Disorders related to short gestation and low birth weight, not elsewhere classified

P16_DISORD_RELATED_GESTATION_LOW_BIRTHWGHTT_NECIFIED

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 P07
  • Cause of death: ICD-10 P07

2 out of 7 registries used, show all original rules.

842

4. Check minimum number of events

None

842

5. Include endpoints

None

842

6. Filter based on genotype QC (FinnGen only)

779

Control definitions (FinnGen only)

Control exclude
P16_DISORD_RELATED_LENGTH_GESTATION_FETAL_GROWTH

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
P0[5-8]
Name in latin
Perturbationes ad gestationem brevem et pondus partuale leve pertinentes non alibi classificatae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 51969 23864 28104
Only index persons 27383 12581 14802
Unadjusted period prevalence (%)
Whole population 0.74 0.68 0.79
Only index persons 0.52 0.46 0.57
Median age at first event (years)
Whole population 0.00 0.00 0.00
Only index persons 0.00 0.00 0.00

-FinnGen-

Key figures

All Female Male
Number of individuals 779 450 329
Unadjusted period prevalence (%) 0.16 0.16 0.15
Median age at first event (years) 0.00 0.00 0.00

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
833
Matched controls
8071
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
P07.3
ICD-10 Finland
Other preterm infants
+∞
307.7
674
*
Z87.6
ICD-10 Finland
Personal history of certain conditions arising in the perinatal period
39.3
307.7
351
147
P59.0
ICD-10 Finland
Neonatal jaundice associated with preterm delivery
156.4
307.7
178
14
P07.12
ICD-10 Finland
Other low birth weight 2000-2499 g
+∞
166.7
156
*
P22.0
ICD-10 Finland
Respiratory distress syndrome of newborn
443.6
120.6
119
*
602
Kela drug reimbursment
Children's severe malnutrition
9.6
107.5
140
167
P05.1
ICD-10 Finland
Small for gestational age
+∞
97.8
93
*
P07.11
ICD-10 Finland
Other low birth weight 1500-1999 g
+∞
97.8
93
*
P01.5
ICD-10 Finland
Fetus and newborn affected by multiple pregnancy
197.6
88.1
91
5
P70.4
ICD-10 Finland
Other neonatal hypoglycaemia
10.4
81.8
97
101
P00.0
ICD-10 Finland
Fetus and newborn affected by maternal hypertensive disorders
25.1
79.6
58
24
WX722
NOMESCO Finland
PEEP
10.9
77.8
89
88
P07.2
ICD-10 Finland
Extreme immaturity
+∞
74.3
71
*
P07.1
ICD-10 Finland
Other low birth weight
+∞
74.3
71
*
AA5HE
NOMESCO Finland
Brain ultrasound examination in a child
6.3
64.6
120
210
P27.1
ICD-10 Finland
Bronchopulmonary dysplasia originating in the perinatal period
634.9
61.9
61
*
P05.0
ICD-10 Finland
Light for gestational age
+∞
56.3
54
*
P07.10
ICD-10 Finland
Other low birth weight 1000-1499 g
+∞
49.9
48
*
P70.1
ICD-10 Finland
Syndrome of infant of a diabetic mother
18.3
45.9
38
21
P01.10
ICD-10 Finland
Fetus and newborn affected by premature rupture of membranes 1-7 days before delivery
13.8
43.8
42
31
P22.1
ICD-10 Finland
Transient tachypnoea of newborn
6.6
43.2
73
115
Z38.3
ICD-10 Finland
Twin, born in hospital
93.7
33.5
37
*
JAB00
NOMESCO Finland
Division and ligature of inguinal hernia sac
5.9
32.7
61
106
H35.1
ICD-10 Finland
Retinopathy of prematurity
171.5
32.5
34
*
P29.30
ICD-10 Finland
Delayed closure of the ductus arteriosus
48.1
31.3
38
8
R4110
NOMESCO Finland
Physiotherapy
2.5
30.3
261
1247
E34.31
ICD-10 Finland
Short stature, prenatal disorder
10.1
30.0
35
35
WX730
NOMESCO Finland
Conventional respirator
8.6
26.6
35
41
P07.02
ICD-10 Finland
Extremely low birth weight 750-999 g
+∞
25.9
25
*
WW804
NOMESCO Finland
Transfer from treating institution to higher-Level care, accompanied by doctor
8.7
25.4
33
38
P22.9
ICD-10 Finland
Respiratory distress of newborn, unspecified
7.4
25.4
38
52
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.4
25.2
217
1025
Z3229
NOMESCO Finland
Other healthcare associate professional
2.9
24.8
133
497
A11JC
ATC
Vitamins, other combinations
30.2
24.8
33
11
WX882
NOMESCO Finland
High dependency care
2.8
24.4
136
519
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
2.4
23.7
192
880
J45.1
ICD-10 Finland
Nonallergic asthma
2.7
23.6
144
575
K40.9
ICD-10 Finland
Unilateral or unspecified inguinal hernia, without obstruction or gangrene
4.3
23.2
62
147
F82
ICD-10 Finland
Specific developmental disorder of motor function
3.9
22.2
69
183
XG413
NOMESCO Finland
Spirometry with oscillometry
4.7
20.7
50
109
P07.01
ICD-10 Finland
Extremely low birth weight 500-749 g
+∞
20.7
20
*
WW805
NOMESCO Finland
Transfer from treating institution to lower-Level care, accompanied by paramedic/nurse
57.2
19.7
23
*
Z3226
NOMESCO Finland
Physiotherapist
2.2
19.6
224
1178
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.9
19.2
101
372
Z2446
NOMESCO Finland
Social worker
2.2
18.5
183
906
Z01.1
ICD-10 Finland
Examination of ears and hearing
2.2
18.3
199
1023
R62.0
ICD-10 Finland
Delayed milestone
2.9
17.8
90
324
P07.0
ICD-10 Finland
Extremely low birth weight
+∞
17.6
17
*
ZXD10
NOMESCO Finland
Scheduled procedure
1.9
17.3
301
1827
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.3
16.7
139
637
P08.1
ICD-10 Finland
Other heavy for gestational age infants
+∞
16.5
16
*
RK312, ,
NOMESCO Finland
13.5
15.8
27
20
ZXE10
NOMESCO Finland
More than one and less than three hours
2.0
15.5
235
1353
FDE00
NOMESCO Finland
Closure of patent ductus arteriosus
157.9
15.3
16
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.2
15.0
143
692
R62.8
ICD-10 Finland
Other lack of expected normal physiological development
4.3
14.6
38
88
P22.8
ICD-10 Finland
Other respiratory distress of newborn
13.1
14.5
25
19
A03FA02
ATC
cisapride; oral, rectal
3.4
14.1
51
150
WX408
NOMESCO Finland
General anesthesy, balanced
1.9
13.9
254
1545
P28.4
ICD-10 Finland
Other apnoea of newborn
29.7
13.7
18
6
Z2221
NOMESCO Finland
Medical doctor
1.9
13.5
212
1229
RT150, ,
NOMESCO Finland
4.2
13.1
35
83
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
5.0
12.8
28
56
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.9
12.8
208
1215
ZXE00
NOMESCO Finland
One hour or less
1.7
12.6
315
2091
RK520, ,
NOMESCO Finland
15.2
12.4
20
13
J21.9
ICD-10 Finland
Acute bronchiolitis, unspecified
2.3
11.7
92
409
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
2.0
11.6
153
831
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
3.1
11.6
48
154
TJF80
NOMESCO Finland
Ostomy education
5.6
11.5
22
39
F98.2
ICD-10 Finland
Feeding disorder of infancy and childhood
4.3
11.5
30
70
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
3.8
11.4
35
92
6BB16, ,
NOMESCO Finland
22.5
11.4
16
7
137
Kela drug reimbursment
Uraemia requiring dialysis
5.8
11.3
21
36
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.6
11.3
68
267
WX732
NOMESCO Finland
High frequency respirator
117.8
11.3
12
*
H66.0
ICD-10 Finland
Acute suppurative otitis media
1.7
11.2
319
2179
Z01.8
ICD-10 Finland
Other specified special examinations
1.9
11.0
158
883
P52.0
ICD-10 Finland
Intraventricular (nontraumatic) haemorrhage, grade 1, of fetus and newborn
42.6
10.8
13
*
RS220, ,
NOMESCO Finland
3.6
10.8
35
96
P70.0
ICD-10 Finland
Syndrome of infant of mother with gestational diabetes
4.4
10.7
27
61
P59.9
ICD-10 Finland
Neonatal jaundice, unspecified
3.0
10.6
46
152
P52.2
ICD-10 Finland
Intraventricular (nontraumatic) haemorrhage, grade 3, and grade 4 of fetus and newborn
58.9
10.5
12
*
XA800
NOMESCO Finland
Neuropsychological investigation
2.2
10.4
89
410
KAC00
NOMESCO Finland
Nephrectomy
5.5
10.3
20
36
Z3231
NOMESCO Finland
Registered nurse
1.6
10.2
304
2088
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
4.9
10.1
22
44
G80.1
ICD-10 Finland
Spastic diplegic cerebral palsy
10.4
10.1
19
18
Z00.6
ICD-10 Finland
Examination for normal comparison and control in clinical research programme
10.4
10.1
19
18
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
2.2
10.0
88
411
Z94.0
ICD-10 Finland
Kidney transplant status
4.0
9.8
28
70
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
4.1
9.7
27
66
XKC03
NOMESCO Finland
Water cystometry
4.9
9.6
21
42
TJD20
NOMESCO Finland
Change of gastrostomy tube
4.4
9.6
24
54
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
2.2
9.4
81
374
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.4
9.3
64
268
P01.11
ICD-10 Finland
Fetus and newborn affected by premature rupture of membranes more than 7 days before delivery
+∞
9.3
9
*
P61.2
ICD-10 Finland
Anaemia of prematurity
+∞
9.3
9
*
ZXD05
NOMESCO Finland
Urgent procedure
1.8
9.2
168
1007
P02.1
ICD-10 Finland
Fetus and newborn affected by other forms of placental separation and haemorrhage
21.3
9.2
13
6
P03.4
ICD-10 Finland
Fetus and newborn affected by caesarean delivery
12.1
9.2
16
13
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
2.1
9.2
96
479
RL140, ,
NOMESCO Finland
3.7
9.2
29
78
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
4.6
8.9
21
45
J21.0
ICD-10 Finland
Acute bronchiolitis due to respiratory syncytial virus
2.5
8.8
58
239
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
4.2
8.7
23
54
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
2.0
8.7
100
517
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
8.6
229
1518
R03AK06
ATC
salmeterol and fluticasone; inhalant
2.1
8.6
89
443
ZX114
NOMESCO Finland
Intramuscular
3.5
8.5
29
82
ZXA10
NOMESCO Finland
Bilateral
1.8
8.5
141
821
TPH07
NOMESCO Finland
Cathetrisation of artery
2.1
8.4
88
439
K40.2
ICD-10 Finland
Bilateral inguinal hernia, without obstruction or gangrene
8.8
8.4
17
19
WX725
NOMESCO Finland
Noninvasive ventilation
3.3
8.4
32
98
J45.9
ICD-10 Finland
Asthma, unspecified
1.8
8.3
145
856
P36.3
ICD-10 Finland
Sepsis of newborn due to other and unspecified staphylococci
88.1
8.3
9
*
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
7.2
8.3
19
26
WW500
NOMESCO Finland
Blood transfusion
2.8
8.2
40
141
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.8
8.2
123
694
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
3.0
8.2
36
120
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.7
8.1
178
1120
H01AC01
ATC
somatropin; parenteral
2.7
8.1
45
170
R03BB04
ATC
tiotropium bromide; inhalant
4.4
8.0
20
45
J45.8
ICD-10 Finland
Mixed asthma
3.1
8.0
34
111
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
7.4
8.0
18
24
UGC02
NOMESCO Finland
Rigid bronchoscopy
3.9
8.0
23
58
Z2445
NOMESCO Finland
Psychologist
1.8
8.0
121
685
R03BA02
ATC
budesonide; inhalant
1.8
8.0
144
859
N04.80
ICD-10 Finland
Congenital nephrotic syndrome of the Finnish type
8.0
7.9
17
21
UDC00
NOMESCO Finland
Ear microscopy
2.0
7.8
91
472
P36.90
ICD-10 Finland
Suspected bacterial sepsis of newborn
3.6
7.8
25
68
XF400
NOMESCO Finland
ECG with 12 standard connections
1.7
7.6
154
948
P00.8
ICD-10 Finland
Fetus and newborn affected by other maternal conditions
14.7
7.6
12
8
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
2.2
7.6
62
281
P29.31
ICD-10 Finland
Persistent fetal circulation
11.6
7.4
13
11
P77
ICD-10 Finland
Necrotizing enterocolitis of fetus and newborn
78.3
7.3
8
*
R03AK08
ATC
formoterol and beclometasone; inhalant
3.7
7.3
23
62
WX704
NOMESCO Finland
Intubation
2.3
7.2
53
229
301
Kela drug reimbursment
Growth hormone
3.4
7.2
25
72
A11CC03
ATC
alfacalcidol; systemic
3.1
7.2
29
92
EMB30
NOMESCO Finland
Adenotomy
1.6
7.2
182
1187
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.6
7.1
213
1444
JF2AB
NOMESCO Finland
Colongraphy with X-ray
15.4
7.1
11
7
J21.90
ICD-10 Finland
Acute obstructive bronchitis in children
2.1
7.1
69
335
SPAT1229
SPAT
Assessment of need for aid
4.1
7.0
19
46
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.6
6.9
176
1147
ZXE20
NOMESCO Finland
More than three and less than five hours
1.9
6.9
97
536
G80.2
ICD-10 Finland
Spastic hemiplegic cerebral palsy
6.8
6.8
16
23
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.7
6.8
137
840
H66.9
ICD-10 Finland
Otitis media, unspecified
1.5
6.8
245
1728
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.2
6.8
59
274
A12AA04
ATC
calcium carbonate; oral
4.0
6.8
19
47
R50.9
ICD-10 Finland
Fever, unspecified
1.6
6.7
202
1369
RK410, ,
NOMESCO Finland
16.3
6.6
10
6
7AA02, ,
NOMESCO Finland
22.0
6.6
9
*
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
1.8
6.5
98
552
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.9
6.5
90
494
P21.1
ICD-10 Finland
Mild and moderate birth asphyxia
4.0
6.5
18
44
Z99.2
ICD-10 Finland
Dependence on renal dialysis
6.3
6.5
16
25
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.5
6.5
40
160
P21.0
ICD-10 Finland
Severe birth asphyxia
5.8
6.5
17
29
RS121, ,
NOMESCO Finland
3.4
6.4
22
63
F80.1
ICD-10 Finland
Expressive language disorder
2.4
6.4
42
173
RK310, ,
NOMESCO Finland
6.7
6.4
15
22
JDB10
NOMESCO Finland
Percutaneous gastrostomy
3.7
6.3
20
54
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
2.1
6.3
60
289
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
2.0
6.3
72
371
ZX108
NOMESCO Finland
Inhalation
3.5
6.3
21
59
A28
ICPC
Limited function/disability NOS
2.1
6.3
57
270
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
3.1
6.3
26
84
F83
ICD-10 Finland
Mixed specific developmental disorders
2.1
6.3
60
290
N18.8
ICD-10 Finland
Other chronic renal failure
4.1
6.3
17
41
WW200
NOMESCO Finland
Immunization
2.9
6.3
29
100
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
1.6
6.2
162
1060
J12.1
ICD-10 Finland
Respiratory syncytial virus pneumonia
8.0
6.2
13
16
H53.0
ICD-10 Finland
Amblyopia ex anopsia
2.5
6.2
38
152
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.6
6.2
138
870
Q21.00
ICD-10 Finland
Multiple ventricular septal defect
3.5
6.1
21
60
ZXA00
NOMESCO Finland
Right side
1.8
6.1
89
497
FM2CE, ,
NOMESCO Finland
1.9
6.1
78
418

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
26
78
3.30
7.04
3.0
2.3
—
—
—
0
0
212
1439
1.57
7.04
3.5
3.8
—
—
—
0
0
124
736
1.74
6.94
5.1
3.3
21.66
21.83
%
0.04
118
699
186
1231
1.60
6.86
3.3
3.7
—
—
—
0
0
198
1337
1.57
6.68
17.0
11.4
1.41
1.33
mmol/l
2.43
192
1279
37
141
2.61
6.61
4.9
4.4
24.29
23.97
umol/l
0.07
37
141
207
1430
1.54
6.27
22.4
9.6
7.38
7.41
ph
2.72
13
51
207
1430
1.54
6.27
22.5
9.6
5.14
4.99
kpa
2.44
201
1384
128
790
1.67
6.20
4.9
3.1
2.65
2.60
g/l
0.33
123
754
185
1253
1.55
6.11
22.0
9.5
—
—
—
0
0
189
1317
1.51
5.42
21.8
9.5
9.55
9.73
kpa
0.67
182
1275
133
872
1.57
5.02
16.5
13.4
0.80
0.81
mmol/l
0.58
127
845
29
115
2.50
4.84
3.4
3.4
17.84
17.79
%
0.03
21
71
134
890
1.55
4.77
5.0
3.1
13.59
13.97
umol/l
0.21
128
860
33
146
2.24
4.36
2.3
1.9
—
—
—
0
0
341
2731
1.36
4.32
24.0
13.1
1.24
1.23
mmol/l
0.29
327
2618
87
535
1.64
4.28
13.4
8.3
50.71
51.39
ng/l
0.08
87
523
126
847
1.52
4.24
21.8
14.1
5.68
5.13
mmol/l
1.17
121
834
136
932
1.49
4.17
2.5
5.1
1.80
1.76
mg/l
0.03
88
631
121
813
1.52
4.08
1.6
1.5
167.52
359.40
u/ml
2.05
109
771
352
2855
1.34
4.02
23.4
12.0
1.23
1.23
mmol/l
0.01
325
2654
17
58
2.88
3.80
1.0
1.0
—
—
—
0
0
62
361
1.72
3.75
1.7
1.3
—
—
—
0
0
45
239
1.87
3.69
16.6
9.8
23.05
22.95
mmol/l
0.10
45
230
10
20
4.89
3.59
1.1
1.5
—
—
—
0
0
270
2143
1.33
3.47
8.6
9.1
—
—
—
0
0
30
141
2.10
3.46
8.3
7.5
—
—
—
0
0
29
136
2.10
3.37
5.5
5.6
2.47
2.29
ug/l
0.18
29
136
180
1349
1.37
3.36
4.0
2.8
2.41
2.40
mmol/l
0.13
171
1239
251
1981
1.33
3.33
8.0
8.4
33.00
22.35
umol/l
2.16
230
1813
16
57
2.75
3.33
10.4
3.2
130.00
158.55
umol/l
0.59
11
27
103
700
1.49
3.30
1.5
1.4
20.39
18.64
nmol/l
0.56
87
629
140
1011
1.41
3.25
3.9
4.2
—
—
—
0
0
134
965
1.41
3.16
3.6
7.3
31.43
31.36
s
0.05
134
955
24
109
2.17
3.04
1.6
1.3
—
—
—
0
0
98
671
1.47
3.03
23.4
19.9
1.13
1.03
mg/l
1.71
98
660
169
1276
1.36
3.00
14.1
11.5
—
—
—
0
0
371
3118
1.28
2.99
10.7
7.5
5.91
5.91
mmol/l
0.00
350
2925
78
512
1.53
2.96
10.9
12.4
106.18
105.65
mmol/l
0.56
78
512
60
373
1.60
2.88
9.6
8.2
0.52
0.46
g/l
0.10
48
298
154
1155
1.36
2.85
6.0
3.9
7.38
7.39
ph
0.23
32
195
24
113
2.09
2.80
3.4
2.5
—
—
—
0
0
14
52
2.64
2.72
1.9
1.5
—
—
—
0
0
23
110
2.06
2.59
4.0
4.7
—
—
—
0
0
21
97
2.13
2.58
4.2
5.2
—
—
—
0
0
84
578
1.45
2.56
1.9
1.9
—
—
—
0
0
170
1317
1.31
2.52
10.7
9.9
23.56
23.48
mmol/l
0.21
170
1317
27
139
1.91
2.50
9.6
5.6
—
—
—
0
0
381
3263
1.24
2.47
7.5
5.6
141.86
119.53
u/l
3.51
368
3069
60
389
1.53
2.44
6.7
5.7
0.90
0.45
%
0.56
30
151
47
288
1.62
2.43
1.8
1.7
—
—
—
0
0
36
206
1.72
2.40
3.6
3.8
—
—
—
0
0
71
482
1.47
2.33
3.0
1.9
206.80
161.01
u/ml
0.41
34
224
86
608
1.41
2.28
3.7
5.3
66.08
64.44
e9/l
0.10
66
370
56
364
1.53
2.27
6.7
5.8
0.08
0.02
%
0.47
25
122
248
2042
1.25
2.25
3.6
3.5
—
—
—
0
0
69
470
1.46
2.24
1.5
1.4
547.71
16029154.62
pmol/l
0.50
62
418
679
6239
1.29
2.21
12.2
7.8
—
—
—
0
0
15
65
2.26
2.17
3.3
3.3
—
—
—
0
0
164
1290
1.29
2.17
6.2
3.6
6.74
6.92
e6/l
0.06
141
1152
178
1415
1.28
2.16
14.0
10.3
1.03
1.07
mmol/l
0.07
146
1120
22
112
1.93
2.13
10.6
7.5
1.54
1.46
mmol/l
0.07
12
53
178
1419
1.27
2.11
14.7
10.3
—
7.35
—
0
8
46
291
1.56
2.11
1.6
1.9
—
—
—
0
0
406
3540
1.22
2.11
10.7
11.0
0.00
0.01
e9/l
0.80
332
2726
55
363
1.50
2.09
6.2
5.1
0.65
0.32
%
0.48
26
139
171
1366
1.27
2.00
13.0
10.2
5.19
5.15
kpa
0.11
165
1339
97
717
1.35
1.99
7.7
8.0
5.98
6.17
umol/l
0.10
83
596
177
1422
1.26
1.97
14.1
10.3
5.69
5.81
kpa
1.30
172
1388
21
109
1.89
1.94
9.6
7.9
—
—
—
0
0
55
370
1.47
1.93
7.1
5.8
0.12
0.05
%
0.35
26
132
5
11
4.42
1.89
3.8
3.9
0.42
0.49
umol/l
—
5
11
106
803
1.32
1.86
2.2
1.8
—
—
—
0
0
42
269
1.54
1.86
6.1
7.2
203.49
226.49
ng/l
0.10
35
246
51
342
1.47
1.82
3.8
2.2
72.52
82.04
u/ml
—
5
20
109
833
1.31
1.80
3.5
2.7
320.38
348.65
nmol/l
0.75
104
799
123
956
1.29
1.79
2.5
1.7
—
—
—
0
0
273
2327
1.20
1.72
5.6
3.5
69.84
67.20
nmol/l
0.89
259
2210
6
18
3.25
1.69
2.2
1.6
236.83
149.94
nmol/l
—
6
18
76
558
1.35
1.66
2.4
2.2
5.92
5.98
u/l
0.02
57
359
237
2003
1.20
1.62
7.2
4.4
256.16
34.56
e6/l
0.48
186
1495
7
25
2.73
1.59
1.7
1.2
—
—
—
0
0
157
1277
1.24
1.57
5.4
3.4
552.80
601.96
mosm/kgh2o
1.38
130
1118
66
482
1.35
1.51
2.5
2.2
8.67
6.93
iu/l
0.45
50
315
413
3685
1.17
1.47
9.5
9.6
8.22
8.24
%
0.03
390
3537
15
77
1.90
1.47
17.7
8.8
—
—
—
0
0
433
3879
1.17
1.47
9.8
10.1
0.20
0.22
e9/l
1.23
383
3308
46
318
1.43
1.45
10.7
14.1
-0.47
-0.29
mmol/l
0.12
36
245
220
1868
1.19
1.42
6.6
4.3
0.50
0.24
e6/l
0.39
169
1376
39
263
1.46
1.40
9.3
15.7
0.72
0.64
%
0.79
39
263
7
28
2.43
1.39
2.7
1.5
—
—
—
0
0
409
3658
1.16
1.39
9.2
9.5
2.79
3.23
%
3.17
390
3516
25
371
0.64
1.38
1.2
1.1
5.67
10.47
u/ml
0.78
14
222
24
146
1.61
1.36
1.7
1.3
342.88
384.30
ug/g
0.47
16
69
79
961
0.78
1.36
1.5
1.9
—
—
—
0
0
9
40
2.19
1.36
1.2
1.2
—
—
—
0
0
45
593
0.72
1.34
1.2
1.2
4.95
3.23
u/ml
0.29
36
430
156
1291
1.21
1.33
6.6
4.9
1.03
1.10
inr
2.84
52
375
593
5470
1.17
1.32
20.3
12.2
3.97
3.92
mmol/l
3.04
578
5287
49
350
1.38
1.31
4.0
2.2
—
—
—
0
0
419
3770
1.15
1.28
9.3
9.3
0.04
0.04
e9/l
0.07
360
3158
6
24
2.43
1.25
1.0
1.0
—
—
—
0
0
147
1220
1.20
1.22
5.3
3.8
2.89
3.34
e6/l
0.16
94
692
396
3558
1.15
1.22
9.2
9.7
0.59
0.62
%
0.37
379
3419
418
3770
1.15
1.21
9.3
9.3
0.60
0.56
e9/l
2.00
359
3158
140
1158
1.21
1.20
1.8
1.5
103.18
98.15
pmol/l
0.47
63
624
418
3773
1.15
1.19
9.0
9.1
47.68
49.05
%
1.30
398
3638
52
656
0.75
1.19
1.2
1.2
3.36
3.50
u/ml
0.02
40
448
592
5478
1.16
1.19
20.3
12.3
139.41
139.44
mmol/l
0.12
580
5320
21
310
0.65
1.16
1.0
1.0
—
—
—
0
0
0
34
0.00
1.15
0.0
2.0
—
1.71
—
0
25
425
3847
1.14
1.15
9.1
9.3
36.87
35.60
%
1.26
406
3706
16
92
1.70
1.14
7.2
11.4
10.33
9.22
mg/l
0.30
16
86
23
331
0.66
1.14
1.1
1.1
2.09
0.40
u/ml
0.37
12
150
143
1193
1.19
1.13
5.1
3.7
0.85
0.96
e6/l
0.14
89
664
120
1362
0.83
1.12
3.5
3.2
72.72
112.44
ug/g
2.02
97
1065
33
442
0.71
1.12
1.5
1.5
—
—
—
0
0
8
39
2.00
1.11
1.4
1.2
—
—
—
0
0
34
236
1.41
1.10
6.2
4.6
—
—
—
0
0
12
64
1.83
1.08
2.1
2.0
—
—
—
0
0
25
164
1.49
1.07
2.2
2.7
—
—
—
0
0
151
1273
1.18
1.06
4.7
2.9
—
—
—
0
0
84
982
0.81
1.06
1.5
1.9
—
—
—
0
0
83
971
0.81
1.05
1.5
1.9
—
—
—
0
0
264
2327
1.15
1.04
8.4
5.2
47.38
60.71
e6/l
0.30
190
1560
16
95
1.64
1.03
5.4
3.2
—
—
—
0
0
84
979
0.81
1.03
1.5
1.9
—
—
—
0
0
110
1248
0.83
1.03
1.7
1.8
—
—
—
0
0
15
88
1.66
1.01
2.9
2.2
—
—
—
0
0
77
903
0.81
1.00
1.5
1.9
—
—
—
0
0
17
253
0.64
1.00
1.1
1.1
—
—
—
0
0
63
755
0.79
1.00
1.2
1.2
—
50.05
—
0
8
445
4067
1.13
0.99
11.6
10.9
3.44
3.46
e9/l
0.08
379
3393
0
28
0.00
0.98
0.0
1.2
—
5.31
—
0
22
170
1458
1.16
0.98
3.8
2.4
—
—
—
0
0
23
152
1.48
0.97
5.8
4.5
432.83
436.58
umol/l
0.03
23
144
21
296
0.68
0.96
1.1
1.1
4.98
8.21
u/ml
—
5
35
50
611
0.78
0.94
1.1
1.2
5.52
6.01
u/ml
0.10
36
445
41
303
1.33
0.93
1.4
1.6
1432.96
1018.80
nmol/l
1.95
33
236
31
405
0.73
0.93
1.1
1.1
7.01
6.60
u/ml
0.03
21
263
10
53
1.84
0.93
1.1
1.3
—
—
—
0
0
216
1895
1.14
0.91
6.6
4.2
—
—
—
0
0
49
597
0.78
0.90
1.1
1.2
0.42
1.11
u/ml
2.09
32
413
66
775
0.81
0.89
1.5
2.0
—
—
—
0
0
425
3891
1.12
0.88
9.3
9.3
2.52
2.37
e9/l
1.41
375
3366
646
6063
1.14
0.88
19.9
15.0
13.61
13.27
%
1.81
631
5946
15
92
1.59
0.87
2.3
4.1
3.62
4.33
%
—
5
34
8
42
1.85
0.87
1.0
1.1
—
—
—
0
0
12
70
1.67
0.84
1.2
1.1
—
—
—
0
0
49
378
1.27
0.84
1.8
1.4
—
—
—
0
0
13
196
0.64
0.84
1.9
1.7
—
—
—
0
0
14
207
0.65
0.83
1.1
1.3
1.86
20.50
u/ml
—
9
166
16
102
1.53
0.81
1.1
1.1
—
—
—
0
0
54
424
1.25
0.81
5.6
3.8
—
—
—
0
0
0
23
0.00
0.79
0.0
1.2
—
95.70
—
0
23
0
27
0.00
0.76
0.0
3.3
—
0.28
—
0
27
57
667
0.82
0.76
1.7
2.4
—
—
—
0
0
389
3565
1.11
0.76
10.4
10.0
—
—
—
0
0
348
3173
1.11
0.75
4.0
3.2
51.67
55.17
ug/l
0.16
333
3016
18
121
1.45
0.73
1.7
1.8
2.71
4.56
iu/l
—
8
43
13
81
1.56
0.73
2.0
1.8
—
—
—
0
0
5
25
1.94
0.71
1.4
4.8
13.40
25.04
u/l
—
5
25
7
39
1.75
0.71
22.1
11.7
708.57
699.54
nmol/l
—
7
39
48
379
1.24
0.70
1.0
1.0
9.54
8.69
mu/l
0.32
43
329
34
258
1.29
0.69
6.3
3.5
—
—
—
0
0
7
41
1.66
0.68
1.0
1.0
—
—
—
0
0
183
1621
1.12
0.67
3.7
3.2
2.86
2.67
mg/l
0.62
167
1455
222
1988
1.11
0.67
1.6
1.6
—
—
—
0
0
10
60
1.62
0.65
19.8
10.7
1.24
1.23
mmol/l
—
10
55
280
2546
1.10
0.62
7.3
4.9
0.00
0.00
estimate
-0.00
51
461
110
1193
0.88
0.62
1.3
1.2
—
—
—
0
0
5
29
1.67
0.61
2.8
1.2
—
—
—
0
0
161
1424
1.12
0.61
5.9
4.7
8.21
8.73
mmol/l
0.44
153
1357
9
135
0.64
0.61
1.3
1.9
—
—
—
0
0
8
49
1.59
0.61
1.4
1.5
—
—
—
0
0
8
49
1.59
0.61
1.4
1.5
—
—
—
0
0
8
49
1.59
0.61
1.4
1.5
—
—
—
0
0
0
19
0.00
0.60
0.0
2.5
—
—
—
0
0
0
19
0.00
0.60
0.0
1.5
—
—
—
0
0
0
20
0.00
0.60
0.0
3.5
—
13.70
—
0
20
0
20
0.00
0.60
0.0
3.4
—
—
—
0
0
37
290
1.25
0.60
1.0
1.0
3.03
3.30
kpa
0.64
31
244
19
135
1.37
0.60
1.8
1.3
—
—
—
0
0
25
186
1.31
0.59
10.3
19.4
—
—
—
0
0
72
800
0.86
0.57
1.7
1.6
564.71
529.54
titre
0.04
17
130
6
34
1.71
0.57
1.5
1.2
—
—
—
0
0
8
53
1.47
0.56
1.1
1.0
—
—
—
0
0
280
2558
1.09
0.56
5.3
3.4
0.00
0.00
estimate
-0.00
50
452
37
293
1.23
0.56
1.0
1.0
—
—
—
0
0
37
293
1.23
0.56
1.0
1.0
7.37
7.24
kpa
0.15
31
247
37
293
1.23
0.56
1.0
1.0
-1.25
-2.53
mmol/l
—
10
68
38
302
1.23
0.55
1.1
1.3
266.80
225.27
miu/ml
0.33
19
131
30
232
1.26
0.55
13.6
18.0
0.73
0.76
%
0.16
30
232
20
146
1.34
0.54
2.1
4.4
—
—
—
0
0
15
197
0.73
0.52
1.9
5.2
—
—
—
0
0
79
676
1.15
0.52
2.8
2.4
—
—
—
0
0
18
229
0.76
0.51
1.4
1.2
—
—
—
0
0
6
39
1.49
0.51
1.3
1.2
—
—
—
0
0
174
1568
1.10
0.48
3.8
5.2
34.35
34.09
u/l
0.04
169
1507
26
202
1.26
0.47
1.3
1.2
—
—
—
0
0
21
159
1.29
0.46
1.3
1.3
—
—
—
0
0
278
2559
1.08
0.46
5.4
3.4
0.00
0.00
estimate
-0.00
52
452
7
47
1.45
0.46
1.1
1.3
—
—
—
0
0
142
1271
1.10
0.45
6.4
3.4
0.00
0.00
estimate
-0.00
48
432
52
579
0.86
0.45
1.2
1.2
2.54
8.14
u/ml
1.10
17
161
545
5145
1.08
0.45
4.2
3.7
2.09
1.99
mu/l
0.93
510
4856
39
444
0.84
0.44
1.7
2.5
—
—
—
0
0
61
520
1.15
0.44
1.5
1.8
—
—
—
0
0
279
2835
0.93
0.44
1.7
1.8
3.95
3.44
u/ml
0.12
56
522
15
190
0.76
0.43
1.3
1.2
1.23
2.17
u/ml
—
10
132
755
7232
1.12
0.42
20.5
15.2
85.87
85.97
fl
0.19
741
7111
25
197
1.24
0.42
1.4
1.9
—
—
—
0
0
8
56
1.39
0.41
2.3
2.0
0.90
0.77
ug/l
—
8
47
0
15
0.00
0.41
0.0
2.4
—
—
—
0
0
0
16
0.00
0.41
0.0
7.1
—
—
—
0
0
600
5694
1.07
0.41
10.1
8.7
27.02
25.11
u/l
0.70
581
5501
14
102
1.34
0.40
1.1
1.3
10.17
2.97
u/ml
—
6
60
756
7245
1.12
0.40
20.5
15.3
7.01
6.97
e9/l
0.12
726
6867
755
7235
1.12
0.40
20.5
15.2
28.90
28.89
pg
0.04
741
7116
755
7236
1.12
0.39
20.5
15.2
4.66
4.62
e12/l
1.33
725
6853
754
7227
1.11
0.38
21.0
16.2
39.84
39.59
%
0.72
724
6928
29
235
1.20
0.38
1.4
1.2
—
—
—
0
0
5
35
1.39
0.38
1.0
1.1
—
—
nmol/l
—
0
0
18
138
1.27
0.38
4.4
4.5
51.39
51.19
%
0.02
18
138
29
236
1.20
0.37
1.3
1.2
—
—
—
0
0
109
975
1.10
0.37
1.5
1.6
—
—
—
0
0
15
185
0.78
0.37
2.7
2.0
—
—
—
0
0
88
779
1.11
0.36
2.6
2.2
12.16
56.90
ng/l
2.14
44
242
755
7242
1.11
0.35
20.8
15.6
134.31
133.06
g/l
1.49
742
7127
6
41
1.42
0.35
1.2
1.0
—
19.63
—
0
11
6
41
1.42
0.35
1.0
1.1
—
78.50
ng/l
—
0
8
5
78
0.62
0.35
7.6
5.3
—
98.09
—
0
9
39
433
0.87
0.35
1.7
1.4
—
—
—
0
0
13
162
0.77
0.35
1.5
1.2
—
0.21
—
0
9
57
616
0.89
0.34
1.2
1.2
11.35
25.92
iu/ml
0.81
11
124
197
2007
0.94
0.33
2.1
2.1
—
—
—
0
0
356
3561
0.95
0.33
6.7
3.8
538.17
226.68
e6/l
0.25
12
47
658
6284
1.07
0.32
17.9
14.2
335.70
334.91
g/l
1.29
650
6211
753
7228
1.10
0.31
20.6
15.4
276.48
272.21
e9/l
0.90
725
6867
7
95
0.71
0.31
1.1
1.1
—
—
—
0
0
18
143
1.22
0.30
1.2
1.3
—
—
—
0
0
13
158
0.79
0.29
1.9
2.3
—
66.00
—
0
20
17
135
1.22
0.28
4.2
4.0
3.49
3.38
e9/l
0.10
17
135
319
3187
0.95
0.28
3.4
2.5
1.33
1.40
mmol/l
2.64
299
3015
8
61
1.27
0.28
2.8
2.6
41000.00
40327.87
ug/l
—
8
61
108
981
1.08
0.27
2.0
1.7
—
—
—
0
0
43
373
1.12
0.27
1.2
1.2
—
—
—
0
0
127
1162
1.07
0.27
1.7
1.6
—
—
—
0
0
8
65
1.19
0.26
1.6
1.8
—
—
—
0
0
10
123
0.79
0.25
1.1
1.3
4.65
7.05
u/ml
—
10
107
236
2206
1.05
0.25
4.8
3.1
6.17
6.27
ph
0.29
21
253
330
3283
0.96
0.24
3.6
2.7
4.20
4.25
mmol/l
0.41
311
3128
22
184
1.16
0.23
1.2
1.1
—
—
—
0
0
7
92
0.74
0.22
1.7
1.6
—
—
—
0
0
13
152
0.83
0.22
1.8
2.0
—
—
—
0
0
98
896
1.07
0.22
1.7
1.9
1.35
1.20
mmol/l
0.53
91
828
323
3209
0.96
0.22
3.4
2.5
2.59
2.57
mmol/l
0.18
303
3019
15
172
0.84
0.21
1.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
3.9
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
157
1459
1.05
0.21
4.9
3.2
—
—
—
0
0
0
12
0.00
0.21
0.0
2.1
—
—
—
0
0
6
46
1.27
0.20
1.2
1.1
—
—
—
0
0
132
1336
0.95
0.20
1.7
1.7
—
—
—
0
0
322
3049
1.04
0.19
3.4
2.5
1.15
1.08
mmol/l
1.19
309
2891
35
308
1.11
0.19
1.6
1.4
—
—
—
0
0
17
142
1.16
0.18
2.2
1.5
—
—
—
0
0
12
97
1.20
0.18
1.1
1.1
—
—
—
0
0
27
235
1.12
0.17
5.8
5.4
18.10
12.12
umol/l
0.65
27
203
26
280
0.90
0.17
1.2
1.2
—
—
—
0
0
14
158
0.86
0.17
1.5
1.7
—
—
—
0
0
657
6310
1.04
0.17
15.0
10.6
20.88
23.08
mg/l
0.99
477
4253
5
67
0.72
0.17
1.2
1.6
12.46
8.73
umol/l
—
5
67
27
289
0.90
0.16
1.0
1.1
—
—
—
0
0
8
69
1.12
0.16
2.1
2.7
—
274.26
—
0
19
384
3659
1.03
0.15
6.4
4.2
—
—
—
0
0
6
78
0.74
0.15
1.8
1.2
—
—
—
0
0
35
313
1.09
0.15
1.3
1.2
—
—
—
0
0
9
80
1.09
0.14
8.6
5.8
—
—
—
0
0
239
2263
1.03
0.14
2.6
2.0
—
—
—
0
0
14
154
0.88
0.13
1.1
1.8
—
—
—
0
0
33
343
0.93
0.12
1.0
1.1
—
—
—
0
0
18
157
1.11
0.11
1.2
1.2
—
—
—
0
0
61
564
1.05
0.11
1.4
1.3
288.78
152.43
iu/ml
0.85
18
179
55
507
1.05
0.11
1.4
1.4
—
—
—
0
0
12
102
1.14
0.10
1.0
1.0
—
—
—
0
0
23
205
1.09
0.10
11.4
18.1
—
—
—
0
0
24
251
0.92
0.10
1.7
4.2
3.14
3.29
mmol/l
0.36
24
241
211
2007
1.02
0.10
1.7
1.8
—
—
—
0
0
5
45
1.08
0.09
3.2
2.8
3.58
3.82
mmol/l
—
5
45
5
45
1.08
0.09
1.0
1.0
—
—
—
0
0
5
45
1.08
0.09
1.0
1.3
—
—
—
0
0
5
46
1.05
0.09
1.6
2.2
—
—
—
0
0
5
46
1.05
0.09
1.2
1.2
207.20
252.77
iu/ml
—
5
46
5
46
1.05
0.09
3.2
2.7
21.54
18.81
umol/l
—
5
46
5
47
1.03
0.09
19.2
3.8
—
—
—
0
0
269
2644
0.98
0.09
1.8
1.7
1.54
1.52
g/l
0.13
142
1392
286
2809
0.98
0.09
4.5
4.5
29.26
24.88
u/l
1.14
272
2704
70
655
1.04
0.08
3.3
3.9
1905.20
1350.32
ng/l
0.21
35
357
6
57
1.02
0.08
1.0
1.1
247.00
281.89
mg/l
—
6
57
6
57
1.02
0.08
1.0
1.2
—
—
—
0
0
5
60
0.81
0.08
2.8
1.6
—
—
—
0
0
355
3476
0.98
0.08
2.6
2.1
5.36
5.27
mmol/l
0.66
315
3193
5
62
0.78
0.08
1.0
1.2
—
—
—
0
0
407
3910
1.02
0.07
5.4
4.2
6.88
7.17
mm/h
0.31
382
3623
8
74
1.05
0.07
1.0
1.1
—
—
—
0
0
8
88
0.88
0.07
1.0
1.1
—
—
—
0
0
296
2839
1.02
0.06
3.8
2.9
35.43
35.76
mmol/mol
0.21
276
2678
79
746
1.03
0.06
3.1
2.3
11516.60
6286.58
u/l
0.49
21
202
481
4637
1.01
0.05
3.7
3.3
14.50
14.39
pmol/l
0.46
434
4135
28
260
1.04
0.04
1.8
4.2
401.18
400.45
mg/l
0.00
28
255
22
206
1.04
0.01
3.0
3.2
751.50
532.20
e6/l
0.97
22
141
11
113
0.94
0.01
1.1
1.3
2.60
16.38
u/ml
2.25
11
101
14
142
0.95
0.01
1.1
1.1
—
—
—
0
0
16
160
0.97
0.00
1.4
4.0
—
—
—
0
0
25
240
1.01
0.00
1.7
4.5
—
—
—
0
0
22
217
0.98
0.00
3.0
3.3
2.09
1.45
e9/l
1.09
22
154
14
132
1.03
0.00
1.6
1.7
—
—
—
0
0
133
1293
1.00
0.00
5.1
2.8
1.02
1.02
kg/l
0.93
26
239
13
126
1.00
0.00
1.5
1.5
—
—
—
0
0
13
126
1.00
0.00
1.5
1.5
—
—
—
0
0
26
249
1.01
0.00
1.8
4.4
47.60
10.83
e6/l
0.41
20
179
14
133
1.02
0.00
10.6
24.9
12.29
11.27
%
0.58
14
133
14
133
1.02
0.00
1.1
1.1
—
—
—
0
0
29
281
1.00
0.00
1.5
2.1
—
—
—
0
0
13
129
0.98
0.00
1.6
1.5
—
—
—
0
0
22
208
1.03
0.00
3.0
3.2
0.22
0.18
e9/l
0.36
22
142
31
301
1.00
0.00
1.6
1.6
—
—
—
0
0
14
131
1.04
0.00
2.8
2.5
1.18
2.07
mmol/l
—
9
105
18
172
1.01
0.00
1.5
1.6
10.93
6.14
ug/l
0.40
18
157
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
8
84
0.92
-0.00
1.1
1.1
—
—
—
0
0
5
58
0.83
-0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
5.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.1
—
—
—
0
0
7
77
0.88
-0.00
1.9
1.9
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
35.60
—
0
5
0
5
0.00
-0.00
0.0
2.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
243.40
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.2
—
—
—
0
0
8
80
0.97
-0.00
1.1
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
80
0.97
-0.00
1.5
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
37.79
—
0
7
0
5
0.00
-0.00
0.0
1.6
—
1118.60
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
53.69
—
0
5
6
67
0.87
-0.00
2.3
2.9
7.00
49.72
u/ml
—
6
58
5
49
0.99
-0.00
1.4
1.1
—
—
—
0
0
8
84
0.92
-0.00
1.1
1.1
191.25
202.07
mg/l
—
8
78

Mortality – FinRegistry

Association

Association between endpoint P16_DISORD_RELATED_GESTATION_LOW_BIRTHWGHTT_NECIFIED and mortality.

Females

Parameter HR [95% CI] p-value
P16_DISORD_RELATED_GESTATION_LOW_BIRTHWGHTT_NECIFIED 3.516 [2.95, 4.19] < 0.001
Birth year 0.994 [0.99, 1.0] 0.206

During the follow-up period (1.1.1998 — 31.12.2019), 183 out of 21756 females with P16_DISORD_RELATED_GESTATION_LOW_BIRTHWGHTT_NECIFIED died.

Males

Parameter HR [95% CI] p-value
P16_DISORD_RELATED_GESTATION_LOW_BIRTHWGHTT_NECIFIED 2.27 [1.96, 2.63] < 0.001
Birth year 0.987 [0.98, 1.0] 0.007

During the follow-up period (1.1.1998 — 31.12.2019), 236 out of 25440 males with P16_DISORD_RELATED_GESTATION_LOW_BIRTHWGHTT_NECIFIED died.

Mortality risk

Mortality risk for people of age

years, who have P16_DISORD_RELATED_GESTATION_LOW_BIRTHWGHTT_NECIFIED.

N-year risk Females Males
1 0.389% 0.476%
5 2.249% 2.702%
10 5.077% 6.732%
15 10.073% 12.848%
20 16.689% 20.649%

Relationships between endpoints

Index endpoint: P16_DISORD_RELATED_GESTATION_LOW_BIRTHWGHTT_NECIFIED – Disorders related to short gestation and low birth weight, not elsewhere classified

GWS hits: 2

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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