.6
1.6
—
—
—
0
0
149
1350
1.09
0.39
4.8
4.5
—
—
—
0
0
8
59
1.32
0.39
1.6
1.2
—
—
—
0
0
8
59
1.32
0.39
3.5
5.3
28.15
25.58
ug/l
—
8
59
0
18
0.00
0.39
0.0
2.4
—
1.38
—
0
13
5
34
1.43
0.39
1.0
1.1
314.80
284.76
mg/l
—
5
34
34
384
0.85
0.38
10.5
9.2
1499.59
1394.26
ng/l
0.06
29
333
96
853
1.11
0.38
1.3
1.2
—
—
—
0
0
233
2156
1.08
0.38
14.4
9.4
5.86
5.94
mmol/l
0.13
221
2046
11
142
0.74
0.37
1.3
1.2
—
—
—
0
0
13
95
1.33
0.37
2.7
3.6
3.52
3.19
e9/l
0.26
13
95
178
1631
1.08
0.37
5.8
5.7
79.26
51.73
e6/l
0.30
124
1110
48
525
0.87
0.36
1.6
1.8
—
—
—
0
0
6
40
1.46
0.36
9.2
7.9
—
—
—
0
0
193
1776
1.08
0.36
3.5
2.8
1.14
1.08
mmol/l
0.51
183
1684
9
121
0.71
0.35
1.3
1.9
—
—
—
0
0
21
166
1.23
0.35
6.2
5.3
—
—
—
0
0
359
3561
0.92
0.35
21.5
14.8
3.96
3.95
mmol/l
0.16
347
3436
65
693
0.89
0.34
1.7
1.6
—
—
—
0
0
238
2212
1.07
0.34
4.0
3.8
788.62
237.76
e6/l
—
8
21
6
44
1.32
0.33
1.0
1.1
—
—
—
0
0
49
531
0.88
0.33
1.6
1.8
—
—
—
0
0
11
139
0.76
0.33
1.4
1.8
—
—
—
0
0
49
529
0.89
0.31
1.6
1.8
—
—
—
0
0
112
1157
0.92
0.31
14.3
11.0
5.07
5.24
kpa
0.53
112
1126
13
98
1.29
0.31
2.8
4.0
49.77
49.87
%
0.01
13
98
7
96
0.70
0.31
5.4
4.9
—
—
—
0
0
7
97
0.69
0.31
2.9
1.7
292.86
296.06
mosm/kgh2o
—
7
70
25
283
0.85
0.30
3.4
4.2
2.13
60.17
mg/mmol
0.66
25
236
47
407
1.13
0.30
15.4
14.6
106.66
105.78
mmol/l
0.78
47
407
19
152
1.22
0.29
5.1
10.3
24.86
23.80
mmol/l
0.72
19
143
7
54
1.26
0.29
1.0
1.1
—
—
—
0
0
140
1283
1.08
0.29
4.9
3.9
—
—
—
0
0
26
292
0.85
0.29
3.2
3.8
1965.67
180.20
mg/l
0.44
26
245
174
1608
1.07
0.29
12.1
5.1
33.75
26.28
u/l
1.11
163
1548
15
117
1.25
0.29
5.0
4.5
—
—
—
0
0
13
100
1.26
0.27
1.2
1.2
—
—
—
0
0
49
523
0.90
0.27
1.6
1.7
—
—
—
0
0
22
249
0.85
0.27
1.2
1.1
5.84
10.45
u/ml
0.51
13
157
10
124
0.78
0.27
9.5
5.3
—
—
—
0
0
19
218
0.84
0.27
1.1
1.4
—
—
—
0
0
484
4636
1.12
0.26
22.7
17.1
276.21
274.86
e9/l
0.15
465
4355
9
70
1.25
0.25
1.0
1.2
—
—
—
0
0
109
995
1.08
0.25
5.4
4.2
—
—
—
0
0
9
72
1.21
0.25
1.0
1.1
—
—
—
0
0
484
4638
1.11
0.25
22.6
17.0
85.29
85.24
fl
0.07
478
4555
24
267
0.86
0.25
1.9
2.1
—
—
—
0
0
14
164
0.82
0.24
4.1
3.9
—
—
—
0
0
22
246
0.86
0.24
1.2
1.2
—
—
—
0
0
484
4640
1.11
0.23
22.6
17.0
28.70
28.67
pg
0.09
478
4560
31
266
1.14
0.23
1.0
1.0
2.86
3.24
kpa
1.08
25
220
117
1191
0.94
0.23
14.2
11.3
5.70
5.78
kpa
0.51
117
1158
10
76
1.28
0.23
2.4
2.2
—
—
—
0
0
22
184
1.16
0.23
33.3
22.0
97.01
95.73
%
1.57
22
184
484
4641
1.10
0.23
22.6
17.0
4.63
4.61
e12/l
0.39
460
4347
7
88
0.77
0.22
5.4
5.2
—
—
—
0
0
14
162
0.83
0.22
1.0
1.1
—
—
—
0
0
44
388
1.11
0.22
2.8
2.4
4.92
5.12
u/l
0.07
27
225
12
141
0.82
0.22
1.6
1.3
—
—
—
0
0
22
185
1.16
0.22
33.3
21.9
0.76
0.76
%
0.02
22
185
0
11
0.00
0.21
0.0
1.4
—
98.64
—
0
11
0
11
0.00
0.21
0.0
1.6
—
82.25
—
0
11
0
11
0.00
0.21
0.0
1.9
—
106.98
—
0
11
0
11
0.00
0.21
0.0
2.7
—
—
—
0
0
117
1187
0.94
0.21
14.1
11.3
0.96
1.02
mmol/l
0.08
100
926
5
41
1.18
0.21
1.6
1.9
—
—
—
0
0
484
4644
1.10
0.21
23.5
17.5
132.79
131.73
g/l
0.81
479
4566
6
46
1.26
0.20
6.2
5.9
190.17
134.26
umol/l
—
6
23
47
493
0.91
0.20
1.6
1.8
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
32
279
1.12
0.20
1.6
1.4
—
—
—
0
0
31
270
1.12
0.19
1.0
1.0
7.59
7.31
kpa
0.42
25
223
31
270
1.12
0.19
1.0
1.0
-1.87
-2.43
mmol/l
—
8
68
31
270
1.12
0.19
1.0
1.0
—
—
—
0
0
15
123
1.19
0.19
6.2
6.0
3.71
2.13
ug/l
1.23
15
123
483
4636
1.09
0.19
24.8
18.4
39.55
39.14
%
1.27
468
4453
19
210
0.87
0.19
1.1
1.2
—
—
—
0
0
6
51
1.14
0.19
2.0
1.9
—
—
—
0
0
171
1709
0.95
0.18
3.8
3.1
35.11
35.95
mmol/mol
0.46
160
1612
14
158
0.85
0.17
2.7
2.2
1.29
0.42
nmol/l
0.68
14
142
42
438
0.92
0.16
1.2
1.2
10.65
3.48
u/ml
1.32
34
333
167
1567
1.05
0.16
4.6
3.9
69.54
68.44
nmol/l
0.23
158
1488
139
1391
0.96
0.16
2.6
2.0
—
—
—
0
0
192
1906
0.96
0.15
3.5
2.9
4.19
4.22
mmol/l
0.21
181
1814
35
312
1.09
0.15
6.7
4.4
18.91
23.18
nmol/l
1.35
35
307
242
2292
1.04
0.15
4.2
4.4
—
—
—
0
0
9
79
1.10
0.15
1.1
1.4
—
290.00
—
0
5
7
84
0.80
0.14
2.1
1.5
—
—
—
0
0
7
86
0.78
0.14
1.1
1.6
—
—
—
0
0
264
2507
1.04
0.14
5.5
4.5
7.15
7.07
mm/h
0.04
247
2339
24
255
0.91
0.14
1.7
1.4
—
—
—
0
0
332
3256
0.96
0.13
4.2
3.5
2.10
2.07
mu/l
0.17
313
3060
12
100
1.16
0.13
6.3
5.4
—
—
—
0
0
20
175
1.11
0.12
24.3
14.7
116.45
123.61
g/l
0.78
20
170
21
185
1.10
0.11
1.2
1.2
—
—
—
0
0
104
974
1.04
0.11
2.0
2.0
—
—
—
0
0
64
592
1.05
0.11
1.9
1.9
—
—
—
0
0
41
420
0.94
0.11
1.6
1.8
—
—
—
0
0
24
214
1.09
0.11
1.7
1.4
1.79
2.38
u/ml
0.25
16
157
212
2088
0.97
0.11
21.2
14.5
1.23
1.23
mmol/l
0.48
195
1952
12
131
0.88
0.10
1.2
1.1
—
—
—
0
0
110
1094
0.97
0.10
16.6
12.1
—
—
—
0
0
55
509
1.05
0.10
2.1
1.5
251.43
415.79
titre
—
7
76
80
748
1.04
0.10
3.1
3.6
0.00
0.00
estimate
-0.00
34
259
5
45
1.08
0.09
1.2
1.2
—
—
—
0
0
27
244
1.07
0.09
29.8
17.4
16.28
15.83
kpa
0.14
27
235
27
244
1.07
0.09
1.9
1.9
—
—
—
0
0
27
245
1.07
0.08
29.8
17.3
5.23
5.44
kpa
0.60
27
236
5
59
0.82
0.08
1.0
2.4
9.40
19.71
u/ml
—
5
48
169
1608
1.02
0.08
3.3
3.5
0.00
0.00
estimate
-0.00
35
270
96
906
1.03
0.07
3.0
3.4
67.25
95.93
ug/g
0.97
80
709
8
72
1.08
0.07
1.3
1.1
—
—
—
0
0
114
1080
1.03
0.07
17.7
10.4
—
—
—
0
0
299
2919
0.98
0.07
4.0
3.2
14.30
14.42
pmol/l
0.41
273
2628
9
85
1.02
0.07
1.2
1.2
—
—
—
0
0
35
354
0.95
0.06
1.7
2.0
—
—
—
0
0
9
99
0.88
0.06
1.1
1.3
13.19
12.51
u/ml
—
9
89
115
1134
0.98
0.06
13.4
10.3
23.59
23.42
mmol/l
0.39
115
1134
48
479
0.97
0.05
1.3
1.3
3.90
3.29
u/ml
0.13
37
349
21
192
1.06
0.05
15.6
8.2
22.72
23.01
mmol/l
0.24
21
184
21
214
0.95
0.04
24.4
18.5
0.58
0.63
%
0.35
21
214
141
1347
1.02
0.04
2.0
1.8
—
—
—
0
0
16
145
1.07
0.04
1.1
1.3
145.37
220.14
miu/ml
—
7
61
89
846
1.02
0.04
5.5
6.0
1.05
1.13
inr
1.60
25
208
57
565
0.97
0.04
1.5
1.8
—
—
—
0
0
22
203
1.05
0.04
1.7
1.5
—
—
—
0
0
22
204
1.05
0.03
1.7
1.5
17.47
5.96
u/ml
0.31
16
147
25
251
0.96
0.03
26.1
18.7
122.12
126.24
g/l
0.45
25
244
36
358
0.97
0.03
1.4
1.3
187.02
162.56
iu/ml
0.14
15
92
44
416
1.03
0.02
2.7
1.9
—
—
—
0
0
11
114
0.93
0.02
45.1
28.4
10.90
11.47
%
0.30
11
114
37
367
0.97
0.02
2.2
2.6
—
—
—
0
0
19
176
1.05
0.02
1.5
1.3
—
—
—
0
0
46
454
0.98
0.02
1.2
1.2
4.73
6.40
u/ml
0.47
34
349
167
1605
1.01
0.02
5.2
5.3
0.00
0.00
estimate
-0.00
34
278
166
1616
0.99
0.01
3.4
3.6
0.00
0.00
estimate
-0.00
35
274
15
152
0.95
0.01
33.6
22.9
74.40
71.28
%
0.41
15
152
19
177
1.04
0.01
1.4
1.3
—
—
—
0
0
17
158
1.04
0.01
4.9
3.7
32.47
24.77
%
0.75
17
158
417
4042
0.99
0.01
16.7
11.7
23.56
23.96
mg/l
0.08
280
2699
190
1845
0.99
0.00
3.2
2.7
1.33
1.38
mmol/l
1.16
178
1745
19
178
1.03
0.00
6.7
5.0
2.38
7.24
e6/l
0.59
13
126
202
1961
0.99
0.00
4.0
3.5
49.02
49.79
ug/l
0.04
192
1867
211
2035
1.01
0.00
23.4
15.9
1.24
1.23
mmol/l
0.33
203
1950
19
179
1.03
0.00
6.7
5.0
439.31
958.81
e6/l
0.32
13
129
17
164
1.00
0.00
1.6
2.0
—
—
—
0
0
19
188
0.98
0.00
1.3
1.3
—
—
—
0
0
17
166
0.99
0.00
5.5
3.7
68.65
65.04
%
0.29
17
166
17
166
0.99
0.00
5.5
3.7
13.18
8.60
%
0.39
17
166
16
159
0.97
0.00
39.0
21.8
—
—
—
0
0
32
312
0.99
0.00
2.2
2.6
20.77
26.95
u/l
1.63
26
251
12
111
1.05
0.00
1.1
1.4
—
—
—
0
0
18
169
1.03
0.00
40.7
20.5
—
—
—
0
0
80
770
1.01
0.00
2.3
2.9
1.02
1.02
kg/l
0.07
17
146
13
127
0.99
0.00
1.0
1.2
—
—
—
0
0
192
1854
1.00
0.00
3.2
2.8
2.55
2.57
mmol/l
0.13
180
1742
89
864
1.00
0.00
2.9
2.4
—
—
—
0
0
143
1386
1.00
0.00
3.0
3.2
6.25
6.34
ph
0.16
14
161
16
153
1.01
0.00
6.4
5.7
—
—
—
0
0
81
781
1.00
0.00
4.8
4.0
7.38
7.39
ph
0.46
20
129
46
445
1.00
0.00
1.2
1.2
1.13
1.18
u/ml
0.03
32
330
56
542
1.00
0.00
1.7
1.6
—
—
—
0
0
17
169
0.97
0.00
5.4
3.7
645.00
384.68
e6/l
0.64
12
109
11
102
1.04
0.00
1.7
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
2.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
2.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.2
—
—
—
0
0
36
352
0.99
-0.00
1.3
2.1
—
—
—
0
0
8
83
0.93
-0.00
1.8
1.2
—
0.20
—
0
6
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
7
70
0.97
-0.00
2.1
1.6
—
—
—
0
0
5
53
0.91
-0.00
1.4
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
3.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
21.8
—
—
—
0
0
6
59
0.98
-0.00
2.8
3.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
15.0
—
13.29
—
0
9
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
6
64
0.91
-0.00
1.0
1.2
—
—
—
0
0
5
48
1.01
-0.00
26.0
4.0
—
—
—
0
0
7
70
0.97
-0.00
1.1
1.1
—
—
—
0
0
8
84
0.92
-0.00
2.3
8.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.2
—
1492.67
—
0
6
0
8
0.00
-0.00
0.0
2.9
—
—
—
0
0
0
8
0.00
-0.00
0.0
10.3
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint P16_NEONTAL_JAUND_OTH_UNSP_CAUSES and mortality.

Females

Parameter HR [95% CI] p-value
P16_NEONTAL_JAUND_OTH_UNSP_CAUSES 0.886 [0.66, 1.18] 0.414
Birth year 0.992 [0.98, 1.0] 0.071

During the follow-up period (1.1.1998 — 31.12.2019), 56 out of 21667 females with P16_NEONTAL_JAUND_OTH_UNSP_CAUSES died.

Males

Parameter HR [95% CI] p-value
P16_NEONTAL_JAUND_OTH_UNSP_CAUSES 1.62 [1.3, 2.02] < 0.001
Birth year 0.984 [0.97, 0.99] 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 98 out of 30217 males with P16_NEONTAL_JAUND_OTH_UNSP_CAUSES died.

Mortality risk

Mortality risk for people of age

years, who have P16_NEONTAL_JAUND_OTH_UNSP_CAUSES.

N-year risk Females Males
1 0.074% 0.285%
5 0.496% 1.797%
10 1.153% 4.374%
15 2.246% 8.121%
20 4.072% 13.464%

Relationships between endpoints

Index endpoint: P16_NEONTAL_JAUND_OTH_UNSP_CAUSES – Neonatal jaundice from other and unspecified causes

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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