Intracranial nontraumatic haemorrhage of fetus and newborn

P16_INTRACR_NONTRAU_HAEMORRHAGE_FETUS_NEWBO

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule None	519972
2. Check conditions None	519972
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — P52 Cause of death: ICD-10 — P52 2 out of 7 registries used, show all original rules.	50
4. Check minimum number of events None	50
5. Include endpoints None	50
6. Filter based on genotype QC (FinnGen only)	48

Control definitions (FinnGen only)

Control exclude: P16_HAEMORRHAGIC_HAEMATOL_DISORD_FETUS_NEWBO

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF4
Parent code in ICD-10: P[5-6]
Name in latin: Haemorrhagia intracranialis non traumatica fetus sive neonati

NAME	P16_INTRACR_NONTRAU_HAEMORRHAGE_FETUS_NEWBO
CONTROL_EXCLUDE	P16_HAEMORRHAGIC_HAEMATOL_DISORD_FETUS_NEWBO
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	P52
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	P52
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Intracranial nontraumatic haemorrhage of fetus and newborn based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	2780	1110	1670
Only index persons	1118	439	679
Unadjusted period prevalence (%)
Whole population	0.04	0.03	0.05
Only index persons	0.02	0.02	0.03
Median age at first event (years)
Whole population	-	0.00	0.00
Only index persons	0.00	0.00	0.00

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	48	27	21
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	0.00	0.00	0.00

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
50: Matched controls
500

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

Z87.6

ICD-10 Finland

Personal history of certain conditions arising in the perinatal period

46.6

25.6

P52.0

ICD-10 Finland

Intraventricular (nontraumatic) haemorrhage, grade 1, of fetus and newborn

+∞

20.1

P52.2

ICD-10 Finland

Intraventricular (nontraumatic) haemorrhage, grade 3, and grade 4 of fetus and newborn

+∞

16.6

P07.2

ICD-10 Finland

Extreme immaturity

+∞

16.6

P27.1

ICD-10 Finland

Bronchopulmonary dysplasia originating in the perinatal period

+∞

15.4

P07.3

ICD-10 Finland

Other preterm infants

26.7

14.5

P22.0

ICD-10 Finland

Respiratory distress syndrome of newborn

189.4

14.2

602

Kela drug reimbursment

Children's severe malnutrition

19.6

14.2

R4110

NOMESCO Finland

Physiotherapy

8.5

13.0

AA7AA

NOMESCO Finland

Liquor cerebri shunt X-ray examinatin without contrast

137.7

10.9

Z50.8

ICD-10 Finland

Care involving use of other rehabilitation procedures

12.7

9.9

Z2446

NOMESCO Finland

Social worker

6.5

9.8

G91.1

ICD-10 Finland

Obstructive hydrocephalus

122.2

9.8

AAF05

NOMESCO Finland

Ventriculoperitoneal shunt

122.2

9.8

AAF20

NOMESCO Finland

Revision of shunt of ventricle of brain

122.2

9.8

P59.0

ICD-10 Finland

Neonatal jaundice associated with preterm delivery

+∞

9.7

H35.1

ICD-10 Finland

Retinopathy of prematurity

+∞

9.7

AA5HE

NOMESCO Finland

Brain ultrasound examination in a child

11.1

9.2

G40.9

ICD-10 Finland

Epilepsy, unspecified

61.1

9.0

AA1CG

NOMESCO Finland

Extensive MRI examination of brain with high intensity magnet

9.1

8.9

AA1AG

NOMESCO Finland

Short MRI examination of brain with median intensity magnet

107.4

8.7

R1230

NOMESCO Finland

Neuropsychological evaluation of need and possibilities to rehabilitation

10.6

8.6

P52.4

ICD-10 Finland

Intracerebral (nontraumatic) haemorrhage of fetus and newborn

+∞

8.6

F82

ICD-10 Finland

Specific developmental disorder of motor function

17.0

8.4

WX882

NOMESCO Finland

High dependency care

5.7

7.9

N05BA01

ATC

diazepam; systemic, rectal

17.0

7.9

G91.0

ICD-10 Finland

Communicating hydrocephalus

93.4

7.6

WX730

NOMESCO Finland

Conventional respirator

93.4

7.6

P07.02

ICD-10 Finland

Extremely low birth weight 750-999 g

+∞

7.5

R2130

NOMESCO Finland

Counselling and guidance which enhance independent living

5.2

7.3

P29.30

ICD-10 Finland

Delayed closure of the ductus arteriosus

46.5

7.0

ZXD05

NOMESCO Finland

Urgent procedure

5.0

6.9

ZXE10

NOMESCO Finland

More than one and less than three hours

4.6

6.7

101

P07.10

ICD-10 Finland

Other low birth weight 1000-1499 g

79.6

6.6

R03BB01

ATC

ipratropium bromide; inhalant

79.6

6.6

GD1UA

NOMESCO Finland

Thorax X-ray examination outside radiological department

5.0

6.5

WX408

NOMESCO Finland

General anesthesy, balanced

4.5

6.5

117

Z2221

NOMESCO Finland

Medical doctor

4.6

6.5

TPH04

NOMESCO Finland

Cathetrisation of vein

5.1

6.5

WW804

NOMESCO Finland

Transfer from treating institution to higher-Level care, accompanied by doctor

31.0

6.4

P52.1

ICD-10 Finland

Intraventricular (nontraumatic) haemorrhage, grade 2, of fetus and newborn

+∞

6.4

G91.9

ICD-10 Finland

Hydrocephalus, unspecified

+∞

6.4

Z01.0

ICD-10 Finland

Examination of eyes and vision

4.7

6.4

Z3226

NOMESCO Finland

Physiotherapist

4.4

6.4

AA1AD

NOMESCO Finland

CT of head and brain

10.1

6.3

111

Kela drug reimbursment

Epilepsy and comparable convulsive disorders

8.4

6.0

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3016914) Bacteria identified in Cerebral spinal fluid by Culture

12.13

5.83

4.2

1.0

—

(3033386) Bacteria [Presence] in Cerebral spinal fluid by Light microscopy

10.66

5.02

3.7

1.2

—

(3019473) Protein [Mass/volume] in Cerebral spinal fluid

6.82

4.98

4.4

8.4

651.33

341.64

mg/l

0.64

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

4.23

4.63

2.6

1.2

100.14

101.36

pmol/l

—

(3044290) Cell count panel - Cerebral spinal fluid

6.39

4.45

4.8

8.9

—

(3022313) Gas panel - Capillary blood

125

3.25

4.04

27.5

9.1

—

(3023368) Bacteria identified in Blood by Culture

3.46

3.92

7.8

4.7

—

(3023410) Appearance of Cerebral spinal fluid

5.67

3.79

4.8

8.9

—

(3020393) Adenovirus Ag [Presence] in Stool

7.09

3.66

2.3

2.2

—

(3020044) Glucose [Moles/volume] in Cerebral spinal fluid

5.40

3.66

4.5

8.4

2.66

3.27

mmol/l

—

(43055554) Base excess.100% oxygenated [Moles/volume] standard in Capillary blood by calculation

140

3.02

3.58

28.4

9.1

1.23

1.01

mmol/l

0.22

105

(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma

4.03

3.47

2.9

2.1

713.46

204.55

u/l

0.85

(3004490) Bicarbonate [Moles/volume] standard in Capillary blood

134

2.96

3.46

28.8

9.0

23.73

24.16

mmol/l

0.35

134

(3046896) Herpes virus 6 DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

9.52

3.36

2.5

1.0

—

(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection

6.12

3.34

3.4

2.4

—

(3005757) Coagulation factor V activity actual/normal in Platelet poor plasma by Coagulation assay

7.19

3.30

1.3

9.4

104.71

84.82

—

(3016018) Differential panel - Cerebral spinal fluid

5.73

3.20

4.4

7.5

—

(3008733) Herpes simplex virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

8.32

3.14

2.7

1.0

—

(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

8.32

3.14

2.5

1.0

—

(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum

6.58

3.14

1.0

1.2

—

(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection

5.38

3.06

3.4

2.4

—

(40763324) Parainfluenza virus 1 RNA [Presence] in Isolate by NAA with probe detection

4.75

3.05

1.8

2.4

—

(40763470) Parainfluenza virus 4 RNA [Presence] in Isolate by NAA with probe detection

4.75

3.05

1.8

2.4

—

(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum

6.06

2.98

1.9

2.2

—

(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection

4.53

2.94

2.0

2.3

—

(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection

4.53

2.94

2.0

2.3

—

(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay

4.53

2.94

2.4

1.4

—

(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection

4.53

2.94

3.3

2.3

—

(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay

4.53

2.94

2.4

1.4

—

(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection

5.07

2.93

3.9

2.4

—

(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method

3.15

2.92

4.9

10.4

78.29

86.80

0.60

(3016407) Fibrinogen [Mass/volume] in Platelet poor plasma by Coagulation assay

3.52

2.87

5.3

12.6

2.11

2.66

g/l

1.39

(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection

4.33

2.83

3.3

2.4

—

(3020287) Protein C actual/normal in Platelet poor plasma by Coagulation assay

9.07

2.81

1.2

1.8

67.40

91.17

—

(3005715) Vancomycin [Mass/volume] in Serum or Plasma

9.07

2.81

4.0

10.2

21.04

10.47

mg/l

—

(3019250) Coagulation factor VIII activity actual/normal in Platelet poor plasma by Coagulation assay

3.43

2.79

5.5

11.8

101.83

167.14

4.17

(3042936) Bacteria identified in Isolate by Culture

3.52

2.70

2.4

1.5

—

(3013005) Retinol [Moles/volume] in Serum or Plasma

6.02

2.62

4.0

4.5

1.43

1.45

umol/l

—

(3022229) Phosphate [Moles/volume] in Urine

7.77

2.61

3.2

5.6

21.26

13.81

mmol/l

—

(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method

7.77

2.61

1.2

1.3

—

(3013512) EKG study

3.83

2.54

1.7

2.1

—

(3024891) Influenza virus A+B Ag [Presence] in Specimen

3.41

2.45

2.4

1.3

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

2.84

2.36

3.5

2.1

—

(3009466) Valproate [Moles/volume] in Serum or Plasma

6.02

2.27

5.2

3.4

476.20

415.44

umol/l

—

(3000494) Fungus identified in Specimen by Culture

3.31

2.20

1.9

1.5

—

(3018133) Calcium [Moles/volume] in Urine

5.41

2.12

4.4

4.3

4.23

2.64

mmol/l

—

(3044640) Blood type and Crossmatch panel - Blood

2.40

2.10

4.8

4.6

—

(3007853) Bacteria identified in Skin by Aerobe culture

2.63

2.05

3.3

1.6

—

(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay

3.00

1.98

1.1

2.2

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

2.72

1.94

3.5

2.1

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

2.72

1.94

3.6

2.2

—

(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma

107

2.25

1.89

3.1

4.9

2.47

2.58

mg/l

0.09

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

2.30

1.81

4.1

4.5

—

(40758558) Short blood count panel - Blood

170

2.10

1.76

10.3

12.2

—

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

3.44

1.72

2.0

1.5

—

(3013115) Eosinophils [#/volume] in Blood

269

2.21

1.69

12.8

13.7

0.21

0.24

e9/l

0.31

216

(3000991) Gas panel - Venous blood

121

2.09

1.63

11.8

12.8

—

(1761868) Lipid panel - Serum or Plasma

2.69

1.62

2.1

1.4

—

(3022145) Colonoscopy Study observation

3.58

1.56

1.2

1.7

—

(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection

3.58

1.56

2.2

1.6

—

(40760892) CBC W Ordered Manual Differential panel - Blood

244

2.04

1.52

15.6

13.3

—

(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma

2.64

1.45

1.3

2.3

—

(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma

2.64

1.45

1.3

2.3

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

2.23

1.42

1.4

1.9

—

(3000963) Hemoglobin [Mass/volume] in Blood

463

+∞

1.41

33.4

18.0

132.32

129.13

g/l

0.56

457

(3009542) Hematocrit [Volume Fraction] of Blood

463

+∞

1.41

33.2

19.6

39.41

38.34

0.75

446

(3024731) MCV [Entitic volume]

463

+∞

1.41

32.6

17.7

85.99

84.71

0.88

457

(3035941) MCH [Entitic mass]

463

+∞

1.41

32.6

17.7

29.09

28.49

0.99

457

(3013139) Helicobacter pylori Ag [Presence] in Stool

3.15

1.39

1.0

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

3.15

1.39

2.0

1.6

—

(3044889) 12 lead EKG panel

119

1.96

1.38

2.1

1.7

—

(4035726) Immunohistochemistry procedure

2.97

1.31

2.0

1.7

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

203

1.86

1.29

1.9

2.2

—

(21493690) Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood

2.81

1.24

3.8

5.6

—

(21494815) CD4 cells/100 lymphocytes in Specimen

2.81

1.24

3.8

5.5

35.94

39.05

—

(3037467) Urinalysis macro (dipstick) panel - Urine

226

1.82

1.19

9.2

4.4

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

151

1.82

1.19

3.6

2.8

0.89

1.15

mmol/l

1.91

143

(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells

2.66

1.18

1.2

3.8

—

(3027831) CD3-CD16+CD56+ (Natural killer) cells/100 cells in Blood

2.66

1.18

3.8

5.4

14.80

9.40

—

(1175426) CD3 cells/100 lymphocytes in Blood

2.66

1.18

3.8

5.3

64.40

69.60

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

135

1.80

1.13

4.2

3.9

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

155

1.75

1.07

12.6

5.4

—

(3005719) IgG [Mass/volume] in Serum or Plasma

2.06

1.05

3.6

5.0

11.15

7.63

g/l

—

(3006315) Basophils [#/volume] in Blood

265

1.72

0.97

12.6

12.3

0.04

e9/l

0.21

205

(3001604) Monocytes [#/volume] in Blood

265

1.72

0.97

12.6

12.3

0.54

0.59

e9/l

0.69

205

(3030467) Casts [#/volume] in Urine by Automated count

141

1.70

0.95

13.6

5.3

1.08

0.14

e6/l

0.44

104

(3026008) Bacteria identified in Urine by Culture

1.80

0.94

9.4

3.0

—

(3031040) Bacteria [#/volume] in Urine by Automated count

217

1.66

0.93

10.8

4.1

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

403

2.16

0.90

25.6

11.7

29.15

25.31

mg/l

0.24

271

(40768797) Stomach Pathology biopsy report

2.06

0.87

1.7

1.4

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

162

1.64

0.87

39.4

16.8

25.04

24.74

mmol/l

0.25

162

(3019198) Lymphocytes [#/volume] in Blood

270

1.65

0.86

12.7

12.2

2.31

2.75

e9/l

1.03

220

(3013650) Neutrophils [#/volume] in Blood by Automated count

281

1.66

0.84

14.0

14.2

2.73

3.36

e9/l

1.30

223

(3021589) Normoblasts [#/volume] in Blood

272

1.63

0.81

14.8

13.5

0.00

0.05

e9/l

0.46

193

(3024354) Oxygen [Partial pressure] in Venous blood

128

1.63

0.81

12.1

14.0

5.13

5.30

kpa

0.20

128

(3002582) Erythrocytes [#/volume] in Urine

149

1.57

0.74

13.7

5.1

16.63

55.05

e6/l

0.90

111

(3018095) Leukocytes [#/volume] in Urine

168

1.55

0.73

15.2

6.1

90.48

25.22

e6/l

0.39

112

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

2.02

0.73

6.0

2.3

—

(36304419) Bacteria [Presence] in Urine

142

1.55

0.68

14.1

5.2

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

1.69

0.68

3.7

22.4

107.71

105.75

mmol/l

—

(3035933) Granulocytes/100 leukocytes in Blood

0.00

0.62

0.0

1.4

—

(3037522) Nuclear Ab [Titer] in Serum

1.81

0.60

1.2

1.4

—

(3007628) Bicarbonate [Moles/volume] standard in Venous blood

128

1.50

0.58

11.3

12.5

24.24

23.11

mmol/l

1.57

128

(3011397) Hemoglobin [Presence] in Urine by Test strip

102

1.52

0.55

4.8

3.9

—

(3041096) Erythrocytes [Presence] in Urine by Automated

1.40

0.43

11.9

2.4

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

0.42

0.0

1.9

—

(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay

0.00

0.42

0.0

8.1

—

0.31

—

(3015076) Soybean IgE Ab [Units/volume] in Serum

0.00

0.42

0.0

1.4

—

2.88

—

(3011897) Casein IgE Ab [Units/volume] in Serum

0.00

0.41

0.0

2.4

—

4.59

—

(40768804) Tissue Pathology biopsy report

1.42

0.41

1.9

1.7

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

1.42

0.41

1.0

1.1

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

1.42

0.41

8.7

5.2

1.86

1.61

e6/l

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

0.40

0.0

1.7

—

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

150

1.31

0.32

3.7

2.9

32.73

35.72

mmol/mol

0.89

136

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.32

0.31

1.1

1.4

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

1.30

0.28

1.6

1.7

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

1.31

0.26

9.2

5.5

1.50

0.47

e6/l

—

(36660697) Celiac disease serology panel - Serum

101

0.75

0.24

1.0

1.2

—

(3014326) Insulin-like growth factor-I [Moles/volume] in Serum or Plasma

1.21

0.22

6.6

4.6

15.40

20.86

nmol/l

—

(3022670) pH of Venous cord blood

0.00

0.21

0.0

1.0

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

0.00

0.21

0.0

1.9

—

(3007566) Smooth muscle Ab [Titer] in Serum

0.00

0.21

0.0

1.3

—

(3000330) Specific gravity of Urine by Test strip

0.00

0.21

0.0

1.4

—

(3037551) Cancer Ag 125 [Units/volume] in Serum or Plasma

0.00

0.21

0.0

2.4

—

36.40

—

(3024471) HLA-A [Type]

0.00

0.21

0.0

1.0

—

(3024932) HLA-DR beta [Type]

0.00

0.21

0.0

1.0

—

(3034770) Mitochondria Ab [Titer] in Serum

0.00

0.21

0.0

1.3

—

(3011648) Oxygen content in Venous blood

0.00

0.21

0.0

44.0

—

11.35

—

(3027231) Wheat IgE Ab [Units/volume] in Serum

0.00

0.21

0.0

1.5

—

5.50

—

(3024980) IgG subclass 4 [Mass/volume] in Serum

0.00

0.21

0.0

1.6

—

0.68

—

(40765089) Chromosome analysis panel - Blood by G-banded

0.00

0.20

0.0

1.0

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

1.17

0.20

2.2

1.8

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

1.25

0.18

1.7

1.9

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

1.25

0.18

9.3

3.0

—

(3009508) Creatinine [Moles/volume] in Urine

1.26

0.17

7.5

7.0

4.69

7.55

mmol/l

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.19

0.16

1.9

2.5

—

(3013707) Erythrocyte sedimentation rate by Westergren method

242

1.15

0.13

5.1

4.7

6.95

8.44

mm/h

0.33

222

(3003694) ABO and Rh group [Type] in Blood

134

1.17

0.12

1.8

1.5

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

1.12

0.07

2.1

2.7

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

415

0.93

0.07

4.1

3.8

—

(3007164) IgA [Mass/volume] in Serum or Plasma

201

0.91

0.06

2.1

1.8

1.63

1.33

g/l

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

141

0.99

0.00

2.8

2.1

—

(3012336) Haptoglobin [Mass/volume] in Serum or Plasma

0.00

0.0

1.7

—

0.83

—

(21494429) FMR1 gene CGG repeat analysis in Blood or Tissue by Molecular genetics method

0.00

0.0

1.0

—

(3018405) Lactate [Moles/volume] in Arterial blood

0.00

0.0

7.5

—

1.74

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

0.00

0.0

1.0

—

(3042733) HLA Ab [Presence] in Serum

0.00

0.0

2.3

—

(3042111) Morphology [Interpretation] in Bone marrow Narrative

0.00

0.0

5.2

—

(1001509) Gas and Carbon monoxide and Electrolytes panel - Arterial blood

0.00

-0.00

0.0

3.8

—

(40762485) Glomerular basement membrane Ab [Units/volume] in Serum by Immunoassay

0.00

-0.00

0.0

2.4

—

(44816559) Phosphatidylethanol [Mass/volume] in Blood

0.00

-0.00

0.0

1.3

—

(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(3000093) Morphology [Interpretation] in Blood Narrative

0.00

-0.00

0.0

1.1

—

(3045414) Leukocytes [Presence] in Urine

0.00

-0.00

0.0

1.3

—

(3019832) Treponema pallidum Ab [Presence] in Serum

0.86

-0.00

2.0

1.7

—

(3022493) Free Hemoglobin [Mass/volume] in Plasma

0.00

-0.00

0.0

2.1

—

67.00

—

(3028192) IgG subclass 2 [Mass/volume] in Serum

0.00

-0.00

0.0

1.4

—

2.45

—

(3023659) Complement C1 esterase inhibitor.functional/Complement C1 esterase inhibitor.total in Serum or Plasma

0.00

-0.00

0.0

1.0

—

112.50

—

(3027135) IgG subclass 1 [Mass/volume] in Serum

0.00

-0.00

0.0

1.4

—

5.17

—

(3015024) Glucose [Moles/volume] in Serum or Plasma --1 hour post dose glucose

0.00

-0.00

0.0

2.2

—

7.16

—

(3029634) Reagin Ab [Titer] in Serum by VDRL

0.00

-0.00

0.0

1.3

—

(3014051) Protein [Presence] in Urine by Test strip

0.00

-0.00

0.0

1.4

—

(40761873) Peanut recombinant (rAra h) 1 IgE Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

1.00

-0.00

2.2

2.0

—

(4062490) Immunoglobulin typing, IgG

0.00

-0.00

0.0

1.4

—

(3026820) Hemoglobin [Mass/volume] in Venous cord blood

0.00

-0.00

0.0

1.0

—

175.71

—

(44816893) Food Allergen Mix 50 (Kiwi+Pineapple+Banana+Mango) IgE Ab [Units/volume] in Serum by Multidisk

0.00

-0.00

0.0

1.0

—

(3016031) Almond IgE Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.3

—

3.39

—

(40761871) Peanut recombinant (rAra h) 3 IgE Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method

0.00

-0.00

0.0

1.3

—

(40765096) Chromosome analysis panel by Banding

0.00

-0.00

0.0

1.2

—

(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(1175556) inFLIXimab Ab [Units/volume] in Serum by Immunoassay

0.00

-0.00

0.0

10.4

—

(3012413) Glucose [Moles/volume] in Serum or Plasma --2 hours post meal

0.00

-0.00

0.0

2.0

—

5.80

—

Mortality – FinRegistry

↥

Association

Association between endpoint P16_INTRACR_NONTRAU_HAEMORRHAGE_FETUS_NEWBO and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have P16_INTRACR_NONTRAU_HAEMORRHAGE_FETUS_NEWBO.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: P16_INTRACR_NONTRAU_HAEMORRHAGE_FETUS_NEWBO – Intracranial nontraumatic haemorrhage of fetus and newborn

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Intracranial nontraumatic haemorrhage of fetus and newborn

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints